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Tony Hunter - Publications

Salk Institute for Biological Studies, La Jolla, CA, United States 
growth control and cell cycle regulation

410 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hunter T. A journey from phosphotyrosine to phosphohistidine and beyond. Molecular Cell. 82: 2190-2200. PMID 35654043 DOI: 10.1016/j.molcel.2022.05.007  0.335
2021 Hara T, Chanoch-Myers R, Mathewson ND, Myskiw C, Atta L, Bussema L, Eichhorn SW, Greenwald AC, Kinker GS, Rodman C, Gonzalez Castro LN, Wakimoto H, Rozenblatt-Rosen O, Zhuang X, Fan J, ... Hunter T, et al. Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma. Cancer Cell. PMID 34087162 DOI: 10.1016/j.ccell.2021.05.002  0.42
2020 Adam K, Ning J, Reina J, Hunter T. NME/NM23/NDPK and Histidine Phosphorylation. International Journal of Molecular Sciences. 21. PMID 32823988 DOI: 10.3390/Ijms21165848  0.412
2020 Ogawa J, Zhu W, Tonnu N, Singer O, Hunter T, Ryan AL, Pao GM. The D614G mutation in the SARS-CoV2 Spike protein increases infectivity in an ACE2 receptor dependent manner. Biorxiv : the Preprint Server For Biology. PMID 32743569 DOI: 10.1101/2020.07.21.214932  0.718
2020 Adam K, Lesperance J, Hunter T, Zage PE. The Potential Functional Roles of NME1 Histidine Kinase Activity in Neuroblastoma Pathogenesis. International Journal of Molecular Sciences. 21. PMID 32392889 DOI: 10.3390/Ijms21093319  0.391
2020 Adam K, Hunter T. Subcellular Localization of Histidine Phosphorylated Proteins Through Indirect Immunofluorescence. Methods in Molecular Biology (Clifton, N.J.). 2077: 209-224. PMID 31707661 DOI: 10.1007/978-1-4939-9884-5_14  0.38
2020 Luhtala N, Hunter T. Immunohistochemistry (IHC): Chromogenic Detection of 3-Phosphohistidine Proteins in Formaldehyde-Fixed, Frozen Mouse Liver Tissue Sections. Methods in Molecular Biology (Clifton, N.J.). 2077: 193-208. PMID 31707660 DOI: 10.1007/978-1-4939-9884-5_13  0.341
2020 Kalagiri R, Adam K, Hunter T. Empirical Evidence of Cellular Histidine Phosphorylation by Immunoblotting Using pHis mAbs. Methods in Molecular Biology (Clifton, N.J.). 2077: 181-191. PMID 31707659 DOI: 10.1007/978-1-4939-9884-5_12  0.349
2019 Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, ... ... Hunter T, et al. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. PMID 31327527 DOI: 10.1016/J.Cell.2019.06.024  0.468
2018 Chou AC, Aslanian A, Sun H, Hunter T. An internal ribosome entry site in the coding region of tyrosyl-DNA phosphodiesterase 2 drives alternative translation start. The Journal of Biological Chemistry. PMID 30593505 DOI: 10.1074/Jbc.Ra118.006269  0.402
2018 Lamarche BJ, Orazio NI, Goben B, Meisenhelder J, You Z, Weitzman MD, Hunter T. Repair of protein-linked DNA double strand breaks: Using the adenovirus genome as a model substrate in cell-based assays. Dna Repair. PMID 30583959 DOI: 10.1016/J.Dnarep.2018.12.001  0.355
2018 Luhtala N, Hunter T. Failure to detect functional transfer of active K-Ras protein from extracellular vesicles into recipient cells in culture. Plos One. 13: e0203290. PMID 30192821 DOI: 10.1371/Journal.Pone.0203290  0.303
2018 Chu B, He A, Tian Y, He W, Chen P, Hu J, Xu R, Zhou W, Zhang M, Yang P, Li SSC, Sun Y, Li P, Hunter T, Tian R. Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples. Proceedings of the National Academy of Sciences of the United States of America. PMID 30190427 DOI: 10.1073/Pnas.1805633115  0.366
2018 Zhu Q, Hoong N, Aslanian A, Hara T, Benner C, Heinz S, Miga KH, Ke E, Verma S, Soroczynski J, Yates JR, Hunter T, Verma IM. Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer. Molecular Cell. PMID 29861157 DOI: 10.1016/J.Molcel.2018.04.023  0.471
2018 Hindupur SK, Colombi M, Fuhs SR, Matter MS, Guri Y, Adam K, Cornu M, Piscuoglio S, Ng CKY, Betz C, Liko D, Quagliata L, Moes S, Jenoe P, Terracciano LM, ... ... Hunter T, et al. The protein histidine phosphatase LHPP is a tumour suppressor. Nature. PMID 29562234 DOI: 10.1038/Nature26140  0.362
2018 Hsu CL, Lee EX, Gordon KL, Paz EA, Shen WC, Ohnishi K, Meisenhelder J, Hunter T, La Spada AR. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nature Communications. 9: 942. PMID 29507340 DOI: 10.1038/S41467-018-03340-7  0.394
2018 Lu Z, Hunter T. Metabolic Kinases Moonlighting as Protein Kinases. Trends in Biochemical Sciences. PMID 29463470 DOI: 10.1016/J.Tibs.2018.01.006  0.437
2017 Adam K, Hunter T. Histidine kinases and the missing phosphoproteome from prokaryotes to eukaryotes. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29058706 DOI: 10.1038/Labinvest.2017.118  0.453
2017 Hoppmann C, Wong A, Yang B, Li S, Hunter T, Shokat KM, Wang L. Site-specific incorporation of phosphotyrosine using an expanded genetic code. Nature Chemical Biology. PMID 28604697 DOI: 10.1038/Nchembio.2406  0.417
2017 Fuhs SR, Hunter T. pHisphorylation: the emergence of histidine phosphorylation as a reversible regulatory modification. Current Opinion in Cell Biology. 45: 8-16. PMID 28129587 DOI: 10.1016/J.Ceb.2016.12.010  0.389
2016 Luhtala N, Aslanian A, Yates JR, Hunter T. Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner. The Journal of Biological Chemistry. PMID 27909058 DOI: 10.1074/Jbc.M116.747618  0.311
2016 Srivastava S, Panda S, Li Z, Fuhs SR, Hunter T, Thiele DJ, Hubbard SR, Skolnik EY. Histidine phosphorylation relieves copper inhibition in the mammalian potassium channel KCa3.1. Elife. 5. PMID 27542194 DOI: 10.7554/Elife.16093  0.356
2016 Panda S, Srivastava S, Li Z, Vaeth M, Fuhs SR, Hunter T, Skolnik EY. Identification of PGAM5 as a Mammalian Protein Histidine Phosphatase that Plays a Central Role to Negatively Regulate CD4(+) T Cells. Molecular Cell. PMID 27453048 DOI: 10.1016/J.Molcel.2016.06.021  0.424
2016 Li X, Jiang Y, Meisenhelder J, Yang W, Hawke DH, Zheng Y, Xia Y, Aldape K, He J, Hunter T, Wang L, Lu Z. Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis. Molecular Cell. 61: 705-719. PMID 26942675 DOI: 10.1016/J.Molcel.2016.02.009  0.407
2016 Shi Y, Tian R, Hunter T. Abstract B27: Interdicting the cytokine-mediated paracrine communication between pancreatic cancer and stellate cells as a new treatment approach for pancreatic ductal adenocarcinoma Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B27  0.308
2015 Heimbucher T, Hunter T. The C. elegans Ortholog of USP7 controls DAF-16 stability in Insulin/IGF-1-like signaling. Worm. 4: e1103429. PMID 27123371 DOI: 10.1080/21624054.2015.1103429  0.746
2015 Marusiak AA, Stephenson NL, Baik H, Trotter EW, Li Y, Blyth K, Mason S, Chapman P, Puto LA, Read JA, Brassington C, Pollard HK, Phillips C, Green I, Overman R, ... ... Hunter T, et al. Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis. Cancer Research. PMID 26637668 DOI: 10.1158/0008-5472.Can-15-0701-T  0.359
2015 Denli AM, Narvaiza I, Kerman BE, Pena M, Benner C, Marchetto MC, Diedrich JK, Aslanian A, Ma J, Moresco JJ, Moore L, Hunter T, Saghatelian A, Gage FH. Primate-Specific ORF0 Contributes to Retrotransposon-Mediated Diversity. Cell. 163: 583-93. PMID 26496605 DOI: 10.1016/J.Cell.2015.09.025  0.338
2015 Heimbucher T, Liu Z, Bossard C, McCloskey R, Carrano AC, Riedel CG, Tanasa B, Klammt C, Fonslow BR, Riera CE, Lillemeier BF, Kemphues K, Yates JR, O'Shea C, Hunter T, et al. The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity. Cell Metabolism. 22: 151-63. PMID 26154057 DOI: 10.1016/J.Cmet.2015.06.002  0.782
2015 Fuhs SR, Meisenhelder J, Aslanian A, Ma L, Zagorska A, Stankova M, Binnie A, Al-Obeidi F, Mauger J, Lemke G, Yates JR, Hunter T. Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation. Cell. 162: 198-210. PMID 26140597 DOI: 10.1016/J.Cell.2015.05.046  0.341
2015 Hunter T. Discovering the first tyrosine kinase. Proceedings of the National Academy of Sciences of the United States of America. 112: 7877-82. PMID 26130799 DOI: 10.1073/Pnas.1508223112  0.46
2015 Tian R, Wang H, Gish GD, Petsalaki E, Pasculescu A, Shi Y, Mollenauer M, Bagshaw RD, Yosef N, Hunter T, Gingras AC, Weiss A, Pawson T. Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor. Proceedings of the National Academy of Sciences of the United States of America. 112: E1594-603. PMID 25829543 DOI: 10.1073/Pnas.1503286112  0.306
2015 Antal CE, Hudson AM, Kang E, Zanca C, Wirth C, Stephenson NL, Trotter EW, Gallegos LL, Miller CJ, Furnari FB, Hunter T, Brognard J, Newton AC. Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor. Cell. 160: 489-502. PMID 25619690 DOI: 10.1016/J.Cell.2015.01.001  0.351
2015 Wilkinson DS, Jariwala JS, Anderson E, Mitra K, Meisenhelder J, Chang JT, Ideker T, Hunter T, Nizet V, Dillin A, Hansen M. Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy. Molecular Cell. 57: 55-68. PMID 25544559 DOI: 10.1016/J.Molcel.2014.11.019  0.638
2015 Puto LA, Benner C, Hunter T. Abstract A1-02: Chip-Seq and RNA-Seq studies reveal novel insights into the interactive and transcriptomic architecture of the human prostate cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A1-02  0.306
2015 Antal CE, Hudson AM, Kang E, Zanca C, Wirth C, Stephenson NL, Trotter EW, Gallegos LL, Miller C, Furnari F, Hunter T, Brognard J, Newton AC. Abstract 125: Protein kinase C loss-of-function mutations in cancer reveal role as tumor suppressor Cancer Research. 75: 125-125. DOI: 10.1158/1538-7445.Am2015-125  0.35
2015 Hunter T, Manning G. The eukaryotic protein kinase superfamily and the emergence of receptor tyrosine kinases Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease. 1-15. DOI: 10.1007/978-1-4939-2053-2_1  0.61
2014 Thorner J, Hunter T, Cantley LC, Sever R. Signal transduction: From the atomic age to the post-genomic era. Cold Spring Harbor Perspectives in Biology. 6: a022913. PMID 25359498 DOI: 10.1101/Cshperspect.A022913  0.303
2014 Basnet H, Su XB, Tan Y, Meisenhelder J, Merkurjev D, Ohgi KA, Hunter T, Pillus L, Rosenfeld MG. Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation. Nature. 516: 267-71. PMID 25252977 DOI: 10.1038/Nature13736  0.398
2014 Lu Z, Hunter T. Prolyl isomerase Pin1 in cancer. Cell Research. 24: 1033-49. PMID 25124924 DOI: 10.1038/Cr.2014.109  0.451
2014 Zheng X, Hunter T. Pink1, the first ubiquitin kinase. The Embo Journal. 33: 1621-3. PMID 24942162 DOI: 10.15252/Embj.201489185  0.388
2014 Sun H, Liu Y, Hunter T. Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control. Molecular and Cellular Biology. 34: 2981-95. PMID 24912682 DOI: 10.1128/Mcb.00036-14  0.357
2014 Carrano AC, Dillin A, Hunter T. A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans. Nature Communications. 5: 3772. PMID 24805825 DOI: 10.1038/Ncomms4772  0.585
2014 Ma L, Aslanian A, Sun H, Jin M, Shi Y, Yates JR, Hunter T. Identification of small ubiquitin-like modifier substrates with diverse functions using the Xenopus egg extract system. Molecular & Cellular Proteomics : McP. 13: 1659-75. PMID 24797264 DOI: 10.1074/Mcp.M113.035626  0.358
2014 Hunter T. The genesis of tyrosine phosphorylation. Cold Spring Harbor Perspectives in Biology. 6: a020644. PMID 24789824 DOI: 10.1101/Cshperspect.A020644  0.469
2014 Aslanian A, Yates JR, Hunter T. Mass spectrometry-based quantification of the cellular response to methyl methanesulfonate treatment in human cells. Dna Repair. 15: 29-38. PMID 24461736 DOI: 10.1016/J.Dnarep.2013.12.007  0.349
