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Jennifer V. Hines - Publications

Affiliations: 
Chemistry & Biochemistry Ohio University, Athens, OH, United States 
Area:
Biochemistry
Website:
https://www.ohio.edu/cas/chemistry/contact/profiles.cfm?profile=hinesj
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hossain MI, Myers M, Herath D, Aldhumani AH, Boesger H, Hines JV. 4-Aminoquinolines modulate RNA structure and function: Pharmacophore implications of a conformationally restricted polyamine. Biochemical and Biophysical Research Communications. 644: 55-61. PMID 36630735 DOI: 10.1016/j.bbrc.2022.12.080  0.574
2021 Ghazanfari D, Noori MS, Bergmeier SC, Hines JV, McCall KD, Goetz DJ. A novel GSK-3 inhibitor binds to GSK-3β via a reversible, time and Cys-199-dependent mechanism. Bioorganic & Medicinal Chemistry. 40: 116179. PMID 33991821 DOI: 10.1016/j.bmc.2021.116179  0.536
2021 Shriwas P, Roberts D, Li Y, Wang L, Qian Y, Bergmeier S, Hines J, Adhicary S, Nielsen C, Chen X. A small-molecule pan-class I glucose transporter inhibitor reduces cancer cell proliferation in vitro and tumor growth in vivo by targeting glucose-based metabolism. Cancer & Metabolism. 9: 14. PMID 33771231 DOI: 10.1186/s40170-021-00248-7  0.495
2021 Aldhumani AH, Hossain MI, Fairchild EA, Boesger H, Marino EC, Myers M, Hines JV. RNA sequence and ligand binding alter conformational profile of SARS-CoV-2 stem loop II motif. Biochemical and Biophysical Research Communications. 545: 75-80. PMID 33545635 DOI: 10.1016/j.bbrc.2021.01.013  0.459
2020 Armstrong I, Aldhumani AH, Schopis JL, Fang F, Parsons E, Zeng C, Hossain MI, Bergmeier SC, Hines JV. RNA drug discovery: Conformational restriction enhances specific modulation of the T-box riboswitch function. Bioorganic & Medicinal Chemistry. 28: 115696. PMID 33069065 DOI: 10.1016/J.Bmc.2020.115696  0.761
2019 Murphy ER, Roβmanith J, Sieg J, Fris ME, Hussein H, Kouse AB, Gross K, Zeng C, Hines JV, Narberhaus F, Coschigano PW. Regulation of OmpA translation and virulence by an RNA thermometer. Infection and Immunity. PMID 31792074 DOI: 10.1128/Iai.00871-19  0.578
2015 Liu J, Zeng C, Hogan V, Zhou S, Monwar MM, Hines JV. Identification of Spermidine Binding Site in T-box Riboswitch Antiterminator RNA. Chemical Biology & Drug Design. PMID 26348362 DOI: 10.1111/Cbdd.12660  0.696
2015 Zeng C, Zhou S, Bergmeier SC, Hines JV. Factors that influence T box riboswitch efficacy and tRNA affinity. Bioorganic & Medicinal Chemistry. 23: 5702-8. PMID 26220520 DOI: 10.1016/J.Bmc.2015.07.018  0.737
2015 Liu J, Zeng C, Zhou S, Means JA, Hines JV. Fluorescence assays for monitoring RNA-ligand interactions and riboswitch-targeted drug discovery screening. Methods in Enzymology. 550: 363-83. PMID 25605395 DOI: 10.1016/Bs.Mie.2014.10.040  0.766
2015 Zhou S, Anupam R, Hines JV. Fluorescence anisotropy: analysis of tRNA binding to the T box riboswitch antiterminator RNA. Methods in Molecular Biology (Clifton, N.J.). 1240: 143-52. PMID 25352143 DOI: 10.1007/978-1-4939-1896-6_11  0.842
2015 Anupam R, Zhou S, Hines JV. Electrophoretic mobility shift assays: analysis of tRNA binding to the T box riboswitch antiterminator RNA. Methods in Molecular Biology (Clifton, N.J.). 1240: 135-42. PMID 25352142 DOI: 10.1007/978-1-4939-1896-6_10  0.847
2012 Liu Y, Cao Y, Zhang W, Bergmeier S, Qian Y, Akbar H, Colvin R, Ding J, Tong L, Wu S, Hines J, Chen X. A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo Molecular Cancer Therapeutics. 11: 1672-1682. PMID 22689530 DOI: 10.1158/1535-7163.Mct-12-0131  0.551
