| Year |
Citation |
Score |
| 2024 |
Esfahani SN, Zheng Y, Arabpour A, Irizarry AMR, Kobayashi N, Xue X, Shao Y, Zhao C, Agranonik NL, Sparrow M, Hunt TJ, Faith J, Lara MJ, Wu QY, Silber S, ... ... Clark AT, et al. Derivation of human primordial germ cell-like cells in an embryonic-like culture. Nature Communications. 15: 167. PMID 38167821 DOI: 10.1038/s41467-023-43871-2 |
0.499 |
|
| 2023 |
Verdikt R, Armstrong AA, Cheng J, Hwang YS, Clark AT, Yang X, Allard P. Metabolic memory of Δ9-tetrahydrocannabinol exposure in pluripotent stem cells and primordial germ cells-like cells. Elife. 12. PMID 38150302 DOI: 10.7554/eLife.88795 |
0.379 |
|
| 2023 |
Lara MJD, Wamaitha SE, Arabpour A, Hennebold JD, Clark AT, Sosa E. Generation of a rhesus macaque induced pluripotent stem cell line (riPSC05) under feeder-free conditions. Stem Cell Research. 73: 103241. PMID 37976652 DOI: 10.1016/j.scr.2023.103241 |
0.434 |
|
| 2023 |
Sosa E, Mumu SK, Alvarado CC, Wu QY, Roberson I, Espinoza A, Hsu FM, Saito K, Hunt TJ, Faith JE, Lowe MG, DiRusso JA, Clark AT. Reconstituted ovaries self-assemble without an ovarian surface epithelium. Stem Cell Reports. PMID 37890483 DOI: 10.1016/j.stemcr.2023.10.001 |
0.352 |
|
| 2023 |
Landecker HL, Clark AT. Human embryo models made from pluripotent stem cells are not synthetic; they aren't embryos, either. Cell Stem Cell. 30: 1290-1293. PMID 37802034 DOI: 10.1016/j.stem.2023.09.006 |
0.359 |
|
| 2023 |
Wamaitha SE, Nie X, Pandolfi EC, Wang X, Yang Y, Stukenborg JB, Cairns BR, Guo J, Clark AT. Single-cell analysis of the developing human ovary defines distinct insights into ovarian somatic and germline progenitors. Developmental Cell. PMID 37582368 DOI: 10.1016/j.devcel.2023.07.014 |
0.419 |
|
| 2023 |
Hsu FM, Wu QY, Fabyanic EB, Wei A, Wu H, Clark AT. TET1 facilitates specification of early human lineages including germ cells. Iscience. 26: 107191. PMID 37456839 DOI: 10.1016/j.isci.2023.107191 |
0.482 |
|
| 2023 |
DiRusso JA, Clark AT. Transposable elements in early human embryo development and embryo models. Current Opinion in Genetics & Development. 81: 102086. PMID 37441874 DOI: 10.1016/j.gde.2023.102086 |
0.358 |
|
| 2022 |
Pandolfi EC, Hsu FM, Duhon M, Zheng Y, Goldsmith S, Fu J, Silber SJ, Clark AT. In vitro germ cell induction from fertile and infertile monozygotic twin research participants. Cell Reports. Medicine. 3: 100782. PMID 36260988 DOI: 10.1016/j.xcrm.2022.100782 |
0.464 |
|
| 2022 |
Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, ... ... Clark AT, et al. TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids. Stem Cell Reports. PMID 36179695 DOI: 10.1016/j.stemcr.2022.08.013 |
0.448 |
|
| 2022 |
Lowe MG, Yen MR, Hsu FM, Hosohama L, Hu Z, Chitiashvili T, Hunt TJ, Gorgy I, Bernard M, Wamaitha SE, Chen PY, Clark AT. EED is required for mouse primordial germ cell differentiation in the embryonic gonad. Developmental Cell. PMID 35679863 DOI: 10.1016/j.devcel.2022.05.012 |
0.427 |
|
| 2022 |
Chitiashvili T, Hsu FM, Dror I, Plath K, Clark A. FGFR3 is expressed by human primordial germ cells and is repressed after meiotic initiation to form primordial oocytes. Stem Cell Reports. PMID 35594860 DOI: 10.1016/j.stemcr.2022.04.015 |
0.49 |
|
| 2022 |
Xiang X, Tao Y, DiRusso J, Hsu FM, Zhang J, Xue Z, Pontis J, Trono D, Liu W, Clark AT. Human reproduction is regulated by retrotransposons derived from ancient Hominidae-specific viral infections. Nature Communications. 13: 463. PMID 35075135 DOI: 10.1038/s41467-022-28105-1 |
0.449 |
|
| 2021 |
Desai VP, Chouaref J, Wu H, Pastor WA, Kan RL, Oey HM, Li Z, Ho J, Vonk KKD, San Leon Granado D, Christopher MA, Clark AT, Jacobsen SE, Daxinger L. The role of MORC3 in silencing transposable elements in mouse embryonic stem cells. Epigenetics & Chromatin. 14: 49. PMID 34706774 DOI: 10.1186/s13072-021-00420-9 |
0.426 |
|
| 2021 |
Pandolfi EC, Hunt TJ, Goldsmith S, Hurlbut K, Silber SJ, Clark AT. Generation of three human induced pluripotent stem cell sublines (UCLAi004-A, UCLAi004-B, and UCLAi004-C) for reproductive science research. Stem Cell Research. 54: 102446. PMID 34216981 DOI: 10.1016/j.scr.2021.102446 |
