| Year |
Citation |
Score |
| 2023 |
Bagley DC, Morham SG, Kaplan J, Ward DM. Mon1a and FCHO2 are required for maintenance of Golgi architecture. Biorxiv : the Preprint Server For Biology. PMID 37461455 DOI: 10.1101/2023.07.06.547837 |
0.785 |
|
| 2020 |
Seguin A, Jia X, Earl AM, Li L, Wallace J, Qiu A, Bradley T, Shrestha R, Troadec MB, Hockin M, Titen S, Warner DE, Dowdle PT, Wohlfahrt ME, Hillas E, ... ... Kaplan J, et al. The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice. The Journal of Biological Chemistry. PMID 32518166 DOI: 10.1074/Jbc.Ra120.013229 |
0.504 |
|
| 2020 |
Li L, Bertram S, Kaplan J, Jia X, Ward DM. The mitochondrial iron exporter genes MMT1 and MMT2 in yeast are transcriptionally regulated by Aft1 and Yap1. The Journal of Biological Chemistry. PMID 31896574 DOI: 10.1074/Jbc.Ra119.011154 |
0.519 |
|
| 2018 |
Yien YY, Shi J, Chen C, Cheung JT, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon L, Palis J, ... ... Kaplan J, et al. FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity. The Journal of Biological Chemistry. PMID 30366982 DOI: 10.1074/Jbc.Ra118.002742 |
0.551 |
|
| 2018 |
Ward DM, Chen OS, Li L, Kaplan J, Bhuiyan SA, Natarajan SK, Bard M, Cox JE. Altered sterol metabolism in budding yeast affects mitochondrial iron-sulfur (Fe-S) cluster synthesis. The Journal of Biological Chemistry. PMID 29773647 DOI: 10.1074/Jbc.Ra118.001781 |
0.47 |
|
| 2018 |
Yien YY, Shi J, Chen C, Cheung J, Grillo A, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King M, Ablain J, Zon LI, Palis J, Burke M, ... ... Kaplan J, et al. Target of Erythropoietin, Fam210b, Regulates Erythroid Heme Synthesis By Control of Mitochondrial Iron Import and Regulation of Fech Activity Blood. 132: 849-849. DOI: 10.1182/Blood-2018-99-120299 |
0.551 |
|
| 2017 |
Seguin A, Takahashi-Makise N, Yien YY, Huston NC, Whitman JC, Musso G, Wallace JA, Bradley T, Bergonia H, Kafina MD, Matsumoto M, Igarashi K, Phillips JD, Paw BH, Kaplan J, et al. Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes. The Journal of Biological Chemistry. PMID 28808058 DOI: 10.1074/Jbc.M117.797415 |
0.412 |
|
| 2017 |
Li L, Kaplan J, Ward DM. The glucose sensor Snf1 and the transcription factors Msn2 and Msn4 regulate transcription of the vacuolar iron importer gene CCC1 and iron resistance in yeast. The Journal of Biological Chemistry. PMID 28760824 DOI: 10.1074/Jbc.M117.802504 |
0.5 |
|
| 2017 |
Chung J, Wittig JG, Ghamari A, Maeda M, Dailey TA, Bergonia H, Kafina MD, Coughlin EE, Minogue CE, Hebert AS, Li L, Kaplan J, Lodish HF, Bauer DE, Orkin SH, et al. Erythropoietin signaling regulates heme biosynthesis. Elife. 6. PMID 28553927 DOI: 10.7554/Elife.24767 |
0.35 |
|
| 2017 |
Yaish HM, Farrell CP, Christensen RD, MacQueen BC, Jackson LK, Trochez-Enciso J, Kaplan J, Ward DM, Salah WK, Phillips JD. Two novel mutations in TMPRSS6 associated with iron-refractory iron deficiency anemia in a mother and child. Blood Cells, Molecules & Diseases. 65: 38-40. PMID 28460265 DOI: 10.1016/J.Bcmd.2017.04.002 |
0.491 |
|
| 2016 |
MacQueen BC, Christensen RD, Ward DM, Bennett ST, O'Brien EA, Sheffield MJ, Baer VL, Snow GL, Weaver Lewis KA, Fleming RE, Kaplan J. The iron status at birth of neonates with risk factors for developing iron deficiency: a pilot study. Journal of Perinatology : Official Journal of the California Perinatal Association. PMID 27977019 DOI: 10.1038/Jp.2016.234 |
0.396 |
|
| 2015 |
Kaplan J, Ward DM. Muscle specific iron deficiency has systemic consequences. Ebiomedicine. 2: 1582-3. PMID 26870775 DOI: 10.1016/J.Ebiom.2015.10.001 |
0.496 |
|
| 2015 |
Yien YY, Chen C, Shi J, Li L, Bauer DE, Huston N, Kingsley PD, Ablain J, Zon LI, Palis J, Orkin SH, Kaplan J, Phillips JD, Lodish HF, Paw B. Fam210b Is Required for Optimal Cellular and Mitochondrial Iron Uptake during Erythroid Differentiation Blood. 126: 405-405. DOI: 10.1182/Blood.V126.23.405.405 |
0.529 |
|
| 2014 |
Yien YY, Robledo RF, Schultz IJ, Takahashi-Makise N, Gwynn B, Bauer DE, Dass A, Yi G, Li L, Hildick-Smith GJ, Cooney JD, Pierce EL, Mohler K, Dailey TA, Miyata N, ... ... Kaplan J, et al. TMEM14C is required for erythroid mitochondrial heme metabolism. The Journal of Clinical Investigation. 124: 4294-304. PMID 25157825 DOI: 10.1172/Jci76979 |
0.332 |
|
| 2014 |
Li L, Miao R, Jia X, Ward DM, Kaplan J. Expression of the yeast cation diffusion facilitators Mmt1 and Mmt2 affects mitochondrial and cellular iron homeostasis: evidence for mitochondrial iron export. The Journal of Biological Chemistry. 289: 17132-41. PMID 24798331 DOI: 10.1074/Jbc.M114.574723 |
0.537 |
|
| 2014 |
Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, ... ... Kaplan J, et al. Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria. The Journal of Biological Chemistry. 289: 7835-43. PMID 24509859 DOI: 10.1074/Jbc.M114.547778 |
0.537 |
|
| 2014 |
Ben-Othman R, Flannery AR, Miguel DC, Ward DM, Kaplan J, Andrews NW. Leishmania-mediated inhibition of iron export promotes parasite replication in macrophages. Plos Pathogens. 10: e1003901. PMID 24497831 DOI: 10.1371/Journal.Ppat.1003901 |
0.478 |
|
| 2014 |
Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, ... ... Kaplan J, et al. Erratum: Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria (Journal of Biological Chemistry (2014) 289 (7835-7843)) Journal of Biological Chemistry. 289. DOI: 10.1074/Jbc.A114.547778 |
0.506 |
|
| 2013 |
Kaplan J, Ward DM. The essential nature of iron usage and regulation. Current Biology : Cb. 23: 2325. PMID 30001585 DOI: 10.1016/J.Cub.2013.10.059 |
0.492 |
|
| 2013 |
Kaplan J, Ward DM. The essential nature of iron usage and regulation. Current Biology : Cb. 23: R642-6. PMID 23928078 DOI: 10.1016/J.Cub.2013.05.033 |
