Lauri Saxen - Publications

Affiliations: 
University of Helsinki, Helsingfors, Finland 

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
1996 RAPOLA J, SAXEN L, VAINIO T. VIRAL SUSCEPTIBILITY AND EMBRYONIC DIFFERENTIATION. 6. CYTOCHEMICAL STUDIES ON NORMAL AND POLYOMA INFECTED FOETAL KIDNEY IN VITRO. Acta Pathologica Et Microbiologica Scandinavica. 63: 249-60. PMID 14295444 DOI: 10.1111/Apm.1965.63.2.249  0.311
1995 Ritvos O, Tuuri T, Erämaa M, Sainio K, Hildén K, Saxén L, Gilbert SF. Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse. Mechanisms of Development. 50: 229-45. PMID 7619733 DOI: 10.1016/0925-4773(94)00342-K  0.32
1993 Hormia M, Thesleff I, Perheentupa J, Pesonen K, Saxén L. Increased rate of salivary epidermal growth factor secretion in patients with juvenile periodontitis. Scandinavian Journal of Dental Research. 101: 138-44. PMID 8322007 DOI: 10.1111/J.1600-0722.1993.Tb01653.X  0.417
1992 Vainio S, Jalkanen M, Bernfield M, Saxén L. Transient expression of syndecan in mesenchymal cell aggregates of the embryonic kidney. Developmental Biology. 152: 221-32. PMID 1644217 DOI: 10.1016/0012-1606(92)90130-9  0.333
1992 Saxén L, Thesleff I. Epithelial-mesenchymal interactions in murine organogenesis. Ciba Foundation Symposium. 165: 183-93; discussion 1. PMID 1516468  0.489
1991 Nordlund L, Hormia M, Saxén L, Thesleff I. Immunohistochemical localization of epidermal growth factor receptors in human gingival epithelia. Journal of Periodontal Research. 26: 333-8. PMID 1831500 DOI: 10.1111/J.1600-0765.1991.Tb02071.X  0.459
1989 Vainio S, Lehtonen E, Jalkanen M, Bernfield M, Saxén L. Epithelial-mesenchymal interactions regulate the stage-specific expression of a cell surface proteoglycan, syndecan, in the developing kidney. Developmental Biology. 134: 382-91. PMID 2663574 DOI: 10.1016/0012-1606(89)90110-3  0.339
1988 Thesleff I, Viinikka L, Saxén L, Lehtonen E, Perheentupa J. The parotid gland is the main source of human salivary epidermal growth factor. Life Sciences. 43: 13-8. PMID 3290608 DOI: 10.1016/0024-3205(88)90231-7  0.428
1987 Saxén L, Lehtonen E. Embryonic kidney in organ culture. Differentiation; Research in Biological Diversity. 36: 2-11. PMID 3328727 DOI: 10.1111/J.1432-0436.1987.Tb00176.X  0.331
1987 Saxén L, Sariola H. Early organogenesis of the kidney. Pediatric Nephrology (Berlin, Germany). 1: 385-92. PMID 3153305 DOI: 10.1007/Bf00849241  0.302
1986 Saxén L, Sariola H, Lehtonen E. Sequential cell and tissue interactions governing organogenesis of the kidney. Anatomy and Embryology. 175: 1-6. PMID 3799983 DOI: 10.1007/Bf00315450  0.32
1986 Lehtonen E, Saxén L. Control of differentiation Duodecim LääKetieteellinen Aikakauskirja. 101: 27-51. DOI: 10.1007/978-1-4613-2101-9_2  0.327
1985 Saxén L, Lehtonen E, Thesleff I. [Control of differentiation]. Duodecim; LääKetieteellinen Aikakauskirja. 101: 310-22. PMID 3979321  0.432
1985 Lehtonen E, Virtanen I, Saxén L. Reorganization of intermediate filament cytoskeleton in induced metanephric mesenchyme cells is independent of tubule morphogenesis. Developmental Biology. 108: 481-90. PMID 2416612 DOI: 10.1016/0012-1606(85)90051-X  0.331
