Gregory Frolenkov - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
hair cells

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 El Najjar F, Castillo SR, Moncman CL, Wu CY, Isla E, Velez Ortega AC, Frolenkov GI, Cifuentes-Munoz N, Dutch RE. Imaging analysis reveals budding of filamentous human metapneumovirus virions and direct transfer of inclusion bodies through intercellular extensions. Mbio. e0158923. PMID 37681946 DOI: 10.1128/mbio.01589-23  0.344
2023 Aristizábal-Ramírez I, Dragich AK, Giese APJ, Sofia Zuluaga-Osorio K, Watkins J, Davies GK, Hadi SE, Riazuddin S, Vander Kooi CW, Ahmed ZM, Frolenkov GI. Calcium and Integrin-binding protein 2 (CIB2) controls force sensitivity of the mechanotransducer channels in cochlear outer hair cells. Biorxiv : the Preprint Server For Biology. PMID 37461484 DOI: 10.1101/2023.07.09.545606  0.335
2023 Moore ST, Nakamura T, Nie J, Solivais AJ, Aristizábal-Ramírez I, Ueda Y, Manikandan M, Reddy VS, Romano DR, Hoffman JR, Perrin BJ, Nelson RF, Frolenkov GI, Chuva de Sousa Lopes SM, Hashino E. Generating high-fidelity cochlear organoids from human pluripotent stem cells. Cell Stem Cell. 30: 950-961.e7. PMID 37419105 DOI: 10.1016/j.stem.2023.06.006  0.366
2023 Vélez-Ortega AC, Stepanyan R, Edelmann SE, Torres-Gallego S, Park C, Marinkova DA, Nowacki JS, Sinha GP, Frolenkov GI. TRPA1 activation in non-sensory supporting cells contributes to regulation of cochlear sensitivity after acoustic trauma. Nature Communications. 14: 3871. PMID 37391431 DOI: 10.1038/s41467-023-39589-w  0.801
2022 Babahosseini H, Belyantseva IA, Yousaf R, Tona R, Hadi S, Inagaki S, Wilson E, Kitajiri SI, Frolenkov GI, Friedman TB, Cartagena-Rivera AX. Unbalanced bidirectional radial stiffness gradients within the organ of Corti promoted by TRIOBP. Proceedings of the National Academy of Sciences of the United States of America. 119: e2115190119. PMID 35737845 DOI: 10.1073/pnas.2115190119  0.437
2021 Zamakhaeva S, Chaton CT, Rush JS, Ajay Castro S, Kenner CW, Yarawsky AE, Herr AB, van Sorge NM, Dorfmueller HC, Frolenkov GI, Korotkov KV, Korotkova N. Modification of cell wall polysaccharide guides cell division in Streptococcus mutans. Nature Chemical Biology. PMID 34045745 DOI: 10.1038/s41589-021-00803-9  0.335
2021 Galeano-Naranjo C, Veléz-Ortega AC, Frolenkov GI. Stereocilia Bundle Imaging with Nanoscale Resolution in Live Mammalian Auditory Hair Cells. Journal of Visualized Experiments : Jove. PMID 33554973 DOI: 10.3791/62104  0.829
2020 Hadi S, Alexander AJ, Vélez-Ortega AC, Frolenkov GI. Myosin-XVa Controls Both Staircase Architecture and Diameter Gradation of Stereocilia Rows in the Auditory Hair Cell Bundles. Journal of the Association For Research in Otolaryngology : Jaro. PMID 32152769 DOI: 10.1007/S10162-020-00745-4  0.809
2019 Katsuno T, Belyantseva IA, Cartagena-Rivera AX, Ohta K, Crump SM, Petralia RS, Ono K, Tona R, Imtiaz A, Rehman A, Kiyonari H, Kaneko M, Wang YX, Abe T, Ikeya M, ... ... Frolenkov GI, et al. TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing. Jci Insight. 4. PMID 31217345 DOI: 10.1172/jci.insight.128561  0.364
2019 Vélez-Ortega AC, Frolenkov GI. Building and repairing the stereocilia cytoskeleton in mammalian auditory hair cells. Hearing Research. PMID 30638948 DOI: 10.1016/J.Heares.2018.12.012  0.813
2018 Chessum L, Matern MS, Kelly MC, Johnson SL, Ogawa Y, Milon B, McMurray M, Driver EC, Parker A, Song Y, Codner G, Esapa CT, Prescott J, Trent G, Wells S, ... ... Frolenkov GI, et al. Helios is a key transcriptional regulator of outer hair cell maturation. Nature. PMID 30464345 DOI: 10.1038/S41586-018-0728-4  0.352
