Hideyuki Okano - Publications

Affiliations: 
Keio University School of Medicine, Shinjuku-ku, Tōkyō-to, Japan 

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Year Citation  Score
2023 Ono-Minagi H, Nohno T, Serizawa T, Usami Y, Sakai T, Okano H, Ohuchi H. The Germinal Origin of Salivary and Lacrimal Glands and the Contributions of Neural Crest Cell-Derived Epithelium to Tissue Regeneration. International Journal of Molecular Sciences. 24. PMID 37761995 DOI: 10.3390/ijms241813692  0.339
2023 Okano H. Two major mechanisms regulating cell-fate decisions in the developing nervous system. Development, Growth & Differentiation. 37: 619-629. PMID 37281388 DOI: 10.1046/j.1440-169X.1995.t01-5-00001.x  0.409
2022 Namiki J, Suzuki S, Shibata S, Kubota Y, Kaneko N, Yoshida K, Yamaguchi R, Matsuzaki Y, Masuda T, Ishihama Y, Sawamoto K, Okano H. Chitinase-like protein 3: A novel niche factor for mouse neural stem cells. Stem Cell Reports. PMID 36368330 DOI: 10.1016/j.stemcr.2022.10.012  0.684
2022 Morimoto Y, Tokumitsu A, Sone T, Hirota Y, Tamura R, Sakamoto A, Nakajima K, Toda M, Kawakami Y, Okano H, Ohta S. TPT1 Supports Proliferation of Neural Stem/Progenitor Cells and Brain Tumor Initiating Cells Regulated by Macrophage Migration Inhibitory Factor (MIF). Neurochemical Research. PMID 35622214 DOI: 10.1007/s11064-022-03629-6  0.354
2021 Chen Y, Sakurai K, Maeda S, Masui T, Okano H, Dewender J, Seltmann S, Kurtz A, Masuya H, Nakamura Y, Sheldon M, Schneider J, Stacey GN, Panina Y, Fujibuchi W. Integrated Collection of Stem Cell Bank Data, a Data Portal for Standardized Stem Cell Information. Stem Cell Reports. PMID 33740463 DOI: 10.1016/j.stemcr.2021.02.014  0.454
2020 Al-Bakri Z, Ishige-Wada M, Fukuda N, Yoshida-Noro C, Nagoshi N, Okano H, Mugishima H, Matsumoto T. Isolation and characterization of neural crest-like progenitor cells in human umbilical cord blood. Regenerative Therapy. 15: 53-63. PMID 33426202 DOI: 10.1016/J.Reth.2020.06.001  0.402
2020 Harada S, Mabuchi Y, Kohyama J, Shimojo D, Suzuki S, Kawamura Y, Araki D, Suyama T, Kajikawa M, Akazawa C, Okano H, Matsuzaki Y. FZD5 regulates cellular senescence in human mesenchymal stem/stromal cells. Stem Cells (Dayton, Ohio). PMID 33338299 DOI: 10.1002/stem.3317  0.313
2020 Okano H, Sipp D. New trends in cellular therapy. Development (Cambridge, England). 147. PMID 32943426 DOI: 10.1242/Dev.192567  0.323
2020 Kase Y, Okano H. Expression of ACE2 and a viral virulence-regulating factor CCN family member 1 in human iPSC-derived neural cells: implications for COVID-19-related CNS disorders. Inflammation and Regeneration. 40: 32. PMID 32934757 DOI: 10.1186/S41232-020-00143-6  0.378
2020 Kajikawa K, Imaizumi K, Shinozaki M, Shibata S, Shindo T, Kitagawa T, Shibata R, Kamata Y, Kojima K, Nagoshi N, Matsumoto M, Nakamura M, Okano H. Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells. Molecular Brain. 13: 120. PMID 32883317 DOI: 10.1186/S13041-020-00662-W  0.333
2020 Saito K, Michon F, Yamada A, Inuzuka H, Yamaguchi S, Fukumoto E, Yoshizaki K, Nakamura T, Arakaki M, Chiba Y, Ishikawa M, Okano H, Thesleff I, Fukumoto S. Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ. Iscience. 23: 101329. PMID 32674056 DOI: 10.1016/J.Isci.2020.101329  0.36
2020 Yamane M, Sato S, Shimizu E, Shibata S, Hayano M, Yaguchi T, Kamijuku H, Ogawa M, Suzuki T, Mukai S, Shimmura S, Okano H, Takeuchi T, Kawakami Y, Ogawa Y, et al. Senescence-associated secretory phenotype promotes chronic ocular graft-vs-host disease in mice and humans. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32619061 DOI: 10.1096/Fj.201900218R  0.314
2020 Kase Y, Shimazaki T, Okano H. Current understanding of adult neurogenesis in the mammalian brain: how does adult neurogenesis decrease with age? Inflammation and Regeneration. 40: 10. PMID 32566044 DOI: 10.1186/S41232-020-00122-X  0.35
2020 Heide M, Haffner C, Murayama A, Kurotaki Y, Shinohara H, Okano H, Sasaki E, Huttner WB. Human-specific increases size and folding of primate neocortex in the fetal marmoset. Science (New York, N.Y.). PMID 32554627 DOI: 10.1126/Science.Abb2401  0.321
2020 Teratani T, Mikami Y, Nakamoto N, Suzuki T, Harada Y, Okabayashi K, Hagihara Y, Taniki N, Kohno K, Sibata S, Miyamoto K, Ishigame H, Chu PS, Sujino T, Suda W, ... ... Okano H, et al. The liver-brain-gut neural arc maintains the T cell niche in the gut. Nature. PMID 32526765 DOI: 10.1038/S41586-020-2425-3  0.352
2020 Tsujimura T, Takase O, Yoshikawa M, Sano E, Hayashi M, Hoshi K, Takato T, Toyoda A, Okano H, Hishikawa K. Controlling gene activation by enhancers through a drug-inducible topological insulator. Elife. 9. PMID 32369019 DOI: 10.7554/Elife.47980  0.358
2020 Hosoya M, Fujioka M, Murayama AY, Okano H, Ogawa K. The common marmoset as suitable non-human alternative for the analysis of primate cochlear development. The Febs Journal. PMID 32323465 DOI: 10.1111/Febs.15341  0.33
2020 Popovitchenko T, Park Y, Page NF, Luo X, Krsnik Z, Liu Y, Salamon I, Stephenson JD, Kraushar ML, Volk NL, Patel SM, Wijeratne HRS, Li D, Suthar KS, Wach A, ... ... Okano H, et al. Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development. Nature Communications. 11: 1674. PMID 32245946 DOI: 10.1038/S41467-020-15412-8  0.334
2020 Shiozawa S, Nakajima M, Okahara J, Kuortaki Y, Kisa F, Yoshimatsu S, Nakamura M, Koya I, Yoshimura M, Sasagawa Y, Nikaido I, Sasaki E, Okano H. Primed to naïve-like conversion of the common marmoset embryonic stem cells. Stem Cells and Development. PMID 32188344 DOI: 10.1089/Scd.2019.0259  0.365
2020 Yoshimatsu S, Sato T, Yamamoto M, Sasaki E, Nakajima M, Nakamura M, Shiozawa S, Noce T, Okano H. Generation of a male common marmoset embryonic stem cell line DSY127-BV8VT1 carrying double reporters specific for the germ cell linage using the CRISPR-Cas9 and PiggyBac transposase systems. Stem Cell Research. 44: 101740. PMID 32151954 DOI: 10.1016/J.Scr.2020.101740  0.386
2020 Adams A, Albin S, Amunts K, Asakawa T, Bernard A, Bjaalie JG, Chakli K, Deshler JO, Koninck YD, Ebell CJ, Egan G, Hale ME, Häusser M, Jeong SJ, Illes J, ... ... Okano H, et al. Erratum: International Brain Initiative: An Innovative Framework for Coordinated Global Brain Research Efforts (Neuron (2020) 105(2) (212–216), (S0896627320300027), (10.1016/j.neuron.2020.01.002)) Neuron. 105. PMID 32135092 DOI: 10.1016/J.Neuron.2020.02.022  0.319
2020 Ishikawa M, Aoyama T, Shibata S, Sone T, Miyoshi H, Watanabe H, Nakamura M, Morota S, Uchino H, Yoo AS, Okano H. miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro. Cells. 9. PMID 32106535 DOI: 10.3390/Cells9030532  0.376
2020 Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, ... ... Okano H, et al. Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nature Communications. 11: 859. PMID 32103003 DOI: 10.1038/S41467-020-14697-Z  0.309
2020 Tamura R, Miyoshi H, Morimoto Y, Oishi Y, Sampetrean O, Iwasawa C, Mine Y, Saya H, Yoshida K, Okano H, Toda M. Gene Therapy Using Neural Stem/Progenitor Cells Derived from Human Induced Pluripotent Stem Cells: Visualization of Migration and Bystander Killing Effect. Human Gene Therapy. PMID 32075424 DOI: 10.1089/Hum.2019.326  0.411
2020 Onodera K, Shimojo D, Ishihara Y, Yano M, Miya F, Banno H, Kuzumaki N, Ito T, Okada R, de Araújo Herculano B, Ohyama M, Yoshida M, Tsunoda T, Katsuno M, Doyu M, ... ... Okano H, et al. Unveiling synapse pathology in spinal bulbar muscular atrophy by genome-wide transcriptome analysis of purified motor neurons derived from disease specific iPSCs. Molecular Brain. 13: 18. PMID 32070397 DOI: 10.1186/S13041-020-0561-1  0.337
2020 Lin ZY, Nakai R, Hirai H, Kozuka D, Katayama S, Nakamura SI, Okada S, Kitajima R, Imai H, Okano H, Imamura M. Reprogramming of chimpanzee fibroblasts into a multipotent cancerous but not fully pluripotent state by transducing iPSC factors in 2i/LIF culture. Differentiation; Research in Biological Diversity. 112: 67-76. PMID 32045848 DOI: 10.1016/J.Diff.2020.01.002  0.398
2020 Tanimoto Y, Yamasaki T, Nagoshi N, Nishiyama Y, Nori S, Nishimura S, Iida T, Ozaki M, Tsuji O, Ji B, Aoki I, Jinzaki M, Matsumoto M, Fujibayashi Y, Zhang MR, ... ... Okano H, et al. In vivo monitoring of remnant undifferentiated neural cells following human iPS cell-derived neural stem/progenitor cells transplantation. Stem Cells Translational Medicine. PMID 31904914 DOI: 10.1002/Sctm.19-0150  0.409
2019 Tamura R, Miyoshi H, Yoshida K, Okano H, Toda M. Recent progress in the research of suicide gene therapy for malignant glioma. Neurosurgical Review. PMID 31781985 DOI: 10.1007/S10143-019-01203-3  0.333
2019 Kinoshita M, Fujimoto C, Iwasaki S, Kashio A, Kikkawa YS, Kondo K, Okano H, Yamasoba T. Alteration of Musashi1 Intra-cellular Distribution During Regeneration Following Gentamicin-Induced Hair Cell Loss in the Guinea Pig Crista Ampullaris. Frontiers in Cellular Neuroscience. 13: 481. PMID 31708751 DOI: 10.3389/Fncel.2019.00481  0.352
2019 Lam M, Sanosaka T, Lundin A, Imaizumi K, Etal D, Karlsson FH, Clausen M, Cairns J, Hicks R, Kohyama J, Kele M, Okano H, Falk A. Single cell study of neural stem cells derived from human iPSCs reveal distinct progenitor populations with neurogenic and gliogenic potential. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 31651061 DOI: 10.1111/Gtc.12731  0.408
2019 Arai Y, Cwetsch AW, Coppola E, Cipriani S, Nishihara H, Kanki H, Saillour Y, Freret-Hodara B, Dutriaux A, Okada N, Okano H, Dehay C, Nardelli J, Gressens P, Shimogori T, et al. Evolutionary Gain of Dbx1 Expression Drives Subplate Identity in the Cerebral Cortex. Cell Reports. 29: 645-658.e5. PMID 31618633 DOI: 10.1016/J.Celrep.2019.09.007  0.381
2019 Serizawa T, Isotani A, Matsumura T, Nakanishi K, Nonaka S, Shibata S, Ikawa M, Okano H. Developmental analyses of mouse embryos and adults using a non-overlapping tracing system for all three germ layers. Development (Cambridge, England). PMID 31597657 DOI: 10.1242/Dev.174938  0.369
2019 Yoshimatsu S, Nakamura M, Nakajima M, Nemoto A, Sato T, Sasaki E, Shiozawa S, Okano H. Evaluating the efficacy of small molecules for neural differentiation of common marmoset ESCs and iPSCs. Neuroscience Research. PMID 31586586 DOI: 10.1016/J.Neures.2019.09.005  0.418
2019 Nakamura M, Shiozawa S, Tsuboi D, Amano M, Watanabe H, Maeda S, Kimura T, Yoshimatsu S, Kisa F, Karch CM, Miyasaka T, Takashima A, Sahara N, Hisanaga SI, Ikeuchi T, ... ... Okano H, et al. Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs. Stem Cell Reports. PMID 31543469 DOI: 10.1016/J.Stemcr.2019.08.011  0.309
2019 Yoshimatsu S, Sone T, Nakajima M, Sato T, Okochi R, Ishikawa M, Nakamura M, Sasaki E, Shiozawa S, Okano H. A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology. Plos One. 14: e0221164. PMID 31454364 DOI: 10.1371/Journal.Pone.0221164  0.32
2019 Cheng YF, Chan YH, Hu CJ, Lu YC, Saeki T, Hosoya M, Saegusa C, Fujioka M, Okano H, Weng SM, Hsu CJ, Chang KH, Wu CC. Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation. Stem Cell Research. 40: 101524. PMID 31415960 DOI: 10.1016/J.Scr.2019.101524  0.332
2019 Abe Y, Ochiai D, Masuda H, Sato Y, Otani T, Fukutake M, Ikenoue S, Miyakoshi K, Okano H, Tanaka M. In Utero Amniotic Fluid Stem Cell Therapy Protects Against Myelomeningocele via Spinal Cord Coverage and Hepatocyte Growth Factor Secretion. Stem Cells Translational Medicine. PMID 31407874 DOI: 10.1002/Sctm.19-0002  0.369
2019 Morimoto S, Takahashi S, Fukushima K, Saya H, Suzuki N, Aoki M, Okano H, Nakahara J. Ropinirole hydrochloride remedy for amyotrophic lateral sclerosis - Protocol for a randomized, double-blind, placebo-controlled, single-center, and open-label continuation phase I/IIa clinical trial (ROPALS trial). Regenerative Therapy. 11: 143-166. PMID 31384636 DOI: 10.1016/J.Reth.2019.07.002  0.307
2019 Tabata Y, Okano H. [Modeling Familial Parkinson's Disease Using Patient-specific Induced Pluripotent Stem Cells]. Brain and Nerve = Shinkei Kenkyu No Shinpo. 71: 875-883. PMID 31346144 DOI: 10.11477/Mf.1416201368  0.309
2019 Sone T, Shin M, Ouchi T, Sasanuma H, Miyamoto A, Ohte S, Tsukamoto S, Nakanishi M, Okano H, Katagiri T, Mitani K. Dual usage of a stage-specific fluorescent reporter system based on a helper-dependent adenoviral vector to visualize osteogenic differentiation. Scientific Reports. 9: 9705. PMID 31273280 DOI: 10.1038/S41598-019-46105-Y  0.359
2019 Nagoshi N, Tsuji O, Nakamura M, Okano H. Cell therapy for spinal cord injury using induced pluripotent stem cells. Regenerative Therapy. 11: 75-80. PMID 31245451 DOI: 10.1016/J.Reth.2019.05.006  0.37
2019 Kobayashi J, Hasegawa T, Sugeno N, Yoshida S, Akiyama T, Fujimori K, Hatakeyama H, Miki Y, Tomiyama A, Kawata Y, Fukuda M, Kawahata I, Yamakuni T, Ezura M, Kikuchi A, ... ... Okano H, et al. Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802051R. PMID 31211923 DOI: 10.1096/Fj.201802051R  0.302
2019 Nakajima M, Yoshimatsu S, Sato T, Nakamura M, Okahara J, Sasaki E, Shiozawa S, Okano H. Establishment of induced pluripotent stem cells from common marmoset fibroblasts by RNA-based reprogramming. Biochemical and Biophysical Research Communications. PMID 31178141 DOI: 10.1016/J.Bbrc.2019.05.175  0.358
2019 Kuzumaki N, Suda Y, Iwasawa C, Narita M, Sone T, Watanabe M, Maekawa A, Matsumoto T, Akamatsu W, Igarashi K, Tamura H, Takeshima H, Tawfik VL, Ushijima T, Hattori N, ... Okano H, et al. Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease. Brain : a Journal of Neurology. 142: 1675-1689. PMID 31135049 DOI: 10.1093/Brain/Awz084  0.364
2019 Kase Y, Otsu K, Shimazaki T, Okano H. Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling. Stem Cell Reports. PMID 31080114 DOI: 10.1016/J.Stemcr.2019.04.010  0.363
2019 Tamura R, Miyoshi H, Sampetrean O, Shinozaki M, Morimoto Y, Iwasawa C, Fukaya R, Mine Y, Masuda H, Maruyama T, Narita M, Saya H, Yoshida K, Okano H, Toda M. Visualization of spatiotemporal dynamics of human glioma stem cell invasion. Molecular Brain. 12: 45. PMID 31060588 DOI: 10.1186/S13041-019-0462-3  0.323
2019 Abe Y, Komaki Y, Seki F, Shibata S, Okano H, Tanaka KF. Correlative study using structural MRI and super-resolution microscopy to detect structural alterations induced by long-term optogenetic stimulation of striatal medium spiny neurons. Neurochemistry International. 125: 163-174. PMID 30825601 DOI: 10.1016/J.Neuint.2019.02.017  0.308
2019 Iwasawa C, Tamura R, Sugiura Y, Suzuki S, Kuzumaki N, Narita M, Suematsu M, Nakamura M, Yoshida K, Toda M, Okano H, Miyoshi H. Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells. International Journal of Molecular Sciences. 20. PMID 30769780 DOI: 10.3390/Ijms20040810  0.364
2019 Yoshimatsu S, Okahara J, Sone T, Takeda Y, Nakamura M, Sasaki E, Kishi N, Shiozawa S, Okano H. Robust and efficient knock-in in embryonic stem cells and early-stage embryos of the common marmoset using the CRISPR-Cas9 system. Scientific Reports. 9: 1528. PMID 30728412 DOI: 10.1038/S41598-018-37990-W  0.343
2019 Nishihara K, Shiga T, Nakamura E, Akiyama T, Sasaki T, Suzuki S, Ko MSH, Tada N, Okano H, Akamatsu W. Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker Expression. Stem Cell Reports. PMID 30713040 DOI: 10.1016/J.Stemcr.2018.12.018  0.405
2019 Iwasawa C, Kuzumaki N, Suda Y, Kagawa R, Oka Y, Hattori N, Okano H, Narita M. Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations. Molecular Brain. 12: 5. PMID 30658665 DOI: 10.1186/S13041-019-0426-7  0.317
2019 Hosoya M, Saeki T, Saegusa C, Matsunaga T, Okano H, Fujioka M, Ogawa K. Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome. Regenerative Therapy. 10: 54-63. PMID 30581897 DOI: 10.1016/J.Reth.2018.11.001  0.362
2018 Okubo T, Nagoshi N, Kohyama J, Tsuji O, Shinozaki M, Shibata S, Kase Y, Matsumoto M, Nakamura M, Okano H. Treatment with a Gamma-Secretase Inhibitor Promotes Functional Recovery in Human iPSC- Derived Transplants for Chronic Spinal Cord Injury. Stem Cell Reports. PMID 30503258 DOI: 10.1016/J.Stemcr.2018.10.022  0.354
2018 Kojima K, Miyoshi H, Nagoshi N, Kohyama J, Itakura G, Kawabata S, Ozaki M, Iida T, Sugai K, Ito S, Fukuzawa R, Yasutake K, Renault-Mihara F, Shibata S, Matsumoto M, ... ... Okano H, et al. Selective Ablation of Tumorigenic Cells Following Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in Spinal Cord Injury. Stem Cells Translational Medicine. PMID 30485733 DOI: 10.1002/Sctm.18-0096  0.391
2018 Tsuji O, Sugai K, Yamaguchi R, Tashiro S, Nagoshi N, Kohyama J, Iida T, Ohkubo T, Itakura G, Isoda M, Shinozaki M, Fujiyoshi K, Kanemura Y, Yamanaka S, Nakamura M, ... Okano H, et al. Laying the groundwork for a first-in-human study of an iPSC-based intervention for spinal cord injury. Stem Cells (Dayton, Ohio). PMID 30371964 DOI: 10.1002/Stem.2926  0.346
2018 Kuwako KI, Okano H. Versatile Roles of LKB1 Kinase Signaling in Neural Development and Homeostasis. Frontiers in Molecular Neuroscience. 11: 354. PMID 30333724 DOI: 10.3389/Fnmol.2018.00354  0.34
2018 Nakamoto FK, Okamoto S, Mitsui J, Sone T, Ishikawa M, Yamamoto Y, Kanegae Y, Nakatake Y, Imaizumi K, Ishiura H, Tsuji S, Okano H. The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy. Scientific Reports. 8: 14215. PMID 30242188 DOI: 10.1038/S41598-018-32573-1  0.326
2018 Fujimori K, Ishikawa M, Otomo A, Atsuta N, Nakamura R, Akiyama T, Hadano S, Aoki M, Saya H, Sobue G, Okano H. Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent. Nature Medicine. PMID 30127392 DOI: 10.1038/S41591-018-0140-5  0.328
2018 Arioka Y, Shishido E, Kubo H, Kushima I, Yoshimi A, Kimura H, Ishizuka K, Aleksic B, Maeda T, Ishikawa M, Kuzumaki N, Okano H, Mori D, Ozaki N. Single-cell trajectory analysis of human homogenous neurons carrying a rare RELN variant. Translational Psychiatry. 8: 129. PMID 30022058 DOI: 10.1038/S41398-018-0177-8  0.379