0.439 |
|
| 2021 |
Pandolfi EC, Hunt TJ, Goldsmith S, Hurlbut K, Silber SJ, Clark AT. Generation of three human induced pluripotent stem cell sublines (UCLAi004-A, UCLAi004-B, and UCLAi004-C) for reproductive science research. Stem Cell Research. 54: 102446. PMID 34216981 DOI: 10.1016/j.scr.2021.102446 |
0.439 |
|
| 2021 |
Pandolfi EC, Hunt TJ, Goldsmith S, Hurlbut K, Silber SJ, Clark AT. Generation of three human induced pluripotent stem cell sublines (UCLAi005-A, UCLAi005-B and UCLAi005-C) for reproductive science research. Stem Cell Research. 54: 102409. PMID 34130154 DOI: 10.1016/j.scr.2021.102409 |
0.468 |
|
| 2021 |
Lovell-Badge R, Anthony E, Barker RA, Bubela T, Brivanlou AH, Carpenter M, Charo RA, Clark A, Clayton E, Cong Y, Daley GQ, Fu J, Fujita M, Greenfield A, Goldman SA, et al. ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem Cell Reports. PMID 34048692 DOI: 10.1016/j.stemcr.2021.05.012 |
0.384 |
|
| 2021 |
Clark AT, Brivanlou A, Fu J, Kato K, Mathews D, Niakan KK, Rivron N, Saitou M, Surani A, Tang F, Rossant J. Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines. Stem Cell Reports. PMID 34048690 DOI: 10.1016/j.stemcr.2021.05.008 |
0.405 |
|
| 2021 |
Liu X, Tan JP, Schröder J, Aberkane A, Ouyang JF, Mohenska M, Lim SM, Sun YBY, Chen J, Sun G, Zhou Y, Poppe D, Lister R, Clark AT, Rackham OJL, et al. Modelling human blastocysts by reprogramming fibroblasts into iBlastoids. Nature. PMID 33731926 DOI: 10.1038/s41586-021-03372-y |
0.482 |
|
| 2021 |
Hancock GV, Wamaitha SE, Peretz L, Clark AT. Mammalian primordial germ cell specification. Development (Cambridge, England). 148. PMID 33722957 DOI: 10.1242/dev.189217 |
0.412 |
|
| 2021 |
Pandolfi EC, Sosa E, Hunt TJ, Goldsmith S, Hurlbut K, Silber SJ, Clark AT. Generation of six human induced pluripotent stem cell sublines (MZT01E, MZT01F, MZT01N and MZT02D, MZT02G and MZT02H) for reproductive science research. Stem Cell Research. 51: 102204. PMID 33548810 DOI: 10.1016/j.scr.2021.102204 |
0.445 |
|
| 2021 |
Guo J, Sosa E, Chitiashvili T, Nie X, Rojas EJ, Oliver E, Plath K, Hotaling JM, Stukenborg JB, Clark AT, Cairns BR. Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment. Cell Stem Cell. PMID 33453151 DOI: 10.1016/j.stem.2020.12.004 |
0.477 |
|
| 2020 |
Liu X, Ouyang JF, Rossello FJ, Tan JP, Davidson KC, Valdes DS, Schröder J, Sun YBY, Chen J, Knaupp AS, Sun G, Chy HS, Huang Z, Pflueger J, Firas J, ... ... Clark AT, et al. Reprogramming roadmap reveals route to human induced trophoblast stem cells. Nature. PMID 32939092 DOI: 10.1038/S41586-020-2734-6 |
0.631 |
|
| 2020 |
Gell JJ, Liu W, Sosa E, Chialastri A, Hancock G, Tao Y, Wamaitha SE, Bower G, Dey SS, Clark AT. An Extended Culture System that Supports Human Primordial Germ Cell-like Cell Survival and Initiation of DNA Methylation Erasure. Stem Cell Reports. PMID 32059791 DOI: 10.1016/J.Stemcr.2020.01.009 |
0.584 |
|
| 2019 |
Chen D, Sun N, Hou L, Kim R, Faith J, Aslanyan M, Tao Y, Zheng Y, Fu J, Liu W, Kellis M, Clark A. Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors. Cell Reports. 29: 4568-4582.e5. PMID 31875561 DOI: 10.1016/J.Celrep.2019.11.083 |
0.631 |
|
| 2019 |
Vijayaraj P, Minasyan A, Durra A, Karumbayaram S, Mehrabi M, Aros CJ, Ahadome SD, Shia DW, Chung K, Sandlin JM, Darmawan KF, Bhatt KV, Manze CC, Paul MK, Wilkinson DC, ... ... Clark AT, et al. Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule. Cell Reports. 29: 3488-3505.e9. PMID 31825831 DOI: 10.1016/J.Celrep.2019.11.019 |
0.376 |
|
| 2019 |
Clark AT. Standing on the shoulders of giants: The changing landscape of pluripotent stem cells in research. Anatomical Record (Hoboken, N.J. : 2007). PMID 31751000 DOI: 10.1002/Ar.24304 |
0.585 |
|
| 2019 |
Pandolfi EC, Rojas EJ, Sosa E, Gell JJ, Hunt TJ, Goldsmith S, Fan Y, Silber SJ, Clark AT. Generation of three human induced pluripotent stem cell sublines (MZT04D, MZT04J, MZT04C) for reproductive science research. Stem Cell Research. 40: 101576. PMID 31622877 DOI: 10.1016/J.Scr.2019.101576 |
0.545 |
|
| 2018 |
