YoungSoo Kim, Ph.D. - Publications

Affiliations: 
2006-2017 Brain Science Institute Korea Institute of Science and Technology (KIST) 
 2017- Department of Pharmacy Yonsei University, Seoul, South Korea 
Area:
Chemical Biology, Bioorganic Chemistry, Peptide Chemistry, Alzheimer's disease
Website:
http://chembio.yonsei.ac.kr/

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 An J, Kim K, Lim HJ, Kim HY, Shin J, Park I, Cho I, Kim HY, Kim S, McLean C, Choi KY, Kim Y, Lee KH, Kim JS. Early onset diagnosis in Alzheimer's disease patients via amyloid-β oligomers-sensing probe in cerebrospinal fluid. Nature Communications. 15: 1004. PMID 38307843 DOI: 10.1038/s41467-024-44818-x  0.528
2023 Cha M, Dagar A, Lee S, Cho I, Lee D, Kim K, Park I, Yoon S, Kim HY, Kim I, Kim Y. Benzo[]imidazole-pyrrolo[1,2-]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice. Acs Chemical Neuroscience. PMID 37552840 DOI: 10.1021/acschemneuro.2c00547  0.701
2023 Kim J, Jeon H, Kim HY, Kim Y. Failure, Success, and Future Direction of Alzheimer Drugs Targeting Amyloid-β Cascade: Pros and Cons of Chemical and Biological Modalities. Chembiochem : a European Journal of Chemical Biology. e202300328. PMID 37497809 DOI: 10.1002/cbic.202300328  0.854
2023 Lee D, Ryoo JE, Hong S, Kim HY, Kim Y. Carprofen alleviates Alzheimer-like phenotypes of 5XFAD transgenic mice by targeting the pathological hallmarks induced by amyloid-β aggregation. Scientific Reports. 13: 10889. PMID 37407605 DOI: 10.1038/s41598-023-36167-4  0.801
2023 Yoon M, Kim H, Shin H, Lee H, Kang MJ, Park SH, Han G, Kim Y, Choi KY. Inhibition of CXXC5 function rescues Alzheimer's disease phenotypes by restoring Wnt/β-catenin signaling pathway. Pharmacological Research. 194: 106836. PMID 37355147 DOI: 10.1016/j.phrs.2023.106836  0.862
2023 Lee S, Dagar A, Cho I, Kim K, Park IW, Yoon S, Cha M, Shin J, Kim HY, Kim I, Kim Y. 4-Acyl-3,4-dihydropyrrolo[1,2-]pyrazine Derivative Rescued the Hippocampal-Dependent Cognitive Decline of 5XFAD Transgenic Mice by Dissociating Soluble and Insoluble Aβ Aggregates. Acs Chemical Neuroscience. PMID 37171100 DOI: 10.1021/acschemneuro.2c00788  0.699
2023 Cui J, Ye S, Shin D, Cho I, Kim HY, Kwon Y, Park K, Nam SJ, Kim Y, Oh DC. Glycosylated and Succinylated Macrocyclic Lactones with Amyloid-β-Aggregation-Regulating Activity from a Marine sp. Marine Drugs. 21. PMID 36827108 DOI: 10.3390/md21020067  0.565
2023 Poellmann MJ, Bu J, Liu S, Wang AZ, Seyedin SN, Chandrasekharan C, Hong H, Kim Y, Caster JM, Hong S. Nanotechnology and machine learning enable circulating tumor cells as a reliable biomarker for radiotherapy responses of gastrointestinal cancer patients. Biosensors & Bioelectronics. 226: 115117. PMID 36753988 DOI: 10.1016/j.bios.2023.115117  0.461
2023 Cho I, Lee H, Lee D, Park IW, Yoon S, Kim HY, Kim Y. Solid-phase synthesis and pathological evaluation of pyroglutamate amyloid-β peptide. Scientific Reports. 13: 505. PMID 36627316 DOI: 10.1038/s41598-022-26616-x  0.851
2022 Cho I, Yoon S, Park S, Hong SW, Cho E, Kim E, Kim HY, Kim Y. Immobilized Amyloid Hexamer Fragments to Map Active Sites of Amyloid-Targeting Chemicals. Acs Chemical Neuroscience. PMID 36445044 DOI: 10.1021/acschemneuro.2c00449  0.619
