Richard Klinghoffer
Affiliations: | 1998-2001 | Fred Hutchinson Cancer Research Center, Seattle, WA, United States | |
| 2010- | Presage Biosciences |
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"Richard Klinghoffer"
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| Morris SM, Mhyre AJ, Carmack SS, et al. (2018) A modified gene trap approach for improved high-throughput cancer drug discovery. Oncogene |
| Berndt JD, Frazier J, Grenley M, et al. (2012) Abstract 5116: Identification and rapidin vivovalidation of a novel drug combination for treating melanoma Cancer Research. 72: 5116-5116 |
| Andersen JN, Sathyanarayanan S, Di Bacco A, et al. (2010) Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors. Science Translational Medicine. 2: 43ra55 |
| Hamilton TG, Klinghoffer RA, Corrin PD, et al. (2003) Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms Molecular and Cellular Biology. 23: 4013-4025 |
| Cary LA, Klinghoffer RA, Sachsenmaier C, et al. (2002) Src catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading Molecular and Cellular Biology. 22: 2427-2440 |
| Klinghoffer RA, Hamilton TG, Hoch R, et al. (2002) An allelic series at the PDGFαR locus indicates unequal contributions of distinct signaling pathways during development Developmental Cell. 2: 103-113 |
| Klinghoffer RA, Mueting-Nelsen PF, Faerman A, et al. (2001) The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions Molecular Cell. 7: 343-354 |
| Tallquist MD, Klinghoffer RA, Heuchel R, et al. (2000) Retention of PDGFR-β function in mice in the absence of phosphatidylinositol 3′-kinase anti phospholipase Cγ signaling pathways Genes and Development. 14: 3179-3190 |
| Rosenkranz S, Ikuno Y, Leong FL, et al. (2000) Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression. The Journal of Biological Chemistry. 275: 9620-7 |
| Tallquist MD, Soriano P, Klinghoffer RA. (1999) Growth factor signaling pathways in vascular development Oncogene. 18: 7917-7932 |