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Year Citation  Score
2022 Dousis A, Ravichandran K, Hobert EM, Moore MJ, Rabideau AE. An engineered T7 RNA polymerase that produces mRNA free of immunostimulatory byproducts. Nature Biotechnology. PMID 36357718 DOI: 10.1038/s41587-022-01525-6  0.3
2021 Kovalak C, Donovan S, Bicknell AA, Metkar M, Moore MJ. Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved alternative splicing nonsense-mediated decay pathways. Genome Biology. 22: 132. PMID 33941243 DOI: 10.1186/s13059-021-02309-y  0.36
2019 Mauger DM, Cabral BJ, Presnyak V, Su SV, Reid DW, Goodman B, Link K, Khatwani N, Reynders J, Moore MJ, McFadyen IJ. mRNA structure regulates protein expression through changes in functional half-life. Proceedings of the National Academy of Sciences of the United States of America. PMID 31712433 DOI: 10.1073/Pnas.1908052116  0.404
2019 Saini H, Bicknell AA, Eddy SR, Moore MJ. Free circular introns with an unusual branchpoint in neuronal projections. Elife. 8. PMID 31697236 DOI: 10.7554/Elife.47809  0.776
2019 Kucukural A, Yukselen O, Ozata DM, Moore MJ, Garber M. DEBrowser: interactive differential expression analysis and visualization tool for count data. Bmc Genomics. 20: 6. PMID 30611200 DOI: 10.1186/S12864-018-5362-X  0.38
2019 Saini H, Bicknell AA, Eddy SR, Moore MJ. Author response: Free circular introns with an unusual branchpoint in neuronal projections Elife. DOI: 10.7554/Elife.47809.Sa2  0.735
2018 Turanov AA, Lo A, Hassler MR, Makris A, Ashar-Patel A, Alterman JF, Coles AH, Haraszti RA, Roux L, Godinho BMDC, Echeverria D, Pears S, Iliopoulos J, Shanmugalingam R, Ogle R, ... ... Moore MJ, et al. RNAi modulation of placental sFLT1 for the treatment of preeclampsia. Nature Biotechnology. PMID 30451990 DOI: 10.1038/Nbt.4297  0.328
2018 Metkar M, Ozadam H, Lajoie BR, Imakaev M, Mirny LA, Dekker J, Moore MJ. Higher-Order Organization Principles of Pre-translational mRNPs. Molecular Cell. 72: 715-726.e3. PMID 30415953 DOI: 10.1016/J.Molcel.2018.09.012  0.465
2018 Didiot MC, Ferguson CM, Ly S, Coles AH, Smith AO, Bicknell AA, Hall LM, Sapp E, Echeverria D, Pai AA, DiFiglia M, Moore MJ, Hayward LJ, Aronin N, Khvorova A. Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin. Cell Reports. 24: 2553-2560.e5. PMID 30184490 DOI: 10.1016/J.Celrep.2018.07.106  0.408
2018 Jain R, Frederick JP, Huang EY, Burke KE, Mauger DM, Andrianova EA, Farlow SJ, Siddiqui S, Pimentel J, Cheung-Ong K, McKinney KM, Köhrer C, Moore MJ, Chakraborty T. MicroRNAs Enable mRNA Therapeutics to Selectively Program Cancer Cells to Self-Destruct. Nucleic Acid Therapeutics. PMID 30088967 DOI: 10.1089/Nat.2018.0734  0.354
2018 Braun JE, Friedman LJ, Gelles J, Moore MJ. Synergistic assembly of human pre-spliceosomes across introns and exons. Elife. 7. PMID 29932423 DOI: 10.7554/Elife.37751  0.733
2018 Chen W, Moore J, Ozadam H, Shulha HP, Rhind N, Weng Z, Moore MJ. Transcriptome-wide Interrogation of the Functional Intronome by Spliceosome Profiling. Cell. 173: 1031-1044.e13. PMID 29727662 DOI: 10.1016/J.Cell.2018.03.062  0.46
2018 Hassler MR, Turanov AA, Alterman JF, Haraszti RA, Coles AH, Osborn MF, Echeverria D, Nikan M, Salomon WE, Roux L, Godinho BMDC, Davis SM, Morrissey DV, Zamore PD, Karumanchi SA, ... Moore MJ, et al. Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo. Nucleic Acids Research. PMID 29432571 DOI: 10.1093/Nar/Gky037  0.335
