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Year Citation  Score
2020 Do C, Dumont ELP, Salas M, Castano A, Mujahed H, Maldonado L, Singh A, DaSilva-Arnold SC, Bhagat G, Lehman S, Christiano AM, Madhavan S, Nagy PL, Green PHR, Feinman R, ... ... Tycko B, et al. Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs. Genome Biology. 21: 153. PMID 32594908 DOI: 10.1186/S13059-020-02059-3  0.338
2020 Yu YE, Xing Z, Do C, Pao A, Lee EJ, Krinsky-McHale S, Silverman W, Schupf N, Tycko B. Genetic and epigenetic pathways in Down syndrome: Insights to the brain and immune system from humans and mouse models. Progress in Brain Research. 251: 1-28. PMID 32057305 DOI: 10.1016/Bs.Pbr.2019.09.002  0.365
2018 Delahaye F, Do C, Kong Y, Ashkar R, Salas M, Tycko B, Wapner R, Hughes F. Genetic variants influence on the placenta regulatory landscape. Plos Genetics. 14: e1007785. PMID 30452450 DOI: 10.1371/Journal.Pgen.1007785  0.359
2018 Wu HC, Do C, Andrulis IL, John EM, Daly MB, Buys SS, Chung WK, Knight JA, Bradbury AR, Keegan THM, Schwartz L, Krupska I, Miller RL, Santella RM, Tycko B, et al. Breast Cancer Family History and Allele-Specific DNA Methylation in the Legacy Girls Study. Epigenetics. 1-23. PMID 29436922 DOI: 10.1080/15592294.2018.1435243  0.34
2017 Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, ... ... Tycko B, et al. The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nature Genetics. PMID 28671686 DOI: 10.1038/Ng.3906  0.317
2017 Do C, Shearer A, Suzuki M, Terry MB, Gelernter J, Greally JM, Tycko B. Genetic-epigenetic interactions in cis: a major focus in the post-GWAS era. Genome Biology. 18: 120. PMID 28629478 DOI: 10.1186/S13059-017-1250-Y  0.328
2017 Lee JH, Lee AJ, Dang LH, Pang D, Kisselev S, Krinsky-McHale SJ, Zigman WB, Luchsinger JA, Silverman W, Tycko B, Clark LN, Schupf N. Candidate gene analysis for Alzheimer's disease in adults with Down syndrome. Neurobiology of Aging. PMID 28554490 DOI: 10.1016/J.Neurobiolaging.2017.04.018  0.366
2017 Yotova I, Hsu E, Do C, Gaba A, Sczabolcs M, Dekan S, Kenner L, Wenzl R, Tycko B. Epigenetic Alterations Affecting Transcription Factors and Signaling Pathways in Stromal Cells of Endometriosis. Plos One. 12: e0170859. PMID 28125717 DOI: 10.1371/Journal.Pone.0170859  0.361
2016 Do C, Xing Z, Yu YE, Tycko B. Trans-acting epigenetic effects of chromosomal aneuploidies: lessons from Down syndrome and mouse models. Epigenomics. PMID 27911079 DOI: 10.2217/Epi-2016-0138  0.349
2016 Mendioroz M, Do C, Jiang X, Liu C, Darbary HK, Lang CF, Lin J, Thomas A, Abu-Amero S, Stanier P, Temkin A, Yale A, Liu MM, Li Y, Salas M, ... ... Tycko B, et al. Erratum to: Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models. Genome Biology. 17: 123. PMID 27282916 DOI: 10.1186/S13059-016-0949-5  0.31
2016 Do C, Lang CF, Lin J, Darbary H, Krupska I, Gaba A, Petukhova L, Vonsattel JP, Gallagher MP, Goland RS, Clynes RA, Dwork A, Kral JG, Monk C, Christiano AM, ... Tycko B, et al. Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation. American Journal of Human Genetics. 98: 934-55. PMID 27153397 DOI: 10.1016/J.Ajhg.2016.03.027  0.348
2016 Monk C, Feng T, Lee S, Krupska I, Champagne FA, Tycko B. Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior. The American Journal of Psychiatry. appiajp201515091171. PMID 27013342 DOI: 10.1176/Appi.Ajp.2015.15091171  0.305