2022 Jung M, Lee S, Park S, Hong J, Kim C, Cho I, Sohn HS, Kim K, Park IW, Yoon S, Kwon S, Shin J, Lee D, Kang M, Go S, ... ... Kim Y, et al. A Therapeutic Nanovaccine that Generates Anti-amyloid Antibodies and Amyloid-specific Regulatory T cells for Alzheimer's Disease. Advanced Materials (Deerfield Beach, Fla.). e2207719. PMID 36329674 DOI: 10.1002/adma.202207719  0.854
2022 Lee H, Baek S, Cha M, Yang SH, Cho I, Shin H, Lee S, Kim HY, Lee S, Shin J, Lee D, Kim K, Park I, Yoon S, Kim J, ... ... Kim Y, et al. Amyloid Against Amyloid: Dimeric Amyloid Fragment Ameliorates Cognitive Impairments by Direct Clearance of Oligomers and Plaques. Angewandte Chemie (International Ed. in English). PMID 36316282 DOI: 10.1002/anie.202210209  0.862
2022 Jeong H, Shin H, Hong S, Kim Y. Physiological Roles of Monomeric Amyloid-β and Implications for Alzheimer's Disease Therapeutics. Experimental Neurobiology. 31: 65-88. PMID 35673997 DOI: 10.5607/en22004  0.768
2022 Lee D, Kim HV, Kim HY, Kim Y. Chemical-Driven Outflow of Dissociated Amyloid Burden from Brain to Blood. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2104542. PMID 35106958 DOI: 10.1002/advs.202104542  0.828
2021 Kim K, Lee JH, Kim S, Lee S, Lee D, Kim HY, Kim I, Kim Y. Anti-amyloidogenic indolizino[3,2-]quinolines as imaging probes differentiating dense-core, diffuse, and coronal plaques of amyloid-β. Rsc Medicinal Chemistry. 12: 1926-1934. PMID 34825188 DOI: 10.1039/d1md00030f  0.695
2021 Park S, Kim Y. Bias-generating factors in biofluid amyloid-β measurements for Alzheimer's disease diagnosis. Biomedical Engineering Letters. 11: 287-295. PMID 34616582 DOI: 10.1007/s13534-021-00201-z  0.869
2021 Rawding PA, Bu J, Wang J, Kim DW, Drelich AJ, Kim Y, Hong S. Dendrimers for cancer immunotherapy: Avidity-based drug delivery vehicles for effective anti-tumor immune response. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. e1752. PMID 34414690 DOI: 10.1002/wnan.1752  0.515
2021 Park S, Kim HY, Oh HA, Shin J, Park IW, Yoon S, Woo DH, Kim Y. Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer's disease. Scientific Reports. 11: 12043. PMID 34103615 DOI: 10.1038/s41598-021-91563-y  0.87
2021 Zheng M, Choi N, Jang Y, Kwak DE, Kim Y, Kim WS, Oh SH, Sung JH. Author Correction: Hair growth promotion by Necrostatin-1s. Scientific Reports. 11: 9082. PMID 33883684 DOI: 10.1038/s41598-021-88759-7  0.742
2021 Kim D, Lee JH, Kim HY, Shin J, Kim K, Lee S, Park J, Kim I, Kim Y. Correction: Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model. Plos One. 16: e0250194. PMID 33831134 DOI: 10.1371/journal.pone.0250194  0.835
2021 Shin J, Yang SH, Du YE, Park K, Kim D, Shin D, Kim J, Kim SH, Kim YK, Shin J, Oh DC, Kim Y. Borrelidin from Saltern-Derived Halophilic sp. Dissociates Amyloid- and Tau Fibrils. Journal of Alzheimer's Disease Reports. 5: 7-13. PMID 33681712 DOI: 10.3233/ADR-200247  0.878
2021 Shin J, Park S, Lee H, Kim Y. Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model. Scientific Reports. 11: 1617. PMID 33452414 DOI: 10.1038/s41598-021-81304-6  0.851