Chen D, Liu W, Zimmerman J, Pastor WA, Kim R, Hosohama L, Ho J, Aslanyan M, Gell JJ, Jacobsen SE, Clark AT. The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation. Cell Reports. 25: 3591-3602.e5. PMID 30590035 DOI: 10.1016/J.Celrep.2018.12.011 |
0.588 |
|
| 2018 |
Sosa E, Chen D, Rojas EJ, Hennebold JD, Peters KA, Wu Z, Lam TN, Mitchell JM, Sukhwani M, Tailor RC, Meistrich ML, Orwig KE, Shetty G, Clark AT. Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. Nature Communications. 9: 5339. PMID 30559363 DOI: 10.1038/S41467-018-07740-7 |
0.539 |
|
| 2018 |
Gell JJ, Clark AT. Restoring Fertility with Human Induced Pluripotent Stem Cells: Are We There Yet? Cell Stem Cell. 23: 777-779. PMID 30526878 DOI: 10.1016/J.Stem.2018.11.003 |
0.404 |
|
| 2018 |
Pastor WA, Liu W, Chen D, Ho J, Kim R, Hunt TJ, Lukianchikov A, Liu X, Polo JM, Jacobsen SE, Clark AT. TFAP2C regulates transcription in human naive pluripotency by opening enhancers. Nature Cell Biology. 20: 553-564. PMID 29695788 DOI: 10.1038/S41556-018-0089-0 |
0.5 |
|
| 2018 |
Chen D, Clark AT. Mitochondrial DNA selection in human germ cells. Nature Cell Biology. 20: 118-120. PMID 29371703 DOI: 10.1038/S41556-017-0029-4 |
0.35 |
|
| 2018 |
Gupta S, Sivalingam D, Hain S, Makkar C, Sosa E, Clark A, Butler SJ. Deriving Dorsal Spinal Sensory Interneurons from Human Pluripotent Stem Cells. Stem Cell Reports. PMID 29337120 DOI: 10.1016/J.Stemcr.2017.12.012 |
0.468 |
|
| 2018 |
Gell JJ, Zhao J, Chen D, Hunt TJ, Clark AT. PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. Stem Cell Research. 27: 46-56. PMID 29324254 DOI: 10.1016/J.Scr.2017.12.016 |
0.557 |
|
| 2017 |
Tao Y, Yen MR, Chitiashvili T, Nakano H, Kim R, Hosohama L, Tan YC, Nakano A, Chen PY, Clark AT. TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency. Stem Cell Reports. PMID 29290627 DOI: 10.1016/J.Stemcr.2017.11.020 |
0.475 |
|
| 2017 |
Chen D, Liu W, Lukianchikov A, Hancock G, Zimmerman J, Lowe M, Kim R, Galic Z, Irie N, Surani MA, Jacobsen SE, Clark AT. Germline competency of human embryonic stem cells depends on EOMESODERMIN. Biology of Reproduction. PMID 29091993 DOI: 10.1093/Biolre/Iox138 |
0.609 |
|
| 2017 |
Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M. Correction: In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse. Elife. 6. PMID 28858608 DOI: 10.7554/Elife.30948 |
0.302 |
|
| 2017 |
Sosa E, Kim R, Rojas EJ, Hosohama L, Hennebold JD, Orwig KE, Clark AT. An integration-free, virus-free rhesus macaque induced pluripotent stem cell line (riPSC90) from embryonic fibroblasts. Stem Cell Research. 21: 5-8. PMID 28677539 DOI: 10.1016/J.Scr.2017.03.011 |
0.519 |
|
| 2017 |
Clark AT, Gkountela S, Chen D, Liu W, Sosa E, Sukhwani M, Hennebold JD, Orwig KE. Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. Stem Cell Reports. PMID 28579394 DOI: 10.1016/J.Stemcr.2017.05.002 |
0.503 |
|
| 2017 |
Chen D, Gell JJ, Tao Y, Sosa E, Clark AT. Modeling human infertility with pluripotent stem cells. Stem Cell Research. PMID 28431857 DOI: 10.1016/J.Scr.2017.04.005 |
0.632 |
|
| 2017 |
Nagaraj R, Sharpley MS, Chi F, Braas D, Zhou Y, Kim R, Clark AT, Banerjee U. Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation. Cell. 168: 210-223.e11. PMID 28086092 DOI: 10.1016/J.Cell.2016.12.026 |
0.344 |
|
| 2016 |
O'Brien CM, Chy HS, Zhou Q, Blumenfeld S, Lambshead JW, Liu X, Kie J, Capaldo BD, Chung TL, Adams TE, Phan T, Bentley JD, Mckinstry WJ, Oliva K, Mcmurrick PJ, ... ... Clark AT, et al. New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells. Stem Cells (Dayton, Ohio). PMID 28009074 DOI: 10.1002/Stem.2558 |
0.578 |
|
| 2016 |
Sahakyan A, Kim R, Chronis C, Sabri S, Bonora G, Theunissen TW, Kuoy E, Langerman J, Clark AT, Jaenisch R, Plath K. Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation. Cell Stem Cell. PMID 27989770 DOI: 10.1016/J.Stem.2016.10.006 |
0.459 |
|
| 2016 |
Patel S, Bonora G, Sahakyan A, Kim R, Chronis C, Langerman J, Fitz-Gibbon S, Rubbi L, Skelton RJ, Ardehali R, Pellegrini M, Lowry WE, Clark AT, Plath K. Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. Cell Reports. PMID 27989715 DOI: 10.1016/J.Celrep.2016.11.054 |