2018 Braun JE, Friedman LJ, Gelles J, Moore MJ. Author response: Synergistic assembly of human pre-spliceosomes across introns and exons Elife. DOI: 10.7554/Elife.37751.044  0.579
2018 Mou H, Smith J, Peng L, Yin H, Moore J, Zhang X, Song C, Sheel A, Wu Q, Ozata D, Li Y, Anderson D, Emerson C, Moore M, Weng Z, et al. Abstract 3374: CRISPR/Cas9 mediated genome editing induces exon skipping by alternative splicing or exon deletion Cancer Research. 78: 3374-3374. DOI: 10.1158/1538-7445.Am2018-3374  0.351
2017 Limoncelli KA, Merrikh CN, Moore MJ. ASC1 and RPS3: New actors in 18S non-functional rRNA decay. Rna (New York, N.Y.). PMID 28956756 DOI: 10.1261/Rna.061671.117  0.381
2017 Ashar-Patel A, Kaymaz Y, Rajakumar A, Bailey JA, Karumanchi SA, Moore MJ. FLT1 and transcriptome-wide polyadenylation site (PAS) analysis in preeclampsia. Scientific Reports. 7: 12139. PMID 28939845 DOI: 10.1038/S41598-017-11639-6  0.432
2017 Mou H, Smith JL, Peng L, Yin H, Moore J, Zhang XO, Song CQ, Sheel A, Wu Q, Ozata DM, Li Y, Anderson DG, Emerson CP, Sontheimer EJ, Moore MJ, et al. CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion. Genome Biology. 18: 108. PMID 28615073 DOI: 10.1186/S13059-017-1237-8  0.356
2017 Cenik C, Chua HN, Singh G, Akef A, Snyder MP, Palazzo AF, Moore MJ, Roth FP. A common class of transcripts with 5'-intron depletion, distinct early coding sequence features, and N(1)-methyladenosine modification. Rna (New York, N.Y.). 23: 270-283. PMID 27994090 DOI: 10.1261/Rna.059105.116  0.784
2016 Atianand MK, Hu W, Satpathy AT, Shen Y, Ricci EP, Alvarez-Dominguez JR, Bhatta A, Schattgen SA, McGowan JD, Blin J, Braun JE, Gandhi P, Moore MJ, Chang HY, Lodish HF, et al. A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation. Cell. 165: 1672-85. PMID 27315481 DOI: 10.1016/J.Cell.2016.05.075  0.562
2016 Serebrov V, Moore MJ. Single Molecule Approaches in RNA-Protein Interactions. Advances in Experimental Medicine and Biology. 907: 89-106. PMID 27256383 DOI: 10.1007/978-3-319-29073-7_4  0.407
2016 Hoskins AA, Rodgers ML, Friedman LJ, Gelles J, Moore MJ. Single molecule analysis reveals reversible and irreversible steps during spliceosome activation. Elife. 5. PMID 27244240 DOI: 10.7554/Elife.14166  0.763
2016 Heyer EE, Moore MJ. Redefining the Translational Status of 80S Monosomes. Cell. 164: 757-69. PMID 26871635 DOI: 10.1016/J.Cell.2016.01.003  0.432
2016 Sharma U, Conine CC, Shea JM, Boskovic A, Derr AG, Bing XY, Belleannee C, Kucukural A, Serra RW, Sun F, Song L, Carone BR, Ricci EP, Li XZ, Fauquier L, ... Moore MJ, et al. Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. Science (New York, N.Y.). 351: 391-6. PMID 26721685 DOI: 10.1126/Science.Aad6780  0.39
2016 Hoskins AA, Rodgers ML, Friedman LJ, Gelles J, Moore MJ. Author response: Single molecule analysis reveals reversible and irreversible steps during spliceosome activation Elife. DOI: 10.7554/Elife.14166.030  0.577
2016 Ashar A, Kaymaz Y, Rajakumar A, Bailey JA, Karumanchi SA, Moore MJ. 63 Transcriptome wide profiling of mRNA 3′-ends in preeclampsia using PAS-SEQ Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 6: 208-209. DOI: 10.1016/J.Preghy.2016.08.145  0.372
2015 Salomon WE, Jolly SM, Moore MJ, Zamore PD, Serebrov V. Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides. Cell. 162: 84-95. PMID 26140592 DOI: 10.1016/J.Cell.2015.06.029  0.382