2020 Kim D, Lee JH, Kim HY, Shin J, Kim K, Lee S, Park J, Kim J, Kim Y. Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model. Plos One. 15: e0243041. PMID 33362250 DOI: 10.1371/journal.pone.0243041  0.875
2020 Kim D, Bae GH, Kim HY, Jeon H, Kim K, Shin J, Lee S, Hong S, Kim I, Kim Y. Orally Administered Benzofuran Derivative Disaggregated Aβ Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse. Acs Chemical Neuroscience. PMID 33332107 DOI: 10.1021/acschemneuro.0c00606  0.87
2020 Zheng M, Choi N, Jang Y, Kwak DE, Kim Y, Kim WS, Oh SH, Sung JH. Hair growth promotion by necrostatin-1s. Scientific Reports. 10: 17622. PMID 33077863 DOI: 10.1038/s41598-020-74796-1  0.767
2020 Kim HY, Lee H, Lee JK, Kim HV, Kim KS, Kim Y. Bicine promotes rapid formation of β-sheet-rich amyloid-β fibrils. Plos One. 15: e0240608. PMID 33048999 DOI: 10.1371/journal.pone.0240608  0.853
2020 Kwon Y, Shin J, Nam K, An JS, Yang SH, Hong SH, Bae M, Moon K, Cho Y, Woo J, Park K, Kim K, Shin J, Kim BY, Kim Y, et al. Rhizolutin, a novel 7/10/6-tricyclic dilactone, dissociates misfolded protein aggregates and reduces apoptosis/inflammation associated with Alzheimer's disease. Angewandte Chemie (International Ed. in English). PMID 32844539 DOI: 10.1002/Anie.202009294  0.817
2020 Yoo SJ, Son G, Bae J, Kim SY, Yoo YK, Park D, Baek SY, Chang KA, Suh YH, Lee YB, Hwang KS, Kim Y, Moon C. Longitudinal profiling of oligomeric Aβ in human nasal discharge reflecting cognitive decline in probable Alzheimer's disease. Scientific Reports. 10: 11234. PMID 32641719 DOI: 10.1038/S41598-020-68148-2  0.805
2020 Choi JW, Ju YH, Choi Y, Hyeon SJ, Gadhe CG, Park JH, Kim MS, Baek S, Kim Y, Park KD, Pae AN, Ryu H, Lee CJ, Cho BR. PyrPeg, a Blood-Brain Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, not Tau Aggregates. Acs Chemical Neuroscience. PMID 32421307 DOI: 10.1021/Acschemneuro.0C00211  0.688
2020 Lee JC, Kim HY, Lee S, Shin J, Kim HV, Kim K, Baek S, Lee D, Jeon H, Kim D, Yang SH, Han G, Park K, Choi J, Park J, ... ... Kim Y, et al. Discovery of chemicals to clear or indicate amyloid aggregates by targeting memory-impairing anti-parallel Aβ dimers. Angewandte Chemie (International Ed. in English). PMID 32233096 DOI: 10.1002/Anie.202002574  0.825
2020 Lee H, Ugay D, Hong S, Kim Y. Alzheimer's Disease Diagnosis Using Misfolding Proteins in Blood. Dementia and Neurocognitive Disorders. PMID 32174051 DOI: 10.12779/Dnd.2020.19.1.1  0.856
2020 Kim B, Shin J, Kim Y, Choi JH. Destruction of ERP responses to deviance in an auditory oddball paradigm in amyloid infusion mice with memory deficits. Plos One. 15: e0230277. PMID 32160242 DOI: 10.1371/Journal.Pone.0230277  0.565
2020 Heo JY, Nam MH, Yoon HH, Kim J, Hwang YJ, Won W, Woo DH, Lee JA, Park HJ, Jo S, Lee MJ, Kim S, Shim JE, Jang DP, Kim KI, ... ... Kim Y, et al. Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's Disease. Current Biology : Cb. PMID 31928877 DOI: 10.1016/J.Cub.2019.11.079  0.608
2020 Kwak DE, Ko T, Koh HS, Ji YW, Shin J, Kim K, Kim HY, Lee HK, Kim Y. Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease. Plos One. 15: e0227618. PMID 31923257 DOI: 10.1371/Journal.Pone.0227618  0.827
