Zhihong Guo, Ph.D. - Publications

Affiliations: 
2000- Chemistry Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 
Area:
Bioorganic chemistry and chemical biology
Website:
http://www-chem.ust.hk/Faculty%20staff/Guo/content.htm

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Sun Q, Heater BS, Li TL, Ye W, Guo Z, Chan MK. Cry3Aa*SpyCatcher Fusion Crystals Produced in Bacteria as Scaffolds for Multienzyme Coimmobilization. Bioconjugate Chemistry. PMID 35100510 DOI: 10.1021/acs.bioconjchem.2c00003  0.379
2020 Jiang Y, Qin M, Guo Z. Substrate recognition and catalytic mechanism of the phosphate acyltransferase PlsX from Bacillus subtilis. Chembiochem : a European Journal of Chemical Biology. PMID 32180316 DOI: 10.1002/Cbic.202000015  0.522
2018 Qin M, Song H, Dai X, Chen Y, Guo Z. Two active site arginines are critical determinants of substrate binding and catalysis in MenD, a thiamine-dependent enzyme in menaquinone biosynthesis. The Biochemical Journal. PMID 30341164 DOI: 10.1042/Bcj20180548  0.806
2018 Guo Z, Qin M, Song H, Dai X, Chan CK, Chan W. Single turnover kinetics reveal a distinct mode of thiamine diphosphate-dependent catalysis in vitamin K biosynthesis. Chembiochem : a European Journal of Chemical Biology. PMID 29726079 DOI: 10.1002/Cbic.201800143  0.769
2017 Chen Y, Li TL, Lin X, Li X, Li XD, Guo Z. Crystal structure of the thioesterification conformation of Bacillus subtilis o-succinylbenzoyl-CoA synthetase reveals a distinct substrate binding mode. The Journal of Biological Chemistry. PMID 28559280 DOI: 10.1074/Jbc.M117.790410  0.792
2016 Shi J, Cao X, Chen Y, Cronan JE, Guo Z. An Atypical α/β-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus influenzae. Biochemistry. 55: 6705-6717. PMID 27933801 DOI: 10.1021/Acs.Biochem.6B00818  0.76
2016 Chen Y, Jiang Y, Guo Z. Mechanistic Insights from the Crystal Structure of Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase Complexed with the Adenylate Intermediate. Biochemistry. 55: 6685-6695. PMID 27933791 DOI: 10.1021/Acs.Biochem.6B00889  0.78
2016 Song H, Dong C, Qin M, Chen Y, Sun Y, Liu J, Chan W, Guo Z. A thiamine-dependent enzyme utilizes an active tetrahedral intermediate in vitamin K biosynthesis. Journal of the American Chemical Society. PMID 27213829 DOI: 10.1021/Jacs.6B03437  0.795
2016 Song JX, Sun YR, Peluso I, Zeng Y, Yu X, Lu JH, Xu Z, Wang MZ, Liu LF, Huang YY, Chen LL, Durairajan SS, Zhang HJ, Zhou B, Zhang HQ, ... ... Guo Z, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 0. PMID 27172265 DOI: 10.1080/15548627.2016.1179404  0.323
2015 Chen Y, Sun Y, Song H, Guo Z. Structural Basis for the ATP-dependent Configuration of Adenylation Active Site in Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase. The Journal of Biological Chemistry. 290: 23971-83. PMID 26276389 DOI: 10.1074/Jbc.M115.676304  0.805
2015 Jiang L, Zeng Y, Sun Q, Sun Y, Guo Z, Qu JY, Yao S. Microsecond protein folding events revealed by time-resolved fluorescence resonance energy transfer in a microfluidic mixer. Analytical Chemistry. 87: 5589-95. PMID 25938953 DOI: 10.1021/Acs.Analchem.5B00366  0.455
2015 Song H, Xu R, Guo Z. Identification and characterization of a methionine γ-lyase in the calicheamicin biosynthetic cluster of Micromonospora echinospora. Chembiochem : a European Journal of Chemical Biology. 16: 100-9. PMID 25404066 DOI: 10.1002/Cbic.201402489  0.777
