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Pamela L. Schwartzberg - Publications

Affiliations: 
Biomedical Sciences The George Washington University, Washington, DC, United States 
Area:
Immunology, Biochemistry
Website:
https://www.genome.gov/10001130/schwartzberg--group/
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Preite S, Gomez-Rodriguez J, Cannons JL, Schwartzberg PL. T and B-cell signaling in activated PI3K delta syndrome: From immunodeficiency to autoimmunity. Immunological Reviews. 291: 154-173. PMID 31402502 DOI: 10.1111/imr.12790  0.341
2018 Preite S, Huang B, Cannons JL, McGavern DB, Schwartzberg PL. PI3K Orchestrates T Follicular Helper Cell Differentiation in a Context Dependent Manner: Implications for Autoimmunity. Frontiers in Immunology. 9: 3079. PMID 30666254 DOI: 10.3389/Fimmu.2018.03079  0.334
2018 Cannons JL, Preite S, Kapnick SM, Uzel G, Schwartzberg PL. Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8 T Cell Survival, Differentiation, and Function. Frontiers in Immunology. 9: 1758. PMID 30116245 DOI: 10.3389/fimmu.2018.01758  0.352
2017 Kapnick SM, Stinchcombe JC, Griffiths GM, Schwartzberg PL. Inducible T Cell Kinase Regulates the Acquisition of Cytolytic Capacity and Degranulation in CD8(+) CTLs. Journal of Immunology (Baltimore, Md. : 1950). PMID 28213500 DOI: 10.4049/jimmunol.1601202  0.317
2016 Huang B, Gomez-Rodriguez J, Preite S, Garrett LJ, Harper UL, Schwartzberg PL. CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development. Plos One. 11: e0156072. PMID 27258160 DOI: 10.1371/journal.pone.0156072  0.355
2016 Ruffo E, Malacarne V, Larsen SE, Das R, Patrussi L, Wülfing C, Biskup C, Kapnick SM, Verbist K, Tedrick P, Schwartzberg PL, Baldari CT, Rubio I, Nichols KE, Snow AL, et al. Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1. Science Translational Medicine. 8: 321ra7. PMID 26764158 DOI: 10.1126/Scitranslmed.Aad1565  0.335
2014 Lucas CL, Kuehn HS, Zhao F, Niemela JE, Deenick EK, Palendira U, Avery DT, Moens L, Cannons JL, Biancalana M, Stoddard J, Ouyang W, Frucht DM, Rao VK, Atkinson TP, ... ... Schwartzberg PL, et al. Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency. Nature Immunology. 15: 88-97. PMID 24165795 DOI: 10.1038/Ni.2771  0.371
2012 Zhao F, Cannons JL, Dutta M, Griffiths GM, Schwartzberg PL. Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis. Immunity. 36: 1003-16. PMID 22683123 DOI: 10.1016/j.immuni.2012.05.017  0.315
2011 Zhang S, Readinger JA, DuBois W, Janka-Junttila M, Robinson R, Pruitt M, Bliskovsky V, Wu JZ, Sakakibara K, Patel J, Parent CA, Tessarollo L, Schwartzberg PL, Mock BA. Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production. Blood. 117: 1228-38. PMID 21079150 DOI: 10.1182/blood-2010-05-287821  0.307
2010 Andreotti AH, Schwartzberg PL, Joseph RE, Berg LJ. T-cell signaling regulated by the Tec family kinase, Itk. Cold Spring Harbor Perspectives in Biology. 2: a002287. PMID 20519342 DOI: 10.1101/Cshperspect.A002287  0.303
2009 Rumble JM, Oetjen KA, Stein PL, Schwartzberg PL, Moore BB, Duckett CS. Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP). Cellular Immunology. 259: 82-9. PMID 19595300 DOI: 10.1016/J.Cellimm.2009.05.017  0.32
2009 Chiang YJ, Jordan MS, Horai R, Schwartzberg PL, Koretzky GA, Hodes RJ. Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation. The Journal of Biological Chemistry. 284: 4429-38. PMID 19074136 DOI: 10.1074/Jbc.M808679200  0.35
2006 Kamperschroer C, Dibble JP, Meents DL, Schwartzberg PL, Swain SL. SAP is required for Th cell function and for immunity to influenza. Journal of Immunology (Baltimore, Md. : 1950). 177: 5317-27. PMID 17015717  0.302
2006 Watford WT, Li D, Agnello D, Durant L, Yamaoka K, Yao ZJ, Ahn HJ, Cheng TP, Hofmann SR, Cogliati T, Chen A, Hissong BD, Husa MR, Schwartzberg P, O'Shea JJ, et al. Cytohesin binder and regulator (cybr) is not essential for T- and dendritic-cell activation and differentiation. Molecular and Cellular Biology. 26: 6623-32. PMID 16914744 DOI: 10.1128/Mcb.02460-05  0.318
