| Year |
Citation |
Score |
| 2022 |
Branche E, Wang YT, Viramontes KM, Valls Cuevas JM, Xie J, Ana-Sosa-Batiz F, Shafee N, Duttke SH, McMillan RE, Clark AE, Nguyen MN, Garretson AF, Crames JJ, Spann NJ, Zhu Z, ... ... Spector DH, et al. SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus. Nature Communications. 13: 5341. PMID 36097162 DOI: 10.1038/s41467-022-33041-1 |
0.403 |
|
| 2020 |
Clark AE, Zhu Z, Krach F, Rich JN, Yeo GW, Spector DH. Zika virus is transmitted in neural progenitor cells via cell-to-cell spread and infection is inhibited by the autophagy inducer trehalose. Journal of Virology. PMID 33328307 DOI: 10.1128/JVI.02024-20 |
0.383 |
|
| 2019 |
Bernstein DI, Morello CS, Cardin RD, Bravo FJ, Kraynyak KA, Spector DH. A vaccine containing highly purified virus particles in adjuvant provides high level protection against genital infection and disease in guinea pigs challenged intravaginally with homologous and heterologous strains of herpes simplex virus type 2. Vaccine. PMID 31611098 DOI: 10.1016/J.Vaccine.2019.09.090 |
0.355 |
|
| 2017 |
Clark AE, Sabalza M, Gordts PLSM, Spector DH. Human Cytomegalovirus Replication is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 Through Distinctively Different Mechanisms. Journal of Virology. PMID 29237845 DOI: 10.1128/Jvi.02015-17 |
0.43 |
|
| 2016 |
Batra R, Stark TJ, Clark E, Belzile JP, Wheeler EC, Yee BA, Huang H, Gelboin-Burkhart C, Huelga SC, Aigner S, Roberts BT, Bos TJ, Sathe S, Donohue JP, Rigo F, ... ... Spector DH, et al. RNA-binding protein CPEB1 remodels host and viral RNA landscapes. Nature Structural & Molecular Biology. PMID 27775709 DOI: 10.1038/Nsmb.3310 |
0.522 |
|
| 2015 |
Belzile JP, Sabalza M, Craig M, Clark E, Morello CS, Spector DH. Trehalose, an mTOR-Independent Inducer of Autophagy, Inhibits Human Cytomegalovirus Infection in Multiple Cell Types. Journal of Virology. PMID 26559848 DOI: 10.1128/Jvi.02651-15 |
0.484 |
|
| 2015 |
Clark E, Spector DH. Studies on the Contribution of Human Cytomegalovirus UL21a and UL97 to Viral Growth and Inactivation of the Anaphase-Promoting Complex/Cyclosome (APC/C) E3 Ubiquitin Ligase Reveal a Unique Cellular Mechanism for Downmodulation of the APC/C Subunits APC1, APC4, and APC5. Journal of Virology. 89: 6928-39. PMID 25903336 DOI: 10.1128/Jvi.00403-15 |
0.412 |
|
| 2015 |
Spector DH. Human cytomegalovirus riding the cell cycle. Medical Microbiology and Immunology. 204: 409-19. PMID 25776080 DOI: 10.1007/S00430-015-0396-Z |
0.501 |
|
| 2014 |
Spector DH. IUGR and congenital cytomegalovirus infection. The Journal of Infectious Diseases. 209: 1497-9. PMID 24526739 DOI: 10.1093/Infdis/Jiu092 |
0.402 |
|
| 2014 |
Belzile JP, Stark TJ, Yeo GW, Spector DH. Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA. Journal of Virology. 88: 4021-39. PMID 24453373 DOI: 10.1128/Jvi.03492-13 |
0.465 |
|
| 2013 |
Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, ... ... Spector DH, et al. 25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. The Journal of Biological Chemistry. 288: 35812-23. PMID 24189069 DOI: 10.1074/Jbc.M113.519637 |
0.312 |
|
| 2012 |
DuRose JB, Li J, Chien S, Spector DH. Infection of vascular endothelial cells with human cytomegalovirus under fluid shear stress reveals preferential entry and spread of virus in flow conditions simulating atheroprone regions of the artery. Journal of Virology. 86: 13745-55. PMID 23055562 DOI: 10.1128/Jvi.02244-12 |
0.344 |
|
| 2012 |
Morello CS, Kraynyak KA, Levinson MS, Chen Z, Lee KF, Spector DH. Inactivated HSV-2 in MPL/alum adjuvant provides nearly complete protection against genital infection and shedding following long term challenge and rechallenge. Vaccine. 30: 6541-50. PMID 22947141 DOI: 10.1016/J.Vaccine.2012.08.049 |
0.372 |
|
| 2012 |
Strang BL, Bender BJ, Sharma M, Pesola JM, Sanders RL, Spector DH, Coen DM. A mutation deleting sequences encoding the amino terminus of human cytomegalovirus UL84 impairs interaction with UL44 and capsid localization. Journal of Virology. 86: 11066-77. PMID 22855486 DOI: 10.1128/Jvi.01379-12 |
0.544 |
|
| 2012 |
