| Year |
Citation |
Score |
| 2023 |
Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, ... ... Thorne CA, et al. USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling. Science Signaling. 16: eabn8372. PMID 36749823 DOI: 10.1126/scisignal.abn8372 |
0.581 |
|
| 2023 |
Cantoria MJ, Alizadeh E, Ravi J, Varghese RP, Bunnag N, Pond KW, Kettenbach AN, Ahmed Y, Paek AL, Tyson JJ, Doubrovinski K, Lee E, Thorne CA. Feedback in the β-catenin destruction complex imparts bistability and cellular memory. Proceedings of the National Academy of Sciences of the United States of America. 120: e2208787120. PMID 36598937 DOI: 10.1073/pnas.2208787120 |
0.304 |
|
| 2022 |
Pond KW, Morris JM, Alkhimenok O, Varghese RP, Cabel CC, Ellis NA, Chakrabarti J, Zavros Y, Merchant JL, Thorne CA, Paek AL. Live-cell imaging in human colonic monolayers reveals ERK waves limit the stem cell compartment to maintain epithelial homeostasis. Elife. 11. PMID 36094159 DOI: 10.7554/eLife.78837 |
0.335 |
|
| 2021 |
Wu MH, Padilla-Rodriguez M, Blum I, Camenisch A, Figliuolo da Paz V, Ollerton M, Muller J, Momtaz S, Mitchell SAT, Kiela P, Thorne C, Wilson JM, Cox CM. Proliferation in the developing intestine is regulated by the endosomal protein Endotubin. Developmental Biology. PMID 34411593 DOI: 10.1016/j.ydbio.2021.08.009 |
0.362 |
|
| 2020 |
Perez-Miller S, Patek M, Moutal A, Cabel CR, Thorne CA, Campos SK, Khanna R. In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike protein. Biorxiv : the Preprint Server For Biology. PMID 32995772 DOI: 10.1101/2020.09.22.308783 |
0.305 |
|
| 2020 |
Pond KW, Doubrovinski K, Thorne CA. Wnt/β-catenin Signaling in Tissue Self-Organization. Genes. 11. PMID 32823838 DOI: 10.3390/Genes11080939 |
0.375 |
|
| 2020 |
Sanman LE, Chen IW, Bieber JM, Thorne CA, Wu LF, Altschuler SJ. Generation and Quantitative Imaging of Enteroid Monolayers. Methods in Molecular Biology (Clifton, N.J.). 2171: 99-113. PMID 32705637 DOI: 10.1007/978-1-0716-0747-3_6 |
0.302 |
|
| 2019 |
Cabel CR, Alizadeh E, Robbins DJ, Ahmed Y, Lee E, Thorne CA. Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells. Developmental Cell. 49: 827-828. PMID 31211991 DOI: 10.1016/J.Devcel.2019.05.039 |
0.57 |
|
| 2018 |
Miyata N, Morris LL, Chen Q, Thorne C, Singla A, Zhu W, Winter M, Melton SD, Li H, Sifuentes-Dominguez L, Llano E, Huff-Hardy K, Starokadomskyy P, Lopez A, Reese TA, et al. Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation. Cell Reports. 24: 2342-2355. PMID 30157428 DOI: 10.1016/J.Celrep.2018.07.066 |
0.314 |
|
| 2018 |
Thorne CA, Chen IW, Sanman LE, Cobb MH, Wu LF, Altschuler SJ. Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization. Developmental Cell. PMID 29503158 DOI: 10.1016/J.Devcel.2018.01.024 |
0.562 |
|
| 2017 |
Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, et al. Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors. Science Signaling. 10. PMID 28655862 DOI: 10.1126/Scisignal.Aak9916 |
0.685 |
|
| 2016 |
Coate KC, Hernandez G, Thorne CA, Sun S, Le TD, Vale K, Kliewer SA, Mangelsdorf DJ. FGF21 Is an Exocrine Pancreas Secretagogue. Cell Metabolism. PMID 28089565 DOI: 10.1016/J.Cmet.2016.12.004 |
0.348 |
|
| 2016 |
Coster AD, Thorne CA, Wu LF, Altschuler SJ. Examining crosstalk among Transforming Growth Factor β, Bone Morphogen Protein, and Wnt pathways. The Journal of Biological Chemistry. PMID 27895117 DOI: 10.1074/Jbc.M116.759654 |
