Year |
Citation |
Score |
2023 |
Langenbacher AD, Lu F, Tsang L, Huang ZYS, Keer B, Tian Z, Eide A, Pellegrini M, Nakano H, Nakano A, Chen JN. Rtf1-dependent transcriptional pausing regulates cardiogenesis. Biorxiv : the Preprint Server For Biology. PMID 37873297 DOI: 10.1101/2023.10.13.562296 |
0.734 |
|
2023 |
Langenbacher AD, Lu F, Crisman L, Huang ZYS, Chapski DJ, Vondriska TM, Wang Y, Gao C, Chen JN. Rtf1 Transcriptionally Regulates Neonatal and Adult Cardiomyocyte Biology. Journal of Cardiovascular Development and Disease. 10. PMID 37233188 DOI: 10.3390/jcdd10050221 |
0.746 |
|
2021 |
Shimizu H, Huber S, Langenbacher AD, Crisman L, Huang J, Wang K, Wilting F, Gudermann T, Schredelseker J, Chen JN. Glutamate 73 Promotes Anti-arrhythmic Effects of Voltage-Dependent Anion Channel Through Regulation of Mitochondrial Ca Uptake. Frontiers in Physiology. 12: 724828. PMID 34483974 DOI: 10.3389/fphys.2021.724828 |
0.762 |
|
2020 |
Langenbacher AD, Shimizu H, Hsu W, Zhao Y, Borges A, Koehler C, Chen JN. Mitochondrial Calcium Uniporter Deficiency in Zebrafish Causes Cardiomyopathy With Arrhythmia. Frontiers in Physiology. 11: 617492. PMID 33424641 DOI: 10.3389/fphys.2020.617492 |
0.784 |
|
2020 |
Hilfenhaus G, Mompeón A, Freshman J, Prajapati D, Hernandez G, Freitas VM, Ma F, Langenbacher AD, Mirkov S, Song D, Cho BK, Goo YA, Pellegrini M, Chen JN, Damoiseaux R, et al. A high-content screen identifies drugs that restrict tumor cell extravasation across the endothelial barrier. Cancer Research. PMID 33218969 DOI: 10.1158/0008-5472.CAN-19-3911 |
0.657 |
|
2018 |
Xu Q, Dupper NJ, Smaligo AJ, Fan YC, Cai L, Wang Z, Langenbacher AD, Chen JN, Kwon O. Catalytic Enantioselective Synthesis of Guvacine Derivatives through [4 + 2] Annulations of Imines with α-Methylallenoates. Organic Letters. PMID 30246538 DOI: 10.1021/Acs.Orglett.8B02489 |
0.645 |
|
2018 |
Ding Y, Ma J, Langenbacher AD, Baek KI, Lee J, Chang CC, Hsu JJ, Kulkarni RP, Belperio J, Shi W, Ranjbarvaziri S, Ardehali R, Tintut Y, Demer LL, Chen JN, et al. Multiscale light-sheet for rapid imaging of cardiopulmonary system. Jci Insight. 3. PMID 30135307 DOI: 10.1172/Jci.Insight.121396 |
0.68 |
|
2018 |
Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen JN, Dupuy AJ, Iruela-Arispe ML. A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis. Cell Reports. 22: 1211-1224. PMID 29386109 DOI: 10.1016/J.Celrep.2018.01.017 |
0.774 |
|
2018 |
Chen J, Langenbacher AD, Lu F, Ren V, Wang Y, Gao C. Abstract 497: Rtf1 Regulates Cardiac Development and Function Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.497 |
0.749 |
|
2017 |
Shimizu H, Langenbacher AD, Huang J, Wang K, Otto G, Geisler R, Wang Y, Chen JN. The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes. Elife. 6. PMID 28826496 DOI: 10.7554/Elife.27955 |
0.788 |
|
2017 |
Shimizu H, Langenbacher AD, Huang J, Wang K, Otto G, Geisler R, Wang Y, Chen J. Author response: The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes Elife. DOI: 10.7554/Elife.27955.018 |
0.737 |
|
2016 |
Lu F, Langenbacher A, Chen JN. Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafish. Developmental Biology. PMID 27940156 DOI: 10.1016/J.Ydbio.2016.12.009 |