2015 Chen Y, Sun Y, Song H, Guo Z. Structural basis for the atp-dependent configuration of adenylation active site in bacillus subtilis o-succinylbenzoyl-coa synthetase Journal of Biological Chemistry. 290: 23971-23983. DOI: 10.1074/jbc.M115.676304  0.768
2015 Song H, Xu R, Guo Z. Inside Cover: Identification and Characterization of a Methionine γ‐Lyase in the Calicheamicin Biosynthetic Cluster of Micromonospora echinospora (ChemBioChem 1/2015) Chembiochem. 16: 2-2. DOI: 10.1002/Cbic.201490068  0.666
2014 Song H, Sung HP, Tse YS, Jiang M, Guo Z. Ligand-dependent active-site closure revealed in the crystal structure of Mycobacterium tuberculosis MenB complexed with product analogues. Acta Crystallographica. Section D, Biological Crystallography. 70: 2959-69. PMID 25372686 DOI: 10.1107/S1399004714019440  0.785
2014 Kang W, Liu J, Wang J, Nie Y, Guo Z, Xia J. Cascade biocatalysis by multienzyme-nanoparticle assemblies. Bioconjugate Chemistry. 25: 1387-94. PMID 25020147 DOI: 10.1021/Bc5002399  0.422
2014 Sun Y, Yin S, Feng Y, Li J, Zhou J, Liu C, Zhu G, Guo Z. Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad. The Journal of Biological Chemistry. 289: 15867-79. PMID 24737327 DOI: 10.1074/Jbc.M113.535641  0.512
2013 Sun Y, Song H, Li J, Li Y, Jiang M, Zhou J, Guo Z. Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily. Plos One. 8: e63095. PMID 23658663 DOI: 10.1371/Journal.Pone.0063095  0.785
2013 Johnston JM, Jiang M, Guo Z, Baker EN. Crystal structures of E. coli native MenH and two active site mutants. Plos One. 8: e61325. PMID 23637813 DOI: 10.1371/Journal.Pone.0061325  0.536
2013 Chen M, Ma X, Chen X, Jiang M, Song H, Guo Z. Identification of a hotdog fold thioesterase involved in the biosynthesis of menaquinone in Escherichia coli. Journal of Bacteriology. 195: 2768-75. PMID 23564174 DOI: 10.1128/Jb.00141-13  0.765
2013 Chen M, Jiang M, Guo Z. The thiamine-dependent enzyme of the vitamin K biosynthesis catalyzes reductive C-N bond ligation between nitroarenes and α-ketoacids Science China-Chemistry. 56: 312-320. DOI: 10.1007/S11426-012-4792-6  0.47
2012 Sun Y, Song H, Li J, Jiang M, Li Y, Zhou J, Guo Z. Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways. Biochemistry. 51: 4580-9. PMID 22606952 DOI: 10.1021/Bi300486J  0.79
2012 Song H, Guo Z. Characterization of 1,4-dihydroxy-2-naphthoyl-coenzyme A synthase (MenB) in phylloquinone biosynthesis of Synechocystis sp. PCC 6803 Science China-Chemistry. 55: 98-105. DOI: 10.1007/S11426-011-4448-Y  0.769
2011 Chen M, Jiang M, Sun Y, Guo ZF, Guo Z. Stabilization of the second oxyanion intermediate by 1,4-dihydroxy-2-naphthoyl-coenzyme A synthase of the menaquinone pathway: spectroscopic evidence of the involvement of a conserved aspartic acid. Biochemistry. 50: 5893-904. PMID 21627110 DOI: 10.1021/Bi200376X  0.544
2011 Haynes RK, Cheu KW, Tang MM, Chen MJ, Guo ZF, Guo ZH, Coghi P, Monti D. Reactions of antimalarial peroxides with each of leucomethylene blue and dihydroflavins: flavin reductase and the cofactor model exemplified. Chemmedchem. 6: 279-91. PMID 21275052 DOI: 10.1002/Cmdc.201000508  0.354
