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Holly A. Ingraham - Publications

Affiliations: 
Cellular and Molecular Pharmacology University of California, San Francisco, San Francisco, CA 
Area:
Nuclear Receptors, Neuroendocrinology
Website:
http://ingrahamlab.ucsf.edu/

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Krause WC, Rodriguez R, Gegenhuber B, Matharu N, Rodriguez AN, Padilla-Roger AM, Toma K, Herber CB, Correa SM, Duan X, Ahituv N, Tollkuhn J, Ingraham HA. Oestrogen engages brain MC4R signalling to drive physical activity in female mice. Nature. PMID 34646010 DOI: 10.1038/s41586-021-04010-3  0.547
2019 Herber CB, Ingraham HA. Should We Make More Bone or Not, As Told by Kisspeptin Neurons in the Arcuate Nucleus. Seminars in Reproductive Medicine. 37: 147-150. PMID 31869843 DOI: 10.1055/S-0039-3400238  0.332
2019 Herber CB, Krause WC, Wang L, Bayrer JR, Li A, Schmitz M, Fields A, Ford B, Zhang Z, Reid MS, Nomura DK, Nissenson RA, Correa SM, Ingraham HA. Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones. Nature Communications. 10: 163. PMID 30635563 DOI: 10.1038/S41467-018-08046-4  0.547
2019 Choksi PK, Ingraham HA, Bayrer J. 948 – Nuclear Receptor Liver Receptor Homolog-1 Promotes Intestinal Notch Signaling and Enteroendocrine Cell Development Gastroenterology. 156: S-202. DOI: 10.1016/S0016-5085(19)37298-1  0.392
2018 Bayrer JR, Wang H, Nattiv R, Suzawa M, Escusa HS, Fletterick RJ, Klein OD, Moore DD, Ingraham HA. LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. Nature Communications. 9: 4055. PMID 30305617 DOI: 10.1038/S41467-018-06137-W  0.515
2018 Miranda DA, Krause WC, Cazenave-Gassiot A, Suzawa M, Escusa H, Foo JC, Shihadih DS, Stahl A, Fitch M, Nyangau E, Hellerstein M, Wenk MR, Silver DL, Ingraham HA. LRH-1 regulates hepatic lipid homeostasis and maintains arachidonoyl phospholipid pools critical for phospholipid diversity. Jci Insight. 3. PMID 29515023 DOI: 10.1172/Jci.Insight.96151  0.309
2018 Bayrer J, Escusa H, Kein OD, Ingraham H. 273 - Nuclear Receptor LRH-1 Mitigates Intestinal Inflammatory Disease by Promoting Stem Cell Survival and Directing Normal Epithelial Composition Gastroenterology. 154: S-67. DOI: 10.1016/S0016-5085(18)30680-2  0.315
2017 Krause WC, Ingraham HA. Origins and Functions of the Ventrolateral VMH: A Complex Neuronal Cluster Orchestrating Sex Differences in Metabolism and Behavior. Advances in Experimental Medicine and Biology. 1043: 199-213. PMID 29224096 DOI: 10.1007/978-3-319-70178-3_10  0.304
2017 Xing Y, Morohashi KI, Ingraham HA, Hammer GD. Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1. Development (Cambridge, England). PMID 28893949 DOI: 10.1242/Dev.150516  0.38
2017 Bellono NW, Bayrer JR, Leitch DB, Castro J, Zhang C, O'Donnell TA, Brierley SM, Ingraham HA, Julius D. Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways. Cell. PMID 28648659 DOI: 10.1016/J.Cell.2017.05.034  0.325
2016 de Jesus Cortez F, Suzawa M, Irvy S, Bruning JM, Sablin E, Jacobson MP, Fletterick RJ, Ingraham HA, England PM. Disulfide-Trapping Identifies a New, Effective Chemical Probe for Activating the Nuclear Receptor Human LRH-1 (NR5A2). Plos One. 11: e0159316. PMID 27467220 DOI: 10.1371/Journal.Pone.0159316  0.599
2015 Suzawa M, Miranda DA, Ramos KA, Ang KK, Faivre EJ, Wilson CG, Caboni L, Arkin MR, Kim YS, Fletterick RJ, Diaz A, Schneekloth JS, Ingraham HA. A gene-expression screen identifies a non-toxic sumoylation inhibitor that Mimics SUMO-less human LRH-1 in liver. Elife. 4. PMID 26653140 DOI: 10.7554/Elife.09003  0.556
