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Ani W. Manichaikul - Publications

Affiliations: 
2008 Biostatistics Johns Hopkins University, Baltimore, MD 
 2008-2009 Biomedical Engineering University of Virginia, Charlottesville, VA 
 2009- Public Health Sciences University of Virginia, Charlottesville, VA 
Website:
http://people.virginia.edu/~am3xa/
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104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, ... ... Manichaikul A, et al. A saturated map of common genetic variants associated with human height. Nature. PMID 36224396 DOI: 10.1038/s41586-022-05275-y  0.324
2021 Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, ... ... Manichaikul A, et al. The power of genetic diversity in genome-wide association studies of lipids. Nature. PMID 34887591 DOI: 10.1038/s41586-021-04064-3  0.304
2021 Katz DH, Tahir UA, Bick AG, Pampana A, Ngo D, Benson MD, Yu Z, Robbins JM, Chen ZZ, Cruz DE, Deng S, Farrell L, Sinha S, Schmaier AA, Shen D, ... ... Manichaikul AW, et al. Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights into Cardiovascular Disease. Circulation. PMID 34814699 DOI: 10.1161/CIRCULATIONAHA.121.055117  0.309
2021 Mikhaylova AV, McHugh CP, Polfus LM, Raffield LM, Boorgula MP, Blackwell TW, Brody JA, Broome J, Chami N, Chen MH, Conomos MP, Cox C, Curran JE, Daya M, Ekunwe L, ... ... Manichaikul A, et al. Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program. American Journal of Human Genetics. PMID 34582791 DOI: 10.1016/j.ajhg.2021.08.007  0.311
2021 Yang C, Hallmark B, Chai JC, O'Connor TD, Reynolds LM, Wood AC, Seeds M, Chen YI, Steffen LM, Tsai MY, Kaplan RC, Daviglus ML, Mandarino LJ, Fretts AM, Lemaitre RN, ... ... Manichaikul A, et al. Impact of Amerind ancestry and FADS genetic variation on omega-3 deficiency and cardiometabolic traits in Hispanic populations. Communications Biology. 4: 918. PMID 34321601 DOI: 10.1038/s42003-021-02431-4  0.319
2020 Aherrahrou R, Guo L, Nagraj VP, Aguhob AA, Hinkle J, Chen L, Soh JY, Lue D, Alencar GF, Boltjes A, van der Laan SW, Farber E, Fuller D, Anane-Wae R, Akingbesote ND, ... Manichaikul AW, et al. Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells. Circulation Research. PMID 33040646 DOI: 10.1161/CIRCRESAHA.120.317415  0.323
2020 Bootpetch TC, Hafrén L, Elling CL, Baschal EE, Manichaikul AW, Pine HS, Szeremeta W, Scholes MA, Cass SP, Larson ED, Chan KH, Ishaq R, Prager JD, Shaikh RS, Gubbels SP, et al. Multi-omic studies on missense PLG variants in families with otitis media. Scientific Reports. 10: 15035. PMID 32929111 DOI: 10.1038/S41598-020-70498-W  0.308
2020 Vuckovic D, Bao EL, Akbari P, Lareau CA, Mousas A, Jiang T, Chen MH, Raffield LM, Tardaguila M, Huffman JE, Ritchie SC, Megy K, Ponstingl H, Penkett CJ, Albers PK, ... ... Manichaikul A, et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell. 182: 1214-1231.e11. PMID 32888494 DOI: 10.1016/J.Cell.2020.08.008  0.363
2020 Chen MH, Raffield LM, Mousas A, Sakaue S, Huffman JE, Moscati A, Trivedi B, Jiang T, Akbari P, Vuckovic D, Bao EL, Zhong X, Manansala R, Laplante V, Chen M, ... ... Manichaikul A, et al. Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Cell. 182: 1198-1213.e14. PMID 32888493 DOI: 10.1016/J.Cell.2020.06.045  0.392
2020 Li X, Li Z, Zhou H, Gaynor SM, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Aslibekyan S, Ballantyne CM, Bielak LF, Blangero J, Boerwinkle E, Bowden DW, ... ... Manichaikul AW, et al. Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nature Genetics. PMID 32839606 DOI: 10.1038/S41588-020-0676-4  0.395
2020 Moll M, Sakornsakolpat P, Shrine N, Hobbs BD, DeMeo DL, John C, Guyatt AL, McGeachie MJ, Gharib SA, Obeidat M, Lahousse L, Wijnant SRA, Brusselle G, Meyers DA, Bleecker ER, ... ... Manichaikul A, et al. Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts. The Lancet. Respiratory Medicine. 8: 696-708. PMID 32649918 DOI: 10.1016/S2213-2600(20)30101-6  0.335
