Alex Sevy - Publications

Affiliations: 
2014-2018 Chemical and Physical Biology Vanderbilt University School of Medicine, Nashville, TN, United States 

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Schoeder CT, Schmitz S, Adolf-Bryfogle J, Sevy AM, Finn JA, Sauer MF, Bozhanova NG, Mueller BK, Sangha AK, Bonet J, Sheehan JH, Kuenze G, Marlow B, Smith ST, Woods H, et al. Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design. Biochemistry. PMID 33705117 DOI: 10.1021/acs.biochem.0c00912  0.68
2020 Sevy AM, Chen MT, Castor M, Sylvia T, Krishnamurthy H, Ishchenko A, Hsieh CM. Structure- and sequence-based design of synthetic single-domain antibody libraries. Protein Engineering, Design & Selection : Peds. PMID 33341882 DOI: 10.1093/protein/gzaa028  0.381
2020 Bozhanova NG, Sangha AK, Sevy AM, Gilchuk P, Huang K, Nargi RS, Reidy JX, Trivette A, Carnahan RH, Bukreyev A, Crowe JE, Meiler J. Discovery of Marburg virus neutralizing antibodies from virus-naïve human antibody repertoires using large-scale structural predictions. Proceedings of the National Academy of Sciences of the United States of America. PMID 33229516 DOI: 10.1073/pnas.1922654117  0.787
2020 Finn JA, Dong J, Sevy AM, Parrish E, Gilchuk I, Nargi R, Scarlett-Jones M, Reichard W, Bombardi R, Voss TG, Meiler J, Crowe JE. Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring. Structure (London, England : 1993). PMID 32783953 DOI: 10.1016/J.Str.2020.07.012  0.761
2020 Sevy AM, Gilchuk IM, Brown BP, Bozhanova NG, Nargi R, Jensen M, Meiler J, Crowe JE. Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants. Structure (London, England : 1993). PMID 32610044 DOI: 10.1016/J.Str.2020.04.005  0.787
2020 Leman JK, Weitzner BD, Lewis SM, Adolf-Bryfogle J, Alam N, Alford RF, Aprahamian M, Baker D, Barlow KA, Barth P, Basanta B, Bender BJ, Blacklock K, Bonet J, Boyken SE, ... ... Sevy AM, et al. Macromolecular modeling and design in Rosetta: recent methods and frameworks. Nature Methods. PMID 32483333 DOI: 10.1038/S41592-020-0848-2  0.763
2020 Sauer MF, Sevy AM, Crowe JE, Meiler J. Multi-state design of flexible proteins predicts sequences optimal for conformational change. Plos Computational Biology. 16: e1007339. PMID 32032348 DOI: 10.1371/Journal.Pcbi.1007339  0.762
2019 Soto C, Bombardi RG, Branchizio A, Kose N, Matta P, Sevy AM, Sinkovits RS, Gilchuk P, Finn JA, Crowe JE. High frequency of shared clonotypes in human B cell receptor repertoires. Nature. 566: 398-402. PMID 30760926 DOI: 10.1038/S41586-019-0934-8  0.72
2019 Sevy AM, Wu NC, Gilchuk IM, Parrish EH, Burger S, Yousif D, Nagel MBM, Schey KL, Wilson IA, Crowe JE, Meiler J. Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 30642961 DOI: 10.1073/pnas.1806004116  0.809
2018 Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, ... ... Sevy AM, et al. Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. Immunity. PMID 30029854 DOI: 10.1016/J.Immuni.2018.06.018  0.728
2018 Sevy AM, Panda S, Crowe JE, Meiler J, Vorobeychik Y. Integrating linear optimization with structural modeling to increase HIV neutralization breadth. Plos Computational Biology. 14: e1005999. PMID 29451898 DOI: 10.1371/Journal.Pcbi.1005999  0.426
2016 Mousa JJ, Sauer MF, Sevy AM, Finn JA, Bates JT, Alvarado G, King HG, Loerinc LB, Fong RH, Doranz BJ, Correia BE, Kalyuzhniy O, Wen X, Jardetzky TS, Schief WR, et al. Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791117 DOI: 10.1073/Pnas.1609449113  0.687
2016 Bender BJ, Cisneros A, Duran AM, Finn JA, Fu D, Lokits AD, Mueller BK, Sangha AK, Sauer MF, Sevy AM, Sliwoski G, Sheehan JH, DiMaio F, Meiler J, Moretti R. Protocols for Molecular Modeling with Rosetta3 and RosettaScripts. Biochemistry. PMID 27490953 DOI: 10.1021/Acs.Biochem.6B00444  0.632
2015 Sevy AM, Jacobs TM, Crowe JE, Meiler J. Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences. Plos Computational Biology. 11: e1004300. PMID 26147100 DOI: 10.1371/Journal.Pcbi.1004300  0.313
2014 Sevy AM, Meiler J. Antibodies: Computer-Aided Prediction of Structure and Design of Function. Microbiology Spectrum. 2. PMID 26104439 DOI: 10.1128/Microbiolspec.Aid-0024-2014  0.483
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