0.496 |
|
| 2016 |
Wang Z, Tacchelly-Benites O, Yang E, Thorne CA, Nojima H, Lee E, Ahmed Y. Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase. Genetics. PMID 26975665 DOI: 10.1534/Genetics.115.183244 |
0.522 |
|
| 2015 |
Karra AS, Taylor CA, Thorne CA, Cobb MH. A Kinase Divided. Cancer Cell. 28: 145-7. PMID 26267529 DOI: 10.1016/J.Ccell.2015.07.008 |
0.557 |
|
| 2015 |
Thorne CA, Wichaidit C, Coster AD, Posner BA, Wu LF, Altschuler SJ. GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors. Nature Chemical Biology. 11: 58-63. PMID 25402767 DOI: 10.1038/Nchembio.1690 |
0.53 |
|
| 2013 |
Hao J, Ao A, Zhou L, Murphy CK, Frist AY, Keel JJ, Thorne CA, Kim K, Lee E, Hong CC. Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen. Cell Reports. 4: 898-904. PMID 24012757 DOI: 10.1016/J.Celrep.2013.07.047 |
0.505 |
|
| 2013 |
Saito-Diaz K, Chen TW, Wang X, Thorne CA, Wallace HA, Page-McCaw A, Lee E. The way Wnt works: components and mechanism. Growth Factors (Chur, Switzerland). 31: 1-31. PMID 23256519 DOI: 10.3109/08977194.2012.752737 |
0.516 |
|
| 2012 |
Hang BI, Thorne CA, Robbins DJ, Huppert SS, Lee LA, Lee E. Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs. Bioorganic & Medicinal Chemistry. 20: 1869-77. PMID 22261025 DOI: 10.1016/J.Bmc.2011.12.044 |
0.58 |
|
| 2011 |
Ni TT, Rellinger EJ, Mukherjee A, Xie S, Stephens L, Thorne CA, Kim K, Hu J, Lee E, Marnett L, Hatzopoulos AK, Zhong TP. Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling. Chemistry & Biology. 18: 1658-68. PMID 22195568 DOI: 10.1016/J.Chembiol.2011.09.015 |
0.46 |
|
| 2011 |
Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, et al. A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts. Journal of Biomolecular Screening. 16: 995-1006. PMID 21859680 DOI: 10.1177/1087057111416657 |
0.622 |
|
| 2010 |
Saraswati S, Alfaro MP, Thorne CA, Atkinson J, Lee E, Young PP. Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling. Plos One. 5: e15521. PMID 21170416 DOI: 10.1371/Journal.Pone.0015521 |
0.468 |
|
| 2010 |
Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, et al. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α. Nature Chemical Biology. 6: 829-36. PMID 20890287 DOI: 10.1038/Nchembio.453 |
0.645 |
|
| 2010 |
Alfaro MP, Vincent A, Saraswati S, Thorne CA, Hong CC, Lee E, Young PP. sFRP2 suppression of bone morphogenic protein (BMP) and Wnt signaling mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair. The Journal of Biological Chemistry. 285: 35645-53. PMID 20826809 DOI: 10.1074/Jbc.M110.135335 |
0.412 |
|
| 2010 |
Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E. Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity. Science Signaling. 3: ra37. PMID 20460648 DOI: 10.1126/Scisignal.2000647 |
0.415 |
|
| 2008 |
Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E. LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin. Proceedings of the National Academy of Sciences of the United States of America. 105: 8032-7. PMID 18509060 DOI: 10.1073/Pnas.0803025105 |
0.416 |
|
| 2007 |
Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E. Lrp6 is required for convergent extension during Xenopus gastrulation. Development (Cambridge, England). 134: 4095-106. PMID 17965054 DOI: 10.1242/Dev.010272 |
0.465 |
|
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