1983 Saxén L, Salonen J, Ekblom P, Nordling S. DNA synthesis and cell generation cycle during determination and differentiation of the metanephric mesenchyme. Developmental Biology. 98: 130-8. PMID 6862101 DOI: 10.1016/0012-1606(83)90341-X  0.319
1983 Ekblom P, Thesleff I, Saxén L, Miettinen A, Timpl R. Transferrin as a fetal growth factor: acquisition of responsiveness related to embryonic induction. Proceedings of the National Academy of Sciences of the United States of America. 80: 2651-5. PMID 6405384 DOI: 10.1073/Pnas.80.9.2651  0.557
1983 Sariola H, Ekblom P, Lehtonen E, Saxén L. Differentiation and vascularization of the metanephric kidney grafted on the chorioallantoic membrane. Developmental Biology. 96: 427-35. PMID 6339300 DOI: 10.1016/0012-1606(83)90180-X  0.321
1981 Ekblom P, Thesleff I, Miettinen A, Saxén L. Organogenesis in a defined medium supplemented with transferrin. Cell Differentiation. 10: 281-8. PMID 7307079 DOI: 10.1016/0045-6039(81)90010-5  0.54
1981 Saxén L. Neural induction: past, present, and future. Current Topics in Developmental Biology. 409-18. PMID 7004787 DOI: 10.1016/S0070-2153(08)60125-8  0.313
1980 Leivo I, Ekblom P, Thesleff I, Wartiovaara J, Saxén L. [Connective tissue and its differentiation]. Duodecim; LääKetieteellinen Aikakauskirja. 96: 1550-61. PMID 7238369  0.45
1980 Ekblom P, Miettinen A, Saxen L. Induction of brush border antigens of the proximal tubule in the developing kidney Developmental Biology. 74: 263-274. PMID 6989689 DOI: 10.1016/0012-1606(80)90429-7  0.318
1980 Ekblom P, Alitalo K, Vaheri A, Timpl R, Saxén L. Induction of a basement membrane glycoprotein in embryonic kidney: possible role of laminin in morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 77: 485-9. PMID 6987652 DOI: 10.1073/Pnas.77.1.485  0.325
1980 Hurmerinta K, Thesleff I, Saxén L. In vitro inhibition of mouse odontoblast differentiation by vitamin A. Archives of Oral Biology. 25: 385-93. PMID 6934733 DOI: 10.1016/0003-9969(80)90004-7  0.479
1979 Hurmerinta K, Thesleff I, Saxén L. Inhibition of tooth germ differentiation in vitro by diazo-oxo-norleucine (DON). Journal of Embryology and Experimental Morphology. 50: 99-109. PMID 458364  0.495
1979 Ekblom P, Lash JW, Lehtonen E, Nordling S, Saxén L. Inhibition of morphogenetic cell interactions by 6-diazo-5-oxo-norleucine (DON). Experimental Cell Research. 121: 121-6. PMID 446523 DOI: 10.1016/0014-4827(79)90451-8  0.304
1978 Palva T, Thesleff I, Saxén L. Organ culture studies on human skin and cholesteatoma epithelium. Contact with connective tissue and exposure to vitamin A. Acta Oto-Laryngologica. 85: 307-12. PMID 665201  0.443
1978 Thesleff I, Lehtonen E, Saxén L. Basement membrane formation in transfilter tooth culture and its relation to odontoblast differentiation. Differentiation; Research in Biological Diversity. 10: 71-9. PMID 640305 DOI: 10.1111/J.1432-0436.1978.Tb00948.X  0.513
1977 Thesleff I, Lehtonen E, Wartiovaara J, Saxén L. Interference of tooth differentiation with interposed filters. Developmental Biology. 58: 197-203. PMID 873058 DOI: 10.1016/0012-1606(77)90085-9  0.489