2020 Baek S, Park S, Shin J, Lee JS, Kim HY, Han G, Kim YS. Investigation of memory-enhancing botanical mixture and their isolated compounds for inhibition of amyloid-β and tau aggregation Applied Biological Chemistry. 63: 1-7. DOI: 10.1186/S13765-020-00507-Z  0.476
2020 Yoo YK, Kim G, Park D, Kim J, Kim Y, Yun Kim H, Yang SH, Lee JH, Hwang KS. Gold nanoparticles assisted sensitivity improvement of interdigitated microelectrodes biosensor for amyloid-β detection in plasma sample Sensors and Actuators B: Chemical. 308: 127710. DOI: 10.1016/J.Snb.2020.127710  0.548
2019 Yang TW, Kim DH, Kim YS, Kim J, Kwon OY. Anxiety disorders in outpatient clinics of epilepsy in tertiary care hospitals: A meta-analysis. Seizure. 75: 34-42. PMID 31874357 DOI: 10.1016/j.seizure.2019.12.011  0.303
2019 Kim DK, Han D, Park J, Choi H, Park JC, Cha MY, Woo J, Byun MS, Lee DY, Kim Y, Mook-Jung I. Deep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer's disease. Experimental & Molecular Medicine. 51: 136. PMID 31727875 DOI: 10.1038/s12276-019-0326-z  0.489
2019 Lee H, Kim D, Lee W, Kim HY, Kim Y. Preventive approach for overcoming dementia. Archives of Pharmacal Research. PMID 31187441 DOI: 10.1007/S12272-019-01168-3  0.785
2019 Lee JC, Kim SJ, Hong S, Kim Y. Diagnosis of Alzheimer's disease utilizing amyloid and tau as fluid biomarkers. Experimental & Molecular Medicine. 51: 53. PMID 31073121 DOI: 10.1038/S12276-019-0250-2  0.841
2019 Neo Shin N, Jeon H, Jung Y, Baek S, Lee S, Yoo HC, Bae GH, Park K, Yang SH, Han JM, Kim I, Kim Y. Fluorescent 1,4-Naphthoquinones To Visualize Diffuse and Dense-Core Amyloid Plaques in APP/PS1 Transgenic Mouse Brains. Acs Chemical Neuroscience. PMID 31016960 DOI: 10.1021/Acschemneuro.9B00093  0.844
2019 Lee D, Kim SM, Kim HY, Kim Y. Fluorescence chemicals to detect insoluble and soluble amyloid-β aggregates. Acs Chemical Neuroscience. PMID 31009195 DOI: 10.1021/Acschemneuro.9B00199  0.706
2019 Kim Y, Yoo YK, Kim HY, Roh JH, Kim J, Baek S, Lee JC, Kim HJ, Chae MS, Jeong D, Park D, Lee S, Jang H, Kim K, Lee JH, et al. Comparative analyses of plasma amyloid-β levels in heterogeneous and monomerized states by interdigitated microelectrode sensor system. Science Advances. 5: eaav1388. PMID 31001580 DOI: 10.1126/Sciadv.Aav1388  0.849
2019 Yang SH, Shin J, Shin NN, Hwang JH, Hong SC, Park K, Lee JW, Lee S, Baek S, Kim K, Cho I, Kim Y. A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice. Scientific Reports. 9: 4183. PMID 30862818 DOI: 10.1038/S41598-019-40205-5  0.868
2019 Jun YW, Cho SW, Jung J, Huh Y, Kim Y, Kim D, Ahn KH. Frontiers in Probing Alzheimer's Disease Biomarkers with Fluorescent Small Molecules. Acs Central Science. 5: 209-217. PMID 30834309 DOI: 10.1021/Acscentsci.8B00951  0.531
2019 Kim HJ, Park D, Baek SY, Yang SH, Kim Y, Lim SM, Kim J, Hwang KS. Dielectrophoresis-based filtration effect and detection of amyloid beta in plasma for Alzheimer's disease diagnosis. Biosensors & Bioelectronics. 128: 166-175. PMID 30660932 DOI: 10.1016/j.bios.2018.12.046  0.819
