| Year |
Citation |
Score |
| 2019 |
Kuan KKW, Markwell-Heys AW, Cruickshank MC, Tran DP, Adlington RM, Baldwin JE, George JH. Biomimetic synthetic studies on meroterpenoids from the marine sponge Aka coralliphaga: Divergent total syntheses of siphonodictyal B, liphagal and corallidictyals A-D. Bioorganic & Medicinal Chemistry. PMID 30992205 DOI: 10.1016/J.Bmc.2019.02.038 |
0.535 |
|
| 2018 |
Lee V, He J, Baldwin J. Studies towards the Synthesis of the Antibiotic Tetrodecamycin Synlett. 29: 1117-1121. DOI: 10.1055/S-0037-1609303 |
0.407 |
|
| 2017 |
McNeill L, Brown T, Sami M, Clifton I, Burzlaff N, Claridge T, Adlington R, Baldwin J, Rutledge PJ, Schofield C. Terminally truncated isopenicillin N synthase generates a dithioester product: evidence for a thioaldehyde intermediate and a new mode of reaction for non-heme iron oxidases. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28703303 DOI: 10.1002/Chem.201701592 |
0.816 |
|
| 2015 |
Tchabanenko K, Chesworth R, Parker JS, Anand NK, Russell AT, Adlington RM, Baldwin JE. Retraction notice to "Biomimetic approach to Galbulimina type I alkaloids" [Tetrahedron 61 (2005) 11649-11656] Tetrahedron. DOI: 10.1016/J.Tet.2015.12.025 |
0.468 |
|
| 2013 |
Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding site Febs Letters. 587: 2705-2709. PMID 23860486 DOI: 10.1016/J.Febslet.2013.07.016 |
0.802 |
|
| 2013 |
Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues δ-(L-α-Aminoadipoyl)-L-homocysteinyl-D-Xaa Characterised by Protein Crystallography Chembiochem. 14: 599-606. PMID 23468426 DOI: 10.1002/Cbic.201200728 |
0.804 |
|
| 2013 |
Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of isopenicillin N synthase with a dipeptide substrate analogue Archives of Biochemistry and Biophysics. 530: 48-53. PMID 23262315 DOI: 10.1016/J.Abb.2012.12.012 |
0.8 |
|
| 2012 |
Jones MW, Baldwin JE, Cowley AR, Dilworth JR, Karpov A, Smiljanic N, Thompson AL, Adlington RM. Synthesis of new bulky bis(pyrazolyl)methane carboxylate (heteroscorpionate) ligands and their complexes with iron, manganese and nickel. Dalton Transactions (Cambridge, England : 2003). 41: 14068-86. PMID 23064694 DOI: 10.1039/C2Dt31859H |
0.528 |
|
| 2011 |
Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of isopenicillin N synthase with δ-(l-α- aminoadipoyl)-l-cysteinyl-d-methionine reveals thioether coordination to iron Archives of Biochemistry and Biophysics. 516: 103-107. PMID 22001738 DOI: 10.1016/J.Abb.2011.09.014 |
0.806 |
|
| 2011 |
Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. Isopenicillin N Synthase Binds δ-(L-α-Aminoadipoyl)-L-Cysteinyl-D-Thia-allo-Isoleucine through both Sulfur Atoms Chembiochem. 12: 1881-1885. PMID 21678539 DOI: 10.1002/Cbic.201100149 |
0.807 |
|
| 2010 |
Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Crystallographic studies on the binding of selectively deuterated LLD- and LLL-substrate epimers by isopenicillin N synthase Biochemical and Biophysical Research Communications. 398: 659-664. PMID 20603104 DOI: 10.1016/J.Bbrc.2010.06.129 |
0.806 |
|
| 2010 |
George JH, Hesse MD, Baldwin JE, Adlington RM. Biomimetic synthesis of polycyclic polyprenylated acylphloroglucinol natural products isolated from hypericum papuanum Organic Letters. 12: 3532-3535. PMID 20590087 DOI: 10.1021/Ol101380A |
0.486 |
|
| 2010 |
George JH, Baldwin JE, Adlington RM. Enantiospecific, biosynthetically inspired formal total synthesis of (+)-liphagal Organic Letters. 12: 2394-2397. PMID 20394432 DOI: 10.1021/Ol100756Z |
0.542 |
|
| 2010 |
Lawrence AL, Adlington RM, Baldwin JE, Lee V, Kershaw JA, Thompson AL. A short biomimetic synthesis of the meroterpenoids guajadial and psidial A. Organic Letters. 12: 1676-9. PMID 20235528 DOI: 10.1021/Ol100138K |
0.566 |
|
| 2010 |
Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of an LLL-configured depsipeptide substrate analogue bound to isopenicillin N synthase Organic and Biomolecular Chemistry. 8: 122-127. PMID 20024142 DOI: 10.1039/B910170E |
0.814 |
|
| 2010 |
George JH, McArdle M, Baldwin JE, Adlington RM. Biomimetic rearrangements of simplified labdane diterpenoids Tetrahedron. 66: 6321-6330. DOI: 10.1016/J.Tet.2010.05.052 |
0.559 |
|
| 2010 |
Jones MW, Adlington RM, Baldwin JE, Le Pevelen DD, Smiljanic N. New mononuclear Pd(II) complexes of sterically hindered bispyrazolylmethanes Inorganica Chimica Acta. 363: 1097-1101. DOI: 10.1016/J.Ica.2009.09.016 |
0.526 |
|
| 2010 |
BALDWIN JE, SPRING DR, ATKINSON CE, LEE V. ChemInform Abstract: Efficient Synthesis of the Sponge Alkaloids Cyclostellettamines A-F. Cheminform. 30: no-no. DOI: 10.1002/chin.199911249 |
0.449 |
|
| 2010 |
ADLINGTON RM, BALDWIN JE, CHALLIS GL. ChemInform Abstract: Rate Enhancement in the Reduction of (2,3)-α- and (2,3)-β-Methylenepenam β-Sulfoxides. Cheminform. 30: no-no. DOI: 10.1002/chin.199906227 |
0.453 |
|
| 2010 |
FEKNER T, BALDWIN JE, ADLINGTON RM, SCHOFIELD CJ. ChemInform Abstract: Unusually Stable Azetidinone Sulfenic Acids. Cheminform. 29: no-no. DOI: 10.1002/chin.199850126 |
0.398 |
|
| 2010 |
WALTER MW, ADLINGTON RM, BALDWIN JE, SCHOFIELD CJ. ChemInform Abstract: Reaction of (Trifluoromethyl)trimethylsilane with Oxazolidin-5-ones: Synthesis of Peptidic and Nonpeptidic Trifluoromethyl Ketones. Cheminform. 29: no-no. DOI: 10.1002/chin.199850080 |
0.405 |
|
| 2010 |
BALDWIN JE, SPRING DR, WHITEHEAD RC. ChemInform Abstract: A Novel Diels-Alder Approach to Hydroisoquinolines. Cheminform. 29: no-no. DOI: 10.1002/chin.199843163 |
0.426 |
|
| 2010 |
ROBINSON JK, LEE V, CLARIDGE TDW, BALDWIN JE, SCHOFIELD CJ. ChemInform Abstract: Synthesis of (2S,3R,4S), (2S,3S,4R)-Epoxyprolines and Aminohydroxyprolines. Cheminform. 29: no-no. DOI: 10.1002/chin.199821181 |
0.333 |
|
| 2010 |
ADLINGTON RM, BALDWIN JE, CATTERICK D, PRITCHARD GJ. ChemInform Abstract: A Versatile Approach to Pyrimidin-4-yl Substituted α-Amino Acids from Alkynyl Ketones; the Total Synthesis of L-Lathyrine. Cheminform. 29: no-no. DOI: 10.1002/chin.199803205 |
0.324 |
|
| 2010 |
ADLINGTON RM, BALDWIN JE, MCCOULL W, PRITCHARD GJ, SCHOFIELD CJ, WESTWOOD NJ. ChemInform Abstract: An Investigation of the N-Arylsulfonylation of 2-Azetidinones. Cheminform. 28: no-no. DOI: 10.1002/chin.199752129 |
0.573 |
|
| 2010 |
ADLINGTON RM, BALDWIN JE, CHEN B, COOPER SL, MCCOULL W, PRITCHARD GJ, HOWE TJ, BECKER GW, HERMANN RB, MCNULTY AM, NEUBAUER BL. ChemInform Abstract: Design and Synthesis of Novel Monocyclic β-Lactam Inhibitors of Prostate Specific Antigen. Cheminform. 28: no-no. DOI: 10.1002/chin.199746239 |
0.46 |
|
| 2010 |
WALTER MW, ADLINGTON RM, BALDWIN JE, SCHOFIELD CJ. ChemInform Abstract: Synthesis of Metallo-β-lactamase Inhibitors. Cheminform. 28: no-no. DOI: 10.1002/chin.199742231 |
0.404 |
|
| 2010 |
THIRKETTLE JE, BALDWIN JE, EDWARDS J, GRIFFIN JP, SCHOFIELD CJ. ChemInform Abstract: The Origin of the β-Lactam Carbons of Clavulanic Acid. Cheminform. 28: no-no. DOI: 10.1002/chin.199741293 |
0.384 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, BRYANS JS, LLOYD MD, SEWELL TJ, SCHOFIELD CJ, BAGGALEY KH, CASSELS R. ChemInform Abstract: Chemoenzymatic Synthesis of Bicyclic γ-Lactams Using Clavaminic Acid Synthase. Cheminform. 28: no-no. DOI: 10.1002/chin.199739289 |
0.472 |
|
| 2010 |
WALTER MW, FELICI A, GALLENI M, SOTO RP, ADLINGTON RM, BALDWIN JE, FRERE J, GOLOLOBOV M, SCHOFIELD CJ. ChemInform Abstract: Trifluoromethyl Alcohol and Ketone Inhibitors of Metallo-β- lactamases. Cheminform. 28: no-no. DOI: 10.1002/chin.199714159 |
0.541 |
|
| 2010 |
FEKNER T, BALDWIN JE, ADLINGTON RM, SCHOFIELD CJ. ChemInform Abstract: Syntheses of (6S,7S)- and (6S,7R)-Deacetoxycephalosporanic Acids from 6-Aminopenicillanic Acid. Cheminform. 27: no-no. DOI: 10.1002/chin.199648262 |
0.376 |
|
| 2010 |
FARTHING CN, BALDWIN JE, RUSSELL AT, SCHOFIELD CJ, SPIVEY AC. ChemInform Abstract: Syntheses of (S)-β-Pyrazolylalanine and (S)-Quisqualic Acid from a Serine-Derived Aziridine. Cheminform. 27: no-no. DOI: 10.1002/chin.199642222 |
0.612 |
|
| 2010 |
BALDWIN JE, FARTHING CN, RUSSELL AT, SCHOFIELD CJ, SPIVEY AC. ChemInform Abstract: Use of (S)-N-tert-Butoxycarbonylaziridine-2-carboxylate Derivatives for α-Amino Acid Synthesis. Cheminform. 27: no-no. DOI: 10.1002/chin.199639222 |
0.652 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, MARQUESS DG, PITT AR, PORTER MJ, RUSSELL AT. ChemInform Abstract: Evidence for an Insertion-Homolysis Mechanism for Carbon-Sulfur Bond Formation in Penicillin Biosynthesis. Part 2. Incubation and Interpretation. Cheminform. 27: no-no. DOI: 10.1002/chin.199625248 |
0.543 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, MARQUESS DG, PITT AR, PORTER MJ, RUSSELL AT. ChemInform Abstract: Evidence for an Insertion-Homolysis Mechanism for Carbon-Sulfur Bond Formation in Penicillin Biosynthesis. Part 1. Synthesis of Tripeptide Probes. Cheminform. 27: no-no. DOI: 10.1002/chin.199625247 |
0.571 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, ELEND AS, SMITH ML. ChemInform Abstract: Enantiospecific Synthesis of (3R,4R)-3-Amino-1-hydroxy-4-methyl- pyrrolidin-2-one (L-687,414), an NMDA Receptor Antagonist. Cheminform. 27: no-no. DOI: 10.1002/chin.199609122 |
0.472 |
|
| 2010 |
WALTER MW, ADLINGTON RM, BALDWIN JE, CHUHAN J, SCHOFIELD CJ. ChemInform Abstract: Reaction of Ruppert′s Reagent (TMS-CF3) with Oxazolidinones: Synthesis of Protected α-Amino Trifluoromethylketones. Cheminform. 27: no-no. DOI: 10.1002/chin.199605231 |
0.452 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, BEBBINGTON D, RUSSELL AT. ChemInform Abstract: Asymmetric Total Synthesis of the Individual Diastereoisomers of Hypoglycin A. Cheminform. 26: no-no. DOI: 10.1002/chin.199512276 |
0.504 |
|
| 2010 |
BALDWIN JE, MACKENZIE TURNER SC, MOLONEY MG. ChemInform Abstract: Enantioselective Synthesis of Novel Functionalized Prolines via (3 + 2) Cycloadditions of a Chiral Azomethine Ylid. Cheminform. 26: no-no. DOI: 10.1002/chin.199509185 |
0.525 |
|
| 2010 |
BALDWIN JE, MACKENZIE TURNER SC, MOLONEY MG. ChemInform Abstract: The Synthesis of Substituted Pyrrolidines by a Samarium(II) Iodide Mediated Ring Closure. Part 1. Cheminform. 25: no-no. DOI: 10.1002/chin.199452135 |
0.522 |
|
| 2010 |
LAWLOR EJ, ELSON SW, HOLLAND S, CASSELS R, HODGSON JE, LLOYD MD, BALDWIN JE, SCHOFIELD CJ. ChemInform Abstract: Expression in Escherichia coli of a Clavaminic Acid Synthase Isozyme: A Trifunctional Oxygenase Involved in Clavulanic Acid Biosynthesis. Cheminform. 25: no-no. DOI: 10.1002/chin.199449054 |
0.388 |
|
| 2010 |
BALDWIN JE, FIELD RA, LAWRENCE CC, LEE V, ROBINSON JK, SCHOFIELD CJ. ChemInform Abstract: Substrate Specificity of Proline 4-Hydroxylase: Chemical and Enzymatic Synthesis of (2S,3R,4S)-Epoxyproline. Cheminform. 25: no-no. DOI: 10.1002/chin.199447216 |
0.548 |
|
| 2010 |
ADLINGTON RM, BALDWIN JE, GANSAEUER A, MCCOULL W, RUSSELL AT. ChemInform Abstract: A Study of the Intramolecular Stille Cross Coupling Reaction of Vinylstannyl Chloroformates: Application to the Synthesis of α- Methylene Lactones. Cheminform. 25: no-no. DOI: 10.1002/chin.199446062 |
0.525 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, MELLOR LC. ChemInform Abstract: Synthesis of Chiral Isoxazolidin-5-ones and Their Applications to the Synthesis of β-Aminoalanines and β-(N-Hydroxyamino)alanines. Cheminform. 25: no-no. DOI: 10.1002/chin.199439240 |
0.521 |
|
| 2010 |
BALDWIN JE, FUJISHIMA Y, GOH K, SCHOFIELD CJ. ChemInform Abstract: Enzymes of Valclavam Biosynthesis Cheminform. 25: no-no. DOI: 10.1002/chin.199434264 |
0.359 |
|
| 2010 |
BALDWIN JE, GOH K, SCHOFIELD CJ. ChemInform Abstract: Biosynthetic Precursors of Valclavam (I). Cheminform. 25: no-no. DOI: 10.1002/chin.199434263 |
0.404 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, RUSSELL AT, SMITH ML. ChemInform Abstract: Synthesis of a Biologically Active Analogue of Antibiotic A-32390A. Cheminform. 25: no-no. DOI: 10.1002/chin.199418244 |
0.466 |
|
| 2010 |
BALDWIN JE, CLARIDGE TDW, GOH K, KEEPING JW, SCHOFIELD CJ. ChemInform Abstract: Revised Structures for Tue 1718B (Ia) and Valclavam (Ib). Cheminform. 25: no-no. DOI: 10.1002/chin.199401305 |
0.313 |
|
| 2010 |
BALDWIN JE, SPIVEY AC, SCHOFIELD CJ, SWEENEY JB. ChemInform Abstract: Amino Acid Synthesis via Ring Opening of N-Sulfonyl Aziridine-2- carboxylate Esters with Organometallic Reagents. Cheminform. 24: no-no. DOI: 10.1002/chin.199346123 |
0.659 |
|
| 2010 |
BALDWIN JE, HULME C, SCHOFIELD CJ, EDWARDS AJ. ChemInform Abstract: Synthesis of Potential β-Turn Bicyclic Dipeptide Mimetics. Cheminform. 24: no-no. DOI: 10.1002/chin.199336201 |
0.412 |
|
| 2010 |
BALDWIN JE, MOLONEY MG, PARSONS AF. ChemInform Abstract: Intramolecular Cobalt Cyclization for the Construction of Substituted Pyrrolidines. Cheminform. 24: no-no. DOI: 10.1002/chin.199308108 |
0.533 |
|
| 2010 |
BALDWIN JE, LYNCH GP, SCHOFIELD CJ. ChemInform Abstract: Isopenicillin N Synthase: A New Mode of Reactivity. Cheminform. 24: no-no. DOI: 10.1002/chin.199306060 |
0.356 |
|
| 2010 |
BALDWIN JE, HULME C, SCHOFIELD CJ. ChemInform Abstract: Syntheses of cis- and trans-Pyrrolidine-2,5-dicarboxylic Acids. Cheminform. 23: no-no. DOI: 10.1002/chin.199239275 |
0.381 |
|
| 2010 |
BALDWIN JE, LEE V, SCHOFIELD CJ. ChemInform Abstract: Synthesis of a Bicyclic γ-Lactam Dipeptide Analogue. Cheminform. 23: no-no. DOI: 10.1002/chin.199234157 |
0.467 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, CROUCH NP, SCHOFIELD CJ, TURNER NJ, APLIN RT. ChemInform Abstract: Cephalosporin Biosynthesis: A Branched Pathway Sensitive to an Isotope Effect. Cheminform. 23: no-no. DOI: 10.1002/chin.199211062 |
0.325 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, CROUCH NP, KEEPING JW, LEPPARD SW, PITLIK J, SCHOFIELD CJ, SOBEY WJ, WOOD ME. ChemInform Abstract: Studies on the Mechanism of Deacetoxy-Deacetylcephalosporin C Synthase Using Cyclopropyl Substituted Cephalosporin Probes. Cheminform. 23: no-no. DOI: 10.1002/chin.199210297 |
0.382 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, RAMCHARITAR SH. ChemInform Abstract: Intramolecular Palladium-Catalyzed Cross Coupling. A Route to γ- Oxo-α,β-Unsaturated Macrocycles. Cheminform. 23: no-no. DOI: 10.1002/chin.199209246 |
0.501 |
|
| 2010 |
BALDWIN JE, BRADLEY M, TURNER NJ, ADLINGTON RM, PITT AR, DEROME AE. ChemInform Abstract: Enzymic Conversion of Deuterated Analogues of δ-L-α- Aminoadipoyl-L-cysteinyl-D-allylglycine, an Unnatural Substrate for Isopenicillin N Synthase: A Unified Theory of Second Ring Closure Cheminform. 23: no-no. DOI: 10.1002/chin.199204258 |
0.545 |
|
| 2010 |
BALDWIN JE, BRADLEY M, TURNER NJ, ADLINGTON RM, PITT AR, SHERIDAN H. ChemInform Abstract: Synthesis of δ-L-α-Aminoadipoyl-L-cysteinyl-D-allylglycine (I), and Eight Deuterated Analogues, Substrates for the Investigation of the Mechanism of Action of Isopenicillin N Synthase. Cheminform. 23: no-no. DOI: 10.1002/chin.199204257 |
0.547 |
|
| 2010 |
BALDWIN JE, MOLONEY MG, SHIM SB. ChemInform Abstract: L-Pyroglutamic Acid as a Chiral Starting Material for Asymmetric Synthesis. Cheminform. 23: no-no. DOI: 10.1002/chin.199202210 |