2014 Ma H, Han BK, Guaderrama M, Aslanian A, Yates JR, Hunter T, Wittenberg C. Psy2 targets the PP4 family phosphatase Pph3 to dephosphorylate Mth1 and repress glucose transporter gene expression. Molecular and Cellular Biology. 34: 452-63. PMID 24277933 DOI: 10.1128/Mcb.00279-13  0.42
2014 Zhang Y, Hunter T. Roles of Chk1 in cell biology and cancer therapy. International Journal of Cancer. Journal International Du Cancer. 134: 1013-23. PMID 23613359 DOI: 10.1002/Ijc.28226  0.355
2014 Antal CE, Kang E, Stephenson NL, Trotter EW, Hunter T, Brognard J, Newton A. Abstract 5270: Prevalence of inactivating protein kinase C mutations in human cancers Cancer Research. 74: 5270-5270. DOI: 10.1158/1538-7445.Am2014-5270  0.354
2013 Hunter T. Retrospective. Tony Pawson (1952-2013). Science (New York, N.Y.). 341: 1078. PMID 24009385 DOI: 10.1126/Science.1244986  0.367
2013 Hunter T. Translating experience: thinking outside the box. Nature Cell Biology. 15: 545. PMID 23728459 DOI: 10.1038/Ncb2771  0.351
2013 Zheng X, Hunter T. Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism. Cell Research. 23: 886-97. PMID 23670163 DOI: 10.1038/Cr.2013.66  0.309
2012 Sun H, Hunter T. Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string search. The Journal of Biological Chemistry. 287: 42071-83. PMID 23086935 DOI: 10.1074/Jbc.M112.410985  0.32
2012 Zhang QC, Petrey D, Deng L, Qiang L, Shi Y, Thu CA, Bisikirska B, Lefebvre C, Accili D, Hunter T, Maniatis T, Califano A, Honig B. Structure-based prediction of protein-protein interactions on a genome-wide scale. Nature. 490: 556-60. PMID 23023127 DOI: 10.1038/Nature11503  0.303
2012 Zhu W, Kuo D, Nathanson J, Satoh A, Pao GM, Yeo GW, Bryant SV, Voss SR, Gardiner DM, Hunter T. Retrotransposon long interspersed nucleotide element-1 (LINE-1) is activated during salamander limb regeneration. Development, Growth & Differentiation. 54: 673-85. PMID 22913491 DOI: 10.1111/J.1440-169X.2012.01368.X  0.709
2012 Yang W, Xia Y, Hawke D, Li X, Liang J, Xing D, Aldape K, Hunter T, Alfred Yung WK, Lu Z. PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis. Cell. 150: 685-96. PMID 22901803 DOI: 10.1016/J.Cell.2012.07.018  0.357
2012 Hunter T. Why nature chose phosphate to modify proteins. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2513-6. PMID 22889903 DOI: 10.1098/Rstb.2012.0013  0.399
2012 Hunter T, Pawson T. The evolution of protein phosphorylation. Preface. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2512. PMID 22889902 DOI: 10.1098/Rstb.2012.0374  0.418
2012 Zhu W, Pao GM, Satoh A, Cummings G, Monaghan JR, Harkins TT, Bryant SV, Randal Voss S, Gardiner DM, Hunter T. Activation of germline-specific genes is required for limb regeneration in the Mexican axolotl. Developmental Biology. 370: 42-51. PMID 22841627 DOI: 10.1016/J.Ydbio.2012.07.021  0.712
2012 Chaurushiya MS, Lilley CE, Aslanian A, Meisenhelder J, Scott DC, Landry S, Ticau S, Boutell C, Yates JR, Schulman BA, Hunter T, Weitzman MD. Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain. Molecular Cell. 46: 79-90. PMID 22405594 DOI: 10.1016/J.Molcel.2012.02.004  0.388
2012 Hunter T, Poon RY. Cdc37: a protein kinase chaperone? Trends in Cell Biology. 7: 157-61. PMID 17708934 DOI: 10.1016/S0962-8924(97)01027-1  0.351
2011 Brognard J, Zhang YW, Puto LA, Hunter T. Cancer-associated loss-of-function mutations implicate DAPK3 as a tumor-suppressing kinase. Cancer Research. 71: 3152-61. PMID 21487036 DOI: 10.1158/0008-5472.Can-10-3543  0.363
2011 Brognard J, Hunter T. Protein kinase signaling networks in cancer. Current Opinion in Genetics & Development. 21: 4-11. PMID 21123047 DOI: 10.1016/J.Gde.2010.10.012  0.406
2010 Olson BJ, Oberholzer M, Li Y, Zones JM, Kohli HS, Bisova K, Fang SC, Meisenhelder J, Hunter T, Umen JG. Regulation of the Chlamydomonas cell cycle by a stable, chromatin-associated retinoblastoma tumor suppressor complex. The Plant Cell. 22: 3331-47. PMID 20978220 DOI: 10.1105/Tpc.110.076067  0.351
2010 Yoon YS, Lee MW, Ryu D, Kim JH, Ma H, Seo WY, Kim YN, Kim SS, Lee CH, Hunter T, Choi CS, Montminy MR, Koo SH. Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 17704-9. PMID 20876121 DOI: 10.1073/Pnas.1012665107  0.348
2010 Lu Z, Hunter T. Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitors. Cell Cycle (Georgetown, Tex.). 9: 2342-52. PMID 20519948 DOI: 10.4161/Cc.9.12.11988  0.324
2010 López-Otín C, Hunter T. The regulatory crosstalk between kinases and proteases in cancer. Nature Reviews. Cancer. 10: 278-92. PMID 20300104 DOI: 10.1038/Nrc2823  0.4
2010 Manning G, Hunter T. Eukaryotic kinomes. genomics and evolution of protein kinases Handbook of Cell Signaling, 2/E. 2: 393-397. DOI: 10.1016/B978-0-12-374145-5.00056-5  0.59
2009 You Z, Shi LZ, Zhu Q, Wu P, Zhang YW, Basilio A, Tonnu N, Verma IM, Berns MW, Hunter T. CtIP links DNA double-strand break sensing to resection. Molecular Cell. 36: 954-69. PMID 20064462 DOI: 10.1016/J.Molcel.2009.12.002  0.49
2009 Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G, Morgan DO, Tsai LH, Wolgemuth DJ. Cyclin-dependent kinases: a family portrait. Nature Cell Biology. 11: 1275-6. PMID 19884882 DOI: 10.1038/Ncb1109-1275  0.73
2009 Zhang YW, Brognard J, Coughlin C, You Z, Dolled-Filhart M, Aslanian A, Manning G, Abraham RT, Hunter T. The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Molecular Cell. 35: 442-53. PMID 19716789 DOI: 10.1016/J.Molcel.2009.06.030  0.633
2009 Carrano AC, Liu Z, Dillin A, Hunter T. A conserved ubiquitination pathway determines longevity in response to diet restriction. Nature. 460: 396-9. PMID 19553937 DOI: 10.1038/Nature08130  0.589
2009 Lu Z, Hunter T. Degradation of activated protein kinases by ubiquitination. Annual Review of Biochemistry. 78: 435-75. PMID 19489726 DOI: 10.1146/Annurev.Biochem.013008.092711  0.457
2009 Pearson GW, Hunter T. PI-3 kinase activity is necessary for ERK1/2-induced disruption of mammary epithelial architecture. Breast Cancer Research : Bcr. 11: R29. PMID 19457236 DOI: 10.1186/Bcr2259  0.691
2009 Hunter T. Tyrosine phosphorylation: thirty years and counting. Current Opinion in Cell Biology. 21: 140-6. PMID 19269802 DOI: 10.1016/J.Ceb.2009.01.028  0.4
2009 Copp J, Manning G, Hunter T. TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. Cancer Research. 69: 1821-7. PMID 19244117 DOI: 10.1158/0008-5472.Can-08-3014  0.63
2009 Smith JJ, Putta S, Zhu W, Pao GM, Verma IM, Hunter T, Bryant SV, Gardiner DM, Harkins TT, Voss SR. Genic regions of a large salamander genome contain long introns and novel genes. Bmc Genomics. 10: 19. PMID 19144141 DOI: 10.1186/1471-2164-10-19  0.738
2009 Monaghan JR, Epp LG, Putta S, Page RB, Walker JA, Beachy CK, Zhu W, Pao GM, Verma IM, Hunter T, Bryant SV, Gardiner DM, Harkins TT, Voss SR. Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration. Bmc Biology. 7: 1. PMID 19144100 DOI: 10.1186/1741-7007-7-1  0.741
2008 Bailis JM, Luche DD, Hunter T, Forsburg SL. Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote s-phase genome stability. Molecular and Cellular Biology. 28: 1724-38. PMID 18180284 DOI: 10.1128/Mcb.01717-07  0.399
2007 Pearson GW, Hunter T. Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells. The Journal of Cell Biology. 179: 1555-67. PMID 18166657 DOI: 10.1083/Jcb.200706099  0.742
2007 Hunter T. The age of crosstalk: phosphorylation, ubiquitination, and beyond. Molecular Cell. 28: 730-8. PMID 18082598 DOI: 10.1016/J.Molcel.2007.11.019  0.365
2007 You Z, Bailis JM, Johnson SA, Dilworth SM, Hunter T. Rapid activation of ATM on DNA flanking double-strand breaks. Nature Cell Biology. 9: 1311-8. PMID 17952060 DOI: 10.1038/Ncb1651  0.305
2007 Sun H, Leverson JD, Hunter T. Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins. The Embo Journal. 26: 4102-12. PMID 17762864 DOI: 10.1038/Sj.Emboj.7601839  0.391
2007 Zhang Y, Daum S, Wildemann D, Zhou XZ, Verdecia MA, Bowman ME, Lücke C, Hunter T, Lu KP, Fischer G, Noel JP. Structural basis for high-affinity peptide inhibition of human Pin1. Acs Chemical Biology. 2: 320-8. PMID 17518432 DOI: 10.1021/Cb7000044  0.462
2007 Johnson SA, You Z, Hunter T. Monitoring ATM kinase activity in living cells. Dna Repair. 6: 1277-84. PMID 17428747 DOI: 10.1016/J.Dnarep.2007.02.025  0.423
2007 Han EKH, Leverson JD, McGonigal T, Shah OJ, Woods KW, Hunter T, Giranda VL, Luo Y. Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition Oncogene. 26: 5655-5661. PMID 17334390 DOI: 10.1038/Sj.Onc.1210343  0.414
2007 Bozulic L, Morin P, Hunter T, Hemmings BA. Meeting report: targeting the kinome--20 years of tyrosine kinase inhibitor research in Basel. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe8. PMID 17317657 DOI: 10.1126/Stke.3742007Pe8  0.335
2007 Fang D, Hawke D, Zheng Y, Xia Y, Meisenhelder J, Nika H, Mills GB, Kobayashi R, Hunter T, Lu Z. Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity. The Journal of Biological Chemistry. 282: 11221-9. PMID 17287208 DOI: 10.1074/Jbc.M611871200  0.334
2007 Xia Y, Wang J, Liu TJ, Yung WK, Hunter T, Lu Z. c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis. Molecular Cell. 25: 219-32. PMID 17244530 DOI: 10.1016/J.Molcel.2007.01.005  0.312
2007 Xia Y, Wang J, Xu S, Johnson GL, Hunter T, Lu Z. MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress. Molecular and Cellular Biology. 27: 510-7. PMID 17101801 DOI: 10.1128/Mcb.01355-06  0.337
2007 Hunter T. Tyrosine phosphorylation: from discovery to the kinome and beyond The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A3-D  0.39
2006 Ghosh S, Tergaonkar V, Rothlin CV, Correa RG, Bottero V, Bist P, Verma IM, Hunter T. Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival. Cancer Cell. 10: 215-26. PMID 16959613 DOI: 10.1016/J.Ccr.2006.08.007  0.488
2006 Shah OJ, Hunter T. Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis. Molecular and Cellular Biology. 26: 6425-34. PMID 16914728 DOI: 10.1128/Mcb.01254-05  0.366
2006 Joazeiro CA, Anderson KC, Hunter T. Proteasome inhibitor drugs on the rise. Cancer Research. 66: 7840-2. PMID 16861477 DOI: 10.1158/0008-5472.Can-06-2033  0.679
2006 Wolff S, Ma H, Burch D, Maciel GA, Hunter T, Dillin A. SMK-1, an essential regulator of DAF-16-mediated longevity. Cell. 124: 1039-53. PMID 16530049 DOI: 10.1016/J.Cell.2005.12.042  0.586
2006 Petersen P, Chou DM, You Z, Hunter T, Walter JC, Walter G. Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint. Molecular and Cellular Biology. 26: 1997-2011. PMID 16479016 DOI: 10.1128/Mcb.26.5.1997-2011.2006  0.371
2006 Zhang YW, Hunter T, Abraham RT. Turning the replication checkpoint on and off. Cell Cycle (Georgetown, Tex.). 5: 125-8. PMID 16357541 DOI: 10.4161/Cc.5.2.2308  0.366
2005 Hunter T, Schulman H. CaMKII structure--an elegant design. Cell. 123: 765-7. PMID 16325572 DOI: 10.1016/J.Cell.2005.11.017  0.365
2005 Kamada S, Kikkawa U, Tsujimoto Y, Hunter T. A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association. Molecular and Cellular Biology. 25: 9469-77. PMID 16227597 DOI: 10.1128/Mcb.25.21.9469-9477.2005  0.347
2005 Watanabe N, Arai H, Iwasaki J, Shiina M, Ogata K, Hunter T, Osada H. Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways. Proceedings of the National Academy of Sciences of the United States of America. 102: 11663-8. PMID 16085715 DOI: 10.1073/Pnas.0500410102  0.394
2005 You Z, Chahwan C, Bailis J, Hunter T, Russell P. ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Molecular and Cellular Biology. 25: 5363-79. PMID 15964794 DOI: 10.1128/Mcb.25.13.5363-5379.2005  0.33
