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Tony Hunter - Publications

Salk Institute for Biological Studies, La Jolla, CA, United States 
growth control and cell cycle regulation

164 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, ... ... Hunter T, et al. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. PMID 31327527 DOI: 10.1016/j.cell.2019.06.024  0.56
2018 Zhu Q, Hoong N, Aslanian A, Hara T, Benner C, Heinz S, Miga KH, Ke E, Verma S, Soroczynski J, Yates JR, Hunter T, Verma IM. Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer. Molecular Cell. PMID 29861157 DOI: 10.1016/j.molcel.2018.04.023  0.56
2016 Zheng X, Boyer L, Jin M, Mertens J, Kim Y, Ma L, Ma L, Hamm M, Gage FH, Hunter T. Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation. Elife. 5. PMID 27282387 DOI: 10.7554/eLife.13374  1
2016 Zheng X, Boyer L, Jin M, Kim Y, Fan W, Bardy C, Berggren T, Evans RM, Gage FH, Hunter T. Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration. Elife. 5. PMID 27008180 DOI: 10.7554/eLife.13378  1
2016 Li X, Jiang Y, Meisenhelder J, Yang W, Hawke DH, Zheng Y, Xia Y, Aldape K, He J, Hunter T, Wang L, Lu Z. Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis. Molecular Cell. 61: 705-719. PMID 26942675 DOI: 10.1016/j.molcel.2016.02.009  0.4
2015 Heimbucher T, Hunter T. The C. elegans Ortholog of USP7 controls DAF-16 stability in Insulin/IGF-1-like signaling. Worm. 4: e1103429. PMID 27123371 DOI: 10.1080/21624054.2015.1103429  1
2015 Heimbucher T, Liu Z, Bossard C, McCloskey R, Carrano AC, Riedel CG, Tanasa B, Klammt C, Fonslow BR, Riera CE, Lillemeier BF, Kemphues K, Yates JR, O'Shea C, Hunter T, et al. The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity. Cell Metabolism. 22: 151-63. PMID 26154057 DOI: 10.1016/j.cmet.2015.06.002  1
2015 Fuhs SR, Meisenhelder J, Aslanian A, Ma L, Zagorska A, Stankova M, Binnie A, Al-Obeidi F, Mauger J, Lemke G, Yates JR, Hunter T. Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation. Cell. 162: 198-210. PMID 26140597 DOI: 10.1016/j.cell.2015.05.046  1
2015 Hunter T. Discovering the first tyrosine kinase. Proceedings of the National Academy of Sciences of the United States of America. 112: 7877-82. PMID 26130799 DOI: 10.1073/pnas.1508223112  1
2015 Puto LA, Benner C, Hunter T. The DAXX co-repressor is directly recruited to active regulatory elements genome-wide to regulate autophagy programs in a model of human prostate cancer. Oncoscience. 2: 362-72. PMID 26097870 DOI: 10.18632/oncoscience.152  1
2015 Carrano AC, Hunter T. Fitting WWP-1 in the dietary restriction network. Cell Cycle (Georgetown, Tex.). 14: 1485-6. PMID 25941993 DOI: 10.1080/15384101.2015.1032642  1
2015 Carrano AC, Hunter T. Fitting wwp-1 in the dietary restriction network. Cell Cycle (Georgetown, Tex.). 0. PMID 25790270 DOI: 10.1080/15384101.2015.1026516  0.52
2015 Wilkinson DS, Jariwala JS, Anderson E, Mitra K, Meisenhelder J, Chang JT, Ideker T, Hunter T, Nizet V, Dillin A, Hansen M. Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy. Molecular Cell. 57: 55-68. PMID 25544559 DOI: 10.1016/j.molcel.2014.11.019  0.52
2015 Hunter T, Manning G. The eukaryotic protein kinase superfamily and the emergence of receptor tyrosine kinases Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease. 1-15. DOI: 10.1007/978-1-4939-2053-2_1  1
2014 Yang W, Xia Y, Hawke D, Li X, Liang J, Xing D, Aldape K, Hunter T, Yung WKA, Lu Z. PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis. Cell. 158: 1210. PMID 28917293 DOI: 10.1016/j.cell.2014.08.003  0.4
2014 Thorner J, Hunter T, Cantley LC, Sever R. Signal transduction: From the atomic age to the post-genomic era. Cold Spring Harbor Perspectives in Biology. 6: a022913. PMID 25359498 DOI: 10.1101/cshperspect.a022913  1
2014 Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, ... ... Hunter T, et al. Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy. Cell. 159: 80-93. PMID 25259922 DOI: 10.1016/j.cell.2014.08.007  1
2014 Lu Z, Hunter T. Prolyl isomerase Pin1 in cancer. Cell Research. 24: 1033-49. PMID 25124924 DOI: 10.1038/cr.2014.109  1
2014 Zheng X, Hunter T. Pink1, the first ubiquitin kinase. The Embo Journal. 33: 1621-3. PMID 24942162 DOI: 10.15252/embj.201489185  1