0.453 |
|
| 2016 |
Masaeli M, Gupta D, O'Byrne S, Tse HT, Gossett DR, Tseng P, Utada AS, Jung HJ, Young S, Clark AT, Di Carlo D. Multiparameter mechanical and morphometric screening of cells. Scientific Reports. 6: 37863. PMID 27910869 DOI: 10.1038/Srep37863 |
0.388 |
|
| 2016 |
Sosa E, Kim R, Rojas EJ, Hosohama L, Hennebold JD, Orwig KE, Clark AT. An integration-free, virus-free rhesus macaque induced pluripotent stem cell line (riPSC89) from embryonic fibroblasts. Stem Cell Research. 17: 444-447. PMID 27879222 DOI: 10.1016/J.Scr.2016.09.015 |
0.521 |
|
| 2016 |
Hargan-Calvopina J, Taylor S, Cook H, Hu Z, Lee SA, Yen MR, Chiang YS, Chen PY, Clark AT. Stage-Specific Demethylation in Primordial Germ Cells Safeguards against Precocious Differentiation. Developmental Cell. PMID 27618282 DOI: 10.1016/J.Devcel.2016.07.019 |
0.414 |
|
| 2016 |
Pastor WA, Chen D, Liu W, Kim R, Sahakyan A, Lukianchikov A, Plath K, Jacobsen SE, Clark AT. Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. Cell Stem Cell. 18: 323-329. PMID 26853856 DOI: 10.1016/J.Stem.2016.01.019 |
0.539 |
|
| 2015 |
Clark AT, Zwaka TP. Editorial overview: Cell reprogramming, regeneration and repair: Reprogramming: the eternal circle. Current Opinion in Genetics & Development. PMID 26476785 DOI: 10.1016/J.Gde.2015.09.006 |
0.486 |
|
| 2015 |
Clark AT. DNA methylation remodeling in vitro and in vivo. Current Opinion in Genetics & Development. 34: 82-87. PMID 26451496 DOI: 10.1016/J.Gde.2015.09.002 |
0.481 |
|
| 2015 |
Oliveros-Etter M, Li Z, Nee K, Hosohama L, Hargan-Calvopina J, Lee SA, Joti P, Yu J, Clark AT. PGC Reversion to Pluripotency Involves Erasure of DNA Methylation from Imprinting Control Centers followed by Locus-Specific Re-methylation. Stem Cell Reports. PMID 26278040 DOI: 10.1016/J.Stemcr.2015.07.006 |
0.662 |
|
| 2015 |
Gkountela S, Zhang KX, Shafiq TA, Liao WW, Hargan-Calvopiña J, Chen PY, Clark AT. DNA Demethylation Dynamics in the Human Prenatal Germline. Cell. 161: 1425-36. PMID 26004067 DOI: 10.1016/J.Cell.2015.05.012 |
0.51 |
|
| 2015 |
Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M. In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse. Elife. 4: e06205. PMID 25848745 DOI: 10.7554/Elife.06205 |
0.309 |
|
| 2015 |
Chen D, Clark AT. Human germline differentiation charts a new course. The Embo Journal. 34: 975-7. PMID 25787856 DOI: 10.15252/Embj.201591447 |
0.551 |
|
| 2015 |
Calvopina JH, Cook H, Vincent JJ, Nee K, Clark AT. The Aorta-Gonad-Mesonephros Organ Culture Recapitulates 5hmC Reorganization and Replication-Dependent and Independent Loss of DNA Methylation in the Germline. Stem Cells and Development. 24: 1536-45. PMID 25749005 DOI: 10.1089/Scd.2014.0410 |
0.651 |
|
| 2015 |
Li Z, Yu J, Hosohama L, Nee K, Gkountela S, Chaudhari S, Cass AA, Xiao X, Clark AT. The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice. The Embo Journal. 34: 748-58. PMID 25519955 DOI: 10.15252/Embj.201489319 |
0.635 |
|
| 2014 |
Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE. MORC1 represses transposable elements in the mouse male germline. Nature Communications. 5: 5795. PMID 25503965 DOI: 10.1038/Ncomms6795 |
0.394 |
|
| 2014 |
Gkountela S, Clark AT. A big surprise in the little zygote: the curious business of losing methylated cytosines. Cell Stem Cell. 15: 393-4. PMID 25280211 DOI: 10.1016/J.Stem.2014.09.005 |
0.509 |
|
| 2014 |
Ben-David U, Arad G, Weissbein U, Mandefro B, Maimon A, Golan-Lev T, Narwani K, Clark AT, Andrews PW, Benvenisty N, Carlos Biancotti J. Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells. Nature Communications. 5: 4825. PMID 25198699 DOI: 10.1038/Ncomms5825 |
0.576 |
|
| 2014 |
Durruthy-Durruthy J, Briggs SF, Awe J, Ramathal CY, Karumbayaram S, Lee PC, Heidmann JD, Clark A, Karakikes I, Loh KM, Wu JC, Hoffman AR, Byrne J, Reijo Pera RA, Sebastiano V. Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions. Plos One. 9: e94231. PMID 24718618 DOI: 10.1371/Journal.Pone.0094231 |
0.694 |
|
| 2014 |