2020 Fuller DT, Grainger AT, Manichaikul A, Shi W. Data on genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from hyperlipidemic mouse strains. Data in Brief. 29: 105165. PMID 32025547 DOI: 10.1016/J.Dib.2020.105165  0.333
2020 Fuller DT, Grainger AT, Manichaikul A, Shi W. Genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from hyperlipidemic mouse strains. Atherosclerosis. 293: 1-10. PMID 31821957 DOI: 10.1016/J.Atherosclerosis.2019.11.034  0.334
2019 Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, Deelen P, Rohde R, Schurmann C, Guo X, Giulianini F, ... ... Manichaikul AW, et al. Associations of autozygosity with a broad range of human phenotypes. Nature Communications. 10: 4957. PMID 31673082 DOI: 10.1038/S41467-019-12283-6  0.325
2019 Aung N, Vargas JD, Yang C, Cabrera CP, Warren HR, Fung K, Tzanis E, Barnes MR, Rotter JI, Taylor KD, Manichaikul AW, Lima JAC, Bluemke DA, Piechnik SK, Neubauer S, et al. Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated with Cardiac Morphogenesis and Heart Failure Development. Circulation. PMID 31554410 DOI: 10.1161/Circulationaha.119.041161  0.361
2019 Hobbs BD, Putman RK, Araki T, Nishino M, Gudmundsson G, Gudnason V, Eiriksdottir G, Zilhao Nogueira NR, Dupuis J, Xu H, O'Connor GT, Manichaikul A, Nguyen J, Podolanczuk AJ, Madahar P, et al. Overlap of Genetic Risk Between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 31339356 DOI: 10.1164/Rccm.201903-0511Oc  0.418
2019 Grant DJ, Manichaikul A, Alberg AJ, Bandera EV, Barnholtz-Sloan J, Bondy M, Cote ML, Funkhouser E, Moorman PG, Peres LC, Peters ES, Schwartz AG, Terry PD, Wang XQ, Keku TO, et al. Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women. Cancer Medicine. PMID 31001917 DOI: 10.1002/Cam4.1996  0.387
2019 Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo X, Liu J, Lu Y, Cheng CY, Sim X, ... ... Manichaikul AW, et al. Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics. 51: 636-648. PMID 30926973 DOI: 10.1038/S41588-019-0378-Y  0.353
2019 Oelsner EC, Ortega VE, Smith BM, Nguyen JN, Manichaikul AW, Hoffman EA, Guo X, Taylor KD, Woodruff PG, Couper DJ, Hansel NN, Martinez FJ, Paine Iii R, Han MK, Cooper C, et al. A Genetic Risk Score Associated with COPD Susceptibility and Lung Structure on Computed Tomography. American Journal of Respiratory and Critical Care Medicine. PMID 30925230 DOI: 10.1164/Rccm.201812-2355Oc  0.347
2019 de Vries PS, Brown MR, Bentley AR, Sung YJ, Winkler TW, Ntalla I, Schwander K, Kraja AT, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, ... ... Manichaikul AW, et al. Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. American Journal of Epidemiology. PMID 30698716 DOI: 10.1093/Aje/Kwz005  0.361
2019 Kilpeläinen TO, Bentley AR, Noordam R, Sung YJ, Schwander K, Winkler TW, Jakupović H, Chasman DI, Manning A, Ntalla I, Aschard H, Brown MR, de Las Fuentes L, Franceschini N, Guo X, ... ... Manichaikul A, et al. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nature Communications. 10: 376. PMID 30670697 DOI: 10.1038/S41467-018-08008-W  0.333
2019 Aung N, Vargas JD, Manichaikul AW, Yang C, Cabrera CP, Warren HR, Fung K, Tzanis E, Barnes MR, Bluemke DA, Piechnik SK, Neubauer S, Munroe PB, Petersen SE. 199Genetic architecture of left ventricular phenotypes derived from 17,000 CMR studies in the UK Biobank population imaging cohort European Journal of Echocardiography. 20. DOI: 10.1093/Ehjci/Jez128  0.306
2018 Manichaikul A, Wang XQ, Li L, Erdmann J, Lettre G, Bis JC, Waterworth D, Cushman M, Jenny NS, Post WS, Palmas W, Tsai MY, Wallentin L, White H, Schunkert H, et al. Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease. Plos One. 13: e0204352. PMID 30289950 DOI: 10.1371/Journal.Pone.0204352  0.323
2018 Merino J, Dashti HS, Li SX, Sarnowski C, Justice AE, Graff M, Papoutsakis C, Smith CE, Dedoussis GV, Lemaitre RN, Wojczynski MK, Männistö S, Ngwa JS, Kho M, Ahluwalia TS, ... ... Manichaikul A, et al. Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. Molecular Psychiatry. PMID 29988085 DOI: 10.1038/S41380-018-0079-4  0.308