2005 Wang X, Li X, Meisenhelder J, Hunter T, Yoshida S, Asami T, Chory J. Autoregulation and homodimerization are involved in the activation of the plant steroid receptor BRI1. Developmental Cell. 8: 855-65. PMID 15935775 DOI: 10.1016/J.Devcel.2005.05.001  0.422
2005 Takagi Y, Masuda CA, Chang WH, Komori H, Wang D, Hunter T, Joazeiro CA, Kornberg RD. Ubiquitin ligase activity of TFIIH and the transcriptional response to DNA damage. Molecular Cell. 18: 237-43. PMID 15837426 DOI: 10.1016/J.Molcel.2005.03.007  0.704
2005 Johnson SA, Hunter T. Kinomics: methods for deciphering the kinome. Nature Methods. 2: 17-25. PMID 15789031 DOI: 10.1038/Nmeth731  0.464
2005 Woodring PJ, Hunter T, Wang JY. Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition. The Journal of Biological Chemistry. 280: 10318-25. PMID 15632178 DOI: 10.1074/Jbc.M410658200  0.404
2005 Hunter T. Protein-serine kinase receptors? Current Biology : Cb. 1: 15-6. PMID 15336194 DOI: 10.1016/0960-9822(91)90113-B  0.41
2004 York JD, Hunter T. Signal transduction. Unexpected mediators of protein phosphorylation. Science (New York, N.Y.). 306: 2053-5. PMID 15604398 DOI: 10.1126/Science.1107225  0.398
2004 Grabbe C, Zervas CG, Hunter T, Brown NH, Palmer RH. Focal adhesion kinase is not required for integrin function or viability in Drosophila. Development (Cambridge, England). 131: 5795-805. PMID 15525665 DOI: 10.1242/Dev.01462  0.418
2004 Shah OJ, Wang Z, Hunter T. Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Current Biology : Cb. 14: 1650-6. PMID 15380067 DOI: 10.1016/J.Cub.2004.08.026  0.324
2004 Caenepeel S, Charydczak G, Sudarsanam S, Hunter T, Manning G. The mouse kinome: discovery and comparative genomics of all mouse protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 101: 11707-12. PMID 15289607 DOI: 10.1073/Pnas.0306880101  0.649
2004 Alonso A, Sasin J, Bottini N, Friedberg I, Osterman A, Godzik A, Hunter T, Dixon J, Mustelin T. Protein tyrosine phosphatases in the human genome Cell. 117: 699-711. PMID 15186772 DOI: 10.1016/J.Cell.2004.05.018  0.388
2004 Woodring PJ, Meisenhelder J, Johnson SA, Zhou GL, Field J, Shah K, Bladt F, Pawson T, Niki M, Pandolfi PP, Wang JY, Hunter T. c-Abl phosphorylates Dok1 to promote filopodia during cell spreading. The Journal of Cell Biology. 165: 493-503. PMID 15148308 DOI: 10.1083/Jcb.200312171  0.397
2004 Watanabe N, Arai H, Nishihara Y, Taniguchi M, Watanabe N, Hunter T, Osada H. M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP. Proceedings of the National Academy of Sciences of the United States of America. 101: 4419-24. PMID 15070733 DOI: 10.1073/Pnas.0307700101  0.393
2004 Hunter T, Eckhart W. The discovery of tyrosine phosphorylation: it's all in the buffer! Cell. 116: S35-9, 1 p following. PMID 15055579 DOI: 10.1016/S0092-8674(04)00049-2  0.651
2004 Shah OJ, Hunter T. Critical role of T-loop and H-motif phosphorylation in the regulation of S6 kinase 1 by the tuberous sclerosis complex. The Journal of Biological Chemistry. 279: 20816-23. PMID 14993219 DOI: 10.1074/Jbc.M400957200  0.41
2004 Fukunaga R, Hunter T. Identification of MAPK substrates by expression screening with solid-phase phosphorylation. Methods in Molecular Biology (Clifton, N.J.). 250: 211-36. PMID 14755091 DOI: 10.1385/1-59259-671-1:211  0.702
2004 Pines J, Hunter T. Cyclin-dependent kinases: a new cell cycle motif? Trends in Cell Biology. 1: 117-21. PMID 14731542 DOI: 10.1016/0962-8924(91)90116-Q  0.458
2004 Lu Z, Hunter T. Wnt-Independent ?-catenin Transactivation in Tumor Developement Cell Cycle. 3: 569-571. DOI: 10.4161/Cc.3.5.885  0.3
2003 Lu Z, Ghosh S, Wang Z, Hunter T. Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion. Cancer Cell. 4: 499-515. PMID 14706341 DOI: 10.1016/S1535-6108(03)00304-0  0.339
2003 Liou YC, Sun A, Ryo A, Zhou XZ, Yu ZX, Huang HK, Uchida T, Bronson R, Bing G, Li X, Hunter T, Lu KP. Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration. Nature. 424: 556-61. PMID 12891359 DOI: 10.1038/Nature01832  0.498
2003 Lorén CE, Englund C, Grabbe C, Hallberg B, Hunter T, Palmer RH. A crucial role for the Anaplastic lymphoma kinase receptor tyrosine kinase in gut development in Drosophila melanogaster. Embo Reports. 4: 781-6. PMID 12855999 DOI: 10.1038/Sj.Embor.Embor897  0.396
2003 Sonnenburg ED, Bilwes A, Hunter T, Noel JP. The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region. Biochemistry. 42: 7904-14. PMID 12834342 DOI: 10.1021/Bi0340503  0.311
2003 Woodring PJ, Hunter T, Wang JY. Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases. Journal of Cell Science. 116: 2613-26. PMID 12775773 DOI: 10.1242/Jcs.00622  0.338
2003 O'Connell MJ, Krien MJ, Hunter T. Never say never. The NIMA-related protein kinases in mitotic control. Trends in Cell Biology. 13: 221-8. PMID 12742165 DOI: 10.1016/S0962-8924(03)00056-4  0.401
2003 Shah OJ, Ghosh S, Hunter T. Mitotic regulation of ribosomal S6 kinase 1 involves Ser/Thr, Pro phosphorylation of consensus and non-consensus sites by Cdc2. The Journal of Biological Chemistry. 278: 16433-42. PMID 12586835 DOI: 10.1074/Jbc.M300435200  0.453
2003 Uchida T, Takamiya M, Takahashi M, Miyashita H, Ikeda H, Terada T, Matsuo Y, Shirouzu M, Yokoyama S, Fujimori F, Hunter T. Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation. Chemistry & Biology. 10: 15-24. PMID 12573694 DOI: 10.1016/S1074-5521(02)00310-1  0.315
2003 Verdecia MA, Joazeiro CA, Wells NJ, Ferrer JL, Bowman ME, Hunter T, Noel JP. Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase. Molecular Cell. 11: 249-59. PMID 12535537 DOI: 10.1016/S1097-2765(02)00774-8  0.723
2003 Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. The protein kinase complement of the human genome. Science (New York, N.Y.). 298: 1912-34. PMID 12471243 DOI: 10.1126/Science.1075762  0.647
2003 Xia Y, Pao GM, Chen HW, Verma IM, Hunter T. Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein Journal of Biological Chemistry. 278: 5255-5263. PMID 12431996 DOI: 10.1074/Jbc.M204591200  0.769
2003 Hunter T, Manning G. Eukaryotic Kinomes: Genomic Cataloguing of Protein Kinases and Their Evolution Handbook of Cell Signaling. 1: 373-377. DOI: 10.1016/B978-012124546-7/50427-7  0.59
2002 Gilman AG, Simon MI, Bourne HR, Harris BA, Long R, Ross EM, Stull JT, Taussig R, Bourne HR, Arkin AP, Cobb MH, Cyster JG, Devreotes PN, Ferrell JE, Fruman D, ... ... Hunter T, et al. Overview of the Alliance for Cellular Signaling. Nature. 420: 703-6. PMID 12478301 DOI: 10.1038/Nature01304  0.471
2002 Manning G, Plowman GD, Hunter T, Sudarsanam S. Evolution of protein kinase signaling from yeast to man. Trends in Biochemical Sciences. 27: 514-20. PMID 12368087 DOI: 10.1016/S0968-0004(02)02179-5  0.663
2002 Carter N, Nakamoto T, Hirai H, Hunter T. EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas). Nature Cell Biology. 4: 565-73. PMID 12134157 DOI: 10.1038/Ncb823  0.321
2002 Hunter T. Tyrosine phosphorylation in cell signaling and disease. The Keio Journal of Medicine. 51: 61-71. PMID 12125907 DOI: 10.2302/Kjm.51.61  0.358
2002 Mollinari C, Kleman JP, Jiang W, Schoehn G, Hunter T, Margolis RL. PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone. The Journal of Cell Biology. 157: 1175-86. PMID 12082078 DOI: 10.1083/Jcb.200111052  0.393
2002 Lu Z, Xu S, Joazeiro C, Cobb MH, Hunter T. The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2. Molecular Cell. 9: 945-56. PMID 12049732 DOI: 10.1016/S1097-2765(02)00519-1  0.791
2002 Leverson JD, Huang HK, Forsburg SL, Hunter T. The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis. Molecular Biology of the Cell. 13: 1132-43. PMID 11950927 DOI: 10.1091/Mbc.01-07-0330  0.388
2002 Woodring PJ, Litwack ED, O'Leary DD, Lucero GR, Wang JY, Hunter T. Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension. The Journal of Cell Biology. 156: 879-92. PMID 11864995 DOI: 10.1083/Jcb.200110014  0.354
2002 Fang D, Elly C, Gao B, Fang N, Altman Y, Joazeiro C, Hunter T, Copeland N, Jenkins N, Liu YC. Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation. Nature Immunology. 3: 281-7. PMID 11828324 DOI: 10.1038/Ni763  0.692
2002 Liou YC, Ryo A, Huang HK, Lu PJ, Bronson R, Fujimori F, Uchida T, Hunter T, Lu KP. Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 99: 1335-40. PMID 11805292 DOI: 10.1073/Pnas.032404099  0.505
2002 Mustelin T, Hunter T. Meeting at mitosis: cell cycle-specific regulation of c-Src by RPTPalpha. Science's Stke : Signal Transduction Knowledge Environment. 2002: pe3. PMID 11796915 DOI: 10.1126/Stke.2002.115.Pe3  0.439
2001 Meisenhelder J, Hunter T, van der Geer P. Phosphopeptide mapping and identification of phosphorylation sites. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit13.9. PMID 18429120 DOI: 10.1002/0471140864.Ps1309S18  0.423
2001 Buck M, Poli V, Hunter T, Chojkier M. C/EBPbeta phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival. Molecular Cell. 8: 807-16. PMID 11684016 DOI: 10.1016/S1097-2765(01)00374-4  0.325
2001 Rankin CA, Joazeiro CAP, Floor E, Hunter T. E3 ubiquitin-protein ligase activity of parkin is dependent on cooperative interaction of RING finger (TRIAD) elements Journal of Biomedical Science. 8: 421-429. PMID 11549885 DOI: 10.1007/Bf02255952  0.34
2001 Lorén CE, Scully A, Grabbe C, Edeen PT, Thomas J, McKeown M, Hunter T, Palmer RH. Identification and characterization of DAlk: a novel Drosophila melanogaster RTK which drives ERK activation in vivo. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 6: 531-44. PMID 11442633 DOI: 10.1046/J.1365-2443.2001.00440.X  0.394
2001 Tertoolen LG, Blanchetot C, Jiang G, Overvoorde J, Gadella TW, Hunter T, den Hertog J. Dimerization of receptor protein-tyrosine phosphatase alpha in living cells. Bmc Cell Biology. 2: 8. PMID 11401727 DOI: 10.1186/1471-2121-2-8  0.625
2001 Lu Z, Jiang G, Blume-Jensen P, Hunter T. Epidermal Growth Factor-Induced Tumor Cell Invasion and Metastasis Initiated by Dephosphorylation and Downregulation of Focal Adhesion Kinase Molecular and Cellular Biology. 21: 4016-4031. PMID 11359909 DOI: 10.1128/Mcb.21.12.4016-4031.2001  0.383
2001 Blume-Jensen P, Hunter T. Oncogenic kinase signalling. Nature. 411: 355-365. PMID 11357143 DOI: 10.1038/35077225  0.43
2001 Ruffner H, Joazeiro CAP, Hemmati D, Hunter T, Verma IM. Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity Proceedings of the National Academy of Sciences of the United States of America. 98: 5134-5139. PMID 11320250 DOI: 10.1073/Pnas.081068398  0.486
2001 Woodring PJ, Hunter T, Wang JY. Inhibition of c-Abl tyrosine kinase activity by filamentous actin. The Journal of Biological Chemistry. 276: 27104-10. PMID 11309382 DOI: 10.1074/Jbc.M100559200  0.358
2001 Hauck CR, Hunter T, Schlaepfer DD. The v-Src SH3 domain facilitates a cell adhesion-independent association with focal adhesion kinase. The Journal of Biological Chemistry. 276: 17653-62. PMID 11278488 DOI: 10.1074/Jbc.M009329200  0.403
2001 Moniakis J, Funamoto S, Fukuzawa M, Meisenhelder J, Araki T, Abe T, Meili R, Hunter T, Williams J, Firtel RA. An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway. Genes & Development. 15: 687-98. PMID 11274054 DOI: 10.1101/Gad.871001  0.392
2001 Early A, Gamper M, Moniakis J, Kim E, Hunter T, Williams JG, Firtel RA. Protein tyrosine phosphatase PTP1 negatively regulates Dictyostelium STATa and is required for proper cell-type proportioning. Developmental Biology. 232: 233-45. PMID 11254360 DOI: 10.1006/Dbio.2001.0171  0.44