Steininger C, Widhopf GF, Ghia EM, Morello CS, Vanura K, Sanders R, Spector D, Guiney D, Jäger U, Kipps TJ. Recombinant antibodies encoded by IGHV1-69 react with pUL32, a phosphoprotein of cytomegalovirus and B-cell superantigen. Blood. 119: 2293-301. PMID 22234695 DOI: 10.1182/Blood-2011-08-374058 |
0.382 |
|
| 2012 |
Stark TJ, Arnold JD, Spector DH, Yeo GW. High-resolution profiling and analysis of viral and host small RNAs during human cytomegalovirus infection. Journal of Virology. 86: 226-35. PMID 22013051 DOI: 10.1128/Jvi.05903-11 |
0.325 |
|
| 2011 |
Burgdorf SW, Clark CL, Burgdorf JR, Spector DH. Mutation of glutamine to arginine at position 548 of IE2 86 in human cytomegalovirus leads to decreased expression of IE2 40, IE2 60, UL83, and UL84 and increased transcription of US8-9 and US29-32. Journal of Virology. 85: 11098-110. PMID 21865379 DOI: 10.1128/Jvi.05315-11 |
0.757 |
|
| 2011 |
Morello CS, Levinson MS, Kraynyak KA, Spector DH. Immunization with herpes simplex virus 2 (HSV-2) genes plus inactivated HSV-2 is highly protective against acute and recurrent HSV-2 disease. Journal of Virology. 85: 3461-72. PMID 21270160 DOI: 10.1128/Jvi.02521-10 |
0.333 |
|
| 2010 |
Tran K, Kamil JP, Coen DM, Spector DH. Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1. Journal of Virology. 84: 10832-43. PMID 20686030 DOI: 10.1128/Jvi.01260-10 |
0.737 |
|
| 2010 |
Sanders RL, Spector DH. Human cytomegalovirus IE2 86 and IE2 40 proteins differentially regulate UL84 protein expression posttranscriptionally in the absence of other viral gene products. Journal of Virology. 84: 5158-70. PMID 20200242 DOI: 10.1128/Jvi.00090-10 |
0.493 |
|
| 2010 |
Tran K, Mahr JA, Spector DH. Proteasome subunits relocalize during human cytomegalovirus infection, and proteasome activity is necessary for efficient viral gene transcription. Journal of Virology. 84: 3079-93. PMID 20042513 DOI: 10.1128/Jvi.02236-09 |
0.735 |
|
| 2009 |
Kapasi AJ, Clark CL, Tran K, Spector DH. Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription. Journal of Virology. 83: 5904-17. PMID 19297489 DOI: 10.1128/Jvi.02651-08 |
0.803 |
|
| 2008 |
Sanders RL, Del Rosario CJ, White EA, Spector DH. Internal deletions of IE2 86 and loss of the late IE2 60 and IE2 40 proteins encoded by human cytomegalovirus affect the levels of UL84 protein but not the amount of UL84 mRNA or the loading and distribution of the mRNA on polysomes. Journal of Virology. 82: 11383-97. PMID 18787008 DOI: 10.1128/Jvi.01293-08 |
0.698 |
|
| 2008 |
Sanchez V, Spector DH. Subversion of cell cycle regulatory pathways Current Topics in Microbiology and Immunology. 325: 243-262. PMID 18637510 DOI: 10.1007/978-3-540-77349-8_14 |
0.471 |
|
| 2008 |
Sanders RL, Clark CL, Morello CS, Spector DH. Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses. Journal of Virology. 82: 7059-77. PMID 18463148 DOI: 10.1128/Jvi.00675-08 |
0.542 |
|
| 2008 |
Tran K, Mahr JA, Choi J, Teodoro JG, Green MR, Spector DH. Accumulation of substrates of the anaphase-promoting complex (APC) during human cytomegalovirus infection is associated with the phosphorylation of Cdh1 and the dissociation and relocalization of APC subunits. Journal of Virology. 82: 529-37. PMID 17942546 DOI: 10.1128/Jvi.02010-07 |
0.689 |
|
| 2008 |
Kapasi AJ, Spector DH. Inhibition of the cyclin-dependent kinases at the beginning of human cytomegalovirus infection specifically alters the levels and localization of the RNA polymerase II carboxyl-terminal domain kinases cdk9 and cdk7 at the viral transcriptosome. Journal of Virology. 82: 394-407. PMID 17942543 DOI: 10.1128/Jvi.01681-07 |
0.802 |
|
| 2007 |
Grey F, Meyers H, White EA, Spector DH, Nelson J. A human cytomegalovirus-encoded microRNA regulates expression of multiple viral genes involved in replication. Plos Pathogens. 3: e163. PMID 17983268 DOI: 10.1371/Journal.Ppat.0030163 |
0.579 |
|
| 2007 |
Sanchez V, Mahr JA, Orazio NI, Spector DH. Nuclear export of the human cytomegalovirus tegument protein pp65 requires cyclin-dependent kinase activity and the Crm1 exporter. Journal of Virology. 81: 11730-6. PMID 17715235 DOI: 10.1128/Jvi.02760-06 |
0.495 |
|
| 2007 |
