Kirk M. Habegger, Ph.D. - Publications

Affiliations: 
2009 Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Physiology Biology, Cell Biology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Covert JD, Grice BA, Thornburg MG, Kaur M, Ryan AP, Tackett L, Bhamidipati T, Stull ND, Kim T, Habegger KM, McClain DA, Brozinick JT, Elmendorf JS. An early, reversible cholesterolgenic etiology of diet-induced insulin resistance. Molecular Metabolism. 72: 101715. PMID 37019209 DOI: 10.1016/j.molmet.2023.101715  0.766
2022 Kim T, Nason S, Antipenko J, Finan B, Shalev A, DiMarchi R, Habegger KM. Hepatic TORC2 Signaling Facilitates Acute Glucagon-Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice. Diabetes. PMID 35877180 DOI: 10.2337/db21-1018  0.437
2022 Habegger K. Crosstalk Between Insulin- and Glucagon-Receptor Signaling in the Hepatocyte. Diabetes. PMID 35657690 DOI: 10.2337/dbi22-0002  0.422
2021 Sammy MJ, Connelly AW, Brown JA, Holleman C, Habegger KM, Ballinger SW. Mito-Mendelian Interactions Alter in vivo Glucose Metabolism and Insulin Sensitivity in Healthy Mice. American Journal of Physiology. Endocrinology and Metabolism. PMID 34370595 DOI: 10.1152/ajpendo.00069.2021  0.469
2021 Zeigerer A, Sekar R, Kleinert M, Nason S, Habegger KM, Müller TD. Glucagon's Metabolic Action in Health and Disease. Comprehensive Physiology. 11: 1759-1783. PMID 33792899 DOI: 10.1002/cphy.c200013  0.348
2020 Brahma MK, Ha CM, Pepin ME, Mia S, Sun Z, Chatham JC, Habegger KM, Abel ED, Paterson AJ, Young ME, Wende AR. Increased Glucose Availability Attenuates Myocardial Ketone Body Utilization. Journal of the American Heart Association. 9: e013039. PMID 32750298 DOI: 10.1161/Jaha.119.013039  0.396
2020 Ren G, Kim T, Kim HS, Young ME, Muccio DD, Atigadda VR, Blum SI, Tse HM, Habegger KM, Bhatnagar S, Coric T, Bjornsti MA, Shalev A, Frank SJ, Kim JA. A Small Molecule, UAB126, Reverses Diet-Induced Obesity and its Associated Metabolic Disorders. Diabetes. PMID 32611548 DOI: 10.2337/Db19-1001  0.339
2020 Müller TD, Habegger K. Revisiting the Pharmacological Value of Glucagon: An Editorial for the Special Issue "The Biology and Pharmacology of Glucagon". International Journal of Molecular Sciences. 21. PMID 31936192 DOI: 10.3390/Ijms21020383  0.451
2020 Kim T, Nason SR, Antipenko J, Presedo N, Finan B, DiMarchi RD, Habegger KM. SAT-655 Bile Acid Sequestration Synergistically Accelerates Glucagon Receptor-Stimulated Body Weight Loss in Diet-Induced Obese Mice Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1106  0.404
2019 Nason SR, Kim T, Antipenko JP, Finan B, DiMarchi R, Hunter CS, Habegger KM. Glucagon-Receptor Signaling Reverses Hepatic Steatosis Independent of Leptin Receptor Expression. Endocrinology. PMID 31673703 DOI: 10.1210/Endocr/Bqz013  0.331
2019 Kleinert M, Sachs S, Habegger KM, Hofmann SM, Müller TD. Glucagon Regulation of Energy Expenditure. International Journal of Molecular Sciences. 20. PMID 31671603 DOI: 10.3390/Ijms20215407  0.301
2019 Bethea M, Liu Y, Wade AK, Mullen R, Gupta R, Gelfanov V, DiMarchi R, Bhatnagar S, Behringer R, Habegger KM, Hunter CS. The islet-expressed Lhx1 transcription factor interacts with Islet-1 and contributes to glucose homeostasis. American Journal of Physiology. Endocrinology and Metabolism. PMID 30620636 DOI: 10.1152/Ajpendo.00235.2018  0.392