0.474 |
|
| 2013 |
Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, ... ... Kaplan J, et al. Snx3 regulates recycling of the transferrin receptor and iron assimilation. Cell Metabolism. 17: 343-52. PMID 23416069 DOI: 10.1016/J.Cmet.2013.01.013 |
0.431 |
|
| 2013 |
Paw BH, Yien YY, Robledo RF, Schultz IJ, Takahashi-Makise N, Philllips J, Miyata N, Gwynn B, Dailey TA, Pierce E, Hildick-Smith GJ, Cooney JD, Chen W, Shah DI, Hattangadi SM, ... ... Kaplan J, et al. Tmem14c Plays An Essential Role In Mitochondrial Heme Metabolism Blood. 122: 427-427. DOI: 10.1182/Blood.V122.21.427.427 |
0.428 |
|
| 2012 |
Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, ... ... Kaplan J, et al. Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature. 491: 608-12. PMID 23135403 DOI: 10.1038/Nature11536 |
0.342 |
|
| 2012 |
Li L, Miao R, Bertram S, Jia X, Ward DM, Kaplan J. A role for iron-sulfur clusters in the regulation of transcription factor Yap5-dependent high iron transcriptional responses in yeast. The Journal of Biological Chemistry. 287: 35709-21. PMID 22915593 DOI: 10.1074/Jbc.M112.395533 |
0.517 |
|
| 2012 |
De Domenico I, Lo E, Yang B, Korolnek T, Hamza I, Ward DM, Kaplan J. Retraction notice to: The role of ubiquitination in hepcidin- independent and hepcidin-dependent degradation of ferroportin (Cell Metabolism (2011) 14, (635-646) DOI: 10.1016/j.cmet.2011.09.008) Cell Metabolism. 15: 927. PMID 22866335 DOI: 10.1016/J.Cmet.2012.04.017 |
0.328 |
|
| 2012 |
De Domenico I, Vaughn MB, Paradkar PN, Lo E, Ward DM, Kaplan J. Retraction notice to: Decoupling ferritin synthesis from free cytosolic iron results in ferritin secretion (Cell Metabolism (2011) 13, (57-67) DOI: 10.1016/j.cmet.2010.12.003) Cell Metabolism. 15: 927. PMID 22866334 DOI: 10.1016/J.Cmet.2012.04.012 |
0.388 |
|
| 2012 |
Polati R, Castagna A, Bossi AM, Alberio T, De Domenico I, Kaplan J, Timperio AM, Zolla L, Gevi F, D'Alessandro A, Brunch R, Olivieri O, Girelli D. Murine macrophages response to iron. Journal of Proteomics. 76: 10-27. PMID 22835775 DOI: 10.1016/J.Jprot.2012.07.018 |
0.515 |
|
| 2012 |
Bagley DC, Paradkar PN, Kaplan J, Ward DM. Mon1a protein acts in trafficking through the secretory apparatus. The Journal of Biological Chemistry. 287: 25577-88. PMID 22665492 DOI: 10.1074/Jbc.M112.354043 |
0.781 |
|
| 2012 |
Ward DM, Kaplan J. Ferroportin-mediated iron transport: expression and regulation. Biochimica Et Biophysica Acta. 1823: 1426-33. PMID 22440327 DOI: 10.1016/J.Bbamcr.2012.03.004 |
0.526 |
|
| 2012 |
Durchfort N, Verhoef S, Vaughn MB, Shrestha R, Adam D, Kaplan J, Ward DM. The enlarged lysosomes in beige j cells result from decreased lysosome fission and not increased lysosome fusion. Traffic (Copenhagen, Denmark). 13: 108-19. PMID 21985295 DOI: 10.1111/J.1600-0854.2011.01300.X |
0.353 |
|
| 2012 |
Chen C, Santos DG, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Cooney JD, Chen W, King MJ, Schultz IJ, Yien YY, Dalton AJ, Kingsley PD, Palis J, ... ... Kaplan J, et al. SNX3 Regulates Recycling of the Transferrin Receptor and Iron Assimilation in Developing Erythrocytes* Blood. 120: 607-607. DOI: 10.1182/Blood.V120.21.607.607 |
0.555 |
|
| 2011 |
Seguin A, Ward DM, Kaplan J. Regulation of ribonucleotide reductase during iron limitation. Molecular Cell. 44: 683-4. PMID 22152471 DOI: 10.1016/J.Molcel.2011.11.011 |
0.456 |
|
| 2011 |
De Domenico I, Lo E, Yang B, Korolnek T, Hamza I, Ward DM, Kaplan J. The role of ubiquitination in hepcidin-independent and hepcidin-dependent degradation of ferroportin. Cell Metabolism. 14: 635-46. PMID 22019085 DOI: 10.1016/J.Cmet.2011.09.008 |
0.536 |
|
| 2011 |
Reeder NL, Kaplan J, Xu J, Youngquist RS, Wallace J, Hu P, Juhlin KD, Schwartz JR, Grant RA, Fieno A, Nemeth S, Reichling T, Tiesman JP, Mills T, Steinke M, et al. Zinc pyrithione inhibits yeast growth through copper influx and inactivation of iron-sulfur proteins. Antimicrobial Agents and Chemotherapy. 55: 5753-60. PMID 21947398 DOI: 10.1128/Aac.00724-11 |
0.457 |
|
| 2011 |
Li L, Jia X, Ward DM, Kaplan J. Yap5 protein-regulated transcription of the TYW1 gene protects yeast from high iron toxicity. The Journal of Biological Chemistry. 286: 38488-97. PMID 21917924 DOI: 10.1074/Jbc.M111.286666 |
0.543 |
|
| 2011 |
De Domenico I, Ward DM, Kaplan J. Hepcidin and ferroportin: the new players in iron metabolism. Seminars in Liver Disease. 31: 272-9. PMID 21901657 DOI: 10.1055/S-0031-1286058 |
0.529 |
|
| 2011 |
Wang Y, Langer NB, Shaw GC, Yang G, Li L, Kaplan J, Paw BH, Bloomer JR. Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria. Experimental Hematology. 39: 784-94. PMID 21627978 DOI: 10.1016/J.Exphem.2011.05.003 |
0.332 |
|
| 2011 |
Troadec MB, Warner D, Wallace J, Thomas K, Spangrude GJ, Phillips J, Khalimonchuk O, Paw BH, Ward DM, Kaplan J. Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria. Blood. 117: 5494-502. PMID 21310927 DOI: 10.1182/Blood-2010-11-319483 |
0.485 |
|
| 2011 |
Amigo JD, Yu M, Troadec MB, Gwynn B, Cooney JD, Lambert AJ, Chi NC, Weiss MJ, Peters LL, Kaplan J, Cantor AB, Paw BH. Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis. Molecular and Cellular Biology. 31: 1344-56. PMID 21248200 DOI: 10.1128/Mcb.01010-10 |
0.404 |
|
| 2011 |
Kaplan J, Ward DM, De Domenico I. The molecular basis of iron overload disorders and iron-linked anemias. International Journal of Hematology. 93: 14-20. PMID 21210258 DOI: 10.1007/S12185-010-0760-0 |
0.511 |
|
| 2011 |
De Domenico I, Vaughn MB, Paradkar PN, Lo E, Ward DM, Kaplan J. Decoupling ferritin synthesis from free cytosolic iron results in ferritin secretion. Cell Metabolism. 13: 57-67. PMID 21195349 DOI: 10.1016/J.Cmet.2010.12.003 |
0.522 |
|
| 2011 |