2018 Tanaka Y, Higurashi N, Shirasu N, Yasunaga S, Moreira KM, Okano H, Hirose S. Establishment of a human induced stem cell line (FUi002-A) from Dravet syndrome patient carrying heterozygous R1525X mutation in SCN1A gene. Stem Cell Research. 31: 11-15. PMID 29981888 DOI: 10.1016/J.Scr.2018.06.008  0.334
2018 Kimura H, Ouchi T, Shibata S, Amemiya T, Nagoshi N, Nakagawa T, Matsumoto M, Okano H, Nakamura M, Sato K. Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration. Scientific Reports. 8: 10071. PMID 29968745 DOI: 10.1038/S41598-018-27952-7  0.345
2018 Takata N, Sugiura Y, Yoshida K, Koizumi M, Hiroshi N, Honda K, Yano R, Komaki Y, Matsui K, Suematsu M, Mimura M, Okano H, Tanaka KF. Optogenetic astrocyte activation evokes BOLD fMRI response with oxygen consumption without neuronal activity modulation. Glia. PMID 29845643 DOI: 10.1002/Glia.23454  0.32
2018 Iwano S, Sugiyama M, Hama H, Watakabe A, Hasegawa N, Kuchimaru T, Tanaka KZ, Takahashi M, Ishida Y, Hata J, Shimozono S, Namiki K, Fukano T, Kiyama M, Okano H, et al. Single-cell bioluminescence imaging of deep tissue in freely moving animals. Science (New York, N.Y.). 359: 935-939. PMID 29472486 DOI: 10.1126/Science.Aaq1067  0.338
2018 Suda Y, Kuzumaki N, Sone T, Narita M, Tanaka K, Hamada Y, Iwasawa C, Shibasaki M, Maekawa A, Matsuo M, Akamatsu W, Hattori N, Okano H, Narita M. Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction. Molecular Brain. 11: 6. PMID 29458391 DOI: 10.1186/S13041-018-0349-8  0.336
2018 Nakatomi M, Quispe-Salcedo A, Sakaguchi M, Ida-Yonemochi H, Okano H, Ohshima H. Nestin expression is differently regulated between odontoblasts and the subodontoblastic layer in mice. Histochemistry and Cell Biology. PMID 29445893 DOI: 10.1007/S00418-018-1651-3  0.412
2018 Chai M, Sanosaka T, Okuno H, Zhou Z, Koya I, Banno S, Andoh-Noda T, Tabata Y, Shimamura R, Hayashi T, Ebisawa M, Sasagawa Y, Nikaido I, Okano H, Kohyama J. Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors. Genes & Development. PMID 29440260 DOI: 10.1101/Gad.301887.117  0.384
2018 Ogawa Y, Kakumoto K, Yoshida T, Kuwako KI, Miyazaki T, Yamaguchi J, Konno A, Hata J, Uchiyama Y, Hirai H, Watanabe M, Darnell RB, Okano H, Okano HJ. Elavl3 is essential for the maintenance of Purkinje neuron axons. Scientific Reports. 8: 2722. PMID 29426875 DOI: 10.1038/S41598-018-21130-5  0.341
2018 Takeda H, Hosoya M, Fujioka M, Saegusa C, Saeki T, Miwa T, Okano H, Minoda R. Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice. Scientific Reports. 8: 1941. PMID 29386634 DOI: 10.1038/S41598-018-20277-5  0.409
2018 Mao D, Chung XKW, Andoh-Noda T, Qin Y, Sato SI, Takemoto Y, Akamatsu W, Okano H, Uesugi M. Chemical decontamination of iPS cell-derived neural cell mixtures. Chemical Communications (Cambridge, England). PMID 29350722 DOI: 10.1039/C7Cc08686E  0.41
2017 Tateno H, Hiemori K, Hirayasu K, Sougawa N, Fukuda M, Warashina M, Amano M, Funakoshi T, Sadamura Y, Miyagawa S, Saito A, Sawa Y, Shofuda T, Sumida M, Kanemura Y, ... ... Okano H, et al. Development of a practical sandwich assay to detect human pluripotent stem cells using cell culture media. Regenerative Therapy. 6: 1-8. PMID 30271833 DOI: 10.1016/J.Reth.2016.12.002  0.386
2017 Bamba Y, Nonaka M, Sasaki N, Shofuda T, Kanematsu D, Suemizu H, Higuchi Y, Pooh RK, Kanemura Y, Okano H, Yamasaki M. Generation of Induced Pluripotent Stem Cells and Neural Stem/Progenitor Cells from Newborns with Spina Bifida Aperta. Asian Spine Journal. 11: 870-879. PMID 29279741 DOI: 10.4184/Asj.2017.11.6.870  0.377
2017 Yasui T, Mabuchi Y, Morikawa S, Onizawa K, Akazawa C, Nakagawa T, Okano H, Matsuzaki Y. Isolation of dental pulp stem cells with high osteogenic potential. Inflammation and Regeneration. 37: 8. PMID 29259707 DOI: 10.1186/S41232-017-0039-4  0.368
2017 Okuno H, Renault Mihara F, Ohta S, Fukuda K, Kurosawa K, Akamatsu W, Sanosaka T, Kohyama J, Hayashi K, Nakajima K, Takahashi T, Wysocka J, Kosaki K, Okano H. CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations. Elife. 6. PMID 29179815 DOI: 10.7554/Elife.21114  0.323
2017 Kisa F, Shiozawa S, Oda K, Yoshimatsu S, Nakamura M, Koya I, Kawai K, Suzuki S, Okano H. Naive-like ESRRB(+) iPSCs with the Capacity for Rapid Neural Differentiation. Stem Cell Reports. PMID 29129686 DOI: 10.1016/J.Stemcr.2017.10.008  0.414
2017 Shimogori T, Abe A, Go Y, Hashikawa T, Kishi N, Kikuchi SS, Kita Y, Niimi K, Nishibe H, Okuno M, Saga K, Sakurai M, Sato M, Serizawa T, Suzuki S, ... ... Okano H, et al. Digital gene atlas of neonate common marmoset brain. Neuroscience Research. PMID 29111135 DOI: 10.1016/J.Neures.2017.10.009  0.304
2017 Fujimori K, Matsumoto T, Kisa F, Hattori N, Okano H, Akamatsu W. Escape from Pluripotency via Inhibition of TGF-β/BMP and Activation of Wnt Signaling Accelerates Differentiation and Aging in hPSC Progeny Cells. Stem Cell Reports. 9: 1675-1691. PMID 29107593 DOI: 10.1016/J.Stemcr.2017.09.024  0.416
2017 Fukuhara S, Masaoka T, Nishimura S, Nakamura M, Matsuzaki J, Tsugawa H, Miyoshi S, Mori H, Kawase S, Shibata S, Okano H, Kanai T, Suzuki H. Enteric Glial Dysfunction Evoked by Apolipoprotein E Deficiency Contributes to Delayed Gastric Emptying. Digestive Diseases and Sciences. PMID 29098550 DOI: 10.1007/S10620-017-4820-7  0.309
2017 Matsuzaki S, Hosoya M, Okano H, Fujioka M, Ogawa K. Expression pattern of EYA4 in the common marmoset (Callithrix jacchus) cochlea. Neuroscience Letters. PMID 29054432 DOI: 10.1016/J.Neulet.2017.10.030  0.398
2017 Cartelli D, Amadeo A, Calogero AM, Casagrande FVM, De Gregorio C, Gioria M, Kuzumaki N, Costa I, Sassone J, Ciammola A, Hattori N, Okano H, Goldwurm S, Roybon L, Pezzoli G, et al. Parkin absence accelerates microtubule aging in dopaminergic neurons. Neurobiology of Aging. 61: 66-74. PMID 29040870 DOI: 10.1016/J.Neurobiolaging.2017.09.010  0.367
2017 Itakura G, Ozaki M, Nagoshi N, Kawabata S, Nishiyama Y, Sugai K, Iida T, Kashiwagi R, Ookubo T, Yastake K, Matsubayashi K, Kohyama J, Iwanami A, Matsumoto M, Nakamura M, ... Okano H, et al. Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells. Scientific Reports. 7: 12996. PMID 29021610 DOI: 10.1038/S41598-017-13522-W  0.392
2017 Hayakawa-Yano Y, Suyama S, Nogami M, Yugami M, Koya I, Furukawa T, Zhou L, Abe M, Sakimura K, Takebayashi H, Nakanishi A, Okano H, Yano M. An RNA-binding protein, Qki5, regulates embryonic neural stem cells through pre-mRNA processing in cell adhesion signaling. Genes & Development. PMID 29021239 DOI: 10.1101/Gad.300822.117  0.443
2017 Nagoshi N, Okano H. iPSC-derived neural precursor cells: potential for cell transplantation therapy in spinal cord injury. Cellular and Molecular Life Sciences : Cmls. PMID 28993834 DOI: 10.1007/S00018-017-2676-9  0.368
2017 Kodo K, Shibata S, Miyagawa-Tomita S, Ong SG, Takahashi H, Kume T, Okano H, Matsuoka R, Yamagishi H. Regulation of Sema3c and the Interaction between Cardiac Neural Crest and Second Heart Field during Outflow Tract Development. Scientific Reports. 7: 6771. PMID 28754980 DOI: 10.1038/S41598-017-06964-9  0.341
2017 Bamba Y, Kanemura Y, Okano H, Yamasaki M. Visualization of migration of human cortical neurons generated from induced pluripotent stem cells. Journal of Neuroscience Methods. PMID 28694214 DOI: 10.1016/J.Jneumeth.2017.07.004  0.347
2017 Morizawa YM, Hirayama Y, Ohno N, Shibata S, Shigetomi E, Sui Y, Nabekura J, Sato K, Okajima F, Takebayashi H, Okano H, Koizumi S. Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway. Nature Communications. 8: 28. PMID 28642575 DOI: 10.1038/S41467-017-00037-1  0.307
2017 Renault-Mihara F, Mukaino M, Shinozaki M, Kumamaru H, Kawase S, Baudoux M, Ishibashi T, Kawabata S, Nishiyama Y, Sugai K, Yasutake K, Okada S, Nakamura M, Okano H. Regulation of RhoA by STAT3 coordinates glial scar formation. The Journal of Cell Biology. PMID 28642362 DOI: 10.1083/Jcb.201610102  0.311
2017 Yasui T, Uezono N, Nakashima H, Noguchi H, Matsuda T, Noda-Andoh T, Okano H, Nakashima K. Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. Stem Cell Reports. 8: 1743-1756. PMID 28591654 DOI: 10.1016/J.Stemcr.2017.05.001  0.42
2017 Nori S, Nakamura M, Okano H. Plasticity and regeneration in the injured spinal cord after cell transplantation therapy. Progress in Brain Research. 231: 33-56. PMID 28554400 DOI: 10.1016/Bs.Pbr.2016.12.007  0.313
2017 Shiba-Fukushima K, Ishikawa KI, Inoshita T, Izawa N, Takanashi M, Sato S, Onodera O, Akamatsu W, Okano H, Imai Y, Hattori N. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease. Human Molecular Genetics. PMID 28541509 DOI: 10.1093/Hmg/Ddx201  0.317
2017 Ishikawa KI, Yamaguchi A, Okano H, Akamatsu W. Assessment of Mitophagy in iPS Cell-Derived Neurons. Methods in Molecular Biology (Clifton, N.J.). PMID 28324490 DOI: 10.1007/7651_2017_10  0.371
2017 Itakura G, Kawabata S, Ando M, Nishiyama Y, Sugai K, Ozaki M, Iida T, Ookubo T, Kojima K, Kashiwagi R, Yasutake K, Nakauchi H, Miyoshi H, Nagoshi N, Kohyama J, ... ... Okano H, et al. Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives. Stem Cell Reports. PMID 28262544 DOI: 10.1016/J.Stemcr.2017.02.003  0.369
2017 Veraitch O, Mabuchi Y, Matsuzaki Y, Sasaki T, Okuno H, Tsukashima A, Amagai M, Okano H, Ohyama M. Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells. Scientific Reports. 7: 42777. PMID 28220862 DOI: 10.1038/Srep42777  0.409
2017 Sato R, Nakano T, Hosonaga M, Sampetrean O, Harigai R, Sasaki T, Koya I, Okano H, Kudoh J, Saya H, Arima Y. RNA Sequencing Analysis Reveals Interactions between Breast Cancer or Melanoma Cells and the Tissue Microenvironment during Brain Metastasis. Biomed Research International. 2017: 8032910. PMID 28210624 DOI: 10.1155/2017/8032910  0.315
2017 Nagoshi N, Okano H. Applications of induced pluripotent stem cell technologies in spinal cord injury. Journal of Neurochemistry. PMID 28199003 DOI: 10.1111/Jnc.13986  0.393
2017 Inagaki E, Hatou S, Higa K, Yoshida S, Shibata S, Okano H, Tsubota K, Shimmura S. Skin-Derived Precursors as a Source of Progenitors for Corneal Endothelial Regeneration. Stem Cells Translational Medicine. PMID 28186681 DOI: 10.1002/Sctm.16-0162  0.372
2017 Tsutsui-Kimura I, Takiue H, Yoshida K, Xu M, Yano R, Ohta H, Nishida H, Bouchekioua Y, Okano H, Uchigashima M, Watanabe M, Takata N, Drew MR, Sano H, Mimura M, et al. Dysfunction of ventrolateral striatal dopamine receptor type 2-expressing medium spiny neurons impairs instrumental motivation. Nature Communications. 8: 14304. PMID 28145402 DOI: 10.1038/Ncomms14304  0.304
2017 Ozaki M, Iwanami A, Nagoshi N, Kohyama J, Itakura G, Iwai H, Nishimura S, Nishiyama Y, Kawabata S, Sugai K, Iida T, Matsubayashi K, Isoda M, Kashiwagi R, Toyama Y, ... ... Okano H, et al. Evaluation of the immunogenicity of human iPS cell-derived neural stem/progenitor cells in vitro. Stem Cell Research. 19: 128-138. PMID 28135684 DOI: 10.1016/J.Scr.2017.01.007  0.338
2017 Takayama Y, Wakabayashi T, Kushige H, Saito Y, Shibuya Y, Shibata S, Akamatsu W, Okano H, Kida YS. Brief Exposure to Small Molecules Allows Induction of Mouse Embryonic Fibroblasts into Neural Crest-Like Precursors. Febs Letters. PMID 28129669 DOI: 10.1002/1873-3468.12572  0.425
2017 Suzuki S, Akamatsu W, Kisa F, Sone T, Ishikawa KI, Kuzumaki N, Katayama H, Miyawaki A, Hattori N, Okano H. Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons. Biochemical and Biophysical Research Communications. PMID 28057485 DOI: 10.1016/J.Bbrc.2016.12.188  0.37
2017 Hosoya M, Fujioka M, Sone T, Okamoto S, Akamatsu W, Ukai H, Ueda HR, Ogawa K, Matsunaga T, Okano H. Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss. Cell Reports. 18: 68-81. PMID 28052261 DOI: 10.1016/J.Celrep.2016.12.020  0.33
2017 Ouchi T, Shibata S, Kimura H, Nagoshi N, Fujimura T, Morikawa S, Sato K, Kawana H, Fukuda K, Nakamura M, Nakagawa T, Okano H. LNGFR (+) THY-1 (+) multipotent stem cells derived from human induced pluripotent stem cells Mechanisms of Development. 145: S169-S170. DOI: 10.1016/J.Mod.2017.04.490  0.349
2016 Okano H. A new era for Inflammation and Regeneration. Inflammation and Regeneration. 36: 3. PMID 29259676 DOI: 10.1186/S41232-016-0003-8  0.321
2016 Nakazawa T, Kikuchi M, Ishikawa M, Yamamori H, Nagayasu K, Matsumoto T, Fujimoto M, Yasuda Y, Fujiwara M, Okada S, Matsumura K, Kasai A, Hayata-Takano A, Shintani N, Numata S, ... ... Okano H, et al. Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. Schizophrenia Research. PMID 28277309 DOI: 10.1016/J.Schres.2016.10.012  0.308
2016 Yamazaki K, Fukushima K, Sugawara M, Tabata Y, Imaizumi Y, Ishihara Y, Ito M, Tsukahara K, Kohyama J, Okano H. Functional Comparison of Neuronal Cells Differentiated from Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Different Oxygen and Medium Conditions. Journal of Biomolecular Screening. 21: 1054-1064. PMID 28139961 DOI: 10.1177/1087057116661291  0.388
2016 Ohta S, Yaguchi T, Okuno H, Chneiweiss H, Kawakami Y, Okano H. CHD7 promotes proliferation of neural stem cells mediated by MIF. Molecular Brain. 9: 96. PMID 27955690 DOI: 10.1186/S13041-016-0275-6  0.455
2016 Sato Y, Mabuchi Y, Miyamoto K, Araki D, Niibe K, Houlihan DD, Morikawa S, Nakagawa T, Nakajima T, Akazawa C, Hori S, Okano H, Matsuzaki Y. Notch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression. Plos One. 11: e0165946. PMID 27855169 DOI: 10.1371/Journal.Pone.0165946  0.369
2016 Toyoshima M, Akamatsu W, Okada Y, Ohnishi T, Balan S, Hisano Y, Iwayama Y, Toyota T, Matsumoto T, Itasaka N, Sugiyama S, Tanaka M, Yano M, Dean B, Okano H, et al. Analysis of induced pluripotent stem cells carrying 22q11.2 deletion. Translational Psychiatry. 6: e934. PMID 27801899 DOI: 10.1038/Tp.2016.206  0.331
2016 Fujimori K, Tezuka T, Ishiura H, Mitsui J, Doi K, Yoshimura J, Tada H, Matsumoto T, Isoda M, Hashimoto R, Hattori N, Takahashi T, Morishita S, Tsuji S, Akamatsu W, ... Okano H, et al. Modeling neurological diseases with induced pluripotent cells reprogrammed from immortalized lymphoblastoid cell lines. Molecular Brain. 9: 88. PMID 27716287 DOI: 10.1186/S13041-016-0267-6  0.338
2016 Okubo T, Iwanami A, Kohyama J, Itakura G, Kawabata S, Nishiyama Y, Sugai K, Ozaki M, Iida T, Matsubayashi K, Matsumoto M, Nakamura M, Okano H. Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury. Stem Cell Reports. PMID 27666789 DOI: 10.1016/J.Stemcr.2016.08.015  0.386
2016 Imamura T, Fujita K, Tagawa K, Ikura T, Chen X, Homma H, Tamura T, Mao Y, Taniguchi JB, Motoki K, Nakabayashi M, Ito N, Yamada K, Tomii K, Okano H, et al. Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries. Scientific Reports. 6: 33861. PMID 27653664 DOI: 10.1038/Srep33861  0.306
2016 Nakajima R, Okano H, Noce T. JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis. Plos One. 11: e0163466. PMID 27649575 DOI: 10.1371/Journal.Pone.0163466  0.35
2016 Sugai K, Fukuzawa R, Shofuda T, Fukusumi H, Kawabata S, Nishiyama Y, Higuchi Y, Kawai K, Isoda M, Kanematsu D, Hashimoto-Tamaoki T, Kohyama J, Iwanami A, Suemizu H, Ikeda E, ... ... Okano H, et al. Pathological classification of human iPSC-derived neural stem/progenitor cells towards safety assessment of transplantation therapy for CNS diseases. Molecular Brain. 9: 85. PMID 27642008 DOI: 10.1186/S13041-016-0265-8  0.383
2016 Cheung LY, Okano H, Camper SA. Sox21 deletion in mice causes postnatal growth deficiency without physiological disruption of hypothalamic-pituitary endocrine axes. Molecular and Cellular Endocrinology. PMID 27616671 DOI: 10.1016/J.Mce.2016.09.005  0.305
2016 Tashiro S, Nishimura S, Iwai H, Sugai K, Zhang L, Shinozaki M, Iwanami A, Toyama Y, Liu M, Okano H, Nakamura M. Functional Recovery from Neural Stem/Progenitor Cell Transplantation Combined with Treadmill Training in Mice with Chronic Spinal Cord Injury. Scientific Reports. 6: 30898. PMID 27485458 DOI: 10.1038/Srep30898  0.317
2016 Bamba Y, Shofuda T, Kato M, Pooh RK, Tateishi Y, Takanashi J, Utsunomiya H, Sumida M, Kanematsu D, Suemizu H, Higuchi Y, Akamatsu W, Gallagher D, Miller FD, Yamasaki M, ... ... Okano H, et al. In vitro characterization of neurite extension using induced pluripotent stem cells derived from lissencephaly patients with TUBA1A missense mutations. Molecular Brain. 9: 70. PMID 27431206 DOI: 10.1186/S13041-016-0246-Y  0.354
2016 Hosoya M, Fujioka M, Okano H, Ogawa K. Distinct Expression Pattern of a Deafness Gene, KIAA1199, in a Primate Cochlea. Biomed Research International. 2016: 1781894. PMID 27403418 DOI: 10.1155/2016/1781894  0.356
2016 Suzuki N, Hosoya M, Oishi N, Okano H, Fujioka M, Ogawa K. Expression pattern of wolframin, the WFS1 (Wolfram syndrome-1 gene) product, in common marmoset (Callithrix jacchus) cochlea. Neuroreport. PMID 27341211 DOI: 10.1097/Wnr.0000000000000624  0.347
2016 Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp JL, Kritzik M, Sicklick JK, Sander M, Grandgenett PM, Hollingsworth MA, ... ... Okano H, et al. Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature. PMID 27281208 DOI: 10.1038/Nature17988  0.302
2016 Kunitomi A, Yuasa S, Sugiyama F, Saito Y, Seki T, Kusumoto D, Kashimura S, Takei M, Tohyama S, Hashimoto H, Egashira T, Tanimoto Y, Mizuno S, Tanaka S, Okuno H, ... ... Okano H, et al. H1foo Has a Pivotal Role in Qualifying Induced Pluripotent Stem Cells. Stem Cell Reports. PMID 27237376 DOI: 10.1016/J.Stemcr.2016.04.015  0.375
2016 Fukusumi H, Shofuda T, Bamba Y, Yamamoto A, Kanematsu D, Handa Y, Okita K, Nakamura M, Yamanaka S, Okano H, Kanemura Y. Establishment of Human Neural Progenitor Cells from Human Induced Pluripotent Stem Cells with Diverse Tissue Origins. Stem Cells International. 2016: 7235757. PMID 27212953 DOI: 10.1155/2016/7235757  0.411
