Stephen F. Konieczny, PhD - Publications

Affiliations: 
Biological Sciences Purdue University, West Lafayette, IN, United States 

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wöhner M, Pinter T, Bönelt P, Hagelkruys A, Kostanova-Poliakova D, Stadlmann J, Konieczny SF, Fischer M, Jaritz M, Busslinger M. The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells. Frontiers in Immunology. 13: 859598. PMID 36618345 DOI: 10.3389/fimmu.2022.859598  0.315
2022 Zhang Z, Cheng L, Li J, Qiao Q, Karki A, Allison DB, Shaker N, Li K, Utturkar SM, Atallah Lanman NM, Rao X, Rychahou P, He D, Konieczny SF, Wang C, et al. Targeting Plk1 sensitizes pancreatic cancer to immune checkpoint therapy. Cancer Research. PMID 35950917 DOI: 10.1158/0008-5472.CAN-22-0018  0.384
2021 Venis SM, Moon HR, Yang Y, Utturkar SM, Konieczny SF, Han B. Engineering of a functional pancreatic acinus with reprogrammed cancer cells by induced expression. Lab On a Chip. 21: 3675-3685. PMID 34581719 DOI: 10.1039/d1lc00350j  0.717
2020 Schweickert PG, Wang N, Sandefur SL, Lloyd ME, Konieczny SF, Frye C, Cheng Z. CRISPR/Ca12a-mediated CHO genome engineering can be effectively integrated at multiple stages of the cell line generation process for bioproduction. Biotechnology Journal. e2000308. PMID 33369118 DOI: 10.1002/biot.202000308  0.376
2020 Schweickert PG, Yang Y, White EE, Cresswell GM, Elzey BD, Ratliff TL, Arumugam P, Antoniak S, Mackman N, Flick MJ, Konieczny SF. Thrombin-PAR1 signaling in pancreatic cancer promotes an immunosuppressive microenvironment. Journal of Thrombosis and Haemostasis : Jth. PMID 33064371 DOI: 10.1111/jth.15115  0.747
2020 Moon HR, Ozcelikkale A, Yang Y, Elzey BD, Konieczny SF, Han B. An engineered pancreatic cancer model with intra-tumoral heterogeneity of driver mutations. Lab On a Chip. PMID 32909573 DOI: 10.1039/D0Lc00707B  0.712
2020 Moon HR, Ospina-Muñoz N, Noe-Kim V, Yang Y, Elzey BD, Konieczny SF, Han B. Subtype-specific characterization of breast cancer invasion using a microfluidic tumor platform. Plos One. 15: e0234012. PMID 32544183 DOI: 10.1371/Journal.Pone.0234012  0.679
2020 Bradney MJ, Venis SM, Yang Y, Konieczny SF, Han B. A Biomimetic Tumor Model of Heterogeneous Invasion in Pancreatic Ductal Adenocarcinoma. Small (Weinheim An Der Bergstrasse, Germany). e1905500. PMID 31997571 DOI: 10.1002/Smll.201905500  0.717
2019 Yang Y, Stang A, Schweickert PG, Lanman NA, Paul EN, Monia BP, Revenko AS, Palumbo JS, Mullins ES, Elzey BD, Janssen EM, Konieczny SF, Flick MJ. Thrombin signaling promotes pancreatic adenocarcinoma through PAR-1-dependent immune evasion. Cancer Research. PMID 31048498 DOI: 10.1158/0008-5472.Can-18-3206  0.782
2019 Shouksmith AE, Shah F, Grimard ML, Gawel JM, Raouf Y, Geletu M, Berger-Becvar A, de Araujo ED, Luchman HA, Heaton WL, Bakhshinyan D, Adile AA, Venugopal C, O'Hare T, Deininger MW, ... ... Konieczny SF, et al. Identification and Characterization of AES-135, a Hydroxamic Acid-based HDAC Inhibitor that Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer. Journal of Medicinal Chemistry. PMID 30776234 DOI: 10.1021/Acs.Jmedchem.8B01957  0.418
2018 Pitarresi JR, Liu X, Avendano A, Thies KA, Sizemore GM, Hammer AM, Hildreth BE, Wang DJ, Steck SA, Donohue S, Cuitiño MC, Kladney RD, Mace TA, Chang JJ, Ennis CS, ... ... Konieczny SF, et al. Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth. Life Science Alliance. 1: e201800190. PMID 30456390 DOI: 10.26508/lsa.201800190  0.4
2018 Morman RE, Schweickert PG, Konieczny SF, Taparowsky EJ. BATF regulates the expression of Nfil3, Wnt10a and miR155hg for efficient induction of antibody class switch recombination in mice. European Journal of Immunology. PMID 29898247 DOI: 10.1002/Eji.201747360  0.529
2018 Jakubison BL, Schweickert PG, Moser SE, Yang Y, Gao H, Scully K, Itkin-Ansari P, Liu Y, Konieczny SF. Induced ptf1a expression in pancreatic ductal adenocarcinoma cellsactivates acinar gene networks, reduces tumorigenic properties,and sensitizes cells to gemcitabine treatment. Molecular Oncology. PMID 29719936 DOI: 10.1002/1878-0261.12314  0.675