2012 Jentzsch F, Hines JV. Interfacing medicinal chemistry with structural bioinformatics: implications for T box riboswitch RNA drug discovery. Bmc Bioinformatics. 13: S5. PMID 22536868 DOI: 10.1186/1471-2105-13-S2-S5  0.507
2012 Fang F, Vogel M, Hines JV, Bergmeier SC. Fused ring aziridines as a facile entry into triazole fused tricyclic and bicyclic heterocycles. Organic & Biomolecular Chemistry. 10: 3080-91. PMID 22402729 DOI: 10.1039/C2Ob07042A  0.596
2012 Zhou S, Means JA, Acquaah-Harrison G, Bergmeier SC, Hines JV. Characterization of a 1,4-disubstituted 1,2,3-triazole binding to T box antiterminator RNA. Bioorganic & Medicinal Chemistry. 20: 1298-302. PMID 22230198 DOI: 10.1016/J.Bmc.2011.12.017  0.867
2012 Zhou S, Acquaah-Harrison G, Jack KD, Bergmeier SC, Hines JV. Ligand-induced changes in T box antiterminator RNA stability. Chemical Biology & Drug Design. 79: 202-8. PMID 22117759 DOI: 10.1111/J.1747-0285.2011.01274.X  0.821
2012 Liu Y, Cao Y, Zhang W, Bergmeier S, Qian Y, Akbar H, Colvin R, Ding J, Tong L, Wu S, Hines J, Chen X. Abstract 3231: A small molecule inhibitor of glucose transporter 1 (Glut1) down-regulates glycolysis, induces cell cycle arrest, and inhibits cancer cell growthin vitroandin vivo Cancer Research. 72: 3231-3231. DOI: 10.1158/1538-7445.Am2012-3231  0.553
2012 Bergmeier S, Maciagiewicz I, Fang F, Roberts D, Zhou S, Hines J. A Synthesis of 1,4-Disubstituted Imidazolidin-2-ones from Fused-Ring Aziridines Synthesis. 2012: 551-560. DOI: 10.1055/S-0031-1289684  0.54
2012 Maciagiewicz IM, Fang F, Roberts DA, Zhou S, Hines JV, Bergmeier SC. ChemInform Abstract: A Synthesis of 1,4-Disubstituted Imidazolidin-2-ones from Fused-Ring Aziridines. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201224120  0.491
2011 Zhou S, Acquaah-Harrison G, Bergmeier SC, Hines JV. Anisotropy studies of tRNA-T box antiterminator RNA complex in the presence of 1,4-disubstituted 1,2,3-triazoles. Bioorganic & Medicinal Chemistry Letters. 21: 7059-63. PMID 22001091 DOI: 10.1016/J.Bmcl.2011.09.095  0.792
2011 Orac CM, Zhou S, Means JA, Boehm D, Bergmeier SC, Hines JV. Synthesis and stereospecificity of 4,5-disubstituted oxazolidinone ligands binding to T-box riboswitch RNA. Journal of Medicinal Chemistry. 54: 6786-95. PMID 21812425 DOI: 10.1021/Jm2006904  0.841
2011 Maciagiewicz I, Zhou S, Bergmeier SC, Hines JV. Structure-activity studies of RNA-binding oxazolidinone derivatives. Bioorganic & Medicinal Chemistry Letters. 21: 4524-7. PMID 21733684 DOI: 10.1016/J.Bmcl.2011.05.130  0.758
2010 Acquaah-Harrison G, Zhou S, Hines JV, Bergmeier SC. Library of 1,4-disubstituted 1,2,3-triazole analogs of oxazolidinone RNA-binding agents. Journal of Combinatorial Chemistry. 12: 491-6. PMID 20557032 DOI: 10.1021/Cc100029Y  0.77
2010 Hines J, Means JA, Muchenditsi A, Agyeman A. Structural Probing of the T Box Antiterminator-tRNA Complex Biophysical Journal. 98: 263a. DOI: 10.1016/J.Bpj.2009.12.1434  0.792
2009 Means JA, Simson CM, Zhou S, Rachford AA, Rack JJ, Hines JV. Fluorescence probing of T box antiterminator RNA: insights into riboswitch discernment of the tRNA discriminator base. Biochemical and Biophysical Research Communications. 389: 616-21. PMID 19755116 DOI: 10.1016/J.Bbrc.2009.09.037  0.811
2009 Fauzi H, Agyeman A, Hines JV. T box transcription antitermination riboswitch: influence of nucleotide sequence and orientation on tRNA binding by the antiterminator element. Biochimica Et Biophysica Acta. 1789: 185-91. PMID 19152843 DOI: 10.1016/J.Bbagrm.2008.12.004  0.777
2008 Anupam R, Nayek A, Green NJ, Grundy FJ, Henkin TM, Means JA, Bergmeier SC, Hines JV. 4,5-Disubstituted oxazolidinones: High affinity molecular effectors of RNA function. Bioorganic & Medicinal Chemistry Letters. 18: 3541-4. PMID 18502126 DOI: 10.1016/J.Bmcl.2008.05.015  0.822