2015 Roy CK, Olson S, Graveley BR, Zamore PD, Moore MJ. Assessing long-distance RNA sequence connectivity via RNA-templated DNA-DNA ligation. Elife. 4. PMID 25866926 DOI: 10.7554/Elife.03700  0.445
2015 Singh G, Pratt G, Yeo GW, Moore MJ. The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion. Annual Review of Biochemistry. 84: 325-54. PMID 25784054 DOI: 10.1146/Annurev-Biochem-080111-092106  0.768
2015 Moore MJ. Twenty years of technology. Rna (New York, N.Y.). 21: 697-8. PMID 25780196 DOI: 10.1261/Rna.051052.115  0.473
2015 Heyer EE, Ozadam H, Ricci EP, Cenik C, Moore MJ. An optimized kit-free method for making strand-specific deep sequencing libraries from RNA fragments. Nucleic Acids Research. 43: e2. PMID 25505164 DOI: 10.1093/Nar/Gku1235  0.388
2014 Carpenter S, Ricci EP, Mercier BC, Moore MJ, Fitzgerald KA. Post-transcriptional regulation of gene expression in innate immunity. Nature Reviews. Immunology. 14: 361-76. PMID 24854588 DOI: 10.1038/Nri3682  0.343
2014 Chen W, Moore MJ. The spliceosome: disorder and dynamics defined. Current Opinion in Structural Biology. 24: 141-9. PMID 24530854 DOI: 10.1016/J.Sbi.2014.01.009  0.39
2014 Chen W, Shulha HP, Ashar-Patel A, Yan J, Green KM, Query CC, Rhind N, Weng Z, Moore MJ. Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes. Rna (New York, N.Y.). 20: 308-20. PMID 24442611 DOI: 10.1261/Rna.040980.113  0.371
2014 Moore MJ, Zhang C, Gantman EC, Mele A, Darnell JC, Darnell RB. Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis. Nature Protocols. 9: 263-93. PMID 24407355 DOI: 10.1038/Nprot.2014.012  0.316
2014 Ricci EP, Kucukural A, Cenik C, Mercier BC, Singh G, Heyer EE, Ashar-Patel A, Peng L, Moore MJ. Staufen1 senses overall transcript secondary structure to regulate translation. Nature Structural & Molecular Biology. 21: 26-35. PMID 24336223 DOI: 10.1038/Nsmb.2739  0.766
2014 Singh G, Ricci EP, Moore MJ. RIPiT-Seq: a high-throughput approach for footprinting RNA:protein complexes. Methods (San Diego, Calif.). 65: 320-32. PMID 24096052 DOI: 10.1016/J.Ymeth.2013.09.013  0.75
2014 Roy CK, Olson S, Graveley BR, Zamore PD, Moore MJ. Author response: Assessing long-distance RNA sequence connectivity via RNA-templated DNA–DNA ligation Elife. DOI: 10.7554/Elife.03700.022  0.374
2013 Shcherbakova I, Hoskins AA, Friedman LJ, Serebrov V, Corrêa IR, Xu MQ, Gelles J, Moore MJ. Alternative spliceosome assembly pathways revealed by single-molecule fluorescence microscopy. Cell Reports. 5: 151-65. PMID 24075986 DOI: 10.1016/J.Celrep.2013.08.026  0.781
2013 Kucukural A, Özadam H, Singh G, Moore MJ, Cenik C. ASPeak: an abundance sensitive peak detection algorithm for RIP-Seq. Bioinformatics (Oxford, England). 29: 2485-6. PMID 23929032 DOI: 10.1093/Bioinformatics/Btt428  0.723
2013 Carpenter S, Aiello D, Atianand MK, Ricci EP, Gandhi P, Hall LL, Byron M, Monks B, Henry-Bezy M, Lawrence JB, O'Neill LA, Moore MJ, Caffrey DR, Fitzgerald KA. A long noncoding RNA mediates both activation and repression of immune response genes. Science (New York, N.Y.). 341: 789-92. PMID 23907535 DOI: 10.1126/Science.1240925  0.355
2013 Li XZ, Roy CK, Moore MJ, Zamore PD. Defining piRNA primary transcripts. Cell Cycle (Georgetown, Tex.). 12: 1657-8. PMID 23673320 DOI: 10.4161/Cc.24989  0.437