Morello CS, Kelley LA, Munks MW, Hill AB, Spector DH. DNA immunization using highly conserved murine cytomegalovirus genes encoding homologs of human cytomegalovirus UL54 (DNA polymerase) and UL105 (helicase) elicits strong CD8 T-cell responses and is protective against systemic challenge. Journal of Virology. 81: 7766-75. PMID 17507492 DOI: 10.1128/Jvi.00633-07 |
0.414 |
|
| 2007 |
White EA, Del Rosario CJ, Sanders RL, Spector DH. The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus. Journal of Virology. 81: 2573-83. PMID 17202222 DOI: 10.1128/Jvi.02454-06 |
0.702 |
|
| 2007 |
White EA, Spector DH. Early CMV gene expression and function Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. 264-294. DOI: 10.1017/CBO9780511545313.019 |
0.63 |
|
| 2006 |
Shlapobersky M, Sanders R, Clark C, Spector DH. Repression of HMGA2 gene expression by human cytomegalovirus involves the IE2 86-kilodalton protein and is necessary for efficient viral replication and inhibition of cyclin A transcription. Journal of Virology. 80: 9951-61. PMID 17005673 DOI: 10.1128/Jvi.01300-06 |
0.6 |
|
| 2006 |
Sanchez V, Spector DH. Cyclin-dependent kinase activity is required for efficient expression and posttranslational modification of human cytomegalovirus proteins and for production of extracellular particles. Journal of Virology. 80: 5886-96. PMID 16731927 DOI: 10.1128/Jvi.02656-05 |
0.579 |
|
| 2006 |
Munks MW, Gold MC, Zajac AL, Doom CM, Morello CS, Spector DH, Hill AB. Genome-wide analysis reveals a highly diverse CD8 T cell response to murine cytomegalovirus. Journal of Immunology (Baltimore, Md. : 1950). 176: 3760-6. PMID 16517745 DOI: 10.4049/Jimmunol.176.6.3760 |
0.382 |
|
| 2005 |
Tamrakar S, Kapasi AJ, Spector DH. Human cytomegalovirus infection induces specific hyperphosphorylation of the carboxyl-terminal domain of the large subunit of RNA polymerase II that is associated with changes in the abundance, activity, and localization of cdk9 and cdk7. Journal of Virology. 79: 15477-93. PMID 16306619 DOI: 10.1128/Jvi.79.24.15477-15493.2005 |
0.791 |
|
| 2005 |
White EA, Spector DH. Exon 3 of the human cytomegalovirus major immediate-early region is required for efficient viral gene expression and for cellular cyclin modulation. Journal of Virology. 79: 7438-52. PMID 15919900 DOI: 10.1128/Jvi.79.12.7438-7452.2005 |
0.715 |
|
| 2005 |
Morello CS, Ye M, Hung S, Kelley LA, Spector DH. Systemic priming-boosting immunization with a trivalent plasmid DNA and inactivated murine cytomegalovirus (MCMV) vaccine provides long-term protection against viral replication following systemic or mucosal MCMV challenge. Journal of Virology. 79: 159-75. PMID 15596812 DOI: 10.1128/Jvi.79.1.159-175.2005 |
0.33 |
|
| 2004 |
Ye M, Morello CS, Spector DH. Multiple epitopes in the murine cytomegalovirus early gene product M84 are efficiently presented in infected primary macrophages and contribute to strong CD8+-T-lymphocyte responses and protection following DNA immunization. Journal of Virology. 78: 11233-45. PMID 15452242 DOI: 10.1128/Jvi.78.20.11233-11245.2004 |
0.36 |
|
| 2004 |
Sanchez V, McElroy AK, Yen J, Tamrakar S, Clark CL, Schwartz RA, Spector DH. Cyclin-dependent kinase activity is required at early times for accurate processing and accumulation of the human cytomegalovirus UL122-123 and UL37 immediate-early transcripts and at later times for virus production. Journal of Virology. 78: 11219-32. PMID 15452241 DOI: 10.1128/Jvi.78.20.11219-11232.2004 |
0.765 |
|
| 2004 |
White EA, Clark CL, Sanchez V, Spector DH. Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression. Journal of Virology. 78: 1817-30. PMID 14747546 DOI: 10.1128/Jvi.78.4.1817-1830.2004 |
0.683 |
|
| 2003 |
Sanchez V, McElroy AK, Spector DH. Mechanisms governing maintenance of Cdk1/cyclin B1 kinase activity in cells infected with human cytomegalovirus. Journal of Virology. 77: 13214-24. PMID 14645578 DOI: 10.1128/Jvi.77.24.13214-13224.2003 |
0.718 |
|
| 2003 |
Biswas N, Sanchez V, Spector DH. Human cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication. Journal of Virology. 77: 2369-76. PMID 12551974 DOI: 10.1128/Jvi.77.4.2369-2376.2003 |
0.564 |
|
| 2003 |
Fortunato EA, Spector DH. Viral induction of site-specific chromosome damage. Reviews in Medical Virology. 13: 21-37. PMID 12516060 DOI: 10.1002/Rmv.368 |
