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Jeannie T. Lee

Affiliations: 
Molecular Biology Massachusetts General Hospital, Boston, MA 
Area:
X-Chromosome Inactivation
Website:
http://genetics.med.harvard.edu/faculty/lee
Google:
"Jeannie T. Lee"
Bio:

http://www.hms.harvard.edu/dms/bbs/fac/LeeJeannie.php
http://www.hhmi.org/research/investigators/lee.html
http://molbio.mgh.harvard.edu/leeweb/index.htm

Cross-listing: Chemistry Tree

Parents

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Robert Nussbaum grad student 1993 Penn
 (Construction and characterization of a human-specific Xpter-Xq27.3 yeast artificial chromosome library ; and Chromosome walking to the fragile X site)
Rudolf Jaenisch post-doc 1995 Whitehead Institute (MIT)
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Publications

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Sun S, Payer B, Namekawa S, et al. (2015) Xist imprinting is promoted by the hemizygous (unpaired) state in the male germ line. Proceedings of the National Academy of Sciences of the United States of America
Sunwoo H, Wu JY, Lee JT. (2015) The Xist RNA-PRC2 complex at 20-nm resolution reveals a low Xist stoichiometry and suggests a hit-and-run mechanism in mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 112: E4216-25
Minajigi A, Froberg JE, Wei C, et al. (2015) Chromosomes. A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation. Science (New York, N.Y.). 349
Pinter SF, Colognori D, Beliveau BJ, et al. (2015) Allelic Imbalance Is a Prevalent and Tissue-Specific Feature of the Mouse Transcriptome. Genetics. 200: 537-49
Davidovich C, Wang X, Cifuentes-Rojas C, et al. (2015) Toward a consensus on the binding specificity and promiscuity of PRC2 for RNA. Molecular Cell. 57: 552-8
Kung JT, Kesner B, An JY, et al. (2015) Locus-specific targeting to the X chromosome revealed by the RNA interactome of CTCF. Molecular Cell. 57: 361-75
Sarma K, Cifuentes-Rojas C, Ergun A, et al. (2015) ATRX directs binding of PRC2 to Xist RNA and polycomb targets Cell. 160: 568-569
Sarma K, Cifuentes-Rojas C, Ergun A, et al. (2014) ATRX directs binding of PRC2 to Xist RNA and Polycomb targets. Cell. 159: 869-83
Payer B, Lee JT. (2014) Coupling of X-chromosome reactivation with the pluripotent stem cell state. Rna Biology. 11: 798-807
Cifuentes-Rojas C, Hernandez AJ, Sarma K, et al. (2014) Regulatory interactions between RNA and polycomb repressive complex 2. Molecular Cell. 55: 171-85
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