2015 Mendioroz M, Do C, Jiang X, Liu C, Darbary HK, Lang CF, Lin J, Thomas A, Abu-Amero S, Stanier P, Temkin A, Yale A, Liu MM, Li Y, Salas M, ... ... Tycko B, et al. Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models. Genome Biology. 16: 263. PMID 26607552 DOI: 10.1186/S13059-015-0827-6  0.363
2015 Schupf N, Lee A, Park N, Dang LH, Pang D, Yale A, Oh DK, Krinsky-McHale SJ, Jenkins EC, Luchsinger JA, Zigman WB, Silverman W, Tycko B, Kisselev S, Clark L, et al. Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome. Neurobiology of Aging. PMID 26166206 DOI: 10.1016/J.Neurobiolaging.2015.06.020  0.335
2015 Hartley D, Blumenthal T, Carrillo M, DiPaolo G, Esralew L, Gardiner K, Granholm AC, Iqbal K, Krams M, Lemere C, Lott I, Mobley W, Ness S, Nixon R, Potter H, ... ... Tycko B, et al. Down syndrome and Alzheimer's disease: Common pathways, common goals. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 700-9. PMID 25510383 DOI: 10.1016/J.Jalz.2014.10.007  0.301
2014 Ohki R, Saito K, Chen Y, Kawase T, Hiraoka N, Saigawa R, Minegishi M, Aita Y, Yanai G, Shimizu H, Yachida S, Sakata N, Doi R, Kosuge T, Shimada K, ... Tycko B, et al. PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors. Proceedings of the National Academy of Sciences of the United States of America. 111: E2404-13. PMID 24912192 DOI: 10.1073/Pnas.1319962111  0.313
2013 Paliwal A, Temkin AM, Kerkel K, Yale A, Yotova I, Drost N, Lax S, Nhan-Chang CL, Powell C, Borczuk A, Aviv A, Wapner R, Chen X, Nagy PL, Schork N, ... ... Tycko B, et al. Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation. Plos Genetics. 9: e1003622. PMID 24009515 DOI: 10.1371/Journal.Pgen.1003622  0.354
2013 Narayan G, Xie D, Freddy AJ, Ishdorj G, Do C, Satwani P, Liyanage H, Clark L, Kisselev S, Nandula SV, Scotto L, Alobeid B, Savage D, Tycko B, O'Connor OA, et al. PCDH10 promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis. Genes, Chromosomes & Cancer. 52: 1030-41. PMID 23929756 DOI: 10.1002/Gcc.22098  0.328
2013 Shakya R, Gonda T, Quante M, Salas M, Kim S, Brooks J, Hirsch S, Davies J, Cullo A, Olive K, Wang TC, Szabolcs M, Tycko B, Ludwig T. Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma. Cancer Research. 73: 885-96. PMID 23204224 DOI: 10.1158/0008-5472.Can-12-1880  0.319
2013 Xing L, Salas M, Zhang H, Gittler J, Ludwig T, Lin CS, Murty VV, Silverman W, Arancio O, Tycko B. Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1). Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 30-43. PMID 23096997 DOI: 10.1007/S00335-012-9436-9  0.317
2013 Tycko B. Abstract ED02-02: Interaction between genetics, epigenetics, and environment in cancer prevention Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Ed02-02  0.336
2013 Lee S, Galili N, Nimer S, Minden MD, Murty VV, Jhanwar S, Raza A, Tycko B. Abstract 2989: Loss of methylation in a regulatory region of BCL2 in MDS/AML. Cancer Research. 73: 2989-2989. DOI: 10.1158/1538-7445.Am2013-2989  0.326
2012 Lee JH, Gurney S, Pang D, Temkin A, Park N, Janicki SC, Zigman WB, Silverman W, Tycko B, Schupf N. Polymorphisms in HSD17B1: Early Onset and Increased Risk of Alzheimer's Disease in Women with Down Syndrome. Current Gerontology and Geriatrics Research. 2012: 361218. PMID 22474448 DOI: 10.1155/2012/361218  0.31
