| Year |
Citation |
Score |
| 2024 |
Li X, Zhang X, Wen X, Zhang D, Qu C, Miao X, Zhang W, Zhang R, Liu G, Xiao P, Sun JP, Gong W. Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Reports. 43: 113893. PMID 38446662 DOI: 10.1016/j.celrep.2024.113893 |
0.367 |
|
| 2024 |
Mao C, Zhao RJ, Dong YJ, Gao M, Chen LN, Zhang C, Xiao P, Guo J, Qin J, Shen DD, Ji SY, Zang SK, Zhang H, Wang WW, Shen Q, ... Sun JP, et al. Conformational transitions and activation of the adhesion receptor CD97. Molecular Cell. PMID 38215752 DOI: 10.1016/j.molcel.2023.12.020 |
0.52 |
|
| 2023 |
Shang P, Rong N, Jiang JJ, Cheng J, Zhang MH, Kang D, Qi L, Guo L, Yang GM, Liu Q, Zhou Z, Li XB, Zhu KK, Meng QB, Han X, ... ... Sun JP, et al. Structural and signaling mechanisms of TAAR1 enabled preferential agonist design. Cell. PMID 37963465 DOI: 10.1016/j.cell.2023.10.014 |
0.379 |
|
| 2023 |
Yang Z, Wang JY, Yang F, Zhu KK, Wang GP, Guan Y, Ning SL, Lu Y, Li Y, Zhang C, Zheng Y, Zhou SH, Wang XW, Wang MW, Xiao P, ... ... Sun JP, et al. Structure of GPR101-Gs enables identification of ligands with rejuvenating potential. Nature Chemical Biology. PMID 37945893 DOI: 10.1038/s41589-023-01456-6 |
0.561 |
|
| 2023 |
Xu Z, Guo L, Yu J, Shen S, Wu C, Zhang W, Zhao C, Deng Y, Tian X, Feng Y, Hou H, Su L, Wang H, Guo S, Wang H, ... ... Sun JP, et al. Ligand recognition and G protein coupling of trace amine receptor TAAR1. Nature. PMID 37935376 DOI: 10.1038/s41586-023-06804-z |
0.424 |
|
| 2023 |
Guo L, Zhang Y, Fang G, Tie L, Zhuang Y, Xue C, Liu Q, Zhang M, Zhu K, You C, Xu P, Yuan Q, Zhang C, Liu L, Rong N, ... ... Sun JP, et al. Ligand recognition and G protein coupling of the human itch receptor MRGPRX1. Nature Communications. 14: 5004. PMID 37591889 DOI: 10.1038/s41467-023-40705-z |
0.427 |
|
| 2023 |
Huang SM, Xiong MY, Liu L, Mu J, Wang MW, Jia YL, Cai K, Tie L, Zhang C, Cao S, Wen X, Wang JL, Guo SC, Li Y, Qu CX, ... ... Sun JP, et al. Single hormone or synthetic agonist induces G/G coupling selectivity of EP receptors via distinct binding modes and propagating paths. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216329120. PMID 37478163 DOI: 10.1073/pnas.2216329120 |
0.811 |
|
| 2023 |
Pei Y, Wen X, Guo SC, Yang ZS, Zhang R, Xiao P, Sun JP. Structural insight into the selective agonist ST1936 binding of serotonin receptor 5-HT6. Biochemical and Biophysical Research Communications. 671: 327-334. PMID 37327704 DOI: 10.1016/j.bbrc.2023.05.126 |
0.508 |
|
| 2023 |
Guo L, Cheng J, Lian S, Liu Q, Lu Y, Zheng Y, Zhu K, Zhang M, Kong Y, Zhang C, Rong N, Zhuang Y, Fang G, Jiang J, Zhang T, ... ... Sun JP, et al. Structural basis of amine odorant perception by a mammal olfactory receptor. Nature. PMID 37225986 DOI: 10.1038/s41586-023-06106-4 |
0.387 |
|
| 2023 |
Guan Y, Du HB, Yang Z, Wang YZ, Ren R, Liu WW, Zhang C, Zhang JH, An WT, Li NN, Zeng XX, Li J, Sun YX, Wang YF, Yang F, ... ... Sun JP, et al. Deafness-Associated ADGRV1 Mutation Impairs USH2A Stability through Improper Phosphorylation of WHRN and WDSUB1 Recruitment. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2205993. PMID 37066759 DOI: 10.1002/advs.202205993 |
0.803 |
|
| 2023 |
Mao C, Xiao P, Tao XN, Qin J, He QT, Zhang C, Guo SC, Du YQ, Chen LN, Shen DD, Yang ZS, Zhang HQ, Huang SM, He YH, Cheng J, ... ... Sun JP, et al. Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science (New York, N.Y.). eadd6220. PMID 36862765 DOI: 10.1126/science.add6220 |
0.797 |
|
| 2022 |
Lin H, Xiao P, Bu RQ, Guo S, Yang Z, Yuan D, Zhu ZL, Zhang CX, He QT, Zhang C, Ping YQ, Zhao RJ, Ma CS, Liu CH, Zhang XN, ... ... Sun JP, et al. Structures of the ADGRG2-G complex in apo and ligand-bound forms. Nature Chemical Biology. PMID 35982227 DOI: 10.1038/s41589-022-01084-6 |