2017 Giese APJ, Tang YQ, Sinha GP, Bowl MR, Goldring AC, Parker A, Freeman MJ, Brown SDM, Riazuddin S, Fettiplace R, Schafer WR, Frolenkov GI, Ahmed ZM. CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells. Nature Communications. 8: 43. PMID 28663585 DOI: 10.1038/S41467-017-00061-1  0.372
2017 Vélez-Ortega AC, Freeman MJ, Indzhykulian AA, Grossheim JM, Frolenkov GI. Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells. Elife. 6. PMID 28350294 DOI: 10.7554/Elife.24661  0.787
2017 Vélez-Ortega AC, Frolenkov GI. Auditory Hair Cell Stereocilia The Hearing Journal. 70: 8. DOI: 10.1097/01.Hj.0000527208.28817.42  0.809
2016 Vélez-Ortega AC, Frolenkov GI. Visualization of Live Cochlear Stereocilia at a Nanoscale Resolution Using Hopping Probe Ion Conductance Microscopy. Methods in Molecular Biology (Clifton, N.J.). 1427: 203-21. PMID 27259929 DOI: 10.1007/978-1-4939-3615-1_12  0.83
2016 Shevchuk A, Tokar S, Gopal S, Sanchez-Alonso JL, Tarasov AI, Vélez-Ortega AC, Chiappini C, Rorsman P, Stevens MM, Gorelik J, Frolenkov GI, Klenerman D, Korchev YE. Angular Approach Scanning Ion Conductance Microscopy. Biophysical Journal. 110: 2252-2265. PMID 27224490 DOI: 10.1016/J.Bpj.2016.04.017  0.801
2016 Velez-Ortega AC, Belov O, Novak P, Rawashdeh SA, Korchev YE, Frolenkov GI. Adaptive Hopping Probe Ion Conductance Microscopy of Live Cells at ∼5-10 NM Resolution Biophysical Journal. 110: 517a. DOI: 10.1016/J.Bpj.2015.11.2764  0.805
2015 Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, ... ... Frolenkov GI, et al. RFX transcription factors are essential for hearing in mice. Nature Communications. 6: 8549. PMID 26469318 DOI: 10.1038/Ncomms9549  0.355
2015 Fang Q, Indzhykulian AA, Mustapha M, Riordan GP, Dolan DF, Friedman TB, Belyantseva IA, Frolenkov GI, Camper SA, Bird JE. The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing. Elife. 4. PMID 26302205 DOI: 10.7554/Elife.08627  0.738
2014 Vélez-Ortega AC, Belov O, Novak P, Rawashdeh SA, Sinha GP, Korchev YE, Frolenkov GI. High-Speed Hopping Probe Scanning Ion Conductance Microscopy Biophysical Journal. 106: 797a-798a. DOI: 10.1016/J.Bpj.2013.11.4374  0.828
2013 Nayak G, Lee SI, Yousaf R, Edelmann SE, Trincot C, Van Itallie CM, Sinha GP, Rafeeq M, Jones SM, Belyantseva IA, Anderson JM, Forge A, Frolenkov GI, Riazuddin S. Tricellulin deficiency affects tight junction architecture and cochlear hair cells. The Journal of Clinical Investigation. 123: 4036-49. PMID 23979167 DOI: 10.1172/Jci69031  0.35
2013 Indzhykulian AA, Stepanyan R, Nelina A, Spinelli KJ, Ahmed ZM, Belyantseva IA, Friedman TB, Barr-Gillespie PG, Frolenkov GI. Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells. Plos Biology. 11: e1001583. PMID 23776407 DOI: 10.1371/Journal.Pbio.1001583  0.827
2012 Szarama KB, Stepanyan R, Petralia RS, Gavara N, Frolenkov GI, Kelley MW, Chadwick RS. Fibroblast growth factor receptor 3 regulates microtubule formation and cell surface mechanical properties in the developing organ of Corti. Bioarchitecture. 2: 214-9. PMID 23267415 DOI: 10.4161/bioa.22332  0.748
2012 Riazuddin S, Belyantseva IA, Giese AP, Lee K, Indzhykulian AA, Nandamuri SP, Yousaf R, Sinha GP, Lee S, Terrell D, Hegde RS, Ali RA, Anwar S, Andrade-Elizondo PB, Sirmaci A, ... ... Frolenkov GI, et al. Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48. Nature Genetics. 44: 1265-71. PMID 23023331 DOI: 10.1038/Ng.2426  0.7
2012 Velez-Ortega AC, Indzhykulian AA, Sinha GP, Frolenkov GI. Imaging Stereocilia Links in Live Auditory Hair Cells Biophysical Journal. 102: 655a. DOI: 10.1016/J.Bpj.2011.11.3567  0.795