2012 Gonda TA, Kim YI, Salas MC, Gamble MV, Shibata W, Muthupalani S, Sohn KJ, Abrams JA, Fox JG, Wang TC, Tycko B. Folic acid increases global DNA methylation and reduces inflammation to prevent Helicobacter-associated gastric cancer in mice. Gastroenterology. 142: 824-833.e7. PMID 22248660 DOI: 10.1053/J.Gastro.2011.12.058  0.304
2012 Chace C, Pang D, Weng C, Temkin A, Lax S, Silverman W, Zigman W, Ferin M, Lee JH, Tycko B, Schupf N. Variants in CYP17 and CYP19 cytochrome P450 genes are associated with onset of Alzheimer's disease in women with down syndrome. Journal of Alzheimer's Disease : Jad. 28: 601-12. PMID 22057025 DOI: 10.3233/Jad-2011-110860  0.323
2011 Zhao Q, Lee JH, Pang D, Temkin A, Park N, Janicki SC, Zigman WB, Silverman W, Tycko B, Schupf N. Estrogen receptor-Beta variants are associated with increased risk of Alzheimer's disease in women with down syndrome. Dementia and Geriatric Cognitive Disorders. 32: 241-9. PMID 22156442 DOI: 10.1159/000334522  0.313
2011 Kalac M, Scotto L, Marchi E, Amengual J, Seshan VE, Bhagat G, Ulahannan N, Leshchenko VV, Temkin AM, Parekh S, Tycko B, O'Connor OA. HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL. Blood. 118: 5506-16. PMID 21772049 DOI: 10.1182/Blood-2011-02-336891  0.336
2010 Kerkel K, Schupf N, Hatta K, Pang D, Salas M, Kratz A, Minden M, Murty V, Zigman WB, Mayeux RP, Jenkins EC, Torkamani A, Schork NJ, Silverman W, Croy BA, ... Tycko B, et al. Altered DNA methylation in leukocytes with trisomy 21. Plos Genetics. 6: e1001212. PMID 21124956 DOI: 10.1371/Journal.Pgen.1001212  0.376
2010 Tycko B. Allele-specific DNA methylation: beyond imprinting. Human Molecular Genetics. 19: R210-20. PMID 20855472 DOI: 10.1093/Hmg/Ddq376  0.375
2010 Xin Y, Chanrion B, Liu MM, Galfalvy H, Costa R, Ilievski B, Rosoklija G, Arango V, Dwork AJ, Mann JJ, Tycko B, Haghighi F. Genome-wide divergence of DNA methylation marks in cerebral and cerebellar cortices. Plos One. 5: e11357. PMID 20596539 DOI: 10.1371/Journal.Pone.0011357  0.313
2010 Tycko B. Mapping allele-specific DNA methylation: a new tool for maximizing information from GWAS. American Journal of Human Genetics. 86: 109-12. PMID 20159108 DOI: 10.1016/J.Ajhg.2010.01.021  0.356
2010 Kalac M, Marchi E, Scotto L, Amengual J, Seshan V, Bhagat G, Ulahannan N, Leshchenko V, Parekh S, Tycko B, O'Connor OA. Synergistic Combinations of Histone Deacetylase Inhibitors and Decitabine Induce a Unique Gene Expression and Epigenetic Profile In Models of Diffuse Large B-Cell Lymphoma Blood. 116: 435-435. DOI: 10.1182/Blood.V116.21.435.435  0.348
2010 Lee JH, Chace C, Cheng R, Pang D, Cheng C, Oh KT, Silverman W, Zigman W, Tycko B, Schupf N. Variants in the CYP17 Cytochrome P450 gene are associated with dementia onset and risk of Alzheimer's disease in women with Down syndrome Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.642  0.316
2009 Zuo T, Tycko B, Liu TM, Lin JJ, Huang TH. Methods in DNA methylation profiling. Epigenomics. 1: 331-45. PMID 20526417 DOI: 10.2217/Epi.09.31  0.303
2008 Jiang L, Gonda TA, Gamble MV, Salas M, Seshan V, Tu S, Twaddell WS, Hegyi P, Lazar G, Steele I, Varro A, Wang TC, Tycko B. Global hypomethylation of genomic DNA in cancer-associated myofibroblasts. Cancer Research. 68: 9900-8. PMID 19047171 DOI: 10.1158/0008-5472.Can-08-1319  0.331