2018 Jeong WJ, Bu J, Kubiatowicz LJ, Chen SS, Kim Y, Hong S. Peptide-nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms? Nano Convergence. 5: 38. PMID 30539365 DOI: 10.1186/S40580-018-0170-1  0.473
2018 Choi H, Jeong JH, Kim YB, Jo KD, Choi JY, Kang KH, Kang H, Kwon DY, Yoo BG, Lee HJ, Shin BS, Jeon SM, Kwon OD, Kim JS, Lee SJ, ... ... Kim Y, ... ... Kim YJ, et al. Observational Study of Clinical and Functional Progression Based on Initial Brain MRI Characteristics in Patients with Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30452413 DOI: 10.3233/JAD-180565  0.367
2018 Shim HG, Jang SS, Kim SH, Hwang EM, Min JO, Kim HY, Kim YS, Ryu C, Chung G, Kim Y, Yoon BE, Kim SJ. TNF-α increases the intrinsic excitability of cerebellar Purkinje cells through elevating glutamate release in Bergmann Glia. Scientific Reports. 8: 11589. PMID 30072733 DOI: 10.1038/S41598-018-29786-9  0.332
2018 Jeong D, Kim J, Chae MS, Lee W, Yang SH, Kim Y, Kim SM, Lee JS, Lee JH, Choi J, Yoon DS, Hwang KS. Multifunctionalized Reduced Graphene Oxide Biosensors for Simultaneous Monitoring of Structural Changes in Amyloid-β 40. Sensors (Basel, Switzerland). 18. PMID 29843431 DOI: 10.3390/S18061738  0.8
2018 Kim DK, Park J, Han D, Yang J, Kim A, Woo J, Kim Y, Mook-Jung I. Molecular and functional signatures in a novel Alzheimer's disease mouse model assessed by quantitative proteomics. Molecular Neurodegeneration. 13: 2. PMID 29338754 DOI: 10.1186/s13024-017-0234-4  0.524
2017 Jang H, Lee S, Choi SL, Kim HY, Baek S, Kim Y. Taurine Directly Binds to Oligomeric Amyloid-β and Recovers Cognitive Deficits in Alzheimer Model Mice. Advances in Experimental Medicine and Biology. 975: 233-241. PMID 28849459 DOI: 10.1007/978-94-024-1079-2_21  0.856
2017 Kim HY, Yang SH, Yoon J, Jang H, Baek S, Shin J, Kim SH, Kim Y. Taurine-Carbohydrate Derivative Stimulates Fibrillogenesis of Amyloid-β and Reduce Alzheimer-Like Behaviors. Advances in Experimental Medicine and Biology. 975: 225-232. PMID 28849458 DOI: 10.1007/978-94-024-1079-2_20  0.882
2017 Oh SJ, Kim MH, Han SJ, Kang KJ, Ko IO, Kim Y, Park JA, Choi JY, Lee KC, Chi DY, Lee YJ, Kim KM. Preliminary PET study of (18)F-FC119S in normal and Alzheimer's disease models. Molecular Pharmaceutics. PMID 28737945 DOI: 10.1021/Acs.Molpharmaceut.7B00351  0.433
2017 Yang S, Lee D, Shin J, Lee S, Baek S, Kim Y. NEC-1 ALLEVIATES COGNITIVE IMPAIRMENT WITH REDUCTION OF Aβ AND TAU ABNORMALITIES IN APP/PS1 MICE Alzheimers & Dementia. 13: 987. DOI: 10.1016/J.Jalz.2017.06.1347  0.483
2016 Singh A, Kim W, Kim Y, Jeong K, Kang CS, Kim Y, Koh J, Mahajan SD, Prasad PN, Kim S. Multifunctional Photonics Nanoparticles for Crossing the Blood-Brain Barrier and Effecting Optically Trackable Brain Theranostics. Advanced Functional Materials. 26: 7057-7066. PMID 29081729 DOI: 10.1002/Adfm.201602808  0.522
2016 Yang SH, Lee DK, Shin J, Lee S, Baek S, Kim J, Jung H, Hah JM, Kim Y. Nec-1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice. Embo Molecular Medicine. PMID 27861127 DOI: 10.15252/emmm.201606566  0.85