2001 Potter LR, Hunter T. Guanylyl cyclase-linked natriuretic peptide receptors: structure and regulation. The Journal of Biological Chemistry. 276: 6057-60. PMID 11152699 DOI: 10.1074/Jbc.R000033200  0.598
2000 Joazeiro CA, Hunter T. Biochemistry. Ubiquitination--more than two to tango. Science (New York, N.Y.). 289: 2061-2. PMID 11032556 DOI: 10.1126/Science.289.5487.2061  0.306
2000 Hefner Y, Borsch-Haubold AG, Murakami M, Wilde JI, Pasquet S, Schieltz D, Ghomashchi F, Yates JR, Armstrong CG, Paterson A, Cohen P, Fukunaga R, Hunter T, Kudo I, Watson SP, et al. Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases. The Journal of Biological Chemistry. 275: 37542-51. PMID 10978317 DOI: 10.1074/Jbc.M003395200  0.445
2000 Qiu L, Joazeiro C, Fang N, Wang HY, Elly C, Altman Y, Fang D, Hunter T, Liu YC. Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase. The Journal of Biological Chemistry. 275: 35734-7. PMID 10940313 DOI: 10.1074/Jbc.M007300200  0.34
2000 Friedrichsen DM, Joazeiro CA, Li J, Hunter T, Chory J. Brassinosteroid-insensitive-1 is a ubiquitously expressed leucine-rich repeat receptor serine/threonine kinase. Plant Physiology. 123: 1247-56. PMID 10938344 DOI: 10.1104/Pp.123.4.1247  0.418
2000 Verdecia MA, Bowman ME, Lu KP, Hunter T, Noel JP. Structural basis for phosphoserine-proline recognition by group IV WW domains. Nature Structural Biology. 7: 639-43. PMID 10932246 DOI: 10.1038/77929  0.496
2000 Potter LR, Hunter T. Activation of protein kinase C stimulates the dephosphorylation of natriuretic peptide receptor-B at a single serine residue: a possible mechanism of heterologous desensitization. The Journal of Biological Chemistry. 275: 31099-106. PMID 10915802 DOI: 10.1074/Jbc.M005506200  0.662
2000 Jiang G, den Hertog J, Hunter T. Receptor-like protein tyrosine phosphatase alpha homodimerizes on the cell surface. Molecular and Cellular Biology. 20: 5917-29. PMID 10913175 DOI: 10.1128/Mcb.20.16.5917-5929.2000  0.612
2000 Leverson JD, Joazeiro CA, Page AM, Huang Hk, Hieter P, Hunter T. The APC11 RING-H2 finger mediates E2-dependent ubiquitination. Molecular Biology of the Cell. 11: 2315-25. PMID 10888670 DOI: 10.1091/Mbc.11.7.2315  0.313
2000 Verdecia MA, Huang H, Dutil E, Kaiser DA, Hunter T, Noel JP. Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement. Nature Structural Biology. 7: 602-8. PMID 10876248 DOI: 10.1038/76838  0.327
2000 Xu S, Huang HK, Kaiser P, Latterich M, Hunter T. Phosphorylation and spindle pole body localization of the Cdc15p mitotic regulatory protein kinase in budding yeast. Current Biology : Cb. 10: 329-32. PMID 10744974 DOI: 10.1016/S0960-9822(00)00382-1  0.446
2000 Cassman M, Hunter T, Pawson T. Proteins suggest form of their own database. Nature. 403: 591-2. PMID 10688172 DOI: 10.1038/35001230  0.32
2000 Pao GM, Janknecht R, Ruffner H, Hunter T, Verma IM. CBP/p300 interact with and function as transcriptional coactivators of BRCA1 Proceedings of the National Academy of Sciences of the United States of America. 97: 1020-1025. PMID 10655477 DOI: 10.1073/Pnas.97.3.1020  0.766
2000 Blume-Jensen P, Jiang G, Hyman R, Lee KF, O'Gorman S, Hunter T. Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility. Nature Genetics. 24: 157-62. PMID 10655061 DOI: 10.1038/72814  0.388
2000 Potter LR, Hunter T. Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B. Methods (San Diego, Calif.). 19: 506-20. PMID 10581150 DOI: 10.1006/Meth.1999.0893  0.657
1999 Pearson KL, Hunter T, Janknecht R. Activation of Smad1-mediated transcription by p300/CBP. Biochimica Et Biophysica Acta. 1489: 354-64. PMID 10673036 DOI: 10.1016/S0167-4781(99)00166-9  0.384
1999 Palmer RH, Fessler LI, Edeen PT, Madigan SJ, McKeown M, Hunter T. DFak56 is a novel Drosophila melanogaster focal adhesion kinase. The Journal of Biological Chemistry. 274: 35621-9. PMID 10585440 DOI: 10.1074/Jbc.274.50.35621  0.446
1999 Plowman GD, Sudarsanam S, Bingham J, Whyte D, Hunter T. The protein kinases of Caenorhabditis elegans: A model for signal transduction in multicellular organisms Proceedings of the National Academy of Sciences of the United States of America. 96: 13603-13610. PMID 10570119 DOI: 10.1073/Pnas.96.24.13603  0.439
1999 Jiang G, den Hertog J, Su J, Noel J, Sap J, Hunter T. Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alpha. Nature. 401: 606-10. PMID 10524630 DOI: 10.1038/44170  0.646
1999 Jiang W, McDonald D, Hope TJ, Hunter T. Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication. The Embo Journal. 18: 5703-13. PMID 10523313 DOI: 10.1093/Emboj/18.20.5703  0.465
1999 Joazeiro CA, Wing SS, Huang H, Leverson JD, Hunter T, Liu YC. The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase. Science (New York, N.Y.). 286: 309-12. PMID 10514377 DOI: 10.1126/Science.286.5438.309  0.431
1999 Zheng C, Xiang J, Hunter T, Lin A. The JNKK2-JNK1 fusion protein acts as a constitutively active c-Jun kinase that stimulates c-Jun transcription activity. The Journal of Biological Chemistry. 274: 28966-71. PMID 10506143 DOI: 10.1074/Jbc.274.41.28966  0.467
1999 Jiang G, Hunter T. Receptor signaling: when dimerization is not enough. Current Biology : Cb. 9: R568-71. PMID 10469554 DOI: 10.1016/S0960-9822(99)80357-1  0.334
1999 Biggs WH, Meisenhelder J, Hunter T, Cavenee WK, Arden KC. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proceedings of the National Academy of Sciences of the United States of America. 96: 7421-6. PMID 10377430 DOI: 10.1073/Pnas.96.13.7421  0.438
1999 Ruffner H, Jiang W, Craig AG, Hunter T, Verma IM. BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site. Molecular and Cellular Biology. 19: 4843-54. PMID 10373534 DOI: 10.1128/Mcb.19.7.4843  0.59
1999 Potter LR, Hunter T. A constitutively "phosphorylated" guanylyl cyclase-linked atrial natriuretic peptide receptor mutant is resistant to desensitization. Molecular Biology of the Cell. 10: 1811-20. PMID 10359598 DOI: 10.1091/Mbc.10.6.1811  0.672
1999 Jiang W, Wells NJ, Hunter T. Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6. Proceedings of the National Academy of Sciences of the United States of America. 96: 6193-8. PMID 10339564 DOI: 10.1073/Pnas.96.11.6193  0.404
1999 Gamper M, Kim E, Howard PK, Ma H, Hunter T, Firtel RA. Regulation of Dictyostelium protein-tyrosine phosphatase-3 (PTP3) through osmotic shock and stress stimulation and identification of pp130 as a PTP3 substrate. The Journal of Biological Chemistry. 274: 12129-38. PMID 10207040 DOI: 10.1074/Jbc.274.17.12129  0.447
1999 Sekiguchi T, Nishimoto T, Hunter T. Overexpression of D-type cyclins, E2F-1, SV40 large T antigen and HPV16 E7 rescue cell cycle arrest of tsBN462 cells caused by the CCG1/TAF(II)250 mutation. Oncogene. 18: 1797-806. PMID 10086334 DOI: 10.1038/Sj.Onc.1202508  0.321
1999 Pyronnet S, Imataka H, Gingras AC, Fukunaga R, Hunter T, Sonenberg N. Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E. The Embo Journal. 18: 270-9. PMID 9878069 DOI: 10.1093/Emboj/18.1.270  0.451
1998 Jiang W, Jimenez G, Wells NJ, Hope TJ, Wahl GM, Hunter T, Fukunaga R. PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis. Molecular Cell. 2: 877-85. PMID 9885575 DOI: 10.1016/S1097-2765(00)80302-0  0.425
1998 Sieg DJ, Ilić D, Jones KC, Damsky CH, Hunter T, Schlaepfer DD. Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration. The Embo Journal. 17: 5933-47. PMID 9774338 DOI: 10.1093/Emboj/17.20.5933  0.434
1998 Schlaepfer DD, Hunter T. Integrin signalling and tyrosine phosphorylation: just the FAKs? Trends in Cell Biology. 8: 151-7. PMID 9695829 DOI: 10.1016/S0962-8924(97)01172-0  0.422
1998 Blume-Jensen P, Janknecht R, Hunter T. The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136. Current Biology : Cb. 8: 779-82. PMID 9651683 DOI: 10.1016/S0960-9822(98)70302-1  0.448
1998 Orend G, Hunter T, Ruoslahti E. Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21(Cip1) and p27(Kip1) in anchorage-independent cells Oncogene. 16: 2575-2583. PMID 9632134 DOI: 10.1038/Sj.Onc.1201791  0.369
1998 Potter LR, Hunter T. Identification and characterization of the major phosphorylation sites of the B-type natriuretic peptide receptor. The Journal of Biological Chemistry. 273: 15533-9. PMID 9624142 DOI: 10.1074/Jbc.273.25.15533  0.68
1998 Hunter T. The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 353: 583-605. PMID 9602534 DOI: 10.1098/Rstb.1998.0228  0.471
1998 Schlaepfer DD, Jones KC, Hunter T. Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events. Molecular and Cellular Biology. 18: 2571-85. PMID 9566877 DOI: 10.1128/Mcb.18.5.2571  0.432
1998 Lu KP, Hunter T. The NIMA kinase: a mitotic regulator in Aspergillus nidulans and vertebrate cells. Progress in Cell Cycle Research. 1: 187-205. PMID 9552363 DOI: 10.1007/978-1-4615-1809-9_15  0.563
1998 Potter LR, Hunter T. Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor. Molecular and Cellular Biology. 18: 2164-72. PMID 9528788 DOI: 10.1128/Mcb.18.4.2164  0.68
1998 Sekiguchi T, Hunter T. Induction of growth arrest and cell death by overexpression of the cyclin-Cdk inhibitor p21 in hamster BHK21 cells Oncogene. 16: 369-380. PMID 9467962 DOI: 10.1038/Sj.Onc.1201539  0.358
1998 Hunter T. Prolyl isomerases and nuclear function. Cell. 92: 141-3. PMID 9458036 DOI: 10.1016/S0092-8674(00)80906-X  0.394
1998 Majeti R, Bilwes AM, Noel JP, Hunter T, Weiss A. Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge. Science (New York, N.Y.). 279: 88-91. PMID 9417031 DOI: 10.1126/Science.279.5347.88  0.35
1998 Jiang W, Hunter T. Identification and characterization of a human protein kinase related to budding yeast Cdc7p. Proceedings of the National Academy of Sciences of the United States of America. 94: 14320-5. PMID 9405610 DOI: 10.1073/Pnas.94.26.14320  0.464
1998 Shen M, Haggblom C, Vogt M, Hunter T, Lu KP. Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis. Proceedings of the National Academy of Sciences of the United States of America. 94: 13618-23. PMID 9391075 DOI: 10.1073/Pnas.94.25.13618  0.545
1998 Herdegen T, Claret F, Kallunki T, Martin-Villalba A, Winter C, Hunter T, Karin M. Lasting N-Terminal Phosphorylation of c-Jun and Activation of c-Jun N-Terminal Kinases after Neuronal Injury The Journal of Neuroscience. 18: 5124-5135. DOI: 10.1523/Jneurosci.18-14-05124.1998  0.371
1997 Li S, Kim M, Hu YL, Jalali S, Schlaepfer DD, Hunter T, Chien S, Shyy JY. Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases. The Journal of Biological Chemistry. 272: 30455-62. PMID 9374537 DOI: 10.1074/Jbc.272.48.30455  0.405
1997 Sakamoto Y, Yoshida M, Semba K, Hunter T. Inhibition of the DNA-binding and transcriptional repression activity of the Wilms' tumor gene product, WT1, by cAMP-dependent protein kinase-mediated phosphorylation of Ser-365 and Ser-393 in the zinc finger domain. Oncogene. 15: 2001-12. PMID 9366517 DOI: 10.1038/Sj.Onc.1201391  0.437
1997 Stein B, Yang MX, Young DB, Janknecht R, Hunter T, Murray BW, Barbosa MS. p38-2, a novel mitogen-activated protein kinase with distinct properties. The Journal of Biological Chemistry. 272: 19509-17. PMID 9235954 DOI: 10.1074/Jbc.272.31.19509  0.385
1997 Ranganathan R, Lu KP, Hunter T, Noel JP. Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent. Cell. 89: 875-86. PMID 9200606 DOI: 10.1016/S0092-8674(00)80273-1  0.513