2014 Sun H, Liu Y, Hunter T. Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control. Molecular and Cellular Biology. 34: 2981-95. PMID 24912682 DOI: 10.1128/MCB.00036-14  1
2014 Carrano AC, Dillin A, Hunter T. A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans. Nature Communications. 5: 3772. PMID 24805825 DOI: 10.1038/ncomms4772  1
2014 Ma L, Aslanian A, Sun H, Jin M, Shi Y, Yates JR, Hunter T. Identification of small ubiquitin-like modifier substrates with diverse functions using the Xenopus egg extract system. Molecular & Cellular Proteomics : McP. 13: 1659-75. PMID 24797264 DOI: 10.1074/mcp.M113.035626  1
2014 Voog J, Sandall SL, Hime GR, Resende LP, Loza-Coll M, Aslanian A, Yates JR, Hunter T, Fuller MT, Jones DL. Escargot restricts niche cell to stem cell conversion in the Drosophila testis. Cell Reports. 7: 722-34. PMID 24794442 DOI: 10.1016/j.celrep.2014.04.025  1
2014 Hunter T. The genesis of tyrosine phosphorylation. Cold Spring Harbor Perspectives in Biology. 6: a020644. PMID 24789824 DOI: 10.1101/cshperspect.a020644  1
2014 Aslanian A, Yates JR, Hunter T. Mass spectrometry-based quantification of the cellular response to methyl methanesulfonate treatment in human cells. Dna Repair. 15: 29-38. PMID 24461736 DOI: 10.1016/j.dnarep.2013.12.007  1
2014 Ma H, Han BK, Guaderrama M, Aslanian A, Yates JR, Hunter T, Wittenberg C. Psy2 targets the PP4 family phosphatase Pph3 to dephosphorylate Mth1 and repress glucose transporter gene expression. Molecular and Cellular Biology. 34: 452-63. PMID 24277933 DOI: 10.1128/MCB.00279-13  1
2014 Zhang Y, Hunter T. Roles of Chk1 in cell biology and cancer therapy. International Journal of Cancer. Journal International Du Cancer. 134: 1013-23. PMID 23613359 DOI: 10.1002/ijc.28226  1
2013 Hunter T. Translating experience: thinking outside the box. Nature Cell Biology. 15: 545. PMID 23728459 DOI: 10.1038/ncb2771  1
2013 Zheng X, Hunter T. Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism. Cell Research. 23: 886-97. PMID 23670163 DOI: 10.1038/cr.2013.66  1
2012 Lu CS, Truong LN, Aslanian A, Shi LZ, Li Y, Hwang PY, Koh KH, Hunter T, Yates JR, Berns MW, Wu X. The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination. The Journal of Biological Chemistry. 287: 43984-94. PMID 23115235 DOI: 10.1074/jbc.M112.421545  1
2012 Sun H, Hunter T. Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string search. The Journal of Biological Chemistry. 287: 42071-83. PMID 23086935 DOI: 10.1074/jbc.M112.410985  1
2012 Zhang QC, Petrey D, Deng L, Qiang L, Shi Y, Thu CA, Bisikirska B, Lefebvre C, Accili D, Hunter T, Maniatis T, Califano A, Honig B. Structure-based prediction of protein-protein interactions on a genome-wide scale. Nature. 490: 556-60. PMID 23023127 DOI: 10.1038/nature11503  1
2012 Zhu W, Kuo D, Nathanson J, Satoh A, Pao GM, Yeo GW, Bryant SV, Voss SR, Gardiner DM, Hunter T. Retrotransposon long interspersed nucleotide element-1 (LINE-1) is activated during salamander limb regeneration. Development, Growth & Differentiation. 54: 673-85. PMID 22913491 DOI: 10.1111/j.1440-169X.2012.01368.x  1
2012 Yang W, Xia Y, Hawke D, Li X, Liang J, Xing D, Aldape K, Hunter T, Alfred Yung WK, Lu Z. PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis. Cell. 150: 685-96. PMID 22901803 DOI: 10.1016/j.cell.2012.07.018  1
2012 Hunter T. Why nature chose phosphate to modify proteins. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2513-6. PMID 22889903 DOI: 10.1098/rstb.2012.0013  1
2012 Hunter T, Pawson T. The evolution of protein phosphorylation. Preface. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2512. PMID 22889902 DOI: 10.1098/rstb.2012.0374  1
2012 Wang Z, Shah OJ, Hunter T. The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models. Plos One. 7: e36961. PMID 22859932 DOI: 10.1371/journal.pone.0036961  1
2012 Zhu W, Pao GM, Satoh A, Cummings G, Monaghan JR, Harkins TT, Bryant SV, Randal Voss S, Gardiner DM, Hunter T. Activation of germline-specific genes is required for limb regeneration in the Mexican axolotl. Developmental Biology. 370: 42-51. PMID 22841627 DOI: 10.1016/j.ydbio.2012.07.021  1
