| Year |
Citation |
Score |
| 2022 |
Margaryan H, Evangelopoulos DD, Muraro Wildner L, McHugh TD. Pre-Clinical Tools for Predicting Drug Efficacy in Treatment of Tuberculosis. Microorganisms. 10. PMID 35336089 DOI: 10.3390/microorganisms10030514 |
0.316 |
|
| 2022 |
Frederickson M, Selvam IR, Evangelopoulos D, McLean KJ, Katariya MM, Tunnicliffe RB, Campbell B, Kavanagh ME, Charoensutthivarakul S, Blankley RT, Levy CW, de Carvalho LPS, Leys D, Munro AW, Coyne AG, et al. A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen). European Journal of Medicinal Chemistry. 230: 114105. PMID 35065413 DOI: 10.1016/j.ejmech.2022.114105 |
0.308 |
|
| 2021 |
Chetty S, Armstrong T, Sharma Kharkwal S, Drewe WC, De Matteis CI, Evangelopoulos D, Bhakta S, Thomas NR. New InhA Inhibitors Based on Expanded Triclosan and -Triclosan Analogues to Develop a New Treatment for Tuberculosis. Pharmaceuticals (Basel, Switzerland). 14. PMID 33919737 DOI: 10.3390/ph14040361 |
0.381 |
|
| 2020 |
Maitra A, Evangelopoulos D, Chrzastek A, Martin LT, Hanrath A, Chapman E, Hailes HC, Lipman M, McHugh TD, Waddell SJ, Bhakta S. Carprofen elicits pleiotropic mechanisms of bactericidal action with the potential to reverse antimicrobial drug resistance in tuberculosis. The Journal of Antimicrobial Chemotherapy. PMID 32790867 DOI: 10.1093/Jac/Dkaa307 |
0.463 |
|
| 2020 |
Fenaroli F, Robertson JD, Scarpa E, Gouveia VM, Di Guglielmo C, De Pace C, Elks PM, Poma A, Evangelopoulos D, Ortiz Canseco J, Marriott HM, Dockrell DH, Foster S, McHugh TD, Renshaw SA, et al. Polymersomes Eradicating Intracellular Bacteria. Acs Nano. PMID 32515944 DOI: 10.1021/Acsnano.0C01870 |
0.428 |
|
| 2018 |
Danquah CA, Kakagianni E, Khondkar P, Maitra A, Rahman M, Evangelopoulos D, McHugh TD, Stapleton P, Malkinson J, Bhakta S, Gibbons S. Analogues of Disulfides from Allium stipitatum Demonstrate Potent Anti-tubercular Activities through Drug Efflux Pump and Biofilm Inhibition. Scientific Reports. 8: 1150. PMID 29348586 DOI: 10.1038/s41598-017-18948-w |
0.409 |
|
| 2017 |
de Knegt GJ, Dickinson L, Pertinez H, Evangelopoulos D, McHugh TD, Bakker-Woudenberg IAJM, Davies GR, de Steenwinkel JEM. Assessment of treatment response by colony forming units, time to culture positivity and the molecular bacterial load assay compared in a mouse tuberculosis model. Tuberculosis (Edinburgh, Scotland). 105: 113-118. PMID 28610782 DOI: 10.1016/J.Tube.2017.05.002 |
0.336 |
|
| 2017 |
Ryan A, Polycarpou E, Lack NA, Evangelopoulos D, Sieg C, Halman A, Bhakta S, Eleftheriadou O, McHugh TD, Keany S, Lowe ED, Ballet R, Abuhammad A, Jacobs WR, Ciulli A, et al. Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach. British Journal of Pharmacology. PMID 28380256 DOI: 10.1111/Bph.13810 |
0.474 |
|
| 2017 |
Evangelopoulos D, Whittaker E, Honeyborne I, McHugh TD, Klein N, Shingadia D. Pediatric tuberculosis-human immunodeficiency virus co-infection in the United Kingdom highlights the need for better therapy monitoring tools: a case report. Journal of Medical Case Reports. 11: 52. PMID 28236807 DOI: 10.1186/S13256-017-1222-6 |
0.356 |
|
| 2016 |
Sabiiti W, Mtafya B, Kuchaka D, Azam K, Viegas S, Mdolo A, Farmer EC, Khonga M, Evangelopoulos D, Honeyborne I, Rachow A, Heinrich N, Ntinginya NE, Bhatt N, Davies GR, et al. Optimising molecular diagnostic capacity for effective control of tuberculosis in high-burden settings. The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. 20: 1004-9. PMID 27393531 DOI: 10.5588/Ijtld.15.0951 |
0.381 |
|
| 2016 |
Brucoli F, Guzman JD, Basher MA, Evangelopoulos D, McMahon E, Munshi T, McHugh TD, Fox KR, Bhakta S. DNA sequence-selective C8-linked pyrrolobenzodiazepine-heterocyclic polyamide conjugates show anti-tubercular-specific activities. The Journal of Antibiotics. PMID 27168314 DOI: 10.1038/Ja.2016.43 |