2016 Kim HY, Kim HV, Lee DK, Yang SH, Kim Y. Rapid and sustained cognitive recovery in APP/PS1 transgenic mice by co-administration of EPPS and donepezil. Scientific Reports. 6: 34165. PMID 27796293 DOI: 10.1038/Srep34165  0.855
2016 Kang BR, Yang SH, Chung BR, Kim W, Kim Y. Cell surface GRP78 as a biomarker and target for suppressing glioma cells. Scientific Reports. 6: 34922. PMID 27713511 DOI: 10.1038/srep34922  0.688
2016 Kim J, Chae MS, Lee SM, Jeong D, Lee BC, Lee JH, Kim Y, Chang ST, Hwang KS. Wafer-scale high-resolution patterning of reduced graphene oxide films for detection of low concentration biomarkers in plasma. Scientific Reports. 6: 31276. PMID 27506288 DOI: 10.1038/Srep31276  0.371
2016 Kim HY, Lee DK, Chung BR, Kim HV, Kim Y. Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits. Journal of Visualized Experiments : Jove. PMID 27023127 DOI: 10.3791/53308  0.823
2016 Kim HY, Kim HV, Jo S, Lee CJ, Choi SY, Kim DJ, Kim Y. Corrigendum: EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nature Communications. 7: 10755. PMID 26877163 DOI: 10.1038/Ncomms10755  0.725
2016 Cho SM, Lee S, Yang SH, Kim HY, Lee MJ, Kim HV, Kim J, Baek S, Yun J, Kim D, Kim YK, Cho Y, Woo J, Kim TS, Kim Y. Age-dependent inverse correlations in CSF and plasma amyloid-β(1-42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice. Scientific Reports. 6: 20185. PMID 26830653 DOI: 10.1038/Srep20185  0.867
2016 Kim Y, Kim HY, Kim HV, Jo S, Lee CJ, Choi SY. O5-03-03: Epps Reverses Amyloid-B Aggregation and Ameliorates Hippocampus-Dependent Cognitive Deficits in APP/PS1 Mice Alzheimer's & Dementia. 12: P383-P383. DOI: 10.1016/J.Jalz.2016.06.718  0.434
2016 Lee S, Cho SM, Yang S, Kim HY, Kim J, Baek S, Kim Y. Age-Dependent Inverse Corrleations In Csf And Plasma Amyloid-B(1-42) Concentrations Prior To Amyloid Plaque Deposition In The Brain Of 3Xtg-Ad Mice Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.1828  0.565
2015 Kim HY, Kim HV, Jo S, Lee CJ, Choi SY, Kim DJ, Kim Y. EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nature Communications. 6: 8997. PMID 26646366 DOI: 10.1038/Ncomms9997  0.845
2015 Yang SH, Kim J, Lee MJ, Kim Y. Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model. Scientific Reports. 5: 15703. PMID 26503550 DOI: 10.1038/Srep15703  0.775
2015 Yang Y, Kim J, Kim HY, Ryoo N, Lee S, Kim Y, Rhim H, Shin YK. Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a. Cell Reports. PMID 26279571 DOI: 10.1016/J.Celrep.2015.07.044  0.753
2014 Kim HY, Kim HV, Yoon JH, Kang BR, Cho SM, Lee S, Kim JY, Kim JW, Cho Y, Woo J, Kim Y. Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease. Scientific Reports. 4: 7467. PMID 25502280 DOI: 10.1038/srep07467  0.839
2014 Cho SM, Kim HV, Lee S, Kim HY, Kim W, Kim TS, Kim DJ, Kim Y. Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model. Scientific Reports. 4: 6777. PMID 25345439 DOI: 10.1038/srep06777  0.871
2014 Kim JS, Ahn HS, Cho SM, Lee JE, Kim Y, Lee C. Detection and quantification of plasma amyloid-β by selected reaction monitoring mass spectrometry. Analytica Chimica Acta. 840: 1-9. PMID 25086887 DOI: 10.1016/j.aca.2014.06.024  0.801
