Ana Belen Elgoyhen, Ph.D. - Publications

Affiliations: 
INGEBI, University of Buenos Aires 
Area:
molecular neuropharmacology

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhang Y, Hiel H, Vincent PFY, Wood MB, Elgoyhen AB, Chien W, Lauer A, Fuchs PA. Engineering olivocochlear inhibition to reduce acoustic trauma. Molecular Therapy. Methods & Clinical Development. 29: 17-31. PMID 36941920 DOI: 10.1016/j.omtm.2023.02.011  0.626
2023 Elgoyhen AB. The α9α10 acetylcholine receptor: A non-neuronal nicotinic receptor. Pharmacological Research. 190: 106735. PMID 36931539 DOI: 10.1016/j.phrs.2023.106735  0.401
2022 Elgoyhen AB. The α9α10 nicotinic acetylcholine receptor: a compelling drug target for hearing loss? Expert Opinion On Therapeutic Targets. 26: 291-302. PMID 35225139 DOI: 10.1080/14728222.2022.2047931  0.336
2021 Lipovsek M, Marcovich I, Elgoyhen AB. The Hair Cell α9α10 Nicotinic Acetylcholine Receptor: Odd Cousin in an Old Family. Frontiers in Cellular Neuroscience. 15: 785265. PMID 34867208 DOI: 10.3389/fncel.2021.785265  0.448
2021 Plazas PV, Elgoyhen AB. The Cholinergic Lateral Line Efferent Synapse: Structural, Functional and Molecular Similarities With Those of the Cochlea. Frontiers in Cellular Neuroscience. 15: 765083. PMID 34712122 DOI: 10.3389/fncel.2021.765083  0.399
2021 Moglie MJ, Marcovich I, Corradi J, Carpaneto Freixas AE, Gallino S, Plazas PV, Bouzat C, Lipovsek M, Elgoyhen AB. Loss of Choline Agonism in the Inner Ear Hair Cell Nicotinic Acetylcholine Receptor Linked to the α10 Subunit. Frontiers in Molecular Neuroscience. 14: 639720. PMID 33613194 DOI: 10.3389/fnmol.2021.639720  0.489
2020 Carpaneto Freixas AE, Moglie MJ, Castagnola T, Salatino L, Domene S, Marcovich I, Gallino S, Wedemeyer C, Goutman JD, Plazas PV, Elgoyhen AB. Unravelling the molecular players at the cholinergic efferent synapse of the zebrafish lateral line. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33203744 DOI: 10.1523/JNEUROSCI.1772-20.2020  0.407
2020 Vattino LG, Wedemeyer C, Elgoyhen AB, Katz E. Functional postnatal maturation of the medial olivocochlear efferent-outer hair cell synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32430293 DOI: 10.1523/JNEUROSCI.2409-19.2020  0.341
2020 Boero LE, Castagna VC, Terreros G, Moglie MJ, Silva S, Maass JC, Fuchs PA, Delano PH, Elgoyhen AB, Gómez-Casati ME. Preventing presbycusis in mice with enhanced medial olivocochlear feedback. Proceedings of the National Academy of Sciences of the United States of America. PMID 32393641 DOI: 10.1073/Pnas.2000760117  0.641
2020 Marcovich I, Moglie MJ, Carpaneto Freixas AE, Trigila AP, Franchini LF, Plazas PV, Lipovsek M, Elgoyhen AB. Distinct Evolutionary Trajectories of Neuronal and Hair Cell Nicotinic Acetylcholine Receptors. Molecular Biology and Evolution. 37: 1070-1089. PMID 31821508 DOI: 10.1093/Molbev/Msz290  0.434
2019 Di Guilmi MN, Boero LE, Castagna VC, Rodríguez-Contreras A, Wedemeyer C, Gómez-Casati ME, Elgoyhen AB. Strengthening of the efferent olivocochlear system leads to synaptic dysfunction and tonotopy disruption of a central auditory nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31217330 DOI: 10.1523/Jneurosci.2536-18.2019  0.493
2019 Pisciottano F, Cinalli AR, Stopiello M, Castagna VC, Elgoyhen AB, Rubinstein M, Gómez-Casati ME, Franchini LF. Inner Ear Genes Underwent Positive Selection and Adaptation in the Mammalian Lineage. Molecular Biology and Evolution. PMID 31137036 DOI: 10.1093/Molbev/Msz077  0.351