0.378 |
|
| 2016 |
Maitra A, Bates S, Shaik M, Evangelopoulos D, Abubakar I, McHugh TD, Lipman M, Bhakta S. Repurposing drugs for treatment of tuberculosis: a role for non-steroidal anti-inflammatory drugs. British Medical Bulletin. PMID 27151954 DOI: 10.1093/Bmb/Ldw019 |
0.429 |
|
| 2016 |
Honeyborne I, McHugh TD, Kuittinen I, Cichonska A, Evangelopoulos D, Ronacher K, van Helden PD, Gillespie SH, Fernandez-Reyes D, Walzl G, Rousu J, Butcher PD, Waddell SJ. Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy. Bmc Medicine. 14: 68. PMID 27055815 DOI: 10.1186/S12916-016-0609-3 |
0.387 |
|
| 2016 |
Bhakta S, Scalacci N, Maitra A, Brown AK, Dasugari S, Evangelopoulos D, McHugh TD, Mortazavi PN, Twist A, Petricci E, Manetti F, Castagnolo D. Design and synthesis of 1-((1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N'-((E)-3,7-dimethyl-octa-2,6-dienyl)-ethane-1,2-diamine (SQ109) pyrrole hybrid derivatives: discovery of potent anti-tubercular agents effective against multi-drug resistant mycobacteria. Journal of Medicinal Chemistry. PMID 26907951 DOI: 10.1021/Acs.Jmedchem.6B00031 |
0.418 |
|
| 2015 |
Evangelopoulos D, da Fonseca JD, Waddell SJ. Understanding anti-tuberculosis drug efficacy: rethinking bacterial populations and how we model them. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. 32: 76-80. PMID 25809760 DOI: 10.1016/J.Ijid.2014.11.028 |
0.469 |
|
| 2015 |
Evangelopoulos D, McHugh TD. Improving the Tuberculosis Drug Development Pipeline Chemical Biology and Drug Design. 86: 951-960. PMID 25772393 DOI: 10.1111/Cbdd.12549 |
0.453 |
|
| 2015 |
Honeyborne I, Lipman MC, Eckold C, Evangelopoulos D, Gillespie SH, Pym A, McHugh TD. Effective anti-tuberculosis therapy correlates with plasma small RNA. The European Respiratory Journal. 45: 1741-4. PMID 25745052 DOI: 10.1183/09031936.00221214 |
0.316 |
|
| 2015 |
Guzman JD, Pesnot T, Barrera DA, Davies HM, McMahon E, Evangelopoulos D, Mortazavi PN, Munshi T, Maitra A, Lamming ED, Angell R, Gershater MC, Redmond JM, Needham D, Ward JM, et al. Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase. The Journal of Antimicrobial Chemotherapy. 70: 1691-703. PMID 25656411 DOI: 10.1093/Jac/Dkv010 |
0.464 |
|
| 2015 |
Hochfellner C, Evangelopoulos D, Zloh M, Wube A, Guzman JD, McHugh TD, Kunert O, Bhakta S, Bucar F. Antagonistic effects of indoloquinazoline alkaloids on antimycobacterial activity of evocarpine. Journal of Applied Microbiology. 118: 864-72. PMID 25604161 DOI: 10.1111/Jam.12753 |
0.41 |
|
| 2014 |
Zhao J, Evangelopoulos D, Bhakta S, Gray AI, Seidel V. Antitubercular activity of Arctium lappa and Tussilago farfara extracts and constituents. Journal of Ethnopharmacology. 155: 796-800. PMID 24955560 DOI: 10.1016/J.Jep.2014.06.034 |
0.365 |
|
| 2014 |
McGuigan C, Derudas M, Gonczy B, Hinsinger K, Kandil S, Pertusati F, Serpi M, Snoeck R, Andrei G, Balzarini J, McHugh TD, Maitra A, Akorli E, Evangelopoulos D, Bhakta S. ProTides of N-(3-(5-(2'-deoxyuridine))prop-2-ynyl)octanamide as potential anti-tubercular and anti-viral agents. Bioorganic & Medicinal Chemistry. 22: 2816-24. PMID 24690527 DOI: 10.1016/J.Bmc.2014.02.056 |
0.424 |
|
| 2014 |
Guzman JD, Mortazavi PN, Munshi T, Evangelopoulos D, McHugh TD, Gibbons S, Malkinson J, Bhakta S. 2-Hydroxy-substituted cinnamic acids and acetanilides are selective growth inhibitors of Mycobacterium tuberculosis Medchemcomm. 5: 47-50. DOI: 10.1039/C3Md00251A |
0.48 |
|
| 2013 |
Shiu WK, Malkinson JP, Rahman MM, Curry J, Stapleton P, Gunaratnam M, Neidle S, Mushtaq S, Warner M, Livermore DM, Evangelopoulos D, Basavannacharya C, Bhakta S, Schindler BD, Seo SM, et al. A new plant-derived antibacterial is an inhibitor of efflux pumps in Staphylococcus aureus. International Journal of Antimicrobial Agents. 42: 513-8. PMID 24119569 DOI: 10.1016/J.Ijantimicag.2013.08.007 |