Gkountela S, Li Z, Chin CJ, Lee SA, Clark AT. PRMT5 is required for human embryonic stem cell proliferation but not pluripotency. Stem Cell Reviews. 10: 230-9. PMID 24477620 DOI: 10.1007/S12015-013-9490-Z |
0.714 |
|
| 2014 |
Valli H, Phillips BT, Shetty G, Byrne JA, Clark AT, Meistrich ML, Orwig KE. Germline stem cells: toward the regeneration of spermatogenesis. Fertility and Sterility. 101: 3-13. PMID 24314923 DOI: 10.1016/J.Fertnstert.2013.10.052 |
0.442 |
|
| 2014 |
Kim R, Clark AT. Hatching human blastocyst Molecular Reproduction and Development. 81: 203-203. DOI: 10.1002/Mrd.22313 |
0.387 |
|
| 2013 |
Gkountela S, Clark AT. RNA-Seq Library Generation from Rare Human Cells Isolated by FACS. Bio-Protocol. 3. PMID 27441203 |
0.32 |
|
| 2013 |
Feng Y, Maity R, Whitelegge JP, Hadjikyriacou A, Li Z, Zurita-Lopez C, Al-Hadid Q, Clark AT, Bedford MT, Masson JY, Clarke SG. Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions. The Journal of Biological Chemistry. 288: 37010-25. PMID 24247247 DOI: 10.1074/Jbc.M113.525345 |
0.51 |
|
| 2013 |
Clark A. Human somatic cell nuclear transfer: A scientist's perspective Molecular Reproduction and Development. 80: 2-4. PMID 24078473 DOI: 10.1002/Mrd.22260 |
0.428 |
|
| 2013 |
Awe JP, Lee PC, Ramathal C, Vega-Crespo A, Durruthy-Durruthy J, Cooper A, Karumbayaram S, Lowry WE, Clark AT, Zack JA, Sebastiano V, Kohn DB, Pyle AD, Martin MG, Lipshutz GS, et al. Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. Stem Cell Research & Therapy. 4: 87. PMID 23890092 DOI: 10.1186/Scrt246 |
0.554 |
|
| 2013 |
Vincent JJ, Huang Y, Chen PY, Feng S, Calvopiña JH, Nee K, Lee SA, Le T, Yoon AJ, Faull K, Fan G, Rao A, Jacobsen SE, Pellegrini M, Clark AT. Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells. Cell Stem Cell. 12: 470-8. PMID 23415914 DOI: 10.1016/J.Stem.2013.01.016 |
0.676 |
|
| 2013 |
Gkountela S, Li Z, Vincent JJ, Zhang KX, Chen A, Pellegrini M, Clark AT. The ontogeny of cKIT+ human primordial germ cells proves to be a resource for human germ line reprogramming, imprint erasure and in vitro differentiation. Nature Cell Biology. 15: 113-22. PMID 23242216 DOI: 10.1038/Ncb2638 |
0.786 |
|
| 2012 |
Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE. From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Translational Medicine. 1: 36-43. PMID 23197638 DOI: 10.5966/Sctm.2011-0001 |
0.486 |
|
| 2012 |
Clark AT. Pluripotency takes off without Blimp1. Cell Stem Cell. 11: 1-2. PMID 22770234 DOI: 10.1016/J.Stem.2012.06.001 |
0.561 |
|
| 2012 |
Deshpande AM, Khalid O, Kim JJ, Kim Y, Lindgren A, Clark AT, Wong DT. Cdk2ap2 is a novel regulator for self-renewal of murine embryonic stem cells. Stem Cells and Development. 21: 3010-8. PMID 22548356 DOI: 10.1089/Scd.2012.0007 |
0.578 |
|
| 2012 |
Gossett DR, Tse HT, Lee SA, Ying Y, Lindgren AG, Yang OO, Rao J, Clark AT, Di Carlo D. Hydrodynamic stretching of single cells for large population mechanical phenotyping. Proceedings of the National Academy of Sciences of the United States of America. 109: 7630-5. PMID 22547795 DOI: 10.1073/Pnas.1200107109 |
0.462 |
|
| 2012 |
Diaz Perez SV, Kim R, Li Z, Marquez VE, Patel S, Plath K, Clark AT. Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin. Human Molecular Genetics. 21: 751-64. PMID 22058289 DOI: 10.1093/Hmg/Ddr506 |
0.605 |
|
| 2012 |
Masaeli M, Tse HTK, Gossett DR, Clark AT, Di Carlo D. Deformability cytometry of embryonic stem cells reveals consistent mechanical properties across cell lines Proceedings of the 16th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2012. 974-976. |
0.48 |
|
| 2011 |
Vincent JJ, Li Z, Lee SA, Liu X, Etter MO, Diaz-Perez SV, Taylor SK, Gkountela S, Lindgren AG, Clark AT. Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells. Plos One. 6: e28960. PMID 22194959 DOI: 10.1371/Journal.Pone.0028960 |
0.771 |
|
| 2011 |
Azghadi S, Clark AT. Epigenetically reprogramming of human embryonic stem cells by 3-deazaneplanocin a and sodium butyrate. International Journal of Preventive Medicine. 2: 73-8. PMID 21603011 |
0.46 |
|
| 2011 |
