Yen May CHENG

Affiliations: 
Biomedical Physiology and Kinesiology Simon Fraser University, Burnaby, British Columbia, Canada 
 2018- STEMCELL technologies 
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"Yen CHENG"
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Simpson KE, Faizi S, Venkateshappa R, et al. (2022) CRISPR-Cas9-mediated Precise Knock-in Edits in Zebrafish Hearts. Journal of Visualized Experiments : Jove
Shi YP, Thouta S, Cheng YM, et al. (2018) Extracellular protons accelerate hERG channel deactivation by destabilizing voltage sensor relaxation. The Journal of General Physiology
Thouta S, Hull CM, Shi YP, et al. (2017) Stabilization of the Activated hERG Channel Voltage Sensor by Depolarization Involves the S4-S5 Linker. Biophysical Journal. 112: 300-312
Guo J, Cheng YM, Lees-Miller JP, et al. (2015) NS1643 interacts around L529 of hERG to alter voltage sensor movement on the path to activation. Biophysical Journal. 108: 1400-13
Thouta S, Sokolov S, Abe Y, et al. (2014) Proline scan of the HERG channel S6 helix reveals the location of the intracellular pore gate. Biophysical Journal. 106: 1057-69
Shi YP, Cheng YM, Van Slyke AC, et al. (2014) External protons destabilize the activated voltage sensor in hERG channels. European Biophysics Journal : Ebj. 43: 59-69
Cheng YM, Hull CM, Niven CM, et al. (2013) Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels. The Journal of General Physiology. 142: 289-303
Cheng YM, Claydon TW. (2012) Voltage-dependent gating of HERG potassium channels. Frontiers in Pharmacology. 3: 83
Van Slyke AC, Cheng YM, Mafi P, et al. (2012) Proton block of the pore underlies the inhibition of hERG cardiac K+ channels during acidosis. American Journal of Physiology. Cell Physiology. 302: C1797-806
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