2012 Chaurushiya MS, Lilley CE, Aslanian A, Meisenhelder J, Scott DC, Landry S, Ticau S, Boutell C, Yates JR, Schulman BA, Hunter T, Weitzman MD. Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain. Molecular Cell. 46: 79-90. PMID 22405594 DOI: 10.1016/j.molcel.2012.02.004  1
2011 Brognard J, Zhang YW, Puto LA, Hunter T. Cancer-associated loss-of-function mutations implicate DAPK3 as a tumor-suppressing kinase. Cancer Research. 71: 3152-61. PMID 21487036 DOI: 10.1158/0008-5472.CAN-10-3543  1
2011 Brognard J, Hunter T. Protein kinase signaling networks in cancer. Current Opinion in Genetics & Development. 21: 4-11. PMID 21123047 DOI: 10.1016/j.gde.2010.10.012  1
2010 Olson BJ, Oberholzer M, Li Y, Zones JM, Kohli HS, Bisova K, Fang SC, Meisenhelder J, Hunter T, Umen JG. Regulation of the Chlamydomonas cell cycle by a stable, chromatin-associated retinoblastoma tumor suppressor complex. The Plant Cell. 22: 3331-47. PMID 20978220 DOI: 10.1105/tpc.110.076067  1
2010 Yoon YS, Lee MW, Ryu D, Kim JH, Ma H, Seo WY, Kim YN, Kim SS, Lee CH, Hunter T, Choi CS, Montminy MR, Koo SH. Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 17704-9. PMID 20876121 DOI: 10.1073/pnas.1012665107  1
2010 Liew CW, Sun H, Hunter T, Day CL. RING domain dimerization is essential for RNF4 function. The Biochemical Journal. 431: 23-9. PMID 20681948 DOI: 10.1042/BJ20100957  1
2010 Lu Z, Hunter T. Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitors. Cell Cycle (Georgetown, Tex.). 9: 2342-52. PMID 20519948 DOI: 10.4161/cc.9.12.11988  1
2010 López-Otín C, Hunter T. The regulatory crosstalk between kinases and proteases in cancer. Nature Reviews. Cancer. 10: 278-92. PMID 20300104 DOI: 10.1038/nrc2823  1
2010 Hunter T, Marais R. Genetic and cellular mechanisms of oncogenesis. Current Opinion in Genetics & Development. 20: 1-3. PMID 20116234 DOI: 10.1016/j.gde.2010.01.001  1
2010 Hunter T. Part II. Transmission: Effectors and Cytosolic Events Handbook of Cell Signaling, 2/E. 2: 385-389. DOI: 10.1016/B978-0-12-374145-5.00392-2  1
2010 Manning G, Hunter T. Eukaryotic kinomes. genomics and evolution of protein kinases Handbook of Cell Signaling, 2/E. 2: 393-397. DOI: 10.1016/B978-0-12-374145-5.00056-5  1
2009 You Z, Shi LZ, Zhu Q, Wu P, Zhang YW, Basilio A, Tonnu N, Verma IM, Berns MW, Hunter T. CtIP links DNA double-strand break sensing to resection. Molecular Cell. 36: 954-69. PMID 20064462 DOI: 10.1016/j.molcel.2009.12.002  1
2009 Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G, Morgan DO, Tsai LH, Wolgemuth DJ. Cyclin-dependent kinases: a family portrait. Nature Cell Biology. 11: 1275-6. PMID 19884882 DOI: 10.1038/ncb1109-1275  1
2009 Zhang YW, Brognard J, Coughlin C, You Z, Dolled-Filhart M, Aslanian A, Manning G, Abraham RT, Hunter T. The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Molecular Cell. 35: 442-53. PMID 19716789 DOI: 10.1016/j.molcel.2009.06.030  1
2009 Carrano AC, Liu Z, Dillin A, Hunter T. A conserved ubiquitination pathway determines longevity in response to diet restriction. Nature. 460: 396-9. PMID 19553937 DOI: 10.1038/nature08130  1
2009 Lu Z, Hunter T. Degradation of activated protein kinases by ubiquitination. Annual Review of Biochemistry. 78: 435-75. PMID 19489726 DOI: 10.1146/annurev.biochem.013008.092711  1
2009 Pearson GW, Hunter T. PI-3 kinase activity is necessary for ERK1/2-induced disruption of mammary epithelial architecture. Breast Cancer Research : Bcr. 11: R29. PMID 19457236 DOI: 10.1186/bcr2259  1
2009 Hunter T. Tyrosine phosphorylation: thirty years and counting. Current Opinion in Cell Biology. 21: 140-6. PMID 19269802 DOI: 10.1016/  1
2009 Copp J, Manning G, Hunter T. TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. Cancer Research. 69: 1821-7. PMID 19244117 DOI: 10.1158/0008-5472.CAN-08-3014  1
2009 Smith JJ, Putta S, Zhu W, Pao GM, Verma IM, Hunter T, Bryant SV, Gardiner DM, Harkins TT, Voss SR. Genic regions of a large salamander genome contain long introns and novel genes. Bmc Genomics. 10: 19. PMID 19144141 DOI: 10.1186/1471-2164-10-19  1
2009 Monaghan JR, Epp LG, Putta S, Page RB, Walker JA, Beachy CK, Zhu W, Pao GM, Verma IM, Hunter T, Bryant SV, Gardiner DM, Harkins TT, Voss SR. Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration. Bmc Biology. 7: 1. PMID 19144100 DOI: 10.1186/1741-7007-7-1  1