2016 Ouchi T, Morikawa S, Shibata S, Fukuda K, Okuno H, Fujimura T, Kuroda T, Ohyama M, Akamatsu W, Nakagawa T, Okano H. LNGFR(+)THY-1(+) human pluripotent stem cell-derived neural crest-like cells have the potential to develop into mesenchymal stem cells. Differentiation; Research in Biological Diversity. PMID 27178356 DOI: 10.1016/J.Diff.2016.04.003  0.418
2016 Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, Koya I, Okada Y, Kimura T, Tsuchiya Y, Suzuki S, Onishi N, Kuzumaki N, Matsuzaki Y, Narita M, ... ... Okano H, et al. Tumour resistance in induced pluripotent stem cells derived from naked mole-rats. Nature Communications. 7: 11471. PMID 27161380 DOI: 10.1038/Ncomms11471  0.347
2016 Bertolin AP, Katz MJ, Yano M, Pozzi B, Acevedo JM, Blanco-Obregón D, Gándara L, Sorianello E, Kanda H, Okano H, Srebrow A, Wappner P. Musashi mediates translational repression of the Drosophila hypoxia inducible factor. Nucleic Acids Research. PMID 27141964 DOI: 10.1093/Nar/Gkw372  0.3
2016 Isoda M, Kohyama J, Iwanami A, Sanosaka T, Sugai K, Yamaguchi R, Matsumoto T, Nakamura M, Okano H. Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions. Neuroscience Research. PMID 27083781 DOI: 10.1016/J.Neures.2016.04.003  0.414
2016 Andoh-Noda T, Inouye MO, Miyake K, Kubota T, Okano H, Akamatsu W. Modeling Rett syndrome using human induced pluripotent stem cells. Cns & Neurological Disorders Drug Targets. PMID 27071793 DOI: 10.2174/1871527315666160413120156  0.399
2016 Morikawa S, Ouchi T, Shibata S, Fujimura T, Kawana H, Okano H, Nakagawa T. Applications of Mesenchymal Stem Cells and Neural Crest Cells in Craniofacial Skeletal Research. Stem Cells International. 2016: 2849879. PMID 27006661 DOI: 10.1155/2016/2849879  0.392
2016 Ichiyanagi N, Fujimori K, Yano M, Ishihara-Fujisaki C, Sone T, Akiyama T, Okada Y, Akamatsu W, Matsumoto T, Ishikawa M, Nishimoto Y, Ishihara Y, Sakuma T, Yamamoto T, Tsuiji H, ... ... Okano H, et al. Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells. Stem Cell Reports. PMID 26997647 DOI: 10.1016/J.Stemcr.2016.02.011  0.363
2016 Fukaya R, Ohta S, Yaguchi T, Matsuzaki Y, Sugihara E, Okano H, Saya H, Kawakami Y, Kawase T, Yoshida K, Toda M. MIF maintains the tumorigenic capacity of brain tumor-initiating cells by directly inhibiting p53. Cancer Research. PMID 26980763 DOI: 10.1158/0008-5472.Can-15-1011  0.37
2016 Fujimura T, Shibata S, Shimojima N, Morikawa Y, Okano H, Kuroda T. Fluorescence Visualization of the Enteric Nervous Network in a Chemically Induced Aganglionosis Model. Plos One. 11: e0150579. PMID 26943905 DOI: 10.1371/Journal.Pone.0150579  0.372
2016 Matsumoto T, Fujimori K, Andoh-Noda T, Ando T, Kuzumaki N, Toyoshima M, Tada H, Imaizumi K, Ishikawa M, Yamaguchi R, Isoda M, Zhou Z, Sato S, Kobayashi T, Ohtaka M, ... ... Okano H, et al. Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling. Stem Cell Reports. PMID 26905201 DOI: 10.1016/J.Stemcr.2016.01.010  0.412
2016 Ogawa Y, Morikawa S, Okano H, Mabuchi Y, Suzuki S, Yaguchi T, Sato Y, Mukai S, Yaguchi S, Inaba T, Okamoto S, Kawakami Y, Tsubota K, Matsuzaki Y, Shimmura S. MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model. Elife. 5. PMID 26809474 DOI: 10.7554/Elife.09394  0.328
2016 Nishiyama Y, Iwanami A, Kohyama J, Itakura G, Kawabata S, Sugai K, Nishimura S, Kashiwagi R, Yasutake K, Isoda M, Matsumoto M, Nakamura M, Okano H. Safe and efficient method for cryopreservation of human induced pluripotent stem cell-derived neural stem and progenitor cells by a programmed freezer with a magnetic field. Neuroscience Research. PMID 26804710 DOI: 10.1016/J.Neures.2015.11.011  0.406
2016 Yano M, Hayakawa-Yano Y, Okano H. RNA Regulation went wrong in neurodevelopmental disorders: the example of Msi/Elav RNA binding proteins. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 26796049 DOI: 10.1016/J.Ijdevneu.2016.01.002  0.353
2016 Iida T, Iwanami A, Kohyama J, Nagoshi N, Matsumoto M, Okano H, Nakamura M. STMC-09. ASSESSMENT OF TUMORIGENIC POTENTIAL OF HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED NEURAL STEM/PROGENITOR CELLS Neuro-Oncology. 18: vi184-vi184. DOI: 10.1093/Neuonc/Now212.773  0.376
2016 Veraitch O, Mabuchi Y, Matsuzaki Y, Sasaki T, Tsukashima A, Amagai M, Okano H, Ohyama M. Use of human induced pluripotent stem cell-derived CD271+CD90+ mesenchymal stem cells for the generation of hair inductive dermal cells Journal of Dermatological Science. 84: e55. DOI: 10.1016/J.Jdermsci.2016.08.170  0.338
2015 Kawabata S, Takano M, Numasawa-Kuroiwa Y, Itakura G, Kobayashi Y, Nishiyama Y, Sugai K, Nishimura S, Iwai H, Isoda M, Shibata S, Kohyama J, Iwanami A, Toyama Y, Matsumoto M, ... ... Okano H, et al. Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury. Stem Cell Reports. PMID 26724902 DOI: 10.1016/J.Stemcr.2015.11.013  0.381
2015 Grants JM, Ying LT, Yoda A, You CC, Okano H, Sawa H, Taubert S. The Mediator Kinase Module Restrains Epidermal Growth Factor Receptor Signaling and Represses Vulval Cell Fate Specification in Caenorhabditis elegans. Genetics. PMID 26715664 DOI: 10.1534/Genetics.115.180265  0.343
2015 Shimojo D, Onodera K, Doi-Torii Y, Ishihara Y, Hattori C, Miwa Y, Tanaka S, Okada R, Ohyama M, Shoji M, Nakanishi A, Doyu M, Okano H, Okada Y. Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells. Molecular Brain. 8: 79. PMID 26626025 DOI: 10.1186/S13041-015-0172-4  0.353
2015 Imaizumi K, Sone T, Ibata K, Fujimori K, Yuzaki M, Akamatsu W, Okano H. Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes. Stem Cell Reports. PMID 26549851 DOI: 10.1016/J.Stemcr.2015.10.005  0.33
2015 Maekawa M, Iwayama Y, Ohnishi T, Toyoshima M, Shimamoto C, Hisano Y, Toyota T, Balan S, Matsuzaki H, Iwata Y, Takagai S, Yamada K, Ota M, Fukuchi S, Okada Y, ... ... Okano H, et al. Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism. Scientific Reports. 5: 16239. PMID 26548558 DOI: 10.1038/Srep16239  0.356
2015 Lin ZY, Hikabe O, Suzuki S, Hirano T, Siomi H, Sasaki E, Imamura M, Okano H. Sphere-formation culture of testicular germ cells in the common marmoset, a small New World monkey. Primates; Journal of Primatology. PMID 26530217 DOI: 10.1007/S10329-015-0500-4  0.308
2015 Yasui T, Mabuchi Y, Toriumi H, Ebine T, Niibe K, Houlihan DD, Morikawa S, Onizawa K, Kawana H, Akazawa C, Suzuki N, Nakagawa T, Okano H, Matsuzaki Y. Purified Human Dental Pulp Stem Cells Promote Osteogenic Regeneration. Journal of Dental Research. PMID 26494655 DOI: 10.1177/0022034515610748  0.415
2015 Kohro Y, Sakaguchi E, Tashima R, Tozaki-Saitoh H, Okano H, Inoue K, Tsuda M. A new minimally-invasive method for microinjection into the mouse spinal dorsal horn. Scientific Reports. 5: 14306. PMID 26387932 DOI: 10.1038/Srep14306  0.345
2015 Ohtsuka T, Yano M, Okano H. Acute reduction of neuronal RNA binding Elavl2 protein and Gap43 mRNA in mouse hippocampus after kainic acid treatment. Biochemical and Biophysical Research Communications. 466: 46-51. PMID 26325429 DOI: 10.1016/J.Bbrc.2015.08.103  0.361
2015 Masuda H, Maruyama T, Gargett CE, Miyazaki K, Matsuzaki Y, Okano H, Tanaka M. Endometrial Side Population Cells: Potential Adult Stem/Progenitor Cells in Endometrium. Biology of Reproduction. 93: 84. PMID 26316062 DOI: 10.1095/Biolreprod.115.131490  0.396
2015 Sugai K, Nishimura S, Kato-Negishi M, Onoe H, Iwanaga S, Toyama Y, Matsumoto M, Takeuchi S, Okano H, Nakamura M. Neural stem/progenitor cell-laden microfibers promote transplant survival in a mouse transected spinal cord injury model. Journal of Neuroscience Research. PMID 26301451 DOI: 10.1002/Jnr.23636  0.316
2015 Yokota K, Kobayakawa K, Kubota K, Miyawaki A, Okano H, Ohkawa Y, Iwamoto Y, Okada S. Engrafted Neural Stem/Progenitor Cells Promote Functional Recovery through Synapse Reorganization with Spared Host Neurons after Spinal Cord Injury. Stem Cell Reports. 5: 264-77. PMID 26190527 DOI: 10.1016/J.Stemcr.2015.06.004  0.348
2015 Ono M, Kajitani T, Uchida H, Arase T, Oda H, Uchida S, Ota K, Nagashima T, Masuda H, Miyazaki K, Asada H, Hida N, Mabuchi Y, Morikawa S, Ito M, ... ... Okano H, et al. CD34 and CD49f Double-Positive and Lineage Marker-Negative Cells Isolated from Human Myometrium Exhibit Stem Cell-Like Properties Involved in Pregnancy-Induced Uterine Remodeling. Biology of Reproduction. PMID 26108791 DOI: 10.1095/Biolreprod.114.127126  0.341
2015 Ohta E, Nihira T, Uchino A, Imaizumi Y, Okada Y, Akamatsu W, Takahashi K, Hayakawa H, Nagai M, Ohyama M, Ryo M, Ogino M, Murayama S, Takashima A, Nishiyama K, ... ... Okano H, et al. I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway. Human Molecular Genetics. PMID 26056228 DOI: 10.1093/Hmg/Ddv212  0.329
2015 Mabuchi Y, Okano H. Human somatic stem cell-based therapy for cartilage regeneration. Annals of Translational Medicine. 3: S17. PMID 26046062 DOI: 10.3978/J.Issn.2305-5839.2015.02.35  0.37
2015 Iwai H, Shimada H, Nishimura S, Kobayashi Y, Itakura G, Hori K, Hikishima K, Ebise H, Negishi N, Shibata S, Habu S, Toyama Y, Nakamura M, Okano H. Allogeneic Neural Stem/Progenitor Cells Derived From Embryonic Stem Cells Promote Functional Recovery After Transplantation Into Injured Spinal Cord of Nonhuman Primates. Stem Cells Translational Medicine. 4: 708-19. PMID 26019226 DOI: 10.5966/Sctm.2014-0215  0.384
2015 Ishii K, Suzuki N, Mabuchi Y, Ito N, Kikura N, Fukada S, Okano H, Takeda S, Akazawa C. Muscle Satellite Cell Protein Teneurin-4 Regulates Differentiation During Muscle Regeneration. Stem Cells (Dayton, Ohio). 33: 3017-27. PMID 26013034 DOI: 10.1002/Stem.2058  0.326
2015 Andoh-Noda T, Akamatsu W, Miyake K, Matsumoto T, Yamaguchi R, Sanosaka T, Okada Y, Kobayashi T, Ohyama M, Nakashima K, Kurosawa H, Kubota T, Okano H. Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage. Molecular Brain. 8: 31. PMID 26012557 DOI: 10.1186/S13041-015-0121-2  0.452
2015 Izpisua Belmonte JC, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, et al. Brains, genes, and primates. Neuron. 86: 617-31. PMID 25950631 DOI: 10.1016/J.Neuron.2015.03.021  0.347
2015 Takata N, Yoshida K, Komaki Y, Xu M, Sakai Y, Hikishima K, Mimura M, Okano H, Tanaka KF. Optogenetic activation of CA1 pyramidal neurons at the dorsal and ventral hippocampus evokes distinct brain-wide responses revealed by mouse fMRI. Plos One. 10: e0121417. PMID 25793741 DOI: 10.1371/Journal.Pone.0121417  0.302
2015 Kano S, Yuan M, Cardarelli RA, Maegawa G, Higurashi N, Gaval-Cruz M, Wilson AM, Tristan C, Kondo MA, Chen Y, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, ... ... Okano H, et al. Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy. Current Molecular Medicine. 15: 138-45. PMID 25732146 DOI: 10.2174/1566524015666150303110300  0.375
2015 Itakura G, Kobayashi Y, Nishimura S, Iwai H, Takano M, Iwanami A, Toyama Y, Okano H, Nakamura M. Controlling immune rejection is a fail-safe system against potential tumorigenicity after human iPSC-derived neural stem cell transplantation. Plos One. 10: e0116413. PMID 25706286 DOI: 10.1371/Journal.Pone.0116413  0.323
2015 Nori S, Okada Y, Nishimura S, Sasaki T, Itakura G, Kobayashi Y, Renault-Mihara F, Shimizu A, Koya I, Yoshida R, Kudoh J, Koike M, Uchiyama Y, Ikeda E, Toyama Y, ... ... Okano H, et al. Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transition. Stem Cell Reports. 4: 360-73. PMID 25684226 DOI: 10.1016/J.Stemcr.2015.01.006  0.346
2015 Lin ZY, Hirano T, Shibata S, Seki NM, Kitajima R, Sedohara A, Siomi MC, Sasaki E, Siomi H, Imamura M, Okano H. Gene expression ontogeny of spermatogenesis in the marmoset uncovers primate characteristics during testicular development. Developmental Biology. 400: 43-58. PMID 25624265 DOI: 10.1016/J.Ydbio.2015.01.014  0.404
2015 Fujioka M, Okano H, Edge AS. Manipulating cell fate in the cochlea: a feasible therapy for hearing loss. Trends in Neurosciences. 38: 139-44. PMID 25593106 DOI: 10.1016/J.Tins.2014.12.004  0.379
2015 Shibata S, Komaki Y, Seki F, Inouye MO, Nagai T, Okano H. Connectomics: comprehensive approaches for whole-brain mapping. Microscopy (Oxford, England). 64: 57-67. PMID 25527636 DOI: 10.1093/Jmicro/Dfu103  0.308
2015 Hayashi S, Yano M, Igarashi M, Okano HJ, Okano H. Alternative role of HuD splicing variants in neuronal differentiation. Journal of Neuroscience Research. 93: 399-409. PMID 25332105 DOI: 10.1002/Jnr.23496  0.406
2015 Nishikawa R, Hotta R, Shimojima N, Shibata S, Nagoshi N, Nakamura M, Matsuzaki Y, Okano HJ, Kuroda T, Okano H, Morikawa Y. Migration and differentiation of transplanted enteric neural crest-derived cells in murine model of Hirschsprung's disease. Cytotechnology. 67: 661-70. PMID 25230796 DOI: 10.1007/S10616-014-9754-8  0.438
2015 Yano M, Ohtsuka T, Okano H. RNA-binding protein research with transcriptome-wide technologies in neural development. Cell and Tissue Research. 359: 135-44. PMID 25027052 DOI: 10.1007/S00441-014-1923-8  0.301
2015 Ogawa Y, Morikawa S, Okano H, Mabuchi Y, Suzuki S, Yaguchi T, Sato Y, Mukai S, Yaguchi S, Inaba T, Okamoto S, Kawakami Y, Tsubota K, Matsuzaki Y, Shimmura S. Author response: MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model Elife. DOI: 10.7554/Elife.09394.034  0.318
2015 Numasawa-Kuroiwa Y, Okada Y, Shibata S, Kishi N, Akamatsu W, Shoji M, Nakanishi A, Oyama M, Osaka H, Inoue K, Takahashi K, Yamanaka S, Kosaki K, Takahashi T, Okano H. Erratum: Involvement of ER stress in dysmyelination of pelizaeus-merzbacher disease with plp1 missense mutations shown by iPSC-derived oligodendrocytes (Stem Cell Reports (2014) 2 (648-661)) Stem Cell Reports. 4. DOI: 10.1016/J.Stemcr.2014.12.010  0.31
2015 Belmonte JCI, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, et al. Corrigendum to Brains, Genes, and Primates [Neuron 86, 617-631; May 6, 2015] Neuron. 87: 671. DOI: 10.1016/J.Neuron.2015.07.021  0.315
2015 Mizutari K, Fujioka M, Hosoya M, Bramhall N, Okano HJ, Okano H, Edge ASB. Erratum to Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma [Neuron 77, (2013), 58-69] Neuron. 86. DOI: 10.1016/J.Neuron.2015.03.052  0.355
2014 Kuwako K, Nishimoto Y, Kawase S, Okano HJ, Okano H. Cadherin-7 regulates mossy fiber connectivity in the cerebellum. Cell Reports. 9: 311-23. PMID 25284782 DOI: 10.1016/J.Celrep.2014.08.063  0.323
2014 Kondo T, Funayama M, Tsukita K, Hotta A, Yasuda A, Nori S, Kaneko S, Nakamura M, Takahashi R, Okano H, Yamanaka S, Inoue H. Focal transplantation of human iPSC-derived glial-rich neural progenitors improves lifespan of ALS mice. Stem Cell Reports. 3: 242-9. PMID 25254338 DOI: 10.1016/J.Stemcr.2014.05.017  0.345
2014 Okano H. Stem cell research and regenerative medicine in 2014: first year of regenerative medicine in Japan. Stem Cells and Development. 23: 2127-8. PMID 25192239 DOI: 10.1089/Scd.2014.0200  0.31
2014 Matsuzaki Y, Mabuchi Y, Okano H. Leptin receptor makes its mark on MSCs. Cell Stem Cell. 15: 112-4. PMID 25105573 DOI: 10.1016/J.Stem.2014.07.001  0.344
2014 Kawase S, Kuwako K, Imai T, Renault-Mihara F, Yaguchi K, Itohara S, Okano H. Regulatory factor X transcription factors control Musashi1 transcription in mouse neural stem/progenitor cells. Stem Cells and Development. 23: 2250-61. PMID 25058468 DOI: 10.1089/Scd.2014.0219  0.411
2014 Numasawa-Kuroiwa Y, Okada Y, Shibata S, Kishi N, Akamatsu W, Shoji M, Nakanishi A, Oyama M, Osaka H, Inoue K, Takahashi K, Yamanaka S, Kosaki K, Takahashi T, Okano H. Involvement of ER stress in dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 missense mutations shown by iPSC-derived oligodendrocytes. Stem Cell Reports. 2: 648-61. PMID 24936452 DOI: 10.1016/J.Stemcr.2014.03.007  0.305
2014 Yoshida T, Ozawa Y, Suzuki K, Yuki K, Ohyama M, Akamatsu W, Matsuzaki Y, Shimmura S, Mitani K, Tsubota K, Okano H. The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa. Molecular Brain. 7: 45. PMID 24935155 DOI: 10.1186/1756-6606-7-45  0.342
2014 Sakuraba M, Murata J, Teruyama R, Kamiya K, Yamaguchi J, Okano H, Uchiyama Y, Ikeda K. Spatiotemporal expression of TRPM4 in the mouse cochlea. Journal of Neuroscience Research. 92: 1409-18. PMID 24840118 DOI: 10.1002/Jnr.23410  0.378
2014 Itakura G, Kobayashi Y, Nishimura S, Iwai H, Takano M, Iwanami A, Toyama Y, Okano H, Nakamura M. Control of the survival and growth of human glioblastoma grafted into the spinal cord of mice by taking advantage of immunorejection. Cell Transplantation. PMID 24818989 DOI: 10.3727/096368914X681711  0.324
2014 Bamba Y, Shofuda T, Kanematsu D, Nonaka M, Yamasaki M, Okano H, Kanemura Y. Differentiation, polarization, and migration of human induced pluripotent stem cell-derived neural progenitor cells co-cultured with a human glial cell line with radial glial-like characteristics. Biochemical and Biophysical Research Communications. 447: 683-8. PMID 24755070 DOI: 10.1016/J.Bbrc.2014.04.070  0.398
2014 Sakurai M, Kunimoto H, Watanabe N, Fukuchi Y, Yuasa S, Yamazaki S, Nishimura T, Sadahira K, Fukuda K, Okano H, Nakauchi H, Morita Y, Matsumura I, Kudo K, Ito E, et al. Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients. Leukemia. 28: 2344-54. PMID 24732596 DOI: 10.1038/Leu.2014.136  0.355
2014 Zhou Z, Kohda K, Ibata K, Kohyama J, Akamatsu W, Yuzaki M, Okano HJ, Sasaki E, Okano H. Reprogramming non-human primate somatic cells into functional neuronal cells by defined factors. Molecular Brain. 7: 24. PMID 24694048 DOI: 10.1186/1756-6606-7-24  0.406
2014 Okano H, Yamanaka S. iPS cell technologies: significance and applications to CNS regeneration and disease. Molecular Brain. 7: 22. PMID 24685317 DOI: 10.1186/1756-6606-7-22  0.336
2014 Itaba N, Wairagu PM, Aramaki N, Yasui T, Matsumi Y, Kono Y, Phan AN, Otsu M, Kunisada T, Nakamura Y, Okano H, Jeong Y, Shiota G. Nuclear receptor gene alteration in human induced pluripotent stem cells with hepatic differentiation propensity. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 44: E408-19. PMID 24636009 DOI: 10.1111/Hepr.12329  0.55