0.518 |
|
| 2002 |
Sanchez V, Spector DH. Virology. CMV makes a timely exit. Science (New York, N.Y.). 297: 778-9. PMID 12161637 DOI: 10.1126/Science.1075102 |
0.336 |
|
| 2002 |
Fortunato EA, Sanchez V, Yen JY, Spector DH. Infection of cells with human cytomegalovirus during S phase results in a blockade to immediate-early gene expression that can be overcome by inhibition of the proteasome. Journal of Virology. 76: 5369-79. PMID 11991965 DOI: 10.1128/Jvi.76.11.5369-5379.2002 |
0.468 |
|
| 2002 |
Morello CS, Ye M, Spector DH. Development of a vaccine against murine cytomegalovirus (MCMV), consisting of plasmid DNA and formalin-inactivated MCMV, that provides long-term, complete protection against viral replication. Journal of Virology. 76: 4822-35. PMID 11967299 DOI: 10.1128/Jvi.76.10.4822-4835.2002 |
0.365 |
|
| 2002 |
Sanchez V, Clark CL, Yen JY, Dwarakanath R, Spector DH. Viable human cytomegalovirus recombinant virus with an internal deletion of the IE2 86 gene affects late stages of viral replication. Journal of Virology. 76: 2973-89. PMID 11861863 DOI: 10.1128/Jvi.76.6.2973-2989.2002 |
0.544 |
|
| 2002 |
Ye M, Morello CS, Spector DH. Strong CD8 T-cell responses following coimmunization with plasmids expressing the dominant pp89 and subdominant M84 antigens of murine cytomegalovirus correlate with long-term protection against subsequent viral challenge. Journal of Virology. 76: 2100-12. PMID 11836387 DOI: 10.1128/Jvi.76.5.2100-2112.2002 |
0.358 |
|
| 2001 |
Dwarakanath RS, Clark CL, McElroy AK, Spector DH. The use of recombinant baculoviruses for sustained expression of human cytomegalovirus immediate early proteins in fibroblasts. Virology. 284: 297-307. PMID 11384228 DOI: 10.1006/Viro.2001.0924 |
0.722 |
|
| 2000 |
McElroy AK, Dwarakanath RS, Spector DH. Dysregulation of cyclin E gene expression in human cytomegalovirus-infected cells requires viral early gene expression and is associated with changes in the Rb-related protein p130. Journal of Virology. 74: 4192-206. PMID 10756032 DOI: 10.1128/Jvi.74.9.4192-4206.2000 |
0.747 |
|
| 2000 |
Morello CS, Cranmer LD, Spector DH. Suppression of murine cytomegalovirus (MCMV) replication with a DNA vaccine encoding MCMV M84 (a homolog of human cytomegalovirus pp65) Journal of Virology. 74: 3696-3708. PMID 10729145 DOI: 10.1128/Jvi.74.8.3696-3708.2000 |
0.38 |
|
| 2000 |
Fortunato EA, McElroy AK, Sanchez I, Spector DH. Exploitation of cellular signaling and regulatory pathways by human cytomegalovirus. Trends in Microbiology. 8: 111-9. PMID 10707064 DOI: 10.1016/S0966-842X(00)01699-1 |
0.674 |
|
| 2000 |
Fortunato EA, Dell'Aquila ML, Spector DH. Specific chromosome I breaks induced by human cytomegalovirus Proceedings of the National Academy of Sciences of the United States of America. 97: 853-858. PMID 10639169 DOI: 10.1073/Pnas.97.2.853 |
0.484 |
|
| 1999 |
Fortunato EA, Spector DH. Regulation of human cytomegalovirus gene expression Advances in Virus Research. 54: 61-128. PMID 10547675 DOI: 10.1016/S0065-3527(08)60366-8 |
0.565 |
|
| 1999 |
Morello CS, Cranmer LD, Spector DH. In vivo replication, latency, and immunogenicity of murine cytomegalovirus mutants with deletions in the M83 and M84 genes, the putative homologs of human cytomegalovirus pp65 (UL83) Journal of Virology. 73: 7678-7693. PMID 10438858 DOI: 10.1128/Jvi.73.9.7678-7693.1999 |
0.407 |
|
| 1999 |
Spector D, Fortunato E. Influence of the cell cycle on the initiation of the HCMV infection — How the virus beats the clock Journal of Clinical Virology. 12: 90. DOI: 10.1016/S1386-6532(99)90394-3 |
0.372 |
|
| 1998 |
Rodems SM, Spector DH. Extracellular signal-regulated kinase activity is sustained early during human cytomegalovirus infection Journal of Virology. 72: 9173-9180. PMID 9765464 DOI: 10.1128/Jvi.72.11.9173-9180.1998 |
0.534 |
|
| 1998 |
Navarro L, Mowen K, Rodems S, Weaver B, Reich N, Spector D, David M. Cytomegalovirus activates interferon immediate-early response gene expression and an interferon regulatory factor 3-containing interferon-stimulated response element-binding complex. Molecular and Cellular Biology. 18: 3796-802. PMID 9632763 DOI: 10.1128/Mcb.18.7.3796 |