2008 Hunter T, Sun H. Crosstalk between the SUMO and ubiquitin pathways Ernst Schering Foundation Symposium Proceedings. 1-16. PMID 19202597  1
2008 Hunter T. Tony Hunter: kinase king. Interview by Ruth Williams. The Journal of Cell Biology. 181: 572-3. PMID 18490508 DOI: 10.1083/jcb.1814pi  1
2008 Hashimoto T, Yamauchi L, Hunter T, Kikkawa U, Kamada S. Possible involvement of caspase-7 in cell cycle progression at mitosis. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 13: 609-21. PMID 18459962 DOI: 10.1111/j.1365-2443.2008.01192.x  1
2008 Bishop JM, Hanahan D, Tlsty T, Hunter T, Lowe S, Varmus H, Dornbush KT, Waring JF, Jacks T, Gilmer T, Sherman M, Gerritsen W, Curran T, Doroshow J, Barrett JC, et al. The 20th Aspen Cancer Conference: Mechanisms of Toxicity, Carcinogenesis, Cancer Prevention, and Cancer Therapy 2005 Molecular Carcinogenesis. 47: 707-732. PMID 18286481 DOI: 10.1002/mc.20214  1
2008 Bailis JM, Luche DD, Hunter T, Forsburg SL. Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote s-phase genome stability. Molecular and Cellular Biology. 28: 1724-38. PMID 18180284 DOI: 10.1128/MCB.01717-07  1
2008 Ghosh S, Marquardt T, Thaler JP, Carter N, Andrews SE, Pfaff SL, Hunter T. Instructive role of aPKCzeta subcellular localization in the assembly of adherens junctions in neural progenitors. Proceedings of the National Academy of Sciences of the United States of America. 105: 335-40. PMID 18162555 DOI: 10.1073/pnas.0705713105  1
2008 Lu Z, Hunter T. MEKK1: Dual Function as a Protein Kinase and a Ubiquitin Protein Ligase Protein Degradation. 2: 79-87. DOI: 10.1002/9783527620210.ch4  1
2007 Pearson GW, Hunter T. Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells. The Journal of Cell Biology. 179: 1555-67. PMID 18166657 DOI: 10.1083/jcb.200706099  1
2007 Hunter T. The age of crosstalk: phosphorylation, ubiquitination, and beyond. Molecular Cell. 28: 730-8. PMID 18082598 DOI: 10.1016/j.molcel.2007.11.019  1
2007 You Z, Bailis JM, Johnson SA, Dilworth SM, Hunter T. Rapid activation of ATM on DNA flanking double-strand breaks. Nature Cell Biology. 9: 1311-8. PMID 17952060 DOI: 10.1038/ncb1651  1
2007 Sun H, Leverson JD, Hunter T. Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins. The Embo Journal. 26: 4102-12. PMID 17762864 DOI: 10.1038/sj.emboj.7601839  1
2007 Hunter T. Treatment for chronic myelogenous leukemia: the long road to imatinib. The Journal of Clinical Investigation. 117: 2036-43. PMID 17671637 DOI: 10.1172/JCI31691  1
2007 Zhang Y, Daum S, Wildemann D, Zhou XZ, Verdecia MA, Bowman ME, Lücke C, Hunter T, Lu KP, Fischer G, Noel JP. Structural basis for high-affinity peptide inhibition of human Pin1. Acs Chemical Biology. 2: 320-8. PMID 17518432 DOI: 10.1021/cb7000044  1
2007 Johnson SA, You Z, Hunter T. Monitoring ATM kinase activity in living cells. Dna Repair. 6: 1277-84. PMID 17428747 DOI: 10.1016/j.dnarep.2007.02.025  1
2007 Han EKH, Leverson JD, McGonigal T, Shah OJ, Woods KW, Hunter T, Giranda VL, Luo Y. Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition Oncogene. 26: 5655-5661. PMID 17334390 DOI: 10.1038/sj.onc.1210343  1
2007 Hunter T, Simon J. A not so brief history of the oncogene meeting and its cartoons Oncogene. 26: 1260-1267. PMID 17322910 DOI: 10.1038/sj.onc.1210262  1
2007 Bozulic L, Morin P, Hunter T, Hemmings BA. Meeting report: targeting the kinome--20 years of tyrosine kinase inhibitor research in Basel. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe8. PMID 17317657 DOI: 10.1126/stke.3742007pe8  1
2007 Fang D, Hawke D, Zheng Y, Xia Y, Meisenhelder J, Nika H, Mills GB, Kobayashi R, Hunter T, Lu Z. Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity. The Journal of Biological Chemistry. 282: 11221-9. PMID 17287208 DOI: 10.1074/jbc.M611871200  1
2007 Xia Y, Wang J, Liu TJ, Yung WK, Hunter T, Lu Z. c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis. Molecular Cell. 25: 219-32. PMID 17244530 DOI: 10.1016/j.molcel.2007.01.005  1
2007 Xia Y, Wang J, Xu S, Johnson GL, Hunter T, Lu Z. MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress. Molecular and Cellular Biology. 27: 510-7. PMID 17101801 DOI: 10.1128/MCB.01355-06  1
