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Douglas A. Melton

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Development
Website:
http://www.hsci.harvard.edu/node/723
Google:
"Douglas Melton"
Bio:

http://www.scrb.harvard.edu/lab/50/home

Cross-listing: Neurotree - Chemistry Tree

Children

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Martha R.C. Bhattacharya research assistant 1996-2000 Harvard (Neurotree)
Lief E Fenno research assistant 2005-2007 Harvard (Neurotree)
Kyle Loh research assistant 2008-2008 Harvard (Neurotree)
Miguel R. Santos grad student 2002 Harvard (Neurotree)
Maya E. Kumar grad student 2003 Harvard (Neurotree)
Juliana R. Brown grad student 2005 Harvard (Neurotree)
William J. Anderson grad student 2000-2006
Kristen J. Brennand grad student 2002-2007 Harvard (Neurotree)
Richard I. Sherwood grad student 2009 Harvard (Neurotree)
Adriana Tajonar grad student 2012 Harvard (Neurotree)
Sinisa Hrvatin grad student 2013 Harvard (Neurotree)
Danny Ben-Zvi post-doc Harvard (Chemistry Tree)
Barak Blum post-doc Harvard
Chad Cowan post-doc (Cell Biology Tree)
Yuval Dor post-doc Harvard
Amy L. Greenwood post-doc Harvard (Neurotree)
Matthias Hebrok post-doc Harvard
Chris Kintner post-doc Harvard Medical School (Neurotree)
Paul A. Krieg post-doc Harvard Medical School (Cell Biology Tree)
Kimberly L. Mowry post-doc Harvard (Chemistry Tree)
XiaoXi Qiao post-doc Harvard (Neurotree)
Jayaraj Rajagopal post-doc Harvard Medical School (Microtree)
Clifford J. Tabin post-doc Harvard
Gerald H. Thomsen post-doc Harvard
Daniel L. Weeks post-doc Harvard (Neurotree)
Qiao Zhou post-doc Harvard (Neurotree)
Peng Yi post-doc 2008- Harvard
David Tannahill post-doc 1987-1989 Harvard (Chemistry Tree)
Peter Vize post-doc 1990-1992 Harvard
Ali Brivanlou post-doc 1991-1994 Harvard (Neurotree)
Danwei Huangfu post-doc 2005-2010 Harvard
Rene Maehr post-doc 2005-2011 Harvard College (Chemistry Tree)
Quinn P. Peterson post-doc 2011-2016 Harvard (Chemistry Tree)
Kevin C. Eggan research scientist 2003-2004 Harvard (Neurotree)
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Publications

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Magenheim J, Maestro MA, Sharon N, et al. (2023) Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors. Cell Stem Cell. 30: 488-497.e3
Leite NC, Pelayo GC, Melton DA. (2022) Genetic manipulation of stress pathways can protect stem-cell-derived islets from apoptosis in vitro. Stem Cell Reports. 17: 766-774
Gerace D, Kenty JH, Melton DA. (2021) 209.2: Engineering Immune-evasive Human Stem Cell-derived Islet Cells. Transplantation. 105: S13
Sintov E, Gerace D, Melton DA. (2021) A human ESC line for efficient CRISPR editing of pluripotent stem cells. Stem Cell Research. 57: 102591
Gerace D, Boulanger KR, Hyoje-Ryu Kenty J, et al. (2021) Generation of a heterozygous GAPDH-Luciferase human ESC line (HVRDe008-A-1) for in vivo monitoring of stem cells and their differentiated progeny. Stem Cell Research. 53: 102371
Cai EP, Ishikawa Y, Zhang W, et al. (2020) Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes. Nature Metabolism
Leite NC, Sintov E, Meissner TB, et al. (2020) Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells. Cell Reports. 32: 107894
Rasouli N, Melton DA, Alvarez-Dominguez JR. (2020) Purification of Live Stem-Cell-Derived Islet Lineage Intermediates. Current Protocols in Stem Cell Biology. 53: e111
Davis JC, Alves TC, Helman A, et al. (2020) Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis. Cell Reports. 31: 107623
Peterson QP, Veres A, Chen L, et al. (2020) A method for the generation of human stem cell-derived alpha cells. Nature Communications. 11: 2241
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