2015 Sablin EP, Blind RD, Uthayaruban R, Chiu HJ, Deacon AM, Das D, Ingraham HA, Fletterick RJ. Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket. Journal of Structural Biology. PMID 26416531 DOI: 10.1016/J.Jsb.2015.09.012  0.792
2015 Correa SM, Newstrom DW, Warne JP, Flandin P, Cheung CC, Lin-Moore AT, Pierce AA, Xu AW, Rubenstein JL, Ingraham HA. An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females. Cell Reports. 10: 62-74. PMID 25543145 DOI: 10.1016/J.Celrep.2014.12.011  0.553
2015 Suzawa M, Miranda DA, Ramos KA, Ang KK, Faivre EJ, Wilson CG, Caboni L, Arkin MR, Kim Y, Fletterick RJ, Diaz A, Schneekloth JS, Ingraham HA. Author response: A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver Elife. DOI: 10.7554/Elife.09003.028  0.506
2015 Bayrer JR, Fletterick R, Ingraham H. Tu1824 Targeting Intestinal Stem Cells to Promote Healing in Inflammatory Bowel Disease Gastroenterology. 148: S-911-S-912. DOI: 10.1016/S0016-5085(15)33094-8  0.476
2014 Blind RD, Sablin EP, Kuchenbecker KM, Chiu HJ, Deacon AM, Das D, Fletterick RJ, Ingraham HA. The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1. Proceedings of the National Academy of Sciences of the United States of America. 111: 15054-9. PMID 25288771 DOI: 10.1073/Pnas.1416740111  0.789
2013 Ziv L, Muto A, Schoonheim PJ, Meijsing SH, Strasser D, Ingraham HA, Schaaf MJ, Yamamoto KR, Baier H. An affective disorder in zebrafish with mutation of the glucocorticoid receptor. Molecular Psychiatry. 18: 681-91. PMID 22641177 DOI: 10.1038/Mp.2012.64  0.394
2012 Blind RD, Suzawa M, Ingraham HA. Direct modification and activation of a nuclear receptor-PIP₂ complex by the inositol lipid kinase IPMK. Science Signaling. 5: ra44. PMID 22715467 DOI: 10.1126/Scisignal.2003111  0.741
2012 Ingraham HA, Blind RD, VanHook AM. Science Signaling Podcast: 19 June 2012 Science Signaling. 5. DOI: 10.1126/Scisignal.2003287  0.765
2011 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA. Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Developmental Cell. 21: 315-27. PMID 21820362 DOI: 10.1016/J.Devcel.2011.06.028  0.774
2011 Whitby RJ, Stec J, Blind RD, Dixon S, Leesnitzer LM, Orband-Miller LA, Williams SP, Willson TM, Xu R, Zuercher WJ, Cai F, Ingraham HA. Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2). Journal of Medicinal Chemistry. 54: 2266-81. PMID 21391689 DOI: 10.1021/Jm1014296  0.752
2010 Blackshaw S, Scholpp S, Placzek M, Ingraham H, Simerly R, Shimogori T. Molecular pathways controlling development of thalamus and hypothalamus: from neural specification to circuit formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14925-30. PMID 21068293 DOI: 10.1523/Jneurosci.4499-10.2010  0.339
2010 Mullaney BC, Blind RD, Lemieux GA, Perez CL, Elle IC, Faergeman NJ, Van Gilst MR, Ingraham HA, Ashrafi K. Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25. Cell Metabolism. 12: 398-410. PMID 20889131 DOI: 10.1016/J.Cmet.2010.08.013  0.748
2009 Lin BC, Suzawa M, Blind RD, Tobias SC, Bulun SE, Scanlan TS, Ingraham HA. Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation Cancer Research. 69: 5415-5423. PMID 19549922 DOI: 10.1158/0008-5472.Can-08-1622  0.793
2009 Kurrasch DM, Nevin LM, Wong JS, Baier H, Ingraham HA. Neuroendocrine transcriptional programs adapt dynamically to the supply and demand for neuropeptides as revealed in NSF mutant zebrafish. Neural Development. 4: 22. PMID 19549326 DOI: 10.1186/1749-8104-4-22  0.329
2009 Sablin EP, Blind RD, Krylova IN, Ingraham JG, Cai F, Williams JD, Fletterick RJ, Ingraham HA. Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands. Molecular Endocrinology (Baltimore, Md.). 23: 25-34. PMID 18988706 DOI: 10.1210/Me.2007-0508  0.77