0.76 |
|
| 2022 |
Ma L, Yang F, Wu X, Mao C, Guo L, Miao T, Zang SK, Jiang X, Shen DD, Wei T, Zhou H, Wei Q, Li S, Shu Q, Feng S, ... ... Sun JP, et al. Structural basis and molecular mechanism of biased GPBAR signaling in regulating NSCLC cell growth via YAP activity. Proceedings of the National Academy of Sciences of the United States of America. 119: e2117054119. PMID 35858343 DOI: 10.1073/pnas.2117054119 |
0.403 |
|
| 2022 |
Du YQ, Sha XY, Cheng J, Wang J, Lin JY, An WT, Pan W, Zhang LJ, Tao XN, Xu Y, Jia YL, Yang Z, Xiao P, Liu M, Sun JP, et al. Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents. Diabetes. PMID 35472681 DOI: 10.2337/db21-0794 |
0.784 |
|
| 2022 |
Ping YQ, Xiao P, Yang F, Zhao RJ, Guo SC, Yan X, Wu X, Zhang C, Lu Y, Zhao F, Zhou F, Xi YT, Yin W, Liu FZ, He DF, ... ... Sun JP, et al. Structural basis for the tethered peptide activation of adhesion GPCRs. Nature. PMID 35418678 DOI: 10.1038/s41586-022-04619-y |
0.764 |
|
| 2022 |
Xiao P, Guo S, Wen X, He QT, Lin H, Huang SM, Gou L, Zhang C, Yang Z, Zhong YN, Yang CC, Li Y, Gong Z, Tao XN, Yang ZS, ... ... Sun JP, et al. Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature. PMID 35418677 DOI: 10.1038/s41586-022-04590-8 |
0.814 |
|
| 2022 |
An W, Lin H, Ma L, Zhang C, Zheng Y, Cheng Q, Ma C, Wu X, Zhang Z, Zhong Y, Wang M, He D, Yang Z, Du L, Feng S, ... ... Sun JP, et al. Progesterone activates GPR126 to promote breast cancer development via the Gi pathway. Proceedings of the National Academy of Sciences of the United States of America. 119: e2117004119. PMID 35394864 DOI: 10.1073/pnas.2117004119 |
0.789 |
|
| 2022 |
Lu R, Yan X, Fang G, Zhuang Y, Guo L, Zhang C, Wu X, Xiao P, Cao Y, Yang F, Yu X, Sun JP, Zhou JY. A molecular mechanism of UDCA engagement with GPBAR and subsequent G protein interaction revealed by scattered alanine scanning. Biochemical and Biophysical Research Communications. 600: 14-21. PMID 35182970 DOI: 10.1016/j.bbrc.2022.02.030 |
0.535 |
|
| 2022 |
Cheng J, Yang Z, Ge XY, Gao MX, Meng R, Xu X, Zhang YQ, Li RZ, Lin JY, Tian ZM, Wang J, Ning SL, Xu YF, Yang F, Gu JK, ... Sun JP, et al. Autonomous sensing of the insulin peptide by an olfactory G protein-coupled receptor modulates glucose metabolism. Cell Metabolism. 34: 240-255.e10. PMID 35108512 DOI: 10.1016/j.cmet.2021.12.022 |
0.647 |
|
| 2021 |
Yang F, Guo L, Li Y, Wang G, Wang J, Zhang C, Fang GX, Chen X, Liu L, Yan X, Liu Q, Qu C, Xu Y, Xiao P, Zhu Z, ... ... Sun JP, et al. Structure, function and pharmacology of human itch receptor complexes. Nature. PMID 34789875 DOI: 10.1038/s41586-021-04077-y |
0.576 |
|
| 2021 |
Qu C, Park JY, Yun MW, He QT, Yang F, Kim K, Ham D, Li RR, Iverson TM, Gurevich VV, Sun JP, Chung KY. Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34507982 DOI: 10.1073/pnas.2026491118 |
0.395 |
|
| 2021 |
Lin JY, Yang Z, Yang C, Du JX, Yang F, Cheng J, Pan W, Zhang SJ, Yan X, Wang J, Wang J, Tie L, Yu X, Chen X, Sun JP. An ionic lock and a hydrophobic zipper mediate the coupling between an insect pheromone receptor BmOR3 and downstream effectors. The Journal of Biological Chemistry. 101160. PMID 34480896 DOI: 10.1016/j.jbc.2021.101160 |
0.432 |
|
| 2021 |
Zhang H, Chen LN, Yang D, Mao C, Shen Q, Feng W, Shen DD, Dai A, Xie S, Zhou Y, Qin J, Sun JP, Scharf DH, Hou T, Zhou T, et al. Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Research. PMID 34433901 DOI: 10.1038/s41422-021-00552-3 |
0.365 |
|
| 2021 |
