Johannes Backs

Heidelberg University, Tiffin, OH, United States 
Heart Failure, HDACs, CaMKII, Epigentics
"Johannes Backs"
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Saddouk FZ, Sun LY, Liu YF, et al. (2015) Ca2+/calmodulin-dependent protein kinase II-γ (CaMKIIγ) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Schäfer M, Oeing CU, Rohm M, et al. (2015) Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia Molecular Metabolism
Fredman G, Ozcan L, Spolitu S, et al. (2014) Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway. Proceedings of the National Academy of Sciences of the United States of America. 111: 14530-5
Lehmann LH, Rostosky JS, Buss SJ, et al. (2014) Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling. Proceedings of the National Academy of Sciences of the United States of America. 111: 13499-504
Weinreuter M, Kreusser MM, Beckendorf J, et al. (2014) CaM Kinase II mediates maladaptive post-infarct remodeling and pro-inflammatory chemoattractant signaling but not acute myocardial ischemia/reperfusion injury. Embo Molecular Medicine. 6: 1231-45
Kreusser MM, Lehmann LH, Riffel JH, et al. (2014) Aldosterone augments Na+-induced reduction of cardiac norepinephrine reuptake. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1169-77
Kreusser MM, Lehmann LH, Keranov S, et al. (2014) Cardiac CaM Kinase II genes δ and γ contribute to adverse remodeling but redundantly inhibit calcineurin-induced myocardial hypertrophy. Circulation. 130: 1262-73
Werfel S, Jungmann A, Lehmann L, et al. (2014) Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase. Cardiovascular Research. 104: 15-23
Dybkova N, Wagner S, Backs J, et al. (2014) Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa. Cardiovascular Research. 103: 168-77
Kreusser MM, Backs J. (2014) Integrated mechanisms of CaMKII-dependent ventricular remodeling. Frontiers in Pharmacology. 5: 36
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