Wylie Vale - Publications

Affiliations: 
Salk Institute for Biological Studies, La Jolla, CA, United States 
Area:
Neuroendocrinology

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Year Citation  Score
2019 Dautzenberg FM, Grigoriadis DE, Hauger RL, Risbrough VB, Steckler T, Vale WW, Valentino RJ. Corticotropin-releasing factor receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f19/2019.4  0.585
2013 Flandreau EI, Bourke CH, Ressler KJ, Vale WW, Nemeroff CB, Owens MJ. Escitalopram alters gene expression and HPA axis reactivity in rats following chronic overexpression of corticotropin-releasing factor from the central amygdala. Psychoneuroendocrinology. 38: 1349-61. PMID 23267723 DOI: 10.1016/J.Psyneuen.2012.11.020  0.802
2012 Neufeld-Cohen A, Kelly PA, Paul ED, Carter RN, Skinner E, Olverman HJ, Vaughan JM, Issler O, Kuperman Y, Lowry CA, Vale WW, Seckl JR, Chen A, Jamieson PM. Chronic activation of corticotropin-releasing factor type 2 receptors reveals a key role for 5-HT1A receptor responsiveness in mediating behavioral and serotonergic responses to stressful challenge. Biological Psychiatry. 72: 437-47. PMID 22704666 DOI: 10.1016/J.Biopsych.2012.05.005  0.478
2012 Wiater E, Vale W. Roles of activin family in pancreatic development and homeostasis. Molecular and Cellular Endocrinology. 359: 23-9. PMID 22406274 DOI: 10.1016/J.Mce.2012.02.015  0.73
2012 Bilezikjian LM, Justice NJ, Blackler AN, Wiater E, Vale WW. Cell-type specific modulation of pituitary cells by activin, inhibin and follistatin. Molecular and Cellular Endocrinology. 359: 43-52. PMID 22330643 DOI: 10.1016/J.Mce.2012.01.025  0.741
2012 Spike BT, Kelber JA, Kalathur M, Booker E, Lipianskaya J, Klemke R, Vale W, Wahl G, Gray PC. Abstract 3493: Soluble ALK4 extracellular domain antagonizes the cancer/stem cell phenotype caused by Nodal and Cripto signaling in mammary epithelia Cancer Research. 72: 3493-3493. DOI: 10.1158/1538-7445.Am2012-3493  0.718
2011 Bilezikjian LM, Vale WW. The Local Control of the Pituitary by Activin Signaling and Modulation. Open Neuroendocrinology Journal (Online). 4: 90-101. PMID 21927629 DOI: 10.2174/1876528901104010090  0.33
2011 Justice NJ, Blount AL, Pelosi E, Schlessinger D, Vale W, Bilezikjian LM. Impaired FSHbeta expression in the pituitaries of Foxl2 mutant animals. Molecular Endocrinology (Baltimore, Md.). 25: 1404-15. PMID 21700720 DOI: 10.1210/Me.2011-0093  0.38
2011 Jamieson PM, Cleasby ME, Kuperman Y, Morton NM, Kelly PA, Brownstein DG, Mustard KJ, Vaughan JM, Carter RN, Hahn CN, Hardie DG, Seckl JR, Chen A, Vale WW. Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet. Diabetologia. 54: 2392-403. PMID 21667214 DOI: 10.1007/S00125-011-2205-6  0.43
2011 Fekete EM, Zhao Y, Szücs A, Sabino V, Cottone P, Rivier J, Vale WW, Koob GF, Zorrilla EP. Systemic urocortin 2, but not urocortin 1 or stressin 1-A, suppresses feeding via CRF2 receptors without malaise and stress. British Journal of Pharmacology. 164: 1959-75. PMID 21627635 DOI: 10.1111/J.1476-5381.2011.01512.X  0.429
2011 Huising MO, Pilbrow AP, Matsumoto M, van der Meulen T, Park H, Vaughan JM, Lee S, Vale WW. Glucocorticoids differentially regulate the expression of CRFR1 and CRFR2α in MIN6 insulinoma cells and rodent islets. Endocrinology. 152: 138-50. PMID 21106875 DOI: 10.1210/en.2010-0791  0.502
2011 Kuperman Y, Issler O, Vaughan J, Bilezikjian L, Vale W, Chen A. Expression and regulation of corticotropin-releasing factor receptor type 2β in developing and mature mouse skeletal muscle. Molecular Endocrinology (Baltimore, Md.). 25: 157-69. PMID 21084379 DOI: 10.1210/Me.2010-0308  0.549