Han MJ, He QT, Yang M, Chen C, Yao Y, Liu X, Wang Y, Zhu ZL, Zhu KK, Qu C, Yang F, Hu C, Guo X, Zhang D, Chen C, ... Sun JP, et al. Single-molecule FRET and conformational analysis of beta-arrestin-1 through genetic code expansion and a Se-click reaction. Chemical Science. 12: 9114-9123. PMID 34276941 DOI: 10.1039/d1sc02653d |
0.36 |
|
| 2021 |
He QT, Xiao P, Huang SM, Jia YL, Zhu ZL, Lin JY, Yang F, Tao XN, Zhao RJ, Gao FY, Niu XG, Xiao KH, Wang J, Jin C, Sun JP, et al. Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2. Nature Communications. 12: 2396. PMID 33888704 DOI: 10.1038/s41467-021-22731-x |
0.817 |
|
| 2021 |
Qu C, Mao C, Xiao P, Shen Q, Zhong YN, Yang F, Shen DD, Tao X, Zhang H, Yan X, Zhao RJ, He J, Guan Y, Zhang C, Hou G, ... ... Sun JP, et al. Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E receptor EP2 subtype. Science Advances. 7. PMID 33811074 DOI: 10.1126/sciadv.abf1268 |
0.586 |
|
| 2021 |
Xu YF, Chen X, Yang Z, Xiao P, Liu CH, Li KS, Yang XZ, Wang YJ, Zhu ZL, Xu ZG, Zhang S, Wang C, Song YC, Zhao WD, Wang CH, ... ... Sun JP, et al. PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Reports. e52141. PMID 33764618 DOI: 10.15252/embr.202052141 |
0.776 |
|
| 2021 |
Xiao P, Yan W, Gou L, Zhong YN, Kong L, Wu C, Wen X, Yuan Y, Cao S, Qu C, Yang X, Yang CC, Xia A, Hu Z, Zhang Q, ... ... Sun JP, et al. Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes. Cell. PMID 33571432 DOI: 10.1016/j.cell.2021.01.028 |
0.754 |
|
| 2021 |
Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, ... ... Sun JP, et al. Structures of the glucocorticoid-bound adhesion receptor GPR97-G complex. Nature. PMID 33408414 DOI: 10.1038/s41586-020-03083-w |
0.817 |
|
| 2020 |
Lin JY, Cheng J, Du YQ, Pan W, Zhang Z, Wang J, An J, Yang F, Xu YF, Lin H, An WT, Wang J, Yang Z, Chai RJ, Sha XY, ... ... Sun JP, et al. In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals. Cell Discovery. 6: 20. PMID 33824290 DOI: 10.1038/s41421-020-0159-x |
0.613 |
|
| 2020 |
Sun Y, Zhang D, Ma ML, Lin H, Song Y, Wang J, Ma C, Yu K, An W, Guo S, He D, Yang Z, Xiao P, Hou G, Yu X, ... Sun JP, et al. Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology. The Journal of Biological Chemistry. PMID 33303626 DOI: 10.1074/jbc.RA120.014726 |
0.778 |
|
| 2020 |
Liu Q, He QT, Lyu X, Yang F, Zhu ZL, Xiao P, Yang Z, Zhang F, Yang ZY, Wang XY, Sun P, Wang QW, Qu CX, Gong Z, Lin JY, ... ... Sun JP, et al. DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl H-NMR probe. Nature Communications. 11: 4857. PMID 32978402 DOI: 10.1038/s41467-020-18433-5 |
0.822 |
|
| 2020 |
Zhang D, Wang Y, Lin H, Sun Y, Wang M, Jia Y, Yu X, Jiang H, Xu W, Sun J, Xu Z. Function and therapeutic potential of GPCRs in epididymis. British Journal of Pharmacology. PMID 32901914 DOI: 10.1111/Bph.15252 |
0.707 |
|
| 2020 |
Yang F, Mao C, Guo L, Lin J, Ming Q, Xiao P, Wu X, Shen Q, Guo S, Shen DD, Lu R, Zhang L, Huang S, Ping Y, Zhang C, ... ... Sun JP, et al. Structural basis of GPBAR activation and bile acid recognition. Nature. PMID 32698187 DOI: 10.1038/S41586-020-2569-1 |
0.804 |
|
| 2020 |
Huang S, Xiao P, Sun J. Structural basis of signaling of cannabinoids receptors: paving a way for rational drug design in controling mutiple neurological and immune diseases. Signal Transduction and Targeted Therapy. 5: 127. PMID 32694501 DOI: 10.1038/S41392-020-00240-5 |
0.786 |
|
| 2020 |
Lin JY, Cheng J, Du YQ, Pan W, Zhang Z, Wang J, An J, Yang F, Xu YF, Lin H, An WT, Wang J, Yang Z, Chai RJ, Sha XY, ... ... Sun JP, et al. In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals. Cell Discovery. 6: 20. PMID 32284878 DOI: 10.1038/S41421-020-0159-X |
0.756 |
|