0.55 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, GODFREY CRA, GOLLINS DW, SCHOFIELD CJ. ChemInform Abstract: The Stereospecific Synthesis of Alahopcin. Cheminform. 22: no-no. DOI: 10.1002/chin.199143234 |
0.447 |
|
| 2010 |
BALDWIN JE, JESUDASON CD, MOLONEY MG, MORGAN DR, PRATT AJ. ChemInform Abstract: The Synthesis of Substituted Aryl Diazirines. A Bifunctional Reagent Suitable for Application to Photoaffinity Labelling Studies. Cheminform. 22: no-no. DOI: 10.1002/chin.199142155 |
0.534 |
|
| 2010 |
BALDWIN JE, BRADLEY M, ABBOTT SD, ADLINGTON RM. ChemInform Abstract: New Penicillins from Isopenicillin N Synthase. Cheminform. 22: no-no. DOI: 10.1002/chin.199140254 |
0.475 |
|
| 2010 |
BALDWIN JE, ADLINGTON RM, BRYANS JS, BRINGHEN AO, COATES JB, CROUCH NP, LLOYD MD, SCHOFIELD CJ, ELSON SW, BAGGALEY KH, CASSELS R, NICHOLSON N. ChemInform Abstract: Isolation of Dihydroclavaminic Acid (I), an Intermediate in the Biosynthesis of Clavulanic Acid Cheminform. 22: no-no. DOI: 10.1002/chin.199135272 |
0.389 |
|
| 2010 |
BALDWIN JE, SPIVEY AC, SCHOFIELD CJ. ChemInform Abstract: Cyclic Sulfamidates: New Synthetic Precursors for β- Functionalized α-Amino Acids. Cheminform. 22: no-no. DOI: 10.1002/chin.199116260 |
0.618 |
|
| 2010 |
BALDWIN JE, BRADLEY M, ADLINGTON RM, NORRIS WJ, TURNER NJ. ChemInform Abstract: Further Evidence for the Involvement of a Monocyclic β-Lactam in the Enzymatic Conversion of δ-L-α-Aminoadipoyl-L-cysteinyl- D-valine into Isopenicillin N. Cheminform. 22: no-no. DOI: 10.1002/chin.199116259 |
0.525 |
|
| 2010 |
BALDWIN JE, MOLONEY MG, PARSONS AF. ChemInform Abstract: Enantioselective Synthesis of Kainoid Analogues by Cobalt-Mediated Cyclizations. Cheminform. 22: no-no. DOI: 10.1002/chin.199112312 |
0.559 |
|
| 2010 |
BALDWIN JE, LOWE C, SCHOFIELD CJ. ChemInform Abstract: The Synthesis of Potential γ-Lactam Antibiotics Containing a Cycloserine Nucleus. Cheminform. 22: no-no. DOI: 10.1002/chin.199111164 |
0.403 |
|
| 2010 |
BALDWIN JE, BRADLEY M, ABBOTT SD, ADLINGTON RM. ChemInform Abstract: Formation of Novel Unsaturated Side Chain Penicillins with Isopenicillin N Synthase. Cheminform. 22: no-no. DOI: 10.1002/chin.199104090 |
0.491 |
|
| 2010 |
BALDWIN JE, MOLONEY MG, PARSONS AF. ChemInform Abstract: Enantioselective Kainoid Synthesis by Cobalt-Mediated Cyclisation of an Amino Acid Derivative. Cheminform. 22: no-no. DOI: 10.1002/chin.199103311 |
0.556 |
|
| 2010 |
BALDWIN JE, MCCONNAUGHIE AW, MOLONEY MG, PRATT AJ, SHIM SB. ChemInform Abstract: New Photolabile Phosphate Protecting Groups. Cheminform. 22: no-no. DOI: 10.1002/chin.199101138 |
0.445 |
|
| 2009 |
Ge W, Clifton IJ, Howard-Jones AR, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Structural studies on the reaction of isopenicillin N synthase with a sterically demanding depsipeptide substrate analogue Chembiochem. 10: 2025-2031. PMID 19598184 DOI: 10.1002/Cbic.200900080 |
0.808 |
|
| 2008 |
Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Isopenicillin N synthase mediates thiolate oxidation to sulfenate in a depsipeptide substrate analogue: Implications for oxygen binding and a link to nitrile hydratase? Journal of the American Chemical Society. 130: 10096-10102. PMID 18620394 DOI: 10.1021/Ja8005397 |
0.795 |
|
| 2008 |
Eade SJ, Walter MW, Byrne C, Odell B, Rodriguez R, Baldwin JE, Adlington RM, Moses JE. Biomimetic synthesis of pyrone-derived natural products: exploring chemical pathways from a unique polyketide precursor. The Journal of Organic Chemistry. 73: 4830-9. PMID 18517253 DOI: 10.1021/Jo800220W |
0.676 |
|
| 2007 |
Stewart AC, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. A cyclobutanone analogue mimics penicillin in binding to isopenicillin N synthase Chembiochem. 8: 2003-2007. PMID 17907118 DOI: 10.1002/Cbic.200700176 |
0.785 |
|
| 2007 |
Howard-Jones AR, Elkins JM, Clifton IJ, Roach PL, Adlington RM, Baldwin JE, Rutledge PJ. Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight Biochemistry. 46: 4755-4762. PMID 17397141 DOI: 10.1021/Bi062314Q |
0.82 |
|
| 2007 |
Baldwin JE, Pritchard GJ, Rathmell RE. Synthesis of Novel Unsymmetrical and Symmetrical Diacetylenic Ketones Synthetic Communications. 30: 3833-3847. DOI: 10.1080/00397910008086940 |
0.343 |
|
| 2007 |
Fenlon TW, Schwaebisch D, Mayweg AVW, Lee V, Adlington RM, Baldwin JE. Studies towards the synthesis of lindenene: Unexpected stereochemical outcome of an intramolecular cyclopropanation reaction and synthesis of (±)-epi-lindenene and (±)-iso-lindenene Synlett. 2679-2682. DOI: 10.1055/S-2007-991069 |
0.53 |
|
| 2007 |
Chen R, Lee V, Adlington RM, Baldwin JE. A facile synthesis of ethyl 2-acetamido-4-methylenehex-5-enoate, a versatile Diels-Alder synthon for the parallel synthesis of novel α-amino acid derivatives Synthesis. 113-117. DOI: 10.1055/S-2006-958929 |
0.618 |
|
| 2007 |
Shorey BJ, Lee V, Baldwin JE. Synthesis of the Arctic sponge alkaloid viscosaline and the marine sponge alkaloid theonelladin C Tetrahedron. 63: 5587-5592. DOI: 10.1016/J.Tet.2007.04.020 |
0.385 |
|
| 2007 |
Rodriguez R, Adlington RM, Eade SJ, Walter MW, Baldwin JE, Moses JE. Total synthesis of cyercene A and the biomimetic synthesis of (±)-9,10-deoxytridachione and (±)-ocellapyrone A Tetrahedron. 63: 4500-4509. DOI: 10.1016/J.Tet.2007.03.057 |
0.695 |
|
| 2007 |
Rodriguez R, Adlington RM, Eade SJ, Walter MW, Baldwin JE, Moses JE. Total Synthesis of Cyercene A (I) and the Biomimetic Synthesis of (.+-.)-9,10-Deoxytridachione (II) and (.+-.)-Ocellapyrone A. Cheminform. 38. DOI: 10.1002/chin.200735216 |
0.581 |
|
| 2006 |
Kirkham JED, Lee V, Baldwin JE. Stereochemical reassignment of Mehta and Kundu's spiculoic acid A analogue Organic Letters. 8: 5537-5540. PMID 17107066 DOI: 10.1021/Ol062361A |
0.351 |
|
| 2006 |
Kirkham JED, Lee V, Baldwin JE. Biomimetic synthesis of marine sponge metabolite spiculoic acid A and establishment of the absolute configuration of the natural product Chemical Communications. 2863-2865. PMID 17007398 DOI: 10.1039/B607035C |
0.397 |
|
| 2006 |
Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. Unexpected oxidation of a depsipeptide substrate analogue in crystalline isopenicillin N synthase Chembiochem. 7: 351-358. PMID 16444759 DOI: 10.1002/Cbic.200500282 |
0.808 |
|
| 2006 |
Goundry WRF, Lee V, Baldwin JE. Synthesis of excitatory amino acid analogues Synlett. 2407-2410. DOI: 10.1055/S-2006-950399 |
0.3 |
|
| 2006 |
Lawrence AL, Wegner HA, Jacobsen MF, Adlington RM, Baldwin JE. Investigations towards the synthesis of (-)-coprinolone, via a thermal 8π-6π electrocyclization cascade of 1,5,7-trien-4-ones Tetrahedron Letters. 47: 8717-8720. DOI: 10.1016/J.Tetlet.2006.10.021 |
0.679 |
|
| 2006 |
Smith CD, Tchabanenko K, Adlington RM, Baldwin JE. Synthesis of linked heterocycles via use of bis-acetylenic compounds Tetrahedron Letters. 47: 3209-3212. DOI: 10.1016/J.Tetlet.2006.03.052 |
0.567 |
|
| 2006 |
Tchabanenko K, Taylor MGO, Adlington RM, Baldwin JE. Synthesis of substituted pyrano[3,2-c]pyridines via Diels-Alder reaction of 3-methylenepyridin-4-one Tetrahedron Letters. 47: 39-41. DOI: 10.1016/J.Tetlet.2005.10.119 |
0.591 |
|
| 2006 |
Comméiras L, Moses JE, Adlington RM, Baldwin JE, Cowley AR, Baker CM, Albrecht B, Grant GH. Total synthesis of the epoxyquinol dimer (+)-panepophenanthrin: application of a diastereospecific biomimetic Diels-Alder dimerisation Tetrahedron. 62: 9892-9901. DOI: 10.1016/J.Tet.2006.08.010 |
0.71 |
|
| 2006 |
Irlapati NR, Baldwin JE, Adlington RM, Pritchard GJ, Cowley AR. Studies towards the biomimetic synthesis of pyridomacrolidin Tetrahedron. 62: 4603-4614. DOI: 10.1016/J.Tet.2006.01.090 |
0.588 |
|
| 2006 |
Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. The biomimetic synthesis of SNF4435C and SNF4435D, and the total synthesis of the polyene metabolites aureothin, N-acetyl-aureothamine and spectinabilin Tetrahedron. 62: 1675-1689. DOI: 10.1016/J.Tet.2005.11.058 |
0.688 |
|
| 2006 |
He J, Tchabanenko K, Adlington RM, Cowley AR, Baldwin JE. New domino silyl enol ether reactions in the synthesis of a tetrodecamycin fragment European Journal of Organic Chemistry. 4003-4013. DOI: 10.1002/Ejoc.200600346 |
0.598 |
|
| 2006 |
Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. The Biomimetic Synthesis of SNF4435C (I) and SNF4435D (II), and the Total Synthesis of the Polyene Metabolites Aureothin (IIIa), N-Acetyl-aureothamine (IIIb) and Spectinabilin (IV). Cheminform. 37. DOI: 10.1002/chin.200625206 |
0.595 |
|
| 2005 |
Rodriguez R, Moses JE, Adlington RM, Baldwin JE. A new and efficient method for o-quinone methide intermediate generation: application to the biomimetic synthesis of the benzopyran derived natural products (+/-)-lucidene and (+/-)-alboatrin. Organic & Biomolecular Chemistry. 3: 3488-95. PMID 16172685 DOI: 10.1039/B508972G |
0.698 |
|
| 2005 |
Howard-Jones AR, Rutledge PJ, Clifton IJ, Adlington RM, Baldwin JE. Unique binding of a non-natural L,L,L-substrate by isopenicillin N synthase Biochemical and Biophysical Research Communications. 336: 702-708. PMID 16143309 DOI: 10.1016/J.Bbrc.2005.08.155 |
0.783 |
|
| 2005 |
Eade SJ, Adlington RM, Cowley AR, Walter MW, Baldwin JE. A novel oxidative rearrangement of 6-methoxypyran-2-ones. Organic Letters. 7: 3705-7. PMID 16092855 DOI: 10.1021/Ol0513490 |
0.563 |
|
| 2005 |
Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. The total synthesis of spectinabilin and its biomimetic conversion to SNF4435C and SNF4435D. Organic Letters. 7: 2473-6. PMID 15932226 DOI: 10.1021/Ol0507874 |
0.685 |
|
| 2005 |
Long AJ, Clifton IJ, Roach PL, Baldwin JE, Rutledge PJ, Schofield CJ. Structural studies on the reaction of isopenicillin N synthase with the truncated substrate analogues delta-(L-alpha-aminoadipoyl)-L-cysteinyl-glycine and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alanine. Biochemistry. 44: 6619-28. PMID 15850395 DOI: 10.1021/Bi047478Q |
0.77 |
|
| 2005 |
Adamo MFA, Baldwin JE, Adlington RM. Application of bis-acetylenic ketones in synthesis: One-pot preparation of the 1,2,4-triazepine and oxatriazaindenone cores Journal of Organic Chemistry. 70: 3307-3308. PMID 15823002 DOI: 10.1021/Jo047991+ |
0.565 |
|
| 2005 |
Moses JE, Adlington RM, Rodriguez R, Eade SJ, Baldwin JE. Biomimetic synthesis of (+/-)-9,10-deoxytridachione. Chemical Communications (Cambridge, England). 1687-9. PMID 15791299 DOI: 10.1039/B418988D |
0.699 |
|
| 2005 |
Mee SP, Lee V, Baldwin JE. Significant enhancement of the Stille reaction with a new combination of reagents-copper(I) iodide with cesium fluoride. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 3294-308. PMID 15786503 DOI: 10.1002/Chem.200401162 |
0.32 |
|
| 2005 |
Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. A short total synthesis of aureothin and N-acetylaureothamine. Organic Letters. 7: 641-4. PMID 15704914 DOI: 10.1021/Ol047594L |
0.714 |
|
| 2005 |
Tchabanenko K, Adlington RM, Cowley AR, Baldwin JE. Biomimetic total synthesis of (+)-himbacine Organic Letters. 7: 585-588. PMID 15704900 DOI: 10.1021/Ol047676+ |
0.592 |
|
| 2005 |
Eade SJ, Adlington RM, Cowley AR, Walter MW, Baldwin JE. A novel oxidative rearrangement of 6-methoxypyran-2-ones Organic Letters. 7: 3705-3707. DOI: 10.1021/ol0513490 |
0.422 |
|
| 2005 |
Bagal SK, Adlington RM, Brown RAB, Baldwin JE. Regioselectivity of dimerisation of butenolides via captodative stabilised radicaloid intermediates Tetrahedron Letters. 46: 4633-4637. DOI: 10.1016/J.Tetlet.2005.04.125 |
0.517 |
|
| 2005 |
Tchabanenko K, Chesworth R, Parker JS, Anand NK, Russell AT, Adlington RM, Baldwin JE. Biomimetic approach to Galbulimina type I alkaloids Tetrahedron. 61: 11649-11656. DOI: 10.1016/J.Tet.2005.09.050 |
0.528 |
|
| 2005 |
Kirkham JED, Courtney TDL, Lee V, Baldwin JE. Asymmetric synthesis of cytotoxic sponge metabolites R-strongylodiols A and B and an analogue Tetrahedron. 61: 7219-7232. DOI: 10.1016/J.Tet.2005.05.034 |
0.301 |
|
| 2005 |
Celanire S, Marlin F, Baldwin JE, Adlington RM. Base-assisted intramolecular 6-acetoxypyranone-acetylene [5+2] cycloaddition. Synthesis and reactivity of novel oxa-tricyclo[5.3.1.0 1,5]undecenones Tetrahedron. 61: 3025-3032. DOI: 10.1016/J.Tet.2005.01.113 |
0.58 |
|
| 2005 |
Baldwin JE, Adlington RM, Sham VWW, Marquez R, Bulger PG. Biomimetic synthesis of (±)-aculeatin D Tetrahedron. 61: 2353-2363. DOI: 10.1016/J.Tet.2005.01.021 |
0.578 |
|
| 2005 |
Irlapati NR, Baldwin JE, Adlington RM, Pritchard GJ, Cowley AR. Regio- and stereospecific [3+2] cycloaddition of an unusual nitrone derived from a N-hydroxy-2-pyridone with medium ring enones Tetrahedron. 61: 1773-1784. DOI: 10.1016/J.Tet.2004.12.019 |
0.561 |
|
| 2005 |
Romeril SP, Lee V, Baldwin JE, Claridge TDW. On the synthesis of pyrinodemin A. Part 1: The location of the olefin Tetrahedron. 61: 1127-1140. DOI: 10.1016/J.Tet.2004.11.051 |
0.344 |
|
| 2005 |
Krall JA, Rutledge PJ, Baldwin JE. Design and synthesis of an isopenicillin N synthase mimic Tetrahedron. 61: 137-143. DOI: 10.1016/J.Tet.2004.10.041 |
0.699 |
|
| 2005 |
Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. The Total Synthesis of Spectinabilin (I) and Its Biomimetic Conversion to SNF4435C (II) and SNF4435D (III). Cheminform. 36. DOI: 10.1002/chin.200544226 |
0.649 |
|
| 2005 |
Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. A Short Total Synthesis of Aureothin (Ia) and N-Acetylaureothamine (Ib). Cheminform. 36. DOI: 10.1002/chin.200528208 |
0.579 |
|
| 2004 |
Bagal SK, Adlington RM, Baldwin JE, Marquez R. Dimerization of butenolide structures. A biomimetic approach to the dimeric sesquiterpene lactones (±)-biatractylolide and (±)- biepiasterolide Journal of Organic Chemistry. 69: 9100-9108. PMID 15609943 DOI: 10.1021/Jo0488053 |
0.452 |
|
| 2004 |
Schwaebisch D, Tchabanenko K, Adlington RM, Cowley AM, Baldwin JE. Biomimetic synthesis of the pyrrolobenzoxazine core of paeciloxazine. Chemical Communications (Cambridge, England). 2552-3. PMID 15543275 DOI: 10.1039/B412300J |
0.574 |
|
| 2004 |
Rodriguez R, Adlington RM, Moses JE, Cowley A, Baldwin JE. A new and efficient method for o-quinone methide intermediate generation: application to the biomimetic synthesis of (+/-)-Alboatrin. Organic Letters. 6: 3617-9. PMID 15387562 DOI: 10.1021/Ol048479D |
0.679 |
|
| 2004 |
Grummitt AR, Rutledge PJ, Clifton IJ, Baldwin JE. Active-site-mediated elimination of hydrogen fluoride from a fluorinated substrate analogue by isopenicillin N synthase. The Biochemical Journal. 382: 659-66. PMID 15175003 DOI: 10.1042/Bj20040529 |
0.769 |
|
| 2004 |
Lloyd MD, Lipscomb SJ, Hewitson KS, Hensgens CM, Baldwin JE, Schofield CJ. Controlling the substrate selectivity of deacetoxycephalosporin/deacetylcephalosporin C synthase. The Journal of Biological Chemistry. 279: 15420-6. PMID 14734549 DOI: 10.1074/Jbc.M313928200 |
0.436 |
|
| 2004 |
Schwaebisch D, Tchabanenko K, Adlington RM, Cowley AM, Baldwin JE. Biomimetic synthesis of the pyrrolobenzoxazine core of paeciloxazine Chemical Communications. 10: 2552-2553. DOI: 10.1039/b412300j |