2010 Neufeld-Cohen A, Tsoory MM, Evans AK, Getselter D, Gil S, Lowry CA, Vale WW, Chen A. A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery. Proceedings of the National Academy of Sciences of the United States of America. 107: 19020-5. PMID 20937857 DOI: 10.1073/Pnas.1013761107  0.582
2010 Looyenga BD, Wiater E, Vale W, Hammer GD. Inhibin-A antagonizes TGFbeta2 signaling by down-regulating cell surface expression of the TGFbeta coreceptor betaglycan. Molecular Endocrinology (Baltimore, Md.). 24: 608-20. PMID 20160125 DOI: 10.1210/Me.2008-0374  0.74
2010 Huising MO, van der Meulen T, Vaughan JM, Matsumoto M, Donaldson CJ, Park H, Billestrup N, Vale WW. CRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 107: 912-7. PMID 20080775 DOI: 10.1073/pnas.0913610107  0.475
2010 Neufeld-Cohen A, Evans AK, Getselter D, Spyroglou A, Hill A, Gil S, Tsoory M, Beuschlein F, Lowry CA, Vale W, Chen A. Urocortin-1 and -2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits. Molecular Psychiatry. 15: 426-41, 339. PMID 19884890 DOI: 10.1038/Mp.2009.115  0.65
2010 Huang MM, Overstreet DH, Knapp DJ, Angel R, Wills TA, Navarro M, Rivier J, Vale W, Breese GR. Corticotropin-releasing factor (CRF) sensitization of ethanol withdrawal-induced anxiety-like behavior is brain site specific and mediated by CRF-1 receptors: relation to stress-induced sensitization. The Journal of Pharmacology and Experimental Therapeutics. 332: 298-307. PMID 19843974 DOI: 10.1124/Jpet.109.159186  0.332
2010 Neufeld-Cohen A, Evans AK, Getselter D, Spyroglou A, Hill A, Gil S, Tsoory M, Beuschlein F, Lowry CA, Vale W, Chen A. Urocortin-1 and-2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits Molecular Psychiatry. 15: 442. DOI: 10.1038/mp.2009.135  0.552
2009 Maji SK, Perrin MH, Sawaya MR, Jessberger S, Vadodaria K, Rissman RA, Singru PS, Nilsson KP, Simon R, Schubert D, Eisenberg D, Rivier J, Sawchenko P, Vale W, Riek R. Functional amyloids as natural storage of peptide hormones in pituitary secretory granules. Science (New York, N.Y.). 325: 328-32. PMID 19541956 DOI: 10.1126/Science.1173155  0.313
2009 Kelber JA, Panopoulos AD, Shani G, Booker EC, Belmonte JC, Vale WW, Gray PC. Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways. Oncogene. 28: 2324-36. PMID 19421146 DOI: 10.1038/Onc.2009.97  0.558
2009 Wiater E, Lewis KA, Donaldson C, Vaughan J, Bilezikjian L, Vale W. Endogenous betaglycan is essential for high-potency inhibin antagonism in gonadotropes. Molecular Endocrinology (Baltimore, Md.). 23: 1033-42. PMID 19372236 DOI: 10.1210/Me.2009-0021  0.772
2009 Sztainberg Y, Kuperman Y, Issler O, Gil S, Vaughan J, Rivier J, Vale W, Chen A. A novel corticotropin-releasing factor receptor splice variant exhibits dominant negative activity: a putative link to stress-induced heart disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2186-96. PMID 19246489 DOI: 10.1096/Fj.08-128066  0.547
2009 Ciarmela P, Wiater E, Smith SM, Vale W. Presence, actions, and regulation of myostatin in rat uterus and myometrial cells. Endocrinology. 150: 906-14. PMID 18845635 DOI: 10.1210/En.2008-0880  0.758
2009 Pattaroni C, Lucietto P, Goodman M, Yamamoto G, Vale W, Moroder L, Gazerro L, Göhring W, Schmied B, Wünsch E. Cyclic hexapeptides related to somatostatin. Synthesis and biological testing. International Journal of Peptide and Protein Research. 36: 401-417. PMID 1980489 DOI: 10.1111/J.1399-3011.1990.Tb01300.X  0.354