0.455 |
|
| 1998 |
Salvant BS, Fortunato EA, Spector DH. Cell cycle dysregulation by human cytomegalovirus: Influence of the cell cycle phase at the time of infection and effects on cyclin transcription Journal of Virology. 72: 3729-3741. PMID 9557655 DOI: 10.1128/Jvi.72.5.3729-3741.1998 |
0.51 |
|
| 1998 |
Rodems SM, Clark CL, Spector DH. Separate DNA elements containing ATF/CREB and IE86 binding sites differentially regulate the human cytomegalovirus UL112-113 promoter at early and late times in the infection Journal of Virology. 72: 2697-2707. PMID 9525587 DOI: 10.1128/Jvi.72.4.2697-2707.1998 |
0.454 |
|
| 1998 |
Fortunato EA, Spector DH. p53 and RPA are sequestered in viral replication centers in the nuclei of cells infected with human cytomegalovirus Journal of Virology. 72: 2033-2039. PMID 9499057 DOI: 10.1128/Jvi.72.3.2033-2039.1998 |
0.494 |
|
| 1997 |
Hsia K, Spector DH, Spector SA. Molecular analysis of the differential restriction of human immunodeficiency virus type 1 replication in neuronal cell lines Journal of General Virology. 78: 3255-3264. PMID 9400976 DOI: 10.1099/0022-1317-78-12-3255 |
0.386 |
|
| 1997 |
Fortunato EA, Sommer MH, Yoder K, Spector DH. Identification of domains within the human cytomegalovirus major immediate-early 86-kilodalton protein and the retinoblastoma protein required for physical and functional interaction with each other Journal of Virology. 71: 8176-8185. PMID 9343168 DOI: 10.1128/Jvi.71.11.8176-8185.1997 |
0.708 |
|
| 1997 |
Moreno TN, Fortunato EA, Hsia K, Spector SA, Spector DH. A model system for human Cytomegalovirus-mediated modulation of human immunodeficiency virus type 1 long terminal repeat activity in brain cells Journal of Virology. 71: 3693-3701. PMID 9094643 DOI: 10.1128/Jvi.71.5.3693-3701.1997 |
0.416 |
|
| 1996 |
Spector DH. Activation and regulation of human cytomegalovirus early genes Intervirology. 39: 361-377. PMID 9130046 DOI: 10.1159/000150507 |
0.496 |
|
| 1996 |
Cranmer LD, Clark CL, Morello CS, Farrell HE, Rawlinson WD, Spector DH. Identification, analysis, and evolutionary relationships of the putative murine cytomegalovirus homologs of the human cytomegalovirus UL82 (pp71) and UL83 (pp65) matrix phosphoproteins Journal of Virology. 70: 7929-7939. PMID 8892916 DOI: 10.1128/Jvi.70.11.7929-7939.1996 |
0.397 |
|
| 1996 |
González Armas JC, Morello CS, Cranmer LD, Spector DH. DNA immunization confers protection against murine cytomegalovirus infection Journal of Virology. 70: 7921-7928. PMID 8892915 DOI: 10.1128/Jvi.70.11.7921-7928.1996 |
0.304 |
|
| 1996 |
Schwartz R, Helmich B, Spector DH. CREB and CREB-binding proteins play an important role in the IE2 86- kilodalton protein-mediated transactivation of the human cytomegalovirus 2.2- kilobase RNA promoter Journal of Virology. 70: 6955-6966. PMID 8794339 DOI: 10.1128/Jvi.70.10.6955-6966.1996 |
0.454 |
|
| 1995 |
Koval V, Jault FM, Pal PG, Moreno TN, Aiken C, Trono D, Spector SA, Spector DH. Differential effects of human cytomegalovirus on integrated and unintegrated human immunodeficiency virus sequences Journal of Virology. 69: 1645-1651. PMID 7853500 DOI: 10.1128/Jvi.69.3.1645-1651.1995 |
0.329 |
|
| 1995 |
Scully AL, Sommer MH, Schwartz R, Spector DH. The human cytomegalovirus IE2 86-kilodalton protein interacts with an early gene promoter via site-specific DNA binding and protein-protein associations Journal of Virology. 69: 6533-6540. PMID 7666555 DOI: 10.1128/Jvi.69.10.6533-6540.1995 |
0.444 |
|
| 1995 |
Jault FM, Jault JM, Ruchti F, Fortunato EA, Clark C, Corbeil J, Richman DD, Spector DH. Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest Journal of Virology. 69: 6697-6704. PMID 7474079 DOI: 10.1128/Jvi.69.11.6697-6704.1995 |
0.515 |
|
| 1995 |
Jault FM, Jault JM, Ruchti F, Fortunato EA, Clark C, Corbeil J, Richman DD, Spector DH. Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest. Journal of Virology. 69: 6697-6704. DOI: 10.1128/jvi.69.11.6697-6704.1995 |
0.326 |
|
| 1994 |
Jault FM, Spector SA, Spector DH. The effects of cytomegalovirus on human immunodeficiency virus replication in brain-derived cells correlate with permissiveness of the cells for each virus Journal of Virology. 68: 959-973. PMID 8289398 DOI: 10.1128/Jvi.68.2.959-973.1994 |