2008 Sablin EP, Woods A, Krylova IN, Hwang P, Ingraham HA, Fletterick RJ. The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1. Proceedings of the National Academy of Sciences of the United States of America. 105: 18390-5. PMID 19015525 DOI: 10.1073/Pnas.0808936105  0.607
2008 Campbell LA, Faivre EJ, Show MD, Ingraham JG, Flinders J, Gross JD, Ingraham HA. Decreased recognition of SUMO-sensitive target genes following modification of SF-1 (NR5A1). Molecular and Cellular Biology. 28: 7476-86. PMID 18838537 DOI: 10.1128/Mcb.00103-08  0.655
2008 Suzawa M, Ingraham HA. The herbicide atrazine activates endocrine gene networks via non-steroidal NR5A nuclear receptors in fish and mammalian cells. Plos One. 3: e2117. PMID 18461179 DOI: 10.1371/Journal.Pone.0002117  0.467
2007 Kurrasch DM, Cheung CC, Lee FY, Tran PV, Hata K, Ingraham HA. The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13624-34. PMID 18077674 DOI: 10.1523/Jneurosci.2858-07.2007  0.366
2006 Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, Muscat G, Perlmann T, Renaud JP, Schwabe J, Sladek F, Tsai MJ, Laudet V. International union of pharmacology. LXVI. Orphan nuclear receptors Pharmacological Reviews. 58: 798-836. PMID 17132856 DOI: 10.1124/Pr.58.4.10  0.413
2006 Tran PV, Akana SF, Malkovska I, Dallman MF, Parada LF, Ingraham HA. Diminished hypothalamic bdnf expression and impaired VMH function are associated with reduced SF-1 gene dosage. The Journal of Comparative Neurology. 498: 637-48. PMID 16917842 DOI: 10.1002/Cne.21070  0.333
2005 Ingraham HA, Redinbo MR. Orphan nuclear receptors adopted by crystallography. Current Opinion in Structural Biology. 15: 708-15. PMID 16263271 DOI: 10.1016/J.Sbi.2005.10.009  0.431
2005 Lee MB, Lebedeva LA, Suzawa M, Wadekar SA, Desclozeaux M, Ingraham HA. The DEAD-box protein DP103 (Ddx20 or Gemin-3) represses orphan nuclear receptor activity via SUMO modification. Molecular and Cellular Biology. 25: 1879-90. PMID 15713642 DOI: 10.1128/Mcb.25.5.1879-1890.2005  0.426
2005 Krylova IN, Sablin EP, Moore J, Xu RX, Waitt GM, MacKay JA, Juzumiene D, Bynum JM, Madauss K, Montana V, Lebedeva L, Suzawa M, Williams JD, Williams SP, Guy RK, ... ... Ingraham HA, et al. Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. Cell. 120: 343-55. PMID 15707893 DOI: 10.1016/J.Cell.2005.01.024  0.631
2004 Bland ML, Fowkes RC, Ingraham HA. Differential requirement for steroidogenic factor-1 gene dosage in adrenal development versus endocrine function. Molecular Endocrinology (Baltimore, Md.). 18: 941-52. PMID 14726490 DOI: 10.1210/Me.2003-0333  0.751
2003 Jordan BK, Shen JH, Olaso R, Ingraham HA, Vilain E. Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy. Proceedings of the National Academy of Sciences of the United States of America. 100: 10866-71. PMID 12949260 DOI: 10.1073/Pnas.1834480100  0.34
2003 Fowkes RC, Desclozeaux M, Patel MV, Aylwin SJ, King P, Ingraham HA, Burrin JM. Steroidogenic factor-1 and the gonadotrope-specific element enhance basal and pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein hormone alpha-subunit gene in gonadotropes. Molecular Endocrinology (Baltimore, Md.). 17: 2177-88. PMID 12920232 DOI: 10.1210/Me.2002-0393  0.409
2003 Sablin EP, Krylova IN, Fletterick RJ, Ingraham HA. Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1. Molecular Cell. 11: 1575-85. PMID 12820970 DOI: 10.1016/S1097-2765(03)00236-3  0.608
2003 Bland ML, Desclozeaux M, Ingraham HA. Tissue growth and remodeling of the embryonic and adult adrenal gland. Annals of the New York Academy of Sciences. 995: 59-72. PMID 12814939 DOI: 10.1111/J.1749-6632.2003.Tb03210.X  0.734
