Joseph E. Wedekind, Ph. D.

Affiliations: 
Biochemistry University of Rochester, Rochester, NY 
Area:
x-ray crystallography, ncRNA structure, APOBEC3G
Website:
http://www.urmc.rochester.edu/people/23504899-joseph-e-wedekind
Google:
"Joseph Wedekind"
Cross-listing: Chemistry Tree

Parents

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Ivan Rayment grad student 1995 UW Madison (Chemistry Tree)
David Bruce McKay post-doc 1995-1999 Stanford University Medical Center (Chemistry Tree)

Children

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Kefang Xie grad student 2005 Rochester (Chemistry Tree)
Franz Gruswitz grad student 2006 Rochester (Chemistry Tree)
Celeste MacElrevey grad student 2002-2007 University of Rochester Medical Center (Chemistry Tree)
Geoffrey M. Lippa grad student 2007-2013 University of Rochester Medical Center
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Publications

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Srivastava Y, Bonn-Breach R, Chavali SS, et al. (2021) Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing. Crystals. 11
Warnasooriya C, Ling C, Belashov IA, et al. (2018) Observation of preQ-II riboswitch dynamics using single-molecule FRET. Rna Biology
Belashov IA, Crawford DW, Cavender CE, et al. (2018) Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription. Nucleic Acids Research
Dutta D, Belashov IA, Wedekind JE. (2018) Coupling GFP Expression with Chemical Modification to Probe Functionally Relevant Riboswitch Conformations in Live Bacteria. Biochemistry
Wedekind JE, Dutta D, Belashov IA, et al. (2017) Metalloriboswitches: RNA-Based Inorganic Ion Sensors that Regulate Genes. The Journal of Biological Chemistry
Aytenfisu AH, Liberman JA, Wedekind JE, et al. (2015) Molecular mechanism for preQ1-II riboswitch function revealed by molecular dynamics. Rna (New York, N.Y.). 21: 1898-907
Dutta D, Wedekind JE. (2015) Gene Regulation Gets in Tune: How Riboswitch Tertiary-Structure Networks Adapt to Meet the Needs of Their Transcription Units. Journal of Molecular Biology
Liberman JA, Suddala KC, Aytenfisu A, et al. (2015) Structural analysis of a class III preQ1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics. Proceedings of the National Academy of Sciences of the United States of America
Liberman JA, Bogue JT, Jenkins JL, et al. (2014) ITC analysis of ligand binding to preQ₁ riboswitches. Methods in Enzymology. 549: 435-50
Heldenbrand H, Janowski PA, Giamba?u G, et al. (2014) Evidence for the role of active site residues in the hairpin ribozyme from molecular simulations along the reaction path. Journal of the American Chemical Society. 136: 7789-92
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