1997 Fukunaga R, Hunter T. MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates. The Embo Journal. 16: 1921-33. PMID 9155018 DOI: 10.1093/Emboj/16.8.1921  0.436
1997 Schlaepfer DD, Hunter T. Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src. The Journal of Biological Chemistry. 272: 13189-95. PMID 9148935 DOI: 10.1074/Jbc.272.20.13189  0.429
1997 Neet K, Hunter T. Vertebrate non-receptor protein-tyrosine kinase families. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 1: 147-69. PMID 9140060 DOI: 10.1046/J.1365-2443.1996.D01-234.X  0.32
1997 Janknecht R, Hunter T. Convergence of MAP kinase pathways on the ternary complex factor Sap-1a. The Embo Journal. 16: 1620-7. PMID 9130707 DOI: 10.1093/Emboj/16.7.1620  0.379
1997 Schlaepfer DD, Hunter T. Signal transduction from the extracellular matrix--a role for the focal adhesion protein-tyrosine kinase FAK. Cell Structure and Function. 21: 445-50. PMID 9118254 DOI: 10.1247/Csf.21.445  0.384
1997 Poon RYC, Lew J, Hunter T. Identification of functional domains in the neuronal Cdk5 activator protein Journal of Biological Chemistry. 272: 5703-5708. PMID 9038181 DOI: 10.1074/Jbc.272.9.5703  0.3
1997 Schlaepfer DD, Broome MA, Hunter T. Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins. Molecular and Cellular Biology. 17: 1702-13. PMID 9032297 DOI: 10.1128/Mcb.17.3.1702  0.454
1997 Hunter T, Plowman GD. The protein kinases of budding yeast: six score and more. Trends in Biochemical Sciences. 22: 18-22. PMID 9020587 DOI: 10.1016/S0968-0004(96)10068-2  0.407
1997 Janknecht R, Hunter T. Activation of the Sap-1a transcription factor by the c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase. The Journal of Biological Chemistry. 272: 4219-24. PMID 9020136 DOI: 10.1074/Jbc.272.7.4219  0.371
1997 Broome MA, Hunter T. The PDGF receptor phosphorylates Tyr 138 in the c-Src SH3 domain in vivo reducing peptide ligand binding. Oncogene. 14: 17-34. PMID 9010229 DOI: 10.1038/Sj.Onc.1200798  0.421
1997 Poon RY, Toyoshima H, Hunter T. On the masking of signals on immunoblots by cellular proteins. Journal of Immunological Methods. 199: 155-8. PMID 8982357 DOI: 10.1016/S0022-1759(96)00177-9  0.34
1996 Sekiguchi T, Noguchi E, Hayashida T, Nakashima T, Toyoshima H, Nishimoto T, Hunter T. D-type cyclin expression is decreased and p21 and p27 CDK inhibitor expression is increased when tsBN462 CCG1/TAF11250 mutant cells arrest in G1 at the restrictive temperature Genes to Cells. 1: 687-705. PMID 9078394 DOI: 10.1046/J.1365-2443.1996.00259.X  0.393
1996 Ofir R, Weinstein Y, Bazarsky E, Blagerman S, Wolfson M, Hunter T, Rager-Zisman B. Tyrosine phosphorylation of measles virus P-phosphoprotein in persistently infected neuroblastoma cells. Virus Genes. 13: 203-10. PMID 9035364 DOI: 10.1007/Bf00366980  0.44
1996 Songyang Z, Lu KP, Kwon YT, Tsai LH, Filhol O, Cochet C, Brickey DA, Soderling TR, Bartleson C, Graves DJ, DeMaggio AJ, Hoekstra MF, Blenis J, Hunter T, Cantley LC. A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1. Molecular and Cellular Biology. 16: 6486-93. PMID 8887677 DOI: 10.1128/Mcb.16.11.6486  0.573
1996 Schlaepfer DD, Hunter T. Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases. Molecular and Cellular Biology. 16: 5623-33. PMID 8816475 DOI: 10.1128/Mcb.16.10.5623  0.436
1996 Janknecht R, Hunter T. Versatile molecular glue. Transcriptional control. Current Biology : Cb. 6: 951-4. PMID 8805328 DOI: 10.1016/S0960-9822(02)00636-X  0.407
1996 Winston LA, Hunter T. Intracellular signalling: putting JAKs on the kinase MAP. Current Biology : Cb. 6: 668-71. PMID 8793290 DOI: 10.1016/S0960-9822(09)00445-X  0.389
1996 Hunter T. Tyrosine phosphorylation: past, present and future. Biochemical Society Transactions. 24: 307-27. PMID 8736758 DOI: 10.1042/Bst0240307  0.378
1996 Ezhevsky SA, Toyoshima H, Hunter T, Scott DW. Role of cyclin A and p27 in anti-IgM induced G1 growth arrest of murine B-cell lymphomas. Molecular Biology of the Cell. 7: 553-64. PMID 8730099 DOI: 10.1091/Mbc.7.4.553  0.404
1996 Bilwes AM, den Hertog J, Hunter T, Noel JP. Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization. Nature. 382: 555-9. PMID 8700232 DOI: 10.1038/382555A0  0.629
1996 den Hertog J, Hunter T. Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains. The Embo Journal. 15: 3016-27. PMID 8670803 DOI: 10.1002/J.1460-2075.1996.Tb00665.X  0.605
1996 Broome MA, Hunter T. Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling. The Journal of Biological Chemistry. 271: 16798-806. PMID 8663329 DOI: 10.1074/Jbc.271.28.16798  0.394
1996 Poon RY, Jiang W, Toyoshima H, Hunter T. Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage. The Journal of Biological Chemistry. 271: 13283-91. PMID 8662825 DOI: 10.1074/Jbc.271.22.13283  0.378
1996 Mal A, Poon RY, Howe PH, Toyoshima H, Hunter T, Harter ML. Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFbeta-treated cells. Nature. 380: 262-5. PMID 8637577 DOI: 10.1038/380262A0  0.382
1996 Fey MF, Moffat GJ, Vik DP, Meisenhelder J, Saris CJM, Hunter T, Tack BF. Complete structure of the murine p36 (annexin II) gene. Identification of mRNAs for both the murine and the human gene with alternatively spliced 5′ noncoding exons Biochimica Et Biophysica Acta. 1306: 160-170. PMID 8634333 DOI: 10.1016/0167-4781(95)00238-3  0.302
1996 Gamper M, Howard PK, Hunter T, Firtel RA. Multiple roles of the novel protein tyrosine phosphatase PTP3 during Dictyostelium growth and development. Molecular and Cellular Biology. 16: 2431-44. PMID 8628311 DOI: 10.1128/Mcb.16.5.2431  0.411
1996 Lu KP, Hanes SD, Hunter T. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature. 380: 544-7. PMID 8606777 DOI: 10.1038/380544A0  0.563
1996 Poon RY, Hunter T. Cell regulation. Innocent bystanders or chosen collaborators? Current Biology : Cb. 5: 1243-7. PMID 8574579 DOI: 10.1016/S0960-9822(95)00248-X  0.375
1996 Fang F, Orend G, Watanabe N, Hunter T, Ruoslahti E. Dependence of cyclin E-CDK2 kinase activity on cell anchorage. Science (New York, N.Y.). 271: 499-502. PMID 8560263 DOI: 10.1126/Science.271.5248.499  0.389
1996 Poon RY, Toyoshima H, Hunter T. Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation. Molecular Biology of the Cell. 6: 1197-213. PMID 8534916 DOI: 10.1091/Mbc.6.9.1197  0.328
1996 Bilwes AM, den Hertog J, Hunter T, Noel JP. Structural analysis of a dimeric state of the first intracellular domain of PTPa, a protein receptor-like tyrosine phosphatase Acta Crystallographica Section a Foundations of Crystallography. 52: C185-C185. DOI: 10.1107/S010876739609191X  0.339
1995 Winston LA, Hunter T. JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone. The Journal of Biological Chemistry. 270: 30837-40. PMID 8537333 DOI: 10.1074/Jbc.270.52.30837  0.428
1995 Haley A, Hunter T, Kiberstis P, Zimmern D. Multiple serine phosphorylation sites on the 30 kDa TMV cell‐to‐cell movement protein synthesized in tobacco protoplasts Plant Journal. 8: 715-724. PMID 8528282 DOI: 10.1046/J.1365-313X.1995.08050715.X  0.403
1995 Hunter T. Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell. 80: 225-36. PMID 7834742 DOI: 10.1016/0092-8674(95)90405-0  0.432
1995 Hoekstra MF, Dhillon N, Carmel G, DeMaggio AJ, Lindberg RA, Hunter T, Kuret J. Budding and fission yeast casein kinase I isoforms have dual-specificity protein kinase activity. Molecular Biology of the Cell. 5: 877-86. PMID 7803855 DOI: 10.1091/Mbc.5.8.877  0.469
1995 Sekiguchi T, Nakashima T, Hayashida T, Kuraoka A, Hashimoto S, Tsuchida N, Shibata Y, Hunter T, Nishimoto T. Apoptosis is induced in BHK cells by the tsBN462/13 mutation in the CCG1/TAFII250 subunit of the TFIID basal transcription factor. Experimental Cell Research. 218: 490-8. PMID 7796884 DOI: 10.1006/Excr.1995.1183  0.329
1995 Lu KP, Hunter T. Evidence for a NIMA-like mitotic pathway in vertebrate cells. Cell. 81: 413-24. PMID 7736593 DOI: 10.1016/0092-8674(95)90394-1  0.562
1995 Hunter T. 1001 protein kinases redux--towards 2000. Seminars in Cell Biology. 5: 367-76. PMID 7711285 DOI: 10.1006/Scel.1994.1044  0.467
1995 Karin M, Hunter T. Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus. Current Biology : Cb. 5: 747-57. PMID 7583121 DOI: 10.1016/S0960-9822(95)00151-5  0.425
1995 Poon RY, Hunter T. Dephosphorylation of Cdk2 Thr160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin. Science (New York, N.Y.). 270: 90-3. PMID 7569954 DOI: 10.1126/Science.270.5233.90  0.413
1995 Taylor SS, Radzio-Andzelm E, Hunter T. How do protein kinases discriminate between serine/threonine and tyrosine? Structural insights from the insulin receptor protein-tyrosine kinase Faseb Journal. 9: 1255-1266. PMID 7557015 DOI: 10.1096/Fasebj.9.13.7557015  0.449
1995 Hunter T. When is a lipid kinase not a lipid kinase? When it is a protein kinase. Cell. 83: 1-4. PMID 7553860 DOI: 10.1016/0092-8674(95)90225-2  0.381
1995 Neet K, Hunter T. The nonreceptor protein-tyrosine kinase CSK complexes directly with the GTPase-activating protein-associated p62 protein in cells expressing v-Src or activated c-Src. Molecular and Cellular Biology. 15: 4908-20. PMID 7544435 DOI: 10.1128/Mcb.15.9.4908  0.447
1995 Tracy S, van der Geer P, Hunter T. The receptor-like protein-tyrosine phosphatase, RPTP alpha, is phosphorylated by protein kinase C on two serines close to the inner face of the plasma membrane. The Journal of Biological Chemistry. 270: 10587-94. PMID 7537734 DOI: 10.1074/Jbc.270.18.10587  0.367
1995 Hanks SK, Hunter T. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1 The Faseb Journal. 9: 576-596. DOI: 10.1096/Fasebj.9.8.7768349  0.433
1995 Watanabe N, Broome M, Hunter T. Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle. The Embo Journal. 14: 1878-1891. DOI: 10.1002/J.1460-2075.1995.Tb07180.X  0.44
1994 Trautwein C, van der Geer P, Karin M, Hunter T, Chojkier M. Protein kinase A and C site-specific phosphorylations of LAP (NF-IL6) modulate its binding affinity to DNA recognition elements. The Journal of Clinical Investigation. 93: 2554-61. PMID 8200992 DOI: 10.1172/Jci117266  0.419
1994 van der Geer P, Hunter T. Phosphopeptide mapping and phosphoamino acid analysis by electrophoresis and chromatography on thin-layer cellulose plates. Electrophoresis. 15: 544-54. PMID 8055882 DOI: 10.1002/Elps.1150150173  0.34
1994 Kornbluth S, Sebastian B, Hunter T, Newport J. Membrane localization of the kinase which phosphorylates p34cdc2 on threonine 14. Molecular Biology of the Cell. 5: 273-82. PMID 8049520 DOI: 10.1091/Mbc.5.3.273  0.429
1994 Toyoshima H, Hunter T. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell. 78: 67-74. PMID 8033213 DOI: 10.1016/0092-8674(94)90573-8  0.371
1994 Zhang SH, Broome MA, Lawton MA, Hunter T, Lamb CJ. atpk1, a novel ribosomal protein kinase gene from Arabidopsis. II. Functional and biochemical analysis of the encoded protein. The Journal of Biological Chemistry. 269: 17593-9. PMID 8021267  0.339
1994 Schlaepfer DD, Hanks SK, Hunter T, van der Geer P. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature. 372: 786-91. PMID 7997267 DOI: 10.1038/372786A0  0.444
1994 van der Geer P, Hunter T, Lindberg RA. Receptor protein-tyrosine kinases and their signal transduction pathways. Annual Review of Cell Biology. 10: 251-337. PMID 7888178 DOI: 10.1146/Annurev.Cb.10.110194.001343  0.393
1994 den Hertog J, Tracy S, Hunter T. Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo. The Embo Journal. 13: 3020-32. PMID 7518772 DOI: 10.1002/J.1460-2075.1994.Tb06601.X  0.591