0.772 |
|
2016 |
Berchtold MW, Zacharias T, Kulej K, Wang K, Torggler R, Jespersen T, Chen JN, Larsen MR, La Cour JM. The Arrhythmogenic Calmodulin Mutation D129G Dysregulates Cell Growth, Calmodulin-dependent Kinase II Activity and Cardiac Function in Zebrafish. The Journal of Biological Chemistry. PMID 27815504 DOI: 10.1074/Jbc.M116.758680 |
0.435 |
|
2016 |
Lu F, Langenbacher AD, Chen JN. Transcriptional Regulation of Heart Development in Zebrafish. Journal of Cardiovascular Development and Disease. 3. PMID 27148546 DOI: 10.3390/Jcdd3020014 |
0.761 |
|
2015 |
Gao C, Ren S, Lee JH, Qiu J, Chapski DJ, Rau CD, Zhou Y, Abdellatif M, Nakano A, Vondriska TM, Xiao X, Fu XD, Chen JN, Wang Y. RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure. The Journal of Clinical Investigation. PMID 26619120 DOI: 10.1172/Jci84015 |
0.43 |
|
2015 |
Cavanaugh AM, Huang J, Chen JN. Two developmentally distinct populations of neural crest cells contribute to the zebrafish heart. Developmental Biology. 404: 103-12. PMID 26086691 DOI: 10.1016/J.Ydbio.2015.06.002 |
0.808 |
|
2015 |
Shimizu H, Schredelseker J, Huang J, Lu K, Naghdi S, Lu F, Franklin S, Fiji HD, Wang K, Zhu H, Tian C, Lin B, Nakano H, Ehrlich A, Nakai J, ... ... Chen JN, et al. Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity. Elife. 4. PMID 25588501 DOI: 10.7554/Elife.04801 |
0.775 |
|
2014 |
Lin C, Yao E, Wang K, Nozawa Y, Shimizu H, Johnson JR, Chen JN, Krogan NJ, Chuang PT. Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling. Genes & Development. 28: 2547-63. PMID 25403183 DOI: 10.1101/Gad.249425.114 |
0.57 |
|
2014 |
Li R, Beebe T, Jen N, Yu F, Takabe W, Harrison M, Cao H, Lee J, Yang H, Han P, Wang K, Shimizu H, Chen J, Lien CL, Chi NC, et al. Shear stress-activated Wnt-angiopoietin-2 signaling recapitulates vascular repair in zebrafish embryos. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2268-75. PMID 25147335 DOI: 10.1161/Atvbaha.114.303345 |
0.523 |
|
2014 |
Zhang Y, Shimizu H, Siu KL, Mahajan A, Chen JN, Cai H. NADPH oxidase 4 induces cardiac arrhythmic phenotype in zebrafish. The Journal of Biological Chemistry. 289: 23200-8. PMID 24962575 DOI: 10.1074/Jbc.M114.587196 |
0.631 |
|
2014 |
Schredelseker J, Paz A, López CJ, Altenbach C, Leung CS, Drexler MK, Chen JN, Hubbell WL, Abramson J. High resolution structure and double electron-electron resonance of the zebrafish voltage-dependent anion channel 2 reveal an oligomeric population. The Journal of Biological Chemistry. 289: 12566-77. PMID 24627492 DOI: 10.1074/Jbc.M113.497438 |
0.681 |
|
2014 |
Shimizu H, Schredelseker J, Huang J, Lu K, Naghdi S, Lu F, Franklin S, Fiji HD, Wang K, Zhu H, Tian C, Lin B, Nakano H, Ehrlich A, Nakai J, ... ... Chen J, et al. Author response: Mitochondrial Ca2+ uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity Elife. DOI: 10.7554/Elife.04801.030 |
0.774 |
|
2013 |
Monte E, Mouillesseaux K, Chen H, Kimball T, Ren S, Wang Y, Chen JN, Vondriska TM, Franklin S. Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1624-38. PMID 24077883 DOI: 10.1152/Ajpheart.00529.2013 |
0.781 |
|
2013 |