2018 Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, et al. Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nature Communications. 9: 2606. PMID 29973585 DOI: 10.1038/S41467-018-04668-W  0.375
2018 Prokopenko D, Sakornsakolpat P, Loehlein Fier H, Qiao D, Parker MM, McDonald MN, Manichaikul A, Rich SS, Barr RG, Williams CJ, Brantly ML, Lange C, Beaty TH, Crapo JD, Silverman EK, et al. Whole Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease. American Journal of Respiratory Cell and Molecular Biology. PMID 29949718 DOI: 10.1165/Rcmb.2018-0088Oc  0.344
2018 de Oliveira Otto MC, Lemaitre RN, Sun Q, King IB, Wu JHY, Manichaikul A, Rich SS, Tsai MY, Chen YD, Fornage M, Weihua G, Aslibekyan S, Irvin MR, Kabagambe EK, Arnett DK, et al. Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium. Plos One. 13: e0196951. PMID 29738550 DOI: 10.1371/Journal.Pone.0196951  0.323
2018 Sakornsakolpat P, Morrow JD, Castaldi PJ, Hersh CP, Bossé Y, Silverman EK, Manichaikul A, Cho MH. Integrative genomics identifies new genes associated with severe COPD and emphysema. Respiratory Research. 19: 46. PMID 29566699 DOI: 10.1186/S12931-018-0744-9  0.376
2018 Oelsner E, Smith B, Nguyen J, Manichaikul A, Hoffman E, Ampleford E, Dimitrov L, Guo X, Taylor K, Bleecker E, Li X, Meyers D, Peters S, Rich S, Rotter J, et al. Late Breaking Abstract - Associations between a COPD genetic risk score and lung structure on computed tomography (CT): SPIROMICS European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Oa2187  0.336
2017 Mozaffarian D, Dashti HS, Wojczynski MK, Chu AY, Nettleton JA, Männistö S, Kristiansson K, Reedik M, Lahti J, Houston DK, Cornelis MC, van Rooij FJA, Dimitriou M, Kanoni S, Mikkilä V, ... ... Manichaikul A, et al. Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts. Plos One. 12: e0186456. PMID 29236708 DOI: 10.1371/Journal.Pone.0186456  0.349
2017 Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, ... ... Manichaikul A, et al. Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics. PMID 29083408 DOI: 10.1038/Ng.3977  0.324
2017 Manichaikul A, Wang XQ, Sun L, Dupuis J, Borczuk AC, Nguyen JN, Raghu G, Hoffman EA, Onengut-Gumuscu S, Farber EA, Kaufman JD, Rabinowitz D, Stukovsky KDH, Kawut SM, Hunninghake GM, et al. Genome-wide association study of subclinical interstitial lung disease in MESA. Respiratory Research. 18: 97. PMID 28521775 DOI: 10.1186/S12931-017-0581-2  0.345
2017 Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D, Ngwa JS, Ahluwalia TS, Chu AY, Heard-Costa NL, Lim E, ... ... Manichaikul A, et al. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications. 8: 14977. PMID 28443625 DOI: 10.1038/Ncomms14977  0.367
2017 Hu Y, Tanaka T, Zhu J, Guan W, Wu JH, Psaty BM, McKnight B, King IB, Sun Q, Richard M, Manichaikul A, Frazier-Wood AC, Kabagambe EK, Hopkins PN, Ordovas JM, et al. Discovery and fine-mapping of loci associated with monounsaturated fatty acids through trans-ethnic meta-analysis in Chinese and European populations. Journal of Lipid Research. PMID 28298293 DOI: 10.1194/Jlr.P071860  0.399
2017 Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, ... ... Manichaikul A, et al. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nature Genetics. PMID 28166215 DOI: 10.1038/Ng.3752  0.39
2017 Aschard H, Tobin MD, Hancock DB, Skurnik D, Sood A, James A, Vernon Smith A, Manichaikul AW, Campbell A, Prins BP, Hayward C, Loth DW, Porteous DJ, Strachan DP, Zeggini E, et al. Evidence for large-scale gene-by-smoking interaction effects on pulmonary function. International Journal of Epidemiology. PMID 28082375 DOI: 10.1093/Ije/Dyw318  0.315
2016 Zubair N, Graff M, Luis Ambite J, Bush WS, Kichaev G, Lu Y, Manichaikul A, Sheu WH, Absher D, Assimes TL, Bielinski SJ, Bottinger EP, Buzkova P, Chuang LM, Chung RH, et al. Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci. Human Molecular Genetics. 25: 5500-5512. PMID 28426890 DOI: 10.1093/Hmg/Ddw358  0.363