2017 Sakitani K, Hayakawa Y, Deng H, Ariyama H, Kinoshita H, Konishi M, Ono S, Suzuki N, Ihara S, Niu Z, Kim W, Tanaka T, Liu H, Chen X, Tailor Y, ... ... Konieczny SF, et al. CXCR4-expressing Mist1+ progenitors in the gastric antrum contribute to gastric cancer development. Oncotarget. 8: 111012-111025. PMID 29340033 DOI: 10.18632/Oncotarget.22451  0.496
2017 Lo HG, Jin RU, Sibbel G, Liu D, Karki A, Joens MS, Madison BB, Zhang B, Blanc V, Fitzpatrick JA, Davidson NO, Konieczny SF, Mills JC. A single transcription factor is sufficient to induce and maintain secretory cell architecture. Genes & Development. PMID 28174210 DOI: 10.1101/Gad.285684.116  0.56
2016 Pitarresi JR, Liu X, Sharma SM, Cuitiño MC, Kladney RD, Mace TA, Donohue S, Nayak SG, Qu C, Lee J, Woelke SA, Trela S, LaPak K, Yu L, McElroy J, ... ... Konieczny SF, et al. Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. Neoplasia (New York, N.Y.). 18: 541-52. PMID 27659014 DOI: 10.1016/J.Neo.2016.07.006  0.551
2016 Jiang M, Azevedo-Pouly A, Deering TG, Hoang CQ, DiRenzo D, Hess DA, Konieczny SF, Swift GH, MacDonald RJ. MIST1 and PTF1 Collaborate in Feed-forward Regulatory Loops that Maintain the Pancreatic Acinar Phenotype in Adult Mice. Molecular and Cellular Biology. PMID 27644326 DOI: 10.1128/Mcb.00370-16  0.817
2016 Hess DA, Strelau KM, Karki A, Jiang M, Azevedo-Pouly AC, Lee AH, Deering TG, Hoang CQ, MacDonald RJ, Konieczny SF. MIST1 Links Secretion and Stress as Both Target and Regulator of the UPR. Molecular and Cellular Biology. PMID 27644325 DOI: 10.1128/Mcb.00366-16  0.656
2016 Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, ... ... Konieczny SF, et al. Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. Genes & Development. PMID 27633013 DOI: 10.1101/Gad.283499.116  0.557
2016 Bi P, Yue F, Karki A, Castro B, Wirbisky SE, Wang C, Durkes A, Elzey BD, Andrisani OM, Bidwell CA, Freeman JL, Konieczny SF, Kuang S. Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice. The Journal of Experimental Medicine. PMID 27573812 DOI: 10.1084/Jem.20160157  0.413
2016 Li J, Gu D, Lee SS, Song B, Bandyopadhyay S, Chen S, Konieczny SF, Ratliff TL, Liu X, Xie J, Cheng JX. Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer. Oncogene. PMID 27132508 DOI: 10.1038/Onc.2016.168  0.44
2016 Li J, Wang R, Schweickert PG, Karki A, Yang Y, Kong Y, Ahmad N, Konieczny SF, Liu X. Plk1 Inhibition Enhances the Efficacy of Gemcitabine in Human Pancreatic Cancer. Cell Cycle (Georgetown, Tex.). 0. PMID 26890815 DOI: 10.1080/15384101.2016.1148838  0.558
2016 Zimmers TA, Jiang Y, Liu J, Ceppa E, Nakeeb A, House M, Zyromski N, Schmidt CM, Hannaford K, Schloss D, Brooks C, Radovich M, Lui Y, Jiang G, Konieczny SF, et al. Abstract B35: Molecular and phenotypic profiling of pancreatic cancer cachexia in novel murine models and patients Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B35  0.399
2015 Karki A, Humphrey SE, Steele RE, Hess DA, Taparowsky EJ, Konieczny SF. Silencing Mist1 Gene Expression Is Essential for Recovery from Acute Pancreatitis. Plos One. 10: e0145724. PMID 26717480 DOI: 10.1371/Journal.Pone.0145724  0.7
2015 Han B, Qu C, Park K, Korc M, Konieczny SF. Recapitulation of complex transport and action of drugs at tumor microenvironment using tumor-microenvironment-on-chip. Cancer Letters. PMID 26688098 DOI: 10.1016/J.Canlet.2015.12.003  0.622
2015 Zhou Z, Yang Y, Konieczny SF, Irudayaraj JM. Rapid and unbiased extraction of chromatin associated RNAs from purified native chromatin. Journal of Chromatography. A. PMID 26643718 DOI: 10.1016/J.Chroma.2015.11.067  0.475
2015 Hayakawa Y, Ariyama H, Stancikova J, Sakitani K, Asfaha S, Renz BW, Dubeykovskaya ZA, Shibata W, Wang H, Westphalen CB, Chen X, Takemoto Y, Kim W, Khurana SS, Tailor Y, ... ... Konieczny SF, et al. Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche. Cancer Cell. PMID 26585400 DOI: 10.1016/J.Ccell.2015.10.003  0.452