1976 Saxen L, Lehtonen E, Karkinen Jaaskelainen M, Karkinen-Jääskeläinen M, Nordling S, Wartiovaara J. Are morphogenetic tissue interactions mediated by transmissible signal substances or through cell contacts? Nature. 259: 662-663. PMID 1250416 DOI: 10.1038/259662A0  0.316
1976 Toivonen S, Tarin D, Saxén L. The transmission of morphogenetic signals from amphibian mesoderm to ectoderm in primary induction. Differentiation; Research in Biological Diversity. 5: 49-55. PMID 789165 DOI: 10.1111/J.1432-0436.1976.Tb00891.X  0.543
1975 Toivonen S, Tarin D, Saxén L, Tarin PJ, Wartiovaara J. Transfilter studies on neural induction in the newt. Differentiation; Research in Biological Diversity. 4: 1-7. PMID 1205028 DOI: 10.1111/J.1432-0436.1975.Tb01435.X  0.564
1974 Virtanen I, Saxén L. Ultrastructural characteristics of mumps virus replication in the cataracts of chick embryonic lens. Experimental Eye Research. 17: 463-72. PMID 4783184 DOI: 10.1016/0014-4835(73)90227-3  0.306
1971 Saxén L. Failure to demonstrate tubule induction in a heterologous mesenchyme. Developmental Biology. 23: 511-23. PMID 5500583 DOI: 10.1016/0012-1606(70)90137-5  0.301
1971 Saxén L, Saksela E. Transmission and spread of embryonic induction. II. Exclusion of an assimilatory transmission mechanism in kidney tubule induction. Experimental Cell Research. 66: 369-77. PMID 5104874 DOI: 10.1016/0014-4827(71)90690-2  0.334
1970 Saxén L. Defective Regulatory Mechanisms in Teratogenesis International Journal of Gynecology & Obstetrics. 8: 80-86. DOI: 10.1007/978-94-011-6621-8_8  0.303
1968 Lahti A, Saxen L. Effect of hydrocortisone on the closure of palatal shelves in vivo and in vitro. Nature. 216: 1217-8. PMID 6076070 DOI: 10.1038/2161217A0  0.303
1968 Toivonen S, Saxen L. Morphogenetic interaction of presumptive neural and mesodermal cells mixed in different ratios. Science (New York, N.Y.). 159: 539-40. PMID 5635157 DOI: 10.1126/Science.159.3814.539  0.582
1966 Saxen L, Wartiovaara J. Cell contact and cell adhesion during tissue organization. International Journal of Cancer. 1: 271-90. PMID 5944066 DOI: 10.1002/Ijc.2910010307  0.328
1966 Vainio T, Jainchill J, Clement K, Saxén L. Studies on kidney tubulogenesis. VI. Survival and nucleic acid metabolism of differentiating mouse metanephrogenic mesenchyme in vitro. Journal of Cellular Physiology. 66: 311-7. PMID 5884358 DOI: 10.1002/Jcp.1030660308  0.325
1966 Toivonen S, Saxén L. Late tissue interactions in the segregation of the central nervous system. Annales Medicinae Experimentalis Et Biologiae Fenniae. 44: 128-30. PMID 4961007  0.51
1965 SAXEN L, TOIVONEN S, VAINIO T, KORHONEN P. [STUDIES ON TUBULOGENESIS OF THE KIDNEYS. 3. ANALYSIS OF THE EARLY DEVELOPMENT WITH THE TIME LAPSE METHOD]. Zeitschrift FüR Naturforschung. Teil B: Chemie, Biochemie, Biophysik, Biologie. 20: 340-3. PMID 14308007 DOI: 10.1515/Znb-1965-0415  0.549
1964 SAXEN L, TOIVONEN S, VAINIO T. INITIAL STIMULUS AND SUBSEQUENT INTERACTIONS IN EMBRYONIC INDUCTION. Journal of Embryology and Experimental Morphology. 12: 333-8. PMID 14192054  0.504