Foster WH, Langenbacher A, Gao C, Chen J, Wang Y. Nuclear phosphatase PPM1G in cellular survival and neural development Developmental Dynamics. 242: 1101-1109. PMID 23723158 DOI: 10.1002/Dvdy.23990 |
0.725 |
|
2012 |
Van Handel B, Montel-Hagen A, Sasidharan R, Nakano H, Ferrari R, Boogerd CJ, Schredelseker J, Wang Y, Hunter S, Org T, Zhou J, Li X, Pellegrini M, Chen JN, Orkin SH, et al. Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium. Cell. 150: 590-605. PMID 22863011 DOI: 10.1016/J.Cell.2012.06.026 |
0.753 |
|
2012 |
Langenbacher AD, Huang J, Chen Y, Chen JN. Sodium pump activity in the yolk syncytial layer regulates zebrafish heart tube morphogenesis. Developmental Biology. 362: 263-70. PMID 22182522 DOI: 10.1016/J.Ydbio.2011.12.004 |
0.765 |
|
2012 |
Schredelseker J, Shimizu H, Huang J, Lin BI, Chen J. Regulation of Voltage-Dependent Anion Channel 2 at Glutamate 73 is Critical for its Role in Cardiac Calcium Handling Biophysical Journal. 102: 312a. DOI: 10.1016/J.Bpj.2011.11.1720 |
0.801 |
|
2011 |
Mouillesseaux K, Chen JN. Mutation in utp15 disrupts vascular patterning in a p53-dependent manner in zebrafish embryos. Plos One. 6: e25013. PMID 21949834 DOI: 10.1371/Journal.Pone.0025013 |
0.775 |
|
2011 |
Langenbacher AD, Nguyen CT, Cavanaugh AM, Huang J, Lu F, Chen JN. The PAF1 complex differentially regulates cardiomyocyte specification. Developmental Biology. 353: 19-28. PMID 21338598 DOI: 10.1016/J.Ydbio.2011.02.011 |
0.803 |
|
2011 |
Choi J, Mouillesseaux K, Wang Z, Fiji HD, Kinderman SS, Otto GW, Geisler R, Kwon O, Chen JN. Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis. Development (Cambridge, England). 138: 1173-81. PMID 21307094 DOI: 10.1242/Dev.054049 |
0.769 |
|
2011 |
Schredelseker J, Huang J, Langenbacher A, Lu K, Kwon O, Goldhaber JI, Chen J. Identification of a Chemical Supressor of Cardiac Arrhythmia Induced by Aberrant Calcium Homeostasis Biophysical Journal. 100: 80a. DOI: 10.1016/J.Bpj.2010.12.645 |
0.802 |
|
2010 |
Nguyen CT, Langenbacher A, Hsieh M, Chen JN. The PAF1 complex component Leo1 is essential for cardiac and neural crest development in zebrafish. Developmental Biology. 341: 167-75. PMID 20178782 DOI: 10.1016/J.Ydbio.2010.02.020 |
0.784 |
|
2010 |
Langenbacher AD, Chen JN. Regulation of vertebrate left-right axis development by calcium Handbook of Cell Signaling, 2/E. 2: 1885-1890. DOI: 10.1016/B978-0-12-374145-5.00230-8 |
0.668 |
|
2009 |
Wilson CW, Nguyen CT, Chen MH, Yang JH, Gacayan R, Huang J, Chen JN, Chuang PT. Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis. Nature. 459: 98-102. PMID 19305393 DOI: 10.1038/Nature07883 |
0.501 |
|
2009 |
Colantonio JR, Vermot J, Wu D, Langenbacher AD, Fraser S, Chen JN, Hill KL. The dynein regulatory complex is required for ciliary motility and otolith biogenesis in the inner ear. Nature. 457: 205-9. PMID 19043402 DOI: 10.1038/Nature07520 |
0.667 |
|
2008 |
Nguyen CT, Lu Q, Wang Y, Chen JN. Zebrafish as a model for cardiovascular development and disease. Drug Discovery Today. Disease Models. 5: 135-140. PMID 22275951 DOI: 10.1016/J.Ddmod.2009.02.003 |
0.531 |
|
2008 |