2019 KIM T, ANTIPENKO JP, NASON S, PRESEDO N, VAN DER POL WJ, FINAN B, DIMARCHI R, MORROW CD, HABEGGER KM. 1965-P: Glucagon Receptor Agonism Stimulates Body Weight Loss in Antibiotic Treatment in Obese Mice Diabetes. 68: 1965-P. DOI: 10.2337/Db19-1965-P  0.371
2019 Nason S, Kim T, Antipenko JP, Finan B, Dimarchi R, Habegger KM. 1870-P: Glucagon-Receptor Signaling Reverses Hepatic Steatosis Independent of Leptin Receptor Expression Diabetes. 68. DOI: 10.2337/Db19-1870-P  0.334
2018 Rivero-Gutierrez B, Haller A, Holland J, Yates E, Khrisna R, Habegger K, Dimarchi R, D'Alessio D, Perez-Tilve D. Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia. Molecular Metabolism. PMID 30170980 DOI: 10.1016/J.Molmet.2018.07.012  0.323
2018 Kim T, Holleman CL, Nason S, Arble DM, Ottaway N, Chabenne J, Loyd C, Kim JA, Sandoval D, Drucker DJ, DiMarchi R, Perez-Tilve D, Habegger KM. Hepatic Glucagon-Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents. Diabetes. PMID 30150304 DOI: 10.2337/Db18-0068  0.577
2018 Kim T, Nason S, Holleman C, Pepin M, Wilson L, Berryhill TF, Wende AR, Steele C, Young ME, Barnes S, Drucker DJ, Finan B, DiMarchi R, Perez-Tilve D, Tschoep M, ... Habegger KM, et al. Glucagon-receptor Signaling Regulates Energy Metabolism Via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21. Diabetes. PMID 29925501 DOI: 10.2337/Db17-1502  0.347
2018 Pepin ME, Padgett LE, McDowell RE, Burg AR, Brahma MK, Holleman C, Kim T, Crossman D, Kutsch O, Tse HM, Wende AR, Habegger KM. Antiretroviral therapy potentiates high-fat diet induced obesity and glucose intolerance. Molecular Metabolism. PMID 29731256 DOI: 10.1016/J.Molmet.2018.04.006  0.308
2018 KANG M, ANTIPENKO JP, LIU X, HABEGGER KM, TIMOTHY GARVEY W. Maternal Dietary Manipulation Programs Offspring’s Metabolism Diabetes. 67: 281-LB. DOI: 10.2337/Db18-281-Lb  0.376
2017 Ryan KK, Packard AEB, Larson KR, Stout J, Fourman SM, Thompson AMK, Ludwick K, Habegger KM, Stemmer K, Itoh N, Perez-Tilve D, Tschöp MH, Seeley RJ, Ulrich-Lai YM. Dietary manipulations that induce ketosis activate the HPA axis in male rats and mice: a potential role for fibroblast growth factor-21. Endocrinology. PMID 29077838 DOI: 10.1210/En.2017-00486  0.303
2016 Loyd C, Liu Y, Kim T, Holleman C, Galloway J, Bethea M, Ediger BN, Tang Y, Swain TA, Stoffers DA, Rowe GC, Young M, Steele C, Habegger KM, Hunter CS. Ldb1 Regulates Energy Homeostasis During Diet-Induced Obesity. Endocrinology. en20161791. PMID 28009534 DOI: 10.1210/En.2016-1791  0.487
2016 Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Müller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sánchez-Garrido MA, Liu P, Tuckermann J, ... ... Habegger KM, et al. Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease. Cell. PMID 27720451 DOI: 10.1016/J.Cell.2016.09.014  0.345
2015 Stemmer K, Zani F, Habegger KM, Neff C, Kotzbeck P, Bauer M, Yalamanchilli S, Azad A, Lehti M, Martins PJ, Müller TD, Pfluger PT, Seeley RJ. FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice. Diabetologia. PMID 26099854 DOI: 10.1007/S00125-015-3668-7  0.327
2015 Finan B, Yang B, Ottaway N, Smiley DL, Ma T, Clemmensen C, Chabenne J, Zhang L, Habegger KM, Fischer K, Campbell JE, Sandoval D, Seeley RJ, Bleicher K, Uhles S, et al. A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents. Nature Medicine. 21: 27-36. PMID 25485909 DOI: 10.1038/Nm.3761  0.359
2014 Hoffman NJ, Penque BA, Habegger KM, Sealls W, Tackett L, Elmendorf JS. Chromium enhances insulin responsiveness via AMPK. The Journal of Nutritional Biochemistry. 25: 565-72. PMID 24725432 DOI: 10.1016/J.Jnutbio.2014.01.007  0.771