Lin H, Li L, Jia X, Ward DM, Kaplan J. Genetic and biochemical analysis of high iron toxicity in yeast: iron toxicity is due to the accumulation of cytosolic iron and occurs under both aerobic and anaerobic conditions. The Journal of Biological Chemistry. 286: 3851-62. PMID 21115478 DOI: 10.1074/Jbc.M110.190959 |
0.523 |
|
| 2011 |
Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz I, Pierce EL, Narla A, Hattangadi S, Langer N, Chen W, Dailey TA, Hurst SN, Faccenda D, Wiwczar J, Law TC, ... ... Kaplan J, et al. Mitochondrial Atpif1 Regulates Heme Synthesis in Developing Erythroblasts Blood. 118: 343-343. DOI: 10.1182/Blood.V118.21.343.343 |
0.447 |
|
| 2010 |
Troadec MB, Ward DM, Lo E, Kaplan J, De Domenico I. Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux. Blood. 116: 4657-64. PMID 20688958 DOI: 10.1182/Blood-2010-04-278614 |
0.486 |
|
| 2010 |
De Domenico I, Zhang TY, Koening CL, Branch RW, London N, Lo E, Daynes RA, Kushner JP, Li D, Ward DM, Kaplan J. Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice. The Journal of Clinical Investigation. 120: 2395-405. PMID 20530874 DOI: 10.1172/Jci42011 |
0.403 |
|
| 2010 |
Li L, Murdock G, Bagley D, Jia X, Ward DM, Kaplan J. Genetic dissection of a mitochondria-vacuole signaling pathway in yeast reveals a link between chronic oxidative stress and vacuolar iron transport. The Journal of Biological Chemistry. 285: 10232-42. PMID 20139087 DOI: 10.1074/Jbc.M109.096859 |
0.827 |
|
| 2010 |
De Domenico I, Lo E, Ward DM, Kaplan J. Human mutation D157G in ferroportin leads to hepcidin-independent binding of Jak2 and ferroportin down-regulation. Blood. 115: 2956-9. PMID 20124516 DOI: 10.1182/Blood-2009-10-251306 |
0.491 |
|
| 2010 |
De Domenico I, Ward DM, Kaplan J. Autophagy, ferritin and iron chelation. Autophagy. 6: 157. PMID 20009528 DOI: 10.4161/Auto.6.1.10587 |
0.526 |
|
| 2010 |
Shah DI, Takahasi-Makise N, Schultz I, Pierce EL, Li L, Vogin G, Brigham BS, Zhou Y, Brugnara C, Campanella M, Danial N, Ward DM, Kaplan J, Paw BH. atpif1 regulates Mitochondrial Heme Synthesis In Developing Erythroid Cells Blood. 116: 163-163. DOI: 10.1182/Blood.V116.21.163.163 |
0.496 |
|
| 2009 |
Takahashi-Makise N, Ward DM, Kaplan J. On the mechanism of iron sensing by IRP2: new players, new paradigms. Nature Chemical Biology. 5: 874-875. PMID 26190951 DOI: 10.1038/Nchembio.261 |
0.519 |
|
| 2009 |
Morrissey J, Baxter IR, Lee J, Li L, Lahner B, Grotz N, Kaplan J, Salt DE, Guerinot ML. The ferroportin metal efflux proteins function in iron and cobalt homeostasis in Arabidopsis. The Plant Cell. 21: 3326-38. PMID 19861554 DOI: 10.1105/Tpc.109.069401 |
0.517 |
|
| 2009 |
De Domenico I, Kaplan J. A new wrinkle in the fold: hepcidin links inflammation to the unfolded protein response. Cell Metabolism. 10: 245-6. PMID 19808016 DOI: 10.1016/J.Cmet.2009.09.005 |
0.345 |
|
| 2009 |
Chen W, Paradkar PN, Li L, Pierce EL, Langer NB, Takahashi-Makise N, Hyde BB, Shirihai OS, Ward DM, Kaplan J, Paw BH. Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 106: 16263-8. PMID 19805291 DOI: 10.1073/Pnas.0904519106 |
0.508 |
|
| 2009 |
Kaplan CD, Kaplan J. Iron acquisition and transcriptional regulation. Chemical Reviews. 109: 4536-52. PMID 19705827 DOI: 10.1021/Cr9001676 |
0.468 |
|
| 2009 |
De Domenico I, Ward DM, Kaplan J. Specific iron chelators determine the route of ferritin degradation. Blood. 114: 4546-51. PMID 19671920 DOI: 10.1182/Blood-2009-05-224188 |
0.52 |
|
| 2009 |
Nilsson R, Schultz IJ, Pierce EL, Soltis KA, Naranuntarat A, Ward DM, Baughman JM, Paradkar PN, Kingsley PD, Culotta VC, Kaplan J, Palis J, Paw BH, Mootha VK. Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis. Cell Metabolism. 10: 119-30. PMID 19656490 DOI: 10.1016/J.Cmet.2009.06.012 |
0.408 |
|
| 2009 |
Koening CL, Miller JC, Nelson JM, Ward DM, Kushner JP, Bockenstedt LK, Weis JJ, Kaplan J, De Domenico I. Toll-like receptors mediate induction of hepcidin in mice infected with Borrelia burgdorferi. Blood. 114: 1913-8. PMID 19587376 DOI: 10.1182/Blood-2009-03-209577 |
0.342 |
|
| 2009 |
Lin H, Burton D, Li L, Warner DE, Phillips JD, Ward DM, Kaplan J. Gain-of-function mutations identify amino acids within transmembrane domains of the yeast vacuolar transporter Zrc1 that determine metal specificity. The Biochemical Journal. 422: 273-83. PMID 19538181 DOI: 10.1042/Bj20090853 |
0.404 |
|
| 2009 |
Fernandes A, Preza GC, Phung Y, De Domenico I, Kaplan J, Ganz T, Nemeth E. The molecular basis of hepcidin-resistant hereditary hemochromatosis. Blood. 114: 437-43. PMID 19383972 DOI: 10.1182/Blood-2008-03-146134 |
0.481 |
|
| 2009 |
De Domenico I, Lo E, Ward DM, Kaplan J. Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2. Proceedings of the National Academy of Sciences of the United States of America. 106: 3800-5. PMID 19234114 DOI: 10.1073/Pnas.0900453106 |
0.452 |
|
| 2009 |
De Domenico I, Ward DM, Kaplan J. Serum ferritin regulates blood vessel formation: a role beyond iron storage. Proceedings of the National Academy of Sciences of the United States of America. 106: 1683-4. PMID 19193849 DOI: 10.1073/Pnas.0813318106 |
0.47 |
|
| 2009 |
Troadec MB, Ward DM, Kaplan J. A Tf-independent iron transport system required for organogenesis. Developmental Cell. 16: 3-4. PMID 19154711 DOI: 10.1016/J.Devcel.2008.12.013 |
0.515 |
|
| 2009 |
Paradkar PN, Zumbrennen KB, Paw BH, Ward DM, Kaplan J. Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2. Molecular and Cellular Biology. 29: 1007-16. PMID 19075006 DOI: 10.1128/Mcb.01685-08 |
0.484 |
|
| 2008 |
Silvestri L, Pagani A, Nai A, De Domenico I, Kaplan J, Camaschella C. The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin. Cell Metabolism. 8: 502-11. PMID 18976966 DOI: 10.1016/J.Cmet.2008.09.012 |
0.519 |
|
