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Nazish Sayed - Publications

Affiliations: 
Stanford University Medical School 
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tripathi D, Manhas A, Noishiki C, Wu D, Adkar S, Sallam K, Fukaya E, Leeper NJ, Sayed N. Generation of induced pluripotent stem cell line from a patient suffering from arterial calcification due to deficiency of CD73 (ACDC). Stem Cell Research. 75: 103285. PMID 38199067 DOI: 10.1016/j.scr.2023.103285  0.649
2023 Liu C, Shen M, Tan WLW, Chen IY, Liu Y, Yu X, Yang H, Zhang A, Liu Y, Zhao MT, Ameen M, Zhang M, Gross ER, Qi LS, Sayed N, et al. Statins improve endothelial function via suppression of epigenetic-driven EndMT. Nature Cardiovascular Research. 2: 467-485. PMID 37693816 DOI: 10.1038/s44161-023-00267-1  0.742
2022 Ramachandra AB, Wang H, Wnorowski A, Schwarz EL, Pickering J, Heiler JC, Lucian HJ, Hironaka CE, Tran NA, Liu Y, Khan MO, Obafemi O, Tada Y, Kahn AM, Sayed N, et al. Biodegradable external wrapping promotes favorable adaptation in an ovine vein graft model. Acta Biomaterialia. PMID 35995404 DOI: 10.1016/j.actbio.2022.08.029  0.3
2022 Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, ... ... Sayed N, et al. Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell. 185: 2387-2389. PMID 35750035 DOI: 10.1016/j.cell.2022.06.006  0.749
2022 Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, ... ... Sayed N, et al. Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell. PMID 35489334 DOI: 10.1016/j.cell.2022.04.005  0.781
2022 Sallam K, Thomas D, Gaddam S, Lopez N, Beck A, Beach L, Rogers AJ, Zhang H, Chen IY, Ameen M, Hiesinger W, Teuteberg JJ, Rhee JW, Wang KC, Sayed N, et al. Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing. Circulation. 145: 1367-1369. PMID 35467958 DOI: 10.1161/CIRCULATIONAHA.121.054317  0.759
2022 Thomas D, de Jesus Perez VA, Sayed N. An evidence appraisal of heart organoids in a dish and commensurability to human heart development in vivo. Bmc Cardiovascular Disorders. 22: 122. PMID 35317745 DOI: 10.1186/s12872-022-02543-7  0.379
2021 Sayed N, Huang Y, Nguyen K, Krejciova-Rajaniemi Z, Grawe AP, Gao T, Tibshirani R, Hastie T, Alpert A, Cui L, Kuznetsova T, Rosenberg-Hasson Y, Ostan R, Monti D, Lehallier B, et al. An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging. Nature Aging. 1: 598-615. PMID 34888528 DOI: 10.1038/s43587-021-00082-y  0.347
2021 Tran MV, Marceau E, Liu Y, Sallam K, Medina P, Liu C, Sayed N, Muller MD, Liang DH, Chen IY. Coronary Artery Vasospasm Requiring Cardiac Autotransplantation Yet Controlled With Tobacco. Jacc. Case Reports. 3: 1177-1181. PMID 34401754 DOI: 10.1016/j.jaccas.2021.03.018  0.597
2021 Liu C, Medina P, Thomas D, Chen IY, Sallam K, Sayed D, Sayed N. A protocol for transdifferentiation of human cardiac fibroblasts into endothelial cells via activation of innate immunity. Star Protocols. 2: 100556. PMID 34151292 DOI: 10.1016/j.xpro.2021.100556  0.708
2021 Huang X, Shen W, Veizades S, Liang G, Sayed N, Nguyen PK. Single-Cell Transcriptional Profiling Reveals Sex and Age Diversity of Gene Expression in Mouse Endothelial Cells. Frontiers in Genetics. 12: 590377. PMID 33679877 DOI: 10.3389/fgene.2021.590377  0.558