0.396 |
|
| 1994 |
Lathey JL, Spector DH, Spector SA. Human Cytomegalovirus-Mediated Enhancement of Human Immunodeficiency Virus Type-1 Production in Monocyte-Derived Macrophages Virology. 199: 98-104. PMID 8116259 DOI: 10.1006/Viro.1994.1101 |
0.361 |
|
| 1994 |
Wade EJ, Spector DH. The human cytomegalovirus origin of DNA replication (oriLyt) is the critical cis-acting sequence regulating replication-dependent late induction of the viral 1.2-Kilobase RNA promoter Journal of Virology. 68: 6567-6577. PMID 8083993 DOI: 10.1128/Jvi.68.10.6567-6577.1994 |
0.49 |
|
| 1994 |
Sommer MH, Scully AL, Spector DH. Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein Journal of Virology. 68: 6223-6231. PMID 8083962 DOI: 10.1128/Jvi.68.10.6223-6231.1994 |
0.433 |
|
| 1994 |
Schwartz R, Sommer MH, Scully A, Spector DH. Site-specific binding of the human cytomegalovirus IE2 86-kilodalton protein to an early gene promoter Journal of Virology. 68: 5613-5622. PMID 8057441 DOI: 10.1128/Jvi.68.9.5613-5622.1994 |
0.413 |
|
| 1994 |
Cranmer LD, Clark C, Spector DH. Cloning, Characterization, and Expression of the Murine Cytomegalovirus Homologue of the Human Cytomegalovirus 28-kDa Matrix Phosphoprotein (UL99) Virology. 205: 417-429. PMID 7975245 DOI: 10.1006/Viro.1994.1662 |
0.508 |
|
| 1993 |
Klucher KM, Sommer M, Kadonaga JT, Spector DH. In vivo and in vitro analysis of transcriptional activation mediated by the human cytomegalovirus major immediate-early proteins. Molecular and Cellular Biology. 13: 1238-50. PMID 8423789 DOI: 10.1128/Mcb.13.2.1238 |
0.43 |
|
| 1992 |
Wade EJ, Klucher KM, Spector DH. An AP-1 binding site is the predominant cis-acting regulatory element in the 1.2-kilobase early RNA promoter of human cytomegalovirus Journal of Virology. 66: 2407-2417. PMID 1312636 DOI: 10.1128/Jvi.66.4.2407-2417.1992 |
0.499 |
|
| 1991 |
Mosier DE, Gulizia RJ, Baird SM, Wilson DB, Spector DH, Spector SA. Human immunodeficiency virus infection of human-PBL-SCID mice Science. 251: 791-794. PMID 1990441 DOI: 10.1126/Science.1990441 |
0.403 |
|
| 1991 |
Elliott R, Clark C, Jaquish D, Spector DH. Transcription analysis and sequence of the putative murine cytomegalovirus DNA polymerase gene Virology. 185: 169-186. PMID 1718083 DOI: 10.1016/0042-6822(91)90765-4 |
0.432 |
|
| 1991 |
Koval V, Clark C, Vaishnav M, Spector SA, Spector DH. Human cytomegalovirus inhibits human immunodeficiency virus replication in cells productively infected by both viruses Journal of Virology. 65: 6969-6978. PMID 1658386 DOI: 10.1128/Jvi.65.12.6969-6978.1991 |
0.41 |
|
| 1990 |
Klucher KM, Spector DH. The human cytomegalovirus 2.7-kilobase RNA promoter contains a functional binding site for the adenovirus major late transcription factor Journal of Virology. 64: 4189-4198. PMID 2166813 DOI: 10.1128/Jvi.64.9.4189-4198.1990 |
0.415 |
|
| 1990 |
Spector DH, Klucher KM, Rabert DK, Wright DA. Human cytomegalovirus early gene expression Current Topics in Microbiology and Immunology. 154: 21-45. PMID 2161321 DOI: 10.1007/978-3-642-74980-3_2 |
0.427 |
|
| 1990 |
Spector DH, Wade E, Wright DA, Koval V, Clark C, Jaquish D, Spector SA. Human immunodeficiency virus pseudotypes with expanded cellular and species tropism Journal of Virology. 64: 2298-2308. PMID 1691314 DOI: 10.1128/Jvi.64.5.2298-2308.1990 |
0.409 |
|
| 1989 |
Klucher KM, Rabert DK, Spector DH. Sequences in the human cytomegalovirus 2.7-kilobase RNA promoter which mediate its regulation as an early gene Journal of Virology. 63: 5334-5343. PMID 2555558 DOI: 10.1128/Jvi.63.12.5334-5343.1989 |
0.534 |
|
| 1989 |
Mosier DE, Gulizia RJ, Baird SM, Spector S, Spector D, Kipps TJ, Fox RI, Carson DA, Cooper N, Richman DD. Studies of HIV infection and the development of Epstein-Barr virus-related B cell lymphomas following transfer of human lymphocytes to mice with severe combined immunodeficiency. Current Topics in Microbiology and Immunology. 152: 195-9. PMID 2553338 DOI: 10.1007/978-3-642-74974-2_23 |
0.384 |
|
| 1989 |
Hsia K, Spector DH, Lawrie J, Spector SA. Enzymatic amplification of human cytomegalovirus sequences by polymerase chain reaction Journal of Clinical Microbiology. 27: 1802-1809. PMID 2549097 DOI: 10.1128/Jcm.27.8.1802-1809.1989 |