0.499 |
|
| 2004 |
Kyei AS, Tchabanenko K, Baldwin JE, Adlington RM. Radical dearomatising spirocyclisations onto the C-2 position of benzofuran and indole Tetrahedron Letters. 45: 8931-8934. DOI: 10.1016/J.Tetlet.2004.09.148 |
0.535 |
|
| 2004 |
Moses JE, Baldwin JE, Adlington RM. An efficient synthesis of cyercene A Tetrahedron Letters. 45: 6447-6448. DOI: 10.1016/J.Tetlet.2004.06.125 |
0.696 |
|
| 2004 |
Kirkham JE, Courtney TD, Lee V, Baldwin JE. Asymmetric synthesis of cytotoxic sponge metabolites R -strongylodiols A and B Tetrahedron Letters. 45: 5645-5647. DOI: 10.1016/J.Tetlet.2004.05.122 |
0.329 |
|
| 2004 |
Irlapati NR, Adlington RM, Conte A, Pritchard GJ, Marquez R, Baldwin JE. Total synthesis of pyridovericin Tetrahedron. 60: 9307-9317. DOI: 10.1016/J.Tet.2004.07.035 |
0.58 |
|
| 2004 |
Mee SPH, Lee V, Baldwin JE, Cowley A. Total synthesis of 5,5′,6,6′-tetrahydroxy-3,3′-biindolyl, the proposed structure of a potent antioxidant found in beetroot (Beta vulgaris) Tetrahedron. 60: 3695-3712. DOI: 10.1016/J.Tet.2004.02.043 |
0.307 |
|
| 2004 |
Brückner S, Baldwin JE, Adlington RM, Claridge TDW, Odell B. Thermal and palladium catalyzed pericyclic rearrangements of a pentaene ester Tetrahedron. 60: 2785-2788. DOI: 10.1016/J.Tet.2004.01.078 |
0.543 |
|
| 2004 |
Adamo MFA, Adlington RM, Baldwin JE, Day AL. A parallel synthesis approach towards a family of C-nucleosides Tetrahedron. 60: 841-849. DOI: 10.1016/J.Tet.2003.11.055 |
0.537 |
|
| 2004 |
Commeiras L, Woodcock SC, Baldwin JE, Adlington RM, Cowley AR, Wilkinson PJ. New access to the 1H-pyrazolo[4,3-c]pyridine core from bis-acetylenic-N- benzoylhydrazones Tetrahedron. 60: 933-938. DOI: 10.1016/J.Tet.2003.11.036 |
0.528 |
|
| 2003 |
Moses JE, Baldwin JE, Brückner S, Eade SJ, Adlington RM. Biomimetic studies on polyenes. Organic & Biomolecular Chemistry. 1: 3670-84. PMID 14649898 DOI: 10.1039/B306933H |
0.706 |
|
| 2003 |
Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue. Organic & Biomolecular Chemistry. 1: 1455-60. PMID 12926272 DOI: 10.1039/B212270G |
0.818 |
|
| 2003 |
Bagal SK, Adlington RM, Baldwin JE, Marquez R, Cowley A. Biomimetic synthesis of biatractylolide and biepiasterolide Organic Letters. 5: 3049-3052. PMID 12916978 DOI: 10.1021/Ol035022F |
0.53 |
|
| 2003 |
Moses JE, Commeiras L, Baldwin JE, Adlington RM. Total synthesis of panepophenanthrin. Organic Letters. 5: 2987-8. PMID 12916962 DOI: 10.1021/Ol0349817 |
0.71 |
|
| 2003 |
Irlapati NR, Baldwin JE, Adlington RM, Pritchard GJ, Cowley A. An unusual oxidative cyclization: Studies towards the biomimetic synthesis of pyridomacrolidin Organic Letters. 5: 2351-2354. PMID 12816446 DOI: 10.1021/Ol034736N |
0.518 |
|
| 2003 |
Long AJ, Clifton IJ, Roach PL, Baldwin JE, Schofield CJ, Rutledge PJ. Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate. The Biochemical Journal. 372: 687-93. PMID 12622704 DOI: 10.1042/Bj20021627 |
0.792 |
|
| 2003 |
Moses JE, Baldwin JE, Marquez R, Adlington RM, Claridge TD, Odell B. Biomimetic synthesis of the crispatene core. Organic Letters. 5: 661-3. PMID 12605484 DOI: 10.1021/Ol020242Z |
0.67 |
|
| 2003 |
Baldwin JE, Adlington RM, Wilkinson PJ, Marquez R, Adamo MFA. Studies towards the biomimetic synthesis of ginsenoyne L; efficient synthesis of 2′-epi-ginsenoyne L Heterocycles. 59: 81-85. DOI: 10.3987/Com-02-S25 |
0.597 |
|
| 2003 |
Mee SPH, Lee V, Baldwin JE. An efficient synthesis of 3,4-bis(tri-n-butylstannyl)furan Synthetic Communications. 33: 3205-3209. DOI: 10.1081/Scc-120023442 |
0.358 |
|
| 2003 |
Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue Organic and Biomolecular Chemistry. 1: 1455-1460. DOI: 10.1039/b212270g |
0.798 |
|
| 2003 |
Moses JE, Baldwin JE, Adlington RM, Cowley AR, Marquez R. Thermally induced cascade pericyclic reaction pathways from tetraene esters Tetrahedron Letters. 44: 6625-6627. DOI: 10.1016/S0040-4039(03)01673-3 |
0.676 |
|
| 2003 |
Bagal SK, Adlington RM, Marquez R, Cowley AR, Baldwin JE. Studies towards the biomimetic synthesis of bisesquiterpene lactones Tetrahedron Letters. 44: 4993-4996. DOI: 10.1016/S0040-4039(03)01172-9 |
0.568 |
|
| 2003 |
Baldwin JE, Mayweg AVW, Pritchard GJ, Adlington RM. Expedient synthesis of a highly substituted tropolone via a 3-oxidopyrylium [5+2] cycloaddition reaction Tetrahedron Letters. 44: 4543-4545. DOI: 10.1016/S0040-4039(03)00987-0 |
0.609 |
|
| 2003 |
Adamo MFA, Adlington RM, Baldwin JE, Pritchard GJ, Rathmell RE. Practical routes to diacetylenic ketones and their application for the preparation of alkynyl substituted pyridines, pyrimidines and pyrazoles Tetrahedron. 59: 2197-2205. DOI: 10.1016/S0040-4020(03)00244-8 |
0.574 |
|
| 2003 |
Goundry WRF, Baldwin JE, Lee V. Total synthesis of cytotoxic sponge alkaloids hachijodines F and G Tetrahedron. 59: 1719-1729. DOI: 10.1016/S0040-4020(03)00115-7 |
0.302 |
|
| 2003 |
Romeril SP, Lee V, Baldwin JE, Claridge TDW, Odell B. Investigation into the absolute stereochemistry of the marine sponge alkaloid pyrinodemin A Tetrahedron Letters. 44: 7757-7761. DOI: 10.1016/J.Tetlet.2003.08.097 |
0.308 |
|
| 2003 |
Brückner S, Baldwin JE, Moses J, Adlington RM, Cowley AR. Mechanistic evidence supporting the biosynthesis of photodeoxytridachione Tetrahedron Letters. 44: 7471-7473. DOI: 10.1016/J.Tetlet.2003.08.021 |
0.709 |
|
| 2003 |
Ferguson AC, Adlington RM, Martyres DH, Rutledge PJ, Cowley A, Baldwin JE. Total synthesis of a novel 2-thiabicyclo[3.2.0]heptan-6-one analogue of penicillin N Tetrahedron. 59: 8233-8243. DOI: 10.1016/J.Tet.2003.08.004 |
0.715 |
|
| 2002 |
Gygi CM, Leibovitch IY, Adlington R, Baldwin JE, Chen B, Mccoull W, Pritchard GJ, Becker GW, Dixon EP, Little SP, Sutkowski DM, Teater C, Neubauer BL. Prostate-specific antigen (PSA)-mediated proliferation, androgenic regulation and inhibitory effects of LY312340 in HOS-TE85 (TE85) human osteosarcoma cells. Anticancer Research. 22: 2725-32. PMID 12529988 |
0.403 |
|
| 2002 |
Rutledge PJ, Burzlaff NI, Elkins JM, Pickford M, Baldwin JE, Roach PL. A device for the high-pressure oxygenation of protein crystals. Analytical Biochemistry. 308: 265-8. PMID 12419338 DOI: 10.1016/S0003-2697(02)00246-4 |
0.778 |
|
| 2002 |
Moses JE, Baldwin JE, Marquez R, Adlington RM, Cowley AR. Studies on the biomimetic synthesis of SNF4435 C and D. Organic Letters. 4: 3731-4. PMID 12375930 DOI: 10.1021/Ol020157R |
0.721 |
|
| 2002 |
Adlington RM, Baldwin JE, Mayweg AVW, Pritchard GJ. Biomimetic cycloaddition approach to tropolone natural products via a tropolone ortho-quinone methide Organic Letters. 4: 3009-3011. PMID 12182611 DOI: 10.1021/Ol026467R |
0.51 |
|
| 2002 |
Baldwin JE, Adlington RM, Conte A, Irlapati NR, Marquez R, Pritchard GJ. Total synthesis of pyridovericin: Studies toward the biomimetic synthesis of pyridomacrolidin Organic Letters. 4: 2125-2127. PMID 12074648 DOI: 10.1021/Ol0200504 |
0.597 |
|
| 2002 |
Lipscomb SJ, Lee HJ, Mukherji M, Baldwin JE, Schofield CJ, Lloyd MD. The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase. European Journal of Biochemistry / Febs. 269: 2735-9. PMID 12047382 DOI: 10.1046/J.1432-1033.2002.02945.X |
0.384 |
|
| 2002 |
Elkins JM, Ryle MJ, Clifton IJ, Dunning Hotopp JC, Lloyd JS, Burzlaff NI, Baldwin JE, Hausinger RP, Roach PL. X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates. Biochemistry. 41: 5185-92. PMID 11955067 DOI: 10.1021/Bi016014E |
0.792 |
|
| 2002 |
Adlington RM, Baldwin JE, Cox RJ, Pritchard GJ. A rapid entry to natural and unnatural disubstituted maleic anhydrides Synlett. 820-822. DOI: 10.1055/S-2002-25344 |
0.534 |
|
| 2002 |
Romeril SP, Lee V, Claridge TDW, Baldwin JE. Synthesis of a possible structure of pyrinodemin A Tetrahedron Letters. 43: 327-329. DOI: 10.1016/S0040-4039(01)02117-7 |
0.318 |
|
| 2002 |
Baldwin JE, Bulger PG, Marquez R. Fast and efficient synthesis of novel fumagillin analogues Tetrahedron. 58: 5441-5452. DOI: 10.1016/S0040-4020(02)00514-8 |
0.373 |
|
| 2001 |
Ogle JM, Clifton IJ, Rutledge PJ, Elkins JM, Burzlaff NI, Adlington RM, Roach PL, Baldwin JE. Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction. Chemistry & Biology. 8: 1231-7. PMID 11755401 DOI: 10.1016/S1074-5521(01)00090-4 |
0.82 |
|
| 2001 |
Clifton IJ, Hsueh LC, Baldwin JE, Harlos K, Schofield CJ. Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases. European Journal of Biochemistry / Febs. 268: 6625-36. PMID 11737217 DOI: 10.1046/J.0014-2956.2001.02617.X |
0.631 |
|
| 2001 |
Hamilton CS, Yasuhara A, Baldwin JE, Lloyd MD, Rutledge PJ. Contrasting fates for 6-α-methylpenicillin N upon oxidation by deacetoxycephalosporin C synthase (DAOCS) and deacetoxy/deacetylcephalosporin C synthase (DAOC/DACS) Bioorganic and Medicinal Chemistry Letters. 11: 2511-2514. PMID 11549458 DOI: 10.1016/S0960-894X(01)00470-X |
0.622 |
|
| 2001 |
Dubus A, Lloyd MD, Lee HJ, Schofield CJ, Baldwin JE, Frere JM. Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase. Cellular and Molecular Life Sciences : Cmls. 58: 835-43. PMID 11437242 DOI: 10.1007/Pl00000904 |
0.429 |
|
| 2001 |
Lee HJ, Lloyd MD, Harlos K, Clifton IJ, Baldwin JE, Schofield CJ. Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS). Journal of Molecular Biology. 308: 937-48. PMID 11352583 DOI: 10.1006/Jmbi.2001.4649 |
0.629 |
|
| 2001 |
Baldwin JE, Romeril SP, Lee V, Claridge TD. Studies toward the total synthesis of the cytotoxic sponge alkaloid pyrinodemin A. Organic Letters. 3: 1145-8. PMID 11348180 DOI: 10.1021/Ol015646Q |
0.346 |
|
| 2001 |
Adlington RM, Baldwin JE, Becker GW, Chen B, Cheng L, Cooper SL, Hermann RB, Howe TJ, McCoull W, McNulty AM, Neubauer BL, Pritchard GJ. Design, synthesis, and proposed active site binding analysis of monocyclic 2-azetidinone inhibitors of prostate specific antigen. Journal of Medicinal Chemistry. 44: 1491-508. PMID 11334560 DOI: 10.1021/Jm000145G |
0.446 |
|
| 2001 |
Baldwin JE, Fryer AM, Pritchard GJ. Parallel synthesis of novel heteroaromatic acromelic acid analogues from kainic acid. The Journal of Organic Chemistry. 66: 2588-96. PMID 11304175 DOI: 10.1021/Jo000846L |
0.396 |
|
| 2001 |
Lee HJ, Lloyd MD, Clifton IJ, Harlos K, Dubus A, Baldwin JE, Frere JM, Schofield CJ. Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258. The Journal of Biological Chemistry. 276: 18290-5. PMID 11279000 DOI: 10.1074/Jbc.M100085200 |
0.632 |
|
| 2001 |
Baldwin JE, Pritchard GJ, Rathmell RE. The reactions of diacetylenic ketones with nitrogen nucleophiles; facile preparation of alkynyl substituted pyrimidines and pyrazoles Journal of the Chemical Society. Perkin Transactions 1. 2906-2908. DOI: 10.1039/B108645F |
0.393 |
|
| 2001 |
Adlington RM, Baldwin JE, Catterick D, Pritchard GJ. The efficient, enantioselective synthesis of quinoxaline, pyrazine and 1,2,4-triazine substituted α-amino acids from vicinal tricarbonyls Journal of the Chemical Society. Perkin Transactions 1. 668-679. DOI: 10.1039/B010134F |
0.599 |
|
| 2001 |
Baldwin JE, Adlington RM, Roussi F, Bulger PG, Marquez R, Mayweg AVW. Studies towards the biomimetic synthesis of the nonadrides CP-225,917 and CP-263,114 Tetrahedron. 57: 7409-7416. DOI: 10.1016/S0040-4020(01)00706-2 |
0.55 |
|
| 2001 |
Martyres DH, Baldwin JE, Adlington RM, Lee V, Probert MR, Watkin DJ. Synthesis of a novel thiabicyclo[3.2.0]heptan-6-one analogue of penicillin Tetrahedron. 57: 4999-5007. DOI: 10.1016/S0040-4020(01)00430-6 |
0.607 |
|
| 2000 |
Dubus A, Sami M, Brown TJ, Schofield CJ, Baldwin JE, Frère JM. Studies of isopenicillin N synthase enzymatic properties using a continuous spectrophotometric assay. Febs Letters. 485: 142-6. PMID 11094156 DOI: 10.1016/S0014-5793(00)02221-3 |
0.443 |
|
| 2000 |
Baldwin JE, Pritchard GJ, Williamson DS. The synthesis of 4-arylsulfanyl-substituted kainoid analogues from trans-4-hydroxy-L-proline. Bioorganic & Medicinal Chemistry Letters. 10: 1927-9. PMID 10987419 DOI: 10.1016/S0960-894X(00)00352-8 |
0.427 |
|
| 2000 |
Baldwin JE, Fryer AM, Pritchard GJ. Novel C-4 heteroaromatic kainoid analogues: a parallel synthesis approach. Bioorganic & Medicinal Chemistry Letters. 10: 309-11. PMID 10698461 DOI: 10.1016/S0960-894X(99)00690-3 |
0.373 |
|
| 2000 |
Zhang Z, Ren J, Stammers DK, Baldwin JE, Harlos K, Schofield CJ. Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase. Nature Structural Biology. 7: 127-33. PMID 10655615 DOI: 10.1038/72398 |
0.423 |
|
| 2000 |
Walter MW, Thaker N, Baldwin JE, Muller M, Schofield CJ. The reaction of TMS-CF3 with amino acid derived ring-templates: Studies with oxazin-2-ones and oxazolidin-5-ones Journal of Chemical Research - Part S. 310-311. DOI: 10.3184/030823400103167606 |
0.434 |
|
| 2000 |
Adlington RM, Baldwin JE, Catterick D, Pritchard GJ, Tang LT. The synthesis of novel heterocyclic substituted α-amino acids; further exploitation of α-amino acid alkynyl ketones as reactive substrates Journal of the Chemical Society, Perkin Transactions 1. 2311-2316. DOI: 10.1039/B001825M |
0.608 |
|
| 2000 |
Adlington RM, Baldwin JE, Catterick D, Pritchard GJ. A versatile synthetic route to quinoxaline, pyrazine and 1,2,4-triazine substituted α-amino acids from vicinal tricarbonyls Journal of the Chemical Society, Perkin Transactions 1. 299-302. DOI: 10.1039/A909722H |
0.587 |
|
| 2000 |
Adlington RM, Baldwin JE, Catterick D, Pritchard GJ, Tang LT. The synthesis of novel heterocyclic substituted α-amino acids; further exploitation of α-amino acid alkynyl ketones Journal of the Chemical Society-Perkin Transactions 1. 303-305. DOI: 10.1039/A909720A |
0.364 |
|
| 2000 |
Baldwin JE, James DA, Lee V. Preparation of 3-alkylpyridines. Formal total synthesis of haliclamines A and B Tetrahedron Letters. 41: 733-736. DOI: 10.1016/S0040-4039(99)02120-6 |
0.329 |
|
| 2000 |
Adlington RM, Baldwin JE, Pritchard GJ, Spencer KC. Synthesis of novel C-nucleosides with potential applications in combinatorial and parallel synthesis Tetrahedron Letters. 41: 575-578. DOI: 10.1016/S0040-4039(99)02078-X |
0.589 |
|
| 2000 |
Adlington RM, Baldwin JE, Challis GL, Cox RJ, Pritchard GJ. Towards a Biomimetic Synthesis of the Marine Alkaloids Papuamine and Haliclonadiamine: Model Studies Tetrahedron. 56: 623-628. DOI: 10.1016/S0040-4020(99)01011-X |
0.364 |
|
| 2000 |
Fekner T, Baldwin JE, Adlington RM, Jones TW, Prout C, Schofield CJ. Syntheses of (6S)-Cephalosporins from 6-Aminopenicillanic Acid Tetrahedron. 56: 6053-6074. DOI: 10.1016/S0040-4020(00)00486-5 |
0.757 |
|
| 1999 |
Adlington RM, Baldwin JE, Pritchard GJ, Williams AJ, Watkin DJ. A Biomimetic Synthesis of Lucidene Organic Letters. 1: 1937-1939. PMID 10905861 DOI: 10.1021/Ol991068Q |
0.459 |
|
| 1999 |
Baldwin JE, Mayweg AV, Neumann K, Pritchard GJ. Studies toward the biomimetic synthesis of tropolone natural products via a hetero Diels-Alder reaction. Organic Letters. 1: 1933-5. PMID 10905860 DOI: 10.1021/Ol991067Y |
0.403 |
|
| 1999 |