1994 Howard PK, Gamper M, Hunter T, Firtel RA. Regulation by protein-tyrosine phosphatase PTP2 is distinct from that by PTP1 during Dictyostelium growth and development Molecular and Cellular Biology. 14: 5154-5164. PMID 7518559 DOI: 10.1128/Mcb.14.8.5154  0.368
1994 Rigaudy P, Simon S, Hunter T, Sollazzo M, Billetta R, Zanetti M, Eckhart W. Antibodies specific for the neuronal form of the Src protein elicited by an antigenized antibody. Dna and Cell Biology. 13: 585-91. PMID 7517679 DOI: 10.1089/Dna.1994.13.585  0.619
1994 Pines J, Hunter T. The differential localization of human cyclins A and B is due to a cytoplasmic retention signal in cyclin B. The Embo Journal. 13: 3772-3781. DOI: 10.1002/J.1460-2075.1994.Tb06688.X  0.329
1993 Sebastian B, Kakizuka A, Hunter T. Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15. Proceedings of the National Academy of Sciences of the United States of America. 90: 3521-4. PMID 8475101 DOI: 10.1073/Pnas.90.8.3521  0.414
1993 Merlio JP, Ernfors P, Kokaia Z, Middlemas DS, Bengzon J, Kokaia M, Smith ML, Siesjö BK, Hunter T, Lindvall O. Increased production of the TrkB protein tyrosine kinase receptor after brain insults. Neuron. 10: 151-64. PMID 8439408 DOI: 10.1016/0896-6273(93)90307-D  0.319
1993 van der Geer P, Hunter T. Mutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts. The Embo Journal. 12: 5161-5172. DOI: 10.1002/J.1460-2075.1993.Tb06211.X  0.408
1992 Hunter T, Karin M. The regulation of transcription by phosphorylation. Cell. 70: 375-87. PMID 1643656 DOI: 10.1016/0092-8674(92)90162-6  0.362
1992 Freed E, Hunter T. A 41-kilodalton protein is a potential substrate for the p210bcr-abl protein-tyrosine kinase in chronic myelogenous leukemia cells. Molecular and Cellular Biology. 12: 1312-23. PMID 1545812 DOI: 10.1128/Mcb.12.3.1312  0.433
1992 Lock LF, Pines J, Hunter T, Gilbert DJ, Gopalan G, Jenkins NA, Copeland NG, Donovan PJ. A single cyclin A gene and multiple cyclin B1-related sequences are dispersed in the mouse genome. Genomics. 13: 415-24. PMID 1535334 DOI: 10.1016/0888-7543(92)90262-Q  0.338
1992 Lin A, Frost J, Deng T, Smeal T, al-Alawi N, Kikkawa U, Hunter T, Brenner D, Karin M. Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity. Cell. 70: 777-89. PMID 1516134 DOI: 10.1016/0092-8674(92)90311-Y  0.415
1992 DeMaggio AJ, Lindberg RA, Hunter T, Hoekstra MF. The budding yeast HRR25 gene product is a casein kinase I isoform Proceedings of the National Academy of Sciences of the United States of America. 89: 7008-7012. PMID 1495994 DOI: 10.1073/Pnas.89.15.7008  0.435
1992 Meisenhelder J, Hunter T. The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment. Molecular and Cellular Biology. 12: 5843-56. PMID 1448108 DOI: 10.1128/Mcb.12.12.5843  0.435
1992 Kikkawa U, Mann SKO, Firtel RA, Hunter T. Molecular cloning of casein kinase II α subunit from Dictyostelium discoideum and its expression in the life cycle Molecular and Cellular Biology. 12: 5711-5723. PMID 1448100 DOI: 10.1128/Mcb.12.12.5711  0.375
1992 Lindberg RA, Quinn AM, Hunter T. Dual-specificity protein kinases: will any hydroxyl do? Trends in Biochemical Sciences. 17: 114-9. PMID 1412695 DOI: 10.1016/0968-0004(92)90248-8  0.444
1992 Hunter T, Lindberg RA, Middlemas DS, Tracy S, van der Geer P. Receptor protein tyrosine kinases and phosphatases. Cold Spring Harbor Symposia On Quantitative Biology. 57: 25-41. PMID 1339664 DOI: 10.1101/Sqb.1992.057.01.005  0.354
1992 Kakizuka A, Sebastian B, Borgmeyer U, Hermans-Borgmeyer I, Bolado J, Hunter T, Hoekstra MF, Evans RM. A mouse cdc25 homolog is differentially and developmentally expressed. Genes & Development. 6: 578-90. PMID 1313771 DOI: 10.1101/Gad.6.4.578  0.424
1992 Devoto SH, Mudryj M, Pines J, Hunter T, Nevins JR. A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex. Cell. 68: 167-76. PMID 1310073 DOI: 10.1016/0092-8674(92)90215-X  0.444
1992 Reedijk M, Liu X, van der Geer P, Letwin K, Waterfield M, Hunter T, Pawson T. Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3′-kinase SH2 domains: a model for SH2-mediated receptor-target interactions. The Embo Journal. 11: 1365-1372. DOI: 10.1002/J.1460-2075.1992.Tb05181.X  0.409
1991 Lindberg RA, Hunter T. cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases. Molecular and Cellular Biology. 10: 6316-24. PMID 2174105 DOI: 10.1128/Mcb.10.12.6316  0.471
1991 Meisenhelder J, Hunter T. Phosphorylation of phospholipase C in vivo and in vitro. Methods in Enzymology. 197: 288-305. PMID 2051922 DOI: 10.1016/0076-6879(91)97154-Q  0.424
1991 Inoue J, Kerr LD, Ransone LJ, Bengal E, Hunter T, Verma IM. c-rel activates but v-rel suppresses transcription from kappa B sites. Proceedings of the National Academy of Sciences of the United States of America. 88: 3715-9. PMID 2023921 DOI: 10.1073/Pnas.88.9.3715  0.491
1991 Boyle WJ, Smeal T, Defize LHK, Angel P, Woodgett JR, Karin M, Hunter T. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity Cell. 64: 573-584. PMID 1846781 DOI: 10.1016/0092-8674(91)90241-P  0.422
1991 Middlemas DS, Lindberg RA, Hunter T. trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors. Molecular and Cellular Biology. 11: 143-53. PMID 1846020 DOI: 10.1128/Mcb.11.1.143  0.358
1991 Nevins JR, Chellappan SP, Mudryj M, Hiebert S, Devoto S, Horowitz J, Hunter T, Pines J. E2F transcription factor is a target for the RB protein and the cyclin A protein Cold Spring Harbor Symposia On Quantitative Biology. 56: 157-162. PMID 1840249 DOI: 10.1101/Sqb.1991.056.01.020  0.338
1991 Hunter T. Protein kinase classification. Methods in Enzymology. 200: 3-37. PMID 1835513 DOI: 10.1016/0076-6879(91)00125-G  0.436
1991 Mudryj M, Devoto SH, Hiebert SW, Hunter T, Pines J, Nevins JR. Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A Cell. 65: 1243-1253. PMID 1829647 DOI: 10.1016/0092-8674(91)90019-U  0.312
1991 Pines J, Hunter T. Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. The Journal of Cell Biology. 115: 1-17. PMID 1717476 DOI: 10.1016/0962-8924(92)90129-B  0.342
1991 Jähner D, Hunter T. The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts. Molecular and Cellular Biology. 11: 3682-90. PMID 1710770 DOI: 10.1128/Mcb.11.7.3682  0.38
1991 van der Geer P, Hunter T. Tyrosine 706 and 807 phosphorylation site mutants in the murine colony-stimulating factor-1 receptor are unaffected in their ability to bind or phosphorylate phosphatidylinositol-3 kinase but show differential defects in their ability to induce early response gene transcription. Molecular and Cellular Biology. 11: 4698-709. PMID 1652061 DOI: 10.1128/Mcb.11.9.4698  0.381
1991 Soppet D, Escandon E, Maragos J, Middlemas DS, Reid SW, Blair J, Burton LE, Stanton BR, Kaplan DR, Hunter T, Nikolics K, Parada LF. The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor. Cell. 65: 895-903. PMID 1645620 DOI: 10.1016/0092-8674(91)90396-G  0.353
1991 Nishitani H, Ohtsubo M, Yamashita K, Iida H, Pines J, Yasudo H, Shibata Y, Hunter T, Nishimoto T. Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis. The Embo Journal. 10: 1555-1564. DOI: 10.1002/J.1460-2075.1991.Tb07675.X  0.404
1990 Bull P, Hunter T, Verma IM. Transcriptional induction of the murine c-rel gene with serum and phorbol-12-myristate-13-acetate in fibroblasts. Molecular and Cellular Biology. 9: 5239-43. PMID 2601720 DOI: 10.1128/Mcb.9.11.5239  0.47
1990 Hunter T. Protein modification: phosphorylation on tyrosine residues. Current Opinion in Cell Biology. 1: 1168-81. PMID 2561455 DOI: 10.1016/S0955-0674(89)80068-7  0.433
1990 Bull P, Morley KL, Hoekstra MF, Hunter T, Verma IM. The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain. Molecular and Cellular Biology. 10: 5473-85. PMID 2204816 DOI: 10.1128/Mcb.10.10.5473  0.531
1990 Isacke CM, van der Geer P, Hunter T, Trowbridge IS. p180, a novel recycling transmembrane glycoprotein with restricted cell type expression. Molecular and Cellular Biology. 10: 2606-18. PMID 2188094 DOI: 10.1128/Mcb.10.6.2606  0.379
1990 van der Geer P, Hunter T. Identification of tyrosine 706 in the kinase insert as the major colony-stimulating factor 1 (CSF-1)-stimulated autophosphorylation site in the CSF-1 receptor in a murine macrophage cell line. Molecular and Cellular Biology. 10: 2991-3002. PMID 2160591 DOI: 10.1128/Mcb.10.6.2991  0.38
1990 Pines J, Hunter T. Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B. Nature. 346: 760-3. PMID 2143810 DOI: 10.1038/346760A0  0.413
1990 Amiguet P, D'Eustachio P, Kristensen T, Wetsel RA, Saris CJ, Hunter T, Chaplin DD, Tack BF. Structure and chromosome assignment of the murine p36 (calpactin I heavy chain) gene. Biochemistry. 29: 1226-32. PMID 2138915 DOI: 10.1021/Bi00457A019  0.336
1990 Yamashita K, Yasuda H, Pines J, Yasumoto K, Nishitani H, Ohtsubo M, Hunter T, Sugimura T, Nishimoto T. Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells. The Embo Journal. 9: 4331-4338. DOI: 10.1002/J.1460-2075.1990.Tb07882.X  0.426
1989 Hunter T. The Ca2+/phospholipid-binding proteins of the submembraneous skeleton. Advances in Experimental Medicine and Biology. 234: 169-93. PMID 3063085 DOI: 10.1007/978-1-4757-1980-2_12  0.364
1989 Pines J, Hunter T. Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2. Cell. 58: 833-46. PMID 2570636 DOI: 10.1016/0092-8674(89)90936-7  0.363
1989 Defize LH, Boonstra J, Meisenhelder J, Kruijer W, Tertoolen LG, Tilly BC, Hunter T, van Bergen en Henegouwen PM, Moolenaar WH, de Laat SW. Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors. The Journal of Cell Biology. 109: 2495-507. PMID 2553748 DOI: 10.1083/Jcb.109.5.2495  0.589
1989 Hunter T. Protein-tyrosine phosphatases: the other side of the coin. Cell. 58: 1013-6. PMID 2550140 DOI: 10.1016/0092-8674(89)90496-0  0.4
1989 Hunter T. The functions of oncogene products. Progress in Clinical and Biological Research. 288: 25-34. PMID 2541449 DOI: 10.1007/978-1-4684-5009-5_4  0.311
1989 Meisenhelder J, Suh PG, Rhee SG, Hunter T. Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro. Cell. 57: 1109-22. PMID 2472219 DOI: 10.1016/0092-8674(89)90048-2  0.404
1989 Isacke CM, Lindberg RA, Hunter T. Synthesis of p36 and p35 is increased when U-937 cells differentiate in culture but expression is not inducible by glucocorticoids. Molecular and Cellular Biology. 9: 232-40. PMID 2467187 DOI: 10.1128/Mcb.9.1.232  0.359
1989 Gould KL, Bilezikjian LM, Hunter T. AtT20 cells express modified forms of pp60(c-src) Molecular Endocrinology. 3: 79-88. PMID 2464757 DOI: 10.1210/Mend-3-1-79  0.358
1989 Gould K, Bretscher A, Esch F, Hunter T. cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1. The Embo Journal. 8: 4133-4142. DOI: 10.1002/J.1460-2075.1989.Tb08598.X  0.366
1989 Freed E, Gailit J, van der Geer P, Ruoslahti E, Hunter T. A novel integrin beta subunit is associated with the vitronectin receptor alpha subunit (alpha v) in a human osteosarcoma cell line and is a substrate for protein kinase C. The Embo Journal. 8: 2955-2965. DOI: 10.1002/J.1460-2075.1989.Tb08445.X  0.345
1988 Angel P, Allegretto EA, Okino ST, Hattori K, Boyle WJ, Hunter T, Karin M. Oncogene jun encodes a sequence-specific trans-activator similar to AP-1. Nature. 332: 166-71. PMID 3347253 DOI: 10.1038/332166A0  0.353
1988 Hanks SK, Quinn AM, Hunter T. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science (New York, N.Y.). 241: 42-52. PMID 3291115 DOI: 10.1126/Science.3291115  0.415