2010 Johnston JM, Jiang M, Guo Z, Baker EN. Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis. Acta Crystallographica. Section D, Biological Crystallography. 66: 909-17. PMID 20693690 DOI: 10.1107/S0907444910025771  0.42
2010 Jiang M, Chen M, Guo ZF, Guo Z. A bicarbonate cofactor modulates 1,4-dihydroxy-2-naphthoyl-coenzyme a synthase in menaquinone biosynthesis of Escherichia coli. The Journal of Biological Chemistry. 285: 30159-69. PMID 20643650 DOI: 10.1074/Jbc.M110.147702  0.571
2010 Guo ZF, Jiang M, Zheng S, Guo Z. Structural change of the enterobactin synthetase in crowded solution and its relation to crowding-enhanced product specificity in nonribosomal enterobactin biosynthesis. Bioorganic & Medicinal Chemistry Letters. 20: 3855-8. PMID 20627563 DOI: 10.1016/J.Bmcl.2010.05.051  0.347
2010 Dawson A, Chen M, Fyfe PK, Guo Z, Hunter WN. Structure and reactivity of Bacillus subtilis MenD catalyzing the first committed step in menaquinone biosynthesis. Journal of Molecular Biology. 401: 253-64. PMID 20600129 DOI: 10.1016/J.Jmb.2010.06.025  0.527
2009 Jiang M, Chen X, Wu XH, Chen M, Wu YD, Guo Z. Catalytic mechanism of SHCHC synthase in the menaquinone biosynthesis of Escherichia coli: identification and mutational analysis of the active site residues. Biochemistry. 48: 6921-31. PMID 19545176 DOI: 10.1021/Bi900897H  0.499
2009 Zheng Y, Guo Z, Cai Z. Combination of beta-elimination and liquid chromatography/quadrupole time-of-flight mass spectrometry for the determination of O-glycosylation sites. Talanta. 78: 358-63. PMID 19203595 DOI: 10.1016/J.Talanta.2008.11.026  0.308
2009 Guo ZF, Sun Y, Zheng S, Guo Z. Preferential hydrolysis of aberrant intermediates by the type II thioesterase in Escherichia coli nonribosomal enterobactin synthesis: substrate specificities and mutagenic studies on the active-site residues. Biochemistry. 48: 1712-22. PMID 19193103 DOI: 10.1021/Bi802165X  0.502
2008 Jiang M, Chen X, Guo ZF, Cao Y, Chen M, Guo Z. Identification and characterization of (1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase in the menaquinone biosynthesis of Escherichia coli. Biochemistry. 47: 3426-34. PMID 18284213 DOI: 10.1021/Bi7023755  0.501
2008 Guo ZF, Jiang M, Zheng S, Guo Z. Suppression of linear side products by macromolecular crowding in nonribosomal enterobactin biosynthesis. Organic Letters. 10: 649-52. PMID 18211078 DOI: 10.1021/Ol7030153  0.368
2007 Ding Y, Qin C, Guo Z, Niu W, Zhang R, Li Y. Solid-phase total synthesis and antimicrobial activities of loloatins A-D. Chemistry & Biodiversity. 4: 2827-34. PMID 18081093 DOI: 10.1002/Cbdv.200790232  0.302
2007 Jiang M, Chen M, Cao Y, Yang Y, Sze KH, Chen X, Guo Z. Determination of the stereochemistry of 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate, a key intermediate in menaquinone biosynthesis. Organic Letters. 9: 4765-7. PMID 17956107 DOI: 10.1021/Ol702126M  0.34
2007 Jiang M, Cao Y, Guo ZF, Chen M, Chen X, Guo Z. Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity. Biochemistry. 46: 10979-89. PMID 17760421 DOI: 10.1021/Bi700810X  0.505
2007 Jiang M, Guo Z. Effects of macromolecular crowding on the intrinsic catalytic efficiency and structure of enterobactin-specific isochorismate synthase. Journal of the American Chemical Society. 129: 730-1. PMID 17243787 DOI: 10.1021/Ja065064+  0.435