2008 Justice NJ, Yuan ZF, Sawchenko PE, Vale W. Type 1 corticotropin-releasing factor receptor expression reported in BAC transgenic mice: implications for reconciling ligand-receptor mismatch in the central corticotropin-releasing factor system. The Journal of Comparative Neurology. 511: 479-96. PMID 18853426 DOI: 10.1002/Cne.21848  0.4
2008 Hao Z, Huang Y, Cleman J, Jovin IS, Vale WW, Bale TL, Giordano FJ. Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 105: 3939-44. PMID 18308934 DOI: 10.1073/pnas.0712366105  0.485
2008 Ciarmela P, Wiater E, Vale W. Activin-A in myometrium: characterization of the actions on myometrial cells. Endocrinology. 149: 2506-16. PMID 18239071 DOI: 10.1210/En.2007-0692  0.742
2008 Kelber JA, Shani G, Booker EC, Vale WW, Gray PC. Cripto is a noncompetitive activin antagonist that forms analogous signaling complexes with activin and nodal. The Journal of Biological Chemistry. 283: 4490-500. PMID 18089557 DOI: 10.1074/Jbc.M704960200  0.539
2008 Korupolu RV, Muenster U, Read JD, Vale W, Fischer WH. Activin A/bone morphogenetic protein (BMP) chimeras exhibit BMP-like activity and antagonize activin and myostatin. The Journal of Biological Chemistry. 283: 3782-90. PMID 18056265 DOI: 10.1074/jbc.M704530200  0.357
2008 Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W, Gray PC. GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth. Molecular and Cellular Biology. 28: 666-77. PMID 17991893 DOI: 10.1128/Mcb.01716-07  0.577
2008 Gray PC, Shani G, Aung K, Kelber J, Vale W. Cripto binds transforming growth factor β (TGF-β) and inhibits TGF-β signaling (Molecular and Cellular Biology (2006) 26, 24, (9268-9278)) Molecular and Cellular Biology. 28: 7260. DOI: 10.1128/Mcb.01609-08  0.55
2008 Wiater E, Vale W. 4 Activins and Inhibins Cold Spring Harbor Monograph Archive. 50: 79-120. DOI: 10.1101/087969752.50.79  0.781
2007 Tabarin A, Diz-Chaves Y, Consoli D, Monsaingeon M, Bale TL, Culler MD, Datta R, Drago F, Vale WW, Koob GF, Zorrilla EP, Contarino A. Role of the corticotropin-releasing factor receptor type 2 in the control of food intake in mice: a meal pattern analysis. The European Journal of Neuroscience. 26: 2303-14. PMID 17953621 DOI: 10.1111/j.1460-9568.2007.05856.x  0.496
2007 Rissman RA, Lee KF, Vale W, Sawchenko PE. Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6552-62. PMID 17567816 DOI: 10.1523/Jneurosci.5173-06.2007  0.309
2007 Li C, Chen P, Vaughan J, Lee KF, Vale W. Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 104: 4206-11. PMID 17360501 DOI: 10.1073/Pnas.0611641104  0.31
2007 Rivier J, Gulyas J, Kunitake K, DiGruccio M, Cantle JP, Perrin MH, Donaldson C, Vaughan J, Million M, Gourcerol G, Adelson DW, Rivier C, Taché Y, Vale W. Stressin1-A, a potent corticotropin releasing factor receptor 1 (CRF1)-selective peptide agonist. Journal of Medicinal Chemistry. 50: 1668-74. PMID 17335188 DOI: 10.1021/jm0613875  0.596
2006 Florio P, Torres PB, Torricelli M, Toti P, Vale W, Petraglia F. Human endometrium expresses urocortin II and III messenger RNA and peptides. Fertility and Sterility. 86: 1766-70. PMID 17074339 DOI: 10.1016/j.fertnstert.2006.05.041  0.31
2006 Chen A, Brar B, Choi CS, Rousso D, Vaughan J, Kuperman Y, Kim SN, Donaldson C, Smith SM, Jamieson P, Li C, Nagy TR, Shulman GI, Lee KF, Vale W. Urocortin 2 modulates glucose utilization and insulin sensitivity in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 103: 16580-5. PMID 17050686 DOI: 10.1073/Pnas.0607337103  0.495
