Aaron A Hoskins

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
RNA, Splicing, Biochemistry, Biophysics, Single Molecule Fluorescence
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"Aaron Hoskins"

Parents

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Patricia J. LiWang research assistant 1997-1999 Purdue (Chemistry Tree)
Andy C. LiWang research assistant 1997-1999 Purdue (Chemistry Tree)
Christine A. Hrycyna research assistant 1999-2000 Purdue (Chemistry Tree)
JoAnne Stubbe grad student 2000-2006 MIT (Chemistry Tree)
Jeff Gelles post-doc 2006-2011 Brandeis U (Chemistry Tree)
Melissa J. Moore post-doc 2006-2011 UMass (Telomere and Telomerase Tree)

Children

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David Beier research assistant 2014-2018 UW Madison
Maggie Rodgers grad student 2011-2016 UW Madison
tucker Carrocci grad student 2011-2017 UW Madison
Joshua Larson grad student 2011-2017 UW Madison
Sarah Hansen grad student 2012-2019 UW Madison
Clarisse van der post-doc 2016-2020 UW Madison
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Publications

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Lipinski KA, Chi J, Chen X, et al. (2022) Yeast U6 snRNA made by RNA polymerase II is less stable but functional. Rna (New York, N.Y.)
Hansen SR, White DS, Scalf M, et al. (2022) Multi-step recognition of potential 5' splice sites by the U1 snRNP. Elife. 11
Kaur H, van der Feltz C, Sun Y, et al. (2022) Network theory reveals principles of spliceosome structure and dynamics. Structure (London, England : 1993). 30: 190-200.e2
Carrocci TJ, Hoskins AA. (2021) RNA processing: Fungal spliceosomes break the mold. Current Biology : Cb. 31: R1482-R1484
Love SL, Hoskins AA. (2021) Stuck on UUUU: New splicing inhibitors enhance U2AF2-RNA binding. Cell Chemical Biology. 28: 1106-1108
van der Feltz C, Nikolai B, Schneider C, et al. (2021) Saccharomyces cerevisiae Ecm2 Modulates the Catalytic Steps of pre-mRNA Splicing. Rna (New York, N.Y.)
van der Feltz C, Hoskins AA. (2019) Structural and functional modularity of the U2 snRNP in pre-mRNA splicing. Critical Reviews in Biochemistry and Molecular Biology. 54: 443-465
Beier DH, Carrocci TJ, van der Feltz C, et al. (2019) Dynamics of the DEAD-box ATPase Prp5 RecA-like domains provide a conformational switch during spliceosome assembly. Nucleic Acids Research. 47: 10842-10851
Hansen SR, Nikolai BJ, Spreacker PJ, et al. (2019) Chemical Inhibition of Pre-mRNA Splicing in Living Saccharomyces cerevisiae. Cell Chemical Biology. 26: 443-448.e3
Carrocci TJ, Paulson JC, Hoskins AA. (2018) Functional analysis of Hsh155/SF3b1 interactions with the U2 snRNA/branch site duplex. Rna (New York, N.Y.). 24: 1028-1040
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