| 2008 |
Lin H, Kumánovics A, Nelson JM, Warner DE, Ward DM, Kaplan J. A single amino acid change in the yeast vacuolar metal transporters ZRC1 and COT1 alters their substrate specificity. The Journal of Biological Chemistry. 283: 33865-73. PMID 18930916 DOI: 10.1074/Jbc.M804377200 |
0.507 |
|
| 2008 |
Girelli D, De Domenico I, Bozzini C, Campostrini N, Busti F, Castagna A, Soriani N, Cremonesi L, Ferrari M, Colombari R, McVey Ward D, Kaplan J, Corrocher R. Clinical, pathological, and molecular correlates in ferroportin disease: a study of two novel mutations. Journal of Hepatology. 49: 664-71. PMID 18713659 DOI: 10.1182/Blood.V110.11.706.706 |
0.354 |
|
| 2008 |
De Domenico I, Nemeth E, Nelson JM, Phillips JD, Ajioka RS, Kay MS, Kushner JP, Ganz T, Ward DM, Kaplan J. The hepcidin-binding site on ferroportin is evolutionarily conserved. Cell Metabolism. 8: 146-56. PMID 18680715 DOI: 10.1016/J.Cmet.2008.07.002 |
0.408 |
|
| 2008 |
Kieffer C, Skalicky JJ, Morita E, De Domenico I, Ward DM, Kaplan J, Sundquist WI. Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding. Developmental Cell. 15: 62-73. PMID 18606141 DOI: 10.1016/J.Devcel.2008.05.014 |
0.339 |
|
| 2008 |
Paradkar PN, De Domenico I, Durchfort N, Zohn I, Kaplan J, Ward DM. Iron depletion limits intracellular bacterial growth in macrophages. Blood. 112: 866-74. PMID 18369153 DOI: 10.1182/Blood-2007-12-126854 |
0.447 |
|
| 2008 |
Kumánovics A, Chen OS, Li L, Bagley D, Adkins EM, Lin H, Dingra NN, Outten CE, Keller G, Winge D, Ward DM, Kaplan J. Identification of FRA1 and FRA2 as genes involved in regulating the yeast iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis. The Journal of Biological Chemistry. 283: 10276-86. PMID 18281282 DOI: 10.1074/Jbc.M801160200 |
0.824 |
|
| 2008 |
Keel SB, Doty RT, Yang Z, Quigley JG, Chen J, Knoblaugh S, Kingsley PD, De Domenico I, Vaughn MB, Kaplan J, Palis J, Abkowitz JL. A heme export protein is required for red blood cell differentiation and iron homeostasis. Science (New York, N.Y.). 319: 825-8. PMID 18258918 DOI: 10.1126/Science.1151133 |
0.521 |
|
| 2008 |
Li L, Bagley D, Ward DM, Kaplan J. Yap5 is an iron-responsive transcriptional activator that regulates vacuolar iron storage in yeast. Molecular and Cellular Biology. 28: 1326-37. PMID 18070921 DOI: 10.1128/Mcb.01219-07 |
0.825 |
|
| 2008 |
De Domenico I, McVey Ward D, Kaplan J. Regulation of iron acquisition and storage: consequences for iron-linked disorders. Nature Reviews. Molecular Cell Biology. 9: 72-81. PMID 17987043 DOI: 10.1038/Nrm2295 |
0.513 |
|
| 2008 |
Chen W, Li L, Langer NB, Paradkar PN, Schultz IJ, Hyde BB, Shirihai OS, Kaplan J, Paw BH. Abcb10 Physically Interacts with Mitoferrin1 to Enhance Its Stability for Heme Synthesis in the Erythroid Mitochondria Blood. 112: 530-530. DOI: 10.1182/Blood.V112.11.530.530 |
0.466 |
|
| 2008 |
Domenico ID, Ward DM, Kushner JP, Kaplan J. Iron Chelation by Deferoxamine Induces Autophagy Blood. 112: 117-117. DOI: 10.1182/Blood.V112.11.117.117 |
0.521 |
|
| 2008 |
Askwith C, Kaplan J. The biochemistry and molecular biology of iron metabolism in yeast Iron Metabolism: Inorganic Biochemistry and Regulatory Mechanisms. 51-63. DOI: 10.1002/9783527613700.ch04 |
0.7 |
|
| 2007 |
De Domenico I, Vaughn MB, Yoon D, Kushner JP, Ward DM, Kaplan J. Zebrafish as a model for defining the functional impact of mammalian ferroportin mutations. Blood. 110: 3780-3. PMID 17726163 DOI: 10.1182/Blood-2007-07-100248 |
0.471 |
|
| 2007 |
Wang F, Paradkar PN, Custodio AO, McVey Ward D, Fleming MD, Campagna D, Roberts KA, Boyartchuk V, Dietrich WF, Kaplan J, Andrews NC. Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice. Nature Genetics. 39: 1025-32. PMID 17632513 DOI: 10.1038/Ng2059 |
0.504 |
|
| 2007 |
De Domenico I, Ward DM, Kaplan J. Hepcidin regulation: ironing out the details. The Journal of Clinical Investigation. 117: 1755-8. PMID 17607352 DOI: 10.1172/Jci32701 |
0.502 |
|
| 2007 |
De Domenico I, Ward DM, di Patti MC, Jeong SY, David S, Musci G, Kaplan J. Ferroxidase activity is required for the stability of cell surface ferroportin in cells expressing GPI-ceruloplasmin. The Embo Journal. 26: 2823-31. PMID 17541408 DOI: 10.1038/Sj.Emboj.7601735 |
0.535 |
|
| 2007 |
Möhlig H, Mathieu S, Thon L, Frederiksen MC, Ward DM, Kaplan J, Schütze S, Kabelitz D, Adam D. The WD repeat protein FAN regulates lysosome size independent from abnormal downregulation/membrane recruitment of protein kinase C. Experimental Cell Research. 313: 2703-18. PMID 17512928 DOI: 10.1016/J.Yexcr.2007.04.020 |
0.35 |
|
| 2007 |
De Domenico I, Ward DM, Langelier C, Vaughn MB, Nemeth E, Sundquist WI, Ganz T, Musci G, Kaplan J. The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Molecular Biology of the Cell. 18: 2569-78. PMID 17475779 DOI: 10.1091/Mbc.E07-01-0060 |
0.452 |
|
| 2007 |
Zohn IE, De Domenico I, Pollock A, Ward DM, Goodman JF, Liang X, Sanchez AJ, Niswander L, Kaplan J. The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease. Blood. 109: 4174-80. PMID 17289807 DOI: 10.1182/Blood-2007-01-066068 |
0.397 |
|
| 2007 |
De Domenico I, Ward DM, Musci G, Kaplan J. Evidence for the multimeric structure of ferroportin. Blood. 109: 2205-9. PMID 17077321 DOI: 10.1182/Blood-2006-06-032516 |
0.488 |
|
| 2007 |
Keel SB, Doty RT, Knoblaugh S, Domenico ID, Kaplan J, Abkowitz JL. A Heme Export Protein Is Required for Red Cell Differentiation and Iron Homeostasis. Blood. 110: 2658-2658. DOI: 10.1182/Blood.V110.11.2658.2658 |
0.473 |
|
| 2006 |
De Domenico I, Vaughn MB, Li L, Bagley D, Musci G, Ward DM, Kaplan J. Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome. The Embo Journal. 25: 5396-404. PMID 17082767 DOI: 10.1038/Sj.Emboj.7601409 |
0.826 |
|
| 2006 |