2006 Ghosh S, Tergaonkar V, Rothlin CV, Correa RG, Bottero V, Bist P, Verma IM, Hunter T. Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival. Cancer Cell. 10: 215-26. PMID 16959613 DOI: 10.1016/j.ccr.2006.08.007  1
2006 Shah OJ, Hunter T. Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis. Molecular and Cellular Biology. 26: 6425-34. PMID 16914728 DOI: 10.1128/MCB.01254-05  1
2006 Joazeiro CA, Anderson KC, Hunter T. Proteasome inhibitor drugs on the rise. Cancer Research. 66: 7840-2. PMID 16861477 DOI: 10.1158/0008-5472.CAN-06-2033  1
2006 Wolff S, Ma H, Burch D, Maciel GA, Hunter T, Dillin A. SMK-1, an essential regulator of DAF-16-mediated longevity. Cell. 124: 1039-53. PMID 16530049 DOI: 10.1016/j.cell.2005.12.042  1
2006 Petersen P, Chou DM, You Z, Hunter T, Walter JC, Walter G. Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint. Molecular and Cellular Biology. 26: 1997-2011. PMID 16479016 DOI: 10.1128/MCB.26.5.1997-2011.2006  1
2006 Wang Z, Qi C, Krones A, Woodring P, Zhu X, Reddy JK, Evans RM, Rosenfeld MG, Hunter T. Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance. Cell Metabolism. 3: 111-22. PMID 16459312 DOI: 10.1016/j.cmet.2006.01.002  1
2006 Zhang YW, Hunter T, Abraham RT. Turning the replication checkpoint on and off. Cell Cycle (Georgetown, Tex.). 5: 125-8. PMID 16357541  1
2006 Celis JE, Carter N, Simons K, Small J, Hunter T, Shotton D. Cell Biology, Four-Volume Set Cell Biology, Four-Volume Set. 1.  1
2005 Hunter T, Schulman H. CaMKII structure--an elegant design. Cell. 123: 765-7. PMID 16325572 DOI: 10.1016/j.cell.2005.11.017  1
2005 Kamada S, Kikkawa U, Tsujimoto Y, Hunter T. A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association. Molecular and Cellular Biology. 25: 9469-77. PMID 16227597 DOI: 10.1128/MCB.25.21.9469-9477.2005  1
2005 Huang HK, Bailis JM, Leverson JD, Gómez EB, Forsburg SL, Hunter T. Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation. Molecular and Cellular Biology. 25: 9000-15. PMID 16199877 DOI: 10.1128/MCB.25.20.9000-9015.2005  1
2005 Watanabe N, Arai H, Iwasaki J, Shiina M, Ogata K, Hunter T, Osada H. Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways. Proceedings of the National Academy of Sciences of the United States of America. 102: 11663-8. PMID 16085715 DOI: 10.1073/pnas.0500410102  1
2005 You Z, Chahwan C, Bailis J, Hunter T, Russell P. ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Molecular and Cellular Biology. 25: 5363-79. PMID 15964794 DOI: 10.1128/MCB.25.13.5363-5379.2005  1
2005 Wang X, Li X, Meisenhelder J, Hunter T, Yoshida S, Asami T, Chory J. Autoregulation and homodimerization are involved in the activation of the plant steroid receptor BRI1. Developmental Cell. 8: 855-65. PMID 15935775 DOI: 10.1016/j.devcel.2005.05.001  1
2005 Takagi Y, Masuda CA, Chang WH, Komori H, Wang D, Hunter T, Joazeiro CA, Kornberg RD. Ubiquitin ligase activity of TFIIH and the transcriptional response to DNA damage. Molecular Cell. 18: 237-43. PMID 15837426 DOI: 10.1016/j.molcel.2005.03.007  1
2005 Marquardt T, Shirasaki R, Ghosh S, Andrews SE, Carter N, Hunter T, Pfaff SL. Coexpressed EphA receptors and ephrin-A ligands mediate opposing actions on growth cone navigation from distinct membrane domains. Cell. 121: 127-39. PMID 15820684 DOI: 10.1016/j.cell.2005.01.020  1
2005 Johnson SA, Hunter T. Kinomics: methods for deciphering the kinome. Nature Methods. 2: 17-25. PMID 15789031 DOI: 10.1038/nmeth731  1
2005 Papin JA, Hunter T, Palsson BO, Subramaniam S. Reconstruction of cellular signalling networks and analysis of their properties. Nature Reviews. Molecular Cell Biology. 6: 99-111. PMID 15654321 DOI: 10.1038/nrm1570  1
2005 Woodring PJ, Hunter T, Wang JY. Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition. The Journal of Biological Chemistry. 280: 10318-25. PMID 15632178 DOI: 10.1074/jbc.M410658200  1
2005 Shah OJ, Hunter T. Tuberous sclerosis and insulin resistance. Unlikely bedfellows reveal a TORrid affair. Cell Cycle (Georgetown, Tex.). 4: 46-51. PMID 15611656  1
2005 Kamada S, Kikkawa U, Tsujimoto Y, Hunter T. Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s). The Journal of Biological Chemistry. 280: 857-60. PMID 15569692 DOI: 10.1074/jbc.C400538200  1
2004 York JD, Hunter T. Signal transduction. Unexpected mediators of protein phosphorylation. Science (New York, N.Y.). 306: 2053-5. PMID 15604398 DOI: 10.1126/science.1107225  1
