Jeroen den Hertog

Leiden University, Leiden, Netherlands 
Molecular developmental zoology
"Jeroen den Hertog"
Cross-listing: Chemistry Tree


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Siegfried W. de Laat grad student 1992 Utrecht
 (Phosphotyrosine and neuronal differentiation of kinases and phosphatases)
Tony Hunter post-doc 1994 Salk Institute
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den Hertog J, de Laat SW. (2017) Hubrecht Institute Centennial - From embryos to stem cells. Developmental Biology. 428: 261-263
Stanford SM, Svensson MN, Sacchetti C, et al. (2015) "Receptor protein tyrosine phosphatase alpha enhances rheumatoid synovial fibroblast signaling and promotes arthritis in mice". Arthritis & Rheumatology (Hoboken, N.J.)
Vissers LE, Bonetti M, Paardekooper Overman J, et al. (2015) Heterozygous germline mutations in A2ML1 are associated with a disorder clinically related to Noonan syndrome. European Journal of Human Genetics : Ejhg. 23: 317-24
Paardekooper Overman J, Preisinger C, Prummel K, et al. (2014) Phosphoproteomics-mediated identification of Fer kinase as a target of mutant Shp2 in Noonan and LEOPARD syndrome. Plos One. 9: e106682
Pulido R, Baker SJ, Barata JT, et al. (2014) A unified nomenclature and amino acid numbering for human PTEN. Science Signaling. 7: pe15
Paardekooper Overman J, Yi JS, Bonetti M, et al. (2014) PZR coordinates Shp2 Noonan and LEOPARD syndrome signaling in zebrafish and mice. Molecular and Cellular Biology. 34: 2874-89
Leslie NR, den Hertog J. (2014) Mutant PTEN in Cancer: Worse Than Nothing. Cell. 157: 527-9
Bonetti M, Rodriguez-Martinez V, Overman JP, et al. (2014) Distinct and overlapping functions of ptpn11 genes in zebrafish development Plos One. 9
Bonetti M, Paardekooper Overman J, Tessadori F, et al. (2014) Noonan and LEOPARD syndrome Shp2 variants induce heart displacement defects in zebrafish. Development (Cambridge, England). 141: 1961-70
Finkelshtein E, Lotinun S, Levy-Apter E, et al. (2014) Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts. Molecular Biology of the Cell. 25: 1808-18
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