Kim SA, Punshon T, Lanzirotti A, Li L, Alonso JM, Ecker JR, Kaplan J, Guerinot ML. Localization of iron in Arabidopsis seed requires the vacuolar membrane transporter VIT1. Science (New York, N.Y.). 314: 1295-8. PMID 17082420 DOI: 10.1126/Science.1132563 |
0.493 |
|
| 2006 |
Davis-Kaplan SR, Compton MA, Flannery AR, Ward DM, Kaplan J, Stevens TH, Graham LA. PKR1 encodes an assembly factor for the yeast V-type ATPase. The Journal of Biological Chemistry. 281: 32025-35. PMID 16926153 DOI: 10.1074/Jbc.M606451200 |
0.397 |
|
| 2006 |
De Domenico I, McVey Ward D, Nemeth E, Ganz T, Corradini E, Ferrara F, Musci G, Pietrangelo A, Kaplan J. Molecular and clinical correlates in iron overload associated with mutations in ferroportin. Haematologica. 91: 1092-5. PMID 16885049 |
0.394 |
|
| 2006 |
Kumánovics A, Poruk KE, Osborn KA, Ward DM, Kaplan J. YKE4 (YIL023C) encodes a bidirectional zinc transporter in the endoplasmic reticulum of Saccharomyces cerevisiae. The Journal of Biological Chemistry. 281: 22566-74. PMID 16760462 DOI: 10.1074/Jbc.M604730200 |
0.415 |
|
| 2006 |
Kaplan J, McVey Ward D, Crisp RJ, Philpott CC. Iron-dependent metabolic remodeling in S. cerevisiae. Biochimica Et Biophysica Acta. 1763: 646-51. PMID 16697062 DOI: 10.1016/J.Bbamcr.2006.03.008 |
0.511 |
|
| 2006 |
Runkel F, Büssow H, Seburn KL, Cox GA, Ward DM, Kaplan J, Franz T. Grey, a novel mutation in the murine Lyst gene, causes the beige phenotype by skipping of exon 25. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 203-10. PMID 16518687 DOI: 10.1007/S00335-005-0015-1 |
0.321 |
|
| 2006 |
Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, ... ... Kaplan J, et al. Mitoferrin is essential for erythroid iron assimilation. Nature. 440: 96-100. PMID 16511496 DOI: 10.1038/Nature04512 |
0.536 |
|
| 2006 |
Crisp RJ, Adkins EM, Kimmel E, Kaplan J. Recruitment of Tup1p and Cti6p regulates heme-deficient expression of Aft1p target genes. The Embo Journal. 25: 512-21. PMID 16437160 DOI: 10.1038/Sj.Emboj.7600961 |
0.47 |
|
| 2006 |
De Domenico I, Ward DM, Musci G, Kaplan J. Iron overload due to mutations in ferroportin. Haematologica. 91: 92-5. PMID 16434376 DOI: 10.3324/%%X |
0.52 |
|
| 2006 |
Shaw GC, Langer NB, Wang Y, Li L, Kaplan J, Bloomer JR, Paw BH. Abnormal Expression of Human Mitoferrin (SLC25A37) Is Associated with a Variant of Erythropoietic Protoporphyria. Blood. 108: 3-3. DOI: 10.1182/Blood.V108.11.3.3 |
0.481 |
|
| 2006 |
Paw BH, Gwynn B, Langer NB, Shaw GC, Lambert AJ, Boyer LA, Li L, Stolte J, Robledo RF, Sahr KE, Schlaeger TM, Hentze MW, Muckenthaler MU, Kaplan J, Peters LL. Targeted Disruption of the Mouse Mitoferrin (Slc25A37) Mitochondrial Solute Carrier Results in Defective Primitive and Definitive Erythropoiesis. Blood. 108: 265-265. DOI: 10.1182/Blood.V108.11.265.265 |
0.428 |
|
| 2005 |
Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmid B, Schmidt B, Paw BH, Shaw GC, Kingsley P, Palis J, ... ... Kaplan J, et al. Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature. 436: 1035-39. PMID 16110529 DOI: 10.1038/Nature03887 |
0.475 |
|
| 2005 |
Kaplan CD, Kaplan J. Regulatory oversight of the iron trade: posttranscriptional regulation in yeast. Cell Metabolism. 2: 4-6. PMID 16054093 DOI: 10.1016/J.Cmet.2005.06.008 |
0.514 |
|
| 2005 |
De Domenico I, Ward DM, Nemeth E, Vaughn MB, Musci G, Ganz T, Kaplan J. The molecular basis of ferroportin-linked hemochromatosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 8955-60. PMID 15956209 DOI: 10.1073/Pnas.0503804102 |
0.476 |
|
| 2005 |
Felice MR, De Domenico I, Li L, Ward DM, Bartok B, Musci G, Kaplan J. Post-transcriptional regulation of the yeast high affinity iron transport system. The Journal of Biological Chemistry. 280: 22181-90. PMID 15817488 DOI: 10.1074/Jbc.M414663200 |
0.552 |
|
| 2005 |
Ward DM, Vaughn MB, Shiflett SL, White PL, Pollock AL, Hill J, Schnegelberger R, Sundquist WI, Kaplan J. The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. The Journal of Biological Chemistry. 280: 10548-55. PMID 15644320 DOI: 10.1074/Jbc.M413734200 |
0.767 |
|
| 2005 |
Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmid B, Paw BH, Shaw GC, Kingsley P, Palis J, Schubert H, ... ... Kaplan J, et al. Erratum: Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis (Nature (2005) 436 (1035-1039)) Nature. 437. DOI: 10.1038/Nature04218 |
0.322 |
|
| 2004 |
Huynh C, Roth D, Ward DM, Kaplan J, Andrews NW. Defective lysosomal exocytosis and plasma membrane repair in Chediak-Higashi/beige cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 16795-800. PMID 15557559 DOI: 10.1073/Pnas.0405905101 |
0.336 |
|
| 2004 |
Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science (New York, N.Y.). 306: 2090-3. PMID 15514116 DOI: 10.1126/Science.1104742 |
0.506 |
|
| 2004 |
Shiflett SL, Vaughn MB, Huynh D, Kaplan J, Ward DM. Bph1p, the Saccharomyces cerevisiae homologue of CHS1/beige, functions in cell wall formation and protein sorting. Traffic (Copenhagen, Denmark). 5: 700-10. PMID 15296494 DOI: 10.1111/J.1600-0854.2004.00213.X |
0.78 |
|
| 2004 |
Li L, Kaplan J. A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism. The Journal of Biological Chemistry. 279: 33653-61. PMID 15161905 DOI: 10.1074/Jbc.M403146200 |
0.539 |
|
| 2004 |
Chen OS, Crisp RJ, Valachovic M, Bard M, Winge DR, Kaplan J. Transcription of the yeast iron regulon does not respond directly to iron but rather to iron-sulfur cluster biosynthesis. The Journal of Biological Chemistry. 279: 29513-8. PMID 15123701 DOI: 10.1074/Jbc.M403209200 |
0.521 |
|
| 2004 |
Harris ZL, Davis-Kaplan SR, Gitlin JD, Kaplan J. A fungal multicopper oxidase restores iron homeostasis in aceruloplasminemia. Blood. 103: 4672-3. PMID 14739215 DOI: 10.1182/Blood-2003-11-4060 |