2004 Grabbe C, Zervas CG, Hunter T, Brown NH, Palmer RH. Focal adhesion kinase is not required for integrin function or viability in Drosophila. Development (Cambridge, England). 131: 5795-805. PMID 15525665 DOI: 10.1242/dev.01462  1
2004 Shah OJ, Wang Z, Hunter T. Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Current Biology : Cb. 14: 1650-6. PMID 15380067 DOI: 10.1016/j.cub.2004.08.026  1
2004 Johnson SA, Hunter T. Phosphoproteomics finds its timing. Nature Biotechnology. 22: 1093-4. PMID 15340474 DOI: 10.1038/nbt0904-1093  1
2004 Caenepeel S, Charydczak G, Sudarsanam S, Hunter T, Manning G. The mouse kinome: discovery and comparative genomics of all mouse protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 101: 11707-12. PMID 15289607 DOI: 10.1073/pnas.0306880101  0.96
2004 Alonso A, Sasin J, Bottini N, Friedberg I, Osterman A, Godzik A, Hunter T, Dixon J, Mustelin T. Protein tyrosine phosphatases in the human genome Cell. 117: 699-711. PMID 15186772 DOI: 10.1016/j.cell.2004.05.018  1
2004 Woodring PJ, Meisenhelder J, Johnson SA, Zhou GL, Field J, Shah K, Bladt F, Pawson T, Niki M, Pandolfi PP, Wang JY, Hunter T. c-Abl phosphorylates Dok1 to promote filopodia during cell spreading. The Journal of Cell Biology. 165: 493-503. PMID 15148308 DOI: 10.1083/jcb.200312171  1
2004 Hunter T, Eckhart W. The discovery of tyrosine phosphorylation: it's all in the buffer! Cell. 116: S35-9, 1 p following. PMID 15055579  1
2003 Xia Y, Pao GM, Chen HW, Verma IM, Hunter T. Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein Journal of Biological Chemistry. 278: 5255-5263. PMID 12431996 DOI: 10.1074/jbc.M204591200  1
2002 Manning G, Plowman GD, Hunter T, Sudarsanam S. Evolution of protein kinase signaling from yeast to man. Trends in Biochemical Sciences. 27: 514-20. PMID 12368087  0.96
2002 Lu Z, Xu S, Joazeiro C, Cobb MH, Hunter T. The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2. Molecular Cell. 9: 945-56. PMID 12049732 DOI: 10.1016/S1097-2765(02)00519-1  1
2001 Tertoolen LG, Blanchetot C, Jiang G, Overvoorde J, Gadella TW, Hunter T, den Hertog J. Dimerization of receptor protein-tyrosine phosphatase alpha in living cells. Bmc Cell Biology. 2: 8. PMID 11401727 DOI: 10.1186/1471-2121-2-8  1
2000 Jiang G, den Hertog J, Hunter T. Receptor-like protein tyrosine phosphatase alpha homodimerizes on the cell surface. Molecular and Cellular Biology. 20: 5917-29. PMID 10913175 DOI: 10.1128/MCB.20.16.5917-5929.2000  1
2000 Pao GM, Janknecht R, Ruffner H, Hunter T, Verma IM. CBP/p300 interact with and function as transcriptional coactivators of BRCA1 Proceedings of the National Academy of Sciences of the United States of America. 97: 1020-1025. PMID 10655477 DOI: 10.1073/pnas.97.3.1020  1
1999 Jiang G, den Hertog J, Su J, Noel J, Sap J, Hunter T. Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alpha. Nature. 401: 606-10. PMID 10524630 DOI: 10.1038/44170  1
1996 Bilwes AM, den Hertog J, Hunter T, Noel JP. Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization. Nature. 382: 555-9. PMID 8700232 DOI: 10.1038/382555a0  1
1996 den Hertog J, Hunter T. Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains. The Embo Journal. 15: 3016-27. PMID 8670803  1
1994 Zhang SH, Broome MA, Lawton MA, Hunter T, Lamb CJ. atpk1, a novel ribosomal protein kinase gene from Arabidopsis. II. Functional and biochemical analysis of the encoded protein. The Journal of Biological Chemistry. 269: 17593-9. PMID 8021267  1
1994 den Hertog J, Tracy S, Hunter T. Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo. The Embo Journal. 13: 3020-32. PMID 7518772  1
1989 Nunn MF, Hunter T. The ets sequence is required for induction of erythroblastosis in chickens by avian retrovirus E26. Journal of Virology. 63: 398-402. PMID 2535740  1
1988 Weinmaster GA, Hunter T. Investigation of the role of P130gag-fps in transformation: generation and use of a temperature-sensitive mutant P130gag-fps. Journal of Virology. 62: 3849-54. PMID 2843679  1
1988 Weinmaster GA, Middlemas DS, Hunter T. A major site of tyrosine phosphorylation within the SH2 domain of Fujinami sarcoma virus P130gag-fps is not required for protein-tyrosine kinase activity or transforming potential. Journal of Virology. 62: 2016-25. PMID 2452898  1