2011 Stepanyan RS, Indzhykulian AA, Vélez-Ortega AC, Boger ET, Steyger PS, Friedman TB, Frolenkov GI. TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells. Journal of the Association For Research in Otolaryngology : Jaro. 12: 729-40. PMID 21879401 DOI: 10.1007/S10162-011-0288-X  0.804
2010 Kitajiri S, Sakamoto T, Belyantseva IA, Goodyear RJ, Stepanyan R, Fujiwara I, Bird JE, Riazuddin S, Riazuddin S, Ahmed ZM, Hinshaw JE, Sellers J, Bartles JR, Hammer JA, Richardson GP, ... ... Frolenkov GI, et al. Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing. Cell. 141: 786-98. PMID 20510926 DOI: 10.1016/J.Cell.2010.03.049  0.778
2009 Belyantseva IA, Perrin BJ, Sonnemann KJ, Zhu M, Stepanyan R, McGee J, Frolenkov GI, Walsh EJ, Friderici KH, Friedman TB, Ervasti JM. Gamma-actin is required for cytoskeletal maintenance but not development. Proceedings of the National Academy of Sciences of the United States of America. 106: 9703-8. PMID 19497859 DOI: 10.1073/Pnas.0900221106  0.749
2009 Stepanyan R, Frolenkov GI. Fast adaptation and Ca2+ sensitivity of the mechanotransducer require myosin-XVa in inner but not outer cochlear hair cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4023-34. PMID 19339598 DOI: 10.1523/JNEUROSCI.4566-08.2009  0.805
2009 Novak P, Li C, Shevchuk AI, Stepanyan R, Caldwell M, Hughes S, Smart TG, Gorelik J, Ostanin VP, Lab MJ, Moss GW, Frolenkov GI, Klenerman D, Korchev YE. Nanoscale live-cell imaging using hopping probe ion conductance microscopy. Nature Methods. 6: 279-81. PMID 19252505 DOI: 10.1038/Nmeth.1306  0.781
2009 Frolenkov GI. Ion imaging in the cochlear hair cells. Methods in Molecular Biology (Clifton, N.J.). 493: 381-99. PMID 18839360 DOI: 10.1007/978-1-59745-523-7_23  0.451
2009 Novak P, Li C, Shevchuk A, Stepanyan R, Caldwell M, Hughes S, Smart T, Gorelik J, Lab M, Moss G, Frolenkov G, Klenerman D, Korchev Y. Next Generation SICM Allows Nanoscale Imaging Of Biological Processes In Real-time Biophysical Journal. 96: 374a. DOI: 10.1016/J.Bpj.2008.12.2811  0.49
2008 Sánchez D, Johnson N, Li C, Novak P, Rheinlaender J, Zhang Y, Anand U, Anand P, Gorelik J, Frolenkov GI, Benham C, Lab M, Ostanin VP, Schäffer TE, Klenerman D, et al. Noncontact measurement of the local mechanical properties of living cells using pressure applied via a pipette. Biophysical Journal. 95: 3017-27. PMID 18515369 DOI: 10.1529/Biophysj.108.129551  0.318
2006 Stepanyan R, Belyantseva IA, Griffith AJ, Friedman TB, Frolenkov GI. Auditory mechanotransduction in the absence of functional myosin-XVa. The Journal of Physiology. 576: 801-8. PMID 16973713 DOI: 10.1113/jphysiol.2006.118547  0.79
2006 Frolenkov GI. Regulation of electromotility in the cochlear outer hair cell. The Journal of Physiology. 576: 43-8. PMID 16887876 DOI: 10.1113/jphysiol.2006.114975  0.44
2006 Ahmed ZM, Goodyear R, Riazuddin S, Lagziel A, Legan PK, Behra M, Burgess SM, Lilley KS, Wilcox ER, Riazuddin S, Griffith AJ, Frolenkov GI, Belyantseva IA, Richardson GP, Friedman TB. The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7022-34. PMID 16807332 DOI: 10.1523/JNEUROSCI.1163-06.2006  0.343
2006 Noguchi Y, Kurima K, Makishima T, de Angelis MH, Fuchs H, Frolenkov G, Kitamura K, Griffith AJ. Multiple quantitative trait loci modify cochlear hair cell degeneration in the Beethoven (Tmc1Bth) mouse model of progressive hearing loss DFNA36. Genetics. 173: 2111-9. PMID 16648588 DOI: 10.1534/Genetics.106.057372  0.493