| 2020 |
Zhao S, Guo S, Yang C, Gong Z, Wang Y, Jia Y, Jiang X, Xu L, Shi L, Yu X, Sun J, Zhang Y, Chen X. Cell active and functionally-relevant small-molecule agonists of calcitonin receptor. Bioorganic Chemistry. 96: 103596. PMID 32004895 DOI: 10.1016/J.Bioorg.2020.103596 |
0.418 |
|
| 2019 |
Gong Q, Qin W, Xiao P, Wu X, Li L, Zhang G, Zhang R, Sun J, Yao SQ, Huang W. Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells. Chemical Communications (Cambridge, England). PMID 31690925 DOI: 10.1039/C9Cc07680H |
0.434 |
|
| 2019 |
Huang SM, Yang F, Cai BY, He QT, Liu Q, Qu CX, Han MJ, Kong W, Jia YL, Li F, Yu X, Sun JP, Wang J. A Genetically Encoded Fluorescent Amino Acid for Monitoring Protein Interactions through FRET. Analytical Chemistry. PMID 31670502 DOI: 10.1021/Acs.Analchem.9B03305 |
0.797 |
|
| 2019 |
Park JY, Qu CX, Li RR, Yang F, Yu X, Tian ZM, Shen YM, Cai BY, Yun Y, Sun JP, Chung KY. Structural Mechanism of the Arrestin-3/JNK3 Interaction. Structure (London, England : 1993). PMID 31080119 DOI: 10.1016/J.Str.2019.04.002 |
0.504 |
|
| 2019 |
Li K, Hou X, Li R, Bi W, Yang F, Chen X, Xiao P, Liu T, Lu T, Zhou Y, Tian Z, Shen Y, Zhang Y, Wang J, Fang H, ... Sun J, et al. Identification and structure-function analyses of an allosteric inhibitor of the tyrosine phosphatase PTPN22. The Journal of Biological Chemistry. PMID 30979725 DOI: 10.1074/Jbc.Ra118.007129 |
0.556 |
|
| 2018 |
Rostaminasab Dolatabad M, Guo LL, Xiao P, Zhu Z, He QT, Yang DX, Qu CX, Guo SC, Fu XL, Li RR, Ge L, Hu KJ, Hong-da L, Shen YM, Yu X, ... Sun JP, et al. Crystal structure and catalytic activity of the PPM1K N94K mutant. Journal of Neurochemistry. PMID 30451284 DOI: 10.1111/Jnc.14631 |
0.489 |
|
| 2018 |
Hou X, Rooklin DW, Yang D, Liang X, Li K, Lu J, Wang C, Xiao P, Zhang Y, Sun JP, Fang H. Computational strategy for bound state structure prediction in structure-based virtual screening: a case study of protein tyrosine phosphatase receptor type O inhibitors. Journal of Chemical Information and Modeling. PMID 30299094 DOI: 10.1021/Acs.Jcim.8B00548 |
0.467 |
|
| 2018 |
Yang D, Xiao P, Li Q, Fu X, Pan C, Lu D, Wen S, Xia W, He D, Li H, Fang H, Shen Y, Xu Z, Lin A, Yu X, ... ... Sun J, et al. Allosteric modulation of the catalytic VYD loop in Slingshot by its N-terminal domain underlies both Slingshot autoinhibition and activation. The Journal of Biological Chemistry. PMID 30154244 DOI: 10.1074/Jbc.Ra118.004175 |
0.515 |
|
| 2018 |
Yang F, Xiao P, Qu CX, Liu Q, Wang LY, Liu ZX, He QT, Liu C, Xu JY, Li RR, Li MJ, Li Q, Guo XZ, Yang ZY, He DF, ... ... Sun JP, et al. Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin. Nat Chem Biol. 14: 876-886. PMID 30120361 DOI: 10.1038/s41589-018-0115-3 |
0.42 |
|
| 2018 |
Yang F, Xiao P, Qu CX, Liu Q, Wang LY, Liu ZX, He QT, Liu C, Xu JY, Li RR, Li MJ, Li Q, Guo XZ, Yang ZY, He DF, ... ... Sun JP, et al. Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin. Nature Chemical Biology. PMID 30120361 DOI: 10.1038/S41589-018-0115-3 |
0.655 |
|
| 2018 |
Nair A, Chung HC, Sun T, Tyagi S, Dobrolecki LE, Dominguez-Vidana R, Kurley SJ, Orellana M, Renwick A, Henke DM, Katsonis P, Schmitt E, Chan DW, Li H, Mao S, ... ... Sun J, et al. Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer. Nature Medicine. PMID 29578538 DOI: 10.1038/Nm.4507 |
0.404 |
|
| 2018 |
Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, Lin A, Mo H, Lu YJ, Li MJ, Kong W, ... ... Sun JP, et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility. Elife. 7. PMID 29393851 DOI: 10.7554/Elife.33432 |
0.813 |
|
| 2018 |