Burzlaff NI, Rutledge PJ, Clifton IJ, Hensgens CM, Pickford M, Adlington RM, Roach PL, Baldwin JE. The reaction cycle of isopenicillin N synthase observed by X-ray diffraction. Nature. 401: 721-4. PMID 10537113 DOI: 10.1038/44400 |
0.817 |
|
| 1999 |
Lloyd MD, Lee HJ, Harlos K, Zhang ZH, Baldwin JE, Schofield CJ, Charnock JM, Garner CD, Hara T, Terwisscha van Scheltinga AC, Valegård K, Viklund JA, Hajdu J, Andersson I, Danielsson A, et al. Studies on the active site of deacetoxycephalosporin C synthase. Journal of Molecular Biology. 287: 943-60. PMID 10222202 DOI: 10.1006/Jmbi.1999.2594 |
0.373 |
|
| 1999 |
Lloyd MD, Lee H, Baldwin JE, Schofield CJ, Charnock JM, Garner CD. Studies on Deacetoxycephalosporin C Synthase Biochemical Society Transactions. 27: A36-A36. DOI: 10.1042/Bst027A036C |
0.324 |
|
| 1999 |
Adlington RM, Baldwin JE, Catterick D, Pritchard GJ. The synthesis of pyrimidin-4-yl substituted α-amino acids. A versatile approach from alkynyl ketones Journal of the Chemical Society-Perkin Transactions 1. 855-866. DOI: 10.1039/A806741D |
0.389 |
|
| 1999 |
Baldwin JE, Vollmer HR, Lee V. Total synthesis of cytotoxic sponge alkaloids motuporamines A and B Tetrahedron Letters. 40: 5401-5404. DOI: 10.1016/S0040-4039(99)01016-3 |
0.34 |
|
| 1999 |
Lloyd MD, Merritt KD, Lee V, Sewell TJ, Wha-Son B, Baldwin JE, Schofield CJ, Elson SW, Baggaley KH, Nicholson NH. Product-substrate engineering by bacteria: Studies on clavaminate synthase, a trifunctional dioxygenase Tetrahedron. 55: 10201-10220. DOI: 10.1016/S0040-4020(99)00547-5 |
0.42 |
|
| 1999 |
Baldwin JE, Beyeler A, Cox RJ, Keats C, Pritchard GJ, Adlington RM, Watkin DJ. Reinvestigation of the dimerisation process forming isoglaucanic acid Tetrahedron. 55: 7363-7374. DOI: 10.1016/S0040-4020(99)00360-9 |
0.504 |
|
| 1999 |
Walter MW, Valladares MH, Adlington RM, Amicosante G, Baldwin JE, Frère JM, Galleni M, Rossolini GM, Schofield CJ. Hydroxamate inhibitors of Aeromonas hydrophila AE036 metallo-β- lactamase Bioorganic Chemistry. 27: 35-40. DOI: 10.1006/Bioo.1998.1111 |
0.577 |
|
| 1999 |
Baldwin JE, Claridge TDW, Culshaw AJ, Heupel FA, Lee V, Spring DR, Whitehead RC. Studies on the Biomimetic Synthesis of the Manzamine Alkaloids Chemistry - a European Journal. 5: 3154-3161. DOI: 10.1002/(Sici)1521-3765(19991105)5:11<3154::Aid-Chem3154>3.0.Co;2-7 |
0.555 |
|
| 1998 |
Baldwin JE, Claridge TDW, Culshaw AJ, Heupel FA, Lee V, Spring DR, Whitehead RC, Boughtflower RJ, Mutton IM, Upton RJ. Investigations into the Manzamine Alkaloid Biosynthetic Hypothesis. Angewandte Chemie (International Ed. in English). 37: 2661-2663. PMID 29711622 DOI: 10.1002/(Sici)1521-3773(19981016)37:19<2661::Aid-Anie2661>3.0.Co;2-D |
0.561 |
|
| 1998 |
Valegård K, van Scheltinga AC, Lloyd MD, Hara T, Ramaswamy S, Perrakis A, Thompson A, Lee HJ, Baldwin JE, Schofield CJ, Hajdu J, Andersson I. Structure of a cephalosporin synthase. Nature. 394: 805-9. PMID 9723623 DOI: 10.1038/29575 |
0.505 |
|
| 1998 |
Walter MW, Adlington RM, Baldwin JE, Schofield CJ. Reaction of (Trifluoromethyl)trimethylsilane with Oxazolidin-5-ones: Synthesis of Peptidic and Nonpeptidic Trifluoromethyl Ketones The Journal of Organic Chemistry. 63: 5179-5192. DOI: 10.1021/Jo980443+ |
0.673 |
|
| 1998 |
Adlington RM, Baldwin JE, Challis GL. Rate enhancement in the reduction of (2,3)-α- and (2,3)-β- methylenepenam β-sulfoxides Tetrahedron Letters. 39: 8537-8540. DOI: 10.1016/S0040-4039(98)01893-0 |
0.521 |
|
| 1998 |
Fekner T, Baldwin JE, Adlington RM, Schofield CJ. Unusually stable azetidinone sulfenic acids Tetrahedron Letters. 39: 6983-6986. DOI: 10.1016/S0040-4039(98)01482-8 |
0.615 |
|
| 1998 |
Baldwin JE, Spring DR, Whitehead RC. A novel Diels-Alder approach to hydroisoquinolines Tetrahedron Letters. 39: 5417-5420. DOI: 10.1016/S0040-4039(98)01043-0 |
0.525 |
|
| 1998 |
Baldwin JE, Fryer AM, Pritchard GJ, Spyvee MR, Whitehead RC, Wood ME. Concise syntheses of acromelic acid A and allo-acromelic acid A Tetrahedron Letters. 39: 707-710. DOI: 10.1016/S0040-4039(97)10641-4 |
0.333 |
|
| 1998 |
Baldwin JE, Spring DR, Atkinson CE, Lee V. Efficient synthesis of the sponge alkaloids cyclostellettamines A-F Tetrahedron. 54: 13655-13680. DOI: 10.1016/S0040-4020(98)00842-4 |
0.523 |
|
| 1998 |
Baldwin JE, Fryer AM, Pritchard GJ, Spyvee MR, Whitehead RC, Wood ME. A biomimetic approach to the pyridone rings of the acromelic acids: A concise synthesis of acromelic acid a and an approach to acromelic acid B Tetrahedron. 54: 7465-7484. DOI: 10.1016/S0040-4020(98)00377-9 |
0.371 |
|
| 1998 |
Kenneth Robinson J, Lee V, Claridge TD, Baldwin JE, Schofield CJ. Synthesis of (2S, 3R, 4S), (2S, 3S, 4R)-epoxyprolines and aminohydroxyprolines Tetrahedron. 54: 981-996. DOI: 10.1016/S0040-4020(97)10352-0 |
0.387 |
|
| 1998 |
Gibson EJ, Zhang Z, Baldwin JE, Schofield CJ. Substrate analogues and inhibition of ACC oxidase: Conversion of D- valine to iso-butanal Phytochemistry. 48: 619-624. DOI: 10.1016/S0031-9422(97)00965-5 |
0.425 |
|
| 1998 |
Baldwin JE, Claridge TDW, Culshaw AJ, Heupel FA, Lee V, Spring DR, Whitehead RC, Boughtflower RJ, Mutton IM, Upton RJ. Untersuchungen zur Hypothese der Manzaminalkaloid-Biosynthese Angewandte Chemie. 110: 2806-2808. DOI: 10.1002/(Sici)1521-3757(19981002)110:19<2806::Aid-Ange2806>3.0.Co;2-R |
0.45 |
|
| 1998 |
Baldwin JE, Adlington RM, Crouch NP, Pereira IAC. The enzymatic synthesis of isotopically labelled penicillin Ns with isopenicillin N synthase Journal of Labelled Compounds and Radiopharmaceuticals. 41: 1145-1163. DOI: 10.1002/(Sici)1099-1344(199812)41:12<1145::Aid-Jlcr159>3.0.Co;2-2 |
0.517 |
|
| 1997 |
Byford MF, Baldwin JE, Shiau CY, Schofield CJ. The Mechanism of ACV Synthetase. Chemical Reviews. 97: 2631-2650. PMID 11851475 DOI: 10.1021/Cr960018L |
0.38 |
|
| 1997 |
Schofield CJ, Baldwin JE, Byford MF, Clifton I, Hajdu J, Hensgens C, Roach P. Proteins of the penicillin biosynthesis pathway. Current Opinion in Structural Biology. 7: 857-64. PMID 9434907 DOI: 10.1016/S0959-440X(97)80158-3 |
0.667 |
|
| 1997 |
Zhang Z, Barlow JN, Baldwin JE, Schofield CJ. Metal-catalyzed oxidation and mutagenesis studies on the iron(II) binding site of 1-aminocyclopropane-1-carboxylate oxidase. Biochemistry. 36: 15999-6007. PMID 9398335 DOI: 10.1021/Bi971823C |
0.397 |
|
| 1997 |
Shiau CY, Byford MF, Aplin RT, Baldwin JE, Schofield CJ. L-delta-(alpha-Aminoadipoyl)-L-cysteinyl-D-valine synthetase: thioesterification of valine is not obligatory for peptide bond formation. Biochemistry. 36: 8798-806. PMID 9220966 DOI: 10.1021/Bi962932E |
0.43 |
|
| 1997 |
Roach PL, Clifton IJ, Hensgens CM, Shibata N, Schofield CJ, Hajdu J, Baldwin JE. Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation. Nature. 387: 827-30. PMID 9194566 DOI: 10.1038/42990 |
0.628 |
|
| 1997 |
Barlow JN, Zhang Z, John P, Baldwin JE, Schofield CJ. Inactivation of 1-aminocyclopropane-1-carboxylate oxidase involves oxidative modifications. Biochemistry. 36: 3563-9. PMID 9132007 DOI: 10.1021/Bi962521Y |
0.365 |
|
| 1997 |
Sami M, Brown TJ, Roach PL, Schofield CJ, Baldwin JE. Glutamine-330 is not essential for activity in isopenicillin N synthase from Aspergillus nidulans. Febs Letters. 405: 191-4. PMID 9089289 |
0.388 |
|
| 1997 |
Barlow JN, Baldwin JE, Clifton IJ, Gibson E, Hensgens CM, Hajdu J, Hara T, Hassan A, John P, Lloyd MD, Roach PL, Prescott A, Robinson JK, Zhang ZH, Schofield CJ. Studies on non-haem ferrous-dependent oxygenases and oxidases. Biochemical Society Transactions. 25: 86-90. PMID 9056849 DOI: 10.1042/Bst0250086 |
0.563 |
|
| 1997 |
Adlington RM, Baldwin JE, MC Coull W, Pritchard GJ, Schofield CJ, Westwood NJ. An Investigation of the N-Arylsulfonylation of 2-Azetidinones Synthetic Communications. 27: 3803-3813. DOI: 10.1080/00397919708007305 |
0.715 |
|
| 1997 |
Uno H, Baldwin J, Churcher I, Russell A. Stereocontrolled Mukaiyama-type Aldol Reaction of Siloxypyrroles Derived from (S)-Glutamic Acid Synlett. 1997: 390-392. DOI: 10.1055/S-1997-798 |
0.333 |
|
| 1997 |
Baldwin JE, Chen D, Russell AT. On the synthesis of vinyl isonitriles Chemical Communications. 2389-2390. DOI: 10.1039/A706830A |
0.36 |
|
| 1997 |
Thirkettle JE, Baldwin JE, Edwards J, Griffin JP, Schofield CJ. The origin of the β-lactam carbons of clavulanic acid Chemical Communications. 1025-1026. DOI: 10.1039/A701934C |
0.453 |
|
| 1997 |
Adlington RM, Baldwin JE, Chen B, Cooper SL, McCoull W, Pritchard GJ, Howe TJ, Becker GW, Hermann RB, McNulty AM, Neubauer BL. Design and synthesis of novel monocyclic β-lactam inhibitors of prostate specific antigen Bioorganic and Medicinal Chemistry Letters. 7: 1689-1694. DOI: 10.1016/S0960-894X(97)00285-0 |
0.531 |
|
| 1997 |
Baldwin JE, Adlington RM, Crouch NP, Hill RL, Wood ME, Lloyd MD. Competing pathways in the oxidation of Z-3-ethylidine cephalosporin C by the enzyme deacetoxycephalosporin C synthase (DAOCS) Bioorganic and Medicinal Chemistry Letters. 7: 593-596. DOI: 10.1016/S0960-894X(97)00052-8 |
0.512 |
|
| 1997 |
Baldwin JE, Spyvee MR, Whitehead RC. A biomimetic synthesis of stizolobinic acid Tetrahedron Letters. 38: 2771-2774. DOI: 10.1016/S0040-4039(97)00467-X |
0.424 |
|
| 1997 |
Crouch NP, Adlington RM, Baldwin JE, Lee MH, MacKinnon CH, Paul DR. Stereochemical course of the conversion of α-ketoisocaproate to β-hydroxyisovalerate by soluble, recombinant mammalian 4-hydroxyphenylpyruvate dioxygenase Tetrahedron. 53: 10827-10840. DOI: 10.1016/S0040-4020(97)00690-X |
0.488 |
|
| 1997 |
Walter MW, Adlington RM, Baldwin JE, Schofield CJ. Synthesis of metallo-β-lactamase inhibitors Tetrahedron. 53: 7275-7290. DOI: 10.1016/S0040-4020(97)00404-3 |
0.6 |
|
| 1997 |
Baldwin JE, Adlington RM, Bryans JS, Lloyd MD, Sewell TJ, Schofield CJ, Baggaley KH, Cassels R. Chemo-enzymatic synthesis of bicyclic γ-lactams using clavaminic acid synthase Tetrahedron. 53: 7011-7020. DOI: 10.1016/S0040-4020(97)00399-2 |
0.604 |
|
| 1997 |
Crouch NP, Adlington RM, Baldwin JE, Lee MH, MacKinnon CH. A mechanistic rationalisation for the substrate specificity of recombinant mammalian 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) Tetrahedron. 53: 6993-7010. DOI: 10.1016/S0040-4020(97)00398-0 |
0.487 |
|
| 1997 |
Baldwin JE, Bischoff L, Claridge TD, Heupel FA, Spring DR, Whitehead RC. An approach to the manzamine alkaloids modelled on a biogenetic theory Tetrahedron. 53: 2271-2290. DOI: 10.1016/S0040-4020(96)01129-5 |
0.376 |
|
| 1996 |
Roach PL, Clifton IJ, Hensgens CM, Shibata N, Long AJ, Strange RW, Hasnain SS, Schofield CJ, Baldwin JE, Hajdu J. Anaerobic crystallisation of an isopenicillin N synthase.Fe(II).substrate complex demonstrated by X-ray studies. European Journal of Biochemistry / Febs. 242: 736-40. PMID 9022704 DOI: 10.1111/J.1432-1033.1996.0736R.X |
0.641 |
|
| 1996 |
Lawrence CC, Sobey WJ, Field RA, Baldwin JE, Schofield CJ. Purification and initial characterization of proline 4-hydroxylase from Streptomyces griseoviridus P8648: a 2-oxoacid, ferrous-dependent dioxygenase involved in etamycin biosynthesis. The Biochemical Journal. 313: 185-91. PMID 8546682 DOI: 10.1042/Bj3130185 |
0.688 |
|
| 1996 |
Shibata N, Baldwin JE, Jacobs A, Wood ME. A Stereocontrolled Synthesis of Protected (2R,3R)-3-Mercaptoaspartic Acid via a β-Aspartyl Enolate Sulfenylation Synlett. 1996: 519-520. DOI: 10.1055/S-1996-5490 |
0.309 |
|
| 1996 |
Fekner T, Baldwin JE, Adlington RM, Schofield CJ. Syntheses of (6S,7S)- and (6S,7R)-deacetoxycephalosporanic acids from 6-aminopenicillanic acid Chemical Communications. 1989-1990. DOI: 10.1039/Cc9960001989 |
0.453 |
|
| 1996 |
Adlington RM, Baldwin JE, Croach NP, Lee M, MacKinnon CH, Paul DR. Stereochemistry of hydroxylation during the conversion of α-ketoisocaproate to β-hydroxyisovalerate by 4-hydroxyphenylpyruvate dioxygenase Bioorganic & Medicinal Chemistry Letters. 6: 2721-2724. DOI: 10.1016/S0960-894X(96)00489-1 |
0.489 |
|
| 1996 |
Shibata N, Lloyd MD, Baldwin JE, Schofield CJ. Adipoyl-6-aminopenicillanic acid is a substrate for deacetoxycephalosporin C synthase (DAOCS) Bioorganic & Medicinal Chemistry Letters. 6: 1579-1584. DOI: 10.1016/S0960-894X(96)00278-8 |
0.39 |
|
| 1996 |
Walter MW, Felici A, Galleni M, Soto RP, Adlington RM, Baldwin JE, Frère J, Gololobov M, Schofield CJ. Trifluoromethyl alcohol and ketone inhibitors of metallo-β-lactamases Bioorganic & Medicinal Chemistry Letters. 6: 2455-2458. DOI: 10.1016/0960-894X(96)00453-2 |
0.449 |
|
| 1996 |
Adlington RM, Baldwin JE, Crouch NP, Lee M, MacKinnon CH. Identification and stereochemistry of the product of 4-HPPD catalyzed oxidation of the ketoacid of methionine Bioorganic & Medicinal Chemistry Letters. 6: 2003-2006. DOI: 10.1016/0960-894X(96)00362-9 |
0.33 |
|
| 1996 |
Baldwin JE, Fryer AM, Spyvee MR, Whitehead RC, Wood ME. Stereocontrol in the synthesis of kainoids Tetrahedron Letters. 37: 6923-6924. DOI: 10.1016/0040-4039(96)01522-5 |
0.382 |
|
| 1996 |
Farthing CN, Baldwin JE, Russell AT, Schofield CJ, Spivey AC. Syntheses of (S)-β-pyrazolylalanine and (S)-quisqualic acid from a serine-derived aziridine Tetrahedron Letters. 37: 5225-5226. DOI: 10.1016/0040-4039(96)01061-1 |
0.653 |
|
| 1996 |
Baldwin JE, Farthing CN, Russell AT, Schofield CJ, Spivey AC. Use of (S)-N-tert-butoxycarbonylaziridine-2-carboxylate derivatives for α-amino acid synthesis Tetrahedron Letters. 37: 3761-3764. DOI: 10.1016/0040-4039(96)00676-4 |
0.685 |
|
| 1996 |
Shibata N, Baldwin JE, Jacobs A, Wood ME. Electrophilic sulfenylation in a stereocontrolled synthesis of protected (2R,3R)-3-mercaptoaspartic acid from L-aspartic acid Tetrahedron. 52: 12839-12852. DOI: 10.1016/0040-4020(96)00765-X |
0.326 |
|
| 1996 |
Baldwin JE, Adlington RM, Marquess DG, Pitt AR, Porter MJ, Russell AT. Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis; 2. Incubation and interpretation Tetrahedron. 52: 2537-2556. DOI: 10.1016/0040-4020(95)01072-6 |
0.644 |
|
| 1996 |
Baldwin JE, Adlington RM, Marquess DG, Pitt AR, Porter MJ, Russell AT. Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis; 1. Synthesis of tripeptide probes Tetrahedron. 52: 2515-2536. DOI: 10.1016/0040-4020(95)01071-8 |
0.702 |
|
| 1995 |
Shiau CY, Byford MF, Baldwin JE, Schofield CJ. Molecular mechanism of the multifunctional enzyme L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine (ACV) synthetase. Biochemical Society Transactions. 23: 629S. PMID 8654814 DOI: 10.1042/Bst023629S |
0.385 |
|
| 1995 |
Shiau CY, Baldwin JE, Byford MF, Sobey WJ, Schofield CJ. delta-L-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase: the order of peptide bond formation and timing of the epimerisation reaction. Febs Letters. 358: 97-100. PMID 7821439 DOI: 10.1016/0014-5793(94)01320-Z |
0.412 |
|
| 1995 |
Roach PL, Clifton IJ, Fülöp V, Harlos K, Barton GJ, Hajdu J, Andersson I, Schofield CJ, Baldwin JE. Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes. Nature. 375: 700-4. PMID 7791906 DOI: 10.1038/375700A0 |
0.689 |
|
| 1995 |