2015 Li J, Karki A, Hodges KB, Ahmad N, Zoubeidi A, Strebhardt K, Ratliff TL, Konieczny SF, Liu X. Co-targeting Polo-like kinase 1(Plk1) and the Wnt/β-catenin signaling pathway in castration-resistant prostate cancer. Molecular and Cellular Biology. PMID 26438599 DOI: 10.1128/Mcb.00825-15  0.396
2015 Kim S, Lahmy R, Riha C, Yang C, Jakubison BL, van Niekerk J, Staub C, Wu Y, Gates K, Dong DS, Konieczny SF, Itkin-Ansari P. The Basic Helix-Loop-Helix Transcription Factor E47 Reprograms Human Pancreatic Cancer Cells to a Quiescent Acinar State With Reduced Tumorigenic Potential. Pancreas. 44: 718-27. PMID 25894862 DOI: 10.1097/Mpa.0000000000000328  0.579
2015 Aure MH, Konieczny SF, Ovitt CE. Salivary gland homeostasis is maintained through acinar cell self-duplication. Developmental Cell. 33: 231-7. PMID 25843887 DOI: 10.1016/J.Devcel.2015.02.013  0.503
2015 Flick MJ, Rewerts C, Cruz C, Palumbo JS, Luyendyk JP, Yang Y, Konieczny SF. Tumor Cell Thrombin/PAR-1 Signaling Drives Pancreatic Ductal Adenocarcinoma Growth and Dissemination Blood. 126: 1070-1070. DOI: 10.1182/Blood.V126.23.1070.1070  0.776
2015 Li J, Lee S, Gu D, Song B, Chen S, Konieczny S, Ratliff T, Liu X, Xie J, Cheng J. Abstract B50: Abrogating cholesterol esterification suppresses pancreatic cancer growth and metastasis mediated by caveolin-1 Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B50  0.441
2015 Kim S, Yang C, Riha C, Lamy R, Jakubison BL, Konieczny SF, Itkin-Ansari P. Abstract A13: Mechanisms of E47 induced quiescence and acinar cell differentiation in human pancreatic cancer cells Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A13  0.583
2015 Pyronnet S, Lasfargues C, Martineau Y, Müller D, Hess DA, DiRenzo D, Khoutorsky A, Baer R, Guillermet-Guibert J, Sonenberg N, Konieczny SF, Bousquet C. Translational regulation of exocrine cell function and survival by ATF4-dependent expression of 4E-BP1 Pancreatology. 15: S48. DOI: 10.1016/J.Pan.2015.05.196  0.789
2014 Li Z, Li J, Bi P, Lu Y, Burcham G, Elzey BD, Ratliff T, Konieczny SF, Ahmad N, Kuang S, Liu X. Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state. Molecular and Cellular Biology. 34: 3642-61. PMID 25047839 DOI: 10.1128/Mcb.00814-14  0.433
2014 Lee H, Kim Y, Schweickert PG, Konieczny SF, Won YY. A photo-degradable gene delivery system for enhanced nuclear gene transcription. Biomaterials. 35: 1040-9. PMID 24172855 DOI: 10.1016/J.Biomaterials.2013.10.030  0.446
2013 Qu C, Konieczny SF. Pancreatic Acinar Cell 3-Dimensional Culture. Bio-Protocol. 3. PMID 27453905  0.362
2013 Song B, Liu XS, Rice SJ, Kuang S, Elzey BD, Konieczny SF, Ratliff TL, Hazbun T, Chiorean EG, Liu X. Plk1 phosphorylation of orc2 and hbo1 contributes to gemcitabine resistance in pancreatic cancer. Molecular Cancer Therapeutics. 12: 58-68. PMID 23188630 DOI: 10.1158/1535-7163.Mct-12-0632  0.444
2013 Shi G, DiRenzo D, Qu C, Barney D, Miley D, Konieczny SF. Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia. Oncogene. 32: 1950-8. PMID 22665051 DOI: 10.1038/Onc.2012.210  0.817
2012 Direnzo D, Hess DA, Damsz B, Hallett JE, Marshall B, Goswami C, Liu Y, Deering T, Macdonald RJ, Konieczny SF. Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells. Gastroenterology. 143: 469-80. PMID 22510200 DOI: 10.1053/J.Gastro.2012.04.011  0.824
2012 Godby RC, Van Den Berg YW, Srinivasan R, Sturm R, Hui DY, Konieczny SF, Aronow BJ, Ozhegov E, Ruf W, Versteeg HH, Bogdanov VY. Nonproteolytic properties of murine alternatively spliced tissue factor: implications for integrin-mediated signaling in murine models. Molecular Medicine (Cambridge, Mass.). 18: 771-9. PMID 22481268 DOI: 10.2119/Molmed.2011.00416  0.492
2012 Prévot PP, Simion A, Grimont A, Colletti M, Khalaileh A, Van den Steen G, Sempoux C, Xu X, Roelants V, Hald J, Bertrand L, Heimberg H, Konieczny SF, Dor Y, Lemaigre FP, et al. Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia. Gut. 61: 1723-32. PMID 22271799 DOI: 10.1136/Gutjnl-2011-300266  0.595