2016 Golden D, Kolmakova A, Sura S, Vella AT, Manichaikul A, Wang XQ, Bielinski SJ, Taylor KD, Chen YI, Rich SS, Rodriguez A. Lymphocyte activation gene 3 and coronary artery disease. Jci Insight. 1: e88628. PMID 27777974 DOI: 10.1172/Jci.Insight.88628  0.308
2016 Franceschini N, Carty CL, Lu Y, Tao R, Sung YJ, Manichaikul A, Haessler J, Fornage M, Schwander K, Zubair N, Bien S, Hindorff LA, Guo X, Bielinski SJ, Ehret G, et al. Variant Discovery and Fine Mapping of Genetic Loci Associated with Blood Pressure Traits in Hispanics and African Americans. Plos One. 11: e0164132. PMID 27736895 DOI: 10.1371/Journal.Pone.0164132  0.34
2016 Grainger AT, Jones MB, Li J, Chen MH, Manichaikul A, Shi W. Genetic analysis of atherosclerosis identifies a major susceptibility locus in the major histocompatibility complex of mice. Atherosclerosis. 254: 124-132. PMID 27736672 DOI: 10.1016/J.Atherosclerosis.2016.10.011  0.398
2016 Tajuddin SM, Schick UM, Eicher JD, Chami N, Giri A, Brody JA, Hill WD, Kacprowski T, Li J, Lyytikäinen LP, Manichaikul A, Mihailov E, O'Donoghue ML, Pankratz N, Pazoki R, et al. Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. American Journal of Human Genetics. PMID 27346689 DOI: 10.1016/J.Ajhg.2016.05.003  0.373
2016 Eicher JD, Chami N, Kacprowski T, Nomura A, Chen MH, Yanek LR, Tajuddin SM, Schick UM, Slater AJ, Pankratz N, Polfus L, Schurmann C, Giri A, Brody JA, Lange LA, ... Manichaikul A, et al. Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. American Journal of Human Genetics. PMID 27346686 DOI: 10.1016/J.Ajhg.2016.05.005  0.347
2016 Chami N, Chen MH, Slater AJ, Eicher JD, Evangelou E, Tajuddin SM, Love-Gregory L, Kacprowski T, Schick UM, Nomura A, Giri A, Lessard S, Brody JA, Schurmann C, Pankratz N, ... ... Manichaikul A, et al. Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. American Journal of Human Genetics. PMID 27346685 DOI: 10.1016/J.Ajhg.2016.05.007  0.41
2016 Manichaikul A, Rich SS, Allison MA, Guagliardo NA, Bayliss DA, Carey RM, Barrett PQ. KCNK3 Variants Are Associated With Hyperaldosteronism and Hypertension. Hypertension. PMID 27296998 DOI: 10.1161/Hypertensionaha.116.07564  0.387
2016 van Leeuwen EM, Sabo A, Bis JC, Huffman JE, Manichaikul A, Smith AV, Feitosa MF, Demissie S, Joshi PK, Duan Q, Marten J, van Klinken JB, Surakka I, Nolte IM, Zhang W, et al. Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. Journal of Medical Genetics. PMID 27036123 DOI: 10.1136/Jmedgenet-2015-103439  0.397
2016 Vargas JD, Manichaikul A, Wang XQ, Rich SS, Rotter JI, Post WS, Polak JF, Budoff MJ, Bluemke DA. Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis. Data in Brief. 7: 229-42. PMID 26958643 DOI: 10.1016/J.Dib.2016.01.048  0.39
2016 Zhu J, Manichaikul A, Hu Y, Chen YI, Liang S, Steffen LM, Rich SS, Tsai M, Siscovick DS, Lemaitre RN, Li H, Lin X. Meta-analysis of genome-wide association studies identifies three novel loci for saturated fatty acids in East Asians. European Journal of Nutrition. PMID 26932504 DOI: 10.1007/S00394-016-1193-1  0.374
2016 Ma Y, Follis JL, Smith CE, Tanaka T, Manichaikul AW, Chu AY, Samieri C, Zhou X, Guan W, Wang L, Biggs ML, Chen YI, Hernandez DG, Borecki I, Chasman DI, et al. Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. The American Journal of Clinical Nutrition. PMID 26791180 DOI: 10.3945/Ajcn.115.112987  0.342
2016 Hu Y, Lu L, Manichaikul A, Zhu J, Chen YI, Sun L, Liang S, Siscovick DS, Steffen LM, Tsai MY, Rich SS, Lemaitre RN, Li H, Lin X. Genome-wide meta-analyses identify novel loci associated with n-3 and n-6 polyunsaturated fatty acid levels in Chinese and European-ancestry populations. Human Molecular Genetics. PMID 26744325 DOI: 10.1093/Hmg/Ddw002  0.408
2016 Vargas JD, Manichaikul A, Liu C, Rich S, Post W, Judge D, Bluemke D. COMMON GENETIC VARIANTS AND LEFT VENTRICULAR STRUCTURE IN THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS Journal of the American College of Cardiology. 67: 1835. DOI: 10.1016/S0735-1097(16)31836-8  0.323