2013 Jokhi V, Ashley J, Nunnari J, Noma A, Ito N, Wakabayashi-Ito N, Moore MJ, Budnik V. Torsin mediates primary envelopment of large ribonucleoprotein granules at the nuclear envelope. Cell Reports. 3: 988-95. PMID 23583177 DOI: 10.1016/J.Celrep.2013.03.015  0.336
2013 Crawford DJ, Hoskins AA, Friedman LJ, Gelles J, Moore MJ. Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site. Proceedings of the National Academy of Sciences of the United States of America. 110: 6783-8. PMID 23569281 DOI: 10.1073/Pnas.1219305110  0.783
2013 Li XZ, Roy CK, Dong X, Bolcun-Filas E, Wang J, Han BW, Xu J, Moore MJ, Schimenti JC, Weng Z, Zamore PD. An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes. Molecular Cell. 50: 67-81. PMID 23523368 DOI: 10.1016/J.Molcel.2013.02.016  0.43
2013 Wang Q, Moore MJ, Adelmant G, Marto JA, Silver PA. PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth. Genes & Development. 27: 615-26. PMID 23512658 DOI: 10.1101/Gad.212308.112  0.34
2013 Carpenter S, Atianand M, Aiello D, Ricci E, Gandhi P, Hall LL, Byron M, Monks B, Henry-Bezy M, O’Neill LA, B.Lawrence J, Moore MJ, Caffrey DR, Fitzgerald KA. 34 Cytokine. 63: 251. DOI: 10.1016/J.Cyto.2013.06.037  0.347
2012 Singh G, Kucukural A, Cenik C, Leszyk JD, Shaffer SA, Weng Z, Moore MJ. The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus. Cell. 151: 915-916. PMID 30360293 DOI: 10.1016/j.cell.2012.10.032  0.666
2012 Bicknell AA, Cenik C, Chua HN, Roth FP, Moore MJ. Introns in UTRs: why we should stop ignoring them. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 34: 1025-34. PMID 23108796 DOI: 10.1002/Bies.201200073  0.372
2012 Singh G, Kucukural A, Cenik C, Leszyk JD, Shaffer SA, Weng Z, Moore MJ. The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. Cell. 151: 750-64. PMID 23084401 DOI: 10.1016/J.Cell.2012.10.007  0.758
2012 Speese SD, Ashley J, Jokhi V, Nunnari J, Barria R, Li Y, Ataman B, Koon A, Chang YT, Li Q, Moore MJ, Budnik V. Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic Wnt signaling. Cell. 149: 832-46. PMID 22579286 DOI: 10.1016/J.Cell.2012.10.003  0.329
2012 Hoskins AA, Moore MJ. The spliceosome: a flexible, reversible macromolecular machine. Trends in Biochemical Sciences. 37: 179-88. PMID 22480731 DOI: 10.1016/J.Tibs.2012.02.009  0.696
2012 Hoskins AA, Friedman LJ, Crawford DJ, Anderson EJ, Shcherbakova I, Cornish VW, Gelles J, Moore MJ. Into the CoSMoS: Single Molecule Analysis of Spliceosome Assembly and Activation Biophysical Journal. 102: 610a. DOI: 10.1016/J.Bpj.2011.11.3324  0.659
2012 Hoskins A, Friedman L, Correa I, Xu M, Cornish VW, Gelles J, Moore MJ. Turning on the Spliceosome Biophysical Journal. 102: 602a. DOI: 10.1016/J.Bpj.2011.11.3278  0.662
2011 Morello LG, Coltri PP, Quaresma AJ, Simabuco FM, Silva TC, Singh G, Nickerson JA, Oliveira CC, Moore MJ, Zanchin NI. The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processing. Plos One. 6: e29174. PMID 22195017 DOI: 10.1371/Journal.Pone.0029174  0.729
2011 Hoskins AA, Gelles J, Moore MJ. New insights into the spliceosome by single molecule fluorescence microscopy. Current Opinion in Chemical Biology. 15: 864-70. PMID 22057211 DOI: 10.1016/J.Cbpa.2011.10.010  0.788
2011 Cenik C, Chua HN, Zhang H, Tarnawsky SP, Akef A, Derti A, Tasan M, Moore MJ, Palazzo AF, Roth FP. Genome analysis reveals interplay between 5'UTR introns and nuclear mRNA export for secretory and mitochondrial genes. Plos Genetics. 7: e1001366. PMID 21533221 DOI: 10.1371/Journal.Pgen.1001366  0.707