2014 Habegger KM, Heppner KM, Amburgy SE, Ottaway N, Holland J, Raver C, Bartley E, Müller TD, Pfluger PT, Berger J, Toure M, Benoit SC, Dimarchi RD, Perez-Tilve D, D'Alessio DA, et al. GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats. Diabetes. 63: 505-13. PMID 24186863 DOI: 10.2337/Db13-0511  0.418
2014 Habegger KM, Al-Massadi O, Heppner KM, Myronovych A, Holland J, Berger J, Yi CX, Gao Y, Lehti M, Ottaway N, Amburgy S, Raver C, Müller TD, Pfluger PT, Kohli R, et al. Duodenal nutrient exclusion improves metabolic syndrome and stimulates villus hyperplasia. Gut. 63: 1238-46. PMID 24107591 DOI: 10.1136/Gutjnl-2013-304583  0.387
2014 Heppner KM, Piechowski CL, Müller A, Ottaway N, Sisley S, Smiley DL, Habegger KM, Pfluger PT, Dimarchi R, Biebermann H, Tschöp MH, Sandoval DA, Perez-Tilve D. Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors. Diabetes. 63: 122-31. PMID 24062249 DOI: 10.2337/Db13-0414  0.487
2014 Heppner KM, Piechowski CL, Müller A, Ottaway N, Sisley S, Smiley DL, Habegger KM, Pfluger PT, DiMarchi R, Biebermann H, Tschöp MH, Sandoval DA, Perez-Tilve D. Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors Diabetes. 63: 122-131. DOI: 10.2337/db13-0414  0.33
2013 Finan B, Ma T, Ottaway N, Müller TD, Habegger KM, Heppner KM, Kirchner H, Holland J, Hembree J, Raver C, Lockie SH, Smiley DL, Gelfanov V, Yang B, Hofmann S, et al. Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans Science Translational Medicine. 5. PMID 24174327 DOI: 10.1126/Scitranslmed.3007218  0.428
2013 Lehti M, Donelan E, Abplanalp W, Al-Massadi O, Habegger KM, Weber J, Ress C, Mansfeld J, Somvanshi S, Trivedi C, Keuper M, Ograjsek T, Striese C, Cucuruz S, Pfluger PT, et al. High-density lipoprotein maintains skeletal muscle function by modulating cellular respiration in mice. Circulation. 128: 2364-71. PMID 24170386 DOI: 10.1161/Circulationaha.113.001551  0.339
2013 Müller TD, Müller A, Yi CX, Habegger KM, Meyer CW, Gaylinn BD, Finan B, Heppner K, Trivedi C, Bielohuby M, Abplanalp W, Meyer F, Piechowski CL, Pratzka J, Stemmer K, et al. The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms. Nature Communications. 4: 1968. PMID 23744028 DOI: 10.1038/Ncomms2968  0.401
2013 Habegger KM, Stemmer K, Cheng C, Müller TD, Heppner KM, Ottaway N, Holland J, Hembree JL, Smiley D, Gelfanov V, Krishna R, Arafat AM, Konkar A, Belli S, Kapps M, et al. Fibroblast growth factor 21 mediates specific glucagon actions. Diabetes. 62: 1453-63. PMID 23305646 DOI: 10.2337/Db12-1116  0.416
2012 Habegger KM, Matzke D, Ottaway N, Hembree J, Holland J, Raver C, Mansfeld J, Müller TD, Perez-Tilve D, Pfluger PT, Lee SJ, Diaz-Meco M, Moscat J, Leitges M, Tschöp MH, et al. Role of adipose and hepatic atypical protein kinase C lambda (PKCλ) in the development of obesity and glucose intolerance. Adipocyte. 1: 203-214. PMID 23700535 DOI: 10.4161/adip.20891  0.425
2012 Nogueiras R, Habegger KM, Chaudhary N, Finan B, Banks AS, Dietrich MO, Horvath TL, Sinclair DA, Pfluger PT, Tschöp MH. Sirtuin 1 and sirtuin 3: physiological modulators of metabolism. Physiological Reviews. 92: 1479-514. PMID 22811431 DOI: 10.1152/Physrev.00022.2011  0.323