2003 Tran PV, Lee MB, Marín O, Xu B, Jones KR, Reichardt LF, Rubenstein JR, Ingraham HA. Requirement of the orphan nuclear receptor SF-1 in terminal differentiation of ventromedial hypothalamic neurons. Molecular and Cellular Neurosciences. 22: 441-53. PMID 12727442 DOI: 10.1016/S1044-7431(03)00027-7  0.384
2003 Huber BR, Desclozeaux M, West BL, Cunha-Lima ST, Nguyen HT, Baxter JD, Ingraham HA, Fletterick RJ. Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain. Molecular Endocrinology (Baltimore, Md.). 17: 107-16. PMID 12511610 DOI: 10.1210/Me.2002-0097  0.574
2002 Desclozeaux M, Krylova IN, Horn F, Fletterick RJ, Ingraham HA. Phosphorylation and intramolecular stabilization of the ligand binding domain in the nuclear receptor steroidogenic factor 1. Molecular and Cellular Biology. 22: 7193-203. PMID 12242296 DOI: 10.1128/Mcb.22.20.7193-7203.2002  0.601
2002 Roberts LM, Visser JA, Ingraham HA. Involvement of a matrix metalloproteinase in MIS-induced cell death during urogenital development. Development (Cambridge, England). 129: 1487-96. PMID 11880357  0.547
2002 Shen JH, Ingraham HA. Regulation of the orphan nuclear receptor steroidogenic factor 1 by Sox proteins. Molecular Endocrinology (Baltimore, Md.). 16: 529-40. PMID 11875113 DOI: 10.1210/Mend.16.3.0782  0.409
2002 Durlinger AL, Gruijters MJ, Kramer P, Karels B, Ingraham HA, Nachtigal MW, Uilenbroek JT, Grootegoed JA, Themmen AP. Anti-Müllerian hormone inhibits initiation of primordial follicle growth in the mouse ovary. Endocrinology. 143: 1076-84. PMID 11861535 DOI: 10.1210/Endo.143.3.8691  0.335
2001 Visser JA, Olaso R, Verhoef-Post M, Kramer P, Themmen AP, Ingraham HA. The serine/threonine transmembrane receptor ALK2 mediates Müllerian inhibiting substance signaling. Molecular Endocrinology (Baltimore, Md.). 15: 936-45. PMID 11376112 DOI: 10.1210/Mend.15.6.0645  0.408
2001 McGee EA, Smith R, Spears N, Nachtigal MW, Ingraham H, Hsueh AJ. Müllerian inhibitory substance induces growth of rat preantral ovarian follicles. Biology of Reproduction. 64: 293-8. PMID 11133686 DOI: 10.1095/Biolreprod64.1.293  0.34
2000 Bland ML, Jamieson C, Akana S, Dallman M, Ingraham HA. Gene dosage effects of steroidogenic factor 1 (SF-1) in adrenal development and the stress. Endocrine Research. 26: 515-6. PMID 11196422 DOI: 10.3109/07435800009048563  0.712
2000 Bland ML, Jamieson CA, Akana SF, Bornstein SR, Eisenhofer G, Dallman MF, Ingraham HA. Haploinsufficiency of steroidogenic factor-1 in mice disrupts adrenal development leading to an impaired stress response. Proceedings of the National Academy of Sciences of the United States of America. 97: 14488-93. PMID 11121051 DOI: 10.1073/Pnas.97.26.14488  0.736
2000 Ingraham HA, Hirokawa Y, Roberts LM, Mellon SH, McGee E, Nachtigal MW, Visser JA. Autocrine and paracrine Müllerian inhibiting substance hormone signaling in reproduction. Recent Progress in Hormone Research. 55: 53-67; discussion 67. PMID 11036933  0.609
1999 Roberts LM, Shen J, Ingraham HA. New solutions to an ancient riddle: defining the differences between Adam and Eve. American Journal of Human Genetics. 65: 933-42. PMID 10486311 DOI: 10.1086/302601  0.592
1999 Hammer GD, Ingraham HA. Steroidogenic factor-1: its role in endocrine organ development and differentiation. Frontiers in Neuroendocrinology. 20: 199-223. PMID 10433862 DOI: 10.1006/Frne.1999.0182  0.48
1999 Hammer GD, Krylova I, Zhang Y, Darimont BD, Simpson K, Weigel NL, Ingraham HA. Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress. Molecular Cell. 3: 521-6. PMID 10230405 DOI: 10.1016/S1097-2765(00)80480-3  0.445