2014 DeBoer EM, Azevedo R, Vega TA, Brodkin J, Akamatsu W, Okano H, Wagner GC, Rasin MR. Prenatal deletion of the RNA-binding protein HuD disrupts postnatal cortical circuit maturation and behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3674-86. PMID 24599466 DOI: 10.1523/Jneurosci.3703-13.2014  0.341
2014 Bae BI, Tietjen I, Atabay KD, Evrony GD, Johnson MB, Asare E, Wang PP, Murayama AY, Im K, Lisgo SN, Overman L, Šestan N, Chang BS, Barkovich AJ, Grant PE, ... ... Okano H, et al. Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning. Science (New York, N.Y.). 343: 764-8. PMID 24531968 DOI: 10.1126/Science.1244392  0.36
2014 Yamaguchi S, Marumoto T, Nii T, Kawano H, Liao J, Nagai Y, Okada M, Takahashi A, Inoue H, Sasaki E, Fujii H, Okano S, Ebise H, Sato T, Suyama M, ... Okano H, et al. Characterization of common marmoset dysgerminoma-like tumor induced by the lentiviral expression of reprogramming factors. Cancer Science. 105: 402-8. PMID 24521492 DOI: 10.1111/Cas.12367  0.328
2014 Imaizumi Y, Okano H. Modeling human neurological disorders with induced pluripotent stem cells. Journal of Neurochemistry. 129: 388-99. PMID 24286589 DOI: 10.1111/Jnc.12625  0.372
2014 Kim C, Kim W, Lee H, Ji E, Choe YJ, Martindale JL, Akamatsu W, Okano H, Kim HS, Nam SW, Gorospe M, Lee EK. The RNA-binding protein HuD regulates autophagosome formation in pancreatic β cells by promoting autophagy-related gene 5 expression. The Journal of Biological Chemistry. 289: 112-21. PMID 24275661 DOI: 10.1074/Jbc.M113.474700  0.35
2014 Tomioka T, Shimazaki T, Yamauchi T, Oki T, Ohgoh M, Okano H. LIM homeobox 8 (Lhx8) is a key regulator of the cholinergic neuronal function via a tropomyosin receptor kinase A (TrkA)-mediated positive feedback loop. The Journal of Biological Chemistry. 289: 1000-10. PMID 24265310 DOI: 10.1074/Jbc.M113.494385  0.351
2014 Ohyama M, Okano H. Promise of human induced pluripotent stem cells in skin regeneration and investigation. The Journal of Investigative Dermatology. 134: 605-9. PMID 24132166 DOI: 10.1038/Jid.2013.376  0.304
2014 Iwai H, Nori S, Nishimura S, Yasuda A, Takano M, Tsuji O, Fujiyoshi K, Toyama Y, Okano H, Nakamura M. Transplantation of neural stem/progenitor cells at different locations in mice with spinal cord injury. Cell Transplantation. 23: 1451-64. PMID 23998989 DOI: 10.3727/096368913X670967  0.333
2014 Imamura M, Hikabe O, Lin ZY, Okano H. Generation of germ cells in vitro in the era of induced pluripotent stem cells. Molecular Reproduction and Development. 81: 2-19. PMID 23996404 DOI: 10.1002/Mrd.22259  0.415
2014 Morizane R, Monkawa T, Fujii S, Yamaguchi S, Homma K, Matsuzaki Y, Okano H, Itoh H. Kidney specific protein-positive cells derived from embryonic stem cells reproduce tubular structures in vitro and differentiate into renal tubular cells. Plos One. 8: e64843. PMID 23755150 DOI: 10.1371/Journal.Pone.0064843  0.391
2014 Matsui T, Akamatsu W, Nakamura M, Okano H. Regeneration of the damaged central nervous system through reprogramming technology: basic concepts and potential application for cell replacement therapy. Experimental Neurology. 260: 12-8. PMID 23036600 DOI: 10.1016/J.Expneurol.2012.09.016  0.43
2014 Fukuhara S, Suzuki H, Masaoka T, Matsuzaki J, Tsugawa H, Okada S, Mori H, Nishimura S, Kawase S, Nakamura M, Okano H, Kanai T. 66 Neural Stem Cell Transplantation Restored the Delayed Gastric Emptying in Apolipoprotein E-Knockout Mice Gastroenterology. 146: S-19. DOI: 10.1016/S0016-5085(14)60066-4  0.314
2013 Imamura M, Lin ZY, Okano H. Cell-intrinsic reprogramming capability: gain or loss of pluripotency in germ cells. Reproductive Medicine and Biology. 12: 1-14. PMID 29699125 DOI: 10.1007/S12522-012-0131-Z  0.423
2013 Shofuda T, Kanematsu D, Fukusumi H, Yamamoto A, Bamba Y, Yoshitatsu S, Suemizu H, Nakamura M, Sugimoto Y, Furue MK, Kohara A, Akamatsu W, Okada Y, Okano H, Yamasaki M, et al. Human Decidua-Derived Mesenchymal Cells Are a Promising Source for the Generation and Cell Banking of Human Induced Pluripotent Stem Cells. Cell Medicine. 4: 125-47. PMID 26858858 DOI: 10.3727/215517912X658918  0.412
2013 Nakamura M, Toyama Y, Okano H. [Current status and perspective on regenerative medicine for spinal cord injury using iPS cell]. Rinshå Shinkeigaku = Clinical Neurology. 53: 1013-5. PMID 24291863 DOI: 10.5692/Clinicalneurol.53.1013  0.372
2013 Horiuchi Y, Kano S, Ishizuka K, Cascella NG, Ishii S, Talbot CC, Jaffe AE, Okano H, Pevsner J, Colantuoni C, Sawa A. Olfactory cells via nasal biopsy reflect the developing brain in gene expression profiles: utility and limitation of the surrogate tissues in research for brain disorders. Neuroscience Research. 77: 247-50. PMID 24120685 DOI: 10.1016/J.Neures.2013.09.010  0.412
2013 Ohta S, Misawa A, Lefebvre V, Okano H, Kawakami Y, Toda M. Sox6 up-regulation by macrophage migration inhibitory factor promotes survival and maintenance of mouse neural stem/progenitor cells. Plos One. 8: e74315. PMID 24066135 DOI: 10.1371/Journal.Pone.0074315  0.43
2013 Mabuchi Y, Morikawa S, Harada S, Niibe K, Suzuki S, Renault-Mihara F, Houlihan DD, Akazawa C, Okano H, Matsuzaki Y. LNGFR(+)THY-1(+)VCAM-1(hi+) cells reveal functionally distinct subpopulations in mesenchymal stem cells. Stem Cell Reports. 1: 152-65. PMID 24052950 DOI: 10.1016/J.Stemcr.2013.06.001  0.397
2013 Sato H, Shibata M, Shimizu T, Shibata S, Toriumi H, Ebine T, Kuroi T, Iwashita T, Funakubo M, Kayama Y, Akazawa C, Wajima K, Nakagawa T, Okano H, Suzuki N. Differential cellular localization of antioxidant enzymes in the trigeminal ganglion. Neuroscience. 248: 345-58. PMID 23774632 DOI: 10.1016/J.Neuroscience.2013.06.010  0.344
2013 Mabuchi Y, Houlihan DD, Akazawa C, Okano H, Matsuzaki Y. Prospective isolation of murine and human bone marrow mesenchymal stem cells based on surface markers. Stem Cells International. 2013: 507301. PMID 23766770 DOI: 10.1155/2013/507301  0.355
2013 Natsume A, Ito M, Katsushima K, Ohka F, Hatanaka A, Shinjo K, Sato S, Takahashi S, Ishikawa Y, Takeuchi I, Shimogawa H, Uesugi M, Okano H, Kim SU, Wakabayashi T, et al. Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma. Cancer Research. 73: 4559-70. PMID 23720055 DOI: 10.1158/0008-5472.Can-13-0109  0.365
2013 Lin CH, Lee HT, Lee SD, Lee W, Cho CW, Lin SZ, Wang HJ, Okano H, Su CY, Yu YL, Hsu CY, Shyu WC. Role of HIF-1α-activated Epac1 on HSC-mediated neuroplasticity in stroke model. Neurobiology of Disease. 58: 76-91. PMID 23702312 DOI: 10.1016/J.Nbd.2013.05.006  0.347
2013 Higurashi N, Uchida T, Lossin C, Misumi Y, Okada Y, Akamatsu W, Imaizumi Y, Zhang B, Nabeshima K, Mori MX, Katsurabayashi S, Shirasaka Y, Okano H, Hirose S. A human Dravet syndrome model from patient induced pluripotent stem cells. Molecular Brain. 6: 19. PMID 23639079 DOI: 10.1186/1756-6606-6-19  0.334
2013 Ohta S, Imaizumi Y, Akamatsu W, Okano H, Kawakami Y. Generation of human melanocytes from induced pluripotent stem cells. Methods in Molecular Biology (Clifton, N.J.). 989: 193-215. PMID 23483397 DOI: 10.1007/978-1-62703-330-5_16  0.389
2013 Nitta M, Imamura M, Inoue Y, Kunitomo Y, Lin ZY, Ogawa T, Yogo K, Ishida-Kitagawa N, Fukunaga N, Okano H, Sato E, Takeya T, Miyoshi J. Aberrant gene expression and sexually incompatible genomic imprinting in oocytes derived from XY mouse embryonic stem cells in vitro. Plos One. 8: e58555. PMID 23472205 DOI: 10.1371/Journal.Pone.0058555  0.402
2013 Kanda H, Nguyen A, Chen L, Okano H, Hariharan IK. The Drosophila ortholog of MLL3 and MLL4, trithorax related, functions as a negative regulator of tissue growth. Molecular and Cellular Biology. 33: 1702-10. PMID 23459941 DOI: 10.1128/Mcb.01585-12  0.35
2013 Okano H, Nakamura M, Yoshida K, Okada Y, Tsuji O, Nori S, Ikeda E, Yamanaka S, Miura K. Steps toward safe cell therapy using induced pluripotent stem cells. Circulation Research. 112: 523-33. PMID 23371901 DOI: 10.1161/Circresaha.111.256149  0.382
2013 Nihei Y, Ito D, Okada Y, Akamatsu W, Yagi T, Yoshizaki T, Okano H, Suzuki N. Enhanced aggregation of androgen receptor in induced pluripotent stem cell-derived neurons from spinal and bulbar muscular atrophy. The Journal of Biological Chemistry. 288: 8043-52. PMID 23364790 DOI: 10.1074/Jbc.M112.408211  0.373
2013 Imai S, Ikegami D, Yamashita A, Shimizu T, Narita M, Niikura K, Furuya M, Kobayashi Y, Miyashita K, Okutsu D, Kato A, Nakamura A, Araki A, Omi K, Nakamura M, ... ... Okano H, et al. Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain. Brain : a Journal of Neurology. 136: 828-43. PMID 23364351 DOI: 10.1093/Brain/Aws330  0.302
2013 Veraitch O, Kobayashi T, Imaizumi Y, Akamatsu W, Sasaki T, Yamanaka S, Amagai M, Okano H, Ohyama M. Human induced pluripotent stem cell-derived ectodermal precursor cells contribute to hair follicle morphogenesis in vivo. The Journal of Investigative Dermatology. 133: 1479-88. PMID 23321923 DOI: 10.1038/Jid.2013.7  0.405
2013 Mizutari K, Fujioka M, Hosoya M, Bramhall N, Okano HJ, Okano H, Edge AS. Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma. Neuron. 77: 58-69. PMID 23312516 DOI: 10.1016/J.Neuron.2012.10.032  0.391
2013 Nakamura M, Okano H. Cell transplantation therapies for spinal cord injury focusing on induced pluripotent stem cells. Cell Research. 23: 70-80. PMID 23229514 DOI: 10.1038/Cr.2012.171  0.379
2013 Hirata A, Utikal J, Yamashita S, Aoki H, Watanabe A, Yamamoto T, Okano H, Bardeesy N, Kunisada T, Ushijima T, Hara A, Jaenisch R, Hochedlinger K, Yamada Y. Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium. Development (Cambridge, England). 140: 66-75. PMID 23222438 DOI: 10.1242/Jcs.130047  0.388
2013 Hatou S, Yoshida S, Higa K, Miyashita H, Inagaki E, Okano H, Tsubota K, Shimmura S. Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/β-catenin signaling. Stem Cells and Development. 22: 828-39. PMID 22974347 DOI: 10.1089/Scd.2012.0286  0.394
2013 Veraitch OK, Kobayashi T, Imaizumi Y, Akamatsu W, Amagai M, Okano H, Ohyama M. Human induced pluripotent stem cell line with hair forming capacity is ectodermal/epithelial lineage-prone and in WNT-activated state Journal of Dermatological Science. 69: e65. DOI: 10.1016/J.Jdermsci.2012.11.500  0.338
2013 Nishimoto Y, Okano HJ, Imai T, Poole AJ, Suzuki N, Keirstead HS, Okano H. Cellular toxicity induced by the 26-kDa fragment and amyotrophic lateral sclerosis-associated mutant forms of TAR DNA-binding protein 43 in human embryonic stem cell-derived motor neurons Neurology and Clinical Neuroscience. 1: 24-31. DOI: 10.1002/Ncn3.2  0.336
2012 Kobayashi Y, Okada Y, Itakura G, Iwai H, Nishimura S, Yasuda A, Nori S, Hikishima K, Konomi T, Fujiyoshi K, Tsuji O, Toyama Y, Yamanaka S, Nakamura M, Okano H. Pre-evaluated safe human iPSC-derived neural stem cells promote functional recovery after spinal cord injury in common marmoset without tumorigenicity. Plos One. 7: e52787. PMID 23300777 DOI: 10.1371/Journal.Pone.0052787  0.351
2012 Sakai D, Nakamura Y, Nakai T, Mishima T, Kato S, Grad S, Alini M, Risbud MV, Chan D, Cheah KS, Yamamura K, Masuda K, Okano H, Ando K, Mochida J. Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc. Nature Communications. 3: 1264. PMID 23232394 DOI: 10.1038/Ncomms2226  0.337
2012 Okano H. [Regeneration of the damaged CNS using human iPSCs-derived neural progenitor cells]. Rinshå Shinkeigaku = Clinical Neurology. 52: 1147. PMID 23196544 DOI: 10.5692/Clinicalneurol.52.1147  0.383
2012 Shimada H, Okada Y, Ibata K, Ebise H, Ota S, Tomioka I, Nomura T, Maeda T, Kohda K, Yuzaki M, Sasaki E, Nakamura M, Okano H. Efficient derivation of multipotent neural stem/progenitor cells from non-human primate embryonic stem cells. Plos One. 7: e49469. PMID 23166679 DOI: 10.1371/Journal.Pone.0049469  0.419
2012 Houlihan DD, Mabuchi Y, Morikawa S, Niibe K, Araki D, Suzuki S, Okano H, Matsuzaki Y. Isolation of mouse mesenchymal stem cells on the basis of expression of Sca-1 and PDGFR-α. Nature Protocols. 7: 2103-11. PMID 23154782 DOI: 10.1038/Nprot.2012.125  0.357
2012 Kuzumaki N, Suzuki A, Narita M, Hosoya T, Nagasawa A, Imai S, Yamamizu K, Morita H, Suzuki T, Okada Y, Okano HJ, Yamashita JK, Okano H, Narita M. Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer. Plos One. 7: e44368. PMID 23144692 DOI: 10.1371/Journal.Pone.0044368  0.333
2012 Kumamaru H, Ohkawa Y, Saiwai H, Yamada H, Kubota K, Kobayakawa K, Akashi K, Okano H, Iwamoto Y, Okada S. Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells. Nature Communications. 3: 1140. PMID 23072808 DOI: 10.1038/Ncomms2132  0.373
2012 Imaizumi Y, Okada Y, Akamatsu W, Koike M, Kuzumaki N, Hayakawa H, Nihira T, Kobayashi T, Ohyama M, Sato S, Takanashi M, Funayama M, Hirayama A, Soga T, Hishiki T, ... ... Okano H, et al. Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Molecular Brain. 5: 35. PMID 23039195 DOI: 10.1186/1756-6606-5-35  0.333
2012 Namiki J, Suzuki S, Masuda T, Ishihama Y, Okano H. Nestin protein is phosphorylated in adult neural stem/progenitor cells and not endothelial progenitor cells. Stem Cells International. 2012: 430138. PMID 23028390 DOI: 10.1155/2012/430138  0.408
2012 Ince-Dunn G, Okano HJ, Jensen KB, Park WY, Zhong R, Ule J, Mele A, Fak JJ, Yang C, Zhang C, Yoo J, Herre M, Okano H, Noebels JL, Darnell RB. Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron. 75: 1067-80. PMID 22998874 DOI: 10.1016/J.Neuron.2012.07.009  0.342
2012 Matsuda S, Kuwako K, Okano HJ, Tsutsumi S, Aburatani H, Saga Y, Matsuzaki Y, Akaike A, Sugimoto H, Okano H. Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 12543-57. PMID 22956844 DOI: 10.1523/Jneurosci.5803-11.2012  0.407
2012 Ito D, Okano H, Suzuki N. Accelerating progress in induced pluripotent stem cell research for neurological diseases. Annals of Neurology. 72: 167-74. PMID 22926850 DOI: 10.1002/Ana.23596  0.348
2012 Imamura M, Okuno H, Tomioka I, Kawamura Y, Lin ZY, Nakajima R, Akamatsu W, Okano HJ, Matsuzaki Y, Sasaki E, Okano H. Derivation of induced pluripotent stem cells by retroviral gene transduction in mammalian species. Methods in Molecular Biology (Clifton, N.J.). 925: 21-48. PMID 22907488 DOI: 10.1007/978-1-62703-011-3_2  0.395
2012 Yagi T, Kosakai A, Ito D, Okada Y, Akamatsu W, Nihei Y, Nabetani A, Ishikawa F, Arai Y, Hirose N, Okano H, Suzuki N. Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research. Plos One. 7: e41572. PMID 22848530 DOI: 10.1371/Journal.Pone.0041572  0.353
2012 Mukai A, Yamamoto-Hino M, Komada M, Okano H, Goto S. Balanced ubiquitination determines cellular responsiveness to extracellular stimuli. Cellular and Molecular Life Sciences : Cmls. PMID 22825661 DOI: 10.1007/S00018-012-1084-4  0.33
2012 Suyama S, Sunabori T, Kanki H, Sawamoto K, Gachet C, Koizumi S, Okano H. Purinergic signaling promotes proliferation of adult mouse subventricular zone cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9238-47. PMID 22764232 DOI: 10.1523/Jneurosci.4001-11.2012  0.735
2012 Mochizuki S, Soejima K, Shimoda M, Abe H, Sasaki A, Okano HJ, Okano H, Okada Y. Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor. Journal of the National Cancer Institute. 104: 906-22. PMID 22636800 DOI: 10.1093/Jnci/Djs232  0.316
2012 Hirota Y, Sawada M, Kida YS, Huang SH, Yamada O, Sakaguchi M, Ogura T, Okano H, Sawamoto K. Roles of planar cell polarity signaling in maturation of neuronal precursor cells in the postnatal mouse olfactory bulb. Stem Cells (Dayton, Ohio). 30: 1726-33. PMID 22628050 DOI: 10.1002/Stem.1137  0.777
2012 Seko Y, Azuma N, Kaneda M, Nakatani K, Miyagawa Y, Noshiro Y, Kurokawa R, Okano H, Umezawa A. Derivation of human differential photoreceptor-like cells from the iris by defined combinations of CRX, RX and NEUROD. Plos One. 7: e35611. PMID 22558175 DOI: 10.1371/Journal.Pone.0035611  0.406
2012 Nakamura M, Tsuji O, Nori S, Toyama Y, Okano H. Cell transplantation for spinal cord injury focusing on iPSCs. Expert Opinion On Biological Therapy. 12: 811-21. PMID 22519931 DOI: 10.1517/14712598.2012.681774  0.372
2012 Mashiko H, Yoshida AC, Kikuchi SS, Niimi K, Takahashi E, Aruga J, Okano H, Shimogori T. Comparative anatomy of marmoset and mouse cortex from genomic expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5039-53. PMID 22496550 DOI: 10.1523/Jneurosci.4788-11.2012  0.329
2012 Sakaguchi M, Okano H. Neural stem cells, adult neurogenesis, and galectin-1: from bench to bedside. Developmental Neurobiology. 72: 1059-67. PMID 22488739 DOI: 10.1002/Dneu.22023  0.573
2012 Matsumoto K, Yokoo T, Matsunari H, Iwai S, Yokote S, Teratani T, Gheisari Y, Tsuji O, Okano H, Utsunomiya Y, Hosoya T, Okano HJ, Nagashima H, Kobayashi E. Xenotransplanted embryonic kidney provides a niche for endogenous mesenchymal stem cell differentiation into erythropoietin-producing tissue. Stem Cells (Dayton, Ohio). 30: 1228-35. PMID 22488594 DOI: 10.1002/Stem.1101  0.419
2012 Matsui T, Takano M, Yoshida K, Ono S, Fujisaki C, Matsuzaki Y, Toyama Y, Nakamura M, Okano H, Akamatsu W. Neural stem cells directly differentiated from partially reprogrammed fibroblasts rapidly acquire gliogenic competency. Stem Cells (Dayton, Ohio). 30: 1109-19. PMID 22467474 DOI: 10.1002/Stem.1091  0.441
2012 Ohta S, Misawa A, Fukaya R, Inoue S, Kanemura Y, Okano H, Kawakami Y, Toda M. Macrophage migration inhibitory factor (MIF) promotes cell survival and proliferation of neural stem/progenitor cells. Journal of Cell Science. 125: 3210-20. PMID 22454509 DOI: 10.1242/Dev.088658  0.413
2012 Shibata S, Umei M, Kawahara H, Yano M, Makino S, Okano H. Characterization of the RNA-binding protein Musashi1 in zebrafish. Brain Research. 1462: 162-73. PMID 22429745 DOI: 10.1016/J.Brainres.2012.01.068  0.416
2012 Muto J, Imai T, Ogawa D, Nishimoto Y, Okada Y, Mabuchi Y, Kawase T, Iwanami A, Mischel PS, Saya H, Yoshida K, Matsuzaki Y, Okano H. RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways. Plos One. 7: e33431. PMID 22428049 DOI: 10.1371/Journal.Pone.0033431  0.409