2011 Hoskins AA, Friedman LJ, Gallagher SS, Crawford DJ, Anderson EG, Wombacher R, Ramirez N, Cornish VW, Gelles J, Moore MJ. Ordered and dynamic assembly of single spliceosomes. Science (New York, N.Y.). 331: 1289-95. PMID 21393538 DOI: 10.1126/Science.1198830  0.783
2011 Sephton CF, Cenik C, Kucukural A, Dammer EB, Cenik B, Han Y, Dewey CM, Roth FP, Herz J, Peng J, Moore MJ, Yu G. Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes. The Journal of Biological Chemistry. 286: 1204-15. PMID 21051541 DOI: 10.1074/Jbc.M110.190884  0.448
2011 Crawford DJ, Friedman LJ, Hoskins AA, Gelles J, Moore MJ. Direct Observation of pre-mRNA Arrangements During Spliceosome Assembly Using Single Molecule FRET Biophysical Journal. 100: 233a. DOI: 10.1016/J.Bpj.2010.12.1488  0.69
2011 Hoskins A, Friedman L, Gallagher SS, Crawford DJ, Anderson EG, Wombacher R, Ramirez N, Cornish VW, Gelles J, Moore MJ. Dynamic and Ordered Assembly of Single Spliceosomes Biophysical Journal. 100: 233a. DOI: 10.1016/J.Bpj.2010.12.1487  0.659
2010 Lemmens R, Moore MJ, Al-Chalabi A, Brown RH, Robberecht W. RNA metabolism and the pathogenesis of motor neuron diseases. Trends in Neurosciences. 33: 249-58. PMID 20227117 DOI: 10.1016/J.Tins.2010.02.003  0.36
2009 Albert BJ, McPherson PA, O'Brien K, Czaicki NL, Destefino V, Osman S, Li M, Day BW, Grabowski PJ, Moore MJ, Vogt A, Koide K. Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells. Molecular Cancer Therapeutics. 8: 2308-18. PMID 19671752 DOI: 10.1158/1535-7163.Mct-09-0051  0.369
2009 Cole SE, LaRiviere FJ, Merrikh CN, Moore MJ. A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decay. Molecular Cell. 34: 440-50. PMID 19481524 DOI: 10.1016/J.Molcel.2009.04.017  0.429
2009 Moore MJ, Proudfoot NJ. Pre-mRNA processing reaches back to transcription and ahead to translation. Cell. 136: 688-700. PMID 19239889 DOI: 10.1016/J.Cell.2009.02.001  0.416
2008 Bramham CR, Worley PF, Moore MJ, Guzowski JF. The immediate early gene arc/arg3.1: regulation, mechanisms, and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11760-7. PMID 19005037 DOI: 10.1523/Jneurosci.3864-08.2008  0.366
2008 O'Brien K, Matlin AJ, Lowell AM, Moore MJ. The biflavonoid isoginkgetin is a general inhibitor of Pre-mRNA splicing. The Journal of Biological Chemistry. 283: 33147-54. PMID 18826947 DOI: 10.1074/Jbc.M805556200  0.384
2008 Rozovsky N, Butterworth AC, Moore MJ. Interactions between eIF4AI and its accessory factors eIF4B and eIF4H. Rna (New York, N.Y.). 14: 2136-48. PMID 18719248 DOI: 10.1261/Rna.1049608  0.445
2008 Crawford DJ, Hoskins AA, Friedman LJ, Gelles J, Moore MJ. Visualizing the splicing of single pre-mRNA molecules in whole cell extract. Rna (New York, N.Y.). 14: 170-9. PMID 18025254 DOI: 10.1261/Rna.794808  0.775
2007 Matlin AJ, Moore MJ. Spliceosome assembly and composition. Advances in Experimental Medicine and Biology. 623: 14-35. PMID 18380338 DOI: 10.1007/978-0-387-77374-2_2  0.414
2007 Giorgi C, Yeo GW, Stone ME, Katz DB, Burge C, Turrigiano G, Moore MJ. The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression. Cell. 130: 179-91. PMID 17632064 DOI: 10.1016/J.Cell.2007.05.028  0.607
2007 Giorgi C, Moore MJ. The nuclear nurture and cytoplasmic nature of localized mRNPs. Seminars in Cell & Developmental Biology. 18: 186-93. PMID 17459736 DOI: 10.1016/J.Semcdb.2007.01.002  0.459