2015 Vargas JD, Manichaikul A, Wang XQ, Rich SS, Rotter JI, Post WS, Polak JF, Budoff MJ, Bluemke DA. Common genetic variants and subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 245: 230-236. PMID 26789557 DOI: 10.1016/J.Atherosclerosis.2015.11.034  0.36
2015 Manichaikul A, Wang XQ, Zhao W, Wojczynski MK, Siebenthall K, Stamatoyannopoulos JA, Saleheen D, Borecki IB, Reilly MP, Rich SS, Bornfeldt KE. Genetic association of long-chain acyl-CoA synthetase 1 variants with fasting glucose, diabetes and subclinical atherosclerosis. Journal of Lipid Research. PMID 26711138 DOI: 10.1194/Jlr.M064592  0.362
2015 Ventetuolo CE, Mitra N, Wan F, Manichaikul A, Barr RG, Johnson C, Bluemke DA, Lima JA, Tandri H, Ouyang P, Kawut SM. Oestradiol metabolism and androgen receptor genotypes are associated with right ventricular function. The European Respiratory Journal. PMID 26647441 DOI: 10.1183/13993003.01083-2015  0.384
2015 Wang Q, Grainger AT, Manichaikul A, Farber E, Onengut-Gumuscu S, Shi W. Genetic linkage of hyperglycemia and dyslipidemia in an intercross between BALB/cJ and SM/J Apoe-deficient mouse strains. Bmc Genetics. 16: 133. PMID 26555648 DOI: 10.1186/S12863-015-0292-Y  0.349
2015 Gharib SA, Loth DW, Soler Artigas M, Birkland TP, Wilk JB, Wain LV, Brody J, Obeidat M, Hancock DB, Tang W, Rawal R, Boezen HM, Imboden M, Huffman JE, Lahousse L, ... ... Manichaikul A, et al. Integrative Pathway Genomics of Lung Function and Airflow Obstruction. Human Molecular Genetics. PMID 26395457 DOI: 10.1093/Hmg/Ddv378  0.369
2015 Nettleton JA, Follis JL, Ngwa JS, Smith CE, Ahmad S, Tanaka T, Wojczynski MK, Voortman T, Lemaitre RN, Kristiansson K, Nuotio ML, Houston DK, Perälä MM, Qi Q, Sonestedt E, ... Manichaikul A, et al. Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry. Human Molecular Genetics. 24: 4728-38. PMID 25994509 DOI: 10.1093/Hmg/Ddv186  0.363
2015 Manichaikul A, Wang XQ, Musani SK, Herrington DM, Post WS, Wilson JG, Rich SS, Rodriguez A. Association of the Lipoprotein Receptor SCARB1 Common Missense Variant rs4238001 with Incident Coronary Heart Disease. Plos One. 10: e0125497. PMID 25993026 DOI: 10.1371/Journal.Pone.0125497  0.333
2015 Auer PL, Nalls M, Meschia JF, Worrall BB, Longstreth WT, Seshadri S, Kooperberg C, Burger KM, Carlson CS, Carty CL, Chen WM, Cupples LA, DeStefano AL, Fornage M, Hardy J, ... ... Manichaikul A, et al. Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project. Jama Neurology. 72: 781-8. PMID 25961151 DOI: 10.1001/Jamaneurol.2015.0582  0.305
2015 van Leeuwen EM, Karssen LC, Deelen J, Isaacs A, Medina-Gomez C, Mbarek H, Kanterakis A, Trompet S, Postmus I, Verweij N, van Enckevort DJ, Huffman JE, White CC, Feitosa MF, Bartz TM, ... Manichaikul A, et al. Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nature Communications. 6: 6065. PMID 25751400 DOI: 10.1038/Ncomms7065  0.394
2015 Mozaffarian D, Kabagambe EK, Johnson CO, Lemaitre RN, Manichaikul A, Sun Q, Foy M, Wang L, Wiener H, Irvin MR, Rich SS, Wu H, Jensen MK, Chasman DI, Chu AY, et al. Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. The American Journal of Clinical Nutrition. 101: 398-406. PMID 25646338 DOI: 10.3945/Ajcn.114.094557  0.327
2015 Chen W, Brehm JM, Manichaikul A, Cho MH, Boutaoui N, Yan Q, Burkart KM, Enright PL, Rotter JI, Petersen H, Leng S, Obeidat M, Bossé Y, Brandsma CA, Hao K, et al. A genome-wide association study of chronic obstructive pulmonary disease in Hispanics. Annals of the American Thoracic Society. 12: 340-8. PMID 25584925 DOI: 10.1513/Annalsats.201408-380Oc  0.389
2015 Lemaitre RN, King IB, Kabagambe EK, Wu JH, McKnight B, Manichaikul A, Guan W, Sun Q, Chasman DI, Foy M, Wang L, Zhu J, Siscovick DS, Tsai MY, Arnett DK, et al. Genetic loci associated with circulating levels of very long-chain saturated fatty acids. Journal of Lipid Research. 56: 176-84. PMID 25378659 DOI: 10.1194/Jlr.M052456  0.368
2015 Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, ... ... Manichaikul A, et al. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry. 20: 647-56. PMID 25288136 DOI: 10.1038/Mp.2014.107  0.429