2012 Yano H, Yamamoto-Hino M, Awano W, Aoki-Kinoshita KF, Tsuda-Sakurai K, Okano H, Goto S. Identification of proteasome components required for apical localization of Chaoptin using functional genomics. Journal of Neurogenetics. 26: 53-63. PMID 22417167 DOI: 10.3109/01677063.2012.661497  0.3
2012 Murata J, Ikeda K, Okano H. Notch signaling and the developing inner ear. Advances in Experimental Medicine and Biology. 727: 161-73. PMID 22399346 DOI: 10.1007/978-1-4614-0899-4_12  0.382
2012 Lin ZY, Imamura M, Sano C, Nakajima R, Suzuki T, Yamadera R, Takehara Y, Okano HJ, Sasaki E, Okano H. Molecular signatures to define spermatogenic cells in common marmoset (Callithrix jacchus). Reproduction (Cambridge, England). 143: 597-609. PMID 22323619 DOI: 10.1530/Rep-11-0215  0.408
2012 Kelava I, Reillo I, Murayama AY, Kalinka AT, Stenzel D, Tomancak P, Matsuzaki F, Lebrand C, Sasaki E, Schwamborn JC, Okano H, Huttner WB, Borrell V. Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus. Cerebral Cortex (New York, N.Y. : 1991). 22: 469-81. PMID 22114084 DOI: 10.1093/Cercor/Bhr301  0.412
2012 Mabuchi Y, Houlihan DD, Okano H, Matsuzaki Y. Discovering the true identity and function of mesenchymal stem cells Inflammation and Regeneration. 32: 146-151. DOI: 10.2492/Inflammregen.32.146  0.352
2012 Yaguchi S, Shimmura S, Inaba T, Matsuzaki Y, Okamoto S, Kawakami Y, Ogawa Y, Morikawa S, Okano H, Mabuchi Y, Suzuki S, Tsubota K, Yaguchi T. Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation Nature Precedings. 7: 1-1. DOI: 10.1038/Npre.2012.6843.1  0.307
2011 Okada Y, Okano H. [Evaluation of human iPS cells by neural differentiation and tumorigenicity]. Rinshå Shinkeigaku = Clinical Neurology. 51: 1079-80. PMID 22277484 DOI: 10.1016/J.Neures.2011.07.1441  0.365
2011 Yoshida S, Yasuda M, Miyashita H, Ogawa Y, Yoshida T, Matsuzaki Y, Tsubota K, Okano H, Shimmura S. Generation of stratified squamous epithelial progenitor cells from mouse induced pluripotent stem cells. Plos One. 6: e28856. PMID 22174914 DOI: 10.1371/Journal.Pone.0028856  0.387
2011 Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H. Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16872-83. PMID 22090513 DOI: 10.1523/Jneurosci.1111-11.2011  0.348
2011 Kanda H, Igaki T, Okano H, Miura M. Conserved metabolic energy production pathways govern Eiger/TNF-induced nonapoptotic cell death. Proceedings of the National Academy of Sciences of the United States of America. 108: 18977-82. PMID 22065747 DOI: 10.1073/Pnas.1103242108  0.331
2011 Yasuda A, Tsuji O, Shibata S, Nori S, Takano M, Kobayashi Y, Takahashi Y, Fujiyoshi K, Hara CM, Miyawaki A, Okano HJ, Toyama Y, Nakamura M, Okano H. Significance of remyelination by neural stem/progenitor cells transplanted into the injured spinal cord. Stem Cells (Dayton, Ohio). 29: 1983-94. PMID 22028197 DOI: 10.1002/Stem.767  0.346
2011 Yamane J, Ishibashi S, Sakaguchi M, Kuroiwa T, Kanemura Y, Nakamura M, Miyoshi H, Sawamoto K, Toyama Y, Mizusawa H, Okano H. Transplantation of human neural stem/progenitor cells overexpressing galectin-1 improves functional recovery from focal brain ischemia in the Mongolian gerbil. Molecular Brain. 4: 35. PMID 21951913 DOI: 10.1186/1756-6606-4-35  0.728
2011 Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, Fujiyoshi K, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Yamanaka S, Nakamura M, Okano H. Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 16825-30. PMID 21949375 DOI: 10.1073/Pnas.1108077108  0.409
2011 Katoh H, Shibata S, Fukuda K, Sato M, Satoh E, Nagoshi N, Minematsu T, Matsuzaki Y, Akazawa C, Toyama Y, Nakamura M, Okano H. The dual origin of the peripheral olfactory system: placode and neural crest. Molecular Brain. 4: 34. PMID 21943152 DOI: 10.1186/1756-6606-4-34  0.385
2011 Okano H. Strategic approaches to regeneration of a damaged central nervous system. Cornea. 30: S15-8. PMID 21912223 DOI: 10.1097/Ico.0B013E3182281879  0.381
2011 Tsuji O, Miura K, Fujiyoshi K, Momoshima S, Nakamura M, Okano H. Cell therapy for spinal cord injury by neural stem/progenitor cells derived from iPS/ES cells. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 8: 668-76. PMID 21909829 DOI: 10.1007/S13311-011-0063-Z  0.391
2011 Yagi T, Ito D, Okada Y, Akamatsu W, Nihei Y, Yoshizaki T, Yamanaka S, Okano H, Suzuki N. Modeling familial Alzheimer's disease with induced pluripotent stem cells. Human Molecular Genetics. 20: 4530-9. PMID 21900357 DOI: 10.1093/Hmg/Ddr394  0.342
2011 Renault-Mihara F, Katoh H, Ikegami T, Iwanami A, Mukaino M, Yasuda A, Nori S, Mabuchi Y, Tada H, Shibata S, Saito K, Matsushita M, Kaibuchi K, Okada S, Toyama Y, ... ... Okano H, et al. Beneficial compaction of spinal cord lesion by migrating astrocytes through glycogen synthase kinase-3 inhibition. Embo Molecular Medicine. 3: 682-96. PMID 21898827 DOI: 10.1016/J.Neures.2011.07.248  0.311
2011 Sakaguchi M, Arruda-Carvalho M, Kang NH, Imaizumi Y, Poirier F, Okano H, Frankland PW. Impaired spatial and contextual memory formation in galectin-1 deficient mice. Molecular Brain. 4: 33. PMID 21884595 DOI: 10.1186/1756-6606-4-33  0.654
2011 Takagi T, Ishii K, Shibata S, Yasuda A, Sato M, Nagoshi N, Saito H, Okano HJ, Toyama Y, Okano H, Nakamura M. Schwann-spheres derived from injured peripheral nerves in adult mice--their in vitro characterization and therapeutic potential. Plos One. 6: e21497. PMID 21720551 DOI: 10.1371/Journal.Pone.0021497  0.395
2011 Nakamura M, Tsuji O, Bregman BS, Toyama Y, Okano H. Mimicking the neurotrophic factor profile of embryonic spinal cord controls the differentiation potential of spinal progenitors into neuronal cells. Plos One. 6: e20717. PMID 21698095 DOI: 10.1371/Journal.Pone.0020717  0.403
2011 Tabuse M, Ohta S, Ohashi Y, Fukaya R, Misawa A, Yoshida K, Kawase T, Saya H, Thirant C, Chneiweiss H, Matsuzaki Y, Okano H, Kawakami Y, Toda M. Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells. Molecular Cancer. 10: 60. PMID 21600039 DOI: 10.1186/1476-4598-10-60  0.437
2011 Fujioka M, Tokano H, Fujioka KS, Okano H, Edge AS. Generating mouse models of degenerative diseases using Cre/lox-mediated in vivo mosaic cell ablation. The Journal of Clinical Investigation. 121: 2462-9. PMID 21576819 DOI: 10.1172/Jci45081  0.366
2011 Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Okuno Y, Nakamura-Ishizu A, Sano K, Murakami M, Ema M, Omatsu Y, Takahashi S, Nagasawa T, Shibuya M, Okano H, et al. Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero. The Journal of Experimental Medicine. 208: 949-60. PMID 21536740 DOI: 10.1084/Jem.20102187  0.328
2011 Kawase S, Imai T, Miyauchi-Hara C, Yaguchi K, Nishimoto Y, Fukami S, Matsuzaki Y, Miyawaki A, Itohara S, Okano H. Identification of a novel intronic enhancer responsible for the transcriptional regulation of musashi1 in neural stem/progenitor cells. Molecular Brain. 4: 14. PMID 21486496 DOI: 10.1186/1756-6606-4-14  0.459
2011 Ishizuka K, Kamiya A, Oh EC, Kanki H, Seshadri S, Robinson JF, Murdoch H, Dunlop AJ, Kubo K, Furukori K, Huang B, Zeledon M, Hayashi-Takagi A, Okano H, Nakajima K, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature. 473: 92-6. PMID 21471969 DOI: 10.1038/Nature09859  0.387
2011 Cucchiaroni ML, Freestone PS, Berretta N, Viscomi MT, Bisicchia E, Okano H, Molinari M, Bernardi G, Lipski J, Mercuri NB, Guatteo E. Properties of dopaminergic neurons in organotypic mesencephalic-striatal co-cultures--evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by α-1 adrenergic receptors. The European Journal of Neuroscience. 33: 1622-36. PMID 21453288 DOI: 10.1111/J.1460-9568.2011.07659.X  0.306
2011 Niibe K, Kawamura Y, Araki D, Morikawa S, Miura K, Suzuki S, Shimmura S, Sunabori T, Mabuchi Y, Nagai Y, Nakagawa T, Okano H, Matsuzaki Y. Purified mesenchymal stem cells are an efficient source for iPS cell induction. Plos One. 6: e17610. PMID 21412425 DOI: 10.1371/Journal.Pone.0017610  0.409
2011 Kawahara H, Okada Y, Imai T, Iwanami A, Mischel PS, Okano H. Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiation. The Journal of Biological Chemistry. 286: 16121-30. PMID 21378162 DOI: 10.1074/Jbc.M110.199166  0.358
2011 Nagoshi N, Shibata S, Hamanoue M, Mabuchi Y, Matsuzaki Y, Toyama Y, Nakamura M, Okano H. Schwann cell plasticity after spinal cord injury shown by neural crest lineage tracing. Glia. 59: 771-84. PMID 21351159 DOI: 10.1002/Glia.21150  0.396
2011 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI. Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells. The Journal of Biological Chemistry. 286: 13754-64. PMID 21349854 DOI: 10.1074/Jbc.M110.194936  0.433
2011 Hosoya M, Fujioka M, Matsuda S, Ohba H, Shibata S, Nakagawa F, Watabe T, Wakabayashi K, Saga Y, Ogawa K, Okano HJ, Okano H. Expression and function of Sox21 during mouse cochlea development. Neurochemical Research. 36: 1261-9. PMID 21287267 DOI: 10.1007/S11064-011-0416-3  0.432
2011 Imaizumi Y, Sakaguchi M, Morishita T, Ito M, Poirier F, Sawamoto K, Okano H. Galectin-1 is expressed in early-type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus. Molecular Brain. 4: 7. PMID 21269521 DOI: 10.1016/J.Neures.2010.07.1619  0.776
2011 Ohta S, Imaizumi Y, Okada Y, Akamatsu W, Kuwahara R, Ohyama M, Amagai M, Matsuzaki Y, Yamanaka S, Okano H, Kawakami Y. Generation of human melanocytes from induced pluripotent stem cells. Plos One. 6: e16182. PMID 21249204 DOI: 10.1371/Journal.Pone.0016182  0.41
2011 Sawamoto K, Hirota Y, Alfaro-Cervello C, Soriano-Navarro M, He X, Hayakawa-Yano Y, Yamada M, Hikishima K, Tabata H, Iwanami A, Nakajima K, Toyama Y, Itoh T, Alvarez-Buylla A, Garcia-Verdugo JM, ... Okano H, et al. Cellular composition and organization of the subventricular zone and rostral migratory stream in the adult and neonatal common marmoset brain. The Journal of Comparative Neurology. 519: 690-713. PMID 21246550 DOI: 10.1002/Cne.22543  0.71
2011 Tamura Y, Matsumura K, Sano M, Tabata H, Kimura K, Ieda M, Arai T, Ohno Y, Kanazawa H, Yuasa S, Kaneda R, Makino S, Nakajima K, Okano H, Fukuda K. Neural crest-derived stem cells migrate and differentiate into cardiomyocytes after myocardial infarction. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 582-9. PMID 21212399 DOI: 10.1161/Atvbaha.110.214726  0.381
2011 Igaki T, Kanda H, Okano H, Xu T, Miura M. Eiger and wengen: the Drosophila orthologs of TNF/TNFR. Advances in Experimental Medicine and Biology. 691: 45-50. PMID 21153308 DOI: 10.1007/978-1-4419-6612-4_5  0.354
2011 Shiozawa S, Kawai K, Okada Y, Tomioka I, Maeda T, Kanda A, Shinohara H, Suemizu H, James Okano H, Sotomaru Y, Sasaki E, Okano H. Gene targeting and subsequent site-specific transgenesis at the β-actin (ACTB) locus in common marmoset embryonic stem cells. Stem Cells and Development. 20: 1587-99. PMID 21126169 DOI: 10.1089/Scd.2010.0351  0.417
2011 Takahashi Y, Tsuji O, Kumagai G, Hara CM, Okano HJ, Miyawaki A, Toyama Y, Okano H, Nakamura M. Comparative study of methods for administering neural stem/progenitor cells to treat spinal cord injury in mice. Cell Transplantation. 20: 727-39. PMID 21054930 DOI: 10.3727/096368910X536554  0.331
2011 Hamanoue M, Okano H. Cell surface N-glycans-mediated isolation of mouse neural stem cells. Journal of Cellular Physiology. 226: 1433-8. PMID 20945342 DOI: 10.1111/J.1471-4159.2009.06256.X  0.374
2011 Miura K, Tsuji O, Nakamura M, Okano H. Toward using iPS cells to treat spinal cord injury: Their safety and therapeutic efficacy Inflammation and Regeneration. 31: 2-9. DOI: 10.2492/Inflammregen.31.2  0.407
2011 Niibe K, Morikawa S, Mabuchi Y, Araki D, Nakagawa T, Okano H, Matsuzaki Y. Mesp1+ early paraxial mesodermal cells supply initial bone marrow mesenchymal stem cells capable of differentiating into neural crest lineage cells Inflammation and Regeneration. 31: 116-124. DOI: 10.2492/Inflammregen.31.116  0.399
2011 Matsui T, Ohno S, Yoshida K, Matsuzaki Y, Akamatsu W, Okano H. Direct induction of safe neural stem cells from adult mouse fibroblasts Neuroscience Research. 71: e228. DOI: 10.1016/J.Neures.2011.07.994  0.398
2011 Ohta S, Misawa A, Okuno H, Fukuda K, Akamatsu W, Kawakami Y, Okano H. Generation of neural crest progenitor cells from human induced pluripotent stem cells by a simple method Neuroscience Research. 71: e127. DOI: 10.1016/J.Neures.2011.07.541  0.391
2011 Kuzumaki N, Narita M, Hamada Y, Nagasawa A, Okada Y, Akamatsu W, Okano HJ, Okano H, Narita M. Multiple analyses of G-protein coupled receptor (GPCR) expression in the neural differentiation from embryonic stem cells Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.537  0.368
2011 Yoshida K, Ota S, Hara C, Okada Y, Okano H. Generation and characterization of human ES cells carrying Sox1-reporter gene for neural differentiation Neuroscience Research. 71: e125. DOI: 10.1016/J.Neures.2011.07.534  0.383
2011 Namiki J, Suzuki S, Shibata S, Matsuzaki Y, Okano H. A vascular niche factor for neural stem cells of the mammalian brain Neuroscience Research. 71: e51. DOI: 10.1016/J.Neures.2011.07.215  0.362
2011 Hara K, Inoue S, Muto J, Kaneko N, Toyoda F, Hikishima K, Itoh T, Sawamoto K, Yoshida K, Kawase T, Okano H. Development and analysis of less invasive transient middle cerebral artery occlusion model on non-human primate Neuroscience Research. 71: e403-e404. DOI: 10.1016/J.Neures.2011.07.1768  0.623
2011 Nakaguchi K, Kaneko N, Aoyama M, Okada Y, Asai K, Okano H, Sawamoto K. Directional migration of new neurons generated by transplanted human iPS cell-derived neural stem cells in the striatum of a mouse stroke model Neuroscience Research. 71: e338. DOI: 10.1016/J.Neures.2011.07.1483  0.704
2011 Shimada H, Okada Y, Tomioka I, Sasaki E, Nakamura M, Okano H. Efficient derivation of neural stem cells from common marmoset ES cells and iPS cells Neuroscience Research. 71: e332. DOI: 10.1016/J.Neures.2011.07.1454  0.401
2011 Ishii S, Okada Y, Miya F, Tsunoda T, Shimazaki T, Okano H. Efficient generation and developmental analysis of basal forebrain cholinergic neurons from mouse embryonic stem cells Neuroscience Research. 71: e332. DOI: 10.1016/J.Neures.2011.07.1451  0.398
2011 Tsuboi D, Iizuka Y, Taya S, Shiina N, Okano H, Mikoshiba K, Kaibuchi K. Disrupted-in-Schizoprenia-1 regulates transport of neuronal mRNA for neural plasticity Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.1412  0.335
2010 Horisawa K, Imai T, Okano H, Yanagawa H. The Musashi family RNA-binding proteins in stem cells. Biomolecular Concepts. 1: 59-66. PMID 25961986 DOI: 10.1515/Bmc.2010.005  0.427
2010 Okano H. Investigation of regeneration of damaged CNS and neurological diseases mechanisms using iPS cells. Rinshå Shinkeigaku = Clinical Neurology. 50: 887. PMID 21921490 DOI: 10.5692/Clinicalneurol.50.887  0.435
2010 Yamamoto-Hino M, Kanie Y, Awano W, Aoki-Kinoshita KF, Yano H, Nishihara S, Okano H, Ueda R, Kanie O, Goto S. Identification of genes required for neural-specific glycosylation using functional genomics. Plos Genetics. 6: e1001254. PMID 21203496 DOI: 10.1371/Journal.Pgen.1001254  0.358
2010 Shibata S, Yasuda A, Renault-Mihara F, Suyama S, Katoh H, Inoue T, Inoue YU, Nagoshi N, Sato M, Nakamura M, Akazawa C, Okano H. Sox10-Venus mice: a new tool for real-time labeling of neural crest lineage cells and oligodendrocytes. Molecular Brain. 3: 31. PMID 21034515 DOI: 10.1186/1756-6606-3-31  0.418
2010 Ellis J, Baum C, Benvenisty N, Mostoslavsky G, Okano H, Stanford WL, Porteus M, Sadelain M. Benefits of utilizing gene-modified iPSCs for clinical applications. Cell Stem Cell. 7: 429-30. PMID 20887948 DOI: 10.1016/J.Stem.2010.09.010  0.356
2010 Ikeda M, Hirota Y, Sakaguchi M, Yamada O, Kida YS, Ogura T, Otsuka T, Okano H, Sawamoto K. Expression and proliferation-promoting role of Diversin in the neuronally committed precursor cells migrating in the adult mouse brain. Stem Cells (Dayton, Ohio). 28: 2017-26. PMID 20827749 DOI: 10.1002/Stem.516  0.772
2010 Wang XY, Penalva LO, Yuan H, Linnoila RI, Lu J, Okano H, Glazer RI. Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival. Molecular Cancer. 9: 221. PMID 20727204 DOI: 10.1186/1476-4598-9-221  0.316
2010 Aihara Y, Hayashi Y, Hirata M, Ariki N, Shibata S, Nagoshi N, Nakanishi M, Ohnuma K, Warashina M, Michiue T, Uchiyama H, Okano H, Asashima M, Furue MK. Induction of neural crest cells from mouse embryonic stem cells in a serum-free monolayer culture. The International Journal of Developmental Biology. 54: 1287-94. PMID 20711997 DOI: 10.1387/Ijdb.103173Ya  0.421
2010 Kuwako K, Kakumoto K, Imai T, Igarashi M, Hamakubo T, Sakakibara S, Tessier-Lavigne M, Okano HJ, Okano H. Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression. Neuron. 67: 407-21. PMID 20696379 DOI: 10.1016/J.Neuron.2010.07.005  0.352
2010 Hirota Y, Meunier A, Huang S, Shimozawa T, Yamada O, Kida YS, Inoue M, Ito T, Kato H, Sakaguchi M, Sunabori T, Nakaya MA, Nonaka S, Ogura T, Higuchi H, ... Okano H, et al. Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II. Development (Cambridge, England). 137: 3037-46. PMID 20685736 DOI: 10.1242/Dev.050120  0.737
2010 Kaneko N, Marín O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K. New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron. 67: 213-23. PMID 20670830 DOI: 10.1016/J.Neuron.2010.06.018  0.694
2010 Tomioka I, Maeda T, Shimada H, Kawai K, Okada Y, Igarashi H, Oiwa R, Iwasaki T, Aoki M, Kimura T, Shiozawa S, Shinohara H, Suemizu H, Sasaki E, Okano H. Generating induced pluripotent stem cells from common marmoset (Callithrix jacchus) fetal liver cells using defined factors, including Lin28. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 15: 959-69. PMID 20670273 DOI: 10.1111/J.1365-2443.2010.01437.X  0.423