2008 Kerkel K, Spadola A, Yuan E, Kosek J, Jiang L, Hod E, Li K, Murty VV, Schupf N, Vilain E, Morris M, Haghighi F, Tycko B. Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation. Nature Genetics. 40: 904-8. PMID 18568024 DOI: 10.1038/Ng.174  0.347
2008 Schupf N, Lee JH, Wei M, Pang D, Chace C, Cheng R, Zigman WB, Tycko B, Silverman W. Estrogen receptor-alpha variants increase risk of Alzheimer's disease in women with Down syndrome. Dementia and Geriatric Cognitive Disorders. 25: 476-82. PMID 18408366 DOI: 10.1159/000126495  0.333
2008 Kim MK, Mason JM, Li CM, Berkofsky-Fessler W, Jiang L, Choubey D, Grundy PE, Tycko B, Licht JD. A pathologic link between Wilms tumor suppressor gene, WT1, and IFI16. Neoplasia (New York, N.Y.). 10: 69-78. PMID 18231640 DOI: 10.1593/Neo.07869  0.31
2007 Xing L, Salas M, Lin CS, Zigman W, Silverman W, Subramaniyam S, Murty VV, Tycko B. Faithful tissue-specific expression of the human chromosome 21-linked COL6A1 gene in BAC-transgenic mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 113-22. PMID 17334655 DOI: 10.1007/S00335-006-0082-Y  0.329
2007 Kim HS, Roh CR, Chen B, Tycko B, Nelson DM, Sadovsky Y. Hypoxia regulates the expression of PHLDA2 in primary term human trophoblasts. Placenta. 28: 77-84. PMID 16584773 DOI: 10.1016/J.Placenta.2006.01.025  0.322
2006 Yuan E, Haghighi F, White S, Costa R, McMinn J, Chun K, Minden M, Tycko B. A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: validation in decitabine therapy and tumor/normal comparisons. Cancer Research. 66: 3443-51. PMID 16585166 DOI: 10.1158/0008-5472.Can-05-3739  0.335
2006 Tycko B. Imprinted genes in placental growth and obstetric disorders. Cytogenetic and Genome Research. 113: 271-8. PMID 16575190 DOI: 10.1159/000090842  0.353
2006 Li CM, Guo M, Salas M, Schupf N, Silverman W, Zigman WB, Husain S, Warburton D, Thaker H, Tycko B. Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21. Bmc Medical Genetics. 7: 24. PMID 16539728 DOI: 10.1186/1471-2350-7-24  0.324
2006 Li CM, Margolin AA, Salas M, Memeo L, Mansukhani M, Hibshoosh H, Szabolcs M, Klinakis A, Tycko B. PEG10 is a c-MYC target gene in cancer cells. Cancer Research. 66: 665-72. PMID 16423995 DOI: 10.1158/0008-5472.Can-05-1553  0.315
2006 McMinn J, Wei M, Sadovsky Y, Thaker HM, Tycko B. Imprinting of PEG1/MEST isoform 2 in human placenta. Placenta. 27: 119-26. PMID 16338457 DOI: 10.1016/J.Placenta.2004.12.003  0.353
2006 McMinn J, Wei M, Schupf N, Cusmai J, Johnson EB, Smith AC, Weksberg R, Thaker HM, Tycko B. Unbalanced placental expression of imprinted genes in human intrauterine growth restriction. Placenta. 27: 540-9. PMID 16125225 DOI: 10.1016/J.Placenta.2005.07.004  0.347
2005 Yuan E, Li CM, Yamashiro DJ, Kandel J, Thaker H, Murty VV, Tycko B. Genomic profiling maps loss of heterozygosity and defines the timing and stage dependence of epigenetic and genetic events in Wilms' tumors. Molecular Cancer Research : McR. 3: 493-502. PMID 16179496 DOI: 10.1158/1541-7786.Mcr-05-0082  0.315
2005 Jakob J, Nagase S, Gazdar A, Chien M, Morozova I, Russo JJ, Nandula SV, Murty VV, Li CM, Tycko B, Parsons R. Two somatic biallelic lesions within and near SMAD4 in a human breast cancer cell line. Genes, Chromosomes & Cancer. 42: 372-83. PMID 15645498 DOI: 10.1002/Gcc.20142  0.316