2008 Jack KD, Means JA, Hines JV. Characterizing riboswitch function: identification of Mg2+ binding site in T box antiterminator RNA. Biochemical and Biophysical Research Communications. 370: 306-10. PMID 18371302 DOI: 10.1016/J.Bbrc.2008.03.079  0.804
2008 Anupam R, Denapoli L, Muchenditsi A, Hines JV. Identification of neomycin B-binding site in T box antiterminator model RNA. Bioorganic & Medicinal Chemistry. 16: 4466-70. PMID 18329274 DOI: 10.1016/J.Bmc.2008.02.056  0.827
2007 Means JA, Wolf S, Agyeman A, Burton JS, Simson CM, Hines JV. T box riboswitch antiterminator affinity modulated by tRNA structural elements. Chemical Biology & Drug Design. 69: 139-45. PMID 17381728 DOI: 10.1111/J.1747-0285.2007.00476.X  0.859
2006 Means J, Katz S, Nayek A, Anupam R, Hines JV, Bergmeier SC. Structure-activity studies of oxazolidinone analogs as RNA-binding agents. Bioorganic & Medicinal Chemistry Letters. 16: 3600-4. PMID 16603349 DOI: 10.1016/J.Bmcl.2006.03.068  0.831
2005 Fauzi H, Jack KD, Hines JV. In vitro selection to identify determinants in tRNA for Bacillus subtilis tyrS T box antiterminator mRNA binding. Nucleic Acids Research. 33: 2595-602. PMID 15879350 DOI: 10.1093/Nar/Gki546  0.842
2005 Means JA, Hines JV. Fluorescence resonance energy transfer studies of aminoglycoside binding to a T box antiterminator RNA. Bioorganic & Medicinal Chemistry Letters. 15: 2169-72. PMID 15808490 DOI: 10.1016/J.Bmcl.2005.02.007  0.834
2003 Gerdeman MS, Henkin TM, Hines JV. Solution structure of the Bacillus subtilis T-box antiterminator RNA: Seven nucleotide bulge characterized by stacking and flexibility Journal of Molecular Biology. 326: 189-201. PMID 12547201 DOI: 10.1016/S0022-2836(02)01339-6  0.578
2002 Donaldson SF, Bergmeier SC, Hines JV, Gerdeman MS. Synthesis and hybridization studies of a 5-aminopentanoic acid nucleobase (APN) dimer. Nucleosides, Nucleotides & Nucleic Acids. 21: 111-23. PMID 11991139 DOI: 10.1081/Ncn-120003176  0.559
2002 Gerdeman MS, Henkin TM, Hines JV. In vitro structure-function studies of the Bacillus subtilis tyrS mRNA antiterminator: Evidence for factor-independent tRNA acceptor stem binding specificity Nucleic Acids Research. 30: 1065-1072. PMID 11842119 DOI: 10.1093/Nar/30.4.1065  0.664
2000 Pearson WH, Hines JV. Total syntheses of (+)-australine and (-)-7-epialexine. The Journal of Organic Chemistry. 65: 5785-93. PMID 10970325 DOI: 10.1021/Jo000689Q  0.529
1996 Kang H, Hines JV, Tinoco I. Conformation of a non-frameshifting RNA pseudoknot from mouse mammary tumor virus. Journal of Molecular Biology. 259: 135-47. PMID 8648641 DOI: 10.1006/Jmbi.1996.0308  0.385
1995 Chen X, Chamorro M, Lee SI, Shen LX, Hines JV, Tinoco I, Varmus HE. Structural and functional studies of retroviral RNA pseudoknots involved in ribosomal frameshifting: nucleotides at the junction of the two stems are important for efficient ribosomal frameshifting. The Embo Journal. 14: 842-52. PMID 7882986  0.385
1991 Pearson WH, Hines JV. A synthesis of (+)-7-Epiaustraline and (-)-7-Epialexine Tetrahedron Letters. 32: 5513-5516. DOI: 10.1016/0040-4039(91)80071-D  0.472
1989 Pearson WH, Hines JV. Synthesis of .beta.-amino-.alpha.-hydroxy acids via aldol condensation of a chiral glycolate enolate. A synthesis of (-)-bestatin The Journal of Organic Chemistry. 54: 4235-4237. DOI: 10.1021/jo00278a050  0.451
1989 Pearson WH, Hines JV. Synthesis of β-amino-α-hydroxy acids via aldol condensation of a chiral glycolate enolate. Synthesis of (-)-bestatin Journal of Organic Chemistry. 54: 4235-4237.  0.456
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