Li T, Yu B, Liu Z, Li J, Ma M, Wang Y, Zhu M, Yin H, Wang X, Fu Y, Yu F, Wang X, Fang X, Sun J, Kong W. Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury. Nature Communications. 9: 11. PMID 29296021 DOI: 10.1038/S41467-017-02401-7 |
0.382 |
|
| 2018 |
Zhang D, Sun Y, Ma M, Wang Y, Lin H, Li R, Liang Z, Gao Y, Yang Z, He D, Lin A, Mo H, Lu Y, Li M, Kong W, ... ... Sun J, et al. Author response: Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility Elife. DOI: 10.7554/Elife.33432.051 |
0.781 |
|
| 2017 |
Xu H, Li Q, Liu J, Zhu J, Li L, Wang Z, Zhang Y, Sun Y, Sun J, Wang R, Yi F. β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice. Journal of Molecular Medicine (Berlin, Germany). PMID 29116339 DOI: 10.1007/S00109-017-1606-5 |
0.341 |
|
| 2017 |
Xiao K, Sun J. Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics. Cellular Signalling. PMID 28939107 DOI: 10.1016/J.Cellsig.2017.09.013 |
0.468 |
|
| 2017 |
Li H, Yang D, Ning S, Xu Y, Yang F, Yin R, Feng T, Han S, Guo L, Zhang P, Qu W, Guo R, Song C, Xiao P, Zhou C, ... ... Sun JP, et al. Switching of the substrate specificity of protein tyrosine phosphatase N12 by cyclin-dependent kinase 2 phosphorylation orchestrating 2 oncogenic pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28842430 DOI: 10.1096/Fj.201700418R |
0.552 |
|
| 2017 |
Zhang H, Xiao P, Wong YT, Shen W, Chhabra M, Peltier R, Jiang Y, He Y, He J, Tan Y, Xie Y, Ho D, Lam YW, Sun J, Sun H. Construction of an alkaline phosphatase-specific two-photon probe and its imaging application in living cells and tissues. Biomaterials. 140: 220-229. PMID 28662402 DOI: 10.1016/J.Biomaterials.2017.06.032 |
0.446 |
|
| 2017 |
Li Q, Cui M, Yang F, Li N, Jiang B, Yu Z, Zhang D, Wang Y, Zhu X, Hu H, Li PS, Ning SL, Wang S, Qi H, Song H, ... ... Sun JP, et al. A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions. The Journal of Clinical Investigation. PMID 28604389 DOI: 10.1172/Jci91348 |
0.673 |
|
| 2017 |
Yang Z, Yang F, Zhang D, Liu Z, Lin A, Liu C, Xiao P, Yu X, Sun JP. Phosphorylation of G protein-coupled receptors: from the barcode hypothesis to the flute model. Molecular Pharmacology. PMID 28246190 DOI: 10.1124/Mol.116.107839 |
0.798 |
|
| 2017 |
Cahill TJ, Thomsen AR, Tarrasch JT, Plouffe B, Nguyen AH, Yang F, Huang LY, Kahsai AW, Bassoni DL, Gavino BJ, Lamerdin JE, Triest S, Shukla AK, Berger B, Little J, ... ... Sun JP, et al. Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223524 DOI: 10.1073/Pnas.1701529114 |
0.816 |
|
| 2017 |
Liu CH, Gong Z, Liang ZL, Liu ZX, Yang F, Sun YJ, Ma ML, Wang YJ, Ji CR, Wang YH, Wang MJ, Cui FA, Lin A, Zheng WS, He DF, ... ... Sun JP, et al. Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling. Nature Communications. 8: 14335. PMID 28181498 DOI: 10.1038/Ncomms14335 |
0.823 |
|
| 2016 |
Dong JH, Wang YJ, Cui M, Wang XJ, Zheng WS, Ma ML, Yang F, He DF, Hu QX, Zhang DL, Ning SL, Liu CH, Wang C, Wang Y, Li XY, ... ... Sun JP, et al. Adaptive Activation of a Stress Response Pathway Improves Learning and Memory Through Gs and β-Arrestin-1-Regulated Lactate Metabolism. Biological Psychiatry. PMID 27916196 DOI: 10.1016/J.Biopsych.2016.09.025 |
0.718 |
|
| 2016 |
Ge L, Li KS, Li MM, Xiao P, Hou XB, Chen X, Liu HD, Lin A, Yu X, Ren GJ, Fang H, Sun JP. Identification of a benzo imidazole thiazole derivative as the specific irreversible inhibitor of protein tyrosine phosphatase. Bioorganic & Medicinal Chemistry Letters. PMID 27554446 DOI: 10.1016/J.Bmcl.2016.08.024 |
0.506 |
|
| 2016 |
Li H, Yang F, Liu C, Xiao P, Xu Y, Liang Z, Liu C, Wang H, Wang W, Zheng W, Zhang W, Ma X, He D, Song X, Cui F, ... ... Sun JP, et al. Crystal Structure and Substrate Specificity of PTPN12. Cell Reports. PMID 27134172 DOI: 10.1016/J.Celrep.2016.04.016 |