2004 Tycko B, Lee JH, Ciappa A, Saxena A, Li CM, Feng L, Arriaga A, Stern Y, Lantigua R, Shachter N, Mayeux R. APOE and APOC1 promoter polymorphisms and the risk of Alzheimer disease in African American and Caribbean Hispanic individuals. Archives of Neurology. 61: 1434-9. PMID 15364690 DOI: 10.1001/Archneur.61.9.1434  0.32
2004 Salas M, John R, Saxena A, Barton S, Frank D, Fitzpatrick G, Higgins MJ, Tycko B. Placental growth retardation due to loss of imprinting of Phlda2. Mechanisms of Development. 121: 1199-210. PMID 15327781 DOI: 10.1016/J.Mod.2004.05.017  0.333
2004 Li Q, Athan ES, Wei M, Yuan E, Rice SL, Vonsattel JP, Mayeux RP, Tycko B. TP73 allelic expression in human brain and allele frequencies in Alzheimer's disease. Bmc Medical Genetics. 5: 14. PMID 15175114 DOI: 10.1186/1471-2350-5-14  0.346
2003 Tycko B. Genetic and epigenetic mosaicism in cancer precursor tissues. Annals of the New York Academy of Sciences. 983: 43-54. PMID 12724211 DOI: 10.1111/J.1749-6632.2003.Tb05961.X  0.309
2003 Goldberg M, Wei M, Yuan L, Murty VV, Tycko B. Biallelic expression of HRAS and MUCDHL in human and mouse. Human Genetics. 112: 334-42. PMID 12589428 DOI: 10.1007/S00439-003-0907-7  0.384
2002 Athan ES, Lee JH, Arriaga A, Mayeux RP, Tycko B. Polymorphisms in the promoter of the human APP gene: functional evaluation and allele frequencies in Alzheimer disease. Archives of Neurology. 59: 1793-9. PMID 12433268 DOI: 10.1001/Archneur.59.11.1793  0.337
2002 Lynch CA, Tycko B, Bestor TH, Walsh CP. Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation. Molecular Cancer. 1: 2. PMID 12234381 DOI: 10.1186/1476-4598-1-2  0.344
2002 Yeh A, Wei M, Golub SB, Yamashiro DJ, Murty VV, Tycko B. Chromosome arm 16q in Wilms tumors: unbalanced chromosomal translocations, loss of heterozygosity, and assessment of the CTCF gene. Genes, Chromosomes & Cancer. 35: 156-63. PMID 12203779 DOI: 10.1002/Gcc.10110  0.344
2002 Goldberg M, Wei M, Tycko B, Falikovich I, Warburton D. Identification and expression analysis of the human mu-protocadherin gene in fetal and adult kidneys. American Journal of Physiology. Renal Physiology. 283: F454-63. PMID 12167596 DOI: 10.1152/Ajprenal.00012.2002  0.307
2002 Tycko B, Morison IM. Physiological functions of imprinted genes. Journal of Cellular Physiology. 192: 245-58. PMID 12124770 DOI: 10.1002/Jcp.10129  0.331
2002 Clark L, Wei M, Cattoretti G, Mendelsohn C, Tycko B. The Tnfrh1 (Tnfrsf23) gene is weakly imprinted in several organs and expressed at the trophoblast-decidua interface. Bmc Genetics. 3: 11. PMID 12102730 DOI: 10.1186/1471-2156-3-11  0.337
2002 Li CM, Guo M, Borczuk A, Powell CA, Wei M, Thaker HM, Friedman R, Klein U, Tycko B. Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition. The American Journal of Pathology. 160: 2181-90. PMID 12057921 DOI: 10.1016/S0002-9440(10)61166-2  0.327
2002 Frank D, Fortino W, Clark L, Musalo R, Wang W, Saxena A, Li CM, Reik W, Ludwig T, Tycko B. Placental overgrowth in mice lacking the imprinted gene Ipl. Proceedings of the National Academy of Sciences of the United States of America. 99: 7490-5. PMID 12032310 DOI: 10.1073/Pnas.122039999  0.331
