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Margaret A. Scull, Ph.D. - Publications

Affiliations: 
2009 Microbiology & Immunology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Microbiology Biology, Virology Biology
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kaler L, Engle EM, Iverson E, Boboltz A, Ignacio MA, Rife M, Scull MA, Duncan GA. Mucus physically restricts influenza A viral particle access to the epithelium. Biorxiv : the Preprint Server For Biology. PMID 37645821 DOI: 10.1101/2023.08.14.553271  0.376
2022 Iverson E, Griswold K, Song D, Gagliardi TB, Hamidzadeh K, Kesimer M, Sinha S, Perry M, Duncan GA, Scull MA. Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium. Mbio. e0105522. PMID 35699372 DOI: 10.1128/mbio.01055-22  0.541
2022 Gagliardi TB, Iverson E, DeGrace EJ, Rosenberg BR, Scull MA. Immunofluorescence-Mediated Detection of Respiratory Virus Infections in Human Airway Epithelial Cultures. Current Protocols. 2: e453. PMID 35671174 DOI: 10.1002/cpz1.453  0.455
2022 Kaler L, Iverson E, Bader S, Song D, Scull MA, Duncan GA. Influenza A virus diffusion through mucus gel networks. Communications Biology. 5: 249. PMID 35318436 DOI: 10.1038/s42003-022-03204-3  0.456
2022 Gagliardi TB, Goldstein ME, Song D, Gray KM, Jung JW, Ignacio MA, Stroka KM, Duncan GA, Scull MA. Rhinovirus C replication is associated with the endoplasmic reticulum and triggers cytopathic effects in an in vitro model of human airway epithelium. Plos Pathogens. 18: e1010159. PMID 34995322 DOI: 10.1371/journal.ppat.1010159  0.34
2021 Goldstein ME, Scull MA. Modeling Innate Antiviral Immunity in Physiological Context. Journal of Molecular Biology. 167374. PMID 34863779 DOI: 10.1016/j.jmb.2021.167374  0.403
2020 Iverson E, Kaler L, Agostino EL, Song D, Duncan GA, Scull MA. Leveraging 3D Model Systems to Understand Viral Interactions with the Respiratory Mucosa. Viruses. 12. PMID 33322395 DOI: 10.3390/v12121425  0.435
2017 Hoffmann HH, Schneider WM, Blomen VA, Scull MA, Hovnanian A, Brummelkamp TR, Rice CM. Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread. Cell Host & Microbe. 22: 460-470.e5. PMID 29024641 DOI: 10.1016/J.Chom.2017.09.002  0.537
2017 Takacs CN, Andreo U, Dao Thi VL, Wu X, Gleason CE, Itano MS, Spitz-Becker GS, Belote RL, Hedin BR, Scull MA, Rice CM, Simon SM. Differential Regulation of Lipoprotein and Hepatitis C Virus Secretion by Rab1b. Cell Reports. 21: 431-441. PMID 29020629 DOI: 10.1016/J.Celrep.2017.09.053  0.385
2017 Andreo U, de Jong YP, Scull MA, Xiao JW, Vercauteren K, Quirk C, Mommersteeg MC, Bergaya S, Menon A, Fisher EA, Rice CM. Analysis of Hepatitis C Virus Particle Heterogeneity in Immunodeficient Human Liver Chimeric fah-/- Mice. Cellular and Molecular Gastroenterology and Hepatology. 4: 405-417. PMID 28936471 DOI: 10.1016/J.Jcmgh.2017.07.002  0.377
2016 Takacs CN, Andreo U, Belote RL, Pulupa J, Scull MA, Gleason CE, Rice CM, Simon SM. GFP-tagged Apolipoprotein E: a useful marker for the study of hepatic lipoprotein egress. Traffic (Copenhagen, Denmark). PMID 28035714 DOI: 10.1111/Tra.12467  0.303
2015 Scull MA, Schneider WM, Flatley BR, Hayden R, Fung C, Jones CT, van de Belt M, Penin F, Rice CM. The N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production. Plos Pathogens. 11: e1005297. PMID 26588073 DOI: 10.1371/Journal.Ppat.1005297  0.359
2015 March S, Ramanan V, Trehan K, Ng S, Galstian A, Gural N, Scull MA, Shlomai A, Mota MM, Fleming HE, Khetani SR, Rice CM, Bhatia SN. Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens. Nature Protocols. 10: 2027-2053. PMID 26584444 DOI: 10.1038/Nprot.2015.128  0.423
2015 Scull MA, Shi C, de Jong YP, Gerold G, Ries M, von Schaewen M, Donovan BM, Labitt RN, Horwitz JA, Gaska JM, Hrebikova G, Xiao JW, Flatley B, Fung C, Chiriboga L, et al. Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice. Hepatology (Baltimore, Md.). 62: 57-67. PMID 25820364 DOI: 10.1002/Hep.27773  0.355