0.757 |
|
| 2016 |
Sun JP, Meng F, Yang XS, Lee AP, Chen M, Zhang B, Yu CM. Prevalence of atrial septal pouch and risk of ischemic stroke. International Journal of Cardiology. 214: 37-40. PMID 27057971 DOI: 10.1016/J.Ijcard.2016.03.119 |
0.32 |
|
| 2016 |
Sun J, Zhang D, Wang Y, Lin H, Yu X, Xu Z. The Role of G Protein-coupled Receptors in Cochlear Planar Cell Polarity. The International Journal of Biochemistry & Cell Biology. PMID 26921719 DOI: 10.1016/J.Biocel.2016.02.011 |
0.724 |
|
| 2016 |
Yu X, Ning S, Sun J. Biased Signaling of GPCR Regulates Pancreatic Beta Cell Secretion and Survival Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.547 |
0.405 |
|
| 2015 |
Li A, Yang D, Zhu M, Tsai KC, Xiao KH, Yu X, Sun J, Du L. Discovery of novel FFA4 (GPR120) receptor agonists with β-arrestin2-biased characteristics. Future Medicinal Chemistry. PMID 26653412 DOI: 10.4155/Fmc.15.160 |
0.441 |
|
| 2015 |
Liu Y, Xu M, Fan H, Chen M, Wang J, Zhang L, Meng F, Dong Y, Yu CM, Zhang B, Sun JP. Primary cardiac lymphoma: Two rare cases. International Journal of Cardiology. 203: 763-765. PMID 26590890 DOI: 10.1016/J.Ijcard.2015.11.043 |
0.331 |
|
| 2015 |
Li KS, Xiao P, Zhang DL, Hou XB, Ge L, Yang DX, Liu HD, He DF, Chen X, Han KR, Song XY, Yu X, Fang H, Sun JP. Identification of para-Substituted Benzoic Acid Derivatives as Potent Inhibitors of the Protein Phosphatase Slingshot. Chemmedchem. PMID 26553423 DOI: 10.1002/Cmdc.201500454 |
0.713 |
|
| 2015 |
Hou X, Li K, Yu X, Sun JP, Fang H. Protein Flexibility in Docking-Based Virtual Screening: Discovery of Novel Lymphoid-Specific Tyrosine Phosphatase Inhibitors Using Multiple Crystal Structures. Journal of Chemical Information and Modeling. PMID 26360643 DOI: 10.1021/Acs.Jcim.5B00344 |
0.36 |
|
| 2015 |
Yang F, Yu X, Liu C, Qu CX, Gong Z, Liu HD, Li FH, Wang HM, He DF, Yi F, Song C, Tian CL, Xiao KH, Wang JY, Sun JP. Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR. Nature Communications. 6: 8202. PMID 26347956 DOI: 10.1038/Ncomms9202 |
0.535 |
|
| 2015 |
Ning SL, Zheng WS, Su J, Liang N, Li H, Zhang D, Dong JH, Zhang ZK, Cui M, Hu QX, Chen CC, Liu CH, Wang C, Pang Q, Chen Y, ... ... Sun JP, et al. Different downstream signaling of CCKAR regulates distinct functions of CCK in pancreatic β cells. British Journal of Pharmacology. PMID 26248680 DOI: 10.1111/Bph.13271 |
0.759 |
|
| 2015 |
Liua HD, Wang WB, Xu ZG, Liu CH, He DF, Du LP, Li MY, Yu X, Sun JP. FFA4 receptor (GPR120)：A hot target for the development of anti-diabetic therapies. European Journal of Pharmacology. PMID 26123847 DOI: 10.1016/J.Ejphar.2015.06.028 |
0.325 |
|
| 2015 |
Pan C, Tang JY, Xu YF, Xiao P, Liu HD, Wang HA, Wang WB, Meng FG, Yu X, Sun JP. The catalytic role of the M2 metal ion in PP2Cα. Scientific Reports. 5: 8560. PMID 25708299 DOI: 10.1038/Srep08560 |
0.67 |
|
| 2014 |
Xiao P, Wang X, Wang HM, Fu XL, Cui FA, Yu X, Wen SS, Bi WX, Sun JP. The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop. The International Journal of Biochemistry & Cell Biology. 57: 84-95. PMID 25450460 DOI: 10.1016/J.Biocel.2014.10.004 |
0.557 |
|
| 2014 |
Hou X, Li R, Li K, Yu X, Sun JP, Fang H. Fast identification of novel lymphoid tyrosine phosphatase inhibitors using target-ligand interaction-based virtual screening. Journal of Medicinal Chemistry. 57: 9309-22. PMID 25372368 DOI: 10.1021/Jm500692U |
0.32 |
|
| 2014 |
Wang XJ, Zhang DL, Xu ZG, Ma ML, Wang WB, Li LL, Han XL, Huo Y, Yu X, Sun JP. Understanding cadherin EGF LAG seven-pass G-type receptors. Journal of Neurochemistry. 131: 699-711. PMID 25280249 DOI: 10.1111/jnc.12955 |
