Thomas Claydon, PhD

Affiliations: 
Biomedical Physiology and Kinesiology Simon Fraser University, Burnaby, British Columbia, Canada 
Website:
http://www.sfu.ca/mcpg/Claydon.html
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"Thomas Claydon"
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Publications

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Simpson KE, Faizi S, Venkateshappa R, et al. (2022) CRISPR-Cas9-mediated Precise Knock-in Edits in Zebrafish Hearts. Journal of Visualized Experiments : Jove
Whittaker DG, Wang J, Shuttleworth JG, et al. (2022) Ion channel model reduction using manifold boundaries. Journal of the Royal Society, Interface. 19: 20220193
Kemp JM, Whittaker DG, Venkateshappa R, et al. (2021) Electrophysiological characterization of the hERG R56Q LQTS variant and targeted rescue by the activator RPR260243. The Journal of General Physiology. 153
Shi YP, Pang Z, Venkateshappa R, et al. (2020) The hERG channel activator, RPR260243, enhances protective I current in early refractory reducing arrhythmogenicity in zebrafish hearts. American Journal of Physiology. Heart and Circulatory Physiology
Shi YP, Thouta S, Claydon TW. (2020) Modulation of hERG K Channel Deactivation by Voltage Sensor Relaxation. Frontiers in Pharmacology. 11: 139
Sergeev V, Perry F, Roston TM, et al. (2017) Functional characterization of a novel hERG variant in a family with recurrent sudden infant death syndrome: Retracting a genetic diagnosis. Forensic Science International. 284: 39-45
Lehman A, Thouta S, Mancini GMS, et al. (2017) Loss-of-Function and Gain-of-Function Mutations in KCNQ5 Cause Intellectual Disability or Epileptic Encephalopathy. American Journal of Human Genetics
Thouta S, Hull CM, Shi YP, et al. (2017) Stabilization of the Activated hERG Channel Voltage Sensor by Depolarization Involves the S4-S5 Linker. Biophysical Journal. 112: 300-312
Genge CE, Lin E, Lee L, et al. (2016) The Zebrafish Heart as a Model of Mammalian Cardiac Function. Reviews of Physiology, Biochemistry and Pharmacology
Zandberg WF, Bakhtiari AB, Erno Z, et al. (2012) Photothermal release of small molecules from gold nanoparticles in live cells. Nanomedicine : Nanotechnology, Biology, and Medicine. 8: 908-15
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