2010 Sato T, Shimazaki T, Naka H, Fukami S, Satoh Y, Okano H, Lax I, Schlessinger J, Gotoh N. FRS2α regulates Erk levels to control a self-renewal target Hes1 and proliferation of FGF-responsive neural stem/progenitor cells. Stem Cells (Dayton, Ohio). 28: 1661-73. PMID 20652960 DOI: 10.1002/Stem.488  0.362
2010 Tsuji O, Miura K, Okada Y, Fujiyoshi K, Mukaino M, Nagoshi N, Kitamura K, Kumagai G, Nishino M, Tomisato S, Higashi H, Nagai T, Katoh H, Kohda K, Matsuzaki Y, ... ... Okano H, et al. Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury. Proceedings of the National Academy of Sciences of the United States of America. 107: 12704-9. PMID 20615974 DOI: 10.1073/Pnas.0910106107  0.392
2010 Mukaino M, Nakamura M, Yamada O, Okada S, Morikawa S, Renault-Mihara F, Iwanami A, Ikegami T, Ohsugi Y, Tsuji O, Katoh H, Matsuzaki Y, Toyama Y, Liu M, Okano H. Anti-IL-6-receptor antibody promotes repair of spinal cord injury by inducing microglia-dominant inflammation. Experimental Neurology. 224: 403-14. PMID 20478301 DOI: 10.1016/J.Expneurol.2010.04.020  0.32
2010 Masuda H, Matsuzaki Y, Hiratsu E, Ono M, Nagashima T, Kajitani T, Arase T, Oda H, Uchida H, Asada H, Ito M, Yoshimura Y, Maruyama T, Okano H. Stem cell-like properties of the endometrial side population: implication in endometrial regeneration. Plos One. 5: e10387. PMID 20442847 DOI: 10.1371/Journal.Pone.0010387  0.366
2010 Suzuki S, Namiki J, Shibata S, Mastuzaki Y, Okano H. The neural stem/progenitor cell marker nestin is expressed in proliferative endothelial cells, but not in mature vasculature. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 58: 721-30. PMID 20421592 DOI: 10.1369/Jhc.2010.955609  0.43
2010 Contini M, Lin B, Kobayashi K, Okano H, Masland RH, Raviola E. Synaptic input of ON-bipolar cells onto the dopaminergic neurons of the mouse retina. The Journal of Comparative Neurology. 518: 2035-50. PMID 20394057 DOI: 10.1002/Cne.22320  0.336
2010 Kurihara T, Kubota Y, Ozawa Y, Takubo K, Noda K, Simon MC, Johnson RS, Suematsu M, Tsubota K, Ishida S, Goda N, Suda T, Okano H. von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina. Development (Cambridge, England). 137: 1563-71. PMID 20388654 DOI: 10.1242/Dev.049015  0.302
2010 Sakaguchi M, Imaizumi Y, Shingo T, Tada H, Hayama K, Yamada O, Morishita T, Kadoya T, Uchiyama N, Shimazaki T, Kuno A, Poirier F, Hirabayashi J, Sawamoto K, Okano H. Regulation of adult neural progenitor cells by Galectin-1/beta1 Integrin interaction. Journal of Neurochemistry. 113: 1516-24. PMID 20367753 DOI: 10.1111/J.1471-4159.2010.06712.X  0.751
2010 Kohyama J, Sanosaka T, Tokunaga A, Takatsuka E, Tsujimura K, Okano H, Nakashima K. BMP-induced REST regulates the establishment and maintenance of astrocytic identity. The Journal of Cell Biology. 189: 159-70. PMID 20351065 DOI: 10.1083/Jcb.200908048  0.432
2010 Kanki H, Shimabukuro MK, Miyawaki A, Okano H. "Color Timer" mice: visualization of neuronal differentiation with fluorescent proteins. Molecular Brain. 3: 5. PMID 20205849 DOI: 10.1186/1756-6606-3-5  0.369
2010 Shindo A, Nakamura T, Matsumoto Y, Kawai N, Okano H, Nagao S, Itano T, Tamiya T. Seizure suppression in amygdala-kindled mice by transplantation of neural stem/progenitor cells derived from mouse embryonic stem cells. Neurologia Medico-Chirurgica. 50: 98-105; disucussion . PMID 20185872 DOI: 10.2176/Nmc.50.98  0.391
2010 Yamane J, Nakamura M, Iwanami A, Sakaguchi M, Katoh H, Yamada M, Momoshima S, Miyao S, Ishii K, Tamaoki N, Nomura T, Okano HJ, Kanemura Y, Toyama Y, Okano H. Transplantation of galectin-1-expressing human neural stem cells into the injured spinal cord of adult common marmosets. Journal of Neuroscience Research. 88: 1394-405. PMID 20091712 DOI: 10.1002/Jnr.22322  0.548
2010 Kiyokage E, Pan YZ, Shao Z, Kobayashi K, Szabo G, Yanagawa Y, Obata K, Okano H, Toida K, Puche AC, Shipley MT. Molecular identity of periglomerular and short axon cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1185-96. PMID 20089927 DOI: 10.1523/Jneurosci.3497-09.2010  0.368
2010 Kojima T, Hirota Y, Ema M, Takahashi S, Miyoshi I, Okano H, Sawamoto K. Subventricular zone-derived neural progenitor cells migrate along a blood vessel scaffold toward the post-stroke striatum. Stem Cells (Dayton, Ohio). 28: 545-54. PMID 20073084 DOI: 10.1002/Stem.306  0.686
2010 Oki K, Kaneko N, Kanki H, Imai T, Suzuki N, Sawamoto K, Okano H. Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia. Neuroscience Research. 66: 390-5. PMID 20036290 DOI: 10.1016/J.Neures.2009.12.013  0.709
2010 Terashima M, Kobayashi M, Motomiya M, Inoue N, Yoshida T, Okano H, Iwasaki N, Minami A, Matsuoka I. Analysis of the expression and function of BRINP family genes during neuronal differentiation in mouse embryonic stem cell-derived neural stem cells. Journal of Neuroscience Research. 88: 1387-93. PMID 20025061 DOI: 10.1002/Jnr.22315  0.453
2010 Ishii S, Okada Y, Kadoya T, Matsuzaki Y, Shimazaki T, Okano H. Stromal cell-secreted factors promote the survival of embryonic stem cell-derived early neural stem/progenitor cells via the activation of MAPK and PI3K-Akt pathways. Journal of Neuroscience Research. 88: 722-34. PMID 19798745 DOI: 10.1002/Jnr.22250  0.418
2010 Tao O, Shimazaki T, Okada Y, Naka H, Kohda K, Yuzaki M, Mizusawa H, Okano H. Efficient generation of mature cerebellar Purkinje cells from mouse embryonic stem cells. Journal of Neuroscience Research. 88: 234-47. PMID 19705453 DOI: 10.1002/Jnr.22208  0.388
2010 Murata J, Ohtsuka T, Tokunaga A, Nishiike S, Inohara H, Okano H, Kageyama R. Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1. Journal of Neuroscience Research. 87: 3521-34. PMID 19598246 DOI: 10.1002/Jnr.22169  0.412
2010 Konuma N, Wakabayashi K, Matsumoto T, Kusumi Y, Masuko T, Iribe Y, Mitsumata M, Okano H, Kusafuka T, Mugishima H. Mouse embryonic stem cells give rise to gut-like morphogenesis, including intestinal stem cells, in the embryoid body model. Stem Cells and Development. 18: 113-26. PMID 18680392 DOI: 10.1089/Scd.2008.0045  0.403
2010 Masuda H, Maruyama T, Yoshimura Y, Matsuzaki Y, Okano H. A novel model for endometriosis Inflammation and Regeneration. 30: 96-102. DOI: 10.2492/Inflammregen.30.96  0.344
2010 Shibata S, Okano H. New aspects on the migration and differentiation of neural crest stem cells Neuroscience Research. 68: e39. DOI: 10.1016/J.Neures.2010.07.415  0.379
2010 Adachi K, Nakamura K, Asami-Odaka A, Okada Y, Okano H, Nakanishi A. Drug discovery using human neurons derived from iPS cells Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.2167  0.343
2010 Suzuki A, Kuzumaki N, Narita M, Imai S, Okada Y, Okano JH, Okano H, Suzuki T, Narita M. Analysis of molecular mechanism underlying the control of ES cell differentiation by the stimulation of dopamine receptors located on embryonic stem cells Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.2166  0.35
2010 Kuzumaki N, Suzuki A, Narita M, Imai S, Okada Y, Okano JH, Okano H, Suzuki T, Narita M. Role of G-protein coupled receptors in the neural differentiation from embryonic stem cells Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.2165  0.361
2010 Sato M, Shibata S, Nagoshi N, Yasuda A, Naka-Kaneda H, Suzuki S, Mabuchi Y, Matsuzaki Y, Nakamura M, Toyama Y, Okano H. Comparison of the neural crest stem cell characteristics derived from dorsal root ganglia, whisker pad and bone marrow in neonate rodents Neuroscience Research. 68: e129. DOI: 10.1016/J.Neures.2010.07.2142  0.329
2010 Takahashi Y, Okada Y, Kumagai G, Tsuji O, Nori S, Yasuda A, Toyama Y, Nakamura M, Okano H. Transplantation of human embryonic stem cell derived-neural stem/progenitor cells for spinal cord injury in adult NOD/Scid mice Neuroscience Research. 68: e425. DOI: 10.1016/J.Neures.2010.07.1885  0.375
2010 Kaneko N, Marin O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K. New neurons form and maintain their path of astrocytic processes for rapid migration in the adult brain Neuroscience Research. 68: e93. DOI: 10.1016/J.Neures.2010.07.175  0.681
2010 Hirota Y, Meunier A, Huang S, Shimozawa T, Kida YS, Inoue M, Ito T, Kato H, Nakaya M, Nonaka S, Ogura T, Higuchi H, Okano H, Spassky N, Sawamoto K. Planar cell polarity of multiciliated ependymal cells regulated by non-muscle myosin II Neuroscience Research. 68: e364. DOI: 10.1016/J.Neures.2010.07.1614  0.667
2010 Hara K, Muto J, Kaneko N, Adachi K, Toyota F, Hikishima K, Itoh T, Sawamoto K, Kawase T, Yoshida K, Okano H. Development and analysis of less invasive transient middle cerebral artery occlusion model on Common Marmoset Neuroscience Research. 68: e320. DOI: 10.1016/J.Neures.2010.07.1418  0.622
2010 Hamanoue M, Mizuno T, Okano HJ, Okano H, Takamatsu K. Protein transduction of p38 MAP kinase enhances adult neural stem cell migration. Neuroscience Research. 68: e254. DOI: 10.1016/J.Neures.2010.07.1127  0.352
2010 Ohta S, Kawakami Y, Okano H, Toda M. Functional analysis of macrophage migration inhibitory factor (MIF) in the mouse neural stem/progenitor cells Neuroscience Research. 68: e245-e246. DOI: 10.1016/J.Neures.2010.07.1088  0.382
2010 Okano H. Strategies toward regeneration of damaged CNS using iPS cells Neuroscience Research. 68: e53. DOI: 10.1016/J.Neures.2010.07.007  0.324
2010 Okano H. O25. iPS based cell therapy for the damaged CNS. Differentiation. 80. DOI: 10.1016/J.Diff.2010.09.168  0.392
2010 Kanda H, Shimamura R, Okano H. P105. A genetic approach for the organization and function of the blood–brain barrier in Drosophila Differentiation. 80: S52. DOI: 10.1016/J.Diff.2010.09.111  0.317
2010 Yoshida S, Yasuda M, Miyashita M, Tetsu Y, Tsubota K, Okano H, Shimmura S. P82. Differentiation of induced pluripotent stem cells into corneal epithelial cells Differentiation. 80: S44-S45. DOI: 10.1016/J.Diff.2010.09.088  0.368
2010 Yoshida T, Koizumi H, Yuki K, Kubota S, Hirabayashi Y, Suzuki K, Mitani K, Kobayashi T, Ohyama M, Amagai M, Okada Y, Akamatsu W, Tsubota K, Shimmura S, Ozawa Y, ... Okano H, et al. P75. A gene therapy for a gene mutation in human iPS cell using helper-dependent adenoviral vector Differentiation. 80: S42. DOI: 10.1016/J.Diff.2010.09.081  0.398
2010 Orihara-Ono M, Okano H, Nakao K. P67. Conversion of Drosophila neuroepithelial stem cells into neuroblasts occurs during prolonged G1 phase, whose timing is regulated by Notch signaling Differentiation. 80: S39. DOI: 10.1016/J.Diff.2010.09.073  0.429
2010 Ohta S, Kawakami Y, Okano H, Toda M. P45. Functional analysis of macrophage migration inhibitory factor (MIF) in the mouse neural stem/progenitor cells Differentiation. 80: S32. DOI: 10.1016/J.Diff.2010.09.051  0.388
2009 Okano H. [Regeneration of the central nervous system using iPS cell-technologies]. Rinshå Shinkeigaku = Clinical Neurology. 49: 825-6. PMID 20030221 DOI: 10.5692/Clinicalneurol.49.825  0.427
2009 Sotomaru Y, Hirakawa R, Shimada A, Shiozawa S, Sugawara A, Oiwa R, Nobukiyo A, Okano H, Tamaoki N, Nomura T, Hiyama E, Sasaki E. Preimplantation development of somatic cell cloned embryos in the common marmoset (Callithrix jacchus). Cloning and Stem Cells. 11: 575-83. PMID 20025525 DOI: 10.1089/Clo.2009.0005  0.309
2009 Nakashima K, Kohyama J, Namihira M, Gage FH, Okano H, Sawamoto K. [Epigenetic mechanisms regulating neural cell fate determination]. No to Hattatsu. Brain and Development. 41: 411-4. PMID 19928537  0.723
2009 Kumagai G, Okada Y, Yamane J, Nagoshi N, Kitamura K, Mukaino M, Tsuji O, Fujiyoshi K, Katoh H, Okada S, Shibata S, Matsuzaki Y, Toh S, Toyama Y, Nakamura M, ... Okano H, et al. Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury. Plos One. 4: e7706. PMID 19893739 DOI: 10.1371/Journal.Pone.0007706  0.37
2009 Morikawa S, Mabuchi Y, Kubota Y, Nagai Y, Niibe K, Hiratsu E, Suzuki S, Miyauchi-Hara C, Nagoshi N, Sunabori T, Shimmura S, Miyawaki A, Nakagawa T, Suda T, Okano H, et al. Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow. The Journal of Experimental Medicine. 206: 2483-96. PMID 19841085 DOI: 10.1084/Jem.20091046  0.363
2009 Mine Y, Hayashi T, Yamada M, Okano H, Kawase T. Environmental cue-dependent dopaminergic neuronal differentiation and functional effect of grafted neuroepithelial stem cells in parkinsonian brain. Neurosurgery. 65: 741-53; discussion 7. PMID 19834380 DOI: 10.1227/01.Neu.0000351281.45986.76  0.363
2009 Tamase A, Muraguchi T, Naka K, Tanaka S, Kinoshita M, Hoshii T, Ohmura M, Shugo H, Ooshio T, Nakada M, Sawamoto K, Onodera M, Matsumoto K, Oshima M, Asano M, ... ... Okano H, et al. Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin. Proceedings of the National Academy of Sciences of the United States of America. 106: 17163-8. PMID 19805150 DOI: 10.1073/Pnas.0905016106  0.681
2009 Yaguchi M, Tabuse M, Ohta S, Ohkusu-Tsukada K, Takeuchi T, Yamane J, Katoh H, Nakamura M, Matsuzaki Y, Yamada M, Itoh T, Nomura T, Toyama Y, Okano H, Toda M. Transplantation of dendritic cells promotes functional recovery from spinal cord injury in common marmoset. Neuroscience Research. 65: 384-92. PMID 19737583 DOI: 10.1016/J.Neures.2009.08.016  0.302
2009 Takaoka T, Shiotani A, Saito K, Tomifuji M, Mori Y, Fujimine T, Okano H, Ogawa K. Neuronal re-juvenilization in the nucleus ambiguus after vagal nerve injury. Neuroscience Research. 65: 353-9. PMID 19723548 DOI: 10.1016/J.Neures.2009.08.012  0.381
2009 Miura K, Okada Y, Aoi T, Okada A, Takahashi K, Okita K, Nakagawa M, Koyanagi M, Tanabe K, Ohnuki M, Ogawa D, Ikeda E, Okano H, Yamanaka S. Variation in the safety of induced pluripotent stem cell lines. Nature Biotechnology. 27: 743-5. PMID 19590502 DOI: 10.1038/Nbt.1554  0.396
2009 Horisawa K, Imai T, Okano H, Yanagawa H. 3'-Untranslated region of doublecortin mRNA is a binding target of the Musashi1 RNA-binding protein. Febs Letters. 583: 2429-34. PMID 19573529 DOI: 10.1016/J.Febslet.2009.06.045  0.322
2009 Hamanoue M, Matsuzaki Y, Sato K, Okano HJ, Shibata S, Sato I, Suzuki S, Ogawara M, Takamatsu K, Okano H. Cell surface N-glycans mediated isolation of mouse neural stem cells. Journal of Neurochemistry. 110: 1575-84. PMID 19573022 DOI: 10.1111/j.1471-4159.2009.06256.x  0.327
2009 Oishia K, Watatani K, Itoh Y, Okano H, Guillemot F, Nakajima K, Gotoh Y. Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1 Proceedings of the National Academy of Sciences of the United States of America. 106: 13064-13069. PMID 19549840 DOI: 10.1073/Pnas.0808400106  0.382
2009 Nagoshi N, Shibata S, Nakamura M, Matsuzaki Y, Toyama Y, Okano H. Neural crest-derived stem cells display a wide variety of characteristics. Journal of Cellular Biochemistry. 107: 1046-52. PMID 19479900 DOI: 10.1002/Jcb.22213  0.357
2009 Kiso M, Tanaka S, Saba R, Matsuda S, Shimizu A, Ohyama M, Okano HJ, Shiroishi T, Okano H, Saga Y. The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 9292-7. PMID 19470461 DOI: 10.1073/Pnas.0808324106  0.377
2009 Tatsumi K, Tsuji S, Miwa H, Morisaku T, Nuriya M, Orihara M, Kaneko K, Okano H, Yasui M. Drosophila big brain does not act as a water channel, but mediates cell adhesion. Febs Letters. 583: 2077-82. PMID 19467350 DOI: 10.1016/J.Febslet.2009.05.035  0.367
2009 Okano H, Temple S. Cell types to order: temporal specification of CNS stem cells. Current Opinion in Neurobiology. 19: 112-9. PMID 19427192 DOI: 10.1016/J.Conb.2009.04.003  0.423
2009 Saiga T, Fukuda T, Matsumoto M, Tada H, Okano HJ, Okano H, Nakayama KI. Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development. Molecular and Cellular Biology. 29: 3529-43. PMID 19398581 DOI: 10.1128/Mcb.00364-09  0.334
2009 Yamamoto A, Shofuda T, Islam MO, Nakamura Y, Yamasaki M, Okano H, Kanemura Y. ABCB1 is predominantly expressed in human fetal neural stem/progenitor cells at an early development stage. Journal of Neuroscience Research. 87: 2615-23. PMID 19384922 DOI: 10.1002/Jnr.22094  0.376
2009 Taura D, Noguchi M, Sone M, Hosoda K, Mori E, Okada Y, Takahashi K, Homma K, Oyamada N, Inuzuka M, Sonoyama T, Ebihara K, Tamura N, Itoh H, Suemori H, ... ... Okano H, et al. Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. Febs Letters. 583: 1029-33. PMID 19250937 DOI: 10.1016/J.Febslet.2009.02.031  0.379
2009 Akamatsu W, DeVeale B, Okano H, Cooney AJ, van der Kooy D. Suppression of Oct4 by germ cell nuclear factor restricts pluripotency and promotes neural stem cell development in the early neural lineage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2113-24. PMID 19228964 DOI: 10.1523/Jneurosci.4527-08.2009  0.405
2009 Takenaga M, Ohta Y, Tokura Y, Hamaguchi A, Shudo K, Okano H, Igarashi R. The effect of Am-80, a synthetic retinoid, on spinal cord injury-induced motor dysfunction in rats. Biological & Pharmaceutical Bulletin. 32: 225-31. PMID 19182380 DOI: 10.1248/Bpb.32.225  0.383
2009 Morikawa S, Mabuchi Y, Niibe K, Suzuki S, Nagoshi N, Sunabori T, Shimmura S, Nagai Y, Nakagawa T, Okano H, Matsuzaki Y. Development of mesenchymal stem cells partially originate from the neural crest. Biochemical and Biophysical Research Communications. 379: 1114-9. PMID 19161980 DOI: 10.1016/J.Bbrc.2009.01.031  0.418
2009 Ohta Y, Takenaga M, Tokura Y, Hamaguchi A, Matsumoto T, Kano K, Mugishima H, Okano H, Igarashi R. Mature adipocyte-derived cells, dedifferentiated fat cells (DFAT), promoted functional recovery from spinal cord injury-induced motor dysfunction in rats. Cell Transplantation. 17: 877-86. PMID 19069631 DOI: 10.3727/096368908786576516  0.387
2009 Ogawa D, Okada Y, Nakamura M, Kanemura Y, Okano HJ, Matsuzaki Y, Shimazaki T, Ito M, Ikeda E, Tamiya T, Nagao S, Okano H. Evaluation of human fetal neural stem/progenitor cells as a source for cell replacement therapy for neurological disorders: properties and tumorigenicity after long-term in vitro maintenance. Journal of Neuroscience Research. 87: 307-17. PMID 18972448 DOI: 10.1002/Jnr.21843  0.339