2007 Yang Z, Ho PL, Liang G, Chow KH, Wang Q, Cao Y, Guo Z, Xu B. Using beta-lactamase to trigger supramolecular hydrogelation. Journal of the American Chemical Society. 129: 266-7. PMID 17212393 DOI: 10.1021/Ja0675604  0.347
2005 Cao S, Yang Y, Ng NL, Guo Z. Macrolactonization catalyzed by the terminal thioesterase domain of the nonribosomal peptide synthetase responsible for lichenysin biosynthesis. Bioorganic & Medicinal Chemistry Letters. 15: 2595-9. PMID 15863324 DOI: 10.1016/J.Bmcl.2005.03.035  0.427
2004 Bu X, Wu X, Ng NL, Mak CK, Qin C, Guo Z. Synthesis of gramicidin S and its analogues via an on-resin macrolactamization assisted by a predisposed conformation of the linear precursors. The Journal of Organic Chemistry. 69: 2681-5. PMID 15074913 DOI: 10.1021/Jo035712X  0.322
2004 Qin C, Zhong X, Ng NL, Bu X, Chan WS, Guo Z. Facile solid-phase synthesis of cyclic decapeptide antibiotic streptocidins A-D Tetrahedron Letters. 45: 217-220. DOI: 10.1016/J.Tetlet.2003.10.134  0.307
2003 Qin C, Zhong X, Bu X, Ng NL, Guo Z. Dissociation of antibacterial and hemolytic activities of an amphipathic peptide antibiotic. Journal of Medicinal Chemistry. 46: 4830-3. PMID 14584933 DOI: 10.1021/Jm0341352  0.355
2003 Wu X, Bu X, Wong KM, Yan W, Guo Z. Biomimetic synthesis of gramicidin s and analogues by enzymatic cyclization of linear precursors on solid support. Organic Letters. 5: 1749-52. PMID 12735768 DOI: 10.1021/Ol034437Y  0.312
2003 Beyer N, Alam J, Hallis TM, Guo Z, Liu HW. The biosynthesis of GDP-L-colitose: C-3 deoxygenation is catalyzed by a unique coenzyme B6-dependent enzyme. Journal of the American Chemical Society. 125: 5584-5. PMID 12733868 DOI: 10.1021/Ja030088R  0.447
2002 Bu X, Wu X, Xie G, Guo Z. Synthesis of tyrocidine A and its analogues by spontaneous cyclization in aqueous solution. Organic Letters. 4: 2893-5. PMID 12182582 DOI: 10.1021/Ol0263191  0.307
2002 Xie G, Uttamchandani M, Chen GY, Bu X, Lin SS, Wong KM, Yan W, Yao SQ, Guo Z. Substrate spectrum of tyrocidine thioesterase probed with randomized peptide N-acetylcysteamine thioesters. Bioorganic & Medicinal Chemistry Letters. 12: 989-92. PMID 11959010 DOI: 10.1016/S0960-894X(02)00067-7  0.525
2001 Chen H, Zhao Z, Hallis TM, Guo Z, Liu HW. Insights into the Branched-Chain Formation of Mycarose: Methylation Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase. Angewandte Chemie (International Ed. in English). 40: 607-610. PMID 29712024 DOI: 10.1002/1521-3773(20010202)40:3<607::Aid-Anie607>3.0.Co;2-8  0.323
2000 Guo Z, Zhou D, Schultz PG. Designing small-molecule switches for protein-protein interactions. Science (New York, N.Y.). 288: 2042-5. PMID 10856217 DOI: 10.1126/Science.288.5473.2042  0.46
1999 Chen H, Agnihotri G, Guo Z, Que NLS, Chen XH, Liu H. Biosynthesis of Mycarose:  Isolation and Characterization of Enzymes Involved in the C-2 Deoxygenation Journal of the American Chemical Society. 121: 8124-8125. DOI: 10.1021/Ja991713O  0.409
1996 Li D, Guo Z, Liu H. Mechanistic studies of the inactivation of crotonase by (methylenecyclopropyl)formyl-CoA Journal of the American Chemical Society. 118: 275-276. DOI: 10.1021/Ja952621B  0.408
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