2012 Liu XS, Song B, Elzey BD, Ratliff TL, Konieczny SF, Cheng L, Liu X. Abstract 233: Polo-like kinase 1 facilitates loss of Pten-induced prostate cancer formation Cancer Research. 72: 233-233. DOI: 10.1158/1538-7445.Am2012-233  0.419
2011 Liu XS, Song B, Elzey BD, Ratliff TL, Konieczny SF, Cheng L, Ahmad N, Liu X. Polo-like kinase 1 facilitates loss of Pten tumor suppressor-induced prostate cancer formation. The Journal of Biological Chemistry. 286: 35795-800. PMID 21890624 DOI: 10.1074/Jbc.C111.269050  0.427
2011 Hess DA, Humphrey SE, Ishibashi J, Damsz B, Lee AH, Glimcher LH, Konieczny SF. Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice. Gastroenterology. 141: 1463-72. PMID 21704586 DOI: 10.1053/J.Gastro.2011.06.045  0.669
2011 Coon BG, Direnzo DM, Konieczny SF, Aguilar RC. Epsins' novel role in cancer cell invasion. Communicative & Integrative Biology. 4: 95-7. PMID 21509192 DOI: 10.4161/Cib.14129  0.764
2011 Gary DJ, Lee H, Sharma R, Lee JS, Kim Y, Cui ZY, Jia D, Bowman VD, Chipman PR, Wan L, Zou Y, Mao G, Park K, Herbert BS, Konieczny SF, et al. Influence of nano-carrier architecture on in vitro siRNA delivery performance and in vivo biodistribution: polyplexes vs micelleplexes. Acs Nano. 5: 3493-505. PMID 21456626 DOI: 10.1021/Nn102540Y  0.572
2011 Won Y, Sharma R, Konieczny SF. Corrigendum to “Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes” [J. Control. Release 139 (2) (2009) 88–93] Journal of Controlled Release. 152: 326. DOI: 10.1016/J.Jconrel.2011.04.003  0.33
2010 Nam KT, Lee HJ, Sousa JF, Weis VG, O'Neal RL, Finke PE, Romero-Gallo J, Shi G, Mills JC, Peek RM, Konieczny SF, Goldenring JR. Mature chief cells are cryptic progenitors for metaplasia in the stomach. Gastroenterology. 139: 2028-2037.e9. PMID 20854822 DOI: 10.1053/J.Gastro.2010.09.005  0.636
2010 Huh WJ, Esen E, Geahlen JH, Bredemeyer AJ, Lee AH, Shi G, Konieczny SF, Glimcher LH, Mills JC. XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum. Gastroenterology. 139: 2038-49. PMID 20816838 DOI: 10.1053/J.Gastro.2010.08.050  0.663
2010 Garside VC, Kowalik AS, Johnson CL, DiRenzo D, Konieczny SF, Pin CL. MIST1 regulates the pancreatic acinar cell expression of Atp2c2, the gene encoding secretory pathway calcium ATPase 2. Experimental Cell Research. 316: 2859-70. PMID 20599950 DOI: 10.1016/J.Yexcr.2010.06.014  0.782
2009 Won YY, Sharma R, Konieczny SF. Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 139: 88-93. PMID 19580830 DOI: 10.1016/J.Jconrel.2009.06.031  0.446
2009 Shi G, Zhu L, Sun Y, Bettencourt R, Damsz B, Hruban RH, Konieczny SF. Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia. Gastroenterology. 136: 1368-78. PMID 19249398 DOI: 10.1053/J.Gastro.2008.12.066  0.791
2009 DiRenzo D, Shi G, Konieczny SF. Abstract A76: A novelin vivomodel for pancreatic restructuring and suppression of transformation Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A76  0.812
2009 Shi G, DiRenzo D, Konieczny SF. Abstract A71: Distinct functions of epithelial growth factor receptor (EGFR) pathways in pancreatic acinar cell differentiation and initiation of pancreatic ductal adenocarcinoma Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A71  0.805
2009 Nam KT, Lee H, Mills JC, Konieczny SF, Goldenring JR. S1941 Gastric Chief Cells As a Cryptic Progenitor for Transdifferentiation Into SPEM Induced By Oxyntic Atrophy Gastroenterology. 136: A-297-A-298. DOI: 10.1016/S0016-5085(09)61356-1  0.399
2009 Huh WJ, Esen E, Bredemeyer A, Shi G, Lee A, Konieczny SF, Glimcher LH, Mills JC. 863 XBP1 Is Required for the Maturation and the Maintenance of Digestive-Enzyme Secreting Zymogenic (Chief) Cells Gastroenterology. 136: A-132. DOI: 10.1016/S0016-5085(09)60592-8  0.584
2008 Habbe N, Shi G, Meguid RA, Fendrich V, Esni F, Chen H, Feldmann G, Stoffers DA, Konieczny SF, Leach SD, Maitra A. Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 18913-8. PMID 19028870 DOI: 10.1073/Pnas.0810097105  0.629