2021 Thomas D, Shenoy S, Sayed N. Building Multi-Dimensional Induced Pluripotent Stem Cells-Based Model Platforms to Assess Cardiotoxicity in Cancer Therapies. Frontiers in Pharmacology. 12: 607364. PMID 33679396 DOI: 10.3389/fphar.2021.607364  0.307
2021 Shah PP, Lv W, Rhoades JH, Poleshko A, Abbey D, Caporizzo MA, Linares-Saldana R, Heffler JG, Sayed N, Thomas D, Wang Q, Stanton LJ, Bedi K, Morley MP, Cappola TP, et al. Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. Cell Stem Cell. PMID 33529599 DOI: 10.1016/j.stem.2020.12.016  0.439
2021 Liu C, Ameen M, Himmati S, Thomas D, Sayed N. Generation of Human iPSCs by Protein Reprogramming and Stimulation of TLR3 Signaling. Methods in Molecular Biology (Clifton, N.J.). 2239: 153-162. PMID 33226618 DOI: 10.1007/978-1-0716-1084-8_10  0.367
2020 Sayed N, Liu C, Ameen M, Himmati F, Zhang JZ, Khanamiri S, Moonen JR, Wnorowski A, Cheng L, Rhee JW, Gaddam S, Wang KC, Sallam K, Boyd JH, Woo YJ, et al. Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy. Science Translational Medicine. 12. PMID 32727917 DOI: 10.1126/Scitranslmed.Aax9276  0.743
2020 Rhee JW, Yi H, Thomas D, Lam CK, Belbachir N, Tian L, Qin X, Malisa J, Lau E, Paik DT, Kim Y, Choi BS, Sayed N, Sallam K, Liao R, et al. Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cell Reports. 32: 107886. PMID 32668256 DOI: 10.1016/J.Celrep.2020.107886  0.768
2020 Tian L, Oikonomopoulos A, Liu C, Kitani T, Shrestha R, Chen CL, Ong SG, Smeets M, Karakikes I, Sayed N, Wu JC. Molecular Signatures of Beneficial Class Effects of Statins on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation. 141: 1208-1210. PMID 32250699 DOI: 10.1161/Circulationaha.118.035906  0.805
2020 Liu C, Ruan H, Himmati F, Zhao MT, Chen CC, Makar M, Chen IY, Sallam K, Mocarski ES, Sayed D, Sayed N. HIF1α Regulates Early Metabolic Changes due to Activation of Innate Immunity in Nuclear Reprogramming. Stem Cell Reports. 14: 192-200. PMID 32048999 DOI: 10.1016/J.Stemcr.2020.01.006  0.631
2020 Liu C, Liu Y, Chen C, Ameen M, Yang H, Shen M, Rhee JW, Chen IY, Sayed N, Wu JC. Abstract 325: The Regulation of Endothelial Function Through Hmgcr/mevalonate Pathway Mediated Yap Activity Circulation Research. 127. DOI: 10.1161/res.127.suppl_1.325  0.31
2019 Wnorowski A, Sharma A, Chen H, Wu H, Shao NY, Sayed N, Liu C, Countryman S, Stodieck LS, Rubins KH, Wu SM, Lee PHU, Wu JC. Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function. Stem Cell Reports. PMID 31708475 DOI: 10.1016/J.Stemcr.2019.10.006  0.809
2019 Sass G, Tsamo AT, Chounda GAM, Nangmo PK, Sayed N, Bozzi A, Wu JC, Nkengfack AE, Stevens DA. Vismione B Interferes with Infection of Vero Cells and Human Stem Cell-Derived Cardiomyocytes. The American Journal of Tropical Medicine and Hygiene. PMID 31571568 DOI: 10.4269/Ajtmh.19-0350  0.762
2019 Sass G, Madigan RT, Joubert LM, Bozzi A, Sayed N, Wu JC, Stevens DA. A Combination of Itraconazole and Amiodarone Is Highly Effective against Infection of Human Stem Cell-Derived Cardiomyocytes. The American Journal of Tropical Medicine and Hygiene. PMID 31219005 DOI: 10.4269/Ajtmh.19-0023  0.78
2019 Yang H, Qin X, Wang H, Zhao X, Liu Y, Wo HT, Liu C, Nishiga M, Chen H, Ge J, Sayed N, Abilez OJ, Ding D, Heilshorn SC, Li K. An In Vivo miRNA Delivery System for Restoring Infarcted Myocardium. Acs Nano. PMID 31149806 DOI: 10.1021/acsnano.9b03343  0.692
