| Year |
Citation |
Score |
| 2015 |
Blaszczyk M, Harmer NJ, Chirgadze DY, Ascher DB, Blundell TL. Achieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors. Progress in Biophysics and Molecular Biology. PMID 25957048 DOI: 10.1016/j.pbiomolbio.2015.04.007 |
0.629 |
|
| 2011 |
Norville IH, O'Shea K, Sarkar-Tyson M, Zheng S, Titball RW, Varani G, Harmer NJ. The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development. The Biochemical Journal. 437: 413-22. PMID 21574961 DOI: 10.1042/Bj20110345 |
0.317 |
|
| 2008 |
Goodger SJ, Robinson CJ, Murphy KJ, Gasiunas N, Harmer NJ, Blundell TL, Pye DA, Gallagher JT. Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms. The Journal of Biological Chemistry. 283: 13001-8. PMID 18281281 DOI: 10.1074/jbc.M704531200 |
0.64 |
|
| 2007 |
King JD, Harmer NJ, Preston A, Palmer CM, Rejzek M, Field RA, Blundell TL, Maskell DJ. Predicting Protein Function from Structure-The Roles of Short-chain Dehydrogenase/Reductase Enzymes in Bordetella O-antigen Biosynthesis Journal of Molecular Biology. 374: 749-763. PMID 17950751 DOI: 10.1016/J.Jmb.2007.09.055 |
0.413 |
|
| 2007 |
Harmer NJ, King JD, Palmer CM, Preston A, Maskell DJ, Blundell TL. Cloning, expression, purification and preliminary crystallographic analysis of the short-chain dehydrogenase enzymes WbmF, WbmG and WbmH from Bordetella bronchiseptica Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 63: 711-715. PMID 17671375 DOI: 10.1107/S174430910703477X |
0.392 |
|
| 2006 |
Ryu EK, Cho KJ, Kim JK, Harmer NJ, Blundell TL, Kim KH. Expression and purification of recombinant human fibroblast growth factor receptor in Escherichia coli Protein Expression and Purification. 49: 15-22. PMID 16750394 DOI: 10.1016/j.pep.2006.04.008 |
0.421 |
|
| 2006 |
Blundell TL, Sibanda BL, Montalvão RW, Brewerton S, Chelliah V, Worth CL, Harmer NJ, Davies O, Burke D. Structural biology and bioinformatics in drug design: Opportunities and challenges for target identification and lead discovery Philosophical Transactions of the Royal Society B: Biological Sciences. 361: 413-423. PMID 16524830 DOI: 10.1098/Rstb.2005.1800 |
0.687 |
|
| 2006 |
Harmer NJ, Robinson CJ, Adam LE, Ilag LL, Robinson CV, Gallagher JT, Blundell TL. Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin. The Biochemical Journal. 393: 741-8. PMID 16223363 DOI: 10.1042/BJ20050985 |
0.603 |
|
| 2005 |
Robinson CJ, Harmer NJ, Goodger SJ, Blundell TL, Gallagher JT. Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes. The Journal of Biological Chemistry. 280: 42274-82. PMID 16219767 DOI: 10.1074/jbc.M505720200 |
0.616 |
|
| 2005 |
Harmer NJ, Sivak JM, Amaya E, Blundell TL. 1.15 A crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family. Febs Letters. 579: 1161-6. PMID 15710406 DOI: 10.1016/j.febslet.2004.11.114 |
0.518 |
|
| 2004 |
Harmer NJ, Ilag LL, Mulloy B, Pellegrini L, Robinson CV, Blundell TL. Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)-FGF receptor-heparin complex Journal of Molecular Biology. 339: 821-834. PMID 15165853 DOI: 10.1016/j.jmb.2004.04.031 |
0.616 |
|
| 2004 |
Harmer NJ, Pellegrini L, Chirgadze D, Fernandez-Recio J, Blundell TL. The Crystal Structure of Fibroblast Growth Factor (FGF) 19 Reveals Novel Features of the FGF Family and Offers a Structural Basis for Its Unusual Receptor Affinity Biochemistry. 43: 629-640. PMID 14730967 DOI: 10.1021/bi035320k |
0.566 |
|
| 2003 |
Harmer NJ, Chirgadze D, Hyun Kim K, Pellegrini L, Blundell TL. The structural biology of growth factor receptor activation. Biophysical Chemistry. 100: 545-53. PMID 12646390 DOI: 10.1016/S0301-4622(02)00305-8 |
0.591 |
|
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