Blackburn JM, Sutherland JD, Baldwin JE. A heuristic approach to the analysis of enzymic catalysis: reaction of delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alpha-aminobutyrate and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-allylglycine catalyzed by isopenicillin N synthase isozymes. Biochemistry. 34: 7548-62. PMID 7779800 DOI: 10.1021/Bi00022A031 |
0.704 |
|
| 1995 |
Zhang Z, Schofield CJ, Baldwin JE, Thomas P, John P. Expression, purification and characterization of 1-aminocyclopropane-1-carboxylate oxidase from tomato in Escherichia coli. The Biochemical Journal. 307: 77-85. PMID 7717997 DOI: 10.1042/Bj3070077 |
0.421 |
|
| 1995 |
Roach PL, Schofield CJ, Baldwin JE, Clifton IJ, Hajdu J. Crystallization and preliminary X-ray diffraction studies on recombinant isopenicillin N synthase from Aspergillus nidulans. Protein Science : a Publication of the Protein Society. 4: 1007-9. PMID 7663335 DOI: 10.1002/Pro.5560040521 |
0.616 |
|
| 1995 |
Shiau CY, Baldwin JE, Byford MF, Schofield CJ. Delta-L-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase: isolation of L-cysteinyl-D-valine, a 'shunt' product, and implications for the order of peptide bond formation. Febs Letters. 373: 303-6. PMID 7589488 DOI: 10.1016/0014-5793(95)01045-G |
0.404 |
|
| 1995 |
Tobin MB, Cole SC, Miller JR, Baldwin JE, Sutherland JD. Amino-acid substitutions in the cleavage site of acyl-coenzyme A:isopenicillin N acyltransferase from Penicillium chrysogenum: effect on proenzyme cleavage and activity. Gene. 162: 29-35. PMID 7557412 DOI: 10.1016/0378-1119(95)00369-H |
0.54 |
|
| 1995 |
Baldwin JE, Davis SC, Forrest AK, Schofield CJ. Cleavage of the 5-amino-5-carboxy-2-oxapentanoyl side chain from enzymatically synthesised penicillins and cephalosporins Bioorganic and Medicinal Chemistry Letters. 5: 2507-2512. DOI: 10.1016/0960-894X(95)00436-W |
0.436 |
|
| 1995 |
Baldwin JE, Adlington RM, Crouch NP, Hill RL, Laffey TG. An expedient synthesis of trisubstituted allenes Tetrahedron Letters. 36: 7925-7928. DOI: 10.1016/0040-4039(95)01643-V |
0.345 |
|
| 1995 |
Walter MW, Adlington RM, Baldwin JE, Chuhan J, Schofield CJ. Reaction of ruppert’s reagent (TMS-CF3) with Oxazolidinones: Synthesis of protected α-amino trifluoromethylketones Tetrahedron Letters. 36: 7761-7764. DOI: 10.1016/0040-4039(95)01619-S |
0.531 |
|
| 1995 |
Baldwin JE, Bamford SJ, Fryer AM, Wood ME. A versatile approach to acromelic acid analogues Tetrahedron Letters. 36: 4869-4872. DOI: 10.1016/0040-4039(95)00841-Y |
0.388 |
|
| 1995 |
Baldwin JE, Adlington RM, Mitchell MB. Stereocontrolled enantiospecific synthesis of anticapsin Tetrahedron. 51: 5193-5206. DOI: 10.1016/0040-4020(95)98714-S |
0.579 |
|
| 1995 |
Baldwin JE, Adlington RM, Gollins DW, Godfrey CR. The stereospecific synthesis of (2S,3R) 3-carboxyproline and (2S,3R) 3-aminoproline Tetrahedron. 51: 5169-5180. DOI: 10.1016/0040-4020(95)98712-Q |
0.529 |
|
| 1995 |
Baldwin JE, Adlington RM, Russell AT, Smith ML. Carbon based nucleophilic ring opening of activated monocyclic β-lactams; Synthesis and stereochemical assignment of the ACE inhibitor WF-10129 Tetrahedron. 51: 4733-4762. DOI: 10.1016/0040-4020(95)00157-4 |
0.593 |
|
| 1995 |
Baldwin JE, Adlington RM, Crouch NP, Mellor LC, Morgan N, Smith AM, Sutherland JD. Synthesis of (2R,3S)[4-2H3] valine: Application to the study of the ring expansion of penicillin N by deacetoxycephalosporin C synthase from Streptomyces clavuligerus Tetrahedron. 51: 4089-4100. DOI: 10.1016/0040-4020(95)00126-S |
0.566 |
|
| 1994 |
Baldwin JE, Claridge TD, Hulme C, Rodger A, Schofield CJ. Comments on the use of a dichromophoric circular dichroism assay for the identification of beta-turns in peptides. International Journal of Peptide and Protein Research. 43: 180-3. PMID 8200737 DOI: 10.1111/J.1399-3011.1994.Tb00520.X |
0.546 |
|
| 1994 |
Tobin MB, Cole SC, Kovacevic S, Miller JR, Baldwin JE, Sutherland JD. Acyl-coenzyme A: isopenicillin N acyltransferase from Penicillium chrysogenum: effect of amino acid substitutions at Ser227, Ser230 and Ser309 on proenzyme cleavage and activity. Fems Microbiology Letters. 121: 39-46. PMID 8082826 DOI: 10.1111/J.1574-6968.1994.Tb07073.X |
0.55 |
|
| 1994 |
Baldwin JE, Shiau CY, Byford MF, Schofield CJ. Substrate specificity of L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase from Cephalosporium acremonium: demonstration of the structure of several unnatural tripeptide products. The Biochemical Journal. 301: 367-72. PMID 8042979 DOI: 10.1042/Bj3010367 |
0.451 |
|
| 1994 |
Fujishima Y, Nordlund P, Pelosi G, Schofield CJ, Cole SJ, Baldwin JE, Hajdu J. Crystallization and preliminary X-ray diffraction studies on a recombinant isopenicillin N synthase from Cephalosporium acremonium. Journal of Molecular Biology. 242: 712-4. PMID 7932729 DOI: 10.1006/Jmbi.1994.1622 |
0.423 |
|
| 1994 |
Smith JJ, Zhang ZH, Schofield CJ, John P, Baldwin JE. Inactivation of 1-aminocyclopropane-1-carboxylate (ACC) oxidase Journal of Experimental Botany. 45: 521-527. DOI: 10.1093/Jxb/45.5.521 |
0.39 |
|
| 1994 |
Baldwin JE, MacKenzie Turner SC, Moloney MG. Enantioselective Synthesis of Novel Functionalised Prolines via [3 + 2] Cycloadditions of a Chiral Azomethine Ylid Synlett. 1994: 925-928. DOI: 10.1055/S-1994-23050 |
0.538 |
|
| 1994 |
Baldwin JE, Adlington RM, Crouch NP, Drake DJ, Fujishima Y, Elson SW, Baggaley KH. Investigation of the stereospecificity of clavaminic acid synthase in the desaturation of dihydroclavaminic acid to clavaminic acid Journal of the Chemical Society, Chemical Communications. 1133-1134. DOI: 10.1039/C39940001133 |
0.323 |
|
| 1994 |
Baldwin JE, Adlington RM, Bebbington D, T. Russell A. Asymmetric total synthesis of the individual diastereoisomers of hypoglycin A. Tetrahedron. 50: 12015-12028. DOI: 10.1039/C39920001249 |
0.599 |
|
| 1994 |
Morgan N, Pereira IAC, Andersson IA, Adlington RM, Baldwin JE, Cole SCJ, Crouch NP, Sutherland JD. Substrate specificity of recombinant Streptomyces clavuligerus deacetoxycephalosporin C synthase Bioorganic and Medicinal Chemistry Letters. 4: 1595-1600. DOI: 10.1016/S0960-894X(01)80573-4 |
0.476 |
|
| 1994 |
Baldwin JE, Spyvee MR, Whitehead RC. Biomimetic syntheses of stizolobic acid and 3-(6-carboxy-2-oxo-4-pyridyl)alanine Tetrahedron Letters. 35: 6575-6576. DOI: 10.1016/S0040-4039(00)78276-1 |
0.31 |
|
| 1994 |
Baldwin JE, Fujishima Y, Goh K, Schofield CJ. Enzymes of valclavam biosynthesis Tetrahedron Letters. 35: 2783-2786. DOI: 10.1016/S0040-4039(00)77032-8 |
0.468 |
|
| 1994 |
Baldwin JE, Goh K, Schofield CJ. Biosynthetic precursors of valclavam Tetrahedron Letters. 35: 2779-2782. DOI: 10.1016/S0040-4039(00)77031-6 |
0.419 |
|
| 1994 |
Baldwin JE, Chan RY, Sutherland JD. Novel stereochemical manipulations of the penicillin nucleus Tetrahedron Letters. 35: 5519-5522. DOI: 10.1016/S0040-4039(00)73540-4 |
0.57 |
|
| 1994 |
Baldwin JE, Field RA, Lawrence CC, Lee V, Robinson J, Schofield CJ. Substrate specificity of proline-4-hydroxylase: Chemical and enzymatic synthesis of 2S,3R,4S-epoxyproline Tetrahedron Letters. 35: 4649-4652. DOI: 10.1016/S0040-4039(00)60753-0 |
0.666 |
|
| 1994 |
Baldwin JE, MacKenzie Turner SC, Moloney MG. The synthesis of substituted pyrrolidines by a Samarium (II) iodide-mediated ring closure. Part 1 Tetrahedron. 50: 9411-9424. DOI: 10.1016/S0040-4020(01)85516-2 |
0.513 |
|
| 1994 |
Lawlor EJ, Elson SW, Holland S, Cassels R, Hodgson JE, Lloyd MD, Baldwin JE, Schofield CJ. Expression in Escherichia coli of a clavaminic acid synthase isozyme: A trifunctional oxygenase involved in clavulanic acid biosynthesis Tetrahedron. 50: 8737-8748. DOI: 10.1016/S0040-4020(01)85347-3 |
0.47 |
|
| 1994 |
Kuo Y, Lambein F, Mellor LC, Adlington RM, Baldwin JE. Ring-nitrogen of β-isoxazolinone-alanine is incorporated into the neurotoxin β-N-oxalyl-l-α,β-diaminopropionic acid, in callus tissue of Lathyrus sativus Phytochemistry. 37: 713-715. DOI: 10.1016/S0031-9422(00)90344-3 |
0.583 |
|
| 1994 |
Baldwin JE, Rudolph M. A concise approach to kainoid analogues Tetrahedron Letters. 35: 6163-6166. DOI: 10.1016/0040-4039(94)88105-7 |
0.371 |
|
| 1993 |
Aplin RT, Baldwin JE, Roach PL, Robinson CV, Schofield CJ. Investigations into the post-translational modification and mechanism of isopenicillin N:acyl-CoA acyltransferase using electrospray mass spectrometry. The Biochemical Journal. 294: 357-63. PMID 8396910 DOI: 10.1042/Bj2940357 |
0.367 |
|
| 1993 |
Aplin RT, Baldwin JE, Cole SC, Sutherland JD, Tobin MB. On the production of alpha, beta-heterodimeric acyl-coenzyme A: isopenicillin N-acyltransferase of Penicillium chrysogenum. Studies using a recombinant source. Febs Letters. 319: 166-70. PMID 8384123 DOI: 10.1016/0014-5793(93)80060-8 |
0.512 |
|
| 1993 |
Randall CR, Zang Y, True AE, Que L, Charnock JM, Garner CD, Fujishima Y, Schofield CJ, Baldwin JE. X-ray absorption studies of the ferrous active site of isopenicillin N synthase and related model complexes. Biochemistry. 32: 6664-73. PMID 8329393 DOI: 10.1021/Bi00077A020 |
0.477 |
|
| 1993 |
Tobin MB, Baldwin JE, Cole SC, Miller JR, Skatrud PL, Sutherland JD. The requirement for subunit interaction in the production of Penicillium chrysogenum acyl-coenzyme A:isopenicillin N acyltransferase in Escherichia coli. Gene. 132: 199-206. PMID 8224864 DOI: 10.1016/0378-1119(93)90196-A |
0.499 |
|
| 1993 |
Baldwin JE, Adlington RM, Godfrey CRA, Gollins DW, Smith ML, Russel AT. A New Approach to the Synthesis of γ-Keto-α-Amino Acids: Synthesis of Optically Pure 5-Hydroxy-4-oxo-L-norvaline, L-HON Synlett. 1993: 51-53. DOI: 10.1055/S-1993-22345 |
0.553 |
|
| 1993 |
Baldwin JE, Edwards AJ, Farthing CN, Russell AT. The Wittig Reaction of Moncyclic β-Lactams Synlett. 1993: 49-50. DOI: 10.1055/S-1993-22344 |
0.304 |
|
| 1993 |
Baldwin JE, Adlington RM, Mitchell MB. Stereocontrolled enantiospecific synthesis of anticapsin: Revision of the configuration Journal of the Chemical Society, Chemical Communications. 1332-1335. DOI: 10.1039/C39930001332 |
0.519 |
|
| 1993 |
Baldwin JE, Hulme C, Schofield CJ, Edwards AJ. Synthesis of potential β-turn bicyclic dipeptide mimetics Journal of the Chemical Society, Chemical Communications. 935-936. DOI: 10.1039/C39930000935 |
0.607 |
|
| 1993 |
Baldwin JE, Merritt KD, Schofield CJ. Synthesis of L-ornithines stereospecifically deuterated at C-3 Tetrahedron Letters. 34: 3919-3920. DOI: 10.1016/S0040-4039(00)79263-X |
0.382 |
|
| 1993 |
Baldwin JE, Claridge TDW, Kee-Chuan G, Keeping JW, Schofield CJ. Revised structures for Tü 1718B and valclavam Tetrahedron Letters. 34: 5645-5648. DOI: 10.1016/S0040-4039(00)73905-0 |
0.354 |
|
| 1993 |
Baldwin JE, Field RA, Lawrence CC, Merritt KD, Schofield CJ. Proline 4-hydroxylase: Stereochemical course of the reaction Tetrahedron Letters. 34: 7489-7492. DOI: 10.1016/S0040-4039(00)60161-2 |
0.639 |
|
| 1993 |
Baldwin JE, Byford MF, Field RA, Shiau C, Sobey WJ, Schofield CJ. Exchange of the valine 2-H in the biosynthesis of L-δ-(α-aminoadipoyl)-L-Cysteinyl-D-valine Tetrahedron. 49: 3221-3226. DOI: 10.1016/S0040-4020(01)89904-X |
0.689 |
|
| 1993 |
Baldwin JE, Adlington RM, Godfrey CR, Patel VK. Stereospecific synthesis of chlamydocin Tetrahedron. 49: 7837-7856. DOI: 10.1016/S0040-4020(01)88010-8 |
0.41 |
|
| 1993 |
Baldwin JE, Spivey AC, Schofield CJ, Sweeney JB. Amino acid synthesis via ring opening of N-sulphonyl aziridine-2-carboxylate esters with organometallic reagents Tetrahedron. 49: 6309-6330. DOI: 10.1016/S0040-4020(01)87968-0 |
0.64 |
|
| 1993 |
Baldwin JE, Adlington RM, Crouch NP, Pereira IA. Incorporation of 18O-labelled water into oxygenated products produced by the enzyme deacetoxy/deacetylcephalosporin C synthase Tetrahedron. 49: 7499-7518. DOI: 10.1016/S0040-4020(01)87226-4 |
0.535 |
|
| 1993 |
Baldwin JE, Adlington RM, Crouch NP, Pereira IA. Evidence for epoxidase activity in deacetoxy/deacetylcephalosporin C synthase Tetrahedron. 49: 4907-4922. DOI: 10.1016/S0040-4020(01)80408-7 |
0.548 |
|
| 1993 |
Baldwin JE, Hulme C, Edwards AJ, Schofield CJ, Parkes KE. Synthesis of a bicyclic γ-lactam dipeptide analogue Tetrahedron Letters. 34: 1665-1668. DOI: 10.1016/0040-4039(93)85036-V |
0.655 |
|
| 1992 |
Baldwin JE, Goh KC, Schofield CJ. Oxidation of deacetylcephalosporin C by deacetoxycephalosporin C/deacetylcephalosporin C synthase. The Journal of Antibiotics. 45: 1378-81. PMID 1399861 DOI: 10.7164/Antibiotics.45.1378 |
0.318 |
|
| 1992 |
Baldwin JE, Adlington RM, Ramcharitar SH. A Short Asymmetric Synthesis of (R,R)-(-)-Pyrenophorin Synlett. 1992: 875-877. DOI: 10.1055/S-1992-21524 |
0.433 |
|
| 1992 |
Baldwin JE, Lee V, Schofield CJ. Comments on the Use of Diphenyloxazinone Derivatives as Glycine Anion Templates for Amino Acid Synthesis Synlett. 1992: 249-251. DOI: 10.1055/S-1992-21332 |
0.438 |
|
| 1992 |
Baldwin JE, Adlington RM, Crouch NP, Heath RJ, Pereira IAC, Sutherland JD. Substrate specificity of soluble recombinant deacetoxycephalosporin C/deacetylcephalosporin C synthase Bioorganic and Medicinal Chemistry Letters. 2: 669-672. DOI: 10.1016/S0960-894X(00)80387-X |
0.467 |
|
| 1992 |
Baldwin JE, Blackburn JM, Heath RJ, Sutherland JD. High-level soluble expression and purification of deacetoxycephalosporin C/deacetylcephalosporin C synthase Bioorganic and Medicinal Chemistry Letters. 2: 663-668. DOI: 10.1016/S0960-894X(00)80386-8 |
0.663 |
|
| 1992 |
Baldwin JE, Adlington RM, Ramcharitar SH. Intramolecular palladium-catalysed cross coupling; a direct route to γ-Oxo-α,β-unsaturated macrocycles. Tetrahedron. 48: 2957-2976. DOI: 10.1016/S0040-4020(01)90977-9 |
0.563 |
|
| 1992 |
Baldwin JE, Adlington RM, Aplin RT, Crouch NP, Wilkinson R. Cephalosporin C biosynthesis : On the mechanism of hydroxylation of deacetoxycephalosporin C to deacetylcephalosporin C. Tetrahedron. 48: 6853-6862. DOI: 10.1016/S0040-4020(01)89876-8 |
0.512 |
|
| 1992 |
Baldwin JE, Adlington RM, Bird JW, Field RA, O'Callaghan NM, Schofield CJ. Studies on the exchange of valine-oxygen during the biosynthesis of δ-(L-α-Aminoadipoyl)-L-cysteinyl-D-valine. Tetrahedron. 48: 1099-1108. DOI: 10.1016/S0040-4020(01)88205-3 |
0.753 |
|
| 1992 |
Baldwin JE, Moloney MG, Parsons AF. An intramolecular cobalt cyclisation for the construction of substituted pyrrolidines. Tetrahedron. 48: 9373-9384. DOI: 10.1016/S0040-4020(01)85626-X |
0.583 |
|
| 1992 |
Baldwin JE, MacKenzie Turner SC, Moloney MG. The synthesis of substituted pyrrolidines by a samarium (II) iodide mediated ring closure. Tetrahedron Letters. 33: 1517-1520. DOI: 10.1016/S0040-4020(01)85516-2 |
0.557 |
|
| 1992 |
Baldwin JE, Lynch GP, Schofield CJ. Isopenicilin N synthase: a new mode of reactivity Tetrahedron. 48: 9085-9100. DOI: 10.1016/S0040-4020(01)82003-2 |
0.549 |
|
| 1992 |
Baldwin JE, Adlington RM, Ramcharitar SH. Free radical macrocyclisation via propiolate esters. Tetrahedron. 48: 3413-3428. DOI: 10.1016/0040-4020(92)85015-7 |
0.574 |
|
| 1992 |
Baldwin JE, Adlington RM, Singh R. Carbocyclic ring expansion reactions via free radical pathways - part III Tetrahedron. 48: 3385-3412. DOI: 10.1016/0040-4020(92)85014-6 |
0.549 |
|
| 1991 |
