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Jeffrey Holmes, M.D. Ph.D - Publications

Affiliations: 
Biomedical Engineering University of Virginia, Charlottesville, VA 
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yoshida K, Saucerman JJ, Holmes JW. Multiscale model of heart growth during pregnancy: integrating mechanical and hormonal signaling. Biomechanics and Modeling in Mechanobiology. PMID 35668305 DOI: 10.1007/s10237-022-01589-y  0.709
2021 Oomen PJA, Phung TN, Weinberg SH, Bilchick KC, Holmes JW. A rapid electromechanical model to predict reverse remodeling following cardiac resynchronization therapy. Biomechanics and Modeling in Mechanobiology. PMID 34816336 DOI: 10.1007/s10237-021-01532-7  0.32
2021 Rogers JD, Holmes JW, Saucerman JJ, Richardson WJ. Mechano-chemo signaling interactions modulate matrix production by cardiac fibroblasts. Matrix Biology Plus. 10: 100055. PMID 34195592 DOI: 10.1016/j.mbplus.2020.100055  0.745
2021 Rogers JD, Holmes JW, Saucerman JJ, Richardson WJ. Mechano-chemo signaling interactions modulate matrix production by cardiac fibroblasts. Matrix Biology Plus. 10: 100055. PMID 34195592 DOI: 10.1016/j.mbplus.2020.100055  0.745
2021 Zeigler AC, Chandrabhatla AS, Christiansen SL, Nelson AR, Holmes JW, Saucerman JJ. Network model-based screen for FDA-approved drugs affecting cardiac fibrosis. Cpt: Pharmacometrics & Systems Pharmacology. PMID 33571402 DOI: 10.1002/psp4.12599  0.722
2020 Estrada AC, Yoshida K, Saucerman JJ, Holmes JW. A multiscale model of cardiac concentric hypertrophy incorporating both mechanical and hormonal drivers of growth. Biomechanics and Modeling in Mechanobiology. PMID 32970240 DOI: 10.1007/s10237-020-01385-6  0.735
2020 Yoshida K, Holmes JW. Computational models of cardiac hypertrophy. Progress in Biophysics and Molecular Biology. PMID 32702352 DOI: 10.1016/j.pbiomolbio.2020.07.001  0.362
2020 Zeigler AC, Nelson AR, Chandrabhatla AS, Brazhkina O, Holmes JW, Saucerman JJ. Computational Model Predicts Paracrine and Intracellular Drivers of Fibroblast Phenotype After Myocardial Infarction. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 32209358 DOI: 10.1016/J.Matbio.2020.03.007  0.737
2019 Rikard SM, Athey TL, Nelson AR, Christiansen SLM, Lee JJ, Holmes JW, Peirce SM, Saucerman JJ. Multiscale Coupling of an Agent-Based Model of Tissue Fibrosis and a Logic-Based Model of Intracellular Signaling. Frontiers in Physiology. 10: 1481. PMID 31920691 DOI: 10.3389/Fphys.2019.01481  0.745
2019 Yoshida K, McCulloch AD, Omens JH, Holmes JW. Predictions of hypertrophy and its regression in response to pressure overload. Biomechanics and Modeling in Mechanobiology. PMID 31813071 DOI: 10.1007/S10237-019-01271-W  0.509
2016 Zeigler AC, Richardson WJ, Holmes JW, Saucerman JJ. A computational model of cardiac fibroblast signaling predicts context-dependent drivers of myofibroblast differentiation. Journal of Molecular and Cellular Cardiology. PMID 27017945 DOI: 10.1016/J.Yjmcc.2016.03.008  0.742
2015 Zeigler AC, Richardson WJ, Holmes JW, Saucerman JJ. Computational modeling of cardiac fibroblasts and fibrosis. Journal of Molecular and Cellular Cardiology. PMID 26608708 DOI: 10.1016/J.Yjmcc.2015.11.020  0.756
2015 Lin D, French BA, Xu Y, Hossack JA, Holmes JW. An ultrasound-driven kinematic model for deformation of the infarcted mouse left ventricle incorporating a near-incompressibility constraint. Ultrasound in Medicine & Biology. 41: 532-41. PMID 25542490 DOI: 10.1016/J.Ultrasmedbio.2014.09.002  0.315
2014 Rouillard AD, Holmes JW. Coupled agent-based and finite-element models for predicting scar structure following myocardial infarction. Progress in Biophysics and Molecular Biology. 115: 235-43. PMID 25009995 DOI: 10.1016/j.pbiomolbio.2014.06.010  0.32
2014 Kenwood BM, Weaver JL, Bajwa A, Poon IK, Byrne FL, Murrow BA, Calderone JA, Huang L, Divakaruni AS, Tomsig JL, Okabe K, Lo RH, Cameron Coleman G, Columbus L, Yan Z, ... ... Holmes JW, et al. Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane. Molecular Metabolism. 3: 114-23. PMID 24634817 DOI: 10.1016/J.Molmet.2013.11.005  0.654