2019 Bozzi A, Sayed N, Matsa E, Sass G, Neofytou E, Clemons KV, Correa-Oliveira R, Stevens DA, Wu JC. Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi Infection. Stem Cell Reports. PMID 31105048 DOI: 10.1016/J.Stemcr.2019.04.017  0.795
2019 Zhang JZ, Termglinchan V, Shao NY, Itzhaki I, Liu C, Ma N, Tian L, Wang VY, Chang ACY, Guo H, Kitani T, Wu H, Lam CK, Kodo K, Sayed N, et al. A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles. Cell Stem Cell. PMID 30880024 DOI: 10.1016/J.Stem.2019.02.015  0.777
2019 Kitani T, Ong SG, Lam CK, Rhee JW, Zhang JZ, Oikonomopoulos A, Ma N, Tian L, Lee J, Telli ML, Witteles RM, Sharma A, Sayed N, Wu JC. Human Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Breast Cancer Patients. Circulation. PMID 30866650 DOI: 10.1161/Circulationaha.118.037357  0.774
2019 Sayed N, Ameen M, Wu JC. Personalized Medicine in Cardio-Oncology: The Role of iPSC. Cardiovascular Research. PMID 30768178 DOI: 10.1093/Cvr/Cvz024  0.499
2019 Kitani T, Ong S, Lam CK, Rhee J, Zhang JZ, Oikonomopoulos A, Ma N, Tian L, Lee J, Telli ML, Witteles RM, Sharma A, Sayed N, Wu JC. Abstract 782: Human-induced Pluripotent Stem Cell-derived Cardiomyocytes as a Model for Trastuzumab-Induced Cardiac Dysfunction Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.782  0.829
2019 Wei T", Chandy M, Chen IY, Wo H, Khanamiri S, Nishiga M, Seidl F, Sayed N, Liu C, Rhee J, Obal D, Chour T, Wu JC. Abstract 497: Studying Cardiovascular Effects of Marijuana on Healthy Individuals Using Human Derived Induced Pluripotent Stem Cells Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.497  0.553
2019 Chandy M, Sayed N, Lau E, Liu C, Wei T, Chen IY, Thomas D, Rhee J, Oh B, Pepic L, Husain M, Quertermous T, Nallamshetty S, Wu J. Abstract 402: Adiponectin Receptor 3 is Associated With Endothelial Nitric Oxide Synthase Dysfunction and Predicts Insulin Resistance in South Asians Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.402  0.607
2018 Huang NF, Serpooshan V, Morris VB, Sayed N, Pardon G, Abilez OJ, Nakayama KH, Pruitt BL, Wu SM, Yoon YS, Zhang J, Wu JC. Big bottlenecks in cardiovascular tissue engineering. Communications Biology. 1: 199. PMID 30480100 DOI: 10.1038/s42003-018-0202-8  0.372
2018 Paik DT, Tian L, Lee J, Sayed N, Chen IY, Rhee S, Rhee JW, Kim Y, Wirka RC, Buikema JW, Wu SM, Red-Horse K, Quertermous T, Wu JC. Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. Circulation Research. PMID 29986945 DOI: 10.1161/Circresaha.118.312913  0.745
2018 Ma N, Zhang J, Itzhaki I, Zhang SL, Chen H, Haddad F, Kitani T, Wilson KD, Tian L, Shrestha R, Wu H, Lam CK, Sayed N, Wu JC. Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells. Circulation. PMID 29914921 DOI: 10.1161/Circulationaha.117.032273  0.774
2018 Liu C, Oikonomopoulos A, Sayed N, Wu JC. Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond. Development (Cambridge, England). 145. PMID 29519889 DOI: 10.1242/Dev.156166  0.419
2018 Stack JP, Moslehi J, Sayed N, Wu JC. Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it? European Heart Journal. PMID 29377985 DOI: 10.1093/Eurheartj/Ehx811  0.472
2018 Liu C, Cheng L, Chen C, Sayed N. Generation of Endothelial Cells from Human Induced Pluripotent Stem Cells Bio-Protocol. 8. DOI: 10.21769/BIOPROTOC.3086  0.418