0.736 |
|
| 2014 |
Wang HM, Xu YF, Ning SL, Yang DX, Li Y, Du YJ, Yang F, Zhang Y, Liang N, Yao W, Zhang LL, Gu LC, Gao CJ, Pang Q, Chen YX, ... ... Sun JP, et al. The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes. Cell Research. 24: 1067-90. PMID 25081058 DOI: 10.1038/Cr.2014.99 |
0.684 |
|
| 2014 |
Hu QX, Dong JH, Du HB, Zhang DL, Ren HZ, Ma ML, Cai Y, Zhao TC, Yin XL, Yu X, Xue T, Xu ZG, Sun JP. Constitutive Gαi coupling activity of very large G protein-coupled receptor 1 (VLGR1) and its regulation by PDZD7 protein. The Journal of Biological Chemistry. 289: 24215-25. PMID 24962568 DOI: 10.1074/Jbc.M114.549816 |
0.733 |
|
| 2014 |
Wang HM, Dong JH, Li Q, Hu Q, Ning SL, Zheng W, Cui M, Chen TS, Xie X, Sun JP, Yu X. A stress response pathway in mice upregulates somatostatin level and transcription in pancreatic delta cells through Gs and β-arrestin 1. Diabetologia. 57: 1899-910. PMID 24947582 DOI: 10.1007/S00125-014-3290-0 |
0.336 |
|
| 2014 |
Kahsai AW, Rajagopal S, Sun J, Xiao K. Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry. Nature Protocols. 9: 1301-19. PMID 24810039 DOI: 10.1038/Nprot.2014.075 |
0.72 |
|
| 2014 |
Strachan RT, Sun JP, Rominger DH, Violin JD, Ahn S, Rojas Bie Thomsen A, Zhu X, Kleist A, Costa T, Lefkowitz RJ. Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR). The Journal of Biological Chemistry. 289: 14211-24. PMID 24668815 DOI: 10.1074/Jbc.M114.548131 |
0.796 |
|
| 2014 |
Li R, Xie DD, Dong JH, Li H, Li KS, Su J, Chen LZ, Xu YF, Wang HM, Gong Z, Cui GY, Yu X, Wang K, Yao W, Xin T, ... ... Sun JP, et al. Molecular mechanism of ERK dephosphorylation by striatal-enriched protein tyrosine phosphatase. Journal of Neurochemistry. 128: 315-29. PMID 24117863 DOI: 10.1111/Jnc.12463 |
0.641 |
|
| 2013 |
Jiang H, Sun J, Xu Q, Liu Y, Wei J, Young CY, Yuan H, Lou H. Marchantin M: a novel inhibitor of proteasome induces autophagic cell death in prostate cancer cells. Cell Death & Disease. 4: e761. PMID 23928700 DOI: 10.1038/Cddis.2013.285 |
0.362 |
|
| 2013 |
Pan C, Liu HD, Gong Z, Yu X, Hou XB, Xie DD, Zhu XB, Li HW, Tang JY, Xu YF, Yu JQ, Zhang LY, Fang H, Xiao KH, Chen YG, ... ... Sun JP, et al. Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site. Scientific Reports. 3: 2333. PMID 23903585 DOI: 10.1038/Srep02333 |
0.647 |
|
| 2013 |
Li R, Gong Z, Pan C, Xie DD, Tang JY, Cui M, Xu YF, Yao W, Pang Q, Xu ZG, Li MY, Yu X, Sun JP. Metal-dependent protein phosphatase 1A functions as an extracellular signal-regulated kinase phosphatase. The Febs Journal. 280: 2700-11. PMID 23560844 DOI: 10.1111/Febs.12275 |
0.676 |
|
| 2013 |
Li F, Shi P, Li J, Yang F, Wang T, Zhang W, Gao F, Ding W, Li D, Li J, Xiong Y, Sun J, Gong W, Tian C, Wang J. A genetically encoded 19F NMR probe for tyrosine phosphorylation. Angewandte Chemie (International Ed. in English). 52: 3958-62. PMID 23450644 DOI: 10.1002/Anie.201300463 |
0.414 |
|
| 2013 |
Sun J, Li R, Ren H, Xu A, Yu X, Xu Z. The very large G protein coupled receptor (Vlgr1) in hair cells. Journal of Molecular Neuroscience. 50: 204-214. PMID 23180093 DOI: 10.1007/S12031-012-9911-5 |
0.423 |
|
| 2012 |
Liu J, Chen M, Li R, Yang F, Shi X, Zhu L, Wang HM, Yao W, Liu Q, Meng FG, Sun JP, Pang Q, Yu X. Biochemical and functional studies of Lymphoid-specific tyrosine phosphatase (Lyp) variants S201F and R266W Plos One. 7. PMID 22952725 DOI: 10.1371/Journal.Pone.0043631 |
0.369 |
|
| 2012 |
Dong JH, Chen X, Cui M, Yu X, Pang Q, Sun JP. β2-adrenergic receptor and astrocyte glucose metabolism. Journal of Molecular Neuroscience : Mn. 48: 456-63. PMID 22399228 DOI: 10.1007/S12031-012-9742-4 |