2001 Athan ES, Williamson J, Ciappa A, Santana V, Romas SN, Lee JH, Rondon H, Lantigua RA, Medrano M, Torres M, Arawaka S, Rogaeva E, Song YQ, Sato C, Kawarai T, ... ... Tycko B, et al. A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families. Jama. 286: 2257-63. PMID 11710891 DOI: 10.1001/Jama.286.18.2257  0.305
2001 Sakatani T, Wei M, Katoh M, Okita C, Wada D, Mitsuya K, Meguro M, Ikeguchi M, Ito H, Tycko B, Oshimura M. Epigenetic heterogeneity at imprinted loci in normal populations. Biochemical and Biophysical Research Communications. 283: 1124-30. PMID 11355889 DOI: 10.1006/Bbrc.2001.4916  0.353
2000 Romas SN, Mayeux R, Rabinowitz D, Tang MX, Zadroga HR, Lantigua R, Medrano M, Tycko B, Knowles JA. The deletion polymorphism and Val1000Ile in alpha-2-macroglobulin and Alzheimer disease in Caribbean Hispanics. Neuroscience Letters. 279: 133-6. PMID 10688047 DOI: 10.1016/S0304-3940(99)00972-6  0.305
2000 Tycko B. Epigenetic gene silencing in cancer. The Journal of Clinical Investigation. 105: 401-7. PMID 10683367 DOI: 10.1172/Jci9462  0.365
2000 Tycko B, Ashkenas J. Epigenetics and its role in disease. The Journal of Clinical Investigation. 105: 245-6. PMID 10675348 DOI: 10.1172/Jci9319  0.402
1999 Frank D, Mendelsohn CL, Ciccone E, Svensson K, Ohlsson R, Tycko B. A novel pleckstrin homology-related gene family defined by Ipl/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprinting. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 10: 1150-9. PMID 10594239 DOI: 10.1007/S003359901182  0.356
1999 Dao D, Walsh CP, Yuan L, Gorelov D, Feng L, Hensle T, Nisen P, Yamashiro DJ, Bestor TH, Tycko B. Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting. Human Molecular Genetics. 8: 1337-52. PMID 10369881 DOI: 10.1093/Hmg/8.7.1337  0.364
1998 Schupf N, Kapell D, Nightingale B, Rodriguez A, Tycko B, Mayeux R. Earlier onset of Alzheimer's disease in men with Down syndrome Neurology. 50: 991-995. PMID 9566384 DOI: 10.1212/Wnl.50.4.991  0.31
1998 Dao D, Frank D, Qian N, O'Keefe D, Vosatka RJ, Walsh CP, Tycko B. IMPT1, an imprinted gene similar to polyspecific transporter and multi-drug resistance genes. Human Molecular Genetics. 7: 597-608. PMID 9499412 DOI: 10.1093/Hmg/7.4.597  0.351
1997 Isfort RJ, Cody DB, Kerckaert GA, Tycko B, LeBoeuf RA. Role of the H19 gene in Syrian hamster embryo cell tumorigenicity. Molecular Carcinogenesis. 20: 189-93. PMID 9364208 DOI: 10.1002/(Sici)1098-2744(199710)20:2<189::Aid-Mc5>3.0.Co;2-I  0.322
1997 Qian N, Frank D, O'Keefe D, Dao D, Zhao L, Yuan L, Wang Q, Keating M, Walsh C, Tycko B. The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis. Human Molecular Genetics. 6: 2021-9. PMID 9328465 DOI: 10.1093/Hmg/6.12.2021  0.366
1997 O'Keefe D, Dao D, Zhao L, Sanderson R, Warburton D, Weiss L, Anyane-Yeboa K, Tycko B. Coding mutations in p57(KIP2) are present in some cases of Beckwith- Wiedemann syndrome but are rare or absent in Wilms tumors American Journal of Human Genetics. 61: 295-303. PMID 9311733 DOI: 10.1086/514854  0.32
1997 Tycko B. DNA methylation in genomic imprinting. Mutation Research. 386: 131-40. PMID 9113114 DOI: 10.1016/S1383-5742(96)00049-X  0.385
1997 Chung WY, Yuan L, Feng L, Hensle T, Tycko B. Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors. Human Molecular Genetics. 5: 1101-8. PMID 8842727 DOI: 10.1093/Hmg/5.8.1101  0.362