Baldwin JE, Bird JW, Field RA, O'Callaghan NM, Schofield CJ, Willis AC. Isolation and partial characterisation of ACV synthetase from Cephalosporium acremonium and Streptomyces clavuligerus. Evidence for the presence of phosphopantothenate in ACV synthetase. The Journal of Antibiotics. 44: 241-8. PMID 2010361 DOI: 10.7164/Antibiotics.44.241 |
0.711 |
|
| 1991 |
Baldwin JE, Martin SL, Sutherland JD. Site-specific forced misincorporation mutagenesis using modified T7 DNA polymerase. Protein Engineering. 4: 579-84. PMID 1891465 DOI: 10.1093/protein/4.5.579 |
0.451 |
|
| 1991 |
Baldwin JE, O'Neil IA, Russell AT. Isonitrin A: Revision of the Structure and Total Synthesis in Racemic Form Synlett. 1991: 551-552. DOI: 10.1055/S-1991-20792 |
0.343 |
|
| 1991 |
Baldwin JE, Adlington RM, Crouch NP, Keeping JW, Leppard SW, Pitlik J, Schofield CJ, Sobey WJ, Wood ME. Studies on the mechanism of deacetoxy-deacetylcephalosporin C synthase using cyclopropyl substituted cephalosporin probes Journal of the Chemical Society, Chemical Communications. 768-770. DOI: 10.1039/C39910000768 |
0.526 |
|
| 1991 |
Baldwin JE, Claridge TD, Derome AE, Schofield CJ, Smith BD. 11B NMR studies of an aryl boronic acid bound to chymotrypsin and subtilisin Bioorganic & Medicinal Chemistry Letters. 1: 9-12. DOI: 10.1016/S0960-894X(01)81080-5 |
0.564 |
|
| 1991 |
Aplin RT, Baldwin JE, Pichon C, Roessner CA, Ian Scott A, Schofield CJ, Stolowich NJ, Warren MJ. Observation of enzyme bound intermediates in the biosynthesis of preuroporphyrinogen by PBG deaminase Bioorganic & Medicinal Chemistry Letters. 1: 503-506. DOI: 10.1016/S0960-894X(01)80453-4 |
0.347 |
|
| 1991 |
Baldwin JE, Goh KC, Wood ME, Schofield CJ, Cooper RDG, Huffman GW. The role of sulphur in cephalosporin biosynthesis Bioorganic and Medicinal Chemistry Letters. 1: 421-424. DOI: 10.1016/S0960-894X(00)80269-3 |
0.363 |
|
| 1991 |
Baldwin JE, Moloney MG, Bo Shim S. ()-pyroglutamic acid as a chiral starting material for asymmetric synthesis Tetrahedron Letters. 32: 1379-1380. DOI: 10.1016/S0040-4039(00)79672-9 |
0.61 |
|
| 1991 |
Baldwin JE, Bradley M, Turner NJ, Adlington RM, Pitt AR, Derome AE. Enzymic conversion of deuterated analogues of δ--α-aminoadipoyl--cysteinyl--allylglycine, an unnatural substrate for isopenicilin n synthase: A unified theory of second ring closure. Tetrahedron. 47: 8223-8242. DOI: 10.1016/S0040-4020(01)91016-6 |
0.608 |
|
| 1991 |
Baldwin JE, Bradley M, Turner NJ, Adlington RM, Pitt AR, Sheridan H. Synthesis of δ-L-α-aminoadipoyl-L-cysteinyl-D-allylglycine, and eight deuterated analogues, substrates for the investigation of the mechanism of action of isopenicillin n synthase Tetrahedron. 47: 8203-8222. DOI: 10.1016/S0040-4020(01)91015-4 |
0.811 |
|
| 1991 |
Baldwin J, Bradley M, Adlington R, Norris W, Turner N. Further evidence for the involvement of a monocyclic β-lactam in the enzymatic conversion of δ-L-α-aminoadipoyl-L-cysteinyl-D-valine into isopenicillin N. Tetrahedron. 47: 457-480. DOI: 10.1016/S0040-4020(01)90503-4 |
0.39 |
|
| 1991 |
Baldwin JE, Bradley M, Abbott SD, Adlington RM. New penicillins from isopenicillin N synthase. Tetrahedron. 47: 5309-5328. DOI: 10.1016/S0040-4020(01)87142-8 |
0.58 |
|
| 1991 |
Baldwin JE, Adlington RM, Mitchell MB, Robertson J. Intramolecular SH2′ macrocyclisations Tetrahedron. 47: 5901-5918. DOI: 10.1016/S0040-4020(01)86541-8 |
0.71 |
|
| 1991 |
Baldwin JE, Adlington RM, Godfrey CR, Gollins DW, Schofield CJ. The Stereospecific Synthesis of alahopcin Tetrahedron. 47: 5835-5840. DOI: 10.1016/S0040-4020(01)86533-9 |
0.557 |
|
| 1991 |
Baldwin JE, Blackburn JM, Sutherland JD, Wright MC. High-level soluble expression of isopenicillin N synthase isozymes in E. coli Tetrahedron. 47: 5991-6002. DOI: 10.1016/S0040-4020(01)86491-7 |
0.661 |
|
| 1991 |
Baldwin JE, Adlington RM, Bryans JS, Bringhen AO, Coates JB, Crouch NP, Lloyd MD, Schofield CJ, Elson SW, Baggaley KH, Cassels R, Nicholson N. Isolation of dihydroclavaminic acid, an intermediate in the biosynthesis of clavulanic acid Tetrahedron. 47: 4089-4100. DOI: 10.1016/S0040-4020(01)86446-2 |
0.56 |
|
| 1991 |
Baldwin JE, Adlington RM, Robertson J. Carbocyclic ring expansion reactions via radical chain processes. Part II. Tetrahedron. 47: 6795-6812. DOI: 10.1016/S0040-4020(01)82331-0 |
0.716 |
|
| 1991 |
Baldwin JE, Jesudason CD, Moloney MG, Morgan DR, Pratt AJ. The synthesis of substituted aryl diazirines. A bifunctional reagent suitable for application to photoaffinity labelling studies Tetrahedron. 47: 5603-5614. DOI: 10.1016/S0040-4020(01)80991-1 |
0.581 |
|
| 1991 |
Baldwin JE, Adlington RM, Crouch NP, Schofield CJ, Turner NJ, Aplin RT. Cephalosporin biosynthesis: A branched pathway sensitive to an isotope effect Tetrahedron. 47: 9881-9900. DOI: 10.1016/S0040-4020(01)80725-0 |
0.626 |
|
| 1991 |
Fujishima Y, Schofield C, Baldwin J, Charnock J, Garner C. Recent physical and mechanistic studies on isopenicillin N synthase Journal of Inorganic Biochemistry. 43: 564. DOI: 10.1016/0162-0134(91)84539-L |
0.33 |
|
| 1991 |
Baldwin JE, Adlington RM, Kang TW. Direct Ring Expansion of Penicillins to 3-Exomethylene Cephalosporins Tetrahedron Letters. 32: 7093-7096. DOI: 10.1016/0040-4039(91)85049-B |
0.554 |
|
| 1991 |
Baldwin JE, Moloney MG, Parsons AF. Enantioselective synthesis of kainoid analogues by cobalt-mediated cyclisations Tetrahedron. 47: 155-172. DOI: 10.1016/0040-4020(91)80018-W |
0.614 |
|
| 1990 |
Aplin RT, Baldwin JE, Schofield CJ, Waley SG. Use of electrospray mass spectrometry to directly observe an acyl enzyme intermediate in beta-lactamase catalysis. Febs Letters. 277: 212-4. PMID 2269358 DOI: 10.1016/0014-5793(90)80847-C |
0.351 |
|
| 1990 |
Baldwin JE, Bird JW, Field RA, O'Callaghan NM, Schofield CJ. Isolation and partial characterisation of ACV synthetase from Cephalosporium acremonium and Streptomyces clavuligerus. The Journal of Antibiotics. 43: 1055-7. PMID 2211358 DOI: 10.7164/Antibiotics.43.1055 |
0.712 |
|
| 1990 |
Aplin RT, Baldwin JE, Fujishima Y, Schofield CJ, Green BN, Jarvis SA. Molecular weight analysis of isopenicillin N synthase by electrospray mass spectrometry. Febs Letters. 264: 215-7. PMID 2192915 DOI: 10.1016/0014-5793(90)80251-D |
0.323 |
|
| 1990 |
Baldwin JE, Blackburn JM, Schofield CJ, Sutherland JD. High level expression in Escherichia coli of a fungal gene under the control of strong promoters. Fems Microbiology Letters. 56: 45-51. PMID 2185127 DOI: 10.1016/0378-1097(90)90122-7 |
0.489 |
|
| 1990 |
Whiteman PA, Abraham EP, Baldwin JE, Fleming MD, Schofield CJ, Sutherland JD, Willis AC. Acyl coenzyme A: 6-aminopenicillanic acid acyltransferase from Penicillium chrysogenum and Aspergillus nidulans. Febs Letters. 262: 342-4. PMID 2110531 DOI: 10.1016/0014-5793(90)80224-7 |
0.596 |
|
| 1990 |
Baldwin JE, Blackburn JM, Schofield CJ. The enzymatic synthesis of 3-aceto-penams using isopenicillin n synthase Biocatalysis and Biotransformation. 3: 129-136. DOI: 10.3109/10242429008992055 |
0.481 |
|
| 1990 |
Baldwin JE, Adlington RM, Mitchell MB, Robertson J. Radical reactions in synthesis: Intramolecular SH2′ macrocyclisations Journal of the Chemical Society, Chemical Communications. 1574-1575. DOI: 10.1039/C39900001574 |
0.697 |
|
| 1990 |
Baldwin JE, Bradley M, Abbott SD, Adlington RM. Formation of novel unsaturated side chain penicillins with isopenicillin N synthase Journal of the Chemical Society, Chemical Communications. 1008-1010. DOI: 10.1039/C39900001008 |
0.409 |
|
| 1990 |
Baldwin JE, Spivey AC, Schofield CJ. Cyclic sulphamidates: New synthetic precursors for β-functionalised α-amino acids Tetrahedron: Asymmetry. 1: 881-884. DOI: 10.1016/S0957-4166(00)82279-X |
0.644 |
|
| 1990 |
Baldwin JE, Schofield CJ, Smith BD. Side chain specificity in the pnzymatic synthesis of eenicillins Tetrahedron. 46: 3019-3028. DOI: 10.1016/S0040-4020(01)88393-9 |
0.593 |
|
| 1990 |
Baldwin JE, Adlington RM, Schofield CJ, Ting H. Penicillin biosynthesis: dependence of substrate stereochemistry on the mode of second ring closure Tetrahedron. 46: 6145-6154. DOI: 10.1016/S0040-4020(01)87936-9 |
0.645 |
|
| 1990 |
Baldwin JE, Moloney MG, Parsons AF. Enantioselective kainoid synthesis by cobalt-mediated cyclisation of an amino acid derivative Tetrahedron. 46: 7263-7282. DOI: 10.1016/S0040-4020(01)87906-0 |
0.62 |
|
| 1990 |
Baldwin JE, McConnaughie AW, Moloney MG, Pratt AJ, Bo Shin S. New photolabile phosphate protecting group Tetrahedron. 46: 6879-6884. DOI: 10.1016/S0040-4020(01)87875-3 |
0.526 |
|
| 1990 |
Baldwin JE, Adlington RM, Gollins DW, Schofield CJ. Stereospecific synthesis of dealanylalahopcin Tetrahedron. 46: 4733-4748. DOI: 10.1016/S0040-4020(01)85592-7 |
0.555 |
|
| 1990 |
Baldwin JE, Lowe C, Schofield CJ. The synthesis of potential γ-lactam antibiotics containing a cycloserine nucleus Tetrahedron Letters. 31: 2211-2212. DOI: 10.1016/0040-4039(90)80111-X |
0.525 |
|
| 1990 |
BALDWIN JE, ADLINGTON RM, GOLLINS DW, SCHOFIELD CJ. ChemInform Abstract: Enantiospecific Synthesis of Dealanylalahopcin (I). Cheminform. 21. DOI: 10.1002/chin.199045327 |
0.442 |
|
| 1990 |
BALDWIN JE, ADLINGTON RM, GOLLINS DW, SCHOFIELD CJ. ChemInform Abstract: Stereospecific Synthesis of Dealanylalahopcin. Cheminform. 21. DOI: 10.1002/chin.199044307 |
0.447 |
|
| 1990 |
BALDWIN JE, SCHOFIELD CJ, SMITH BD. ChemInform Abstract: Side Chain Specificity in the Enzymatic Synthesis of Penicillins. Cheminform. 21. DOI: 10.1002/chin.199036314 |
0.407 |
|
| 1990 |
BALDWIN JE, ADLINGTON RM, O'NEIL IA, SCHOFIELD C, SPIVEY AC, SWEENEY JB. ChemInform Abstract: The Ring Opening of Aziridine-2-carboxylate Esters with Organometallic Reagents. Cheminform. 21. DOI: 10.1002/chin.199021298 |
0.618 |
|
| 1990 |
BALDWIN JE, MIRANDA T, MOLONEY M, HOKELEK T. ChemInform Abstract: Amino Acid Synthesis Using (L)-Pyroglutamic Acid as a Chiral Starting Material. Cheminform. 21. DOI: 10.1002/chin.199015267 |
0.542 |
|
| 1990 |
BALDWIN JE, FREEMAN RT, SCHOFIELD C. ChemInform Abstract: Synthesis of a Novel Bicyclic γ-Lactam Analogue of the 1-Oxapenams. Cheminform. 21. DOI: 10.1002/chin.199009173 |
0.463 |
|
| 1990 |
BALDWIN JE, MOLONEY MG, NORTH M. ChemInform Abstract: Non-Proteinogenic Amino Acid Synthesis: Synthesis of β,γ-Unsaturated α-Amino Acids from Aspartic Acid. Cheminform. 21. DOI: 10.1002/chin.199005269 |
0.617 |
|
| 1990 |
BALDWIN JE, MOLONEY MG, NORTH M. ChemInform Abstract: Non-Proteinogenic Amino Acid Synthesis. The β-Anion Derived from Aspartic Acid, and Its Application to α-Amino Acid Synthesis. Cheminform. 21. DOI: 10.1002/chin.199005268 |
0.544 |
|
| 1989 |
Baldwin JE, Coates JB, Halpern JB, Moloney MG, Pratt AJ. Photoaffinity labelling of isopenicillin N synthetase by laser-flash photolysis. The Biochemical Journal. 261: 197-204. PMID 2775205 DOI: 10.1042/Bj2610197 |
0.571 |
|
| 1989 |
Baldwin JE, Adlington RM, O'Neil IA, Schofield C, Spivey AC, Sweeney JB. The ring opening of aziridine-2-carboxylate esters with organometallic reagents Journal of the Chemical Society, Chemical Communications. 1852-1854. DOI: 10.1039/C39890001852 |
0.655 |
|
| 1989 |
Baldwin JE, Adlington RM, Bird JW, Schofield CJ. The fate of valine-oxygen during penicillin biosynthesis Journal of the Chemical Society - Series Chemical Communications. 1615-1616. DOI: 10.1039/C39890001615 |
0.538 |
|
| 1989 |
Baldwin JE, Adlington RM, Schofield CJ, Sobey WJ, Wood ME. The role of α-ketoglutarate in cephalosporin biosynthesis Journal of the Chemical Society, Chemical Communications. 1012-1015. DOI: 10.1039/C39890001012 |
0.547 |
|
| 1989 |
Baldwin JE, Blackburn JM, Sako M, Schofield CJ. Formation of a novel bicyclic γ-lactam with isopenicillin N synthase Journal of the Chemical Society, Chemical Communications. 970-972. DOI: 10.1039/C39890000970 |
0.465 |
|
| 1989 |
Baldwin JE, Freeman RT, Schofield C. Synthesis of a novel bicyclic γ-lactam analogue of the 1-oxapenams Tetrahedron Letters. 30: 4019-4020. DOI: 10.1016/S0040-4039(00)99312-2 |
0.517 |
|
| 1989 |
Baldwin JE, Yamaguchi Y. A facile route to vinyl isocyanides Tetrahedron Letters. 30: 3335-3338. DOI: 10.1016/S0040-4039(00)99237-2 |
0.362 |
|
| 1989 |
Baldwin JE, Miranda T, Moloney M, Hokelek T. Amino acid synthesis using (L)-pyroglutamic acid as a chiral starting material Tetrahedron. 45: 7459-7468. DOI: 10.1016/S0040-4020(01)89208-5 |
0.623 |
|
| 1989 |
Baldwin JE, Freeman RT, Lowe C, Schofield CJ, Lee E. A γ-lactam analogue of the penems possessing antibacterial activity Tetrahedron. 45: 4537-4550. DOI: 10.1016/S0040-4020(01)89088-8 |
0.516 |
|
| 1989 |
Baldwin JE, Moloney MG, North M. Non-proteinogenic amino acid synthesis: Synthesis of β,γ-unsaturated α-amino acids from asparic acid Tetrahedron. 45: 6319-6330. DOI: 10.1016/S0040-4020(01)85141-3 |
0.59 |
|
| 1989 |
Baldwin JE, Moloney MG, North M. Non-proteinogenic amino acid synthesis. The β-anion derived from aspartic acid, and its application to α-amino acid synthesis. Tetrahedron. 45: 6309-6318. DOI: 10.1016/S0040-4020(01)85140-1 |
0.606 |
|
| 1989 |
Baldwin JE, Adlington RM, Moss N. Synthetic Approaches to 2-Methoxycysteine containing Peptides. The conversion of [(5S)-5-amino-5-carboxy-2-oxapentanoyl]-2-methoxy-(2S)-cysteinyl-(2R)-valine into 10-Oxa-6α-methoxyisopenicillin N by the Enzyme Isopenicillin N Synthase Tetrahedron. 45: 2841-2856. DOI: 10.1016/S0040-4020(01)80113-7 |
0.523 |
|
| 1989 |
Baldwin JE, North M, Flinn A, Moloney MG. Synthesis of nonproteinogenic amino acids part 3: conversion of glutamic acid into γ,δ-unsaturated α-amino acids Tetrahedron. 45: 1465-1474. DOI: 10.1016/0040-4020(89)80145-0 |
0.585 |
|
| 1989 |
Baldwin JE, North M, Flinn A, Moloney MG. Synthesis of nonproteinogenic amino acids part 2: preparation of a synthetic equivalent of the γ anion synthon for asymmetric amino acid synthesis Tetrahedron. 45: 1453-1464. DOI: 10.1016/0040-4020(89)80144-9 |
0.604 |
|
| 1989 |
Baldwin JE, Adlington RM, Robertson J. Carbocyclic ring expansion reactiuon VIA radical chain processes Tetrahedron. 45: 909-922. DOI: 10.1016/0040-4020(89)80003-1 |
0.688 |
|
| 1989 |
Baldwin JE, Adlington RM, Russell MA, Schofield CJ, Wood ME. Syntheses of [2-13C] and [1,2-13C] labelled α-ketoglutaric acid Journal of Labelled Compounds and Radiopharmaceuticals. 27: 1091-1099. DOI: 10.1002/Jlcr.2580270914 |
0.597 |
|
| 1989 |
BALDWIN JE, FREEMAN RT, LOWE C, SCHOFIELD CJ, LEE E. ChemInform Abstract: A γ-Lactam Analogue of the Penems Possessing Antibacterial Activity. Cheminform. 20. DOI: 10.1002/chin.198949310 |
0.375 |
|
| 1989 |
BALDWIN JE, ADLINGTON RM, KANG TW, KING LG, PATEL VK. ChemInform Abstract: Desulfurization of Penicillins with Triphenylstannane. Cheminform. 20. DOI: 10.1002/chin.198942085 |
0.447 |
|
| 1989 |
BALDWIN JE, ADLINGTON RM, MOSS N. ChemInform Abstract: Synthetic Approaches to 2-Methoxycysteine-Containing Peptides. The Conversion of ((5S)-5-Amino-5-carboxy-2-oxapentanoyl)-2-methoxy-(2S)-cysteinyl-(2R)-valine into 10-Oxa-6α-methoxyisopenicillin N by the Enzyme Isopenicillin N Synthase Cheminform. 20. DOI: 10.1002/chin.198936349 |
0.514 |