2009 Fukuda K, Saikawa Y, Ohashi M, Kumagai K, Kitajima M, Okano H, Matsuzaki Y, Kitagawa Y. Tumor initiating potential of side population cells in human gastric cancer. International Journal of Oncology. 34: 1201-1207. DOI: 10.3892/Ijo_00000248  0.376
2009 Okada S, Nakamura M, Saiwai H, Kumamaru H, Toyama Y, Iwamoto Y, Okano H. Physiological significance of astrogliosis after CNS injury Inflammation and Regeneration. 29: 35-39. DOI: 10.2492/Inflammregen.29.35  0.308
2009 Mine Y, Hayashi T, Yamada M, Okano H, Kawase T. Erratum: Environmental cue-dependent dopaminergic neuronal differentiation and functional effect of grafted neuroepithelial stem cells in parkinsonian brain (Neurosurgery (2009) (741-753)) Neurosurgery. 65. DOI: 10.1227/01.Neu.0000345346.06073.Dd  0.39
2009 Yajima M, Kuzumaki N, Narita M, Narita M, Imai S, Okada Y, Okano JH, Okano H, Suzuki T. P2-a15Promotion of the neural differentiation from embryonic stem cells activated by dopamine D3 receptors Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.677  0.331
2009 Kuzumaki N, Narita M, Yajima M, Narita M, Imai S, Furuta S, Okada Y, Okano JH, Okano H, Suzuki T. Possible implication of μ-opioid receptors in the neural differentiation from embryonic stem cells Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.676  0.336
2009 Ohta S, Kawakami Y, Okano H, Kawase T, Toda M. Macrophage migration inhibitory factor (MIF) promotes proliferation and cell survival of neural stem/progenitor cells Neuroscience Research. 65: S91. DOI: 10.1016/J.Neures.2009.09.375  0.391
2009 Hamanoue M, Okano H, Okano H, Takamatsu K. Analysis of cell surface glycoproteins on neural stem cells Neuroscience Research. 65: S90-S91. DOI: 10.1016/J.Neures.2009.09.373  0.381
2009 Ikeda M, Hirota Y, Sakaguchi M, Yamada O, Kida Y, Ogura T, Otsuka T, Okano H, Sawamoto K. Role of Diversin as a possible switch of distinct Wnt pathways regulating multiple steps of adult neurogenesis Neuroscience Research. 65: S54. DOI: 10.1016/J.Neures.2009.09.129  0.724
2009 Hirota Y, Huang S, Yamada O, Kida Y, Ogura T, Spassky N, Nonaka S, Okano H, Sawamoto K. Planar polarity decisions for directional beating of ependymal cilia and fluid flow in the adult mouse lateral ventricles Neuroscience Research. 65: S54. DOI: 10.1016/J.Neures.2009.09.127  0.639
2009 Okano H. Strategies toward regenerating the damaged CNS using ES/iPS cells Neuroscience Research. 65: S1. DOI: 10.1016/J.Neures.2009.09.010  0.328
2008 Naka H, Nakamura S, Shimazaki T, Okano H. Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development. Nature Neuroscience. 11: 1014-23. PMID 19160499 DOI: 10.1038/Nn.2168  0.45
2008 Kohyama J, Kojima T, Takatsuka E, Yamashita T, Namiki J, Hsieh J, Gage FH, Namihira M, Okano H, Sawamoto K, Nakashima K. Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. Proceedings of the National Academy of Sciences of the United States of America. 105: 18012-7. PMID 19004774 DOI: 10.1073/Pnas.0808417105  0.748
2008 Okada Y, Matsumoto A, Shimazaki T, Enoki R, Koizumi A, Ishii S, Itoyama Y, Sobue G, Okano H. Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells. Stem Cells (Dayton, Ohio). 26: 3086-98. PMID 18757299 DOI: 10.1634/Stemcells.2008-0293  0.443
2008 Susaki K, Kaneko J, Yamano Y, Nakamura K, Inami W, Yoshikawa T, Ozawa Y, Shibata S, Matsuzaki O, Okano H, Chiba C. Musashi-1, an RNA-binding protein, is indispensable for survival of photoreceptors. Experimental Eye Research. 88: 347-55. PMID 18662689 DOI: 10.1016/J.Exer.2008.06.019  0.396
2008 Miyagi S, Masui S, Niwa H, Saito T, Shimazaki T, Okano H, Nishimoto M, Muramatsu M, Iwama A, Okuda A. Consequence of the loss of Sox2 in the developing brain of the mouse. Febs Letters. 582: 2811-5. PMID 18638478 DOI: 10.1016/J.Febslet.2008.07.011  0.414
2008 Valentin-Vega YA, Okano H, Lozano G. The intestinal epithelium compensates for p53-mediated cell death and guarantees organismal survival. Cell Death and Differentiation. 15: 1772-81. PMID 18636077 DOI: 10.1038/Cdd.2008.109  0.345
2008 Ozawa Y, Nakao K, Kurihara T, Shimazaki T, Shimmura S, Ishida S, Yoshimura A, Tsubota K, Okano H. Roles of STAT3/SOCS3 pathway in regulating the visual function and ubiquitin-proteasome-dependent degradation of rhodopsin during retinal inflammation. The Journal of Biological Chemistry. 283: 24561-70. PMID 18614536 DOI: 10.1074/Jbc.M802238200  0.316
2008 Kanaya T, Miyazawa K, Takakura I, Itani W, Watanabe K, Ohwada S, Kitazawa H, Rose MT, McConochie HR, Okano H, Yamaguchi T, Aso H. Differentiation of a murine intestinal epithelial cell line (MIE) toward the M cell lineage. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G273-84. PMID 18556421 DOI: 10.1152/Ajpgi.00378.2007  0.342
2008 Sato Y, Watanabe T, Saito D, Takahashi T, Yoshida S, Kohyama J, Ohata E, Okano H, Takahashi Y. Notch mediates the segmental specification of angioblasts in somites and their directed migration toward the dorsal aorta in avian embryos. Developmental Cell. 14: 890-901. PMID 18539117 DOI: 10.1016/J.Devcel.2008.03.024  0.378
2008 Deguchi K, Clewing JM, Elizondo LI, Hirano R, Huang C, Choi K, Sloan EA, Lücke T, Marwedel KM, Powell RD, Santa Cruz K, Willaime-Morawek S, Inoue K, Lou S, Northrop JL, ... ... Okano H, et al. Neurologic phenotype of Schimke immuno-osseous dysplasia and neurodevelopmental expression of SMARCAL1. Journal of Neuropathology and Experimental Neurology. 67: 565-77. PMID 18520775 DOI: 10.1097/Nen.0B013E3181772777  0.373
2008 Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K, Okano H. Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP. The Journal of Cell Biology. 181: 639-53. PMID 18490513 DOI: 10.1083/Jcb.200708004  0.348
2008 Kawagishi H, Wakoh T, Uno H, Maruyama M, Moriya A, Morikawa S, Okano H, Sherr CJ, Takagi M, Sugimoto M. Hzf regulates adipogenesis through translational control of C/EBPalpha. The Embo Journal. 27: 1481-90. PMID 18418387 DOI: 10.1038/Emboj.2008.76  0.323
2008 Nagoshi N, Shibata S, Kubota Y, Nakamura M, Nagai Y, Satoh E, Morikawa S, Okada Y, Mabuchi Y, Katoh H, Okada S, Fukuda K, Suda T, Matsuzaki Y, Toyama Y, ... Okano H, et al. Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad. Cell Stem Cell. 2: 392-403. PMID 18397758 DOI: 10.1016/J.Stem.2008.03.005  0.432
2008 Hara C, Tateyama K, Akamatsu N, Imabayashi H, Karaki K, Nomura N, Okano H, Miyawaki A. A practical device for pinpoint delivery of molecules into multiple neurons in culture. Brain Cell Biology. 35: 229-37. PMID 18392728 DOI: 10.1007/S11068-008-9021-Z  0.318
2008 Wang XY, Yin Y, Yuan H, Sakamaki T, Okano H, Glazer RI. Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated activation of the Wnt and Notch pathways. Molecular and Cellular Biology. 28: 3589-99. PMID 18362162 DOI: 10.1128/Mcb.00040-08  0.42
2008 Sunabori T, Tokunaga A, Nagai T, Sawamoto K, Okabe M, Miyawaki A, Matsuzaki Y, Miyata T, Okano H. Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors. Journal of Cell Science. 121: 1204-12. PMID 18349072 DOI: 10.1242/Jcs.025064  0.781
2008 Okano H, Sawamoto K. Neural stem cells: involvement in adult neurogenesis and CNS repair. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 2111-22. PMID 18339601 DOI: 10.1098/Rstb.2008.2264  0.726
2008 Ma D, Lu L, Boneva NB, Warashina S, Kaplamadzhiev DB, Mori Y, Nakaya MA, Kikuchi M, Tonchev AB, Okano H, Yamashima T. Expression of free fatty acid receptor GPR40 in the neurogenic niche of adult monkey hippocampus. Hippocampus. 18: 326-33. PMID 18064707 DOI: 10.1002/Hipo.20393  0.393
2008 Ohta S, Ueda Y, Yaguchi M, Matsuzaki Y, Nakamura M, Toyama Y, Tanioka Y, Tamaoki N, Nomura T, Okano H, Kawakami Y, Toda M. Isolation and characterization of dendritic cells from common marmosets for preclinical cell therapy studies. Immunology. 123: 566-74. PMID 18005037 DOI: 10.1111/J.1365-2567.2007.02727.X  0.321
2008 Murata H, Tsuji S, Tsujii M, Nakamura T, Fu HY, Eguchi H, Asahi K, Okano H, Kawano S, Hayashi N. Helicobacter pylori infection induces candidate stem cell marker Musashi-1 in the human gastric epithelium. Digestive Diseases and Sciences. 53: 363-9. PMID 17549630 DOI: 10.1007/S10620-007-9858-5  0.368
2008 Hayakawa-Yano Y, Shimazaki T, Okano H. Regulation of neural progenitor proliferation by EGF signaling in the spinal cord Inflammation and Regeneration. 28: 447-453. DOI: 10.2492/Inflammregen.28.447  0.4
2008 Naka H, Nakamura S, Shimazaki T, Okano H. Generation of neurospheres from embryonic stem cells for investigating the temporal specification of neural stem/progenitor cells Nature Protocols. DOI: 10.1038/Nprot.2008.168  0.376
2007 Hirota Y, Ohshima T, Kaneko N, Ikeda M, Iwasato T, Kulkarni AB, Mikoshiba K, Okano H, Sawamoto K. Cyclin-dependent kinase 5 is required for control of neuroblast migration in the postnatal subventricular zone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12829-38. PMID 18032654 DOI: 10.1523/Jneurosci.1014-07.2007  0.697
2007 Ono M, Maruyama T, Masuda H, Kajitani T, Nagashima T, Arase T, Ito M, Ohta K, Uchida H, Asada H, Yoshimura Y, Okano H, Matsuzaki Y. Side population in human uterine myometrium displays phenotypic and functional characteristics of myometrial stem cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 18700-5. PMID 18003928 DOI: 10.1073/Pnas.0704472104  0.401
2007 Hattori Y, Ohta S, Hamada K, Yamada-Okabe H, Kanemura Y, Matsuzaki Y, Okano H, Kawakami Y, Toda M. Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1. Biochemical and Biophysical Research Communications. 364: 737-42. PMID 17981261 DOI: 10.1016/J.Bbrc.2007.10.041  0.422
2007 Okano H. Isolation and identification of putative stem/progenitor cells from human cycling endometrium. Journal of Obstetrics and Gynaecology Research. 33. PMID 17845366 DOI: 10.1111/J.1447-0756.2007.00613.X  0.335
2007 Ishibashi S, Kuroiwa T, Sakaguchi M, Sun L, Kadoya T, Okano H, Mizusawa H. Galectin-1 regulates neurogenesis in the subventricular zone and promotes functional recovery after stroke. Experimental Neurology. 207: 302-13. PMID 17706645 DOI: 10.1016/J.Expneurol.2007.06.024  0.585
2007 Okano H, Sakaguchi M, Ohki K, Suzuki N, Sawamoto K. Regeneration of the central nervous system using endogenous repair mechanisms. Journal of Neurochemistry. 102: 1459-65. PMID 17697047 DOI: 10.1111/J.1471-4159.2007.04674.X  0.763
2007 Marumo T, Hishikawa K, Matsuzaki Y, Imai N, Takase O, Shimosawa T, Okano H, Fujita T. Angiotensin II type 1 receptor blockade prevents decrease in adult stem-like cells in kidney after ureteral obstruction. European Journal of Pharmacology. 573: 216-20. PMID 17692840 DOI: 10.1016/J.Ejphar.2007.07.032  0.31
2007 Fujita J, Mori M, Kawada H, Ieda Y, Tsuma M, Matsuzaki Y, Kawaguchi H, Yagi T, Yuasa S, Endo J, Hotta T, Ogawa S, Okano H, Yozu R, Ando K, et al. Administration of granulocyte colony-stimulating factor after myocardial infarction enhances the recruitment of hematopoietic stem cell-derived myofibroblasts and contributes to cardiac repair. Stem Cells (Dayton, Ohio). 25: 2750-9. PMID 17690181 DOI: 10.1634/Stemcells.2007-0275  0.308
2007 Adachi K, Mirzadeh Z, Sakaguchi M, Yamashita T, Nikolcheva T, Gotoh Y, Peltz G, Gong L, Kawase T, Alvarez-Buylla A, Okano H, Sawamoto K. Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone. Stem Cells (Dayton, Ohio). 25: 2827-36. PMID 17673525 DOI: 10.1634/Stemcells.2007-0177  0.772
2007 Imai N, Hishikawa K, Marumo T, Hirahashi J, Inowa T, Matsuzaki Y, Okano H, Kitamura T, Salant D, Fujita T. Inhibition of histone deacetylase activates side population cells in kidney and partially reverses chronic renal injury. Stem Cells (Dayton, Ohio). 25: 2469-75. PMID 17641247 DOI: 10.1634/Stemcells.2007-0049  0.319
2007 Nakano A, Kanemura Y, Mori K, Kodama E, Yamamoto A, Sakamoto H, Nakamura Y, Okano H, Yamasaki M, Arita N. Expression of the Neural RNA-binding protein Musashi1 in pediatric brain tumors. Pediatric Neurosurgery. 43: 279-84. PMID 17627143 DOI: 10.1159/000103307  0.336
2007 Bolognani F, Tanner DC, Nixon S, Okano HJ, Okano H, Perrone-Bizzozero NI. Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity. Neurochemical Research. 32: 2142-51. PMID 17577668 DOI: 10.1007/S11064-007-9388-8  0.351
2007 Takenaga M, Ohta Y, Tokura Y, Hamaguchi A, Suzuki N, Nakamura M, Okano H, Igarashi R. Plasma as a scaffold for regeneration of neural precursor cells after transplantation into rats with spinal cord injury. Cell Transplantation. 16: 57-65. PMID 17436855 DOI: 10.3727/000000007783464434  0.358
2007 Watanabe K, Kondo K, Takeuchi N, Okano H, Yamasoba T. Musashi-1 expression in postnatal mouse olfactory epithelium. Neuroreport. 18: 641-4. PMID 17426590 DOI: 10.1097/Wnr.0B013E3280Bef7E2  0.365
2007 Iijima T, Ogura H, Takatsuki K, Kawahara S, Wakabayashi K, Nakayama D, Fujioka M, Kimura Y, Bernstein A, Okano HJ, Kirino Y, Okano H. Impaired motor functions in mice lacking the RNA-binding protein Hzf. Neuroscience Research. 58: 183-9. PMID 17383763 DOI: 10.1016/J.Neures.2007.02.013  0.335
2007 Sakaguchi M, Imaizumi Y, Okano H. Expression and function of galectin-1 in adult neural stem cells. Cellular and Molecular Life Sciences : Cmls. 64: 1254-8. PMID 17364145 DOI: 10.1007/S00018-007-6476-5  0.592
2007 Hayakawa-Yano Y, Nishida K, Fukami S, Gotoh Y, Hirano T, Nakagawa T, Shimazaki T, Okano H. Epidermal growth factor signaling mediated by grb2 associated binder1 is required for the spatiotemporally regulated proliferation of olig2-expressing progenitors in the embryonic spinal cord. Stem Cells (Dayton, Ohio). 25: 1410-22. PMID 17332510 DOI: 10.1634/Stemcells.2006-0584  0.362
2007 Kohno D, Nakata M, Maekawa F, Fujiwara K, Maejima Y, Kuramochi M, Shimazaki T, Okano H, Onaka T, Yada T. Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway. Endocrinology. 148: 2251-63. PMID 17303662 DOI: 10.1210/En.2006-1240  0.309
2007 Masuda H, Maruyama T, Hiratsu E, Yamane J, Iwanami A, Nagashima T, Ono M, Miyoshi H, Okano HJ, Ito M, Tamaoki N, Nomura T, Okano H, Matsuzaki Y, Yoshimura Y. Noninvasive and real-time assessment of reconstructed functional human endometrium in NOD/SCID/gamma c(null) immunodeficient mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 1925-30. PMID 17261813 DOI: 10.1073/Pnas.0604310104  0.345
2007 Kanai R, Tomita H, Hirose Y, Ohba S, Goldman S, Okano H, Kawase T, Yazaki T. Augmented therapeutic efficacy of an oncolytic herpes simplex virus type 1 mutant expressing ICP34.5 under the transcriptional control of musashi1 promoter in the treatment of malignant glioma. Human Gene Therapy. 18: 63-73. PMID 17238803 DOI: 10.1089/Hum.2006.107  0.324
2007 Koide Y, Morikawa S, Mabuchi Y, Muguruma Y, Hiratsu E, Hasegawa K, Kobayashi M, Ando K, Kinjo K, Okano H, Matsuzaki Y. Two distinct stem cell lineages in murine bone marrow. Stem Cells (Dayton, Ohio). 25: 1213-21. PMID 17218403 DOI: 10.1634/Stemcells.2006-0325  0.403
2007 Ozawa Y, Nakao K, Shimazaki T, Shimmura S, Kurihara T, Ishida S, Yoshimura A, Tsubota K, Okano H. SOCS3 is required to temporally fine-tune photoreceptor cell differentiation. Developmental Biology. 303: 591-600. PMID 17198696 DOI: 10.1016/J.Ydbio.2006.11.032  0.371
2007 Higashiyama R, Inagaki Y, Hong YY, Kushida M, Nakao S, Niioka M, Watanabe T, Okano H, Matsuzaki Y, Shiota G, Okazaki I. Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice. Hepatology (Baltimore, Md.). 45: 213-22. PMID 17187438 DOI: 10.1002/Hep.21477  0.305
2007 Ohta S, Okano H, Kawase T, Toda M. Sox6 is expressed in mouse embryonic neural stem/progenitor cells (NSPCs) and contributes to their maintenance and/or survival Neuroscience Research. 58: S199. DOI: 10.1016/J.Neures.2007.06.896  0.403
2007 Sunabori T, Okano H. Signals regulating the differentiation vs. maintenance of neural progenitor cells Neuroscience Research. 58: S19. DOI: 10.1016/J.Neures.2007.06.109  0.391
2007 Nakashima K, Takatsuka E, Yamashita T, Hsieh J, Gage FH, Namihira M, Okano H, Sawamoto K, Kohyama J. Epigenetic mechanism regulating fate specification and plasticity of neural cells Neuroscience Research. 58. DOI: 10.1016/J.Neures.2007.06.108  0.702
2006 Jomphe C, Lemelin PL, Okano H, Kobayashi K, Trudeau LE. Bidirectional regulation of dopamine D2 and neurotensin NTS1 receptors in dopamine neurons European Journal of Neuroscience. 24: 2789-2800. PMID 17116165 DOI: 10.1111/J.1460-9568.2006.05151.X  0.318
2006 Yamada M, Tanemura K, Okada S, Iwanami A, Nakamura M, Mizuno H, Ozawa M, Ohyama-Goto R, Kitamura N, Kawano M, Tan-Takeuchi K, Ohtsuka C, Miyawaki A, Takashima A, Ogawa M, ... ... Okano H, et al. Electrical stimulation modulates fate determination of differentiating embryonic stem cells. Stem Cells (Dayton, Ohio). 25: 562-70. PMID 17110622 DOI: 10.1634/Stemcells.2006-0011  0.438
2006 Yamashita T, Deguchi K, Sawamoto K, Okano H, Kamiya T, Abe K. Neuroprotection and neurosupplementation in ischaemic brain. Biochemical Society Transactions. 34: 1310-2. PMID 17073809 DOI: 10.1042/Bst0341310  0.688
2006 Mori H, Ninomiya K, Kino-oka M, Shofuda T, Islam MO, Yamasaki M, Okano H, Taya M, Kanemura Y. Effect of neurosphere size on the growth rate of human neural stem/progenitor cells. Journal of Neuroscience Research. 84: 1682-91. PMID 17044035 DOI: 10.1002/Jnr.21082  0.36
2006 Ishii K, Nakamura M, Dai H, Finn TP, Okano H, Toyama Y, Bregman BS. Neutralization of ciliary neurotrophic factor reduces astrocyte production from transplanted neural stem cells and promotes regeneration of corticospinal tract fibers in spinal cord injury. Journal of Neuroscience Research. 84: 1669-81. PMID 17044031 DOI: 10.1002/Jnr.21079  0.354
2006 Kaneko N, Okano H, Sawamoto K. Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 11: 1145-59. PMID 16999735 DOI: 10.1111/J.1365-2443.2006.01010.X  0.707
