Mark Hulett

Department of Biochemistry and Genetics La Trobe University, Flora Hill, Victoria, Australia 
"Mark Hulett"
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Hein MJA, Kvansakul M, Lay FT, et al. (2022) Defensin-lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics. Biochemical Society Transactions
Lay FT, Ryan GF, Caria S, et al. (2019) Structural and functional characterization of the membrane-permeabilizing activity of Nicotiana occidentalis defensin NoD173 and protein engineering to enhance oncolysis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802540R
Järvå M, Phan TK, Lay FT, et al. (2018) Human β-defensin 2 kills through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization. Science Advances. 4: eaat0979
Järvå M, Lay FT, Phan TK, et al. (2018) X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex. Nature Communications. 9: 1962
Anasir MI, Baxter AA, Poon IKH, et al. (2017) Structural and Functional Insight into Canarypox Virus CNP058 Mediated Regulation of Apoptosis. Viruses. 9
Baxter AA, Lay FT, Poon IKH, et al. (2017) Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects. Cellular and Molecular Life Sciences : Cmls
Järvå M, Lay FT, Hulett MD, et al. (2017) Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type. Febs Letters
Priebatsch KM, Kvansakul M, Poon IK, et al. (2017) Functional Regulation of the Plasma Protein Histidine-Rich Glycoprotein by Zn(2+) in Settings of Tissue Injury. Biomolecules. 7
Priebatsch KM, Poon IK, Patel KK, et al. (2016) Divalent metal binding by histidine-rich glycoprotein (HRG) differentially regulates higher order oligomerisation and proteolytic processing. Febs Letters
Kvansakul M, Lay FT, Adda CG, et al. (2016) Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization. Proceedings of the National Academy of Sciences of the United States of America
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