0.352 |
|
| 1989 |
Spector SA, Hsia K, Denaro F, Spector DH. Use of molecular probes to detect human cytomegalovirus and human immunodeficiency virus Clinical Chemistry. 35: 1581-1587. PMID 2547533 DOI: 10.1093/Clinchem/35.8.1581 |
0.334 |
|
| 1989 |
Wright DA, Spector DH. Posttranscriptional regulation of the class of human cytomegalovirus phosphoproteins encoded by an early transcription unit Journal of Virology. 63: 3117-3127. PMID 2542619 DOI: 10.1128/Jvi.63.7.3117-3127.1989 |
0.487 |
|
| 1988 |
Staprans SI, Rabert DK, Spector DH. Identification of sequence requirements and trans-acting functions necessary for regulated expression of a human cytomegalovirus early gene Journal of Virology. 62: 3463-3473. PMID 2841497 DOI: 10.1128/Jvi.62.9.3463-3473.1988 |
0.499 |
|
| 1988 |
Mercer JA, Wiley CA, Spector DH. Pathogenesis of murine cytomegalovirus infection: identification of infected cells in the spleen during acute and latent infections. Journal of Virology. 62: 987-97. PMID 2828694 DOI: 10.1128/Jvi.62.3.987-997.1988 |
0.453 |
|
| 1988 |
Marks JR, Spector DH. Replication of the murine cytomegalovirus genome: Structure and role of the termini in the generation and cleavage of concatenates Virology. 162: 98-107. PMID 2827390 DOI: 10.1016/0042-6822(88)90398-4 |
0.362 |
|
| 1988 |
Wright DA, Staprans SI, Spector DH. Four phosphoproteins with common amino termini are encoded by human cytomegalovirus AD169 Journal of Virology. 62: 331-340. PMID 2824853 DOI: 10.1128/Jvi.62.1.331-340.1988 |
0.5 |
|
| 1986 |
Staprans SI, Spector DH. 2.2-Kilobase class of early transcripts encoded by cell-related sequences in human cytomegalovirus strain AD169 Journal of Virology. 57: 591-602. PMID 3003391 DOI: 10.1128/Jvi.57.2.591-602.1986 |
0.372 |
|
| 1986 |
Mercer JA, Spector DH. Pathogenesis of acute murine cytomegalovirus infection in resistant and suceptible strains of mice Journal of Virology. 57: 497-504. PMID 3003382 DOI: 10.1128/Jvi.57.2.497-504.1986 |
0.399 |
|
| 1985 |
Rasmussen RD, Staprans SI, Shaw SB, Spector DH. Sequences in human cytomegalovirus which hybridize with the avian retrovirus oncogene v-myc are G + C rich and do not hybridize with the human c-myc gene. Molecular and Cellular Biology. 5: 1525-30. PMID 2993868 DOI: 10.1128/Mcb.5.6.1525 |
0.32 |
|
| 1985 |
Spector SA, Spector DH. The use of DNA probes in studies of human cytomegalovirus Clinical Chemistry. 31: 1514-1520. PMID 2992841 DOI: 10.1093/Clinchem/31.9.1514 |
0.487 |
|
| 1985 |
Shaw SB, Rasmussen RD, McDonough SH, Staprans SI, Vacquier JP, Spector DH. Cell-related sequences in the DNA genome of human cytomegalovirus strain AD169. Journal of Virology. 55: 843-8. PMID 2991601 DOI: 10.1128/Jvi.55.3.843-848.1985 |
0.352 |
|
| 1985 |
McDonough SH, Staprans SI, Spector DH. Analysis of the major transcripts encoded by the long repeat of human cytomegalovirus strain AD169 Journal of Virology. 53: 711-718. PMID 2983083 DOI: 10.1128/Jvi.53.3.711-718.1985 |
0.37 |
|
| 1984 |
Tamashiro JC, Filpula D, Friedmann T, Spector DH. Structure of the heterogeneous L-S junction region of human cytomegalovirus strain AD169 DNA Journal of Virology. 52: 541-548. PMID 6092675 DOI: 10.1128/Jvi.52.2.541-548.1984 |
0.337 |
|
| 1984 |
Marks JR, Spector DH. Fusion of the termini of the murine cytomegalovirus genome after infection Journal of Virology. 52: 24-28. PMID 6090700 DOI: 10.1128/Jvi.52.1.24-28.1984 |
0.417 |
|
| 1983 |
Spector DH, Vacquier JP. Human cytomegalovirus (strain AD169) contains sequences related to the avian retrovirus oncogene v-myc Proceedings of the National Academy of Sciences of the United States of America. 80: 3889-3893. PMID 6306648 DOI: 10.1073/Pnas.80.13.3889 |
0.308 |
|
| 1983 |
Marks JR, Mercer JA, Spector DH. Transcription in mouse embryo cells permissively infected by murine cytomegalovirus Virology. 131: 247-254. PMID 6196913 DOI: 10.1016/0042-6822(83)90550-0 |
0.422 |
|
| 1983 |
McDonough SH, Spector DH. Transcription in human fibroblasts permissively infected by human cytomegalovirus strain AD169 Virology. 125: 31-46. PMID 6187127 DOI: 10.1016/0042-6822(83)90061-2 |