0.345 |
|
| 2012 |
Dou HQ, Xu YF, Sun JP, Shang S, Guo S, Zheng LH, Chen CC, Bruce IC, Yu X, Zhou Z. Thiopental-induced insulin secretion via activation of IP3-sensitive calcium stores in rat pancreatic β-cells. American Journal of Physiology. Cell Physiology. 302: C796-803. PMID 22135216 DOI: 10.1152/Ajpcell.00081.2011 |
0.61 |
|
| 2012 |
Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of β-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 34 (15299-15304) doi:10.1073/pnas.1008461107) Proceedings of the National Academy of Sciences of the United States of America. 109: 13464. DOI: 10.1073/Pnas.1211889109 |
0.778 |
|
| 2011 |
Kahsai AW, Xiao K, Rajagopal S, Ahn S, Shukla AK, Sun J, Oas TG, Lefkowitz RJ. Multiple ligand-specific conformations of the β2-adrenergic receptor. Nature Chemical Biology. 7: 692-700. PMID 21857662 DOI: 10.1038/Nchembio.634 |
0.83 |
|
| 2011 |
Yu X, Chen M, Zhang S, Yu ZH, Sun JP, Wang L, Liu S, Imasaki T, Takagi Y, Zhang ZY. Substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrate. The Journal of Biological Chemistry. 286: 30526-34. PMID 21719704 DOI: 10.1074/jbc.M111.254722 |
0.489 |
|
| 2008 |
Lefkowitz RJ, Sun JP, Shukla AK. A crystal clear view of the beta2-adrenergic receptor. Nature Biotechnology. 26: 189-91. PMID 18259173 DOI: 10.1038/Nbt0208-189 |
0.606 |
|
| 2008 |
Shukla AK, Sun JP, Lefkowitz RJ. Crystallizing thinking about the beta2-adrenergic receptor. Molecular Pharmacology. 73: 1333-8. PMID 18239031 DOI: 10.1124/Mol.108.045849 |
0.587 |
|
| 2007 |
Yu X, Sun JP, He Y, Guo X, Liu S, Zhou B, Hudmon A, Zhang ZY. Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases. Proceedings of the National Academy of Sciences of the United States of America. 104: 19767-72. PMID 18056643 DOI: 10.1073/Pnas.0706233104 |
0.5 |
|
| 2007 |
Sun JP, Luo Y, Yu X, Wang WQ, Zhou B, Liang F, Zhang ZY. Phosphatase activity, trimerization, and the C-terminal polybasic region are all required for PRL1-mediated cell growth and migration. The Journal of Biological Chemistry. 282: 29043-51. PMID 17656357 DOI: 10.1074/jbc.M703537200 |
0.469 |
|
| 2007 |
Liang F, Liang J, Wang WQ, Sun JP, Udho E, Zhang ZY. PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activation. The Journal of Biological Chemistry. 282: 5413-9. PMID 17192274 DOI: 10.1074/jbc.M608940200 |
0.454 |
|
| 2006 |
Liu S, Sun JP, Zhou B, Zhang ZY. Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3. Proceedings of the National Academy of Sciences of the United States of America. 103: 5326-31. PMID 16567630 DOI: 10.1073/pnas.0510506103 |
0.474 |
|
| 2005 |
Sun JP, Wang WQ, Yang H, Liu S, Liang F, Fedorov AA, Almo SC, Zhang ZY. Structure and biochemical properties of PRL-1, a phosphatase implicated in cell growth, differentiation, and tumor invasion. Biochemistry. 44: 12009-21. PMID 16142898 DOI: 10.1021/Bi0509191 |
0.459 |
|
| 2003 |
Sun JP, Wu L, Fedorov AA, Almo SC, Zhang ZY. Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor Journal of Biological Chemistry. 278: 33392-33399. PMID 12810712 DOI: 10.1074/Jbc.M304693200 |
0.47 |
|
| 2003 |
Wang WQ, Sun JP, Zhang ZY. An overview of the protein tyrosine phosphatase superfamily. Current Topics in Medicinal Chemistry. 3: 739-48. PMID 12678841 DOI: 10.2174/1568026033452302 |
0.494 |
|
| 2003 |
Sun JP, Fedorov AA, Lee SY, Guo XL, Shen K, Lawrence DS, Almo SC, Zhang ZY. Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor. The Journal of Biological Chemistry. 278: 12406-14. PMID 12547827 DOI: 10.1074/Jbc.M212491200 |
0.482 |
|
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