2018 Boero LE, Castagna VC, Di Guilmi MN, Goutman JD, Elgoyhen AB, Gómez-Casati ME. Enhancement of the Medial Olivocochlear System Prevents Hidden Hearing Loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 38: 7440-7451. PMID 30030403 DOI: 10.1523/Jneurosci.0363-18.2018  0.384
2018 Morley BJ, Whiteaker P, Elgoyhen AB. Commentary: Nicotinic Acetylcholine Receptor α9 and α10 Subunits Are Expressed in the Brain of Mice. Frontiers in Cellular Neuroscience. 12: 104. PMID 29765305 DOI: 10.3389/Fncel.2018.00104  0.302
2018 Wedemeyer C, Vattino LG, Moglie MJ, Ballestero J, Maison SF, Di Guilmi MN, Taranda J, Liberman MC, Fuchs PA, Katz E, Elgoyhen AB. A Gain-of-Function Mutation in the α9 Nicotinic Acetylcholine Receptor Alters Medial Olivocochlear Efferent Short Term Synaptic Plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29572431 DOI: 10.1523/Jneurosci.2528-17.2018  0.682
2018 Moglie MJ, Fuchs PA, Elgoyhen AB, Goutman JD. Compartmentalization of antagonistic Casignals in developing cochlear hair cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29439202 DOI: 10.1073/Pnas.1719077115  0.658
2017 Lotfipour S, Mojica C, Nakauchi S, Lipovsek M, Silverstein S, Cushman J, Tirtorahardjo J, Poulos A, Elgoyhen AB, Sumikawa K, Fanselow MS, Boulter J. α2* Nicotinic acetylcholine receptors influence hippocampus-dependent learning and memory in adolescent mice. Learning & Memory (Cold Spring Harbor, N.Y.). 24: 231-244. PMID 28507032 DOI: 10.1101/Lm.045369.117  0.407
2017 Boffi JC, Marcovich I, Gill-Thind JK, Corradi J, Collins T, Lipovsek MM, Moglie M, Plazas PV, Craig PO, Millar NS, Bouzat C, Elgoyhen AB. Differential contribution of subunit interfaces to α9α10 nicotinic acetylcholine receptor function. Molecular Pharmacology. PMID 28069778 DOI: 10.1124/Mol.116.107482  0.427
2017 Terreros G, Jorratt P, Aedo C, Elgoyhen AB, Delano PH. Selective Attention to Visual Stimuli Using Auditory Distractors Is Altered in Alpha-9 Nicotinic Receptor Subunit Knock-Out Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7198-209. PMID 27383594 DOI: 10.1523/JNEUROSCI.4031-15.2016  0.322
2016 Arias HR, Ravazzini F, Targowska-Duda KM, Kaczor AA, Feuerbach D, Boffi JC, Draczkowski P, Montag D, Brown BM, Elgoyhen AB, Jozwiak K, Puia G. Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content. The International Journal of Biochemistry & Cell Biology. 76: 19-30. PMID 27129924 DOI: 10.1016/J.Biocel.2016.04.015  0.414
2015 Goutman JD, Elgoyhen AB, Gómez-Casati ME. Cochlear hair cells: The sound-sensing machines. Febs Letters. 589: 3354-61. PMID 26335749 DOI: 10.1016/j.febslet.2015.08.030  0.398
2014 Katz E, Elgoyhen AB. Short-term plasticity and modulation of synaptic transmission at mammalian inhibitory cholinergic olivocochlear synapses. Frontiers in Systems Neuroscience. 8: 224. PMID 25520631 DOI: 10.3389/fnsys.2014.00224  0.425
2014 Lipovsek M, Fierro A, Pérez EG, Boffi JC, Millar NS, Fuchs PA, Katz E, Elgoyhen AB. Tracking the molecular evolution of calcium permeability in a nicotinic acetylcholine receptor. Molecular Biology and Evolution. 31: 3250-65. PMID 25193338 DOI: 10.1093/molbev/msu258  0.603
2013 Johnson SL, Wedemeyer C, Vetter DE, Adachi R, Holley MC, Elgoyhen AB, Marcotti W. Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses. Open Biology. 3: 130163. PMID 24350389 DOI: 10.1098/Rsob.130163  0.523
2013 Wedemeyer C, Zorrilla de San Martín J, Ballestero J, Gómez-Casati ME, Torbidoni AV, Fuchs PA, Bettler B, Elgoyhen AB, Katz E. Activation of presynaptic GABA(B(1a,2)) receptors inhibits synaptic transmission at mammalian inhibitory cholinergic olivocochlear-hair cell synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15477-87. PMID 24068816 DOI: 10.1523/Jneurosci.2554-13.2013  0.638