2014 Jo S, Yarishkin O, Hwang YJ, Chun YE, Park M, Woo DH, Bae JY, Kim T, Lee J, Chun H, Park HJ, Lee da Y, Hong J, Kim HY, Oh SJ, ... ... Kim Y, et al. GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease. Nature Medicine. 20: 886-96. PMID 24973918 DOI: 10.1038/Nm.3639  0.618
2014 Lee SH, Kim Y, Kim HY, Kim YH, Kim MS, Kong JY, Lee MH, Kim DJ, Ahn YG. Aminostyrylbenzofuran directly reduces oligomeric amyloid-β and reverses cognitive deficits in Alzheimer transgenic mice. Plos One. 9: e95733. PMID 24760018 DOI: 10.1371/Journal.Pone.0095733  0.603
2014 Hyunjin KV, Kim HY, Kim DJ, Kim Y. P1-423: SYNERGISTIC NEUROPROTECTIVE EFFECT OF KMSB600 AND DONEPEZIL IN THE ALZHEIMER'S DISEASE ANIMAL MODEL Alzheimer's & Dementia. 10: P468-P469. DOI: 10.1016/J.Jalz.2014.05.666  0.39
2014 Lee S, Kim HY, Kim Y. P1-118: SYNTHESES OF BIOLOGICALLY ACTIVE AND COVALENTLY BONDED AMYLOID-B DIMERS Alzheimer's & Dementia. 10: P344-P344. DOI: 10.1016/J.Jalz.2014.05.355  0.319
2013 Tak H, Haque MM, Kim MJ, Lee JH, Baik JH, Kim Y, Kim DJ, Grailhe R, Kim YK. Bimolecular fluorescence complementation; lighting-up tau-tau interaction in living cells. Plos One. 8: e81682. PMID 24312574 DOI: 10.1371/Journal.Pone.0081682  0.432
2013 Lee YS, Kim HY, Youn HM, Seo JH, Kim Y, Shin KJ. 2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of β-amyloid aggregation. Bioorganic & Medicinal Chemistry Letters. 23: 5882-6. PMID 24076170 DOI: 10.1016/J.Bmcl.2013.08.087  0.58
2013 Kim HV, Kim HY, Ehrlich HY, Choi SY, Kim DJ, Kim Y. Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 20: 7-12. PMID 23253046 DOI: 10.3109/13506129.2012.751367  0.784
2013 Kim HY, Kim HV, Ehrlich H, Choi SY, Kim DJ, Kim Y. P1-030: Amelioration of Alzheimer's disease by the neuroprotective effect of sulforaphane in an animal model Alzheimer's & Dementia. 9: P162-P163. DOI: 10.1016/J.Jalz.2013.05.250  0.388
2012 Lee YS, Kim HY, Kim Y, Seo JH, Roh EJ, Han H, Shin KJ. Small molecules that protect against β-amyloid-induced cytotoxicity by inhibiting aggregation of β-amyloid. Bioorganic & Medicinal Chemistry. 20: 4921-35. PMID 22831802 DOI: 10.1016/J.Bmc.2012.06.045  0.698
2012 Choi JW, Kim HY, Jeon M, Kim DJ, Kim Y. Efficient access to highly pure β-amyloid peptide by optimized solid-phase synthesis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 19: 133-7. PMID 22799493 DOI: 10.3109/13506129.2012.700287  0.806
2011 Lee JS, Kim HY, Kim DJ, Kim Y. P4-319: Facile synthesis of beta-amyloid by solid-phase peptide synthesis Alzheimer's & Dementia. 7: e22-e22. DOI: 10.1016/J.Jalz.2011.09.064  0.301
2010 Kim HY, Kim Y, Han G, Kim DJ. Regulation of in vitro Aβ1-40 aggregation mediated by small molecules. Journal of Alzheimer's Disease : Jad. 22: 73-85. PMID 20847447 DOI: 10.3233/Jad-2010-100183  0.714
2010 Hong MC, Kim YK, Choi JY, Yang SQ, Rhee H, Ryu YH, Choi TH, Cheon GJ, An GI, Kim HY, Kim Y, Kim DJ, Lee JS, Chang YT, Lee KC. Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques. Bioorganic & Medicinal Chemistry. 18: 7724-30. PMID 20621493 DOI: 10.1016/J.Bmc.2010.06.044  0.702
2010 Choi J, Kim Y, Lee JH, Lim SJ, Oh SJ, Moon DH, Kim DJ. IC-P-088: Fluoroisoindolone Derivatives as Potential PET Imaging Agents for Detection of Beta-Amyloid Fibrils Alzheimer's & Dementia. 6: S36-S36. DOI: 10.1016/J.Jalz.2010.05.102  0.317
