Year |
Citation |
Score |
2022 |
McMaster C, Bird A, Liew DF, Buchanan RR, Owen CE, Chapman WW, Pires DE. Artificial Intelligence and Deep Learning for Rheumatologists: A Primer and Review of the Literature. Arthritis & Rheumatology (Hoboken, N.J.). PMID 35857865 DOI: 10.1002/art.42296 |
0.228 |
|
2021 |
Choo D, Dushyanthen S, Gray K, Capurro D, Merolli M, Chapman BE, Pires D, Hart GK, Huckvale K, Chapman WW, Lyons K. Designing a professional development online short course to foster Learning Healthcare Systems. International Journal of Medical Informatics. 158: 104666. PMID 34971917 DOI: 10.1016/j.ijmedinf.2021.104666 |
0.188 |
|
2020 |
Pires D, Ascher DB. mycoCSM: using graph-based signatures to identify safe potent hits against Mycobacteria. Journal of Chemical Information and Modeling. PMID 32615035 DOI: 10.1021/acs.jcim.0c00362 |
0.567 |
|
2017 |
Pires DE, Ascher DB. mCSM-NA: predicting the effects of mutations on protein-nucleic acids interactions. Nucleic Acids Research. PMID 28383703 DOI: 10.1093/nar/gkx236 |
0.672 |
|
2016 |
Kano FS, Souza-Silva FA, Torres LM, Lima BA, Sousa TN, Alves JR, Rocha RS, Fontes CJ, Sanchez BA, Adams JH, Brito CF, Pires DE, Ascher DB, Sell AM, Carvalho LH. The Presence, Persistence and Functional Properties of Plasmodium vivax Duffy Binding Protein II Antibodies Are Influenced by HLA Class II Allelic Variants. Plos Neglected Tropical Diseases. 10: e0005177. PMID 27959918 DOI: 10.1371/Journal.Pntd.0005177 |
0.538 |
|
2016 |
Coelho MB, Ascher DB, Gooding C, Lang E, Maude H, Turner D, Llorian M, Pires DE, Attig J, Smith CW. Functional interactions between polypyrimidine tract binding protein and PRI peptide ligand containing proteins. Biochemical Society Transactions. 44: 1058-65. PMID 27528752 DOI: 10.1042/BST20160080 |
0.565 |
|
2016 |
Silvino AC, Costa GL, Araújo FC, Ascher DB, Pires DE, Fontes CJ, Carvalho LH, Brito CF, Sousa TN. Variation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax Relapses. Plos One. 11: e0160172. PMID 27467145 DOI: 10.1371/journal.pone.0160172 |
0.562 |
|
2016 |
Pires DE, Blundell TL, Ascher DB. mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance. Scientific Reports. 6: 29575. PMID 27384129 DOI: 10.1038/srep29575 |
0.713 |
|
2016 |
Pires DE, Ascher DB. mCSM-AB: a web server for predicting antibody-antigen affinity changes upon mutation with graph-based signatures. Nucleic Acids Research. PMID 27216816 DOI: 10.1093/nar/gkw458 |
0.604 |
|
2016 |
Pires DE, Ascher DB. CSM-lig: a web server for assessing and comparing protein-small molecule affinities. Nucleic Acids Research. PMID 27151202 DOI: 10.1093/nar/gkw390 |
0.655 |
|
2016 |
Phelan J, Coll F, McNerney R, Ascher DB, Pires DE, Furnham N, Coeck N, Hill-Cawthorne GA, Nair MB, Mallard K, Ramsay A, Campino S, Hibberd ML, Pain A, Rigouts L, et al. Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance. Bmc Medicine. 14: 31. PMID 27005572 DOI: 10.1186/S12916-016-0575-9 |
0.621 |
|
2016 |
Pires DE, Chen J, Blundell TL, Ascher DB. In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity. Scientific Reports. 6: 19848. PMID 26797105 DOI: 10.1038/srep19848 |
0.706 |
|
2015 |