2008 Sharma R, Lee JS, Bettencourt RC, Xiao C, Konieczny SF, Won YY. Effects of the incorporation of a hydrophobic middle block into a PEG-polycation diblock copolymer on the physicochemical and cell interaction properties of the polymer-DNA complexes. Biomacromolecules. 9: 3294-307. PMID 18942877 DOI: 10.1021/Bm800876V  0.377
2008 Jia D, Sun Y, Konieczny SF. Mist1 regulates pancreatic acinar cell proliferation through p21 CIP1/WAF1. Gastroenterology. 135: 1687-97. PMID 18762186 DOI: 10.1053/J.Gastro.2008.07.026  0.683
2008 Rovira M, Delaspre F, Massumi M, Serra SA, Valverde MA, Lloreta J, Dufresne M, Payré B, Konieczny SF, Savatier P, Real FX, Skoudy A. Murine embryonic stem cell-derived pancreatic acinar cells recapitulate features of early pancreatic differentiation. Gastroenterology. 135: 1301-1310, 1310.e1-5. PMID 18725222 DOI: 10.1053/J.Gastro.2008.06.049  0.575
2008 Nozaki K, Ogawa M, Williams JA, Lafleur BJ, Ng V, Drapkin RI, Mills JC, Konieczny SF, Nomura S, Goldenring JR. A molecular signature of gastric metaplasia arising in response to acute parietal cell loss. Gastroenterology. 134: 511-22. PMID 18242217 DOI: 10.1053/J.Gastro.2007.11.058  0.54
2007 Konieczny SF, Leach SD. Metaplastic metamorphoses in the mammalian pancreas. Gastroenterology. 133: 2056-9. PMID 18054579 DOI: 10.1053/J.Gastro.2007.10.061  0.412
2007 Tran T, Jia D, Sun Y, Konieczny SF. The bHLH domain of Mistl is sufficient to activate gene transcription. Gene Expression. 13: 241-53. PMID 17605298 DOI: 10.3727/000000006780666975  0.725
2007 Zhu L, Shi G, Schmidt CM, Hruban RH, Konieczny SF. Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia. The American Journal of Pathology. 171: 263-73. PMID 17591971 DOI: 10.2353/Ajpath.2007.061176  0.783
2007 Ramsey VG, Doherty JM, Chen CC, Stappenbeck TS, Konieczny SF, Mills JC. The maturation of mucus-secreting gastric epithelial progenitors into digestive-enzyme secreting zymogenic cells requires Mist1. Development (Cambridge, England). 134: 211-22. PMID 17164426 DOI: 10.1242/Dev.02700  0.53
2006 Mitin N, Konieczny SF, Taparowsky EJ. RAS and the RAIN/RasIP1 effector. Methods in Enzymology. 407: 322-35. PMID 16757335 DOI: 10.1016/S0076-6879(05)07027-8  0.36
2006 Zhao Y, Johansson C, Tran T, Bettencourt R, Itahana Y, Desprez PY, Konieczny SF. Identification of a basic helix-loop-helix transcription factor expressed in mammary gland alveolar cells and required for maintenance of the differentiated state. Molecular Endocrinology (Baltimore, Md.). 20: 2187-98. PMID 16645041 DOI: 10.1210/Me.2005-0214  0.694
2006 Tuveson DA, Zhu L, Gopinathan A, Willis NA, Kachatrian L, Grochow R, Pin CL, Mitin NY, Taparowsky EJ, Gimotty PA, Hruban RH, Jacks T, Konieczny SF. Mist1-KrasG12D knock-in mice develop mixed differentiation metastatic exocrine pancreatic carcinoma and hepatocellular carcinoma. Cancer Research. 66: 242-7. PMID 16397237 DOI: 10.1158/0008-5472.Can-05-2305  0.707
2005 Luo X, Shin DM, Wang X, Konieczny SF, Muallem S. Aberrant localization of intracellular organelles, Ca2+ signaling, and exocytosis in Mist1 null mice. The Journal of Biological Chemistry. 280: 12668-75. PMID 15665001 DOI: 10.1074/Jbc.M411973200  0.347
2004 Mitin NY, Ramocki MB, Zullo AJ, Der CJ, Konieczny SF, Taparowsky EJ. Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization. The Journal of Biological Chemistry. 279: 22353-61. PMID 15031288 DOI: 10.1074/Jbc.M312867200  0.359
2004 Zhu L, Tran T, Rukstalis JM, Sun P, Damsz B, Konieczny SF. Inhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasia. Molecular and Cellular Biology. 24: 2673-81. PMID 15024058 DOI: 10.1128/Mcb.24.7.2673-2681.2004  0.825
2003 Rukstalis JM, Kowalik A, Zhu L, Lidington D, Pin CL, Konieczny SF. Exocrine specific expression of Connexin32 is dependent on the basic helix-loop-helix transcription factor Mist1. Journal of Cell Science. 116: 3315-25. PMID 12829745 DOI: 10.1242/Jcs.00631  0.815