0.374 |
|
| 2013 |
Guzman JD, Evangelopoulos D, Gupta A, Birchall K, Mwaigwisya S, Saxty B, McHugh TD, Gibbons S, Malkinson J, Bhakta S. Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay. Bmj Open. 3. PMID 23794563 DOI: 10.1136/Bmjopen-2013-002672 |
0.486 |
|
| 2013 |
Munshi T, Gupta A, Evangelopoulos D, Guzman JD, Gibbons S, Keep NH, Bhakta S. Characterisation of ATP-dependent Mur ligases involved in the biogenesis of cell wall peptidoglycan in Mycobacterium tuberculosis. Plos One. 8: e60143. PMID 23555903 DOI: 10.1371/Journal.Pone.0060143 |
0.392 |
|
| 2013 |
Guzman JD, Evangelopoulos D, Gupta A, Prieto JM, Gibbons S, Bhakta S. Antimycobacterials from lovage root (Ligusticum officinale Koch). Phytotherapy Research : Ptr. 27: 993-8. PMID 22899555 DOI: 10.1002/Ptr.4823 |
0.388 |
|
| 2012 |
Kottakota SK, Evangelopoulos D, Alnimr A, Bhakta S, McHugh TD, Gray M, Groundwater PW, Marrs EC, Perry JD, Spilling CD, Harburn JJ. Synthesis and biological evaluation of purpurealidin E-derived marine sponge metabolites: aplysamine-2, aplyzanzine A, and suberedamines A and B. Journal of Natural Products. 75: 1090-101. PMID 22620987 DOI: 10.1021/Np300102Z |
0.401 |
|
| 2012 |
Osman K, Evangelopoulos D, Basavannacharya C, Gupta A, McHugh TD, Bhakta S, Gibbons S. An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis. International Journal of Antimicrobial Agents. 39: 124-9. PMID 22079533 DOI: 10.1016/J.Ijantimicag.2011.09.018 |
0.425 |
|
| 2012 |
Markarian SA, Evangelopoulos D, Harutyunyan LR, Pepoyan EK, Guzman JD, McHugh TD, Bhakta S. The properties of solutions of isoniazid in water and dimethylsulfoxide Journal of Solution Chemistry. 41: 1462-1476. DOI: 10.1007/S10953-012-9883-7 |
0.307 |
|
| 2011 |
Evangelopoulos D, Cronin N, Daviter T, Sim E, Keep NH, Bhakta S. Characterization of an oxidoreductase from the arylamine N-acetyltransferase operon in Mycobacterium smegmatis. The Febs Journal. 278: 4824-32. PMID 21972977 DOI: 10.1111/J.1742-4658.2011.08382.X |
0.32 |
|
| 2011 |
Guzman JD, Wube A, Evangelopoulos D, Gupta A, Hüfner A, Basavannacharya C, Rahman MM, Thomaschitz C, Bauer R, McHugh TD, Nobeli I, Prieto JM, Gibbons S, Bucar F, Bhakta S. Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics. The Journal of Antimicrobial Chemotherapy. 66: 1766-72. PMID 21622974 DOI: 10.1093/Jac/Dkr203 |
0.476 |
|
| 2010 |
Guzman JD, Gupta A, Evangelopoulos D, Basavannacharya C, Pabon LC, Plazas EA, Muñoz DR, Delgado WA, Cuca LE, Ribon W, Gibbons S, Bhakta S. Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. The Journal of Antimicrobial Chemotherapy. 65: 2101-7. PMID 20719764 DOI: 10.1093/Jac/Dkq313 |
0.5 |
|
| 2010 |
Evangelopoulos D, Bhakta S. Rapid methods for testing inhibitors of mycobacterial growth. Methods in Molecular Biology (Clifton, N.J.). 642: 193-201. PMID 20401596 DOI: 10.1007/978-1-60327-279-7_15 |
0.431 |
|
| 2009 |
O'Donnell G, Poeschl R, Zimhony O, Gunaratnam M, Moreira JB, Neidle S, Evangelopoulos D, Bhakta S, Malkinson JP, Boshoff HI, Lenaerts A, Gibbons S. Bioactive pyridine-N-oxide disulfides from Allium stipitatum. Journal of Natural Products. 72: 360-5. PMID 19093848 DOI: 10.1021/Np800572R |
0.369 |
|
| 2009 |
Lack NA, Kawamura A, Fullam E, Laurieri N, Beard S, Russell AJ, Evangelopoulos D, Westwood I, Sim E. Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis. The Biochemical Journal. 418: 369-78. PMID 19014350 DOI: 10.1042/Bj20082011 |
0.396 |
|
| 2008 |
Sim E, Sandy J, Evangelopoulos D, Fullam E, Bhakta S, Westwood I, Krylova A, Lack N, Noble M. Arylamine N-acetyltransferases in mycobacteria. Current Drug Metabolism. 9: 510-9. PMID 18680471 DOI: 10.2174/138920008784892100 |
0.357 |
|
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