2015 Dittmann M, Hoffmann HH, Scull MA, Gilmore RH, Bell KL, Ciancanelli M, Wilson SJ, Crotta S, Yu Y, Flatley B, Xiao JW, Casanova JL, Wack A, Bieniasz PD, Rice CM. A serpin shapes the extracellular environment to prevent influenza A virus maturation. Cell. 160: 631-43. PMID 25679759 DOI: 10.1016/J.Cell.2015.01.040  0.559
2014 Ramanan V, Scull MA, Sheahan TP, Rice CM, Bhatia SN. New Methods in Tissue Engineering: Improved Models for Viral Infection. Annual Review of Virology. 1: 475-499. PMID 25893203 DOI: 10.1146/Annurev-Virology-031413-085437  0.436
2013 Vogt A, Scull MA, Friling T, Horwitz JA, Donovan BM, Dorner M, Gerold G, Labitt RN, Rice CM, Ploss A. Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines. Virology. 444: 1-11. PMID 23777661 DOI: 10.1016/J.Virol.2013.05.036  0.367
2012 Schaap-Nutt A, Liesman R, Bartlett EJ, Scull MA, Collins PL, Pickles RJ, Schmidt AC. Human parainfluenza virus serotypes differ in their kinetics of replication and cytokine secretion in human tracheobronchial airway epithelium. Virology. 433: 320-8. PMID 22959894 DOI: 10.1016/J.Virol.2012.08.027  0.682
2012 Scull MA, Ploss A. Exiting from uncharted territory: hepatitis C virus assembles in mouse cell lines. Hepatology (Baltimore, Md.). 55: 645-8. PMID 22287293 DOI: 10.1002/Hep.24716  0.385
2011 Ralston R, Jacobson I, Scull M. The conundrum of relapse in STAT-C therapy: does HCV play the Red Queen or Rip Van Winkle? Seminars in Liver Disease. 31: 410-9. PMID 22189980 DOI: 10.1055/S-0031-1297929  0.386
2011 Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways. Immunity. 34: 854-65. PMID 21703540 DOI: 10.1016/J.Immuni.2011.03.026  0.68
2011 Roberts KL, Shelton H, Scull M, Pickles R, Barclay WS. Lack of transmission of a human influenza virus with avian receptor specificity between ferrets is not due to decreased virus shedding but rather a lower infectivity in vivo. The Journal of General Virology. 92: 1822-31. PMID 21508186 DOI: 10.1099/Vir.0.031203-0  0.721
2010 Scull MA, Rice CM. A big role for small RNAs in influenza virus replication. Proceedings of the National Academy of Sciences of the United States of America. 107: 11153-4. PMID 20547839 DOI: 10.1073/Pnas.1006673107  0.535
2010 Schaap-Nutt A, Scull MA, Schmidt AC, Murphy BR, Pickles RJ. Growth restriction of an experimental live attenuated human parainfluenza virus type 2 vaccine in human ciliated airway epithelium in vitro parallels attenuation in African green monkeys. Vaccine. 28: 2788-98. PMID 20139039 DOI: 10.1016/J.Vaccine.2010.01.050  0.694
2010 Schaap-Nutt A, D'Angelo C, Scull MA, Amaro-Carambot E, Nishio M, Pickles RJ, Collins PL, Murphy BR, Schmidt AC. Human parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates. Virology. 397: 285-98. PMID 19969320 DOI: 10.1016/J.Virol.2009.11.018  0.678
2009 Ayora-Talavera G, Shelton H, Scull MA, Ren J, Jones IM, Pickles RJ, Barclay WS. Mutations in H5N1 influenza virus hemagglutinin that confer binding to human tracheal airway epithelium. Plos One. 4: e7836. PMID 19924306 DOI: 10.1371/Journal.Pone.0007836  0.697
2009 Scull MA, Gillim-Ross L, Santos C, Roberts KL, Bordonali E, Subbarao K, Barclay WS, Pickles RJ. Avian Influenza virus glycoproteins restrict virus replication and spread through human airway epithelium at temperatures of the proximal airways. Plos Pathogens. 5: e1000424. PMID 19436701 DOI: 10.1371/Journal.Ppat.1000424  0.709
2009 Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, Guthrie EH, Pickles RJ, Ting JP. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 30: 556-65. PMID 19362020 DOI: 10.1016/J.Immuni.2009.02.005  0.704
2009 Kesimer M, Scull M, Brighton B, DeMaria G, Burns K, O'Neal W, Pickles RJ, Sheehan JK. Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1858-68. PMID 19190083 DOI: 10.1096/Fj.08-119131  0.621
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