2002 Pin CL, Konieczny SF. A fast fiber enhancer exists in the muscle regulatory factor 4 gene promoter. Biochemical and Biophysical Research Communications. 299: 7-13. PMID 12435381 DOI: 10.1016/S0006-291X(02)02571-8  0.528
2002 Wyzykowski JC, Winata TI, Mitin N, Taparowsky EJ, Konieczny SF. Identification of novel MyoD gene targets in proliferating myogenic stem cells. Molecular and Cellular Biology. 22: 6199-208. PMID 12167713 DOI: 10.1128/Mcb.22.17.6199-6208.2002  0.545
2002 Flick MJ, Konieczny SF. Identification of putative mammalian D-lactate dehydrogenase enzymes. Biochemical and Biophysical Research Communications. 295: 910-6. PMID 12127981 DOI: 10.1016/S0006-291X(02)00768-4  0.729
2002 Evtushenko OO, Konieczny S, Semerak VM. Investigation of the temperature field induced in the process of friction of a wheel against a rail Materials Science. 38: 709-716. DOI: 10.1023/A:1024218608605  0.197
2001 Pin CL, Rukstalis JM, Johnson C, Konieczny SF. The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. The Journal of Cell Biology. 155: 519-30. PMID 11696558 DOI: 10.1083/Jcb.200105060  0.827
2001 Mitin N, Ramocki MB, Konieczny SF, Taparowsky EJ. Ras regulation of skeletal muscle differentiation and gene expression. Methods in Enzymology. 333: 232-47. PMID 11400339 DOI: 10.1016/S0076-6879(01)33059-8  0.516
2001 Mitin N, Kudla AJ, Konieczny SF, Taparowsky EJ. Differential effects of Ras signaling through NFkappaB on skeletal myogenesis. Oncogene. 20: 1276-86. PMID 11313872 DOI: 10.1038/Sj.Onc.1204223  0.399
2000 Pin CL, Bonvissuto AC, Konieczny SF. Mist1 expression is a common link among serous exocrine cells exhibiting regulated exocytosis. The Anatomical Record. 259: 157-67. PMID 10820318 DOI: 10.1002/(Sici)1097-0185(20000601)259:2<157::Aid-Ar6>3.0.Co;2-0  0.59
2000 Peña TL, Chen SH, Konieczny SF, Rane SG. Ras/MEK/ERK Up-regulation of the fibroblast KCa channel FIK is a common mechanism for basic fibroblast growth factor and transforming growth factor-beta suppression of myogenesis. The Journal of Biological Chemistry. 275: 13677-82. PMID 10788486 DOI: 10.1074/Jbc.275.18.13677  0.454
2000 Flick MJ, Konieczny SF. The muscle regulatory and structural protein MLP is a cytoskeletal binding partner of betaI-spectrin. Journal of Cell Science. 113: 1553-64. PMID 10751147  0.706
1999 Pin CL, Lemercier C, Konieczny SF. Cloning of the murine Mist1 gene and assignment to mouse chromosome band 5G2-5G3. Cytogenetics and Cell Genetics. 86: 219-22. PMID 10575209  0.315
1998 Ramocki MB, White MA, Konieczny SF, Taparowsky EJ. A role for RalGDS and a novel Ras effector in the Ras-mediated inhibition of skeletal myogenesis. The Journal of Biological Chemistry. 273: 17696-701. PMID 9651367 DOI: 10.1074/Jbc.273.28.17696  0.436
1998 Lemercier C, To RQ, Carrasco RA, Konieczny SF. The basic helix-loop-helix transcription factor Mist1 functions as a transcriptional repressor of myoD. The Embo Journal. 17: 1412-22. PMID 9482738 DOI: 10.1093/Emboj/17.5.1412  0.532
1997 Kong Y, Flick MJ, Kudla AJ, Konieczny SF. Muscle LIM protein promotes myogenesis by enhancing the activity of MyoD. Molecular and Cellular Biology. 17: 4750-60. PMID 9234731 DOI: 10.1128/Mcb.17.8.4750  0.75
1997 Ramocki MB, Johnson SE, White MA, Ashendel CL, Konieczny SF, Taparowsky EJ. Signaling through mitogen-activated protein kinase and Rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesis. Molecular and Cellular Biology. 17: 3547-55. PMID 9199290 DOI: 10.1128/Mcb.17.7.3547  0.407
1997 Lemercier C, To RQ, Swanson BJ, Lyons GE, Konieczny SF. Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern. Developmental Biology. 182: 101-13. PMID 9073453 DOI: 10.1006/Dbio.1996.8454  0.504
1997 Pin CL, Ludolph DC, Cooper ST, Klocke BJ, Merlie JP, Konieczny SF. Distal regulatory elements control MRF4 gene expression in early and late myogenic cell populations. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 208: 299-312. PMID 9056635 DOI: 10.1002/(Sici)1097-0177(199703)208:3<299::Aid-Aja2>3.0.Co;2-D  0.557