2006 Yamashima T, Popivanova BK, Guo J, Kotani S, Wakayama T, Iseki S, Sawamoto K, Okano H, Fujii C, Mukaida N, Tonchev AB. Implication of "Down syndrome cell adhesion molecule" in the hippocampal neurogenesis of ischemic monkeys. Hippocampus. 16: 924-35. PMID 16983647 DOI: 10.1002/Hipo.20223  0.73
2006 Sasaki T, Kitagawa K, Yagita Y, Sugiura S, Omura-Matsuoka E, Tanaka S, Matsushita K, Okano H, Tsujimoto Y, Hori M. Bcl2 enhances survival of newborn neurons in the normal and ischemic hippocampus. Journal of Neuroscience Research. 84: 1187-96. PMID 16941650 DOI: 10.1002/Jnr.21036  0.352
2006 Yoshida S, Shimmura S, Nagoshi N, Fukuda K, Matsuzaki Y, Okano H, Tsubota K. Isolation of multipotent neural crest-derived stem cells from the adult mouse cornea. Stem Cells (Dayton, Ohio). 24: 2714-22. PMID 16888282 DOI: 10.1634/stemcells.2006-0156  0.3
2006 Arata Y, Kouike H, Zhang Y, Herman MA, Okano H, Sawa H. Wnt signaling and a Hox protein cooperatively regulate psa-3/Meis to determine daughter cell fate after asymmetric cell division in C. elegans. Developmental Cell. 11: 105-15. PMID 16824957 DOI: 10.1016/J.Devcel.2006.04.020  0.404
2006 Okada S, Nakamura M, Katoh H, Miyao T, Shimazaki T, Ishii K, Yamane J, Yoshimura A, Iwamoto Y, Toyama Y, Okano H. Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury. Nature Medicine. 12: 829-34. PMID 16783372 DOI: 10.1038/Nm1425  0.337
2006 Chan C, Moore BE, Cotman CW, Okano H, Tavares R, Hovanesian V, Pinar H, Johanson CE, Svendsen CN, Stopa EG. Musashi1 antigen expression in human fetal germinal matrix development. Experimental Neurology. 201: 515-8. PMID 16777095 DOI: 10.1016/J.Expneurol.2006.04.023  0.42
2006 Yamashita T, Ninomiya M, Hernández Acosta P, García-Verdugo JM, Sunabori T, Sakaguchi M, Adachi K, Kojima T, Hirota Y, Kawase T, Araki N, Abe K, Okano H, Sawamoto K. Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6627-36. PMID 16775151 DOI: 10.1523/Jneurosci.0149-06.2006  0.779
2006 Murata J, Tokunaga A, Okano H, Kubo T. Mapping of notch activation during cochlear development in mice: implications for determination of prosensory domain and cell fate diversification. The Journal of Comparative Neurology. 497: 502-18. PMID 16736472 DOI: 10.1002/Cne.20997  0.407
2006 Ninomiya M, Yamashita T, Araki N, Okano H, Sawamoto K. Enhanced neurogenesis in the ischemic striatum following EGF-induced expansion of transit-amplifying cells in the subventricular zone. Neuroscience Letters. 403: 63-7. PMID 16701951 DOI: 10.1016/J.Neulet.2006.04.039  0.717
2006 Sakaguchi M, Shingo T, Shimazaki T, Okano HJ, Shiwa M, Ishibashi S, Oguro H, Ninomiya M, Kadoya T, Horie H, Shibuya A, Mizusawa H, Poirier F, Nakauchi H, Sawamoto K, ... Okano H, et al. A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 7112-7. PMID 16636291 DOI: 10.1073/Pnas.0508793103  0.773
2006 Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, Mizushima N. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature. 441: 885-9. PMID 16625204 DOI: 10.1038/Nature04724  0.366
2006 Tonchev AB, Yamashima T, Sawamoto K, Okano H. Transcription factor protein expression patterns by neural or neuronal progenitor cells of adult monkey subventricular zone. Neuroscience. 139: 1355-67. PMID 16580139 DOI: 10.1016/J.Neuroscience.2006.01.053  0.75
2006 Miyagi S, Nishimoto M, Saito T, Ninomiya M, Sawamoto K, Okano H, Muramatsu M, Oguro H, Iwama A, Okuda A. The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon. The Journal of Biological Chemistry. 281: 13374-81. PMID 16547000 DOI: 10.1074/Jbc.M512669200  0.73
2006 Rawal N, Castelo-Branco G, Sousa KM, Kele J, Kobayashi K, Okano H, Arenas E. Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain. Experimental Cell Research. 312: 1626-36. PMID 16510140 DOI: 10.1016/J.Yexcr.2006.01.032  0.393
2006 Toriya M, Tokunaga A, Sawamoto K, Nakao K, Okano H. Distinct functions of human numb isoforms revealed by misexpression in the neural stem cell lineage in the Drosophila larval brain. Developmental Neuroscience. 28: 142-55. PMID 16508311 DOI: 10.1159/000090760  0.75
2006 Kawada H, Takizawa S, Takanashi T, Morita Y, Fujita J, Fukuda K, Takagi S, Okano H, Ando K, Hotta T. Administration of hematopoietic cytokines in the subacute phase after cerebral infarction is effective for functional recovery facilitating proliferation of intrinsic neural stem/progenitor cells and transition of bone marrow-derived neuronal cells. Circulation. 113: 701-10. PMID 16461843 DOI: 10.1161/Circulationaha.105.563668  0.407
2006 Okano H. [Identification of neural stem cells in adult human brain: its implication in the strategy for repairing the damaged central nervous system]. Rinsho Shinkeigaku = Clinical Neurology. 45: 871-3. PMID 16447749  0.342
2006 Sawamoto K, Wichterle H, Gonzalez-Perez O, Cholfin JA, Yamada M, Spassky N, Murcia NS, Garcia-Verdugo JM, Marin O, Rubenstein JL, Tessier-Lavigne M, Okano H, Alvarez-Buylla A. New neurons follow the flow of cerebrospinal fluid in the adult brain. Science (New York, N.Y.). 311: 629-32. PMID 16410488 DOI: 10.1126/Science.1119133  0.686
2006 Sugiyama-Nakagiri Y, Akiyama M, Shibata S, Okano H, Shimizu H. Expression of RNA-binding protein Musashi in hair follicle development and hair cycle progression. The American Journal of Pathology. 168: 80-92. PMID 16400011 DOI: 10.2353/Ajpath.2006.050469  0.437
2006 Nishimura T, Yamaguchi T, Tokunaga A, Hara A, Hamaguchi T, Kato K, Iwamatsu A, Okano H, Kaibuchi K. Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2. Molecular Biology of the Cell. 17: 1273-85. PMID 16394100 DOI: 10.1091/Mbc.E05-07-0700  0.349
2006 Matsumoto A, Okada Y, Nakamichi M, Nakamura M, Toyama Y, Sobue G, Nagai M, Aoki M, Itoyama Y, Okano H. Disease progression of human SOD1 (G93A) transgenic ALS model rats. Journal of Neuroscience Research. 83: 119-33. PMID 16342121 DOI: 10.1002/Jnr.20708  0.302
2006 Fukuhara Y, Li XK, Kitazawa Y, Inagaki M, Matsuoka K, Kosuga M, Kosaki R, Shimazaki T, Endo H, Umezawa A, Okano H, Takahashi T, Okuyama T. Histopathological and behavioral improvement of murine mucopolysaccharidosis type VII by intracerebral transplantation of neural stem cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 548-55. PMID 16316785 DOI: 10.1016/J.Ymthe.2005.09.020  0.366
2006 Okano H, Okada S, Nakamura M, Toyama Y. Neural stem cells and regeneration of injured spinal cord. Kidney International. 68: 1927-31. PMID 16221167 DOI: 10.1111/J.1523-1755.2005.00621.X  0.38
2006 Okano H, Nakamura M, Toyama Y. Stem cell therapies for injured spinal cord Ensho Saisei. 26: 18-28. DOI: 10.2492/Jsir.26.18  0.348
2006 Yazaki T, Kanai R, Okano H, Kawase T. 936. Novel Oncolytic HSV-1 Mutant Expressing ICP 34.5 under the Transcriptional Control of Musashi1 Promoter for the Treatment of Gliomas Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.1027  0.354
2005 Ikegami T, Nakamura M, Yamane J, Katoh H, Okada S, Iwanami A, Watanabe K, Ishii K, Kato F, Fujita H, Takahashi T, Okano HJ, Toyama Y, Okano H. Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances graft cell migration and outgrowth of growth-associated protein-43-positive fibers after rat spinal cord injury. The European Journal of Neuroscience. 22: 3036-46. PMID 16367770 DOI: 10.1111/J.1460-9568.2005.04492.X  0.324
2005 Nagata H, Akiba Y, Suzuki H, Okano H, Hibi T. Expression of Musashi-1 in the rat stomach and changes during mucosal injury and restitution. Febs Letters. 580: 27-33. PMID 16360154 DOI: 10.1016/J.Febslet.2005.11.041  0.418
2005 Asai R, Okano H, Yasugi S. Correlation between Musashi-1 and c-hairy-1 expression and cell proliferation activity in the developing intestine and stomach of both chicken and mouse. Development, Growth & Differentiation. 47: 501-10. PMID 16287482 DOI: 10.1111/J.1440-169X.2005.00825.X  0.417
2005 Kanuka H, Hiratou T, Igaki T, Kanda H, Kuranaga E, Sawamoto K, Aigaki T, Okano H, Miura M. Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity. Biochimica Et Biophysica Acta. 1726: 225-37. PMID 16243437 DOI: 10.1016/J.Bbagen.2005.06.020  0.727
2005 Yamamoto S, Yoshino I, Shimazaki T, Murohashi M, Hevner RF, Lax I, Okano H, Shibuya M, Schlessinger J, Gotoh N. Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 15983-8. PMID 16239343 DOI: 10.1073/Pnas.0507961102  0.461
2005 Kanuka H, Kuranaga E, Takemoto K, Hiratou T, Okano H, Miura M. Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development. The Embo Journal. 24: 3793-806. PMID 16222340 DOI: 10.1038/Sj.Emboj.7600822  0.372
2005 Sasaki T, Iwata S, Okano HJ, Urasaki Y, Hamada J, Tanaka H, Dang NH, Okano H, Morimoto C. Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats: possible involvement of Nedd9 in the differentiation of neurons after ischemia. Stroke. 36: 2457-62. PMID 16210561 DOI: 10.1161/01.Str.0000185672.10390.30  0.361
2005 Suzuki T, Izumoto S, Wada K, Fujimoto Y, Maruno M, Yamasaki M, Kanemura Y, Shimazaki T, Okano H, Yoshimine T. Inhibition of glioma cell proliferation by neural stem cell factor. Journal of Neuro-Oncology. 74: 233-9. PMID 16187020 DOI: 10.1007/S11060-004-7118-5  0.409
2005 Tomita Y, Matsumura K, Wakamatsu Y, Matsuzaki Y, Shibuya I, Kawaguchi H, Ieda M, Kanakubo S, Shimazaki T, Ogawa S, Osumi N, Okano H, Fukuda K. Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart. The Journal of Cell Biology. 170: 1135-46. PMID 16186259 DOI: 10.1083/Jcb.200504061  0.435
2005 Akasaka Y, Saikawa Y, Fujita K, Kubota T, Ishikawa Y, Fujimoto A, Ishii T, Okano H, Kitajima M. Expression of a candidate marker for progenitor cells, Musashi‐1, in the proliferative regions of human antrum and its decreased expression in intestinal metaplasia Histopathology. 47: 348-356. PMID 16178889 DOI: 10.1111/J.1365-2559.2005.02223.X  0.434
2005 Kohyama J, Tokunaga A, Fujita Y, Miyoshi H, Nagai T, Miyawaki A, Nakao K, Matsuzaki Y, Okano H. Visualization of spatiotemporal activation of Notch signaling: live monitoring and significance in neural development. Developmental Biology. 286: 311-25. PMID 16153632 DOI: 10.1016/J.Ydbio.2005.08.003  0.377
2005 Okada S, Ishii K, Yamane J, Iwanami A, Ikegami T, Katoh H, Iwamoto Y, Nakamura M, Miyoshi H, Okano HJ, Contag CH, Toyama Y, Okano H. In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1839-41. PMID 16141363 DOI: 10.1096/Fj.05-4082Fje  0.344
2005 Nakamura M, Okada S, Toyama Y, Okano H. Role of IL-6 in spinal cord injury in a mouse model. Clinical Reviews in Allergy & Immunology. 28: 197-204. PMID 16129904 DOI: 10.1385/Criai:28:3:197  0.321
2005 Sasaki E, Hanazawa K, Kurita R, Akatsuka A, Yoshizaki T, Ishii H, Tanioka Y, Ohnishi Y, Suemizu H, Sugawara A, Tamaoki N, Izawa K, Nakazaki Y, Hamada H, Suemori H, ... ... Okano H, et al. Establishment of novel embryonic stem cell lines derived from the common marmoset (Callithrix jacchus). Stem Cells (Dayton, Ohio). 23: 1304-13. PMID 16109758 DOI: 10.1634/Stemcells.2004-0366  0.353
2005 Tonchev AB, Yamashima T, Sawamoto K, Okano H. Enhanced proliferation of progenitor cells in the subventricular zone and limited neuronal production in the striatum and neocortex of adult macaque monkeys after global cerebral ischemia. Journal of Neuroscience Research. 81: 776-88. PMID 16047371 DOI: 10.1002/Jnr.20604  0.728
2005 Crespel A, Rigau V, Coubes P, Rousset MC, de Bock F, Okano H, Baldy-Moulinier M, Bockaert J, Lerner-Natoli M. Increased number of neural progenitors in human temporal lobe epilepsy. Neurobiology of Disease. 19: 436-50. PMID 16023586 DOI: 10.1016/J.Nbd.2005.01.020  0.383
2005 Yamashita T, Sawamoto K, Suzuki S, Suzuki N, Adachi K, Kawase T, Mihara M, Ohsugi Y, Abe K, Okano H. Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons. Journal of Neurochemistry. 94: 459-68. PMID 15998296 DOI: 10.1111/J.1471-4159.2005.03227.X  0.649
2005 Nakamura M, Okano H, Toyama Y, Dai HN, Finn TP, Bregman BS. Transplantation of embryonic spinal cord-derived neurospheres support growth of supraspinal projections and functional recovery after spinal cord injury in the neonatal rat Journal of Neuroscience Research. 81: 457-468. PMID 15968644 DOI: 10.1002/Jnr.20580  0.311
2005 Hishikawa K, Marumo T, Miura S, Nakanishi A, Matsuzaki Y, Shibata K, Ichiyanagi T, Kohike H, Komori T, Takahashi I, Takase O, Imai N, Yoshikawa M, Inowa T, Hayashi M, ... ... Okano H, et al. Musculin/MyoR is expressed in kidney side population cells and can regulate their function. The Journal of Cell Biology. 169: 921-8. PMID 15967813 DOI: 10.1083/Jcb.200412167  0.349
2005 Islam MO, Kanemura Y, Tajria J, Mori H, Kobayashi S, Shofuda T, Miyake J, Hara M, Yamasaki M, Okano H. Characterization of ABC transporter ABCB1 expressed in human neural stem/progenitor cells. Febs Letters. 579: 3473-80. PMID 15950972 DOI: 10.1016/J.Febslet.2005.05.019  0.392
2005 Sahara M, Sata M, Matsuzaki Y, Tanaka K, Morita T, Hirata Y, Okano H, Nagai R. Comparison of various bone marrow fractions in the ability to participate in vascular remodeling after mechanical injury. Stem Cells (Dayton, Ohio). 23: 874-8. PMID 15941860 DOI: 10.1634/Stemcells.2005-0012  0.348
2005 Matsumoto T, Okamoto R, Yajima T, Mori T, Okamoto S, Ikeda Y, Mukai M, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, et al. Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine. Gastroenterology. 128: 1851-67. PMID 15940621 DOI: 10.1053/J.Gastro.2005.03.085  0.34
2005 Jomphe C, Bourque MJ, Fortin GD, St-Gelais F, Okano H, Kobayashi K, Trudeau LE. Use of TH-EGFP transgenic mice as a source of identified dopaminergic neurons for physiological studies in postnatal cell culture. Journal of Neuroscience Methods. 146: 1-12. PMID 15935217 DOI: 10.1016/J.Jneumeth.2005.01.014  0.373
2005 Matsuda Y, Wakamatsu Y, Kohyama J, Okano H, Fukuda K, Yasugi S. Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development. Development (Cambridge, England). 132: 2783-93. PMID 15930109 DOI: 10.1242/Dev.01853  0.398
2005 Uchida K, Momiyama T, Okano H, Yuzaki M, Koizumi A, Mine Y, Kawase T. Potential functional neural repair with grafted neural stem cells of early embryonic neuroepithelial origin. Neuroscience Research. 52: 276-86. PMID 15927727 DOI: 10.1016/J.Neures.2005.03.015  0.418
2005 Okano H, Kawahara H, Toriya M, Nakao K, Shibata S, Imai T. Function of RNA-binding protein Musashi-1 in stem cells. Experimental Cell Research. 306: 349-56. PMID 15925591 DOI: 10.1016/J.Yexcr.2005.02.021  0.424
2005 Yoshimi K, Ren YR, Seki T, Yamada M, Ooizumi H, Onodera M, Saito Y, Murayama S, Okano H, Mizuno Y, Mochizuki H. Possibility for neurogenesis in substantia nigra of parkinsonian brain. Annals of Neurology. 58: 31-40. PMID 15912513 DOI: 10.1002/Ana.20506  0.366
2005 Yuasa S, Itabashi Y, Koshimizu U, Tanaka T, Sugimura K, Kinoshita M, Hattori F, Fukami S, Shimazaki T, Ogawa S, Okano H, Fukuda K. Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nature Biotechnology. 23: 607-11. PMID 15867910 DOI: 10.1038/Nbt1093  0.39
2005 Islam MO, Kanemura Y, Tajria J, Mori H, Kobayashi S, Hara M, Yamasaki M, Okano H, Miyake J. Functional expression of ABCG2 transporter in human neural stem/progenitor cells. Neuroscience Research. 52: 75-82. PMID 15811555 DOI: 10.1016/J.Neures.2005.01.013  0.42
2005 Nakamura Y, Yamamoto M, Oda E, Kanemura Y, Kodama E, Yamamoto A, Yamamoto H, Miyado K, Okano HJ, Fukagawa R, Higaki K, Yamasaki M, Okano H. A novel marker for Purkinje cells, KIAA0864 protein. An analysis based on a monoclonal antibody HFB-16 in developing human cerebellum. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 423-30. PMID 15805417 DOI: 10.1369/Jhc.4A6499.2005  0.334
2005 Kambara H, Okano H, Chiocca EA, Saeki Y. An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor. Cancer Research. 65: 2832-9. PMID 15805284 DOI: 10.1158/0008-5472.Can-04-3227  0.339
2005 Nagato M, Heike T, Kato T, Yamanaka Y, Yoshimoto M, Shimazaki T, Okano H, Nakahata T. Prospective characterization of neural stem cells by flow cytometry analysis using a combination of surface markers. Journal of Neuroscience Research. 80: 456-66. PMID 15795928 DOI: 10.1002/Jnr.20442  0.433
2005 Yoda A, Kouike H, Okano H, Sawa H. Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans. Development (Cambridge, England). 132: 1885-93. PMID 15790964 DOI: 10.1242/Dev.01776  0.382
2005 Iwanami A, Kaneko S, Nakamura M, Kanemura Y, Mori H, Kobayashi S, Yamasaki M, Momoshima S, Ishii H, Ando K, Tanioka Y, Tamaoki N, Nomura T, Toyama Y, Okano H. Transplantation of human neural stem cells for spinal cord injury in primates Journal of Neuroscience Research. 80: 182-190. PMID 15772979 DOI: 10.1002/Jnr.20436  0.316
2005 Akamatsu W, Fujihara H, Mitsuhashi T, Yano M, Shibata S, Hayakawa Y, Okano HJ, Sakakibara S, Takano H, Takano T, Takahashi T, Noda T, Okano H. The RNA-binding protein HuD regulates neuronal cell identity and maturation. Proceedings of the National Academy of Sciences of the United States of America. 102: 4625-30. PMID 15764704 DOI: 10.1073/Pnas.0407523102  0.445
2005 Pignatelli A, Kobayashi K, Okano H, Belluzzi O. Functional properties of dopaminergic neurones in the mouse olfactory bulb. The Journal of Physiology. 564: 501-14. PMID 15731185 DOI: 10.1113/Jphysiol.2005.084632  0.35
2005 Suzuki S, Yamashita T, Tanaka K, Hattori H, Sawamoto K, Okano H, Suzuki N. Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 685-93. PMID 15716858 DOI: 10.1038/Sj.Jcbfm.9600061  0.657
2005 Kitagawa A, Nakayama T, Takenaga M, Matsumoto K, Tokura Y, Ohta Y, Ichinohe M, Yamaguchi Y, Suzuki N, Okano H, Igarashi R. Lecithinized brain-derived neurotrophic factor promotes the differentiation of embryonic stem cells in vitro and in vivo. Biochemical and Biophysical Research Communications. 328: 1051-7. PMID 15707984 DOI: 10.1016/J.Bbrc.2005.01.063  0.371
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