2006 Cannons JL, Yu LJ, Jankovic D, Crotty S, Horai R, Kirby M, Anderson S, Cheever AW, Sher A, Schwartzberg PL. SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation. The Journal of Experimental Medicine. 203: 1551-65. PMID 16754717 DOI: 10.1084/Jem.20052097  0.347
2006 Jordan MS, Sadler J, Austin JE, Finkelstein LD, Singer AL, Schwartzberg PL, Koretzky GA. Functional hierarchy of the N-terminal tyrosines of SLP-76. Journal of Immunology (Baltimore, Md. : 1950). 176: 2430-8. PMID 16456002 DOI: 10.4049/Jimmunol.176.4.2430  0.339
2005 Schwartzberg PL, Finkelstein LD, Readinger JA. TEC-family kinases: regulators of T-helper-cell differentiation. Nature Reviews. Immunology. 5: 284-95. PMID 15803148 DOI: 10.1038/nri1591  0.308
2005 Berg LJ, Finkelstein LD, Lucas JA, Schwartzberg PL. Tec family kinases in T lymphocyte development and function. Annual Review of Immunology. 23: 549-600. PMID 15771581 DOI: 10.1146/Annurev.Immunol.22.012703.104743  0.305
2005 Nichols KE, Hom J, Gong SY, Ganguly A, Ma CS, Cannons JL, Tangye SG, Schwartzberg PL, Koretzky GA, Stein PL. Regulation of NKT cell development by SAP, the protein defective in XLP. Nature Medicine. 11: 340-5. PMID 15711562 DOI: 10.1038/Nm1189  0.332
2004 Cannons JL, Yu LJ, Hill B, Mijares LA, Dombroski D, Nichols KE, Antonellis A, Koretzky GA, Gardner K, Schwartzberg PL. SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1. Immunity. 21: 693-706. PMID 15539155 DOI: 10.1016/J.Immuni.2004.09.012  0.592
2004 Takesono A, Horai R, Mandai M, Dombroski D, Schwartzberg PL. Requirement for Tec kinases in chemokine-induced migration and activation of Cdc42 and Rac. Current Biology : Cb. 14: 917-22. PMID 15186750 DOI: 10.1016/j.cub.2004.04.011  0.302
2004 Zhao L, Cannons JL, Castilla LH, Schwartzberg PL, Liu PP. The Role of CBFβ in T Cell Development. Blood. 104: 3234-3234. DOI: 10.1182/Blood.V104.11.3234.3234  0.328
2004 Nichols KE, Hom J, Ganguly A, Ma CS, Tangye SG, Cannons JL, Schwartzberg PL, Koretzky GA, Stein PL. Regulation of NKT Cell Development by Sap, the Adaptor Mutated in X-Linked Lymphoproliferative Disease. Blood. 104: 317-317. DOI: 10.1182/Blood.V104.11.317.317  0.342
2003 Schwartzberg PL. Genetic approaches to tyrosine kinase signaling pathways in the immune system. Immunologic Research. 27: 481-8. PMID 12857991 DOI: 10.1385/IR:27:2-3:481  0.31
2001 Schaeffer EM, Yap GS, Lewis CM, Czar MJ, McVicar DW, Cheever AW, Sher A, Schwartzberg PL. Mutation of Tec family kinases alters T helper cell differentiation. Nature Immunology. 2: 1183-8. PMID 11702066 DOI: 10.1038/Ni734  0.332
2001 Czar MJ, Kersh EN, Mijares LA, Lanier G, Lewis J, Yap G, Chen A, Sher A, Duckett CS, Ahmed R, Schwartzberg PL. Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP Proceedings of the National Academy of Sciences of the United States of America. 98: 7449-7454. PMID 11404475 DOI: 10.1073/Pnas.131193098  0.315
2001 Chamorro M, Czar MJ, Debnath J, Cheng G, Lenardo MJ, Varmus HE, Schwartzberg PL. Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk. Bmc Immunology. 2: 3. PMID 11353545 DOI: 10.1186/1471-2172-2-3  0.472
2001 Xing L, Venegas AM, Chen A, Garrett-Beal L, Boyce BF, Varmus HE, Schwartzberg PL. Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival. Genes & Development. 15: 241-53. PMID 11157779 DOI: 10.1101/Gad.840301  0.479
2000 Schaeffer EM, Broussard C, Debnath J, Anderson S, McVicar DW, Schwartzberg PL. Tec family kinases modulate thresholds for thymocyte development and selection Journal of Experimental Medicine. 192: 987-1000. PMID 11015440 DOI: 10.1084/Jem.192.7.987  0.328
2000 Schaeffer EM, Schwartzberg PL. Tec family kinases in lymphocyte signaling and function Current Opinion in Immunology. 12: 282-288. PMID 10781397 DOI: 10.1016/S0952-7915(00)00088-1  0.333
2000 Sun Z, Arendt CW, Ellmeier W, Schaeffer EM, Sunshine MJ, Gandhi L, Annes J, Petrzilka D, Kupfer A, Schwartzberg PL, Littman DR. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. Nature. 404: 402-7. PMID 10746729 DOI: 10.1038/35006090  0.314
1999 Schaeffer EM, Debnath J, Yap G, McVicar D, Liao XC, Littman DR, Sher A, Varmus HE, Lenardo MJ, Schwartzberg PL. Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science (New York, N.Y.). 284: 638-41. PMID 10213685 DOI: 10.1126/Science.284.5414.638  0.496