1996 Yuan L, Qian N, Tycko B. An extended region of biallelic gene expression and rodent-human synteny downstream of the imprinted H19 gene on chromosome 11p15.5. Human Molecular Genetics. 5: 1931-7. PMID 8968746 DOI: 10.1093/Hmg/5.12.1931  0.339
1996 Moulton T, Chung WY, Yuan L, Hensle T, Waber P, Nisen P, Tycko B. Genomic imprinting and Wilms' tumor. Medical and Pediatric Oncology. 27: 476-83. PMID 8827077 DOI: 10.1002/(Sici)1096-911X(199611)27:5<476::Aid-Mpo15>3.0.Co;2-8  0.36
1996 Tycko B, Feng L, Nguyen L, Francis A, Hays A, Chung WY, Tang MX, Stern Y, Sahota A, Hendrie H, Mayeux R. Polymorphisms in the human apolipoprotein-J/clusterin gene: ethnic variation and distribution in Alzheimer's disease. Human Genetics. 98: 430-6. PMID 8792817 DOI: 10.1007/S004390050234  0.327
1995 Tsang P, Gilles F, Yuan L, Kuo Y, Lupu F, Samara G, Moosikasuwan J, Goye A, Zelenetz AD, Selleri L, Tycko B. A novel L23-related gene 40 kb downstream of the imprinted H19 gene is biallelically expressed in mid-fetal and adult human tissues Human Molecular Genetics. 4: 1499-1507. PMID 8541832 DOI: 10.1093/Hmg/4.9.1499  0.354
1995 Maestre G, Ottman R, Stern Y, Gurland B, Chun M, Tang MX, Shelanski M, Tycko B, Mayeux R. Apolipoprotein E and Alzheimer's disease: Ethnic variation in genotypic risks Annals of Neurology. 37: 254-259. PMID 7847867 DOI: 10.1002/Ana.410370217  0.313
1993 Mayeux R, Stern Y, Ottman R, Tatemichi TK, Tang MX, Maestre G, Ngai C, Tycko B, Ginsberg H. The apolipoprotein epsilon 4 allele in patients with Alzheimer's disease. Annals of Neurology. 34: 752-4. PMID 8239575 DOI: 10.1002/Ana.410340527  0.308
1993 Hao Y, Crenshaw T, Moulton T, Newcomb E, Tycko B. Tumour-suppressor activity of H19 RNA. Nature. 365: 764-7. PMID 7692308 DOI: 10.1038/365764A0  0.338
1993 Zhang Y, Tycko B. Monoallelic expression of the human H19 gene. Nature Genetics. 1: 40-4. PMID 1363808 DOI: 10.1038/Ng0492-40  0.351
1984 DiPaola M, Keith CH, Feldman D, Tycko B, Maxfield FR. Loss of alpha 2-macroglobulin and epidermal growth factor surface binding induced by phenothiazines and naphthalene sulfonamides. Journal of Cellular Physiology. 118: 193-202. PMID 6319437 DOI: 10.1002/Jcp.1041180212  0.494
1984 Yamashiro DJ, Tycko B, Fluss SR, Maxfield FR. Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway. Cell. 37: 789-800. PMID 6204769 DOI: 10.1016/0092-8674(84)90414-8  0.483
1983 Tycko B, Keith CH, Maxfield FR. Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line. The Journal of Cell Biology. 97: 1762-76. PMID 6315742 DOI: 10.1083/Jcb.97.6.1762  0.49
1983 Tycko B, DiPaola M, Yamashiro DJ, Fluss S, Maxfield FR. Acidification of endocytic vesicles and the intracellular pathways of ligands and receptors. Annals of the New York Academy of Sciences. 421: 424-33. PMID 6202216 DOI: 10.1111/J.1749-6632.1983.Tb18136.X  0.463
1982 Tycko B, Maxfield FR. Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin. Cell. 28: 643-51. PMID 6176331 DOI: 10.1016/0092-8674(82)90219-7  0.474
1982 Anderson P, Tycko B, Maxfield F, Vilček J. Effect of primary amines on interferon action Virology. 117: 510-515. PMID 6175094 DOI: 10.1016/0042-6822(82)90491-3  0.494
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