1996 Johnson SE, Wang X, Hardy S, Taparowsky EJ, Konieczny SF. Casein kinase II increases the transcriptional activities of MRF4 and MyoD independently of their direct phosphorylation. Molecular and Cellular Biology. 16: 1604-13. PMID 8657135 DOI: 10.1128/Mcb.16.4.1604  0.489
1996 Mak KL, Longcor LC, Johnson SE, Lemercier C, To RQ, Konieczny SF. Examination of mammalian basic helix-loop-helix transcription factors using a yeast one-hybrid system. Dna and Cell Biology. 15: 1-8. PMID 8561893 DOI: 10.1089/Dna.1996.15.1  0.511
1995 Ludolph DC, Konieczny SF. Transcription factor families: muscling in on the myogenic program. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 1595-604. PMID 8529839 DOI: 10.1096/Fasebj.9.15.8529839  0.495
1995 Naidu PS, Ludolph DC, To RQ, Hinterberger TJ, Konieczny SF. Myogenin and MEF2 function synergistically to activate the MRF4 promoter during myogenesis. Molecular and Cellular Biology. 15: 2707-18. PMID 7739551 DOI: 10.1128/Mcb.15.5.2707  0.547
1995 Kong Y, Johnson SE, Taparowsky EJ, Konieczny SF. Ras p21Val inhibits myogenesis without altering the DNA binding or transcriptional activities of the myogenic basic helix-loop-helix factors. Molecular and Cellular Biology. 15: 5205-13. PMID 7565669 DOI: 10.1128/Mcb.15.10.5205  0.506
1993 Hardy S, Kong Y, Konieczny SF. Fibroblast growth factor inhibits MRF4 activity independently of the phosphorylation status of a conserved threonine residue within the DNA-binding domain. Molecular and Cellular Biology. 13: 5943-56. PMID 8413199 DOI: 10.1128/Mcb.13.10.5943  0.479
1993 Smith TH, Block NE, Rhodes SJ, Konieczny SF, Miller JB. A unique pattern of expression of the four muscle regulatory factor proteins distinguishes somitic from embryonic, fetal and newborn mouse myogenic cells. Development (Cambridge, England). 117: 1125-33. PMID 8391976  0.47
1993 Voytik SL, Przyborski M, Badylak SF, Konieczny SF. Differential expression of muscle regulatory factor genes in normal and denervated adult rat hindlimb muscles. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 198: 214-24. PMID 8136525 DOI: 10.1002/Aja.1001980307  0.475
1992 Hinterberger TJ, Mays JL, Konieczny SF. Structure and myofiber-specific expression of the rat muscle regulatory gene MRF4. Gene. 117: 201-7. PMID 1639267 DOI: 10.1016/0378-1119(92)90730-D  0.497
1992 Yutzey KE, Konieczny SF. Different E-box regulatory sequences are functionally distinct when placed within the context of the troponin I enhancer. Nucleic Acids Research. 20: 5105-13. PMID 1329039 DOI: 10.1093/Nar/20.19.5105  0.732
1992 Mak KL, To RQ, Kong Y, Konieczny SF. The MRF4 activation domain is required to induce muscle-specific gene expression. Molecular and Cellular Biology. 12: 4334-46. PMID 1328851 DOI: 10.1128/Mcb.12.10.4334  0.502
1992 Vaidya TB, Rhodes SJ, Moore JL, Sherman DA, Konieczny SF, Taparowsky EJ. Isolation and structural analysis of the rat MyoD gene. Gene. 116: 223-30. PMID 1321778 DOI: 10.1016/0378-1119(92)90519-U  0.432
1992 Lin H, Konieczny SF. Identification of MRF4, myogenin, and E12 oligomer complexes by chemical cross-linking and two-dimensional gel electrophoresis. The Journal of Biological Chemistry. 267: 4773-80. PMID 1311321  0.359
1991 Lin H, Yutzey KE, Konieczny SF. Muscle-specific expression of the troponin I gene requires interactions between helix-loop-helix muscle regulatory factors and ubiquitous transcription factors. Molecular and Cellular Biology. 11: 267-80. PMID 1846022 DOI: 10.1128/Mcb.11.1.267  0.75
1991 Hinterberger TJ, Sassoon DA, Rhodes SJ, Konieczny SF. Expression of the muscle regulatory factor MRF4 during somite and skeletal myofiber development. Developmental Biology. 147: 144-56. PMID 1715299 DOI: 10.1016/S0012-1606(05)80014-4  0.498
1990 Enkemann SA, Konieczny SF, Taparowsky EJ. Adenovirus 5 E1A represses muscle-specific enhancers and inhibits expression of the myogenic regulatory factor genes, MyoD1 and myogenin. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 1: 375-82. PMID 2177635  0.501