2013 Boffi JC, Wedemeyer C, Lipovsek M, Katz E, Calvo DJ, Elgoyhen AB. Positive modulation of the α9α10 nicotinic cholinergic receptor by ascorbic acid. British Journal of Pharmacology. 168: 954-65. PMID 22994414 DOI: 10.1111/j.1476-5381.2012.02221.x  0.39
2012 Lipovsek M, Im GJ, Franchini LF, Pisciottano F, Katz E, Fuchs PA, Elgoyhen AB. Phylogenetic differences in calcium permeability of the auditory hair cell cholinergic nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 109: 4308-13. PMID 22371598 DOI: 10.1073/pnas.1115488109  0.674
2012 Liu Y, Han N, Franchini LF, Xu H, Pisciottano F, Elgoyhen AB, Rajan KE, Zhang S. The voltage-gated potassium channel subfamily KQT member 4 (KCNQ4) displays parallel evolution in echolocating bats. Molecular Biology and Evolution. 29: 1441-50. PMID 22319145 DOI: 10.1093/Molbev/Msr310  0.393
2012 Elgoyhen AB, Katz E. The efferent medial olivocochlear-hair cell synapse. Journal of Physiology, Paris. 106: 47-56. PMID 21762779 DOI: 10.1016/J.Jphysparis.2011.06.001  0.509
2012 Elgoyhen AB, Fuchs PA. Efferent innervation and function Oxford Handbook of Auditory Science the Ear. DOI: 10.1093/oxfordhb/9780199233397.013.0010  0.503
2011 Ballestero J, Zorrilla de San Martín J, Goutman J, Elgoyhen AB, Fuchs PA, Katz E. Short-term synaptic plasticity regulates the level of olivocochlear inhibition to auditory hair cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14763-74. PMID 21994392 DOI: 10.1523/Jneurosci.6788-10.2011  0.639
2011 Elgoyhen AB, Franchini LF. Prestin and the cholinergic receptor of hair cells: positively-selected proteins in mammals. Hearing Research. 273: 100-8. PMID 20056140 DOI: 10.1016/J.Heares.2009.12.028  0.459
2011 Boffi JC, Wedemeyer C, Katz E, Calvo DJ, Elgoyhen AB. Ascorbic acid is a positive modulator of α9α10 nicotinic cholinergic receptors Biochemical Pharmacology. 82: 1032. DOI: 10.1016/J.Bcp.2011.07.026  0.438
2009 Murthy V, Taranda J, Elgoyhen AB, Vetter DE. Activity of nAChRs containing alpha9 subunits modulates synapse stabilization via bidirectional signaling programs. Developmental Neurobiology. 69: 931-49. PMID 19790106 DOI: 10.1002/Dneu.20753  0.404
2009 Elgoyhen AB, Katz E, Fuchs PA. The nicotinic receptor of cochlear hair cells: a possible pharmacotherapeutic target? Biochemical Pharmacology. 78: 712-9. PMID 19481062 DOI: 10.1016/J.Bcp.2009.05.023  0.691
2009 McIntosh JM, Absalom N, Chebib M, Elgoyhen AB, Vincler M. Alpha9 nicotinic acetylcholine receptors and the treatment of pain. Biochemical Pharmacology. 78: 693-702. PMID 19477168 DOI: 10.1016/j.bcp.2009.05.020  0.321
2009 Taranda J, Ballestero JA, Hiel H, de Souza FS, Wedemeyer C, Gómez-Casati ME, Lipovsek M, Vetter DE, Fuchs PA, Katz E, Elgoyhen AB. Constitutive expression of the alpha10 nicotinic acetylcholine receptor subunit fails to maintain cholinergic responses in inner hair cells after the onset of hearing. Journal of the Association For Research in Otolaryngology : Jaro. 10: 397-406. PMID 19452222 DOI: 10.1007/S10162-009-0173-Z  0.654
2009 Gómez-Casati ME, Wedemeyer C, Taranda J, Lipovsek M, Dalamon V, Elgoyhen AB, Katz E. Electrical properties and functional expression of ionic channels in cochlear inner hair cells of mice lacking the alpha10 nicotinic cholinergic receptor subunit. Journal of the Association For Research in Otolaryngology : Jaro. 10: 221-32. PMID 19252947 DOI: 10.1007/S10162-009-0164-0  0.485
2009 Taranda J, Maison SF, Ballestero JA, Katz E, Savino J, Vetter DE, Boulter J, Liberman MC, Fuchs PA, Elgoyhen AB. A point mutation in the hair cell nicotinic cholinergic receptor prolongs cochlear inhibition and enhances noise protection. Plos Biology. 7: e18. PMID 19166271 DOI: 10.1371/Journal.Pbio.1000018  0.658