0.439 |
|
| 1982 |
Spector SA, Spector DH. Molecular epidemiology of cytomegalovirus infections in premature twin infants and their mother Pediatric Infectious Disease. 1: 405-409. PMID 6298754 DOI: 10.1097/00006454-198211000-00009 |
0.327 |
|
| 1982 |
Spector DH, Hock L, Tamashiro JC. Cleavage maps for human cytomegalovirus DNA strain AD169 for restriction endonucleases EcoRI, BglII, and HindIII Journal of Virology. 42: 558-582. PMID 6283173 DOI: 10.1128/Jvi.42.2.558-582.1982 |
0.302 |
|
| 1982 |
Tamashiro JC, Hock LJ, Spector DH. Construction of a cloned library of the EcoRI fragments from the human cytomegalovirus genome (Strain AD169) Journal of Virology. 42: 547-557. PMID 6283172 DOI: 10.1128/Jvi.42.2.547-557.1982 |
0.321 |
|
| 1981 |
Spector DH. Gene-specific probes for avian retroviruses Current Topics in Microbiology and Immunology. 91: 41-80. PMID 6273070 DOI: 10.1007/978-3-642-68058-8_3 |
0.471 |
|
| 1979 |
Hughes SH, Stubblefield E, Payvar F, Engel JD, Dodgson JB, Spector D, Cordell B, Schimke RT, Varmus HE. Gene localization by chromosome fractionation: globin genes are on at least two chromosomes and three estrogen-inducible genes are on three chromosomes. Proceedings of the National Academy of Sciences of the United States of America. 76: 1348-52. PMID 286316 DOI: 10.1073/Pnas.76.3.1348 |
0.324 |
|
| 1979 |
Hughes SH, Payvar F, Spector D, Schimke RT, Robinson HL, Payne GS, Bishop JM, Varmus HE. Heterogeneity of genetic loci in chickens: analysis of endogenous viral and nonviral genes by cleavage of DNA with restriction endonucleases. Cell. 18: 347-59. PMID 227605 DOI: 10.1016/0092-8674(79)90054-0 |
0.432 |
|
| 1978 |
Hughes SH, Shank PR, Spector DH, Kung HJ, Bishop JM, Varmus HE, Vogt PK, Breitman ML. Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites. Cell. 15: 1397-410. PMID 215325 DOI: 10.1016/0092-8674(78)90064-8 |
0.352 |
|
| 1978 |
Spector DH, Varmus HE, Bishop JM. Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates. Proceedings of the National Academy of Sciences of the United States of America. 75: 4102-6. PMID 212733 DOI: 10.1073/Pnas.75.9.4102 |
0.315 |
|
| 1978 |
Spector DH, Baker B, Varmus HE, Bishop JM. Characteristics of cellular RNA related to the transforming gene of avian sarcoma viruses. Cell. 13: 381-6. PMID 203405 DOI: 10.1016/0092-8674(78)90206-4 |
0.357 |
|
| 1978 |
Spector DH, Smith K, Padgett T, McCombe P, Roulland-Dussoix D, Moscovici C, Varmus HE, Bishop JM. Uninfected avian cells contain RNA related to the transforming gene of avian sarcoma viruses. Cell. 13: 371-9. PMID 203404 DOI: 10.1016/0092-8674(78)90205-2 |
0.431 |
|
| 1977 |
Krzyzek RA, Lau AF, Faras AJ, Spector DH. Post-transcriptional control of avian oncornavirus transforming gene sequences in mammalian cells Nature. 269: 175-179. PMID 198665 DOI: 10.1038/269175A0 |
0.452 |
|
| 1975 |
Spector DH, Baltimore D. Polyadenylic acid on poliovirus RNA. IV. Poly(U) in replicative intermediate and double-stranded RNA Virology. 67: 498-505. PMID 171838 DOI: 10.1016/0042-6822(75)90450-X |
0.336 |
|
| 1975 |
Spector DH, Baltimore D. Poly(A) on mengovirus RNA Journal of Virology. 16: 1081-1084. PMID 170414 DOI: 10.1128/Jvi.16.4.1081-1084.1975 |
0.314 |
|
| 1975 |
Spector DH, Villa-Komaroff L, Baltimore D. Studies on the function of polyadenylic acid on poliovirus RNA Cell. 6: 41-44. PMID 170001 DOI: 10.1016/0092-8674(75)90071-9 |
0.348 |
|
| 1975 |
Spector DH, Baltimore D. Polyadenylic acid on poliovirus RNA. III. In vitro addition of polyadenylic acid to poliovirus RNAs Journal of Virology. 15: 1432-1439. PMID 167194 DOI: 10.1128/Jvi.15.6.1432-1439.1975 |
0.339 |
|
| 1975 |
Spector DH, Baltimore D. Polyadenylic acid on poliovirus RNA. II. Poly(A) on intracellular RNAs Journal of Virology. 15: 1418-1431. PMID 167193 DOI: 10.1128/Jvi.15.6.1418-1431.1975 |
0.323 |
|
| 1974 |
Spector DH, Baltimore D. Requirement of 3' terminal poly(adenylic acid) for the infectivity of poliovirus RNA Proceedings of the National Academy of Sciences of the United States of America. 71: 2983-2987. PMID 4370340 DOI: 10.1073/Pnas.71.8.2983 |
0.393 |
|
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