Langenbacher A, Chen JN. Calcium signaling: a common thread in vertebrate left-right axis development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 3491-6. PMID 18792114 DOI: 10.1002/Dvdy.21704 |
0.676 |
|
2007 |
Shu X, Huang J, Dong Y, Choi J, Langenbacher A, Chen JN. Na,K-ATPase alpha2 and Ncx4a regulate zebrafish left-right patterning. Development (Cambridge, England). 134: 1921-30. PMID 17442698 DOI: 10.1242/Dev.02851 |
0.76 |
|
2007 |
Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y. A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes & Development. 21: 784-96. PMID 17374715 DOI: 10.1101/Gad.1499107 |
0.645 |
|
2007 |
Choi J, Dong L, Ahn J, Dao D, Hammerschmidt M, Chen JN. FoxH1 negatively modulates flk1 gene expression and vascular formation in zebrafish. Developmental Biology. 304: 735-44. PMID 17306248 DOI: 10.1016/J.Ydbio.2007.01.023 |
0.6 |
|
2007 |
Cibrián-Uhalte E, Langenbacher A, Shu X, Chen JN, Abdelilah-Seyfried S. Involvement of zebrafish Na+,K+ ATPase in myocardial cell junction maintenance. The Journal of Cell Biology. 176: 223-30. PMID 17227894 DOI: 10.1083/Jcb.200606116 |
0.718 |
|
2006 |
Mably JD, Chuang LP, Serluca FC, Mohideen MA, Chen JN, Fishman MC. santa and valentine pattern concentric growth of cardiac myocardium in the zebrafish. Development (Cambridge, England). 133: 3139-46. PMID 16873582 DOI: 10.1242/Dev.02469 |
0.549 |
|
2006 |
Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen J, Wang Y. A Novel Mitochondrial Matrix Serine/Threonine Protein Phosphatase Is Essential to Cardiomyocyte Survival and Cardiac Function by Regulating Mitochondrial Permeability Transition Journal of Cardiac Failure. 12: S42. DOI: 10.1016/J.Cardfail.2006.06.147 |
0.634 |
|
2005 |
Chen JN, Cowan DB, Mably JD. Cardiogenesis and the regulation of cardiac-specific gene expression. Heart Failure Clinics. 1: 157-70. PMID 17386843 DOI: 10.1016/J.Hfc.2005.03.002 |
0.377 |
|
2005 |
Langenbacher AD, Dong Y, Shu X, Choi J, Nicoll DA, Goldhaber JI, Philipson KD, Chen JN. Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 102: 17699-704. PMID 16314583 DOI: 10.1073/Pnas.0502679102 |
0.796 |
|
2005 |
Jin SW, Beis D, Mitchell T, Chen JN, Stainier DY. Cellular and molecular analyses of vascular tube and lumen formation in zebrafish. Development (Cambridge, England). 132: 5199-209. PMID 16251212 DOI: 10.1242/Dev.02087 |
0.492 |
|
2005 |
Beis D, Bartman T, Jin SW, Scott IC, D'Amico LA, Ober EA, Verkade H, Frantsve J, Field HA, Wehman A, Baier H, Tallafuss A, Bally-Cuif L, Chen JN, Stainier DY, et al. Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development (Cambridge, England). 132: 4193-204. PMID 16107477 DOI: 10.1242/Dev.01970 |
0.557 |
|
2005 |
Huang H, Zhang B, Hartenstein PA, Chen JN, Lin S. NXT2 is required for embryonic heart development in zebrafish. Bmc Developmental Biology. 5: 7. PMID 15790397 DOI: 10.1186/1471-213X-5-7 |
0.376 |
|
2003 |
Mably JD, Mohideen MA, Burns CG, Chen JN, Fishman MC. heart of glass regulates the concentric growth of the heart in zebrafish. Current Biology : Cb. 13: 2138-47. PMID 14680629 DOI: 10.1016/J.Cub.2003.11.055 |
0.535 |
|
2003 |