2009 Murthy V, Maison SF, Taranda J, Haque N, Bond CT, Elgoyhen AB, Adelman JP, Liberman MC, Vetter DE. SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells. Molecular and Cellular Neurosciences. 40: 39-49. PMID 18848895 DOI: 10.1016/J.Mcn.2008.08.011  0.4
2009 Lipovsek M, Franchini L, Katz E, Millar N, Fuchs P, Elgoyhen A. Functional consequences of adaptive evolution of the mammalian α9α10 nicotinic receptor Biochemical Pharmacology. 78: 899. DOI: 10.1016/J.Bcp.2009.06.030  0.645
2007 Vetter DE, Katz E, Maison SF, Taranda J, Turcan S, Ballestero J, Liberman MC, Elgoyhen AB, Boulter J. The alpha10 nicotinic acetylcholine receptor subunit is required for normal synaptic function and integrity of the olivocochlear system. Proceedings of the National Academy of Sciences of the United States of America. 104: 20594-9. PMID 18077337 DOI: 10.1073/Pnas.0708545105  0.316
2007 Scheffer D, Sage C, Plazas PV, Huang M, Wedemeyer C, Zhang DS, Chen ZY, Elgoyhen AB, Corey DP, Pingault V. The α1 subunit of nicotinic acetylcholine receptors in the inner ear: transcriptional regulation by ATOH1 and co-expression with the γ subunit in hair cells. Journal of Neurochemistry. 103: 2651-64. PMID 17961150 DOI: 10.1111/j.1471-4159.2007.04980.x  0.37
2007 Zorrilla de San Martín J, Ballestero J, Katz E, Elgoyhen AB, Fuchs PA. Ryanodine is a positive modulator of acetylcholine receptor gating in cochlear hair cells. Journal of the Association For Research in Otolaryngology : Jaro. 8: 474-83. PMID 17647061 DOI: 10.1007/s10162-007-0090-y  0.671
2007 Plazas PV, Savino J, Kracun S, Gomez-Casati ME, Katz E, Parsons CG, Millar NS, Elgoyhen AB. Inhibition of the alpha9alpha10 nicotinic cholinergic receptor by neramexane, an open channel blocker of N-methyl-D-aspartate receptors. European Journal of Pharmacology. 566: 11-9. PMID 17466293 DOI: 10.1016/j.ejphar.2007.03.026  0.371
2006 Franchini LF, Elgoyhen AB. Adaptive evolution in mammalian proteins involved in cochlear outer hair cell electromotility. Molecular Phylogenetics and Evolution. 41: 622-35. PMID 16854604 DOI: 10.1016/j.ympev.2006.05.042  0.377
2005 Plazas PV, Katz E, Gomez-Casati ME, Bouzat C, Elgoyhen AB. Stoichiometry of the alpha9alpha10 nicotinic cholinergic receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10905-12. PMID 16306403 DOI: 10.1523/JNEUROSCI.3805-05.2005  0.359
2005 Ballestero JA, Plazas PV, Kracun S, Gómez-Casati ME, Taranda J, Rothlin CV, Katz E, Millar NS, Elgoyhen AB. Effects of quinine, quinidine, and chloroquine on alpha9alpha10 nicotinic cholinergic receptors. Molecular Pharmacology. 68: 822-9. PMID 15955868 DOI: 10.1124/Mol.105.014431  0.359
2005 Plazas PV, De Rosa MJ, Gomez-Casati ME, Verbitsky M, Weisstaub N, Katz E, Bouzat C, Elgoyhen AB. Key roles of hydrophobic rings of TM2 in gating of the alpha9alpha10 nicotinic cholinergic receptor. British Journal of Pharmacology. 145: 963-74. PMID 15895110 DOI: 10.1038/Sj.Bjp.0706224  0.463
2005 Gómez-Casati ME, Fuchs PA, Elgoyhen AB, Katz E. Biophysical and pharmacological characterization of nicotinic cholinergic receptors in rat cochlear inner hair cells. The Journal of Physiology. 566: 103-18. PMID 15860528 DOI: 10.1113/jphysiol.2005.087155  0.642
2004 Gomez-Casati ME, Katz E, Glowatzki E, Lioudyno MI, Fuchs P, Elgoyhen AB. Linopirdine blocks alpha9alpha10-containing nicotinic cholinergic receptors of cochlear hair cells. Journal of the Association For Research in Otolaryngology : Jaro. 5: 261-9. PMID 15492885 DOI: 10.1007/S10162-004-4025-6  0.663