0.54 |
|
| 2004 |
Shiflett SL, Ward DM, Huynh D, Vaughn MB, Simmons JC, Kaplan J. Characterization of Vta1p, a class E Vps protein in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 279: 10982-90. PMID 14701806 DOI: 10.1074/Jbc.M312669200 |
0.787 |
|
| 2004 |
Davis-Kaplan SR, Ward DM, Shiflett SL, Kaplan J. Genome-wide analysis of iron-dependent growth reveals a novel yeast gene required for vacuolar acidification. The Journal of Biological Chemistry. 279: 4322-9. PMID 14594803 DOI: 10.1074/Jbc.M310680200 |
0.83 |
|
| 2004 |
Wingert RA, Barut B, Foott H, Fraenkel P, Dooley K, Kingsley P, Palis J, Shubert H, Chen O, Kaplan J, Zon LI. The Zebrafish Hypochromic Mutant [iItalic]Shiraz[/iItalic] Encodes a Novel Mitochondrial Glutaredoxin That Establishes a Link between Heme and Fe/S Production. Blood. 104: 51-51. DOI: 10.1182/Blood.V104.11.51.51 |
0.488 |
|
| 2003 |
Crisp RJ, Pollington A, Galea C, Jaron S, Yamaguchi-Iwai Y, Kaplan J. Inhibition of heme biosynthesis prevents transcription of iron uptake genes in yeast. The Journal of Biological Chemistry. 278: 45499-506. PMID 12928433 DOI: 10.1074/Jbc.M307229200 |
0.537 |
|
| 2003 |
Li L, Vulpe CD, Kaplan J. Functional studies of hephaestin in yeast: evidence for multicopper oxidase activity in the endocytic pathway. The Biochemical Journal. 375: 793-8. PMID 12921533 DOI: 10.1042/Bj20030866 |
0.566 |
|
| 2003 |
Ward DM, Shiflett SL, Huynh D, Vaughn MB, Prestwich G, Kaplan J. Use of expression constructs to dissect the functional domains of the CHS/beige protein: identification of multiple phenotypes. Traffic (Copenhagen, Denmark). 4: 403-15. PMID 12753649 DOI: 10.1034/J.1600-0854.2003.00093.X |
0.776 |
|
| 2003 |
Tuttle MS, Radisky D, Li L, Kaplan J. A dominant allele of PDR1 alters transition metal resistance in yeast. The Journal of Biological Chemistry. 278: 1273-80. PMID 12411429 DOI: 10.1074/Jbc.M209631200 |
0.5 |
|
| 2002 |
Chen OS, Hemenway S, Kaplan J. Genetic analysis of iron citrate toxicity in yeast: implications for mammalian iron homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 99: 16922-7. PMID 12471153 DOI: 10.1073/Pnas.232392299 |
0.531 |
|
| 2002 |
Kaplan J. Mechanisms of cellular iron acquisition: another iron in the fire. Cell. 111: 603-6. PMID 12464171 DOI: 10.1016/S0092-8674(02)01164-9 |
0.499 |
|
| 2002 |
Kaplan J. Strategy and tactics in the evolution of iron acquisition. Seminars in Hematology. 39: 219-26. PMID 12382196 DOI: 10.1053/Shem.2002.35631 |
0.497 |
|
| 2002 |
Chen OS, Hemenway S, Kaplan J. Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: evidence that Yfh1p affects Fe-S cluster synthesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 12321-6. PMID 12221295 DOI: 10.1073/Pnas.192449599 |
0.445 |
|
| 2002 |
Van Ho A, Ward DM, Kaplan J. Transition metal transport in yeast. Annual Review of Microbiology. 56: 237-61. PMID 12142483 DOI: 10.1146/Annurev.Micro.56.012302.160847 |
0.335 |
|
| 2002 |
Ward DM, Shiflett SL, Kaplan J. Chediak-Higashi syndrome: a clinical and molecular view of a rare lysosomal storage disorder. Current Molecular Medicine. 2: 469-77. PMID 12125812 DOI: 10.2174/1566524023362339 |
0.766 |
|
| 2002 |
Shiflett SL, Kaplan J, Ward DM. Chediak-Higashi Syndrome: a rare disorder of lysosomes and lysosome related organelles. Pigment Cell Research / Sponsored by the European Society For Pigment Cell Research and the International Pigment Cell Society. 15: 251-7. PMID 12100490 DOI: 10.1034/J.1600-0749.2002.02038.X |
0.77 |
|
| 2002 |
Miranda CJ, Santos MM, Ohshima K, Smith J, Li L, Bunting M, Cossée M, Koenig M, Sequeiros J, Kaplan J, Pandolfo M. Frataxin knockin mouse. Febs Letters. 512: 291-7. PMID 11852098 DOI: 10.1016/S0014-5793(02)02251-2 |
0.437 |
|
| 2002 |
Kaplan J. Spinocerebellar ataxias due to mitochondrial defects. Neurochemistry International. 40: 553-7. PMID 11850112 DOI: 10.1016/S0197-0186(01)00127-9 |
0.387 |
|
| 2001 |
Chen OS, Kaplan J. YFH1-mediated iron homeostasis is independent of mitochondrial respiration. Febs Letters. 509: 131-4. PMID 11734220 DOI: 10.1016/S0014-5793(01)03137-4 |
0.444 |
|
| 2001 |
Ardon O, Bussey H, Philpott C, Ward DM, Davis-Kaplan S, Verroneau S, Jiang B, Kaplan J. Identification of a Candida albicans ferrichrome transporter and its characterization by expression in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 276: 43049-55. PMID 11562378 DOI: 10.1074/Jbc.M108701200 |
0.522 |
|
| 2001 |
Ward DM, Radisky D, Scullion MA, Tuttle MS, Vaughn M, Kaplan J. hVPS41 Is Expressed in Multiple Isoforms and Can Associate with Vesicles through a RING-H2 Finger Motif Experimental Cell Research. 267: 126-134. PMID 11412045 DOI: 10.1006/Excr.2001.5244 |
0.364 |
|
| 2001 |
Li L, Chen OS, McVey Ward D, Kaplan J. CCC1 is a transporter that mediates vacuolar iron storage in yeast. The Journal of Biological Chemistry. 276: 29515-9. PMID 11390404 DOI: 10.1074/Jbc.M103944200 |
0.529 |
|
| 2001 |
Li L, Kaplan J. The yeast gene MSC2, a member of the cation diffusion facilitator family, affects the cellular distribution of zinc. Journal of Biological Chemistry. 276: 5036-5043. PMID 11058603 DOI: 10.1074/Jbc.M008969200 |
0.374 |
|
| 2000 |
Ward DM, Griffiths GM, Stinchcombe JC, Kaplan J. Analysis of the lysosomal storage disease Chediak-Higashi syndrome. Traffic (Copenhagen, Denmark). 1: 816-22. PMID 11208072 DOI: 10.1034/J.1600-0854.2000.011102.X |
0.304 |
|
| 2000 |
Ward DM, Pevsner J, Scullion MA, Vaughn M, Kaplan J. Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages. Molecular Biology of the Cell. 11: 2327-33. PMID 10888671 DOI: 10.1091/Mbc.11.7.2327 |
0.332 |
|
| 2000 |