1986 Cartwright CA, Kaplan PL, Cooper JA, Hunter T, Eckhart W. Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen. Molecular and Cellular Biology. 6: 1562-70. PMID 2431281  1
1986 Sefton BM, Hunter T. From c-src to v-src, or the case of the missing C terminus. Cancer Surveys. 5: 159-72. PMID 2430701  1
1986 Patschinsky T, Hunter T, Sefton BM. Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virus. Journal of Virology. 59: 73-81. PMID 2423705  1
1986 Cooper JA, Gould KL, Cartwright CA, Hunter T. Tyr527 is phosphorylated in pp60c-src: Implications for regulation Science. 231: 1431-1434. PMID 2420005  1
1985 Gould KL, Woodgett JR, Cooper JA, Buss JE, Shalloway D, Hunter T. Protein kinase C phosphorylates pp60src at a novel site Cell. 42: 849-857. PMID 2996780 DOI: 10.1016/0092-8674(85)90281-8  1
1984 Voronova AF, Buss JE, Patschinsky T, Hunter T, Sefton BM. Characterization of the protein apparently responsible for the elevated tyrosine protein kinase activity in LSTRA cells. Molecular and Cellular Biology. 4: 2705-13. PMID 6543243  1
1984 Cooper JA, Esch FS, Taylor SS, Hunter T. Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinase in vivo and in vitro Journal of Biological Chemistry. 259: 7835-7841. PMID 6330085  1
1984 Donoghue DJ, Anderson C, Hunter T, Kaplan PL. Transmission of the polyoma virus middle T gene as the oncogene of a murine retrovirus. Nature. 308: 748-50. PMID 6325917 DOI: 10.1038/308748a0  1
1984 Gould KL, Cooper JA, Hunter T. The 46,000-dalton tyrosine protein kinase substrate is widespread, whereas the 36,000-dalton substrate is only expressed at high levels in certain rodent tissues Journal of Cell Biology. 98: 487-497. PMID 6319429  1
1984 Cooper JA, Sefton BM, Hunter T. Diverse mitogenic agents induce the phosphorylation of two related 42,000-dalton proteins on tyrosine in quiescent chick cells. Molecular and Cellular Biology. 4: 30-7. PMID 6199661  1
1984 Sefton BM, Hunter T. Tyrosine protein kinases. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 18: 195-226. PMID 6093480  1
1983 Nigg EA, Cooper JA, Hunter T. Immunofluorescent localization of a 39,000-dalton substrate of tyrosine protein kinases to the cytoplasmic surface of the plasma membrane. The Journal of Cell Biology. 96: 1601-9. PMID 6304112 DOI: 10.1083/jcb.96.6.1601  0.36
1983 Donoghue DJ, Hunter T. Recombinational junctions of variants of Moloney murine sarcoma virus: generation and divergence of a mammalian transforming gene. Journal of Virology. 45: 607-17. PMID 6300424  1
1983 Sefton BM, Hunter T, Cooper JA. Some lymphoid cell lines transformed by Abelson murine leukemia virus lack a major 36,000-dalton tyrosine protein kinase substrate. Molecular and Cellular Biology. 3: 56-63. PMID 6298608  1
1983 Cooper JA, Sefton BM, Hunter T. Detection and quantification of phosphotyrosine in proteins. Methods in Enzymology. 99: 387-402. PMID 6196603 DOI: 10.1016/0076-6879(83)99075-4  1
1983 Cooper JA, Reiss NA, Schwartz RJ, Hunter T. Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus. Nature. 302: 218-23. PMID 6188054 DOI: 10.1038/302218a0  0.36
1982 Sefton BM, Hunter T, Nigg EA, Singer SJ, Walter G. Cytoskeletal targets for viral transforming proteins with tyrosine protein kinase activity. Cold Spring Harbor Symposia On Quantitative Biology. 46: 939-51. PMID 6809406  1
1982 Nigg EA, Sefton BM, Hunter T, Walter G, Singer SJ. Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide. Proceedings of the National Academy of Sciences of the United States of America. 79: 5322-6. PMID 6291037  1
1982 Adkins B, Hunter T, Beemon K. Expression of the PRC II avian sarcoma virus genome Journal of Virology. 41: 767-780. PMID 6284969  1
1982 Donoghue DJ, Hunter T. A generalized method of subcloning DNA fragments by restriction site reconstruction: application to sequencing the amino-terminal coding region of the transforming gene of Gazdar murine sarcoma virus. Nucleic Acids Research. 10: 2549-64. PMID 6281735 DOI: 10.1093/nar/10.8.2549  1
1982 Patschinsky T, Hunter T, Esch FS, Cooper JA, Sefton BM. Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 79: 973-7. PMID 6280176 DOI: 10.1073/pnas.79.4.973  1