1988 Chiu R, Boyle WJ, Meek J, Smeal T, Hunter T, Karin M. The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell. 54: 541-52. PMID 3135940 DOI: 10.1016/0092-8674(88)90076-1  0.334
1988 Hunter T, Angel P, Boyle WJ, Chiu R, Freed E, Gould KL, Isacke CM, Karin M, Lindberg RA, van der Geer P. Targets for signal-transducing protein kinases. Cold Spring Harbor Symposia On Quantitative Biology. 53: 131-42. PMID 3076078 DOI: 10.1101/Sqb.1988.053.01.019  0.58
1988 Weinmaster GA, Hunter T. Investigation of the role of P130gag-fps in transformation: generation and use of a temperature-sensitive mutant P130gag-fps. Journal of Virology. 62: 3849-54. PMID 2843679 DOI: 10.1128/Jvi.62.10.3849-3854.1988  0.377
1988 Gould KL, Hunter T. Platelet-derived growth factor induces multisite phosphorylation of pp60(c-src) and increases its protein-tyrosine kinase activity Molecular and Cellular Biology. 8: 3345-3356. PMID 2463476 DOI: 10.1128/Mcb.8.8.3345  0.436
1988 Defize LH, Arndt-Jovin DJ, Jovin TM, Boonstra J, Meisenhelder J, Hunter T, de Hey HT, de Laat SW. A431 cell variants lacking the blood group A antigen display increased high affinity epidermal growth factor-receptor number, protein-tyrosine kinase activity, and receptor turnover. The Journal of Cell Biology. 107: 939-49. PMID 2458364 DOI: 10.1083/Jcb.107.3.939  0.614
1988 Cartwright CA, Simantov R, Cowan WM, Hunter T, Eckhart W. pp60c-src expression in the developing rat brain. Proceedings of the National Academy of Sciences of the United States of America. 85: 3348-52. PMID 2453056 DOI: 10.1073/Pnas.85.10.3348  0.653
1988 Weinmaster GA, Middlemas DS, Hunter T. A major site of tyrosine phosphorylation within the SH2 domain of Fujinami sarcoma virus P130gag-fps is not required for protein-tyrosine kinase activity or transforming potential. Journal of Virology. 62: 2016-25. PMID 2452898 DOI: 10.1128/Jvi.62.6.2016-2025.1988  0.452
1987 Woodgett JR, Hunter T. Immunological evidence for two physiological forms of protein kinase C Molecular and Cellular Biology. 7: 85-96. PMID 3561403 DOI: 10.1128/Mcb.7.1.85  0.427
1987 Bilezikjian LM, Woodgett JR, Hunter T, Vale WW. Phorbol ester-induced down-regulation of protein kinase C abolishes vasopressin-mediated responses in rat anterior pituitary cells Molecular Endocrinology (Baltimore, Md.). 1: 555-560. PMID 3153477 DOI: 10.1210/Mend-1-8-555  0.378
1987 Hunter T. A thousand and one protein kinases. Cell. 50: 823-9. PMID 3113737 DOI: 10.1016/0092-8674(87)90509-5  0.428
1987 Isacke CM, Trowbridge IS, Hunter T. Modulation of p36 phosphorylation in human cells: studies using anti-p36 monoclonal antibodies. Molecular and Cellular Biology. 6: 2745-51. PMID 2946941 DOI: 10.1128/Mcb.6.7.2745  0.374
1987 Cartwright CA, Simantov R, Kaplan PL, Hunter T, Eckhart W. Alterations in pp60c-src accompany differentiation of neurons from rat embryo striatum. Molecular and Cellular Biology. 7: 1830-40. PMID 2439897 DOI: 10.1128/Mcb.7.5.1830  0.662
1986 Cooper JA, Hunter T. Major substrate for growth factor-activated protein-tyrosine kinases is a low-abundance protein. Molecular and Cellular Biology. 5: 3304-9. PMID 3879813 DOI: 10.1128/Mcb.5.11.3304  0.42
1986 Tripp ML, Piñon R, Meisenhelder J, Hunter T. Identification of phosphoproteins correlated with proliferation and cell cycle arrest in Saccharomyces cerevisiae: positive and negative regulation by cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 83: 5973-7. PMID 3526346 DOI: 10.1073/Pnas.83.16.5973  0.452
1986 Woodgett JR, Gould KL, Hunter T. Substrate specificity of protein kinase C - Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements European Journal of Biochemistry. 161: 177-184. PMID 3023081 DOI: 10.1111/J.1432-1033.1986.Tb10139.X  0.449
1986 Saris CJ, Tack BF, Kristensen T, Glenney JR, Hunter T. The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats. Cell. 46: 201-12. PMID 3013423 DOI: 10.1016/0092-8674(86)90737-3  0.379
1986 Hunter T, Alexander CB, Cooper JA. Protein phosphorylation and growth control. Ciba Foundation Symposium. 116: 188-204. PMID 3000705 DOI: 10.1002/9780470720974.ch12  0.347
1986 Gould KL, Woodgett JR, Isacke CM, Hunter T. The protein-tyrosine kinase substrate p36 is also a substrate for protein kinase C in vitro and in vivo Molecular and Cellular Biology. 6: 2738-2744. PMID 2946940 DOI: 10.1128/mcb.6.7.2738-2744.1986  0.439
1986 Kristensen T, Saris CJM, Hunter T, Hicks LJ, Noonan DJ, Glenney JR, Tack BF. Primary structure of bovine calpactin I heavy chain (p36), a major cellular substrate for retroviral protein-tyrosine kinases: homology with the human phospholipase A2 inhibitor lipocortin Biochemistry®. 25: 4497-4503. PMID 2945590 DOI: 10.1021/Bi00364A007  0.328
1986 Cartwright CA, Kaplan PL, Cooper JA, Hunter T, Eckhart W. Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen. Molecular and Cellular Biology. 6: 1562-70. PMID 2431281 DOI: 10.1128/Mcb.6.5.1562  0.691
1986 Sefton BM, Hunter T. From c-src to v-src, or the case of the missing C terminus. Cancer Surveys. 5: 159-72. PMID 2430701  0.353
1986 Patschinsky T, Hunter T, Sefton BM. Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virus. Journal of Virology. 59: 73-81. PMID 2423705 DOI: 10.1128/Jvi.59.1.73-81.1986  0.437
1986 Cooper JA, Gould KL, Cartwright CA, Hunter T. Tyr527 is phosphorylated in pp60c-src: Implications for regulation Science. 231: 1431-1434. PMID 2420005 DOI: 10.1126/Science.2420005  0.457
1986 Gould KL, Cooper JA, Bretscher A, Hunter T. The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein Journal of Cell Biology. 102: 660-669. PMID 2418035 DOI: 10.1083/Jcb.102.2.660  0.372
1986 Hunter T, Cooper JA. 6 Viral Oncogenes and Tyrosine Phosphorylation The Enzymes. 17: 191-246. DOI: 10.1016/S1874-6047(08)60431-X  0.456
1986 Isacke C, Meisenhelder J, Brown K, Gould K, Gould S, Hunter T. Early phosphorylation events following the treatment of Swiss 3T3 cells with bombesin and the mammalian bombesin-related peptide, gastrin-releasing peptide. The Embo Journal. 5: 2889-2898. DOI: 10.1002/J.1460-2075.1986.Tb04584.X  0.432
1985 Kruijer W, Cooper JA, Hunter T, Verma IM. Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein. Nature. 312: 711-6. PMID 6514007 DOI: 10.1038/312711A0  0.482
1985 Gould KL, Woodgett JR, Cooper JA, Buss JE, Shalloway D, Hunter T. Protein kinase C phosphorylates pp60src at a novel site Cell. 42: 849-857. PMID 2996780 DOI: 10.1016/0092-8674(85)90281-8  0.632
1985 Hunter T, Cooper JA. Protein-tyrosine kinases. Annual Review of Biochemistry. 54: 897-930. PMID 2992362 DOI: 10.1146/  0.318
1985 Coussens PM, Cooper JA, Hunter T, Shalloway D. Restriction of the in vitro and in vivo tyrosine protein kinase activities of pp60(c-src) relative to pp60(v-src) Molecular and Cellular Biology. 5: 2753-2763. PMID 2426575 DOI: 10.1128/Mcb.5.10.2753  0.48
1985 Hunter T. Oncogenes and growth control Trends in Biochemical Sciences. 10: 275-280. DOI: 10.1016/0968-0004(85)90087-8  0.307
1984 Hunter T, Cooper JA. Role of tyrosine phosphorylation in malignant transformation by viruses and in cellular growth control. Progress in Nucleic Acid Research and Molecular Biology. 29: 221-32. PMID 6686688 DOI: 10.1016/S0079-6603(08)60450-X  0.458
1984 Voronova AF, Buss JE, Patschinsky T, Hunter T, Sefton BM. Characterization of the protein apparently responsible for the elevated tyrosine protein kinase activity in LSTRA cells. Molecular and Cellular Biology. 4: 2705-13. PMID 6543243 DOI: 10.1128/Mcb.4.12.2705  0.474
1984 Hunter T, Gould KL, Cooper JA. Tyrosine protein kinases, viral transformation and the control of cell proliferation Biochemical Society Transactions. 12: 757-759. PMID 6437890 DOI: 10.1042/Bst0120757  0.429
1984 Cooper JA, Hunter T. Regulation of cell growth and transformation by tyrosine-specific protein kinases: the search for important cellular substrate proteins. Current Topics in Microbiology and Immunology. 107: 125-61. PMID 6421545 DOI: 10.1007/978-3-642-69075-4_4  0.468
1984 Papkoff J, Nigg EA, Hunter T. The transforming protein of Moloney murine sarcoma virus is a soluble cytoplasmic protein. Cell. 33: 161-72. PMID 6380747 DOI: 10.1016/0092-8674(83)90345-8  0.361
1984 Cooper JA, Esch FS, Taylor SS, Hunter T. Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinase in vivo and in vitro Journal of Biological Chemistry. 259: 7835-7841. PMID 6330085  0.344
1984 Donoghue DJ, Anderson C, Hunter T, Kaplan PL. Transmission of the polyoma virus middle T gene as the oncogene of a murine retrovirus. Nature. 308: 748-50. PMID 6325917 DOI: 10.1038/308748A0  0.542
1984 Gould KL, Cooper JA, Hunter T. The 46,000-dalton tyrosine protein kinase substrate is widespread, whereas the 36,000-dalton substrate is only expressed at high levels in certain rodent tissues Journal of Cell Biology. 98: 487-497. PMID 6319429 DOI: 10.1083/Jcb.98.2.487  0.33
1984 Hunter T. The proteins of oncogenes. Scientific American. 251: 70-79. PMID 6206561 DOI: 10.1038/Scientificamerican0884-70  0.344
1984 Cooper JA, Sefton BM, Hunter T. Diverse mitogenic agents induce the phosphorylation of two related 42,000-dalton proteins on tyrosine in quiescent chick cells. Molecular and Cellular Biology. 4: 30-7. PMID 6199661 DOI: 10.1128/Mcb.4.1.30  0.457
1984 Sefton BM, Hunter T. Tyrosine protein kinases. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 18: 195-226. PMID 6093480  0.318
1984 Hunter T, Ling N, Cooper JA. Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane. Nature. 311: 480-3. PMID 6090944 DOI: 10.1038/311480A0  0.465
1984 Hunter T, Hutchinson M, Eckhart W. Polyoma middle-sized T antigen can be phosphorylated on tyrosine at multiple sites in vitro. The Embo Journal. 3: 73-79. DOI: 10.1002/J.1460-2075.1984.Tb01763.X  0.668
1983 Nigg EA, Cooper JA, Hunter T. Immunofluorescent localization of a 39,000-dalton substrate of tyrosine protein kinases to the cytoplasmic surface of the plasma membrane. The Journal of Cell Biology. 96: 1601-9. PMID 6304112 DOI: 10.1083/Jcb.96.6.1601  0.338
1983 Papkoff J, Hunter T. Detection of an 85,000-dalton phosphoprotein in ts110 murine sarcoma virus-infected cells with antiserum against a v-mos peptide. Journal of Virology. 45: 1177-1182. PMID 6300455 DOI: 10.1128/Jvi.45.3.1177-1182.1983  0.339
1983 Donoghue DJ, Hunter T. Recombinational junctions of variants of Moloney murine sarcoma virus: generation and divergence of a mammalian transforming gene. Journal of Virology. 45: 607-17. PMID 6300424 DOI: 10.1128/Jvi.45.2.607-617.1983  0.532
1983 Sefton BM, Hunter T, Cooper JA. Some lymphoid cell lines transformed by Abelson murine leukemia virus lack a major 36,000-dalton tyrosine protein kinase substrate. Molecular and Cellular Biology. 3: 56-63. PMID 6298608 DOI: 10.1128/Mcb.3.1.56  0.417
1983 Cooper JA, Sefton BM, Hunter T. Detection and quantification of phosphotyrosine in proteins. Methods in Enzymology. 99: 387-402. PMID 6196603 DOI: 10.1016/0076-6879(83)99075-4  0.46
1983 Cooper JA, Reiss NA, Schwartz RJ, Hunter T. Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus. Nature. 302: 218-23. PMID 6188054 DOI: 10.1038/302218A0  0.435
1983 Cooper J, Nakamura KD, Hunter T, Weber MJ. Phosphotyrosine-containing proteins and expression of transformation parameters in cells infected with partial transformation mutants of Rous sarcoma virus. Journal of Virology. 46: 15-28. PMID 6186822 DOI: 10.1128/Jvi.46.1.15-28.1983  0.434