1999 Roberts LM, Hirokawa Y, Nachtigal MW, Ingraham HA. Paracrine-mediated apoptosis in reproductive tract development. Developmental Biology. 208: 110-22. PMID 10075845 DOI: 10.1006/Dbio.1998.9190  0.592
1998 Bedford FK, Julius D, Ingraham HA. Neuronal expression of the 5HT3 serotonin receptor gene requires nuclear factor 1 complexes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6186-94. PMID 9698312 DOI: 10.1523/Jneurosci.18-16-06186.1998  0.375
1998 Nachtigal MW, Hirokawa Y, Enyeart-VanHouten DL, Flanagan JN, Hammer GD, Ingraham HA. Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression. Cell. 93: 445-54. PMID 9590178 DOI: 10.1016/S0092-8674(00)81172-1  0.365
1996 Bedford FK, Christopherson K, Nachtigal MW, Shen WH, Julius DJ, Ingraham HA. Molecular biology of pituitary development and disease. Hormone Research. 45: 19-21. PMID 8805023 DOI: 10.1159/000184822  0.381
1996 Nachtigal MW, Ingraham HA. Bioactivation of Müllerian inhibiting substance during gonadal development by a kex2/subtilisin-like endoprotease. Proceedings of the National Academy of Sciences of the United States of America. 93: 7711-6. PMID 8755541 DOI: 10.1073/Pnas.93.15.7711  0.334
1994 Shen WH, Moore CC, Ikeda Y, Parker KL, Ingraham HA. Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: a link to the sex determination cascade. Cell. 77: 651-61. PMID 8205615 DOI: 10.1016/0092-8674(94)90050-7  0.467
1994 Ikeda Y, Shen WH, Ingraham HA, Parker KL. Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Molecular Endocrinology (Baltimore, Md.). 8: 654-62. PMID 8058073 DOI: 10.1210/Mend.8.5.8058073  0.356
1994 Ingraham HA, Lala DS, Ikeda Y, Luo X, Shen WH, Nachtigal MW, Abbud R, Nilson JH, Parker KL. The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis. Genes & Development. 8: 2302-12. PMID 7958897 DOI: 10.1101/Gad.8.19.2302  0.394
1992 Pfäffle RW, DiMattia GE, Parks JS, Brown MR, Wit JM, Jansen M, Van der Nat H, Van den Brande JL, Rosenfeld MG, Ingraham HA. Mutation of the POU-specific domain of Pit-1 and hypopituitarism without pituitary hypoplasia. Science (New York, N.Y.). 257: 1118-21. PMID 1509263 DOI: 10.1126/Science.257.5073.1118  0.364
1991 Carpenter CD, Ingraham HA, Cochet C, Walton GM, Lazar CS, Sowadski JM, Rosenfeld MG, Gill GN. Structural analysis of the transmembrane domain of the epidermal growth factor receptor. The Journal of Biological Chemistry. 266: 5750-5. PMID 2005111  0.3
1990 Simmons DM, Voss JW, Ingraham HA, Holloway JM, Broide RS, Rosenfeld MG, Swanson LW. Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors. Genes & Development. 4: 695-711. PMID 2379827 DOI: 10.1101/Gad.4.5.695  0.422
1990 Ingraham HA, Flynn SE, Voss JW, Albert VR, Kapiloff MS, Wilson L, Rosenfeld MG. The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell. 61: 1021-33. PMID 2350782 DOI: 10.1016/0092-8674(90)90067-O  0.326
1990 Ingraham HA, Albert VR, Chen RP, Crenshaw 3d EB, Elsholtz HP, He X, Kapiloff MS, Mangalam HJ, Swanson LW, Treacy MN. A family of POU-domain and Pit-1 tissue-specific transcription factors in pituitary and neuroendocrine development. Annual Review of Physiology. 52: 773-91. PMID 2184776 DOI: 10.1146/Annurev.Ph.52.030190.004013  0.408
1990 Chen RP, Ingraham HA, Treacy MN, Albert VR, Wilson L, Rosenfeld MG. Autoregulation of pit-1 gene expression mediated by two cis-active promoter elements. Nature. 346: 583-6. PMID 2142999 DOI: 10.1038/346583A0  0.394
1990 Heisermann GJ, Wiley HS, Walsh BJ, Ingraham HA, Fiol CJ, Gill GN. Mutational removal of the Thr669 and Ser671 phosphorylation sites alters substrate specificity and ligand-induced internalization of the epidermal growth factor receptor. The Journal of Biological Chemistry. 265: 12820-7. PMID 2115882  0.305