2004 Katz E, Elgoyhen AB, Gómez-Casati ME, Knipper M, Vetter DE, Fuchs PA, Glowatzki E. Developmental regulation of nicotinic synapses on cochlear inner hair cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7814-20. PMID 15356192 DOI: 10.1523/Jneurosci.2102-04.2004  0.649
2003 Verbitsky M, Plazas PV, Elgoyhen AB. Functional expression and properties of a nicotinic alpha9/5-HT3A chimeric receptor. Neuroreport. 14: 1931-4. PMID 14561923 DOI: 10.1097/00001756-200310270-00010  0.368
2003 Rothlin CV, Lioudyno MI, Silbering AF, Plazas PV, Casati ME, Katz E, Guth PS, Elgoyhen AB. Direct interaction of serotonin type 3 receptor ligands with recombinant and native alpha 9 alpha 10-containing nicotinic cholinergic receptors. Molecular Pharmacology. 63: 1067-74. PMID 12695535 DOI: 10.1124/mol.63.5.1067  0.313
2002 Weisstaub N, Vetter DE, Elgoyhen AB, Katz E. The alpha9alpha10 nicotinic acetylcholine receptor is permeable to and is modulated by divalent cations. Hearing Research. 167: 122-35. PMID 12117536 DOI: 10.1016/S0378-5955(02)00380-5  0.436
2000 Rothlin CV, Katz E, Verbitsky M, Vetter DE, Heinemann SF, Elgoyhen AB. Block of the alpha9 nicotinic receptor by ototoxic aminoglycosides. Neuropharmacology. 39: 2525-32. PMID 11044724 DOI: 10.1016/S0028-3908(00)00056-3  0.39
2000 Verbitsky M, Rothlin CV, Katz E, Elgoyhen AB. Mixed nicotinic-muscarinic properties of the alpha9 nicotinic cholinergic receptor. Neuropharmacology. 39: 2515-24. PMID 11044723 DOI: 10.1016/S0028-3908(00)00124-6  0.409
2000 Lioudyno MI, Verbitsky M, Holt JC, Elgoyhen AB, Guth PS. Morphine inhibits an alpha9-acetylcholine nicotinic receptor-mediated response by a mechanism which does not involve opioid receptors. Hearing Research. 149: 167-77. PMID 11033256 DOI: 10.1016/S0378-5955(00)00180-5  0.387
2000 Katz E, Verbitsky M, Rothlin CV, Vetter DE, Heinemann SF, Elgoyhen AB. High calcium permeability and calcium block of the alpha9 nicotinic acetylcholine receptor. Hearing Research. 141: 117-28. PMID 10713500 DOI: 10.1016/S0378-5955(99)00214-2  0.402
1999 Vetter DE, Liberman MC, Mann J, Barhanin J, Boulter J, Brown MC, Saffiote-Kolman J, Heinemann SF, Elgoyhen AB. Role of alpha9 nicotinic ACh receptor subunits in the development and function of cochlear efferent innervation. Neuron. 23: 93-103. PMID 10402196 DOI: 10.1016/S0896-6273(00)80756-4  0.378
1999 Rothlin CV, Katz E, Verbitsky M, Elgoyhen AB. The alpha9 nicotinic acetylcholine receptor shares pharmacological properties with type A gamma-aminobutyric acid, glycine, and type 3 serotonin receptors. Molecular Pharmacology. 55: 248-54. PMID 9927615  0.405
1998 Morley BJ, Li HS, Hiel H, Drescher DG, Elgoyhen AB. Identification of the subunits of the nicotinic cholinergic receptors in the rat cochlea using RT-PCR and in situ hybridization. Brain Research. Molecular Brain Research. 53: 78-87. PMID 9473597 DOI: 10.1016/S0169-328X(97)00272-6  0.456
1996 Hiel H, Elgoyhen AB, Drescher DG, Morley BJ. Expression of nicotinic acetylcholine receptor mRNA in the adult rat peripheral vestibular system. Brain Research. 738: 347-52. PMID 8955534 DOI: 10.1016/S0006-8993(96)01046-3  0.356
1994 Chini B, Raimond E, Elgoyhen AB, Moralli D, Balzaretti M, Heinemann S. Molecular cloning and chromosomal localization of the human alpha 7-nicotinic receptor subunit gene (CHRNA7). Genomics. 19: 379-81. PMID 8188270 DOI: 10.1006/Geno.1994.1075  0.424
1994 Elgoyhen AB, Johnson DS, Boulter J, Vetter DE, Heinemann S. Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell. 79: 705-15. PMID 7954834 DOI: 10.1016/0092-8674(94)90555-X  0.507
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