2009 Kim Y, Lee JH, Ryu J, Kim DJ. Multivalent & multifunctional ligands to beta-amyloid. Current Pharmaceutical Design. 15: 637-58. PMID 19199987 DOI: 10.2174/138161209787315648  0.341
2009 Kim H, Kim Y, Han G, Kim DJ. Disaggregation of β-amyloid plaques by KMSB600 Alzheimers & Dementia. 5: 421. DOI: 10.1016/J.Jalz.2009.04.937  0.499
2009 Kim Y, Byun JH, Ryu J, Hwang H, Lee JH, Cho J, Kim H, Ahn Y, Kim YH, Kim MS, Lee GS, Mook-Jung I, Yoo KH, Kim DJ. KMS88009 and KMS88016 as small molecule inhibitors for in vivo Aβ fibril formation Alzheimers & Dementia. 5: 421. DOI: 10.1016/J.Jalz.2009.04.936  0.437
2008 Lee JH, Lim SJ, Lee SJ, Kim Y, Oh SJ, Moon DH, Yoo KH, Kim DJ. P2-035: Dihydroisoindolone derivatives as potential PET imaging agents for detection of beta-amyloid fibrils Alzheimer's & Dementia. 4: T378-T378. DOI: 10.1016/J.Jalz.2008.05.1116  0.427
2008 Kim H, Kim Y, Kim DJ. P1-440: Biological tactics to control in vitro beta-amyloid aggregation Alzheimer's & Dementia. 4: T348-T349. DOI: 10.1016/J.Jalz.2008.05.1022  0.461
2007 Liu Y, Steiniger SC, Kim Y, Kaufmann GF, Felding-Habermann B, Janda KD. Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery. Molecular Pharmaceutics. 4: 435-47. PMID 17373820 DOI: 10.1021/Mp060122J  0.449
2006 Kim Y, Lillo AM, Steiniger SC, Liu Y, Ballatore C, Anichini A, Mortarini R, Kaufmann GF, Zhou B, Felding-Habermann B, Janda KD. Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand. Biochemistry. 45: 9434-44. PMID 16878978 DOI: 10.1021/Bi060264J  0.502
2006 Ma H, Zhou B, Kim Y, Janda KD. A cyclic peptide-polymer probe for the detection of Clostridium botulinum neurotoxin serotype A. Toxicon : Official Journal of the International Society On Toxinology. 47: 901-8. PMID 16730044 DOI: 10.1016/J.Toxicon.2006.03.003  0.445
2006 Kim HJ, Kim J, Kim Y, Park JH, Hwang KS. P2-096: PLASMA-BASED AMYLOID BETA ANALYZING PLATFORM FOR DIAGNOSIS OF ALZHEIMER'S DISEASE (AD) Alzheimer's & Dementia. 14: P704-P704. DOI: 10.1016/J.Jalz.2018.06.781  0.586
2005 Kim Y, Lillo A, Moss JA, Janda KD. A contiguous stretch of methionine residues mediates the energy-dependent internalization mechanism of a cell-penetrating peptide. Molecular Pharmaceutics. 2: 528-35. PMID 16323960 DOI: 10.1021/Mp050035B  0.661
2005 Lee Y, Kim Y. Water - solubility of β - Glucans in Various Edible Mushrooms Journal of Food Science and Nutrition. 10: 294-297. DOI: 10.3746/Jfn.2005.10.3.294  0.309
2004 Kim D, Chae JC, Zylstra GJ, Kim YS, Kim SK, Nam MH, Kim YM, Kim E. Identification of a novel dioxygenase involved in metabolism of o-xylene, toluene, and ethylbenzene by Rhodococcus sp. strain DK17. Applied and Environmental Microbiology. 70: 7086-92. PMID 15574904 DOI: 10.1128/Aem.70.12.7086-7092.2004  0.412
2002 Walsh DP, Pang C, Parikh PB, Kim YS, Chang YT. Comparative resin kinetics using in situ fluorescence measurements. Journal of Combinatorial Chemistry. 4: 204-8. PMID 12005479 DOI: 10.1021/Cc010063T  0.49
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