2015 Dijkstra AE, Boezen HM, van den Berge M, Vonk JM, Hiemstra PS, Barr RG, Burkart KM, Manichaikul A, Pottinger TD, Silverman EK, Cho MH, Crapo JD, Beaty TH, Bakke P, Gulsvik A, et al. Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD. The European Respiratory Journal. 45: 60-75. PMID 25234806 DOI: 10.1183/09031936.00093314  0.403
2014 Qi Q, Kilpeläinen TO, Downer MK, Tanaka T, Smith CE, Sluijs I, Sonestedt E, Chu AY, Renström F, Lin X, Ängquist LH, Huang J, Liu Z, Li Y, Asif Ali M, ... ... Manichaikul A, et al. FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Human Molecular Genetics. 23: 6961-72. PMID 25104851 DOI: 10.1093/Hmg/Ddu411  0.342
2014 Allen EK, Manichaikul A, Chen WM, Rich SS, Daly KA, Sale MM. Evaluation of replication of variants associated with genetic risk of otitis media. Plos One. 9: e104212. PMID 25089819 DOI: 10.1371/Journal.Pone.0104212  0.399
2014 Smolonska J, Koppelman GH, Wijmenga C, Vonk JM, Zanen P, Bruinenberg M, Curjuric I, Imboden M, Thun GA, Franke L, Probst-Hensch NM, Nürnberg P, Riemersma RA, van Schayck CP, Loth DW, ... ... Manichaikul A, et al. Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis. The European Respiratory Journal. 44: 860-72. PMID 24993907 DOI: 10.1183/09031936.00001914  0.393
2014 Street VA, Kujawa SG, Manichaikul A, Broman KW, Kallman JC, Shilling DJ, Iwata AJ, Robinson LC, Robbins CA, Li J, Liberman MC, Tempel BL. Resistance to noise-induced hearing loss in 129S6 and MOLF mice: identification of independent, overlapping, and interacting chromosomal regions. Journal of the Association For Research in Otolaryngology : Jaro. 15: 721-38. PMID 24952082 DOI: 10.1007/S10162-014-0472-X  0.523
2014 Loth DW, Artigas MS, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, ... ... Manichaikul A, et al. Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nature Genetics. 46: 669-77. PMID 24929828 DOI: 10.1038/Ng.3011  0.362
2014 Guan W, Steffen BT, Lemaitre RN, Wu JH, Tanaka T, Manichaikul A, Foy M, Rich SS, Wang L, Nettleton JA, Tang W, Gu X, Bandinelli S, King IB, McKnight B, et al. Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. Circulation. Cardiovascular Genetics. 7: 321-31. PMID 24823311 DOI: 10.1161/Circgenetics.113.000208  0.328
2014 Mesner LD, Ray B, Hsu YH, Manichaikul A, Lum E, Bryda EC, Rich SS, Rosen CJ, Criqui MH, Allison M, Budoff MJ, Clemens TL, Farber CR. Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density. The Journal of Clinical Investigation. 124: 2736-49. PMID 24789909 DOI: 10.1172/Jci73072  0.363
2014 Manichaikul A, Rich SS, Perry H, Yeboah J, Law M, Davis M, Parker M, Ragosta M, Connelly JJ, McNamara CA, Taylor AM. A functionally significant polymorphism in ID3 is associated with human coronary pathology. Plos One. 9: e90222. PMID 24603695 DOI: 10.1371/Journal.Pone.0090222  0.353
2014 Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, Isaacs A, Jakobsdottir J, Feitosa MF, Davies G, Huffman JE, ... Manichaikul A, et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. American Journal of Human Genetics. 94: 223-32. PMID 24507774 DOI: 10.1016/J.Ajhg.2014.01.009  0.328
2014 Manichaikul A, Hoffman EA, Smolonska J, Gao W, Cho MH, Baumhauer H, Budoff M, Austin JH, Washko GR, Carr JJ, Kaufman JD, Pottinger T, Powell CA, Wijmenga C, Zanen P, et al. Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study. American Journal of Respiratory and Critical Care Medicine. 189: 408-18. PMID 24383474 DOI: 10.1164/Rccm.201306-1061Oc  0.395
2014 Burkart KM, Manichaikul A, Wilk JB, Ahmed FS, Burke GL, Enright P, Hansel NN, Haynes D, Heckbert SR, Hoffman EA, Kaufman JD, Kurai J, Loehr L, London SJ, Meng Y, et al. APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema. The European Respiratory Journal. 43: 1003-17. PMID 23900982 DOI: 10.1183/09031936.00147612  0.375