1982 Donoghue DJ, Hunter T. Expression of transforming region of Moloney murine sarcoma virus in Escherichia coli as a fusion protein with small tumor antigen of polyoma virus. Proceedings of the National Academy of Sciences of the United States of America. 79: 800-4. PMID 6278495  1
1982 Adkins B, Hunter T, Sefton BM. The transforming proteins of PRCII virus and Rous sarcoma virus form a complex with the same two cellular phosphoproteins. Journal of Virology. 43: 448-55. PMID 6180178  1
1982 Cooper JA, Hunter T. Discrete primary locations of a tyrosine-protein kinase and of three proteins that contain phosphotyrosine in virally transformed chick fibroblasts. The Journal of Cell Biology. 94: 287-96. PMID 6179948 DOI: 10.1083/jcb.94.2.287  0.36
1982 Sefton BM, Patschinsky T, Berdot C, Hunter T, Elliott T. Phosphorylation and metabolism of the transforming protein of Rous sarcoma virus. Journal of Virology. 41: 813-20. PMID 6178840  1
1981 Adkins B, Hunter T. Identification of a packaged cellular mRNA in virions of Rous sarcoma virus Journal of Virology. 39: 471-480. PMID 6268836  1
1981 Sefton BM, Hunter T, Ball EH, Singer SJ. Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus. Cell. 24: 165-74. PMID 6263485 DOI: 10.1016/0092-8674(81)90512-2  1
1981 Sefton BM, Hunter T, Raschke WC. Evidence that the Abelson virus protein functions in vivo as a protein kinase that phosphorylates tyrosine. Proceedings of the National Academy of Sciences of the United States of America. 78: 1552-6. PMID 6262813  1
1981 Cooper JA, Hunter T. Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus. The Journal of Cell Biology. 91: 878-83. PMID 6173387 DOI: 10.1083/jcb.91.3.878  0.36
1981 Cooper JA, Hunter T. Changes in protein phosphorylation in Rous sarcoma virus-transformed chicken embryo cells. Molecular and Cellular Biology. 1: 165-78. PMID 6100962 DOI: 10.1128/mcb.1.2.165  0.36
1981 Cooper JA, Hunter T. Four different classes of retroviruses induce phosphorylation of tyrosines present in similar cellular proteins. Molecular and Cellular Biology. 1: 394-407. PMID 6086011 DOI: 10.1128/mcb.1.5.394  0.36
1980 Papkoff J, Hunter T, Beemon K. In vitro translation of virion RNA from Moloney murine sarcoma virus Virology. 101: 91-103. PMID 7355580 DOI: 10.1016/0042-6822(80)90486-9  1
1980 Hunter T, Sefton BM, Beemon K. Studies on the structure and function of the avian sarcoma virus transforming-gene product. Cold Spring Harbor Symposia On Quantitative Biology. 44: 931-41. PMID 6253224  1
1980 Sefton BM, Hunter T, Beemon K, Eckhart W. Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus. Cell. 20: 807-16. PMID 6251974  1
1980 Sefton BM, Hunter T, Beemon K. Relationship of polypeptide products of the transforming gene of Rous sarcoma virus and the homologous gene of vertebrates. Proceedings of the National Academy of Sciences of the United States of America. 77: 2059-63. PMID 6246520  1
1980 Hunter T, Sefton BM. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proceedings of the National Academy of Sciences of the United States of America. 77: 1311-5. PMID 6246487  1
1980 Sefton BM, Hunter T, Beemon K. Temperature-sensitive transformation by Rous sarcoma virus and temperature-sensitive protein kinase activity. Journal of Virology. 33: 220-9. PMID 6245228  1
1979 Sefton BM, Hunter T, Beemon K. Product of in vitro translation of the Rous sarcoma virus src gene has protein kinase activity. Journal of Virology. 30: 311-8. PMID 225522  1
1979 Beemon K, Hunter T, Sefton BM. Polymorphism of avian sarcoma virus src proteins. Journal of Virology. 30: 190-200. PMID 225515  1
1978 Sefton BM, Beemon K, Hunter T. Comparison of the expression of the src gene of Rous sarcoma virus in vitro and in vivo. Journal of Virology. 28: 957-71. PMID 215787  1
1978 Beemon K, Hunter T. Characterization of Rous sarcoma virus src gene products synthesized in vitro Journal of Virology. 28: 551-566. PMID 214578  1
1977 Beemon K, Hunter T. In vitro translation yields a possible Rous sarcoma virus src gene product Proceedings of the National Academy of Sciences of the United States of America. 74: 3302-3306. PMID 198780  1
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