1989 He X, Treacy MN, Simmons DM, Ingraham HA, Swanson LW, Rosenfeld MG. Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature. 340: 35-41. PMID 2739723 DOI: 10.1038/340035A0  0.319
1989 Mangalam HJ, Albert VR, Ingraham HA, Kapiloff M, Wilson L, Nelson C, Elsholtz H, Rosenfeld MG. A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally. Genes & Development. 3: 946-58. PMID 2550324 DOI: 10.1101/Gad.3.7.946  0.408
1988 Gill GN, Chen WS, Lazar CS, Glenney JR, Wiley HS, Ingraham HA, Rosenfeld MG. Role of intrinsic protein tyrosine kinase in function and metabolism of the epidermal growth factor receptor. Cold Spring Harbor Symposia On Quantitative Biology. 53: 467-76. PMID 3254778 DOI: 10.1101/Sqb.1988.053.01.054  0.342
1988 Herr W, Sturm RA, Clerc RG, Corcoran LM, Baltimore D, Sharp PA, Ingraham HA, Rosenfeld MG, Finney M, Ruvkun G. The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes & Development. 2: 1513-6. PMID 3215510 DOI: 10.1101/Gad.2.12A.1513  0.307
1988 Ingraham HA, Chen RP, Mangalam HJ, Elsholtz HP, Flynn SE, Lin CR, Simmons DM, Swanson L, Rosenfeld MG. A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype. Cell. 55: 519-29. PMID 2902928 DOI: 10.1016/0092-8674(88)90038-4  0.408
1986 Ingraham HA, Dickey L, Goulian M. DNA fragmentation and cytotoxicity from increased cellular deoxyuridylate. Biochemistry. 25: 3225-30. PMID 3524674 DOI: 10.1021/Bi00359A022  0.583
1986 Goulian M, Bleile BM, Dickey LM, Grafstrom RH, Ingraham HA, Neynaber SA, Peterson MS, Tseng BY. Mechanism of thymineless death. Advances in Experimental Medicine and Biology. 195: 89-95. PMID 3020930 DOI: 10.1007/978-1-4684-1248-2_15  0.547
1986 Ingraham HA, Evans GA. Characterization of two atypical promoters and alternate mRNA processing in the mouse Thy-1.2 glycoprotein gene. Molecular and Cellular Biology. 6: 2923-31. PMID 2878365 DOI: 10.1128/Mcb.6.8.2923  0.332
1985 Goulian M, Ingraham H, Tseng B, Dickey L, Bleile B, Neynaber S. MECHANISM OF THYMINELESS DEATH: 73 Pediatric Research. 19: 756-756. DOI: 10.1203/00006450-198507000-00093  0.566
1984 Evans GA, Ingraham HA, Lewis K, Cunningham K, Seki T, Moriuchi T, Chang HC, Silver J, Hyman R. Expression of the Thy-1 glycoprotein gene by DNA-mediated gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 81: 5532-6. PMID 6147849 DOI: 10.1073/Pnas.81.17.5532  0.322
1983 Peterson MS, Ingraham HA, Goulian M. 2'-deoxyribosyl analogues of UDP-N-acetylglucosamine in cells treated with methotrexate or 5-fluorodeoxyuridine. The Journal of Biological Chemistry. 258: 10831-4. PMID 6224793  0.551
1983 Patrick J, Ballivet M, Boas L, Claudio T, Forrest J, Ingraham H, Mason P, Stengelin S, Ueno S, Heinemann S. Molecular cloning of the acetylcholine receptor. Cold Spring Harbor Symposia On Quantitative Biology. 48: 71-78. PMID 6202451 DOI: 10.1101/Sqb.1983.048.01.009  0.319
1982 Ingraham HA, Tseng BY, Goulian M. Nucleotide levels and incorporation of 5-fluorouracil and uracil into DNA of cells treated with 5-fluorodeoxyuridine. Molecular Pharmacology. 21: 211-6. PMID 6215571  0.524
1982 Ingraham HA, Goulian M. Deoxyuridine triphosphatase: a potential site of interaction with pyrimidine nucleotide analogues. Biochemical and Biophysical Research Communications. 109: 746-52. PMID 6130763 DOI: 10.1016/0006-291X(82)92003-4  0.549
1980 Ingraham HA, Tseng BY, Goulian M. Mechanism for exclusion of 5-fluorouracil from DNA. Cancer Research. 40: 998-1001. PMID 6101994  0.503
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