|
| 1989 |
BALDWIN JE, MOLONEY MG, NORTH M. ChemInform Abstract: Asymmetric Amino Acid Synthesis: Preparation of the β Anion Derived from Aspartic Acid. Cheminform. 20. DOI: 10.1002/chin.198929264 |
0.62 |
|
| 1989 |
BALDWIN JE, NORTH M, FLINN A, MOLONEY MG. ChemInform Abstract: Synthesis of Nonproteinogenic Amino Acids. Part 3. Conversion of Glutamic Acid into γ,δ-Unsaturated α-Amino Acids. Cheminform. 20. DOI: 10.1002/chin.198928304 |
0.522 |
|
| 1989 |
BALDWIN JE, NORTH M, FLINN A, MOLONEY MG. ChemInform Abstract: Synthesis of Nonproteinogenic Amino Acids. Part 2. Preparation of a Synthetic Equivalent of the γ-Anion Synthon for Asymmetric Amino Acid Synthesis. Cheminform. 20. DOI: 10.1002/chin.198928303 |
0.549 |
|
| 1989 |
BALDWIN JE, ADLINGTON RM, KANG TW, LEE E, SCHOFIELD CJ. ChemInform Abstract: The Ring Expansion of Penams to Cephams: A Possible Biomimetic Process. Cheminform. 20. DOI: 10.1002/chin.198904315 |
0.352 |
|
| 1989 |
BALDWIN JE, NORRIS WJ, FREEMAN RT, BRADLEY M, ADLINGTON RM, LONG-FOX S, SCHOFIELD CJ. ChemInform Abstract: γ-Lactam Formation from Tripeptides with Isopenicillin N Synthase. Cheminform. 20. DOI: 10.1002/chin.198903315 |
0.59 |
|
| 1989 |
BALDWIN JE, ADLINGTON RM, LOWE C, O'NEIL IA, SANDERS GL, SCHOFIELD CJ, SWEENEY JB. ChemInform Abstract: Reactions of a Glycidyl Radical Equivalent with 2-Functionalized Allylstannanes. Cheminform. 20. DOI: 10.1002/chin.198903281 |
0.357 |
|
| 1988 |
Baldwin JE, Adlington RM, Crouch NP, Coates JB, Keeping JW, Schofield CJ, Shuttleworth WA, Sutherland JD. Substrate specificity of cloned deacetoxycephalosporin C/deacetylcephalosporin C synthetase. The Journal of Antibiotics. 41: 1694-5. PMID 3198501 DOI: 10.7164/Antibiotics.41.1694 |
0.653 |
|
| 1988 |
Baldwin JE, Adlington RM, King LG, Parisi MF, Sobey WJ, Sutherland JD, Ting HH. Penicillin biosynthesis: Stereochemistry of desaturative and hydroxylative pathways from L-α-aminoadipoyl-L-cysteinyl-D-isodehydrovaline with isopenicillin N synthase Journal of the Chemical Society, Chemical Communications. 1635-1637. DOI: 10.1039/C39880001635 |
0.535 |
|
| 1988 |
Baldwin JE, Norris WJ, Freeman RT, Bradley M, Adlington RM, Long-Fox S, Schofield CJ. γ-lactam formation from tripeptides with isopenicillin N synthase Journal of the Chemical Society, Chemical Transactions. 1128-1130. DOI: 10.1039/C39880001128 |
0.695 |
|
| 1988 |
Baldwin JE, Adlington RM, Lowe C, O'Neil IA, Sanders GL, Schofield CJ, Sweeney JB. Reactions of a glycidyl radical equivalent with 2-functionalised allyl stannanes Journal of the Chemical Society, Chemical Communications. 1030-1031. DOI: 10.1039/C39880001030 |
0.638 |
|
| 1988 |
Baldwin JE, North M, Flinn A, Moloney MG. Stereospecific amino acid synthesis; preparation of the γ-anion derived from glutamic acid Journal of the Chemical Society, Chemical Communications. 828-829. DOI: 10.1039/C39880000828 |
0.616 |
|
| 1988 |
Baldwin JE, Adlington RM, Lajoie GA, Lowe C, Baird PD, Prout K. On the biosynthesis of ethylene: Further evidence for stepwise enzymatic cyclopropane ring cleavage Journal of the Chemical Society, Chemical Communications. 775-777. DOI: 10.1039/C39880000775 |
0.474 |
|
| 1988 |
Baldwin JE, Adlington RM, Robinson NG. Enantiospecific synthesis of -(3; and 3)-(β--ribofuranosyl)-pyroglutamic acids: Possible intermediates in C-nucleoside biosynthesis Tetrahedron Letters. 29: 375-378. DOI: 10.1016/S0040-4039(00)80100-8 |
0.606 |
|
| 1988 |
Baldwin JE, Adlington RM, Crouch NP, Schofield CJ. The enzymatic conversion of exomethylene cephalosporin c into deacetyl cephalosporin c and the role of molecular oxygen in cephalosporin c biosynthesis Tetrahedron. 44: 643-650. DOI: 10.1016/S0040-4020(01)85852-X |
0.581 |
|
| 1988 |
Baldwin JE, North M, Flinn A. Synthesis and rearangement of homoserine derivatives Tetrahedron. 44: 637-642. DOI: 10.1016/S0040-4020(01)85851-8 |
0.393 |
|
| 1988 |
Baldwin JE, Killin SJ, Adlington RM, Spiegel U. Synthesis of n-benzyloxycarbonyl-l-α-aminoadipic acid, α-benzyl ester Tetrahedron. 44: 2633-2636. DOI: 10.1016/S0040-4020(01)81715-4 |
0.605 |
|
| 1988 |
Baldwin JE, Adlington RM, Kang TW, Lee E, Schofield CJ. The ring expansion of penama to cephams: a possible biomimetic process Tetrahedron. 44: 5953-5957. DOI: 10.1016/S0040-4020(01)81453-8 |
0.6 |
|
| 1988 |
BALDWIN JE, NORTH M, FLINN A, MOLONEY MG. ChemInform Abstract: Stereospecific Amino Acid Synthesis. Preparation of the γ-Anion Derived from Glutamic Acid. Cheminform. 19. DOI: 10.1002/chin.198846307 |
0.61 |
|
| 1988 |
BALDWIN JE, ADLINGTON RM, ROBINSON NG. ChemInform Abstract: Enantiospecific Synthesis of L-(3R and 3S)-(β-D-Ribofuranosyl)pyroglutamic Acids: Possible Intermediates in C-Nucleoside Biosynthesis. Cheminform. 19. DOI: 10.1002/chin.198824357 |
0.556 |
|
| 1988 |
BALDWIN JE, ADLINGTON RM, CROUCH NP, SCHOFIELD CJ. ChemInform Abstract: The Enzymatic Conversion of Exomethylene Cephalosporin C into Deacetyl Cephalosporin C and the Role of Molecular Oxygen in Cephalosporin C Biosynthesis. Cheminform. 19. DOI: 10.1002/chin.198821319 |
0.334 |
|
| 1988 |
BALDWIN JE, NORTH M, FLINN A. ChemInform Abstract: Synthesis and Rearrangement of Homoserine Derivatives. Cheminform. 19. DOI: 10.1002/chin.198821300 |
0.49 |
|
| 1987 |
Baldwin JE, Adlington RM, Coates JB, Crabbe MJ, Crouch NP, Keeping JW, Knight GC, Schofield CJ, Ting HH, Vallejo CA. Purification and initial characterization of an enzyme with deacetoxycephalosporin C synthetase and hydroxylase activities. The Biochemical Journal. 245: 831-41. PMID 3663194 DOI: 10.1042/Bj2450831 |
0.642 |
|
| 1987 |
Baldwin JE, Crabbe MJ. A spectrophotometric assay for deacetoxycephalosporin C synthase. Febs Letters. 214: 357-61. PMID 3569531 DOI: 10.1016/0014-5793(87)80087-X |
0.318 |
|
| 1987 |
Baldwin JE, Killin SJ, Pratt AJ, Sutherland JD, Turner NJ, Crabbe MJ, Abraham EP, Willis AC. Purification and characterization of cloned isopenicillin N synthetase. The Journal of Antibiotics. 40: 652-9. PMID 3301770 DOI: 10.7164/Antibiotics.40.652 |
0.504 |
|
| 1987 |
Baldwin JE, Adlington RM, Coates JB, Crabbe MJC, Keeping JW, Knight GC, Nomoto T, Schofield CJ, Ting HH. Enzymatic ring expansion of penicillins to cephalosporins: Side chain specificity Journal of the Chemical Society, Chemical Communications. 374-375. DOI: 10.1039/C39870000374 |
0.609 |
|
| 1987 |
Baldwin JE, Adlington RM, Robinson NG. Nucleophilic ring opening of aziridine-2-carboxylates with Wittig reagents; an enantioefficient synthesis of unsaturated amino acids Journal of the Chemical Society, Chemical Communications. 153-155. DOI: 10.1039/C39870000153 |
0.613 |
|
| 1987 |
Ziegler CB, Harris SM, Baldwin JE. 1,4-Dehydrobromination of 1-bromo-1,2,3-butatrienes: an efficient synthesis of 1,4-disubstituted 1,3-diynes The Journal of Organic Chemistry. 52: 443-446. DOI: 10.1021/Jo00379A025 |
0.345 |
|
| 1987 |
Baldwin JE, Ng SC, Pratt AJ. Synthesis of phenoxyacetyl-N-sulphonyl cycloserine Tetrahedron Letters. 28: 4319-4320. DOI: 10.1016/S0040-4039(00)96496-7 |
0.378 |
|
| 1987 |
Baldwin JE, Dyer RL, Ng SC, Pratt AJ, Russell MA. Application of E. Coli aspartate transaminase to amino acid synthesis Tetrahedron Letters. 28: 3745-3746. DOI: 10.1016/S0040-4039(00)96374-3 |
0.377 |
|
| 1987 |
Baldwin J, North M, Flinn A. A convenient new synthesis of homoserine lactone Tetrahedron Letters. 28: 3167-3168. DOI: 10.1016/S0040-4039(00)96313-5 |
0.444 |
|
| 1987 |
Baldwin J, Nga S, Pratta A, Russella M, Dyerb R. Enzymic synthesis of isotopically labelled L-tyrosine Tetrahedron Letters. 28: 2303-2304. DOI: 10.1016/S0040-4039(00)96109-4 |
0.379 |
|
| 1987 |
Baldwin J, Flinn A. Use of L-aspartic acid β-semialdehyde in the synthesis of more complex non protein amino acids Tetrahedron Letters. 28: 3605-3608. DOI: 10.1016/S0040-4039(00)95547-3 |
0.381 |
|
| 1987 |
Baldwin JE, Adlington RM, Crabbe M, Knight G, Nomoto T, Schofield CJ, Ting H. The emzymatic ring expansion of penicillins to cephalosporins : side chain specificity Tetrahedron. 43: 3009-3014. DOI: 10.1016/S0040-4020(01)86840-X |
0.633 |
|
| 1987 |
Baldwin JE, Adlington RM, C. Crabbe M, Nomoto T, Schofield CJ. An efficient substitute for the α-amimoadipoyl moiety of δ-(-α-aminloadipoytl)--cisteintl--valine in the emzymatic synthesis of penicillins Tetrahedron. 43: 4217-4220. DOI: 10.1016/S0040-4020(01)83463-3 |
0.672 |
|
| 1987 |
Baldwin JE, Pratt AJ, Moloney MG. The synthesis of aryl substituted analogues of phenoxyacetyl-L-cysteinyl-D-valine and phenylacetyl-L-cysteinyl-D-valine. Application to the photoaffinity labeling of isopenicillin N synthetase Tetrahedron. 43: 2565-2575. DOI: 10.1016/S0040-4020(01)81664-1 |
0.592 |
|
| 1987 |
BALDWIN JE, ADLINGTON RM, COATES JB, CRABBE MJC, KEEPING JW, KNIGHT GC, NOMOTO T, SCHOFIELD CJ, TING H. ChemInform Abstract: Enzymatic Ring Expansion of Penicillins to Cephalosporins: Side Chain Specificity. Cheminform. 18. DOI: 10.1002/chin.198741390 |
0.551 |
|
| 1987 |
BALDWIN JE, PRATT AJ, MOLONEY MG. ChemInform Abstract: The Synthesis of Aryl Substituted Analogues of Phenoxyacetyl-L-cysteinyl-D-valine and Phenylacetyl-L-cysteinyl-D-valine. Application to the Photoaffinity Labeling of Isopenicillin N Synthetase. Cheminform. 18. DOI: 10.1002/chin.198741377 |
0.537 |
|
| 1987 |
BALDWIN JE, ADLINGTON RM, ROBINSON NG. ChemInform Abstract: Nucleophilic Ring Opening of Aziridine-2-carboxylates with Wittig Reagents. An Enantioefficient Synthesis of Unsaturated Amino Acids. Cheminform. 18. DOI: 10.1002/chin.198732313 |
0.555 |
|
| 1986 |
Baldwin JE, Adlington RM, Birch DJ, Crawford JA, Sweeney JB. Radical reactions in synthesis: Carbon-carbon bond formation from 2-substituted allyl trialkyl stannanes Journal of the Chemical Society, Chemical Communications. 1339-1340. DOI: 10.1039/C39860001339 |
0.559 |
|
| 1986 |
Baldwin JE, Adlington RM, Flitsch SL, Ting HH, Turner NJ. Penicillin biosynthesis: The origin of hydroxy groups in β-lactams derived from unsaturated substrates Journal of the Chemical Society, Chemical Communications. 1305-1308. DOI: 10.1039/C39860001305 |
0.653 |
|
| 1986 |
Baldwin JE, Adlington RM, Basak A, Flitsch SL, Forrest AK, Ting HH. Penicillin biosynthesis: Structure-reactivity profile of unsaturated substrates for isopenicillin N synthetase Journal of the Chemical Society, Chemical Communications. 273-275. DOI: 10.1039/C39860000273 |
0.743 |
|
| 1986 |
Baldwin JE, Adlington RM, Sweeney JB. Improved synthesis of α-Methylene-γ-lactones via organotin reagents Tetrahedron Letters. 27: 5423-5424. DOI: 10.1016/S0040-4039(00)85228-4 |
0.53 |
|
| 1986 |
Baldwin JE, Lowe C, Schofield CJ, Lee E. A γ-lactam analogue of penems possessing antibacterial activity Tetrahedron Letters. 27: 3461-3464. DOI: 10.1016/S0040-4039(00)84822-4 |
0.415 |
|
| 1986 |
Baldwin JE, Lee E. Synthesis of bicyclic γ-lactams via oxazolidinones Tetrahedron. 42: 6551-6554. DOI: 10.1016/S0040-4020(01)88118-7 |
0.421 |
|
| 1986 |
Baldwin JE, Adlington RM, Jain AU, Kolhe JN, Perry MW. Applications of the thermal ene reaction of aldehyde -butyl- and phenyl- hydrazones Tetrahedron. 42: 4247-4252. DOI: 10.1016/S0040-4020(01)87649-3 |
0.576 |
|
| 1986 |
Baldwin JE, Adlington RM, Bottaro JC, Kolhe JN, Newington IM, Perry MW. Azo anions in synthesis Tetrahedron. 42: 4235-4246. DOI: 10.1016/S0040-4020(01)87648-1 |
0.557 |
|
| 1986 |
Baldwin JE, Adlington RM, Bottaro JC, Kolhe JN, Perry MW, Jain AU. Azo anions in systhesis. pt 1. t-butylhydrazones as acyl-anion equivalents Tetrahedron. 42: 4223-4234. DOI: 10.1016/S0040-4020(01)87647-X |
0.577 |
|
| 1986 |
Baldwin JE, Swanson AG, Cha JK, Murphy JA. Preparation and pyrolysis of substituted ethanoanthracenes - a general synthesis of 2,3-disubstituted anthracenes Tetrahedron. 42: 3943-3956. DOI: 10.1016/S0040-4020(01)87549-9 |
0.352 |
|
| 1986 |
Baldwin JE, Otsuka M, Wallace PM. Synthetic studies on tabtoxin. Synthesis of a naturally occuring inhibitor of glutamine synthetase, tabtoxinine-β-lactam, and analogues Tetrahedron. 42: 3097-3110. DOI: 10.1016/S0040-4020(01)87377-4 |
0.346 |
|
| 1986 |
Baldwin JE, Adlington RM, Jones RH, Schofield CJ, Zaracostas C, Greengrass CW. γ-Lactam analogues of carbapenicillanic acids Tetrahedron. 42: 4879-4888. DOI: 10.1016/S0040-4020(01)82070-6 |
0.641 |
|
| 1986 |
Baldwin JE, Adlington RM, Parisi MF, Ting H. The synthesis and antimicrobial activity of (1,2)-1-hydroxy-2-[(s)-valylamino]cyclobutane-1-acetic acid (1) and (1, 2)-1-hydroxy-2-aminocyclobutane-1-acetic acid (2) Tetrahedron. 42: 2575-2586. DOI: 10.1016/0040-4020(86)80025-4 |
0.576 |
|
| 1986 |
BALDWIN JE, ADLINGTON RM, JAIN AU, KOLHE JN, PERRY MWD. ChemInform Abstract: Applications of the Thermal Ene Reaction of Aldehyde t-Butyl- and Phenylhydrazones. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198652097 |
0.454 |
|
| 1986 |
BALDWIN JE, ADLINGTON RM, BOTTARO JC, KOHLE JN, NEWINGTON IM, PERRY MWD. ChemInform Abstract: Azo Anions in Synthesis. Use of Trityl- and Diphenyl-4-pyridylmethylhydrazones for Reductive C - C Bond Formation. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198652096 |
0.48 |
|
| 1986 |
Baldwin JE, Adlington RM, Basak A, Flitsch SL, Petursson S, Turner NJ, Ting HH. Enzymatic synthesis of a new type of penicillin Journal of the Chemical Society, Chemical Communications. 975-976. DOI: 10.1002/Chin.198649357 |
0.717 |
|
| 1986 |
BALDWIN JE, ADLINGTON RM, BASAK A, FLITSCH SL, PETURSSON S, TURNER NJ, TING H. ChemInform Abstract: Enzymatic Synthesis of a New Type of Penicillin. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198649357 |
0.633 |
|
| 1986 |
BALDWIN JE, LOWE C, SCHOFIELD CJ, LEE E. ChemInform Abstract: A γ-Lactam Analogue of Penems Possessing Antibacterial Activity. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198649351 |
0.375 |
|
| 1986 |
BALDWIN JE, ADLINGTON RM, NEWINGTON IM. ChemInform Abstract: Azo Anions in Synthesis: α-Amino Carbanion Equivalents from tert-Butyldiphenylmethylhydrazones. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198624142 |
0.519 |
|
| 1986 |
BALDWIN JE, ADLINGTON RM, BIRCH DJ. ChemInform Abstract: Synthesis of L-β-(Isoxazolin-S-one-2-yl)-alanine: A Novel Method for the Synthesis of N-Substituted 3,4-Unsubstituted Isoxazolin-5-ones. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198617356 |
0.32 |
|
| 1985 |
Samson SM, Belagaje R, Blankenship DT, Chapman JL, Perry D, Skatrud PL, VanFrank RM, Abraham EP, Baldwin JE, Queener SW. Isolation, sequence determination and expression in Escherichia coli of the isopenicillin N synthetase gene from Cephalosporium acremonium. Nature. 318: 191-4. PMID 3903520 DOI: 10.1038/318191A0 |
0.318 |
|
| 1985 |
Baldwin JE, Moroney SE, Ting HH. A coupled enzyme assay for isopenicillin N synthetase. Analytical Biochemistry. 145: 183-7. PMID 3873879 DOI: 10.1016/0003-2697(85)90345-8 |
0.361 |
|
| 1985 |
Baldwin JE, Gagnon J, Ting H. N-terminal amino acid sequence and some properties of isopenicillin-N synthetase from Cephalosporium acremonium. Febs Letters. 188: 253-6. PMID 3839755 DOI: 10.1016/0014-5793(85)80382-3 |