Mandal S, Lindgren AG, Srivastava AS, Clark AT, Banerjee U. Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells. Stem Cells (Dayton, Ohio). 29: 486-95. PMID 21425411 DOI: 10.1002/Stem.590 |
0.494 |
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| 2011 |
Lindgren AG, Natsuhara K, Tian E, Vincent JJ, Li X, Jiao J, Wu H, Banerjee U, Clark AT. Loss of Pten causes tumor initiation following differentiation of murine pluripotent stem cells due to failed repression of Nanog. Plos One. 6: e16478. PMID 21304588 DOI: 10.1371/Journal.Pone.0016478 |
0.721 |
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| 2011 |
Clark A. The Next Frontier for Pluripotent Stem Cell Research in Reproductive Biology. Biology of Reproduction. 85: 157-157. DOI: 10.1093/Biolreprod/85.S1.157 |
0.516 |
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| 2011 |
Kamei Ki, Ohashi M, Graham NA, Chen Y, Clark AT, Witte ON, Graeber TG, Pyle AD, Tseng HR. Quantitative cytological feature analysis by microfluidic image cytometry reveals phenotypic differences among human pluripotent stem cell lines 15th International Conference On Miniaturized Systems For Chemistry and Life Sciences 2011, Microtas 2011. 1: 148-150. |
0.388 |
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| 2010 |
Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, Plath K, Lowry WE, Benvenisty N. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell. 7: 521-31. PMID 20887957 DOI: 10.1016/J.Stem.2010.07.017 |
0.568 |
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| 2010 |
Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K. Female human iPSCs retain an inactive X chromosome. Cell Stem Cell. 7: 329-42. PMID 20727844 DOI: 10.1016/J.Stem.2010.06.024 |
0.49 |
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| 2010 |
Ambartsumyan G, Gill RK, Perez SD, Conway D, Vincent J, Dalal Y, Clark AT. Centromere protein A dynamics in human pluripotent stem cell self-renewal, differentiation and DNA damage. Human Molecular Genetics. 19: 3970-82. PMID 20650959 DOI: 10.1093/Hmg/Ddq312 |
0.798 |
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| 2010 |
Biancotti JC, Narwani K, Buehler N, Mandefro B, Golan-Lev T, Yanuka O, Clark A, Hill D, Benvenisty N, Lavon N. Human embryonic stem cells as models for aneuploid chromosomal syndromes. Stem Cells (Dayton, Ohio). 28: 1530-40. PMID 20641042 DOI: 10.1002/Stem.483 |
0.431 |
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| 2010 |
Kamei K, Ohashi M, Gschweng E, Ho Q, Suh J, Tang J, For Yu ZT, Clark AT, Pyle AD, Teitell MA, Lee KB, Witte ON, Tseng HR. Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions. Lab On a Chip. 10: 1113-9. PMID 20390128 DOI: 10.1039/B922884E |
0.453 |
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| 2010 |
Clark AT. Egg-citing advances in generating primordial germ cells in the laboratory. Biology of Reproduction. 82: 233-4. PMID 20018911 DOI: 10.1095/Biolreprod.109.082388 |
0.566 |
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| 2010 |
Ambartsumyan G, Conway D, Vincent J, Clark A. Lack of checkpoint control in human pluripotent stem cells: a cause for genomic instability? Fertility and Sterility. 94: S240. DOI: 10.1016/J.Fertnstert.2010.07.931 |
0.803 |
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| 2010 |
Ambartsumyan G, Diaz Perez S, Clark A. Centromere protein A (CENP-A) dynamics in human pluripotent stem cell self renewal, differentiation and dna repair Fertility and Sterility. 94: S8. DOI: 10.1016/J.Fertnstert.2010.07.030 |
0.769 |
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| 2009 |
Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, ... ... Clark AT, et al. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 5: 111-23. PMID 19570518 DOI: 10.1016/J.Stem.2009.06.008 |
0.777 |
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| 2009 |
Kim Y, Deshpande A, Dai Y, Kim JJ, Lindgren A, Conway A, Clark AT, Wong DT. Cyclin-dependent kinase 2-associating protein 1 commits murine embryonic stem cell differentiation through retinoblastoma protein regulation. The Journal of Biological Chemistry. 284: 23405-14. PMID 19564334 DOI: 10.1074/Jbc.M109.026088 |
0.521 |
