Year |
Citation |
Score |
2023 |
Zhao F, Hang K, Zhou Q, Shao L, Li H, Li W, Lin S, Dai A, Cai X, Liu Y, Xu Y, Feng W, Yang D, Wang MW. Molecular basis of signal transduction mediated by the human GIPR splice variants. Proceedings of the National Academy of Sciences of the United States of America. 120: e2306145120. PMID 37792509 DOI: 10.1073/pnas.2306145120 |
0.315 |
|
2023 |
Zhou Q, Liu X, Neri D, Li W, Favalli N, Bassi G, Yang S, Yang D, Vogt PK, Wang MW. Structural insights into the interaction of three Y-shaped ligands with PI3Kα. Proceedings of the National Academy of Sciences of the United States of America. 120: e2304071120. PMID 37585458 DOI: 10.1073/pnas.2304071120 |
0.346 |
|
2022 |
Zhao W, Han S, Qiu N, Feng W, Lu M, Zhang W, Wang M, Zhou Q, Chen S, Xu W, Du J, Chu X, Yi C, Dai A, Hu L, et al. Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Research. PMID 35739238 DOI: 10.1038/s41422-022-00679-x |
0.318 |
|
2021 |
Lin G, Feng Y, Cai X, Zhou C, Shao L, Chen Y, Chen L, Liu Q, Zhou Q, Bathgate RAD, Yang D, Wang MW. High-Throughput Screening Campaign Identified a Potential Small Molecule RXFP3/4 Agonist. Molecules (Basel, Switzerland). 26. PMID 34946593 DOI: 10.3390/molecules26247511 |
0.301 |
|
2021 |
Wang X, Cheng X, Zhao L, Wang Y, Ye C, Zou X, Dai A, Cong Z, Chen J, Zhou Q, Xia T, Jiang H, Xu HE, Yang D, Wang MW. Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34353904 DOI: 10.1073/pnas.2101279118 |
0.326 |
|
2021 |
Zhou Q, Guo W, Dai A, Cai X, Vass M, de Graaf C, Shui W, Zhao S, Yang D, Wang MW. Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening. Biomolecules. 11. PMID 34201418 DOI: 10.3390/biom11070929 |
0.382 |
|
2021 |
Cong Z, Chen LN, Ma H, Zhou Q, Zou X, Ye C, Dai A, Liu Q, Huang W, Sun X, Wang X, Xu P, Zhao L, Xia T, Zhong W, et al. Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nature Communications. 12: 3763. PMID 34145245 DOI: 10.1038/s41467-021-24058-z |
0.345 |
|
2021 |
Lu Y, Liu H, Yang D, Zhong L, Xin Y, Zhao S, Wang MW, Zhou Q, Shui W. Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A Receptor Targeting the Sodium Ion Pocket. Acs Chemical Biology. PMID 34048655 DOI: 10.1021/acschembio.0c00899 |
0.386 |
|
2020 |
Lin G, Liu Q, Dai A, Cai X, Zhou Q, Wang X, Chen Y, Ye C, Li J, Yang D, Wang MW. Characterization of a naturally occurring mutation V368M in the human glucagon receptor and its association with metabolic disorders. The Biochemical Journal. 477: 2581-2594. PMID 32677665 DOI: 10.1042/Bcj20200235 |
0.306 |
|
2020 |
Wang YZ, Liu X, Way G, Madarha V, Zhou QT, Yang DH, Liao JY, Wang MW. An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9. Acta Pharmacologica Sinica. PMID 32341466 DOI: 10.1038/S41401-020-0405-7 |
0.32 |
|
2020 |
Tan L, Zhou Q, Yan W, Sun J, Kozikowski AP, Zhao S, Huang XP, Cheng J. Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands. Journal of Medicinal Chemistry. PMID 32282200 DOI: 10.1021/Acs.Jmedchem.9B01835 |
0.4 |
|
2019 |
Zhou Q, Yang D, Wu M, Guo Y, Guo W, Zhong L, Cai X, Dai A, Jang W, Shakhnovich EI, Liu ZJ, Stevens RC, Lambert NA, Babu MM, Wang MW, et al. Common activation mechanism of class A GPCRs. Elife. 8. PMID 31855179 DOI: 10.7554/Elife.50279 |