2006 LaRiviere FJ, Cole SE, Ferullo DJ, Moore MJ. A late-acting quality control process for mature eukaryotic rRNAs. Molecular Cell. 24: 619-26. PMID 17188037 DOI: 10.1016/J.Molcel.2006.10.008  0.447
2006 Stroupe ME, Tange TØ, Thomas DR, Moore MJ, Grigorieff N. The three-dimensional arcitecture of the EJC core. Journal of Molecular Biology. 360: 743-9. PMID 16797590 DOI: 10.1016/J.Jmb.2006.05.049  0.439
2006 Shibuya T, Tange TØ, Stroupe ME, Moore MJ. Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay. Rna (New York, N.Y.). 12: 360-74. PMID 16495234 DOI: 10.1261/Rna.2190706  0.484
2005 Tange TØ, Shibuya T, Jurica MS, Moore MJ. Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core. Rna (New York, N.Y.). 11: 1869-83. PMID 16314458 DOI: 10.1261/Rna.2155905  0.464
2005 Schroder PA, Moore MJ. Association of ribosomal proteins with nascent transcripts in S. cerevisiae. Rna (New York, N.Y.). 11: 1521-9. PMID 16199762 DOI: 10.1261/Rna.2134305  0.448
2005 Moore MJ. From birth to death: the complex lives of eukaryotic mRNAs. Science (New York, N.Y.). 309: 1514-8. PMID 16141059 DOI: 10.1126/Science.1111443  0.426
2004 Du H, Tardiff DF, Moore MJ, Rosbash M. Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation. Proceedings of the National Academy of Sciences of the United States of America. 101: 14841-6. PMID 15465910 DOI: 10.1073/Pnas.0406319101  0.343
2004 Tange TØ, Nott A, Moore MJ. The ever-increasing complexities of the exon junction complex. Current Opinion in Cell Biology. 16: 279-84. PMID 15145352 DOI: 10.1016/J.Ceb.2004.03.012  0.424
2004 Shibuya T, Tange TØ, Sonenberg N, Moore MJ. eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay. Nature Structural & Molecular Biology. 11: 346-51. PMID 15034551 DOI: 10.1038/Nsmb750  0.483
2004 Jurica MS, Sousa D, Moore MJ, Grigorieff N. Three-dimensional structure of C complex spliceosomes by electron microscopy. Nature Structural & Molecular Biology. 11: 265-9. PMID 14981503 DOI: 10.1038/Nsmb728  0.403
2004 Nott A, Le Hir H, Moore MJ. Splicing enhances translation in mammalian cells: an additional function of the exon junction complex. Genes & Development. 18: 210-22. PMID 14752011 DOI: 10.1101/Gad.1163204  0.444
2003 Jurica MS, Moore MJ. Pre-mRNA splicing: awash in a sea of proteins. Molecular Cell. 12: 5-14. PMID 12887888 DOI: 10.1016/S1097-2765(03)00270-3  0.378
2003 Le Hir H, Nott A, Moore MJ. How introns influence and enhance eukaryotic gene expression. Trends in Biochemical Sciences. 28: 215-20. PMID 12713906 DOI: 10.1016/S0968-0004(03)00052-5  0.329
2003 Nott A, Meislin SH, Moore MJ. A quantitative analysis of intron effects on mammalian gene expression. Rna (New York, N.Y.). 9: 607-17. PMID 12702819 DOI: 10.1261/Rna.5250403  0.408
2002 Jurica MS, Moore MJ. Capturing splicing complexes to study structure and mechanism. Methods (San Diego, Calif.). 28: 336-45. PMID 12431437 DOI: 10.1016/S1046-2023(02)00240-2  0.406
2002 Reichert VL, Le Hir H, Jurica MS, Moore MJ. 5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly. Genes & Development. 16: 2778-91. PMID 12414731 DOI: 10.1101/Gad.1030602  0.475
2002 Moore MJ. RNA events. No end to nonsense. Science (New York, N.Y.). 298: 370-1. PMID 12376689 DOI: 10.1126/Science.1078096  0.424
2002 Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. Rna (New York, N.Y.). 8: 426-39. PMID 11991638 DOI: 10.1017/S1355838202021088  0.397
