Benoît Sanson

Affiliations: 
Université Joseph Fourier (Grenoble) 
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"Benoît Sanson"

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Martin Weik grad student 2009 Université Joseph Fourier (Grenoble)
 (Dynamique structurale de l'acétylcholinestérase étudiée par cristallographie aux rayons X et par une méthode spectroscopique complémentaire)
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Kliachyna M, Santoni G, Nussbaum V, et al. (2014) Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- Aldoxime and -Amidoxime hybrids as efficient uncharged reactivators of nerve agent-Inhibited human acetylcholinesterase European Journal of Medicinal Chemistry. 78: 455-467
Sanson B, Colletier JP, Xu Y, et al. (2011) Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations Protein Science. 20: 1114-1118
Sanson B, Nachon F, Colletier JP, et al. (2009) Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime Journal of Medicinal Chemistry. 52: 7593-7603
Hansmann T, Sanson B, Stojan J, et al. (2009) Kinetic insight into the mechanism of cholinesterasterase inhibition by aflatoxin B1 to develop biosensors. Biosensors & Bioelectronics. 24: 2119-24
Colletier JP, Bourgeois D, Sanson B, et al. (2008) Shoot-and-trap: Use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallography Proceedings of the National Academy of Sciences of the United States of America. 105: 11742-11747
Colletier JP, Royant A, Specht A, et al. (2007) Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography. Acta Crystallographica. Section D, Biological Crystallography. 63: 1115-28
Sanson B, Nachon F, Colletier J, et al. (2007) Crystal structures of conjugates of soman withTcAChE Acta Crystallographica Section a Foundations of Crystallography. 63: s122-s123
Colletier JP, Sanson B, Nachon F, et al. (2006) Conformational flexibility in the peripheral site of Torpedo californica acetylcholinesterase revealed by the complex structure with a bifunctional inhibitor. Journal of the American Chemical Society. 128: 4526-7
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