Yun CW, Ferea T, Rashford J, Ardon O, Brown PO, Botstein D, Kaplan J, Philpott CC. Desferrioxamine-mediated iron uptake in Saccharomyces cerevisiae. Evidence for two pathways of iron uptake Journal of Biological Chemistry. 275: 10709-10715. PMID 10744769 DOI: 10.1074/Jbc.275.14.10709 |
0.556 |
|
| 2000 |
Chen OS, Kaplan J. CCC1 suppresses mitochondrial damage in the yeast model of Friedreich's ataxia by limiting mitochondrial iron accumulation. The Journal of Biological Chemistry. 275: 7626-32. PMID 10713071 DOI: 10.1074/Jbc.275.11.7626 |
0.53 |
|
| 2000 |
Kaplan J, Kushner JP. Mining the genome for iron Nature. 403: 711-713. PMID 10693783 DOI: 10.1038/35001691 |
0.511 |
|
| 1999 |
Kaplan J. Friedreich's ataxia is a mitochondrial disorder Proceedings of the National Academy of Sciences of the United States of America. 96: 10948-10949. PMID 10500103 DOI: 10.1073/Pnas.96.20.10948 |
0.32 |
|
| 1999 |
Radisky DC, Babcock MC, Kaplan J. The yeast frataxin homologue mediates mitochondrial iron efflux. Evidence for a mitochondrial iron cycle. The Journal of Biological Chemistry. 274: 4497-9. PMID 9988680 DOI: 10.1074/Jbc.274.8.4497 |
0.464 |
|
| 1999 |
Radisky D, Kaplan J. Regulation of transition metal transport across the yeast plasma membrane. Journal of Biological Chemistry. 274: 4481-4484. PMID 9988676 DOI: 10.1074/Jbc.274.8.4481 |
0.448 |
|
| 1998 |
Davis-Kaplan SR, Askwith CC, Bengtzen AC, Radisky D, Kaplan J. Chloride is an allosteric effector of copper assembly for the yeast multicopper oxidase Fet3p: an unexpected role for intracellular chloride channels. Proceedings of the National Academy of Sciences of the United States of America. 95: 13641-5. PMID 9811853 DOI: 10.1073/Pnas.95.23.13641 |
0.66 |
|
| 1998 |
Radisky DC, Kaplan J. Iron in cytosolic ferritin can be recycled through lysosomal degradation in human fibroblasts Biochemical Journal. 336: 201-205. PMID 9806901 DOI: 10.1042/Bj3360201 |
0.525 |
|
| 1998 |
Askwith CC, Kaplan J. Site-directed mutagenesis of the yeast multicopper oxidase Fet3p. The Journal of Biological Chemistry. 273: 22415-9. PMID 9712864 DOI: 10.1074/Jbc.273.35.22415 |
0.758 |
|
| 1998 |
Li L, Kaplan J. Defects in the Yeast High Affinity Iron Transport System Result in Increased Metal Sensitivity because of the Increased Expression of Transporters with a Broad Transition Metal Specificity Journal of Biological Chemistry. 273: 22181-22187. PMID 9712830 DOI: 10.1074/Jbc.273.35.22181 |
0.38 |
|
| 1998 |
Askwith C, Kaplan J. Iron and copper transport in yeast and its relevance to human disease Trends in Biochemical Sciences. 23: 135-138. PMID 9584616 DOI: 10.1016/S0968-0004(98)01192-X |
0.733 |
|
| 1997 |
Perou CM, Leslie JD, Green W, Li L, Ward DM, Kaplan J. The Beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic protein. The Journal of Biological Chemistry. 272: 29790-4. PMID 9368050 DOI: 10.1074/Jbc.272.47.29790 |
0.382 |
|
| 1997 |
Li L, Kaplan J. Characterization of Two Homologous Yeast Genes That Encode Mitochondrial Iron Transporters Journal of Biological Chemistry. 272: 28485-28493. PMID 9353309 DOI: 10.1074/Jbc.272.45.28485 |
0.566 |
|
| 1997 |
Ward DM, Leslie JD, Kaplan J. Homotypic lysosome fusion in macrophages: analysis using an in vitro assay. The Journal of Cell Biology. 139: 665-73. PMID 9348283 DOI: 10.1083/Jcb.139.3.665 |
0.324 |
|
| 1997 |
Li L, Kaplan J. Alteration in the organ distribution of iron by truncated transferrin: implications for iron chelation therapy Journal of Laboratory and Clinical Medicine. 130: 271-277. PMID 9341986 DOI: 10.1016/S0022-2143(97)90021-4 |
0.465 |
|
| 1997 |
Babcock M, de Silva D, Oaks R, Davis-Kaplan S, Jiralerspong S, Montermini L, Pandolfo M, Kaplan J. Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin. Science (New York, N.Y.). 276: 1709-12. PMID 9180083 DOI: 10.1126/Science.276.5319.1709 |
0.499 |
|
| 1997 |
Silva Dd, Davis-Kaplan S, Fergestad J, Kaplan J. Purification and characterization of Fet3 protein, a yeast homologue of ceruloplasmin. Journal of Biological Chemistry. 272: 14208-14213. PMID 9162052 DOI: 10.1074/Jbc.272.22.14208 |
0.502 |
|
| 1997 |
Radisky DC, Snyder WB, Emr SD, Kaplan J. Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast. Proceedings of the National Academy of Sciences of the United States of America. 94: 5662-6. PMID 9159129 DOI: 10.1073/Pnas.94.11.5662 |
0.472 |
|
| 1997 |
Askwith C, Kaplan J. An oxidase-permease-based iron transport system in Schizosaccharomyces pombe and its expression in Saccharomyces cerevisiae Journal of Biological Chemistry. 272: 401-405. PMID 8995275 DOI: 10.1074/Jbc.272.1.401 |
0.749 |
|
| 1996 |
Askwith CC, de Silva D, Kaplan J. Molecular biology of iron acquisition in Saccharomyces cerevisiae. Molecular Microbiology. 20: 27-34. PMID 8861201 DOI: 10.1111/J.1365-2958.1996.Tb02485.X |
0.751 |
|
| 1996 |
Taraska T, Ward DM, Ajioka RS, Wyrick PB, Davis-Kaplan SR, Davis CH, Kaplan J. The late chlamydial inclusion membrane is not derived from the endocytic pathway and is relatively deficient in host proteins. Infection and Immunity. 64: 3713-27. PMID 8751921 DOI: 10.1128/Iai.64.9.3713-3727.1996 |
0.331 |
|
| 1996 |
Perou CM, Moore KJ, Nagle DL, Misumi DJ, Woolf EA, McGrail SH, Holmgren L, Brody TH, Dussault BJ, Monroe CA, Duyk GM, Pryor RJ, Li L, Justice MJ, Kaplan J. Identification of the murine beige gene by YAC complementation and positional cloning Nature Genetics. 13: 303-309. PMID 8673129 DOI: 10.1038/Ng0796-303 |
0.356 |
|
| 1996 |
Li L, Kaplan J. Characterization of Yeast Methyl Sterol Oxidase (ERG25) and Identification of a Human Homologue Journal of Biological Chemistry. 271: 16927-16933. PMID 8663358 DOI: 10.1074/Jbc.271.28.16927 |
0.539 |
|
| 1996 |