2002 Moore M. Nuclear RNA turnover. Cell. 108: 431-4. PMID 11909514 DOI: 10.1016/S0092-8674(02)00645-1  0.399
2001 Moore MJ, Rosbash M. Cell biology. TAPping into mRNA export. Science (New York, N.Y.). 294: 1841-2. PMID 11729289 DOI: 10.1126/Science.1067676  0.337
2001 Le Hir H, Gatfield D, Izaurralde E, Moore MJ. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay Embo Journal. 20: 4987-4997. PMID 11532962 DOI: 10.1093/Emboj/20.17.4987  0.646
2001 Mühlemann O, Mock-Casagrande CS, Wang J, Li S, Custódio N, Carmo-Fonseca M, Wilkinson MF, Moore MJ. Precursor RNAs harboring nonsense codons accumulate near the site of transcription. Molecular Cell. 8: 33-43. PMID 11511358 DOI: 10.1016/S1097-2765(01)00288-X  0.465
2000 Le Hir H, Izaurralde E, Maquat LE, Moore MJ. The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions Embo Journal. 19: 6860-6869. PMID 11118221 DOI: 10.1093/Emboj/19.24.6860  0.643
2000 Bar-Shalom A, Moore MJ. Tri-partite assay for studying exon ligation by the ai5gamma group II intron. Biochemistry. 39: 10207-18. PMID 10956010 DOI: 10.1021/Bi000808W  0.372
2000 Moore MJ, Query CC. Joining of RNAs by splinted ligation Methods in Enzymology. 317: 109-123. PMID 10829275 DOI: 10.1016/S0076-6879(00)17009-0  0.381
2000 Le Hir H, Moore MJ, Maquat LE. Pre-mRNA splicing alters mRNP composition: Evidence for stable association of proteins at exon-exon junctions Genes and Development. 14: 1098-1108. PMID 10809668 DOI: 10.1101/Gad.14.9.1098  0.431
2000 Anderson K, Moore MJ. Bimolecular exon ligation by the human spliceosome bypasses early 3' splice site AG recognition and requires NTP hydrolysis. Rna. 6: 16-25. PMID 10668795 DOI: 10.1017/S1355838200001862  0.396
2000 Chen S, Anderson K, Moore MJ. Evidence for a linear search in bimolecular 3′ splice site AG selection Proceedings of the National Academy of Sciences of the United States of America. 97: 593-598. PMID 10639124 DOI: 10.1073/Pnas.97.2.593  0.417
2000 Moore MJ. Intron recognition comes of AGe Nature Structural Biology. 7: 14-16. PMID 10625417 DOI: 10.1038/71207  0.355
2000 Reichert V, Moore MJ. Better conditions for mammalian in vitro splicing provided by acetate and glutamate as potassium counterions Nucleic Acids Research. 28: 416-423. PMID 10606638 DOI: 10.1093/Nar/28.2.416  0.358
1999 Moore MJ. Joining RNA molecules with T4 DNA ligase Methods in Molecular Biology (Clifton, N.J.). 118: 11-19. PMID 10549511 DOI: 10.1385/1-59259-676-2:11  0.323
1999 Luo HR, Moreau GA, Levin N, Moore MJ. The human Prp8 protein is a component of both U2- and U12-dependent spliceosomes. Rna (New York, N.Y.). 5: 893-908. PMID 10411133 DOI: 10.1017/S1355838299990520  0.365
1999 Reyes JL, Gustafson EH, Luo HR, Moore MJ, Konarska MM. The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5' splice site. Rna (New York, N.Y.). 5: 167-79. PMID 10024169 DOI: 10.1017/S1355838299981785  0.665
1997 Anderson K, Moore MJ. Bimolecular Exon Ligation by the Human Spliceosome Science. 276: 1712-1716. PMID 9180084 DOI: 10.1126/Science.276.5319.1712  0.457
1996 Hinz M, Moore MJ, Bindereif A. Domain Analysis of Human U5 RNA CAP TRIMETHYLATION, PROTEIN BINDING, AND SPLICEOSOME ASSEMBLY Journal of Biological Chemistry. 271: 19001-19007. PMID 8702566 DOI: 10.1074/Jbc.271.31.19001  0.435
1994 Query CC, Moore MJ, Sharp PA. Branch nucleophile selection in pre-mRNA splicing: evidence for the bulged duplex model. Genes & Development. 8: 587-97. PMID 7926752 DOI: 10.1101/Gad.8.5.587  0.587
