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Matthew A. Desieno, Ph.D. - Publications

Affiliations: 
Chemical & Biomolecular Engr University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Directed evolution, metabolic engineering, natural product, gene therapy, synthetic biology
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nguyen K, DeSieno MA, Bae B, Johannes TW, Cobb RE, Zhao H, Nair SK. Characterization of the flavin monooxygenase involved in biosynthesis of the antimalarial FR-900098. Organic & Biomolecular Chemistry. PMID 30681110 DOI: 10.1039/C8Ob02840K  0.586
2015 Cobb RE, Bae B, Li Z, DeSieno MA, Nair SK, Zhao H. Structure-guided design and biosynthesis of a novel FR-900098 analogue as a potent Plasmodium falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Dxr) inhibitor. Chemical Communications (Cambridge, England). 51: 2526-8. PMID 25567100 DOI: 10.1039/C4Cc09181G  0.475
2011 Bae B, Cobb RE, DeSieno MA, Zhao H, Nair SK. New N-acetyltransferase fold in the structure and mechanism of the phosphonate biosynthetic enzyme FrbF. The Journal of Biological Chemistry. 286: 36132-41. PMID 21865168 DOI: 10.1074/Jbc.M111.263533  0.469
2011 Desieno MA, Van Der Donk WA, Zhao H. Characterization and application of the Fe(ii) and α-ketoglutarate dependent hydroxylase FrbJ Chemical Communications. 47: 10025-10027. PMID 21829824 DOI: 10.1039/C1Cc13597J  0.394
2011 Desieno M, Du J, Zhao H. Altering Enzyme Substrate and Cofactor Specificity via Protein Engineering Protein Engineering Handbook, Volume 1 & Volume 2. 2: 777-796. DOI: 10.1002/9783527634026.ch31  0.322
2011 Desieno MA, Denard CA, Zhao H. Drug Discovery and Development by Combinatorial Biosynthesis Enzyme Technologies: Metagenomics, Evolution, Biocatalysis, and Biosynthesis. 251-283. DOI: 10.1002/9780470627303.ch8  0.545
2010 Johannes TW, DeSieno MA, Griffin BM, Thomas PM, Kelleher NL, Metcalf WW, Zhao H. Deciphering the late biosynthetic steps of antimalarial compound FR-900098. Chemistry & Biology. 17: 57-64. PMID 20142041 DOI: 10.1016/J.Chembiol.2009.12.009  0.594
2008 DeSieno MA, Johannes TW, Zhao H. Deciphering the late steps in FR900098 biosynthesis Aiche Annual Meeting, Conference Proceedings.  0.571
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