2012 Kirchner H, Hofmann SM, Fischer-Rosinský A, Hembree J, Abplanalp W, Ottaway N, Donelan E, Krishna R, Woods SC, Müller TD, Spranger J, Perez-Tilve D, Pfluger PT, Tschöp MH, Habegger KM. Caloric restriction chronically impairs metabolic programming in mice. Diabetes. 61: 2734-42. PMID 22787140 DOI: 10.2337/Db11-1621  0.371
2012 Müller TD, Sullivan LM, Habegger K, Yi CX, Kabra D, Grant E, Ottaway N, Krishna R, Holland J, Hembree J, Perez-Tilve D, Pfluger PT, DeGuzman MJ, Siladi ME, Kraynov VS, et al. Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 383-93. PMID 22565812 DOI: 10.1002/Psc.2408  0.312
2012 Habegger KM, Hoffman NJ, Ridenour CM, Brozinick JT, Elmendorf JS. AMPK enhances insulin-stimulated GLUT4 regulation via lowering membrane cholesterol. Endocrinology. 153: 2130-41. PMID 22434076 DOI: 10.1210/En.2011-2099  0.84
2012 Yi CX, Heppner KM, Kirchner H, Tong J, Bielohuby M, Gaylinn BD, Müller TD, Bartley E, Davis HW, Zhao Y, Joseph A, Kruthaupt T, Ottaway N, Kabra D, Habegger KM, et al. The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction. Plos One. 7: e32100. PMID 22363801 DOI: 10.1371/Journal.Pone.0032100  0.43
2012 Habegger KM, Penque BA, Sealls W, Tackett L, Bell LN, Blue EK, Gallagher PJ, Sturek M, Alloosh MA, Steinberg HO, Considine RV, Elmendorf JS. Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle. Diabetologia. 55: 457-67. PMID 22002007 DOI: 10.1007/S00125-011-2334-Y  0.805
2011 Habegger KM, Grant E, Pfluger PT, Perez-Tilve D, Daugherty A, Bruemmer D, Tschöp MH, Hofmann SM. Ghrelin Receptor Deficiency does not Affect Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Null Mice. Frontiers in Endocrinology. 2: 67. PMID 22649381 DOI: 10.3389/Fendo.2011.00067  0.36
2011 Bhonagiri P, Pattar GR, Habegger KM, McCarthy AM, Tackett L, Elmendorf JS. Evidence coupling increased hexosamine biosynthesis pathway activity to membrane cholesterol toxicity and cortical filamentous actin derangement contributing to cellular insulin resistance. Endocrinology. 152: 3373-84. PMID 21712361 DOI: 10.1210/En.2011-1295  0.788
2011 Yi CX, Habegger KM, Chowen JA, Stern J, Tschöp MH. A role for astrocytes in the central control of metabolism. Neuroendocrinology. 93: 143-9. PMID 21372559 DOI: 10.1159/000324888  0.336
2010 Habegger KM, Heppner KM, Geary N, Bartness TJ, DiMarchi R, Tschöp MH. The metabolic actions of glucagon revisited. Nature Reviews. Endocrinology. 6: 689-97. PMID 20957001 DOI: 10.1038/Nrendo.2010.187  0.451
2010 Heppner KM, Habegger KM, Day J, Pfluger PT, Perez-Tilve D, Ward B, Gelfanov V, Woods SC, DiMarchi R, Tschöp M. Glucagon regulation of energy metabolism. Physiology & Behavior. 100: 545-8. PMID 20381509 DOI: 10.1016/J.Physbeh.2010.03.019  0.476
2010 Bhonagiri P, Pattar GR, Horvath EM, Habegger KM, McCarthy AM, Elmendorf JS. Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin (Endocrinology (2009) 150, (1636-1645) DOI: 10.1210/en.2008-1102) Endocrinology. 151: 2967. DOI: 10.1210/En.2010-0489  0.768
2009 Bhonagiri P, Pattar GR, Horvath EM, Habegger KM, McCarthy AM, Elmendorf JS. Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin. Endocrinology. 150: 1636-45. PMID 19036880 DOI: 10.1210/En.2008-1102  0.787
2006 Habegger KM, Horvath EM, Elmendorf JS. DNP-Stimulated GLUT4 Translocation via 5???-AMP Activated Protein Kinase is Dependent on Plasma Membrane Cholesterol and Potentially Coupled Phosphoinositide-Regulated Actin Polymerization Events Medicine & Science in Sports & Exercise. 38: S8. DOI: 10.1249/00005768-200611001-00031  0.69
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