1993 Moore MJ, Sharp PA. Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing. Nature. 365: 364-8. PMID 8397340 DOI: 10.1038/365364A0  0.585
1993 Moore MJ, Query CC, Sharp PA. 13 Splicing of Precursors to mRNA by the Spliceosome Cold Spring Harbor Monograph Archive. 24: 303-357. DOI: 10.1101/087969380.24.303  0.591
1992 Moore MJ, Sharp PA. Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites. Science (New York, N.Y.). 256: 992-7. PMID 1589782 DOI: 10.1126/Science.1589782  0.581
1992 Moore MJ, Miller SM, Walsh CT. C-terminal cysteines of Tn501 mercuric ion reductase. Biochemistry. 31: 1677-85. PMID 1531297 DOI: 10.1021/Bi00121A015  0.47
1991 Schiering N, Kabsch W, Moore MJ, Distefano MD, Walsh CT, Pai EF. Structure of the detoxification catalyst mercuric ion reductase from Bacillus sp. strain RC607. Nature. 352: 168-72. PMID 2067577 DOI: 10.1038/352168A0  0.616
1990 Miller SM, Massey V, Ballou D, Williams CH, Distefano MD, Moore MJ, Walsh CT. Use of a site-directed triple mutant to trap intermediates: demonstration that the flavin C(4a)-thiol adduct and reduced flavin are kinetically competent intermediates in mercuric ion reductase. Biochemistry. 29: 2831-41. PMID 2189497 DOI: 10.1021/Bi00463A028  0.614
1990 Distefano MD, Moore MJ, Walsh CT. Active site of mercuric reductase resides at the subunit interface and requires Cys135 and Cys140 from one subunit and Cys558 and Cys559 from the adjacent subunit: evidence from in vivo and in vitro heterodimer formation. Biochemistry. 29: 2703-13. PMID 2189495 DOI: 10.1021/Bi00463A013  0.646
1990 Moore MJ, Distefano MD, Zydowsky LD, Cummings RT, Walsh CT. Organomercurial lyase and mercuric ion reductase: nature's mercury detoxification catalysts Accounts of Chemical Research. 23: 301-308. DOI: 10.1021/Ar00177A006  0.59
1990 MOORE MJ, DISTEFANO MD, ZYDOWSKY LD, CUMMINGS RT, WALSH CT. ChemInform Abstract: Organomercurial Lyase and Mercuric Ion Reductase: Nature′s Mercury Detoxification Catalysts Cheminform. 21. DOI: 10.1002/chin.199052385  0.527
1989 Miller SM, Moore MJ, Massey V, Williams CH, Distefano MD, Ballou DP, Walsh CT. Evidence for the participation of Cys558 and Cys559 at the active site of mercuric reductase. Biochemistry. 28: 1194-205. PMID 2653437 DOI: 10.1021/Bi00429A037  0.629
1989 Moore MJ, Walsh CT. Mutagenesis of the N- and C-terminal cysteine pairs of Tn501 mercuric ion reductase: Consequences for bacterial detoxification of mercurials Biochemistry. 28: 1183-1194. PMID 2540817 DOI: 10.1021/Bi00429A036  0.467
1989 Moore M, Distefano M, Walsh C. Catalytic mercury reduction by the detoxification enzyme, mercuric ion reductase, requires four active site cysteines located at the subunit interface Journal of Inorganic Biochemistry. 36: 240. DOI: 10.1016/0162-0134(89)84276-X  0.582
1988 Walsh C, Distefano M, Moore M. Mutagenesis of paired cysteine residues in the disulphide-containing flavoprotein mercuric ion reductase from mercury-resistant bacteria. Biochemical Society Transactions. 16: 90-1. PMID 3371539 DOI: 10.1042/Bst0160090  0.583
1988 Walsh CT, Distefano MD, Moore MJ, Shewchuk LM, Verdine GL. Molecular basis of bacterial resistance to organomercurial and inorganic mercuric salts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2: 124-30. PMID 3277886 DOI: 10.1096/Fasebj.2.2.3277886  0.701
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