Gonçalves WR, Gonçalves-Almeida VM, Arruda AL, Meira W, da Silveira CH, Pires DE, de Melo-Minardi RC. PDBest: a user-friendly platform for manipulating and enhancing protein structures. Bioinformatics (Oxford, England). 31: 2894-6. PMID 25910698 DOI: 10.1093/bioinformatics/btv223 |
0.721 |
|
2015 |
Jafri M, Wake NC, Ascher DB, Pires DE, Gentle D, Morris MR, Rattenberry E, Simpson MA, Trembath RC, Weber A, Woodward ER, Donaldson A, Blundell TL, Latif F, Maher ER. Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma. Cancer Discovery. 5: 723-9. PMID 25873077 DOI: 10.1158/2159-8290.CD-14-1096 |
0.639 |
|
2015 |
Pires DE, Blundell TL, Ascher DB. pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures. Journal of Medicinal Chemistry. 58: 4066-72. PMID 25860834 DOI: 10.1021/acs.jmedchem.5b00104 |
0.64 |
|
2015 |
Nemethova M, Radvanszky J, Kadasi L, Ascher DB, Pires DE, Blundell TL, Porfirio B, Mannoni A, Santucci A, Milucci L, Sestini S, Biolcati G, Sorge F, Aurizi C, Aquaron R, et al. Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on 'black bone disease' in Italy. European Journal of Human Genetics : Ejhg. PMID 25804398 DOI: 10.1038/Ejhg.2015.60 |
0.599 |
|
2015 |
Usher JL, Ascher DB, Pires DE, Milan AM, Blundell TL, Ranganath LR. Analysis of HGD Gene Mutations in Patients with Alkaptonuria from the United Kingdom: Identification of Novel Mutations. Jimd Reports. PMID 25681086 DOI: 10.1007/8904_2014_380 |
0.667 |
|
2015 |
Pires DE, Blundell TL, Ascher DB. Platinum: a database of experimentally measured effects of mutations on structurally defined protein-ligand complexes. Nucleic Acids Research. 43: D387-91. PMID 25324307 DOI: 10.1093/nar/gku966 |
0.694 |
|
2014 |
Gossage L, Pires DE, Olivera-Nappa Á, Asenjo J, Bycroft M, Blundell TL, Eisen T. An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma. Human Molecular Genetics. 23: 5976-88. PMID 24969085 DOI: 10.1093/Hmg/Ddu321 |
0.571 |
|
2014 |
Pires DE, Ascher DB, Blundell TL. DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach. Nucleic Acids Research. 42: W314-9. PMID 24829462 DOI: 10.1093/nar/gku411 |
0.699 |
|
2014 |
Pires DE, Ascher DB, Blundell TL. mCSM: predicting the effects of mutations in proteins using graph-based signatures. Bioinformatics (Oxford, England). 30: 335-42. PMID 24281696 DOI: 10.1093/bioinformatics/btt691 |
0.716 |
|
2013 |
Pires DE, de Melo-Minardi RC, da Silveira CH, Campos FF, Meira W. aCSM: noise-free graph-based signatures to large-scale receptor-based ligand prediction. Bioinformatics (Oxford, England). 29: 855-61. PMID 23396119 DOI: 10.1093/bioinformatics/btt058 |
0.71 |
|
2011 |
Pires DE, de Melo-Minardi RC, dos Santos MA, da Silveira CH, Santoro MM, Meira W. Cutoff Scanning Matrix (CSM): structural classification and function prediction by protein inter-residue distance patterns. Bmc Genomics. 12: S12. PMID 22369665 DOI: 10.1186/1471-2164-12-S4-S12 |
0.739 |
|
2009 |
da Silveira CH, Pires DE, Minardi RC, Ribeiro C, Veloso CJ, Lopes JC, Meira W, Neshich G, Ramos CH, Habesch R, Santoro MM. Protein cutoff scanning: A comparative analysis of cutoff dependent and cutoff free methods for prospecting contacts in proteins. Proteins. 74: 727-43. PMID 18704933 DOI: 10.1002/Prot.22187 |
0.714 |
|
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