0.561 |
|
2019 |
Chen X, Xu Y, Qu L, Wu L, Han GW, Guo Y, Wu Y, Zhou Q, Sun Q, Chu C, Yang J, Yang L, Wang Q, Yuan S, Wang L, et al. Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α Adrenergic Receptor. Cell Reports. 29: 2936-2943.e4. PMID 31801061 DOI: 10.1016/J.Celrep.2019.10.112 |
0.334 |
|
2019 |
Qu L, Zhou Q, Xu Y, Guo Y, Chen X, Yao D, Han GW, Liu ZJ, Stevens RC, Zhong G, Wu D, Zhao S. Structural Basis of the Diversity of Adrenergic Receptors. Cell Reports. 29: 2929-2935.e4. PMID 31801060 DOI: 10.1016/J.Celrep.2019.10.088 |
0.422 |
|
2019 |
Wu Y, Tong J, Ding K, Zhou Q, Zhao S. GPCR Allosteric Modulator Discovery. Advances in Experimental Medicine and Biology. 1163: 225-251. PMID 31707706 DOI: 10.1007/978-981-13-8719-7_10 |
0.401 |
|
2019 |
Zhou Q, Yang D, Wu M, Guo Y, Guo W, Zhong L, Cai X, Dai A, Jang W, Shakhnovich EI, Liu Z, Stevens RC, Lambert NA, Babu MM, Wang M, et al. Author response: Common activation mechanism of class A GPCRs Elife. DOI: 10.7554/Elife.50279.Sa2 |
0.442 |
|
2018 |
Qin S, Meng M, Yang D, Bai W, Lu Y, Peng Y, Song G, Wu Y, Zhou Q, Zhao S, Huang X, McCorvy JD, Cai X, Dai A, Roth BL, et al. High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening. Chemical Science. 9: 3192-3199. PMID 29732102 DOI: 10.1039/C7Sc04698G |
0.441 |
|
2018 |
Qiu B, Xia B, Zhou Q, Lu Y, He M, Hasegawa K, Ma Z, Zhang F, Gu L, Mao Q, Wang F, Zhao S, Gao Z, Liao J. Succinate-acetate permease from Citrobacter koseri is an anion channel that unidirectionally translocates acetate. Cell Research. 28: 644-654. DOI: 10.2210/Pdb5Ys8/Pdb |
0.312 |
|
2017 |
Ma Y, Yue Y, Ma Y, Zhang Q, Zhou Q, Song Y, Shen Y, Li X, Ma X, Li C, Hanson MA, Han GW, Sickmier EA, Swaminath G, Zhao S, et al. Structural Basis for Apelin Control of the Human Apelin Receptor. Structure (London, England : 1993). PMID 28528775 DOI: 10.1016/J.Str.2017.04.008 |
0.428 |
|
2017 |
Song G, Yang D, Wang Y, de Graaf C, Zhou Q, Jiang S, Liu K, Cai X, Dai A, Lin G, Liu D, Wu F, Wu Y, Zhao S, Ye L, et al. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature. PMID 28514449 DOI: 10.1038/Nature22378 |
0.376 |
|
2017 |
Zhou Q, Sun X, Xia X, Fan Z, Luo Z, Zhao S, Shakhnovich EI, Liang H. Exploring the Mutational Robustness of Nucleic Acids by Searching Genotype Neighbourhoods in Sequence Space. The Journal of Physical Chemistry Letters. PMID 28045264 DOI: 10.1021/Acs.Jpclett.6B02769 |
0.58 |
|
2016 |
Zhou Q, Liang H, Shakhnovich E. Virtual Screening of Human O-GlcNAc Transferase Inhibitors Chinese Journal of Chemical Physics. 29: 374-380. DOI: 10.1063/1674-0068/29/Cjcp1510211 |
0.562 |
|
2015 |
Zhou Q, Xia X, Luo Z, Liang H, Shakhnovich E. Searching the Sequence Space for Potent Aptamers Using SELEX in Silico. Journal of Chemical Theory and Computation. 11: 5939-46. PMID 26642994 DOI: 10.1021/Acs.Jctc.5B00707 |
0.596 |
|
2014 |
Li S, Chen D, Zhou Q, Wang W, Gao L, Jiang J, Liang H, Liu Y, Liang G, Cui H. A general chemiluminescence strategy for measuring aptamer-target binding and target concentration. Analytical Chemistry. 86: 5559-66. PMID 24828232 DOI: 10.1021/Ac501061C |
0.56 |
|
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