1964 SORIANO L, SAXEN L, VAINIO T, TOIVONEN S. THE DEVELOPMENT OF OESOPHAGEAL AND TRACHEOBRONCHIAL EPITHELIA IN VITRO. Acta Anatomica. 57: 105-14. PMID 14187975 DOI: 10.1159/000142541  0.571
1964 Toivonen S, Vainio T, Saxén L. The Effect of Actinomycin D on Primary Embryonic Induction Revue Suisse De Zoologie.. 71: 139-146. DOI: 10.5962/Bhl.Part.75601  0.543
1964 Soriano L, Saxén L, Vainio T, Toivonen S. The development of oesophageal and tracheobronchial eithelial in vitro Cells Tissues Organs. 57: 105-114. DOI: 10.1159/000142541  0.524
1963 Toivonen S, Saxén L, Vainio T. Wilhelm Roux' Archiv Fur Entwicklungsmechanik Der Organismen. 154: 293-307. PMID 28355026 DOI: 10.1007/BF00582079  0.517
1963 VAINIO T, SAXEN L, TOIVONEN S. VIRAL SUSCEPTIBILITY AND EMBRYONIC DIFFERENTIATION. III. CORRELATION BETWEEN AN INDUCTIVE TISSUE INTERACTION AND THE ONSET OF VIRAL RESISTANCE. Journal of the National Cancer Institute. 31: 1533-47. PMID 14087667 DOI: 10.1093/Jnci/31.6.1533  0.575
1963 VAINIO T, SAXEN L, TOIVONEN S. Viral susceptibility and embryonic differentiation. 2. Immunofluorescence studies of viral infection in the developing mouse kidney in vitro. Acta Pathologica Et Microbiologica Scandinavica. 58: 205-11. PMID 13995766 DOI: 10.1111/J.1699-0463.1963.Tb01562.X  0.582
1963 VAINIO T, SAXEN L, TOIVONEN S, RAPOLA J. Polyoma virus and mouse kidney organogenesis in vitro. Acta - Unio Internationalis Contra Cancrum. 19: 306-8. PMID 13995764  0.521
1963 Vainio T, Saxén L, Toivonen S. The acquisition of cellular resistance to polyoma virus during embryonic differentiation Virology. 20: 380-385. PMID 13995763 DOI: 10.1016/0042-6822(63)90131-4  0.563
1963 SAXEN L, VAINIO T, TOIVONEN S. Viral susceptibility and embryonic differentiation. 1. The histopathology of mouse kidney rudiments infected with polyoma and vesicular stomatitis viruses in vitro. Acta Pathologica Et Microbiologica Scandinavica. 58: 191-204. PMID 13986967 DOI: 10.1111/J.1699-0463.1963.Tb01561.X  0.578
1963 Toivonen S, Saxén L, Vainio T. über die Natur der deuterenkephalen Leistung in der embryonalen Induktion Wilhelm Roux' Archiv FüR Entwicklungsmechanik Der Organismen. 154: 293-307. DOI: 10.1007/BF00582079  0.477
1962 SAXEN L, VAINIO T, TOIVONEN S. Effect of polyoma virus on mouse kidney rudiment in vitro. Journal of the National Cancer Institute. 29: 597-631. PMID 14497698 DOI: 10.1093/Jnci/29.3.597  0.565
1962 VAINIO T, SAXEN L, TOIVONEN S, RAPOLA J. The transmission problem in primary embryonic induction. Experimental Cell Research. 27: 527-38. PMID 13995765 DOI: 10.1016/0014-4827(62)90015-0  0.558
1962 NYHOLM M, SAXEN L, TOIVONEN S, VAINIO T. Electron microscopy of transfilter neural induction. Experimental Cell Research. 28: 209-12. PMID 13939304 DOI: 10.1016/0014-4827(62)90330-0  0.53
1961 SAXEN L, TOIVONEN S. The two-gradient hypothesis in primary induction. The combined effect of two types of inductors mixed in different ratios. Journal of Embryology and Experimental Morphology. 9: 514-33. PMID 14497697  0.494