2018 Paik DT, Tian L, Lee J, Sayed N, Mishra R, Wu JC. Abstract 472: Large-Scale Single-Cell RNA-Seq Identifies Heterogeneous Populations of Human Primary and Induced Pluripotent Stem Cell-Derived Endothelial Cells Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.472  0.725
2018 Zhang JZ, Termglinchan V, Itzhaki I, Wang V, Shao N, Chang A, Ma N, Liu C, Kitani T, Sayed N, Wu H, Lam C, Blau H, Wu J. Abstract 217: TBX5 Clover2 /NKX2-5 TagRFP hiPSCs for Simultaneously Isolating Lineage-Specific Cardiovascular Cells Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.217  0.788
2018 Sayed N, Liu C, Himmati F, Zhang J, Khanamiri S, Chen H, Moonen J, Wnorowski A, Matsa E, Cheng L, Sallam K, Rabinovitch M, Wu JC. Abstract 209: Downregulation of KLF2 in the Endothelium Contributes to the Pathogenesis in LMNA-related Dilated Cardiomyopathy Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.209  0.682
2018 Sass G, Madigan R, Bozzi A, Sayed N, Wu J, Stevens D. 1357. A Combination of Itraconazole and Amiodarone Is Highly Effective Against Trypanosoma cruzi Infection of Human Stem Cell-Derived Cardiomyocytes Open Forum Infectious Diseases. 5. DOI: 10.1093/Ofid/Ofy210.1188  0.796
2018 Bouajila S, Moneghetti K, Kobayashi Y, Gomari FA, Abbasi F, Davis MM, Wu JC, Kuznetsova T, Sayed N, Haddad F. Immune Profile Of Healthy Cardiovascular Aging: Insights From A Population-Based Study And Network Modeling Journal of the American College of Cardiology. 71. DOI: 10.1016/S0735-1097(18)32198-3  0.309
2018 Kort E, Sayed N, Wu J, Jovinge S. REVERSING LMNA MUTATION PHENOTYPE IN CARDIOMYOCYTES WITH OLMESARTAN: CONNECTING MONOGENIC DISEASE TO DRUGS VIA TRANSCRIPTIONAL SIGNATURES Journal of the American College of Cardiology. 71: A897. DOI: 10.1016/S0735-1097(18)31438-4  0.376
2017 Zhao MT, Chen H, Liu Q, Shao NY, Sayed N, Wo HT, Zhang JZ, Ong SG, Liu C, Kim Y, Yang H, Chour T, Ma H, Gutierrez NM, Karakikes I, et al. Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs. Proceedings of the National Academy of Sciences of the United States of America. PMID 29203658 DOI: 10.1073/Pnas.1708991114  0.803
2017 Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, et al. High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Science Translational Medicine. 9. PMID 28202772 DOI: 10.1126/Scitranslmed.Aaf2584  0.784
2016 Matsa E, Burridge PW, Yu KH, Ahrens JH, Termglinchan V, Wu H, Liu C, Shukla P, Sayed N, Churko JM, Shao N, Woo NA, Chao AS, Gold JD, Karakikes I, et al. Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro. Cell Stem Cell. PMID 27545504 DOI: 10.1016/J.Stem.2016.07.006  0.771
2016 Sayed N, Liu C, Wu JC. Translation of Human-Induced Pluripotent Stem Cells: From Clinical Trial in a Dish to Precision Medicine. Journal of the American College of Cardiology. 67: 2161-76. PMID 27151349 DOI: 10.1016/J.Jacc.2016.01.083  0.523
2013 Wong WT, Sayed N, Cooke JP. Induced pluripotent stem cells: how they will change the practice of cardiovascular medicine. Methodist Debakey Cardiovascular Journal. 9: 206-9. PMID 24298311  0.377
2012 Wong WT, Huang NF, Botham CM, Sayed N, Cooke JP. Endothelial cells derived from nuclear reprogramming. Circulation Research. 111: 1363-75. PMID 23104878 DOI: 10.1161/Circresaha.111.247213  0.335
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