2006 Gray PC, Shani G, Aung K, Kelber J, Vale W. Cripto binds transforming growth factor beta (TGF-beta) and inhibits TGF-beta signaling. Molecular and Cellular Biology. 26: 9268-78. PMID 17030617 DOI: 10.1128/Mcb.01168-06  0.566
2006 Henry B, Vale W, Markou A. The effect of lateral septum corticotropin-releasing factor receptor 2 activation on anxiety is modulated by stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9142-52. PMID 16957071 DOI: 10.1523/Jneurosci.1494-06.2006  0.693
2006 Waser B, Rehmann R, Rivier J, Vale W, Reubi JC. CRF receptors in the rodent and human cardiovascular systems: species differences. Peptides. 27: 3029-38. PMID 16920225 DOI: 10.1016/j.peptides.2006.07.005  0.305
2006 Jamieson PM, Li C, Kukura C, Vaughan J, Vale W. Urocortin 3 modulates the neuroendocrine stress response and is regulated in rat amygdala and hypothalamus by stress and glucocorticoids. Endocrinology. 147: 4578-88. PMID 16809443 DOI: 10.1210/en.2006-0545  0.4
2006 Chen A, Zorrilla E, Smith S, Rousso D, Levy C, Vaughan J, Donaldson C, Roberts A, Lee KF, Vale W. Urocortin 2-deficient mice exhibit gender-specific alterations in circadian hypothalamus-pituitary-adrenal axis and depressive-like behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5500-10. PMID 16707802 DOI: 10.1523/Jneurosci.3955-05.2006  0.558
2006 Imperatore A, Florio P, Torres PB, Torricelli M, Galleri L, Toti P, Occhini R, Picciolini E, Vale W, Petraglia F. Urocortin 2 and urocortin 3 are expressed by the human placenta, deciduas, and fetal membranes. American Journal of Obstetrics and Gynecology. 195: 288-95. PMID 16626608 DOI: 10.1016/j.ajog.2005.12.048  0.341
2006 Wiater E, Harrison CA, Lewis KA, Gray PC, Vale WW. Identification of distinct inhibin and transforming growth factor beta-binding sites on betaglycan: functional separation of betaglycan co-receptor actions. The Journal of Biological Chemistry. 281: 17011-22. PMID 16621788 DOI: 10.1074/Jbc.M601459200  0.717
2006 Carlin KM, Vale WW, Bale TL. Vital functions of corticotropin-releasing factor (CRF) pathways in maintenance and regulation of energy homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 103: 3462-7. PMID 16492754 DOI: 10.1073/pnas.0511320103  0.524
2006 Smith SM, Vaughan JM, Donaldson CJ, Fernandez RE, Li C, Chen A, Vale WW. Cocaine- and amphetamine-regulated transcript is localized in pituitary lactotropes and is regulated during lactation. Endocrinology. 147: 1213-23. PMID 16339196 DOI: 10.1210/En.2005-1392  0.559
2005 Muenster U, Harrison CA, Donaldson C, Vale W, Fischer WH. An activin-A/C chimera exhibits activin and myostatin antagonistic properties. The Journal of Biological Chemistry. 280: 36626-32. PMID 16129674 DOI: 10.1074/jbc.M507236200  0.363
2005 Nemeroff CB, Vale WW. The neurobiology of depression: inroads to treatment and new drug discovery. The Journal of Clinical Psychiatry. 66: 5-13. PMID 16124836  0.334
2005 Chen AM, Perrin MH, Digruccio MR, Vaughan JM, Brar BK, Arias CM, Lewis KA, Rivier JE, Sawchenko PE, Vale WW. A soluble mouse brain splice variant of type 2alpha corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity. Proceedings of the National Academy of Sciences of the United States of America. 102: 2620-5. PMID 15701705 DOI: 10.1073/Pnas.0409583102  0.514
2005 Chen A, Perrin M, Brar B, Li C, Jamieson P, Digruccio M, Lewis K, Vale W. Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids. Molecular Endocrinology (Baltimore, Md.). 19: 441-58. PMID 15514029 DOI: 10.1210/Me.2004-0300  0.592