Perou CM, Justice MJ, Pryor RJ, Kaplan J. Complementation of the beige mutation in cultured cells by episomally replicating murine yeast artificial chromosomes Proceedings of the National Academy of Sciences of the United States of America. 93: 5905-5909. PMID 8650191 DOI: 10.1073/Pnas.93.12.5905 |
0.326 |
|
| 1996 |
Kaplan J, O'Halloran TV. Iron metabolism in eukaryotes: Mars and Venus at it again. Science (New York, N.Y.). 271: 1510-2. PMID 8599104 DOI: 10.1126/Science.271.5255.1510 |
0.502 |
|
| 1996 |
de Silva DM, Askwith CC, Kaplan J. Molecular mechanisms of iron uptake in eukaryotes. Physiological Reviews. 76: 31-47. PMID 8592731 DOI: 10.1152/Physrev.1996.76.1.31 |
0.757 |
|
| 1995 |
De Silva DM, Askwith CC, Eide D, Kaplan J. The FET3 gene product required for high affinity iron transport in yeast is a cell surface ferroxidase. The Journal of Biological Chemistry. 270: 1098-101. PMID 7836366 DOI: 10.1074/Jbc.270.3.1098 |
0.754 |
|
| 1995 |
Ward DM, Perou CM, Lloyd M, Kaplan J. "Synchronized" endocytosis and intracellular sorting in alveolar macrophages: The early sorting endosome Is a transient organelle Journal of Cell Biology. 129: 1229-1240. PMID 7775570 DOI: 10.1083/Jcb.129.5.1229 |
0.332 |
|
| 1994 |
Askwith C, Eide D, Van Ho A, Bernard PS, Li L, Davis-Kaplan S, Sipe DM, Kaplan J. The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake Cell. 76: 403-410. PMID 8293473 DOI: 10.1016/0092-8674(94)90346-8 |
0.765 |
|
| 1994 |
Dancis A, Yuan DS, Haile D, Askwith C, Eide D, Moehle C, Kaplan J, Klausner RD. Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport. Cell. 76: 393-402. PMID 8293472 DOI: 10.1016/0092-8674(94)90345-X |
0.757 |
|
| 1994 |
Jordan I, Kaplan J. The mammalian transferrin-independent iron transport system may involve a surface ferrireductase activity Biochemical Journal. 302: 875-879. PMID 7945215 DOI: 10.1042/Bj3020875 |
0.525 |
|
| 1993 |
Greene JR, Brown NH, DiDomenico BJ, Kaplan J, Eide DJ. The GEF1 gene of Saccharomyces cerevisiae encodes an integral membrane protein; mutations in which have effects on respiration and iron-limited growth. Molecular & General Genetics : Mgg. 241: 542-53. PMID 7505388 DOI: 10.1007/Bf00279896 |
0.537 |
|
| 1991 |
Buys SS, Martin CB, Eldridge M, Kushner JP, Kaplan J. Iron absorption in hypotransferrinemic mice. Blood. 78: 3288-3290. DOI: 10.1182/Blood.V78.12.3288.3288 |
0.472 |
|
| 1990 |
Kaplan J, Ward DM. Movement of receptors and ligands through the endocytic apparatus in alveolar macrophages. American Journal of Physiology-Lung Cellular and Molecular Physiology. 258. PMID 2163207 DOI: 10.1152/Ajplung.1990.258.6.L263 |
0.329 |
|
| 1989 |
Edwards CQ, Griffen LM, Kaplan J, Kushner JP. Twenty-four hour variation of transferrin saturation in treated and untreated haemochromatosis homozygotes. Journal of Internal Medicine. 226: 373-379. PMID 2681514 DOI: 10.1111/J.1365-2796.1989.Tb01411.X |
0.364 |
|
| 1989 |
Huggenvik J, Craven C, Idzerda R, Bernstein S, Kaplan J, McKnight G. A splicing defect in the mouse transferrin gene leads to congenital atransferrinemia Blood. 74: 482-486. DOI: 10.1182/Blood.V74.1.482.Bloodjournal741482 |
0.361 |
|
| 1988 |
Kaplan J, Craven C, Alexander J, Kushner J, Lamb J, Bernstein S. Regulation of the Distribution of Tissue Iron Annals of the New York Academy of Sciences. 526: 124-135. PMID 3291677 DOI: 10.1111/J.1749-6632.1988.Tb55498.X |
0.425 |
|
| 1988 |
Novak JM, Cala PM, McVey Ward D, Buys SS, Kaplan J. Regulatory volume decrease in alveolar macrophages: Cation loss is not correlated with changes in membrane recycling Journal of Cellular Physiology. 137: 243-250. PMID 3192616 DOI: 10.1002/Jcp.1041370206 |
0.303 |
|
| 1987 |
Craven CM, Alexander J, Eldridge M, Kushner JP, Bernstein S, Kaplan J. Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosis. Proceedings of the National Academy of Sciences of the United States of America. 84: 3457-3461. PMID 3472216 DOI: 10.1073/Pnas.84.10.3457 |
0.469 |
|
| 1987 |
Ward JH, Kaplan J. Receptor assay with radiolabeled transferrin. Methods in Enzymology. 147: 247-252. PMID 3312941 DOI: 10.1016/0076-6879(87)47115-2 |
0.33 |
|
| 1987 |
Buys SS, Kaplan J. Effect of phagocytosis on receptor distribution and endocytic activity in macrophages. Journal of Cellular Physiology. 131: 442-449. PMID 3036889 DOI: 10.1002/Jcp.1041310317 |
0.317 |
|
| 1987 |
Lamb JE, Craven CM, Ward JH, Kushner JP, Kaplan J. Recycling Of Reticuloendothelial Iron In Vivo In The Absence Of Apotransferrin Pediatric Research. 21: 301-301. DOI: 10.1203/00006450-198704010-00801 |
0.481 |
|
| 1982 |
Ward JH, Kushner JP, Kaplan J. Transferrin receptors of human fibroblasts. Analysis of receptor properties and regulation. Biochemical Journal. 208: 19-26. PMID 6297460 DOI: 10.1042/Bj2080019 |
0.354 |
|
| 1977 |
Tanzer ML, Rowland FN, Murray LW, Kaplan J. Inhibitory effects of tunicamycin on procollagen biosynthesis and secretion. Biochimica Et Biophysica Acta. 500: 187-96. PMID 562681 DOI: 10.1016/0304-4165(77)90058-7 |
0.341 |
|
| 1976 |
Kaplan J. Cell contact induces an increase in pinocytotic rate in cultured epithelial cells Nature. 263: 596-597. PMID 185520 DOI: 10.1038/263596A0 |
0.3 |
|
| 1975 |
Kaplan J, Moskowitz M. Studies on the turnover of plasma membranes in cultured mammalian cells. II. Demonstration of heterogeneous rates of turnover for plasma membrane proteins and glycoproteins. Biochimica Et Biophysica Acta. 389: 306-13. PMID 1169981 DOI: 10.1016/0005-2736(75)90323-5 |
0.512 |
|
| 1975 |
Kaplan J, Moskowitz M. Studies on the turnover of plasma membranes in cultured mammalina cells. I. Rates of synthesis and degradation of plasma membrane proteins and carbohydrates. Biochimica Et Biophysica Acta. 389: 290-305. PMID 1169980 DOI: 10.1016/0005-2736(75)90322-3 |
0.512 |
|
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