2014 Bilchick KC, Kuruvilla S, Hamirani YS, Ramachandran R, Clarke S, Cui S, Salerno M, Holmes J, Kramer CM, Epstein FH. Electromechanical and scar characteristics at left ventricular lead implant site in the context of overall dyssynchrony with cine DENSE predict cardiac resynchronization therapy outcomes Journal of Cardiovascular Magnetic Resonance. 16. DOI: 10.1186/1532-429X-16-S1-O53  0.382
2012 Rouillard AD, Holmes JW. Mechanical regulation of fibroblast migration and collagen remodelling in healing myocardial infarcts. The Journal of Physiology. 590: 4585-602. PMID 22495588 DOI: 10.1113/jphysiol.2012.229484  0.312
2010 Fomovsky GM, Thomopoulos S, Holmes JW. Contribution of extracellular matrix to the mechanical properties of the heart. Journal of Molecular and Cellular Cardiology. 48: 490-6. PMID 19686759 DOI: 10.1016/J.Yjmcc.2009.08.003  0.311
2009 Duan Q, Angelini ED, Herz SL, Ingrassia CM, Costa KD, Holmes JW, Homma S, Laine AF. Region-based endocardium tracking on real-time three-dimensional ultrasound. Ultrasound in Medicine & Biology. 35: 256-65. PMID 18963396 DOI: 10.1016/J.Ultrasmedbio.2008.08.012  0.554
2008 Lee EJ, Holmes JW, Costa KD. Remodeling of engineered tissue anisotropy in response to altered loading conditions. Annals of Biomedical Engineering. 36: 1322-34. PMID 18470621 DOI: 10.1007/S10439-008-9509-9  0.525
2007 Lee WN, Ingrassia CM, Fung-Kee-Fung SD, Costa KD, Holmes JW, Konofagou EE. Theoretical quality assessment of myocardial elastography with in vivo validation. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 54: 2233-45. PMID 18051158 DOI: 10.1109/Tuffc.2007.528  0.545
2007 Cheng Y, George I, Yi GH, Reiken S, Gu A, Tao YK, Muraskin J, Qin S, He KL, Hay I, Yu K, Oz MC, Burkhoff D, Holmes J, Wang J. Bradycardic therapy improves left ventricular function and remodeling in dogs with coronary embolization-induced chronic heart failure. The Journal of Pharmacology and Experimental Therapeutics. 321: 469-76. PMID 17277196 DOI: 10.1124/Jpet.106.118109  0.329
2007 George I, Cheng Y, Yi GH, He KL, Li X, Oz MC, Holmes J, Wang J. Effect of passive cardiac containment on ventricular synchrony and cardiac function in awake dogs. European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 31: 55-64. PMID 17081764 DOI: 10.1016/J.Ejcts.2006.09.024  0.409
2007 Ingrassia CM, Usyk TP, Kerckhoffs RCP, McCulloch AD, Costa KD, Holmes JW. Model-based development of four-dimensional wall motion measures Computer Methods in Applied Mechanics and Engineering. 196: 3061-3069. DOI: 10.1016/J.Cma.2006.06.016  0.634
2006 Herz SL, Ingrassia CM, Costa KD, Holmes JW. Model-based screening of wall motion measures for detection of ischemia in three-dimensional cardiac images. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 628-31. PMID 17946412 DOI: 10.1109/IEMBS.2006.260387  0.558
2005 Duan Q, Herz S, Ingrassia C, Costa K, Holmes J, Laine A, Angelini E, Gerard O, Homma S. Dynamic cardiac information from optical flow using four dimensional ultrasound. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 4: 4465-8. PMID 17281228 DOI: 10.1109/IEMBS.2005.1615458  0.592
2005 Herz SL, Ingrassia CM, Homma S, Costa KD, Holmes JW. Parameterization of left ventricular wall motion for detection of regional ischemia. Annals of Biomedical Engineering. 33: 912-9. PMID 16060531 DOI: 10.1007/S10439-005-3312-7  0.545
2005 Duan Q, Angelini ED, Herz SL, Gerard O, Allain P, Ingrassia CM, Costa KD, Holmes JW, Homma S, Laine AF. Tracking of LV endocardial surface on real-time three-dimensional ultrasound with optical flow Lecture Notes in Computer Science. 3504: 434-445.  0.491
2003 Costa KD, Lee EJ, Holmes JW. Creating alignment and anisotropy in engineered heart tissue: role of boundary conditions in a model three-dimensional culture system. Tissue Engineering. 9: 567-77. PMID 13678436 DOI: 10.1089/107632703768247278  0.573
2002 Thomopoulos S, Knezevic V, Costa KD, Holmes JW. Development of anisotropy in fibroblast populated collagen gels Asme International Mechanical Engineering Congress and Exposition, Proceedings. 253-254. DOI: 10.1115/IMECE2002-32781  0.488
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