1999 Debnath J, Chamorro M, Czar MJ, Schaeffer EM, Lenardo MJ, Varmus HE, Schwartzberg PL. rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases. Molecular and Cellular Biology. 19: 1498-507. PMID 9891083 DOI: 10.1128/Mcb.19.2.1498  0.47
1998 Schwartzberg PL. The many faces of Src: Multiple functions of a prototypical tyrosine kinase Oncogene. 17: 1463-1468. PMID 9779992  0.305
1997 Schwartzberg PL, Xing L, Hoffmann O, Lowell CA, Garrett L, Boyce BF, Varmus HE. Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice. Genes & Development. 11: 2835-44. PMID 9353253 DOI: 10.1101/Gad.11.21.2835  0.528
1996 Hardin JD, Boast S, Schwartzberg PL, Lee G, Alt FW, Stall AM, Goff SP. Abnormal peripheral lymphocyte function in c-abl mutant mice. Cellular Immunology. 172: 100-7. PMID 8806812 DOI: 10.1006/Cimm.1996.0220  0.591
1995 Hu Q, Davidson D, Schwartzberg PL, Macchiarini F, Lenardo MJ, Bluestone JA, Matis LA. Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage Journal of Biological Chemistry. 270: 1928-1934. PMID 7829530 DOI: 10.1074/Jbc.270.4.1928  0.315
1995 Hardin JD, Boast S, Schwartzberg PL, Lee G, Alt FW, Stall AM, Goff SP. Bone marrow B lymphocyte development in c-abl-deficient mice. Cellular Immunology. 165: 44-54. PMID 7671324 DOI: 10.1006/Cimm.1995.1185  0.566
1993 Schwartzberg PL, Roth MJ, Tanese N, Goff SP. Analysis of a temperature-sensitive mutation affecting the integration protein of Moloney murine leukemia virus. Virology. 192: 673-8. PMID 8421906 DOI: 10.1006/Viro.1993.1086  0.562
1991 Schwartzberg PL, Stall AM, Hardin JD, Bowdish KS, Humaran T, Boast S, Harbison ML, Robertson EJ, Goff SP. Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations Cell. 65: 1165-1175. PMID 2065353 DOI: 10.1016/0092-8674(91)90012-N  0.615
1990 Roth MJ, Schwartzberg P, Tanese N, Goff SP. Analysis of mutations in the integration function of Moloney murine leukemia virus: effects on DNA binding and cutting. Journal of Virology. 64: 4709-17. PMID 2204722 DOI: 10.1128/Jvi.64.10.4709-4717.1990  0.567
1990 Schwartzberg PL, Robertson EJ, Goff SP. Targeted gene disruption of the endogenous c-abl locus by homologous recombination with DNA encoding a selectable fusion protein Proceedings of the National Academy of Sciences of the United States of America. 87: 3210-3214. PMID 2183226 DOI: 10.1073/Pnas.87.8.3210  0.557
1989 Schwartzberg PL, Goff SP, Robertson EJ. Germ-like transmission of a c-abl mutation produced by targeted gene disruption in ES cells Science. 246: 799-803. PMID 2554496 DOI: 10.1126/Science.2554496  0.583
1989 Roth MJ, Schwartzberg PL, Goff SP. Structure of the termini of DNA intermediates in the integration of retroviral DNA: Dependence on IN function and terminal DNA sequence Cell. 58: 47-54. PMID 2546673 DOI: 10.1016/0092-8674(89)90401-7  0.505
1985 Schwartzberg P, Colicelli J, Goff SP. Recombination between a defective retrovirus and homologous sequences in host DNA: reversion by patch repair. Journal of Virology. 53: 719-26. PMID 2983084 DOI: 10.1128/Jvi.53.3.719-726.1985  0.568
1985 Hsu HW, Schwartzberg P, Goff SP. Point mutations in the P30 domain of the gag gene of Moloney murine leukemia virus. Virology. 142: 211-4. PMID 2414902 DOI: 10.1016/0042-6822(85)90435-0  0.591
1984 Schwartzberg P, Colicelli J, Goff SP. Construction and analysis of deletion mutations in the pol gene of Moloney murine leukemia virus: a new viral function required for productive infection. Cell. 37: 1043-52. PMID 6204767 DOI: 10.1016/0092-8674(84)90439-2  0.592
1984 Schwartzberg P, Colicelli J, Gordon ML, Goff SP. Mutations in the gag gene of Moloney murine leukemia virus: effects on production of virions and reverse transcriptase. Journal of Virology. 49: 918-24. PMID 6199513 DOI: 10.1128/Jvi.49.3.918-924.1984  0.548
1983 Schwartzberg P, Colicelli J, Goff SP. Deletion mutants of Moloney murine leukemia virus which lack glycosylated gag protein are replication competent. Journal of Virology. 46: 538-46. PMID 6601726 DOI: 10.1128/Jvi.46.2.538-546.1983  0.581
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