2014 Allen EK, Manichaikul A, Chen W, Rich SS, Daly KA, Sale MM. Power was computed using TDT Power Calculator [15] varying SNP minor allele frequency (MAF) and genetic relative risk (GRR). Plos One. DOI: 10.1371/Journal.Pone.0104212.T004  0.306
2013 Tanaka T, Ngwa JS, van Rooij FJ, Zillikens MC, Wojczynski MK, Frazier-Wood AC, Houston DK, Kanoni S, Lemaitre RN, Luan J, Mikkilä V, Renstrom F, Sonestedt E, Zhao JH, Chu AY, ... ... Manichaikul A, et al. Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. The American Journal of Clinical Nutrition. 97: 1395-402. PMID 23636237 DOI: 10.3945/Ajcn.112.052183  0.418
2013 Wu JH, Lemaitre RN, Manichaikul A, Guan W, Tanaka T, Foy M, Kabagambe EK, Djousse L, Siscovick D, Fretts AM, Johnson C, King IB, Psaty BM, McKnight B, Rich SS, et al. Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Circulation. Cardiovascular Genetics. 6: 171-83. PMID 23362303 DOI: 10.1161/Circgenetics.112.964619  0.369
2013 Hruby A, Ngwa JS, Renström F, Wojczynski MK, Ganna A, Hallmans G, Houston DK, Jacques PF, Kanoni S, Lehtimäki T, Lemaitre RN, Manichaikul A, North KE, Ntalla I, Sonestedt E, et al. Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies. The Journal of Nutrition. 143: 345-53. PMID 23343670 DOI: 10.3945/Jn.112.172049  0.322
2013 Frazier-Wood AC, Manichaikul A, Aslibekyan S, Borecki IB, Goff DC, Hopkins PN, Lai CQ, Ordovas JM, Post WS, Rich SS, Sale MM, Siscovick D, Straka RJ, Tiwari HK, Tsai MY, et al. Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity. Human Genetics. 132: 405-13. PMID 23263444 DOI: 10.1007/S00439-012-1256-1  0.399
2013 Nettleton JA, Hivert MF, Lemaitre RN, McKeown NM, Mozaffarian D, Tanaka T, Wojczynski MK, Hruby A, Djoussé L, Ngwa JS, Follis JL, Dimitriou M, Ganna A, Houston DK, Kanoni S, ... ... Manichaikul A, et al. Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. American Journal of Epidemiology. 177: 103-15. PMID 23255780 DOI: 10.1093/Aje/Kws297  0.37
2013 Richardson K, Nettleton JA, Rotllan N, Tanaka T, Smith CE, Lai CQ, Parnell LD, Lee YC, Lahti J, Lemaitre RN, Manichaikul A, Keller M, Mikkilä V, Ngwa J, van Rooij FJ, et al. Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. American Journal of Human Genetics. 92: 5-14. PMID 23246289 DOI: 10.1016/J.Ajhg.2012.10.020  0.375
2012 Hancock DB, Artigas MS, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, et al. Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. Plos Genetics. 8: e1003098. PMID 23284291 DOI: 10.1371/Journal.Pgen.1003098  0.38
2012 Wilk JB, Shrine NR, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AV, Heckbert SR, Smolonska J, Tang W, Loth DW, Curjuric I, Hui J, Cho MH, Latourelle JC, et al. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. American Journal of Respiratory and Critical Care Medicine. 186: 622-32. PMID 22837378 DOI: 10.1164/Rccm.201202-0366Oc  0.407
2012 Manichaikul A, Naj AC, Herrington D, Post W, Rich SS, Rodriguez A. Association of SCARB1 variants with subclinical atherosclerosis and incident cardiovascular disease: the multi-ethnic study of atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1991-9. PMID 22628436 DOI: 10.1161/Atvbaha.112.249714  0.343
2012 Manichaikul A, Palmas W, Rodriguez CJ, Peralta CA, Divers J, Guo X, Chen WM, Wong Q, Williams K, Kerr KF, Taylor KD, Tsai MY, Goodarzi MO, Sale MM, Diez-Roux AV, et al. Population structure of Hispanics in the United States: the multi-ethnic study of atherosclerosis. Plos Genetics. 8: e1002640. PMID 22511882 DOI: 10.1371/Journal.Pgen.1002640  0.361
2012 Manichaikul A, Chen WM, Williams K, Wong Q, Sale MM, Pankow JS, Tsai MY, Rotter JI, Rich SS, Mychaleckyj JC. Analysis of family- and population-based samples in cohort genome-wide association studies. Human Genetics. 131: 275-87. PMID 21805149 DOI: 10.1007/S00439-011-1071-0  0.307
2011 Chen WM, Manichaikul A, Rich SS. Identifying variants that contribute to linkage for dichotomous and quantitative traits in extended pedigrees. Bmc Proceedings. S68. PMID 22373516 DOI: 10.1186/1753-6561-5-S9-S68  0.344