Shu X, Cheng K, Patel N, Chen F, Joseph E, Tsai HJ, Chen JN. Na,K-ATPase is essential for embryonic heart development in the zebrafish. Development (Cambridge, England). 130: 6165-73. PMID 14602677 DOI: 10.1242/dev.00844 |
0.316 |
|
2002 |
Childs S, Chen JN, Garrity DM, Fishman MC. Patterning of angiogenesis in the zebrafish embryo. Development (Cambridge, England). 129: 973-82. PMID 11861480 |
0.457 |
|
2001 |
Chen JN, van Bebber F, Goldstein AM, Serluca FC, Jackson D, Childs S, Serbedzija G, Warren KS, Mably JD, Lindahl P, Mayer A, Haffter P, Fishman MC. Genetic steps to organ laterality in zebrafish. Comparative and Functional Genomics. 2: 60-8. PMID 18628903 DOI: 10.1002/Cfg.74 |
0.473 |
|
2001 |
Peterson RT, Mably JD, Chen JN, Fishman MC. Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Current Biology : Cb. 11: 1481-91. PMID 11591315 DOI: 10.1016/S0960-9822(01)00482-1 |
0.549 |
|
2001 |
Chan J, Mably JD, Serluca FC, Chen JN, Goldstein NB, Thomas MC, Cleary JA, Brennan C, Fishman MC, Roberts TM. Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling. Developmental Biology. 234: 470-82. PMID 11397014 DOI: 10.1006/Dbio.2001.0281 |
0.439 |
|
2000 |
Chen JN, Fishman MC. Genetics of heart development. Trends in Genetics : Tig. 16: 383-8. PMID 10973066 DOI: 10.1016/S0168-9525(00)02075-8 |
0.535 |
|
2000 |
Chen JN, Fishman MC. Genetic dissection of heart development. Ernst Schering Research Foundation Workshop. 107-22. PMID 10943307 |
0.478 |
|
1998 |
Park M, Lewis C, Turbay D, Chung A, Chen JN, Evans S, Breitbart RE, Fishman MC, Izumo S, Bodmer R. Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes. Proceedings of the National Academy of Sciences of the United States of America. 95: 9366-71. PMID 9689086 DOI: 10.1073/Pnas.95.16.9366 |
0.545 |
|
1998 |
Serbedzija GN, Chen JN, Fishman MC. Regulation in the heart field of zebrafish. Development (Cambridge, England). 125: 1095-101. PMID 9463356 |
0.559 |
|
1997 |
Chen JN, van Eeden FJ, Warren KS, Chin A, Nüsslein-Volhard C, Haffter P, Fishman MC. Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development (Cambridge, England). 124: 4373-82. PMID 9334285 |
0.674 |
|
1996 |
Chen JN, Fishman MC. Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development (Cambridge, England). 122: 3809-16. PMID 9012502 |
0.572 |
|
1996 |
Chen JN, Haffter P, Odenthal J, Vogelsang E, Brand M, van Eeden FJ, Furutani-Seiki M, Granato M, Hammerschmidt M, Heisenberg CP, Jiang YJ, Kane DA, Kelsh RN, Mullins MC, Nüsslein-Volhard C. Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development (Cambridge, England). 123: 293-302. PMID 9007249 |
0.591 |
|
1996 |
Stainier DY, Fouquet B, Chen JN, Warren KS, Weinstein BM, Meiler SE, Mohideen MA, Neuhauss SC, Solnica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Driever W, Fishman MC. Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (Cambridge, England). 123: 285-92. PMID 9007248 DOI: 10.5167/Uzh-237 |
0.639 |
|
1991 |
Murphy M, Chen JN, George DL. Establishment and characterization of a human leptomeningeal cell line. Journal of Neuroscience Research. 30: 475-83. PMID 1724784 DOI: 10.1002/jnr.490300304 |
0.469 |
|
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