1961 TOIVONEN S, SAXEN L, VAINIO T. Quantitative evidence for the two-gradient hypothesis in the primary induction. Experientia. 17: 86-7. PMID 13777212 DOI: 10.1007/Bf02171440  0.529
1961 SAXEN L, TOIVONEN S, VAINIO T. The embryonic inductive action of cells cultivated in vitro. Acta Pathologica Et Microbiologica Scandinavica. Supplement. 51: 163-4. PMID 13746973  0.553
1961 TOIVONEN S, KOHONEN J, SAUKKONEN J, SAXÉN L, VAINIO T. PRELIMINARY OBSERVATIONS OF THE INHIBITION OF NEURAL INDUCTION BY 5-FLUOROURACIL* Embryologia. 6: 177-184. DOI: 10.1111/J.1440-169X.1961.Tb00123.X  0.547
1960 VAINIO T, SAXEN L, TOIVONEN S. Transfer of the antigenicity of guinea pig bone marrow implants to the graft tissue in explantation experiments. Experientia. 16: 27-9. PMID 13840706 DOI: 10.1007/Bf02201785  0.536
1960 SAXEN L, TOIVONEN S. [The endocrine control of metamorphosis]. El Día MéDico. 32: 1856-64. PMID 13746974  0.473
1958 SAXEN L, TOIVONEN S. The dependence of the embryonic inductive action of HeLa cells on their growth media. Journal of Embryology and Experimental Morphology. 6: 616-33. PMID 13611140  0.527
1958 VAINIO T, TOIVONEN S, SAXEN L. Embryonic inductive capacity of the blood and its constituents. Annales Medicinae Experimentalis Et Biologiae Fenniae. 36: 285-91. PMID 13595343  0.486
1958 PENTTINEN K, SAXEN E, SAXEN L, TOIVONEN S, VAINIO T. Importance of the growth medium on the morphological behaviour, inductive action and immunology of cells. Annales Medicinae Experimentalis Et Biologiae Fenniae. 36: 27-46. PMID 13595308  0.524
1957 TOIVONEN S, SAXEN L. Embryonic inductive action of normal and leukemic bone marrow of the rat. II. Journal of the National Cancer Institute. 19: 1095-105. PMID 13502764 DOI: 10.1093/jnci/19.6.1095  0.501
1957 SAXEN L, SAXEN E, TOIVONEN S, SALIMAKI K. Quantitative investigation on the anterior pituitary-thyroid mechanism during frog metamorphosis. Endocrinology. 61: 35-44. PMID 13437952 DOI: 10.1210/Endo-61-1-35  0.548
1957 SAXÉN L, TOIVONEN S. THE EMBRYONIC INDUCTIVE ACTION OF NORMAL AND REGENERATING RAT LIVER Embryologia. 3: 353-360. DOI: 10.1111/J.1440-169X.1957.Tb00081.X  0.546
1956 SAXEN L, TOIVONEN S. Inductive action of normal and leucemic bone-marrow of the rat; experiments with amphibian embryos. Annales Medicinae Experimentalis Et Biologiae Fenniae. 34: 235-41. PMID 13381996  0.513
1956 SAXEN E, SAXEN L, TOIVONEN S. Cytology of the anterior pituitary and thyroid function; a study of delayed metamorphosis and neoteny. Annales Medicinae Experimentalis Et Biologiae Fenniae. 34: 34-47. PMID 13373087  0.49
1956 SAXEN E, SAXEN L, TOIVONEN S. Determination of thyroid activity by quantitative microdensitometry using I131. Annales Medicinae Experimentalis Et Biologiae Fenniae. 34: 7-14. PMID 13373084  0.483
1955 TOIVONEN S, SAXEN L. The simultaneous inducing action of liver and bone-marrow of the guinea-pig in implantation and explantation experiments with embryos of Triturus. Experimental Cell Research. 346-57. PMID 13344491  0.508
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