Youla Tsantrizos, Ph.D.

1997- Chemistry McGill University, Montreal, QC, Canada 
"Youla Tsantrizos"

2012 - Queen Elizabeth II Diamond Jubilee Medal "for services to Canada"

Cross-listing: Chemistry Tree


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George Just grad student 1977-1979 McGill (Chemistry Tree)
Kelvin K. Ogilvie grad student 1987-1990 McGill (Chemistry Tree)
David E. Cane post-doc 1990-1991 Brown (Chemistry Tree)


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Xian-Shu Yang grad student 2000 McGill (Chemistry Tree)
Lee D. Fader grad student 2002 McGill (Chemistry Tree)
J. De Schutter grad student 2013 McGill (Chemistry Tree)
Yih-Shyan Lin grad student 2014 McGill (Chemistry Tree)
Warren Chew post-doc 1996 McGill (Chemistry Tree)
John Mancuso post-doc 2009-2010 McGill (Chemistry Tree)
Olivier Leogane post-doc 2011-2012 McGill (Chemistry Tree)
BETA: Related publications


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Lee HF, Lacbay CM, Boutin R, et al. (2022) Synthesis and Evaluation of Structurally Diverse C-2-Substituted Thienopyrimidine-Based Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase. Journal of Medicinal Chemistry
Park J, Rodionov D, De Schutter JW, et al. (2017) Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase. Plos One. 12: e0186447
Fader LD, Bailey M, Beaulieu E, et al. (2016) Aligning Potency and Pharmacokinetic Properties for Pyridine-Based NCINIs. Acs Medicinal Chemistry Letters. 7: 797-801
Jansen G, Golizeh M, Martel-Lorion C, et al. (2016) A covalent cysteine-targeting kinase inhibitor of Ire1 permits allosteric control of endoribonuclease activity. Chembiochem : a European Journal of Chemical Biology
Fandrick KR, Li W, Zhang Y, et al. (2015) Concise and Practical Asymmetric Synthesis of a Challenging Atropisomeric HIV Integrase Inhibitor. Angewandte Chemie (International Ed. in English). 54: 7144-8
Gritzalis D, Park J, Chiu W, et al. (2015) Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. Bioorganic & Medicinal Chemistry Letters. 25: 1117-23
Lacbay CM, Mancuso J, Lin YS, et al. (2014) Modular assembly of purine-like bisphosphonates as inhibitors of HIV-1 reverse transcriptase. Journal of Medicinal Chemistry. 57: 7435-49
Fader LD, Carson R, Morin S, et al. (2014) Minimizing the Contribution of Enterohepatic Recirculation to Clearance in Rat for the NCINI Class of Inhibitors of HIV. Acs Medicinal Chemistry Letters. 5: 711-6
De Schutter JW, Park J, Leung CY, et al. (2014) Multistage screening reveals chameleon ligands of the human farnesyl pyrophosphate synthase: implications to drug discovery for neurodegenerative diseases. Journal of Medicinal Chemistry. 57: 5764-76
Fader LD, Malenfant E, Parisien M, et al. (2014) Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1. Acs Medicinal Chemistry Letters. 5: 422-7
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