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| 2009 |
Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells (Dayton, Ohio). 27: 806-11. PMID 19350680 DOI: 10.1002/Stem.31 |
0.41 |
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| 2009 |
Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ, Magnusson M, Richter L, Teitell MA, Mikkola HK, Lowry WE, Plath K, Clark AT. Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells (Dayton, Ohio). 27: 783-95. PMID 19350678 DOI: 10.1002/Stem.13 |
0.642 |
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| 2009 |
Xie W, Song C, Young NL, Sperling AS, Xu F, Sridharan R, Conway AE, Garcia BA, Plath K, Clark AT, Grunstein M. Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Molecular Cell. 33: 417-27. PMID 19250903 DOI: 10.1016/J.Molcel.2009.02.004 |
0.471 |
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| 2009 |
Conway AE, Lindgren A, Galic Z, Pyle AD, Wu H, Zack JA, Pelligrini M, Teitell MA, Clark AT. A self-renewal program controls the expansion of genetically unstable cancer stem cells in pluripotent stem cell-derived tumors. Stem Cells (Dayton, Ohio). 27: 18-28. PMID 19224508 DOI: 10.1634/Stemcells.2008-0529 |
0.493 |
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| 2008 |
Ambartsumyan G, Clark AT. Aneuploidy and early human embryo development. Human Molecular Genetics. 17: R10-5. PMID 18632690 DOI: 10.1093/Hmg/Ddn170 |
0.762 |
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| 2008 |
Wu H, Kim KJ, Mehta K, Paxia S, Sundstrom A, Anantharaman T, Kuraishy AI, Doan T, Ghosh J, Pyle AD, Clark A, Lowry W, Fan G, Baxter T, Mishra B, et al. Copy number variant analysis of human embryonic stem cells. Stem Cells (Dayton, Ohio). 26: 1484-9. PMID 18369100 DOI: 10.1634/Stemcells.2007-0993 |
0.484 |
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| 2008 |
Lowry WE, Richter L, Yachechko R, Pyle AD, Tchieu J, Sridharan R, Clark AT, Plath K. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 105: 2883-8. PMID 18287077 DOI: 10.1073/Pnas.0711983105 |
0.639 |
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| 2007 |
Clark AT. The stem cell identity of testicular cancer. Stem Cell Reviews. 3: 49-59. PMID 17873381 DOI: 10.1007/S12015-007-0002-X |
0.571 |
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| 2007 |
Bostick M, Kim JK, Estève PO, Clark A, Pradhan S, Jacobsen SE. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science (New York, N.Y.). 317: 1760-4. PMID 17673620 DOI: 10.1126/Science.1147939 |
0.329 |
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| 2007 |
Clark AT. Establishment and differentiation of human embryonic stem cell derived germ cells. Society of Reproduction and Fertility Supplement. 63: 77-86. PMID 17566263 |
0.543 |
|
| 2007 |
Fox MS, Clark AT, El Majdoubi M, Vigne JL, Urano J, Hostetler CE, Griswold MD, Weiner RI, Reijo Pera RA. Intermolecular interactions of homologs of germ plasm components in mammalian germ cells. Developmental Biology. 301: 417-31. PMID 16996493 DOI: 10.1016/J.Ydbio.2006.08.047 |
0.757 |
|
| 2006 |
Clark AT, Reijo Pera RA. Modeling human germ cell development with embryonic stem cells. Regenerative Medicine. 1: 85-93. PMID 17465822 DOI: 10.2217/17460751.1.1.85 |
0.778 |
|
| 2006 |
Kee K, Gonsalves JM, Clark AT, Pera RA. Bone morphogenetic proteins induce germ cell differentiation from human embryonic stem cells. Stem Cells and Development. 15: 831-7. PMID 17253946 DOI: 10.1089/Scd.2006.15.831 |
0.763 |
|
| 2006 |
Fox MS, Pera RAR, Clark AT. The DAZ gene family and human germ cell development from embryonic stem cells The Sperm Cell: Production, Maturation, Fertilization, Regeneration. 323-350. DOI: 10.1017/CBO9780511545115.013 |
0.488 |
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| 2006 |
Shefi S, Fox MS, Clark AT, Reijo Pera RA, Turek PJ. 1421: Isolation, Enrichment and Characterization of Human Type a Spermatogonia Journal of Urology. 175: 458-459. DOI: 10.1016/S0022-5347(18)33625-5 |
0.315 |
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| 2005 |