2011 Soler Artigas M, Loth DW, Wain LV, Gharib SA, Obeidat M, Tang W, Zhai G, Zhao JH, Smith AV, Huffman JE, Albrecht E, Jackson CM, Evans DM, Cadby G, Fornage M, ... Manichaikul A, et al. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nature Genetics. 43: 1082-90. PMID 21946350 DOI: 10.1038/Ng.941  0.331
2011 Lemaitre RN, Tanaka T, Tang W, Manichaikul A, Foy M, Kabagambe EK, Nettleton JA, King IB, Weng LC, Bhattacharya S, Bandinelli S, Bis JC, Rich SS, Jacobs DR, Cherubini A, et al. Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. Plos Genetics. 7: e1002193. PMID 21829377 DOI: 10.1371/Journal.Pgen.1002193  0.39
2011 Chang RL, Ghamsari L, Manichaikul A, Hom EF, Balaji S, Fu W, Shen Y, Hao T, Palsson BØ, Salehi-Ashtiani K, Papin JA. Metabolic network reconstruction of Chlamydomonas offers insight into light-driven algal metabolism. Molecular Systems Biology. 7: 518. PMID 21811229 DOI: 10.1038/Msb.2011.52  0.614
2010 Manichaikul A, Mychaleckyj JC, Rich SS, Daly K, Sale M, Chen WM. Robust relationship inference in genome-wide association studies. Bioinformatics (Oxford, England). 26: 2867-73. PMID 20926424 DOI: 10.1093/Bioinformatics/Btq559  0.373
2010 Manichaikul A, Moon JY, Sen S, Yandell BS, Broman KW. A model selection approach for the identification of quantitative trait loci in experimental crosses, allowing epistasis (Genetics 181 (1077-1086)) Genetics. 184: 607. DOI: 10.1534/Genetics.109.112912  0.573
2009 Shavit JA, Manichaikul A, Lemmerhirt HL, Broman KW, Ginsburg D. Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice. Blood. 114: 5368-74. PMID 19789385 DOI: 10.1182/Blood-2009-07-233213  0.57
2009 Chen WM, Manichaikul A, Rich SS. A generalized family-based association test for dichotomous traits. American Journal of Human Genetics. 85: 364-76. PMID 19732865 DOI: 10.1016/J.Ajhg.2009.08.003  0.365
2009 Manichaikul A, Ghamsari L, Hom EF, Lin C, Murray RR, Chang RL, Balaji S, Hao T, Shen Y, Chavali AK, Thiele I, Yang X, Fan C, Mello E, Hill DE, et al. Metabolic network analysis integrated with transcript verification for sequenced genomes. Nature Methods. 6: 589-92. PMID 19597503 DOI: 10.1038/Nmeth.1348  0.711
2009 Fushan AA, Simons CT, Slack JP, Manichaikul A, Drayna D. Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose. Current Biology : Cb. 19: 1288-93. PMID 19559618 DOI: 10.1016/J.Cub.2009.06.015  0.335
2009 Manichaikul A, Broman KW. Binary trait mapping in experimental crosses with selective genotyping. Genetics. 182: 863-74. PMID 19416941 DOI: 10.1534/Genetics.108.098913  0.595
2009 Manichaikul A, Moon JY, Sen S, Yandell BS, Broman KW. A model selection approach for the identification of quantitative trait loci in experimental crosses, allowing epistasis. Genetics. 181: 1077-86. PMID 19104078 DOI: 10.1534/Genetics.108.094565  0.551
2007 Manichaikul A, Palmer AA, Sen S, Broman KW. Significance thresholds for quantitative trait locus mapping under selective genotyping. Genetics. 177: 1963-6. PMID 17720902 DOI: 10.1534/Genetics.107.080093  0.573
2007 Rajagopal SK, Ma Q, Obler D, Shen J, Manichaikul A, Tomita-Mitchell A, Boardman K, Briggs C, Garg V, Srivastava D, Goldmuntz E, Broman KW, Benson DW, Smoot LB, Pu WT. Spectrum of heart disease associated with murine and human GATA4 mutation. Journal of Molecular and Cellular Cardiology. 43: 677-85. PMID 17643447 DOI: 10.1016/J.Yjmcc.2007.06.004  0.538
2006 Broman KW, Sen S, Owens SE, Manichaikul A, Southard-Smith EM, Churchill GA. The X chromosome in quantitative trait locus mapping. Genetics. 174: 2151-8. PMID 17028340 DOI: 10.1534/Genetics.106.061176  0.533
2006 Manichaikul A, Dupuis J, Sen S, Broman KW. Poor performance of bootstrap confidence intervals for the location of a quantitative trait locus. Genetics. 174: 481-9. PMID 16783000 DOI: 10.1534/Genetics.106.061549  0.593
2001 Drayna D, Manichaikul A, Lange Md, Snieder H, Spector T. Genetic Correlates of Musical Pitch Recognition in Humans Science. 291: 1969-1972. PMID 11239158 DOI: 10.1126/Science.291.5510.1969  0.309
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