1990 Yutzey KE, Rhodes SJ, Konieczny SF. Differential trans activation associated with the muscle regulatory factors MyoD1, myogenin, and MRF4. Molecular and Cellular Biology. 10: 3934-44. PMID 1695319 DOI: 10.1128/Mcb.10.8.3934  0.764
1989 Vaidya TB, Rhodes SJ, Taparowsky EJ, Konieczny SF. Fibroblast growth factor and transforming growth factor beta repress transcription of the myogenic regulatory gene MyoD1. Molecular and Cellular Biology. 9: 3576-9. PMID 2797000 DOI: 10.1128/Mcb.9.8.3576  0.43
1989 Yutzey KE, Kline RL, Konieczny SF. An internal regulatory element controls troponin I gene expression. Molecular and Cellular Biology. 9: 1397-405. PMID 2725509 DOI: 10.1128/Mcb.9.4.1397  0.75
1989 Konieczny SF, Drobes BL, Menke SL, Taparowsky EJ. Inhibition of myogenic differentiation by the H-ras oncogene is associated with the down regulation of the MyoD1 gene. Oncogene. 4: 473-81. PMID 2654809  0.393
1989 Rhodes SJ, Konieczny SF. Identification of MRF4: a new member of the muscle regulatory factor gene family. Genes & Development. 3: 2050-61. PMID 2560751 DOI: 10.1101/Gad.3.12B.2050  0.54
1988 Pinney DF, Pearson-White SH, Konieczny SF, Latham KE, Emerson CP. Myogenic lineage determination and differentiation: evidence for a regulatory gene pathway. Cell. 53: 781-93. PMID 3286015 DOI: 10.1016/0092-8674(88)90095-5  0.532
1988 Bucher EA, Maisonpierre PC, Konieczny SF, Emerson CP. Expression of the troponin complex genes: transcriptional coactivation during myoblast differentiation and independent control in heart and skeletal muscles. Molecular and Cellular Biology. 8: 4134-42. PMID 3185544 DOI: 10.1128/Mcb.8.10.4134  0.48
1987 Konieczny SF, Emerson CP. Complex regulation of the muscle-specific contractile protein (troponin I) gene. Molecular and Cellular Biology. 7: 3065-75. PMID 3670306 DOI: 10.1128/Mcb.7.9.3065  0.527
1985 Konieczny SF, Emerson CP. Differentiation, not determination, regulates muscle gene activation: transfection of troponin I genes into multipotential and muscle lineages of 10T1/2 cells. Molecular and Cellular Biology. 5: 2423-32. PMID 2426582 DOI: 10.1128/Mcb.5.9.2423  0.519
1984 Konieczny SF, Emerson CP. 5-Azacytidine induction of stable mesodermal stem cell lineages from 10T1/2 cells: evidence for regulatory genes controlling determination. Cell. 38: 791-800. PMID 6207933 DOI: 10.1016/0092-8674(84)90274-5  0.519
1983 Konieczny SF, Coleman JR. Analysis of myogenesis by somatic cell hybridization: III. Myogenic competence of hybrids derived from rat L6 myoblasts and mouse primary fibroblasts and myoblasts. Somatic Cell Genetics. 9: 25-42. PMID 6836450 DOI: 10.1007/Bf01544046  0.667
1983 Konieczny SF, Lawrence JB, Coleman JR. Analysis of muscle protein expression in polyethylene glycol-induced chicken: rat myoblast heterokaryons. The Journal of Cell Biology. 97: 1348-55. PMID 6630288 DOI: 10.1083/Jcb.97.5.1348  0.711
1982 Lawrence JB, Konieczny SF, Shaffer M, Coleman AW, Coleman JR. Analysis of myogenesis by somatic cell hybridization. I. Myogenic competence of homotypic hybrids derived from rat L6 myoblasts. Experimental Cell Research. 142: 261-72. PMID 7173324 DOI: 10.1016/0014-4827(82)90367-6  0.707
1982 Konieczny SF, McKay J, Coleman JR. Isolation and characterization of terminally differentiated chicken and rat skeletal muscle myoblasts. Developmental Biology. 91: 11-26. PMID 7095255 DOI: 10.1016/0012-1606(82)90003-3  0.715
1982 Konieczny SF, Coleman JR. Analysis of the expression of chicken and rat gene products in myoblast x myoblast cell hybrids. Experimental Cell Research. 142: 247-60. PMID 6756942 DOI: 10.1016/0014-4827(82)90366-4  0.726
1981 Dexter DL, Konieczny SF, Lawrence JB, Shaffer M, Mitchell P, Coleman JR. Induction by butyrate of differentiated properties in cloned murine rhabdomyosarcoma cells. Differentiation; Research in Biological Diversity. 18: 115-22. PMID 7215726 DOI: 10.1111/J.1432-0436.1981.Tb01111.X  0.728
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