Bogdana Goryanova

2008-2015 Chemistry State University of New York, Buffalo, Buffalo, NY, United States 
"Bogdana Goryanova"
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Goryanova B, Amyes TL, Richard JP. (2019) Role of the Carboxylate in Enzyme-Catalyzed Decarboxylation of Orotidine 5'-Monophosphate: Transition State Stabilization Dominates Over Ground State Destabilization. Journal of the American Chemical Society
Goryanova B, Goldman LM, Ming S, et al. (2015) Rate and Equilibrium Constants for an Enzyme Conformational Change during Catalysis by Orotidine 5'-Monophosphate Decarboxylase. Biochemistry. 54: 4555-64
Goldman LM, Amyes TL, Goryanova B, et al. (2014) Enzyme architecture: Deconstruction of the enzyme-activating phosphodianion interactions of orotidine 5′-monophosphate decarboxylase Journal of the American Chemical Society. 136: 10156-10165
Richard JP, Amyes TL, Goryanova B, et al. (2014) Enzyme architecture: on the importance of being in a protein cage. Current Opinion in Chemical Biology. 21: 1-10
Goryanova B, Goldman LM, Amyes TL, et al. (2013) Role of a guanidinium cation-phosphodianion pair in stabilizing the vinyl carbanion intermediate of orotidine 5′-phosphate decarboxylase-catalyzed reactions Biochemistry. 52: 7500-7511
Goryanova B, Spong K, Amyes TL, et al. (2013) Catalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates. Biochemistry. 52: 537-46
Desai BJ, Wood BM, Fedorov AA, et al. (2012) Conformational changes in orotidine 5′-monophosphate decarboxylase: A structure-based explanation for how the 5′-phosphate group activates the enzyme Biochemistry. 51: 8665-8678
Goryanova B, Amyes TL, Gerlt JA, et al. (2011) OMP decarboxylase: Phosphodianion binding energy is used to stabilize a vinyl carbanion intermediate Journal of the American Chemical Society. 133: 6545-6548
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