Ezeh UI, Turek PJ, Reijo RA, Clark AT. Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma. Cancer. 104: 2255-65. PMID 16228988 DOI: 10.1002/Cncr.21432 |
0.514 |
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| 2005 |
Turek PJ, Ezeh UO, Reijo Pera RA, Clark AT. 434: The Cell of Origin of Testicular Seminoma: A Genetic Analysis Journal of Urology. 173: 118-119. DOI: 10.1016/S0022-5347(18)34687-1 |
0.357 |
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| 2005 |
Ezeh U, Turek P, Pera RR, Clark A. Human Embryonic Stem Cell Genes are Expressed in both Human Germ and Non-Germ Cell Cancers Fertility and Sterility. 84: S62. DOI: 10.1016/J.Fertnstert.2005.07.149 |
0.579 |
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| 2004 |
Clark AT, Rodriguez RT, Bodnar MS, Abeyta MJ, Cedars MI, Turek PJ, Firpo MT, Reijo Pera RA. Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma. Stem Cells (Dayton, Ohio). 22: 169-79. PMID 14990856 DOI: 10.1634/Stemcells.22-2-169 |
0.755 |
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| 2004 |
Clark AT, Bodnar MS, Fox M, Rodriquez RT, Abeyta MJ, Firpo MT, Pera RA. Spontaneous differentiation of germ cells from human embryonic stem cells in vitro. Human Molecular Genetics. 13: 727-39. PMID 14962983 DOI: 10.1093/Hmg/Ddh088 |
0.622 |
|
| 2004 |
Abeyta MJ, Clark AT, Rodriguez RT, Bodnar MS, Pera RA, Firpo MT. Unique gene expression signatures of independently-derived human embryonic stem cell lines. Human Molecular Genetics. 13: 601-8. PMID 14749348 DOI: 10.1093/Hmg/Ddh068 |
0.508 |
|
| 2004 |
Clark AT, Firozi K, Justice MJ. Mutations in a novel locus on mouse chromosome 11 resulting in male infertility associated with defects in microtubule assembly and sperm tail function. Biology of Reproduction. 70: 1317-24. PMID 14711786 DOI: 10.1095/Biolreprod.103.020628 |
0.302 |
|
| 2003 |
Kile BT, Hentges KE, Clark AT, Nakamura H, Salinger AP, Liu B, Box N, Stockton DW, Johnson RL, Behringer RR, Bradley A, Justice MJ. Functional genetic analysis of mouse chromosome 11. Nature. 425: 81-6. PMID 12955145 DOI: 10.1038/Nature01865 |
0.323 |
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| 2001 |
Martinez G, Loveland KL, Clark AT, Dziadek M, Bertram JF. Expression of bone morphogenetic protein receptors in the developing mouse metanephros Experimental Nephrology. 9: 372-379. PMID 11701996 DOI: 10.1159/000052635 |
0.506 |
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| 2001 |
Clark AT, Young RJ, Bertram JF. In vitro studies on the roles of transforming growth factor-β1 in rat metanephric development Kidney International. 59: 1641-1653. PMID 11318934 DOI: 10.1046/J.1523-1755.2001.0590051641.X |
0.459 |
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| 2000 |
Joyce IM, Clark AT, Pendola FL, Eppig JJ. Comparison of recombinant growth differentiation factor-9 and oocyte regulation of KIT ligand messenger ribonucleic acid expression in mouse ovarian follicles Biology of Reproduction. 63: 1669-1675. PMID 11090434 DOI: 10.1095/Biolreprod63.6.1669 |
0.388 |
|
| 2000 |
Clark AT, Bertram JF. Advances in renal development Current Opinion in Nephrology and Hypertension. 9: 247-251. PMID 10847325 DOI: 10.1097/00041552-200005000-00007 |
0.544 |
|
| 1999 |
Clark AT, Bertram JF. Molecular regulation of nephron endowment. American Journal of Physiology. Renal Physiology. 276: F485-F497. PMID 29591425 DOI: 10.1152/ajprenal.1999.276.4.F485 |
0.496 |
|
| 1999 |
Elvin JA, Clark AT, Wang P, Wolfman NM, Matzuk MM. Paracrine actions of growth differentiation factor-9 in the mammalian ovary Molecular Endocrinology. 13: 1035-1048. PMID 10379900 DOI: 10.1210/Mend.13.6.0310 |
0.418 |
|
| 1999 |
Clark AT, Bertram JF. Molecular regulation of nephron endowment American Journal of Physiology - Renal Physiology. 276. PMID 10198407 |
0.496 |
|
| 1995 |
CLARK AT, FORD MD, NURCOMBE V, ALCORN D, KEY B, PUCHE AC, BERTRAM JF. Expression of transforming growth factor-? type II receptor mRNA in embryonic and adult rat kidney Nephrology. 1: 547-553. DOI: 10.1111/J.1440-1797.1995.Tb00054.X |
0.455 |
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