2006 Shevchuk AI, Frolenkov GI, Sánchez D, James PS, Freedman N, Lab MJ, Jones R, Klenerman D, Korchev YE. Imaging proteins in membranes of living cells by high-resolution scanning ion conductance microscopy. Angewandte Chemie (International Ed. in English). 45: 2212-6. PMID 16506257 DOI: 10.1002/Anie.200503915  0.314
2005 Gorelik J, Zhang Y, Sánchez D, Shevchuk A, Frolenkov G, Lab M, Klenerman D, Edwards C, Korchev Y. Aldosterone acts via an ATP autocrine/paracrine system: the Edelman ATP hypothesis revisited. Proceedings of the National Academy of Sciences of the United States of America. 102: 15000-5. PMID 16230642 DOI: 10.1073/Pnas.0507008102  0.391
2005 Belyantseva IA, Boger ET, Naz S, Frolenkov GI, Sellers JR, Ahmed ZM, Griffith AJ, Friedman TB. Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia. Nature Cell Biology. 7: 148-56. PMID 15654330 DOI: 10.1038/Ncb1219  0.396
2004 Gow A, Davies C, Southwood CM, Frolenkov G, Chrustowski M, Ng L, Yamauchi D, Marcus DC, Kachar B. Deafness in Claudin 11-null mice reveals the critical contribution of basal cell tight junctions to stria vascularis function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7051-62. PMID 15306639 DOI: 10.1523/Jneurosci.1640-04.2004  0.485
2004 Frolenkov GI, Belyantseva IA, Friedman TB, Griffith AJ. Genetic insights into the morphogenesis of inner ear hair cells. Nature Reviews. Genetics. 5: 489-98. PMID 15211351 DOI: 10.1038/nrg1377  0.328
2004 Gorelik J, Zhang Y, Shevchuk AI, Frolenkov GI, Sánchez D, Lab MJ, Vodyanoy I, Edwards CR, Klenerman D, Korchev YE. The use of scanning ion conductance microscopy to image A6 cells. Molecular and Cellular Endocrinology. 217: 101-8. PMID 15134807 DOI: 10.1016/J.Mce.2003.10.015  0.326
2003 Adler HJ, Belyantseva IA, Merritt RC, Frolenkov GI, Dougherty GW, Kachar B. Expression of prestin, a membrane motor protein, in the mammalian auditory and vestibular periphery. Hearing Research. 184: 27-40. PMID 14553901 DOI: 10.1016/S0378-5955(03)00192-8  0.376
2003 Gorelik J, Shevchuk AI, Frolenkov GI, Diakonov IA, Lab MJ, Kros CJ, Richardson GP, Vodyanoy I, Edwards CR, Klenerman D, Korchev YE. Dynamic assembly of surface structures in living cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 5819-22. PMID 12721367 DOI: 10.1073/Pnas.1030502100  0.305
1998 Frolenkov GI, Atzori M, Kalinec F, Mammano F, Kachar B. The membrane-based mechanism of cell motility in cochlear outer hair cells. Molecular Biology of the Cell. 9: 1961-8. PMID 9693359 DOI: 10.1091/Mbc.9.8.1961  0.309
1991 Khayutin VM, Sonina RS, Frolenkov GI, Zizin IM. Antidromic vasodilation in frog: identification of the nerve fiber types involved. Pflugers Archiv : European Journal of Physiology. 419: 508-13. PMID 1775374 DOI: 10.1007/Bf00370797  0.621
1990 Zizin IM, Frolenkov GI, Khayutin VM. Antidromic vasodilatation induced by A?-afferents in the frog Bulletin of Experimental Biology and Medicine. 110: 1153-1156. DOI: 10.1007/Bf00840266  0.606
1986 Frolenkov GI, Lukoshkova EV, Khayutin VM. Somato-sympathetic response with the extremely high latency in unanesthetized decerebrate frog. Journal of the Autonomic Nervous System. 16: 85-90. PMID 3486203 DOI: 10.1016/0165-1838(86)90053-6  0.624
1986 Frolenkov GI, Lukoshkova EV, Khayutin VM. Very long-latency somatosympathetic response in unanesthetized decerebrate frogs Bulletin of Experimental Biology and Medicine. 101: 1-3. DOI: 10.1007/BF00836056  0.613
1985 Frolenkov GI, Lukoshkova EV, Shuvalova TB, Khayutin VM. Arterial pressure responses to impulses in sciatic nerve a fibers in decerebrate and spinal frogs Bulletin of Experimental Biology and Medicine. 100: 1486-1488. DOI: 10.1007/BF00836141  0.598
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