1983 Cooper JA, Bowen-Pope DF, Raines E, Ross R, Hunter T. Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins. Cell. 31: 263-73. PMID 6186382 DOI: 10.1016/0092-8674(82)90426-3  0.393
1983 Cooper JA, Scolnick EM, Ozanne B, Hunter T. Epidermal growth factor receptor metabolism and protein kinase activity in human A431 cells infected with Snyder-Theilen feline sarcoma virus or harvey or Kirsten murine sarcoma virus. Journal of Virology. 48: 752-764. DOI: 10.1128/Jvi.48.3.752-764.1983  0.38
1983 HUNTER T, COOPER J. Is tyrosine phosphorylation involved in growth control? Cell Biology International Reports. 7: 505-506. DOI: 10.1016/0309-1651(83)90150-9  0.337
1983 Kiberstis PA, Pessi A, Atherton E, Jackson R, Hunter T, Zimmern D. Analysis of in vitro and in vivo products of the TMV 30kDa open reading frame using antisera raised against a synthetic peptide Febs Letters. 164: 355-360. DOI: 10.1016/0014-5793(83)80316-0  0.322
1982 Hunter T. Phosphotyrosine - a new protein modification. Trends in Biochemical Sciences. 7: 246-249. PMID 31413447 DOI: 10.1016/0968-0004(82)90035-4  0.454
1982 Sefton BM, Hunter T, Nigg EA, Singer SJ, Walter G. Cytoskeletal targets for viral transforming proteins with tyrosine protein kinase activity. Cold Spring Harbor Symposia On Quantitative Biology. 46: 939-51. PMID 6809406 DOI: 10.1101/Sqb.1982.046.01.088  0.425
1982 Papkoff J, Lai MH, Hunter T. Analysis of v-mos encoded proteins in cells transformed by several related murine sarcoma viruses. Journal of Cellular Biochemistry. 19: 349-62. PMID 6298255 DOI: 10.1002/Jcb.240190405  0.353
1982 Nigg EA, Sefton BM, Hunter T, Walter G, Singer SJ. Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide. Proceedings of the National Academy of Sciences of the United States of America. 79: 5322-6. PMID 6291037 DOI: 10.1073/Pnas.79.17.5322  0.36
1982 Adkins B, Hunter T. Two structurally and functionally different forms of the transforming protein of PRC II avian sarcoma virus Molecular and Cellular Biology. 2: 890-896. PMID 6290871 DOI: 10.1128/Mcb.2.8.890  0.324
1982 Papkoff J, Verma IM, Hunter T. Detection of a transforming gene product in cells transformed by Moloney murine sarcoma virus. Cell. 29: 417-26. PMID 6288258 DOI: 10.1016/0092-8674(82)90158-1  0.54
1982 Walter G, Hutchinson MA, Hunter T, Eckhart W. Purification of polyoma virus medium-size tumor antigen by immunoaffinity chromatography. Proceedings of the National Academy of Sciences of the United States of America. 79: 4025-9. PMID 6287461 DOI: 10.1073/Pnas.79.13.4025  0.637
1982 Adkins B, Hunter T, Beemon K. Expression of the PRC II avian sarcoma virus genome Journal of Virology. 41: 767-780. PMID 6284969 DOI: 10.1128/Jvi.41.3.767-780.1982  0.634
1982 Donoghue DJ, Hunter T. A generalized method of subcloning DNA fragments by restriction site reconstruction: application to sequencing the amino-terminal coding region of the transforming gene of Gazdar murine sarcoma virus. Nucleic Acids Research. 10: 2549-64. PMID 6281735 DOI: 10.1093/Nar/10.8.2549  0.544
1982 Patschinsky T, Hunter T, Esch FS, Cooper JA, Sefton BM. Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 79: 973-7. PMID 6280176 DOI: 10.1073/Pnas.79.4.973  0.444
1982 Hunter T. Synthetic peptide substrates for a tyrosine protein kinase. The Journal of Biological Chemistry. 257: 4843-8. PMID 6279650  0.309
1982 Donoghue DJ, Hunter T. Expression of transforming region of Moloney murine sarcoma virus in Escherichia coli as a fusion protein with small tumor antigen of polyoma virus. Proceedings of the National Academy of Sciences of the United States of America. 79: 800-4. PMID 6278495 DOI: 10.1073/Pnas.79.3.800  0.579
1982 Papkoff J, Lai MH, Hunter T, Verma IM. Analysis of transforming gene products from Moloney murine sarcoma virus. Cell. 27: 109-19. PMID 6276018 DOI: 10.1016/0092-8674(81)90365-2  0.497
1982 Adkins B, Hunter T, Sefton BM. The transforming proteins of PRCII virus and Rous sarcoma virus form a complex with the same two cellular phosphoproteins. Journal of Virology. 43: 448-55. PMID 6180178 DOI: 10.1128/Jvi.43.2.448-455.1982  0.406
1982 Cooper JA, Hunter T. Discrete primary locations of a tyrosine-protein kinase and of three proteins that contain phosphotyrosine in virally transformed chick fibroblasts. The Journal of Cell Biology. 94: 287-96. PMID 6179948 DOI: 10.1083/Jcb.94.2.287  0.437
1982 Sefton BM, Patschinsky T, Berdot C, Hunter T, Elliott T. Phosphorylation and metabolism of the transforming protein of Rous sarcoma virus. Journal of Virology. 41: 813-20. PMID 6178840 DOI: 10.1128/Jvi.41.3.813-820.1982  0.387
1981 Walter G, Hutchinson MA, Hunter T, Eckhart W. Antibodies specific for the polyoma virus middle-size tumor antigen. Proceedings of the National Academy of Sciences of the United States of America. 78: 4882-6. PMID 6272281 DOI: 10.1073/Pnas.78.8.4882  0.624
1981 Sefton BM, Hunter T, Ball EH, Singer SJ. Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus. Cell. 24: 165-74. PMID 6263485 DOI: 10.1016/0092-8674(81)90512-2  0.402
1981 Sefton BM, Hunter T, Raschke WC. Evidence that the Abelson virus protein functions in vivo as a protein kinase that phosphorylates tyrosine. Proceedings of the National Academy of Sciences of the United States of America. 78: 1552-6. PMID 6262813 DOI: 10.1073/Pnas.78.3.1552  0.445
1981 Eckhart W, Delbrück S, Deininger P, Friedmann T, Hunter T. A mutation increasing the size of the polyoma virion proteins, VP2 and VP3. Virology. 109: 35-46. PMID 6258312 DOI: 10.1016/0042-6822(81)90469-4  0.635
1981 Hunter T. Protein phosphorylated by the RSV transforming function. Cell. 22: 647-8. PMID 6257393 DOI: 10.1016/0092-8674(80)90539-5  0.382
1981 Cooper JA, Hunter T. Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus. The Journal of Cell Biology. 91: 878-83. PMID 6173387 DOI: 10.1083/Jcb.91.3.878  0.419
1981 Hunter T, Cooper JA. Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells. Cell. 24: 741-52. PMID 6166387 DOI: 10.1016/0092-8674(81)90100-8  0.371
1981 Cooper JA, Hunter T. Changes in protein phosphorylation in Rous sarcoma virus-transformed chicken embryo cells. Molecular and Cellular Biology. 1: 165-78. PMID 6100962 DOI: 10.1128/Mcb.1.2.165  0.424
1981 Cooper JA, Hunter T. Four different classes of retroviruses induce phosphorylation of tyrosines present in similar cellular proteins. Molecular and Cellular Biology. 1: 394-407. PMID 6086011 DOI: 10.1128/Mcb.1.5.394  0.392
1980 Papkoff J, Hunter T, Beemon K. In vitro translation of virion RNA from Moloney murine sarcoma virus Virology. 101: 91-103. PMID 7355580 DOI: 10.1016/0042-6822(80)90486-9  0.606
1980 Hunter T, Sefton BM, Beemon K. Studies on the structure and function of the avian sarcoma virus transforming-gene product. Cold Spring Harbor Symposia On Quantitative Biology. 44: 931-41. PMID 6253224 DOI: 10.1101/Sqb.1980.044.01.100  0.69
1980 Hunter T, Hutchinson MA, Eckhart W, Friedmann T, Esty A, La Porte P, Deininger P. Organization of T antigens in the polyoma virus genome. Cold Spring Harbor Symposia On Quantitative Biology. 44: 131-9. PMID 6253126 DOI: 10.1101/Sqb.1980.044.01.015  0.587
1980 Sefton BM, Hunter T, Beemon K, Eckhart W. Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus. Cell. 20: 807-16. PMID 6251974 DOI: 10.1016/0092-8674(80)90327-X  0.759
1980 Sefton BM, Hunter T, Beemon K. Relationship of polypeptide products of the transforming gene of Rous sarcoma virus and the homologous gene of vertebrates. Proceedings of the National Academy of Sciences of the United States of America. 77: 2059-63. PMID 6246520 DOI: 10.1073/Pnas.77.4.2059  0.622
1980 Hunter T, Sefton BM. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proceedings of the National Academy of Sciences of the United States of America. 77: 1311-5. PMID 6246487 DOI: 10.1073/Pnas.77.3.1311  0.475
1980 Sefton BM, Hunter T, Beemon K. Temperature-sensitive transformation by Rous sarcoma virus and temperature-sensitive protein kinase activity. Journal of Virology. 33: 220-9. PMID 6245228 DOI: 10.1128/Jvi.33.1.220-229.1980  0.687
1979 Lawrence C, Hunter T, Walter G. Characterization of the simian virus 40-specific messenger RNAs isolated from HeLa cells infected with the non-defective adenovirus 2-simian virus 40 hybrid viruses Ad2+ND2 and Ad2+ND4. Journal of Molecular Biology. 134: 95-108. PMID 231666 DOI: 10.1016/0022-2836(79)90415-7  0.37
1979 Hunter T, Hutchinson MA, Eckhart W, Friedmann T, Esty A, LaPorte P, Deininger P. Regions of the polyoma genome coding for T antigens. Nucleic Acids Research. 7: 2275-88. PMID 230465 DOI: 10.1093/Nar/7.8.2275  0.6
1979 Eckhart W, Hutchinson MA, Hunter T. An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates. Cell. 18: 925-33. PMID 229973 DOI: 10.1016/0092-8674(79)90205-8  0.66
1979 Sefton BM, Hunter T, Beemon K. Product of in vitro translation of the Rous sarcoma virus src gene has protein kinase activity. Journal of Virology. 30: 311-8. PMID 225522 DOI: 10.1128/Jvi.30.1.311-318.1979  0.7
1979 Beemon K, Hunter T, Sefton BM. Polymorphism of avian sarcoma virus src proteins. Journal of Virology. 30: 190-200. PMID 225515 DOI: 10.1128/Jvi.30.1.190-200.1979  0.622
1978 Hunter T, Hutchinson MA, Eckhart W. Translation of polyoma virus T antigens in vitro. Proceedings of the National Academy of Sciences of the United States of America. 75: 5917-21. PMID 216001 DOI: 10.1073/Pnas.75.12.5917  0.621
1978 Sefton BM, Beemon K, Hunter T. Comparison of the expression of the src gene of Rous sarcoma virus in vitro and in vivo. Journal of Virology. 28: 957-71. PMID 215787 DOI: 10.1128/Jvi.28.3.957-971.1978  0.639
1978 Beemon K, Hunter T. Characterization of Rous sarcoma virus src gene products synthesized in vitro Journal of Virology. 28: 551-566. PMID 214578 DOI: 10.1128/Jvi.28.2.551-566.1978  0.608
1978 Hunter T, Gibson W. Characterization of the mRNA's for the polyoma virus capsid proteins VP1, VP2, and VP3 Journal of Virology. 28: 240-253. PMID 212604 DOI: 10.1128/Jvi.28.1.240-253.1978  0.334
1978 Hutchinson MA, Hunter T, Eckhart W. Characterization of T antigens in polyoma-infected and transformed cells. Cell. 15: 65-77. PMID 212199 DOI: 10.1016/0092-8674(78)90083-1  0.584
1977 Beemon K, Hunter T. In vitro translation yields a possible Rous sarcoma virus src gene product Proceedings of the National Academy of Sciences of the United States of America. 74: 3302-3306. PMID 198780 DOI: 10.1073/Pnas.74.8.3302  0.639
1977 Mann K, Hunter T, Walter G, Linke H. Evidence for simian virus 40 (SV40) coding of SV40 T-antigen and the SV40-specific proteins in HeLa cells infected with nondefective adenovirus type 2-SV40 hybrid viruses. Journal of Virology. 24: 151-169. PMID 198574 DOI: 10.1128/Jvi.24.1.151-169.1977  0.349
1977 Gibson W, Hunter T, Cogen B, Eckhart W. Altered virion proteins of a temperature-sensitive mutant of polyoma virus, ts59. Virology. 80: 21-41. PMID 195395 DOI: 10.1016/0042-6822(77)90378-6  0.641
1972 Hunt T, Hunter T, Munro A. Control of haemoglobin synthesis: distribution of ribosomes on the messenger RNA for alpha and beta chains. Journal of Molecular Biology. 36: 31-45. PMID 5760537 DOI: 10.1016/0022-2836(68)90217-9  0.455
1969 Hunt T, Hunter T, Munro A. Control of haemoglobin synthesis: rate of translation of the messenger RNA for the alpha and beta chains. Journal of Molecular Biology. 43: 123-33. PMID 5811817 DOI: 10.1016/0022-2836(69)90083-7  0.425
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