0.339 |
|
| 1985 |
Baldwin JE, Otsuka M, Wallace PM. Synthesis of a naturally occurring inhibitor of glutamine synthetase, tabtoxinene-β-lactam Journal of the Chemical Society, Chemical Communications. 1549-1550. DOI: 10.1039/C39850001549 |
0.336 |
|
| 1985 |
Baldwin JE, Adlington RM, Chondrogianni J, Edenborough MS, Keeping JW, Ziegler CB. Structure and synthesis of new cyclopentenyl isonitriles from Trichoderma hamatum (Bon.) Bain. aggr. HLX 1379 Journal of the Chemical Society, Chemical Communications. 816-817. DOI: 10.1039/C39850000816 |
0.306 |
|
| 1985 |
Baldwin JE, Adlington RM, Birch DJ. Synthesis of L-quisqualic acid: a general method for enantio-efficient synthesis of β-aminoalanine derivatives Journal of the Chemical Society, Chemical Communications. 256-257. DOI: 10.1039/C39850000256 |
0.598 |
|
| 1985 |
Baldwin JE, Adlington RM, Birch DJ. Synthesis of -β-(isoxazolin-5-one-2-yl)-alanine: a novel method for the synthesis of -substituted 3,4-unsubstituted isoxazolin-5-ones Tetrahedron Letters. 26: 5931-5934. DOI: 10.1016/S0040-4039(00)98264-9 |
0.609 |
|
| 1985 |
Baldwin JE, Adlington RM, Rawlings BJ, Jones RH. The resolution of racemic 2-alkyl-1-aminocyclopropane-1-carboxylic acids Tetrahedron Letters. 26: 485-488. DOI: 10.1016/S0040-4039(00)61918-4 |
0.521 |
|
| 1985 |
Baldwin JE, Adlington RM, Rawlings BJ. A convenient synthesis of regio-specifically 2-alkylated-3-deuteriated-1-aminocyclopropane-1-carboxylic acids Tetrahedron Letters. 26: 481-484. DOI: 10.1016/S0040-4039(00)61917-2 |
0.532 |
|
| 1985 |
Baldwin JE, Adlington RM, Ting HH, Arigoni D, Graf P, Martinoni B. Penicillin biosynthesis the immediate origin of the sulphur atom Tetrahedron. 41: 3339-3343. DOI: 10.1016/S0040-4020(01)96685-2 |
0.717 |
|
| 1985 |
Baldwin JE, Bansal HS, Chondrogianni J, Field LD, Taha AA, Thaller V, Brewer D, Taylor A. Biosynthesis of 3-(3'-isocyanocyclopent-2-enylidene) propionic acid by (bon.) bain. aggr. Tetrahedron. 41: 1931-1938. DOI: 10.1016/S0040-4020(01)96556-1 |
0.37 |
|
| 1985 |
BALDWIN JE, ADLINGTON RM, CHONDROGIANNI J, EDENBOROUGH MS, KEEPING JW, ZIEGLER CB. ChemInform Abstract: STRUCTURE AND SYNTHESIS OF NEW CYCLOPENTENYL ISONITRILES FROM TRICHODERMA HAMATUM (BON.) BAIN. AGGR. HLX 1379 Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198541199 |
0.567 |
|
| 1985 |
BALDWIN JE, ADLINGTON RM, BOHLMANN R. ChemInform Abstract: BIOMIMETIC SYNTHESIS OF PENICILLIN Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198527367 |
0.534 |
|
| 1985 |
BALDWIN JE, ADLINGTON RM, JONES RH, SCHOFIELD CJ, ZAROCOSTAS C, GREENGRASS CW. ChemInform Abstract: γ-Lactam Analogues of Carbapenicillanic Acids. Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198526375 |
0.422 |
|
| 1985 |
BALDWIN JE, ADLINGTON RM, BIRCH DJ. ChemInform Abstract: SYNTHESIS OF L-QUISQUALIC ACID: A GENERAL METHOD FOR ENANTIO-EFFICIENT SYNTHESIS OF β-AMINOALANINE DERIVATIVES Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198526342 |
0.613 |
|
| 1985 |
BALDWIN JE, ADLINGTON RM, BASAK A. ChemInform Abstract: ALLENE TRANSFER REACTIONS. A NEW SYNTHESIS OF TERMINAL ALLENES Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198505135 |
0.675 |
|
| 1985 |
BALDWIN JE, ADLINGTON RM, DEROME AE, TING H, TURNER NJ. ChemInform Abstract: PENICILLIN BIOSYNTHESIS: MULTIPLE PATHWAYS FROM A MODIFIED SUBSTRATE Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198504345 |
0.458 |
|
| 1985 |
BALDWIN JE, ADLINGTON RM, TURNER NJ, DOMAYNE-HAYMAN BP, TING H, DEROME AE, MURPHY JA. ChemInform Abstract: PENICILLIN BIOSYNTHESIS: ENZYMATIC SYNTHESIS OF NEW CEPHAMS Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198502370 |
0.577 |
|
| 1985 |
BALDWIN JE, ADLINGTON RM, BOTTARO JC, JAIN AU, KOLHE JN, PERRY MWD, NEWINGTON IM. ChemInform Abstract: MICHAEL ADDITIONS OF HYDRAZONES FOR CARBON-CARBON BOND FORMATION Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198501145 |
0.486 |
|
| 1984 |
Pang CP, Chakravarti B, Adlington RM, Ting HH, White RL, Jayatilake GS, Baldwin JE, Abraham EP. Purification of isopenicillin N synthetase. The Biochemical Journal. 222: 789-95. PMID 6435606 DOI: 10.1042/Bj2220789 |
0.459 |
|
| 1984 |
Baldwin JE, Beckwith PLM, Wallis JD, Orrell APK, Prout K. An approach to the synthesis of dodecahedrane: the X-ray crystal structures of six intermediate compounds Journal of the Chemical Society-Perkin Transactions 1. 15: 53-61. DOI: 10.1039/P29840000053 |
0.302 |
|
| 1984 |
Baldwin JE, Adlington RM, Basak A. Allene transfer reactions. A new synthesis of terminal allenes Journal of the Chemical Society, Chemical Communications. 1284-1285. DOI: 10.1039/C39840001284 |
0.706 |
|
| 1984 |
Baldwin JE, Abraham EP, Adlington RM. Penicillin biosynthesis: Active site mapping with aminoadipoylcysteinylvaline variants Journal of the Chemical Society - Series Chemical Communications. 1225-1227. DOI: 10.1039/C39840001225 |
0.531 |
|
| 1984 |
Baldwin JE, Adlington RM, Turner NJ, Domayne-Hayman BP, Ting H, Derome AE, Murphy JA. Penicillin biosynthesis: enzymatic synthesis of new cephams Journal of the Chemical Society, Chemical Communications. 1167-1170. DOI: 10.1039/C39840001167 |
0.594 |
|
| 1984 |
Baldwin JE, Adlington RM, Bottaro JC, Jain AU, Kolhe JN, Perry MWD, Newington IM. Michael additions of hydrazones for carbon–carbon bond formation Journal of the Chemical Society, Chemical Communications. 1095-1096. DOI: 10.1039/C39840001095 |
0.569 |
|
| 1984 |
Baldwin JE, Chan MF, Gallacher G, Otsuka M, Monk P, Prout K. γ-Lactam analogues of penicillanic and carbapenicillanic acids Tetrahedron. 40: 4513-4525. DOI: 10.1016/S0040-4020(01)98828-3 |
0.345 |
|
| 1984 |
Baldwin JE, Harwood LM, Lombard MJ. A general procedure for the synthesis of isoxazolidin-5-ones Tetrahedron. 40: 4363-4370. DOI: 10.1016/S0040-4020(01)98811-8 |
0.388 |
|
| 1984 |
Baldwin JE, Abraham SEP, Adlington RM, Crimmin MJ, Field LD, Jayatilake GS, White RL, Usher JJ. The synthesis and reactions of a monocyclic β-lactam tripeptide, 1-[(1R)-carboxy-2-methylpropyl]- (3R -[(5S-5-amino- 5-carboxypentanamido]-(4R)-mercaptoazetidin-2-one, a putative intermediate in penicillin biosynthesis Tetrahedron. 40: 1907-1918. DOI: 10.1016/S0040-4020(01)91148-2 |
0.566 |
|
| 1984 |
Baldwin JE, D. Bailey P, Gallacher G, Otsuka M, Singleton KA, Wallace PM, Prout K, Wolf WM. Stereospecific synthesis of tabtoxin Tetrahedron. 40: 3695-3708. DOI: 10.1016/S0040-4020(01)88799-8 |
0.372 |
|
| 1984 |
BALDWIN JE, BOTTARO JC, KOLHE JN, ADLINGTON RM. ChemInform Abstract: AZO ANIONS IN SYNTHESIS. USE OF TRITYL- AND DIPHENYL-4-PYRIDYLMETHYLHYDRAZONES FOR REDUCTIVE CARBON-CARBON BOND FORMATION FROM ALDEHYDES AND KETONES Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198419157 |
0.468 |
|
| 1984 |
ADLINGTON RM, BALDWIN JE, JONES RH, MURPHY JA, PARISI MF. ChemInform Abstract: STEREOSPECIFIC SYNTHESIS OF (1S,2S)-1-HYDROXY-2-((S)-VALYLAMINO)CYCLOBUTANE-1-ACETIC ACID, A NOVEL MICROBIAL ANTIMETABOLITE Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198417350 |
0.556 |
|
| 1984 |
ADLINGTON RM, BALDWIN JE, BOTTARO JC, PERRY MWD. ChemInform Abstract: AZO ANIONS IN SYNTHESIS. TERT-BUTYLHYDRAZONES AS ACYL ANION EQUIVALENTS Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198403132 |
0.525 |
|
| 1983 |
Adlington RM, Baldwin JE, Lopez-Nieto M, Murphy JA, Patel N. A study of the biosynthesis of the tripeptide delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine in a beta-lactam-negative mutant of Cephalosporium acremonium. The Biochemical Journal. 213: 573-6. PMID 6684424 DOI: 10.1042/Bj2130573 |
0.494 |
|
| 1983 |
Adlington RM, Baldwin JE, Jones RH, Murphy JA, Parisi MF. Stereospecific synthesis of (1S,2S)-1-hydroxy-2-[(S)-valylamino]-cyclobutane-1-acetic acid, a novel microbial antimetabolite Journal of the Chemical Society, Chemical Communications. 1479-1481. DOI: 10.1039/C39830001479 |
0.54 |
|
| 1983 |
Baldwin JE, Abraham EP, Adlington RM, Murphy JA, Green NB, Ting HH, Usher JJ. Penicillin biosynthesis. On the stereochemistry of carbon-sulphur bond formation with modified substrates Journal of the Chemical Society, Chemical Communications. 1319-1320. DOI: 10.1039/C39830001319 |
0.517 |
|
| 1983 |
Adlington RM, Baldwin JE, Chakravarti B, Jung M, Moroney SE, Murphy JA, Singh PD, Usher JJ, Vallejo C. Conversion of 3-exomethylene cephalosporin C into deacetyl cephalosporin C in a cell-free extract from Cephalosporium acremonium(CW-19) Journal of the Chemical Society, Chemical Communications. 153-154. DOI: 10.1039/C39830000153 |
0.481 |
|
| 1983 |
Adlington RM, Aplin RT, Baldwin JE, Chakravarti B, Field LD, John EMM, Abraham EP, White RL. Conversion of 17O/18O labelled δ-(L-α-aminoadlpyl)-L-cysteinyl-D-valine to 17O/18O labelled isopenicillin n in a cell-free extract of cephalosporium acremonium. A study by 17O-NMR spectroscopy and mass spectrometry Tetrahedron. 39: 1061-1068. DOI: 10.1016/S0040-4020(01)91867-8 |
0.505 |
|
| 1983 |
Baldwin JE, Lopez R. Addition reactions of some simple thioaldehydes Tetrahedron. 39: 1487-1498. DOI: 10.1016/S0040-4020(01)88553-7 |
0.317 |
|
| 1983 |
ADLINGTON RM, BALDWIN JE, BASAK A, KOZYROD RP. ChemInform Abstract: APPLICATIONS OF RADICAL ADDITION REACTIONS TO THE SYNTHESIS OF A C-GLUCOSIDE AND A FUNCTIONALIZED AMINO ACID Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198352326 |
0.663 |
|
| 1983 |
ADLINGTON RM, BALDWIN JE, CHAKRAVARTI B, JUNG M, MORONEY SE, MURPHY JA, SINGH PD, USHER JJ, VALLEJO C. ChemInform Abstract: CONVERSION OF 3-EXOMETHYLENE CEPHALOSPORIN C INTO DEACETYL CEPHALOSPORIN C IN A CELL-FREE EXTRACT FROM CEPHALOSPORIUM ACREMONIUM (CW-19) Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198326346 |
0.516 |
|
| 1983 |
ABRAHAM EP, ADLINGTON RM, BALDWIN JE, CRIMMIN MJ, FIELD LD, JAYATILAKE GS, WHITE RL. ChemInform Abstract: MONOCYCLIC β-LACTAM TRIPEPTIDE, 1-(D-CARBOXY-2-METHYLPROPYL)-3-L-(Δ-L-2-AMINOADIPAMIDO)-4-L-MERCAPTOAZETI# DIN-2-ONE, A PUTATIVE INTERMEDIATE IN PENICILLIN BIOSYNTHESIS Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198309319 |
0.499 |
|
| 1983 |
BALDWIN JE, DAVIS AP, FIELD LD. ChemInform Abstract: THE STEREOCHEMISTRY OF CYCLIZATION OF N-TERT-BUTYLDIHYDROCINNAMAMIDE TO A β-LACTAM Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198306091 |
0.487 |
|
| 1982 |
Abraham EP, Adlington RM, Baldwin JE. Monocyclic β-lactam tripeptide, 1-(D-carboxy-2-methylpropyl)-3-L-(δ-L-2- aminoadipamido)-4-L-mercaptoazetidin-2-one, a putative intermediate in penicillin biosynthesis Journal of the Chemical Society - Series Chemical Communications. 1130-1132. DOI: 10.1039/C39820001130 |
0.529 |
|
| 1982 |
Adlington RM, Aplin RT, Baldwin JE, Field LD, John EMM, Abraham EP, White RL. Conversion of 17O/18O-labelled δ-(L-α- aminoadipyl)-L-cysteinyl-D-valine into 17O/18O-labelled isopenicillin N in a cell-free extract of C. acremonium Journal of the Chemical Society, Chemical Communications. 137-139. DOI: 10.1039/C39820000137 |
0.448 |
|
| 1982 |
Baldwin JE, Lusch MJ. Rules for ring closure: application to intramolecular aldol condensations in polyketonic substrates Tetrahedron. 38: 2939-2947. DOI: 10.1016/0040-4020(82)85023-0 |
0.396 |
|
| 1982 |
Baldwin JE, Davis AP, Field LD. The stereochemistry of cyclisation of n--butyldihydrocinnamamide to a β-lactam Tetrahedron. 38: 2777-2781. DOI: 10.1016/0040-4020(82)85003-5 |
0.537 |
|
| 1982 |
Baldwin JE, Chakravarti B, Field LD, Murphy JA, Whitten KR, Abraham SEP, Jayatilake G. The synthesis of l-α-aminoadipyl-l-cysteinyl-d-3,4-didehydrovaline, a potent inhibitor of isopenicillin synthetase Tetrahedron. 38: 2773-2776. DOI: 10.1016/0040-4020(82)85002-3 |
0.376 |
|
| 1981 |
Baldwin JE, Davis AP. Penicillin biosynthesis: A model for the oxidative cyclisation of a peptide to a β-lactam Journal of the Chemical Society, Chemical Communications. 1219-1221. DOI: 10.1039/C39810001219 |
0.48 |
|
| 1981 |
Crout DHG, Lutstorf M, Morgan PJ, Adlington RM, Baldwin JE, Crimmin MJ. Unusual stereospecificity in the hydrogenation of an isopropenyl function with Wilkinson's catalyst; a route to chiral methyl valine Journal of the Chemical Society, Chemical Communications. 1175-1176. DOI: 10.1039/C39810001175 |
0.459 |
|
| 1981 |
Ross WJ, Todd A, Clark BP, Morgan SE, Baldwin JE. The synthesis and rearrangement of epoxypyrones Tetrahedron Letters. 22: 2207-2208. DOI: 10.1016/S0040-4039(01)90499-X |
0.39 |
|
| 1981 |
Baldwin JE, Beckwith ALJ, Davis AP, Procter G, Singleton KA. 5-Isothiazolidinonyl and 5-isoxazolidinonyl radicals. Approaches to the biogenetic-type synthesis of β-lactams Tetrahedron. 37: 2181-2189. DOI: 10.1016/S0040-4020(01)97977-3 |
0.485 |
|
| 1980 |
Baldwin JE, Cacioli P, Reiss JA. Phenoxathiins from spiroepoxycyclohexadienones Tetrahedron Letters. 21: 4971-4972. DOI: 10.1016/S0040-4039(00)71168-3 |
0.307 |
|
| 1979 |
Baldwin JE, Lusch MJ. Rearrangements in Lewis acid catalyzed Diels-Alder reactions. Route to substituted bicyclo[2.2.1]heptanones The Journal of Organic Chemistry. 44: 1923-1927. DOI: 10.1021/Jo01326A006 |
0.387 |
|
| 1979 |
Baldwin J, Singh P. Model studies towards the synthesis of 2-β-hydroxymethyl penicillin N Tetrahedron Letters. 20: 3757-3760. DOI: 10.1016/S0040-4039(01)95517-0 |
0.352 |
|
| 1977 |
Davies DI, Hughes L, Vankar YD, Baldwin JE. Synthesis of 1,4-oxathian-2-one, 5-methyl-1,4-oxathian-2-one, and 1,4-oxathiepan-2-one Journal of the Chemical Society-Perkin Transactions 1. 9: 2476-2479. DOI: 10.1039/P19770002476 |
0.334 |
|
| 1975 |
Almog J, Baldwin JE, Dyer RL, Peters M. Condensation of tetraaldehydes with pyrrole. Direct synthesis of capped porphyrins Journal of the American Chemical Society. 97: 226-227. DOI: 10.1021/Ja00834A059 |
0.367 |
|
| 1971 |
Baldwin JE, Barton DH, Gutteridge NJ, Martin RJ. Experiments on the synthesis of tetracycline. IV. Ring B formation through 1,3-dipolar additions. Journal of the Chemical Society. Perkin Transactions 1. 12: 2184-92. PMID 5170047 DOI: 10.1039/J39710002184 |
0.647 |
|
| 1971 |
Aufderhaar E, Baldwin JE, Barton DH, Faulkner DJ, Slaytor M. Experiments on the synthesis of tetracycline. 3. Michael-type cyclisation in the formation of ring B. Journal of the Chemical Society. Perkin Transactions 1. 12: 2175-83. PMID 5170046 DOI: 10.1039/J39710002175 |
0.705 |
|
| 1971 |
AUFDERHAAR E, BALDWIN JE, BARTON DHR, FAULKNER DJ, SLAYTOR M. ChemInform Abstract: VERSUCHE ZUR SYNTH. VON TETRACYCLIN 3. MITT. CYCLISIERUNG VOM MICHAEL-TYP BEI DER BLDG. VON RING B Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/chin.197139390 |
0.416 |
|
| 1968 |
Baldwin JE, Barton DH, Dainis I, Pereira JL. Photochemical transformations. XXIV. The synthesis of 18-hydroxyoestrone. Journal of the Chemical Society. Perkin Transactions 1. 18: 2283-9. PMID 5693074 |
0.626 |
|
| 1962 |
BALDWIN JE, BARTON DH, BLOOMER JL, JACKMAN LM, RODRIGUEZ-HAHN L, SUTHERLAND JK. The constitutions of glauconic, glaucanic and byssochlamic acids. Experientia. 18: 345-52. PMID 13864341 DOI: 10.1007/BF02172243 |
0.721 |
|
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