2004 Vale W, Wiater E, Gray P, Harrison C, Bilezikjian L, Choe S. Activins and inhibins and their signaling. Annals of the New York Academy of Sciences. 1038: 142-7. PMID 15838109 DOI: 10.1196/Annals.1315.023  0.745
2004 Florio P, Vale W, Petraglia F. Urocortins in human reproduction. Peptides. 25: 1751-7. PMID 15476942 DOI: 10.1016/j.peptides.2004.05.026  0.374
2004 Harrison CA, Wiater E, Gray PC, Greenwald J, Choe S, Vale W. Modulation of activin and BMP signaling. Molecular and Cellular Endocrinology. 225: 19-24. PMID 15451563 DOI: 10.1016/J.Mce.2004.02.008  0.734
2004 Weisinger RS, Blair-West JR, Burns P, Denton DA, Purcell B, Vale W, Rivier J, Weisinger HS, May CN. Cardiovascular effects of long-term central and peripheral administration of urocortin, corticotropin-releasing factor, and adrenocorticotropin in sheep. Endocrinology. 145: 5598-604. PMID 15319360 DOI: 10.1210/en.2004-0432  0.375
2004 Greenwald J, Vega ME, Allendorph GP, Fischer WH, Vale W, Choe S. A flexible activin explains the membrane-dependent cooperative assembly of TGF-beta family receptors. Molecular Cell. 15: 485-9. PMID 15304227 DOI: 10.1016/J.Molcel.2004.07.011  0.304
2004 Smith SM, Vaughan JM, Donaldson CJ, Rivier J, Li C, Chen A, Vale WW. Cocaine- and amphetamine-regulated transcript activates the hypothalamic-pituitary-adrenal axis through a corticotropin-releasing factor receptor-dependent mechanism. Endocrinology. 145: 5202-9. PMID 15271883 DOI: 10.1210/En.2004-0708  0.597
2004 Risbrough VB, Hauger RL, Roberts AL, Vale WW, Geyer MA. Corticotropin-releasing factor receptors CRF1 and CRF2 exert both additive and opposing influences on defensive startle behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6545-52. PMID 15269266 DOI: 10.1523/JNEUROSCI.5760-03.2004  0.577
2004 Harrison CA, Gray PC, Fischer WH, Donaldson C, Choe S, Vale W. An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors. The Journal of Biological Chemistry. 279: 28036-44. PMID 15123686 DOI: 10.1074/Jbc.M402782200  0.313
2004 Bale TL, Hoshijima M, Gu Y, Dalton N, Anderson KR, Lee KF, Rivier J, Chien KR, Vale WW, Peterson KL. The cardiovascular physiologic actions of urocortin II: acute effects in murine heart failure. Proceedings of the National Academy of Sciences of the United States of America. 101: 3697-702. PMID 14990799 DOI: 10.1073/Pnas.0307324101  0.508
2004 Bale TL, Vale WW. CRF and CRF receptors: role in stress responsivity and other behaviors. Annual Review of Pharmacology and Toxicology. 44: 525-57. PMID 14744257 DOI: 10.1146/annurev.pharmtox.44.101802.121410  0.527
2004 Chen A, Blount A, Vaughan J, Brar B, Vale W. Urocortin II gene is highly expressed in mouse skin and skeletal muscle tissues: localization, basal expression in corticotropin-releasing factor receptor (CRFR) 1- and CRFR2-null mice, and regulation by glucocorticoids. Endocrinology. 145: 2445-57. PMID 14736736 DOI: 10.1210/En.2003-1570  0.515
2004 Brar BK, Chen A, Perrin MH, Vale W. Specificity and regulation of extracellularly regulated kinase1/2 phosphorylation through corticotropin-releasing factor (CRF) receptors 1 and 2beta by the CRF/urocortin family of peptides. Endocrinology. 145: 1718-29. PMID 14670995 DOI: 10.1210/En.2003-1023  0.558
2004 Brar BK, Jonassen AK, Egorina EM, Chen A, Negro A, Perrin MH, Mjøs OD, Latchman DS, Lee KF, Vale W. Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart. Endocrinology. 145: 24-35; discussion 21. PMID 12970163 DOI: 10.1210/En.2003-0689  0.533
2003 Takabe K, Wang L, Leal AM, Macconell LA, Wiater E, Tomiya T, Ohno A, Verma IM, Vale W. Adenovirus-mediated overexpression of follistatin enlarges intact liver of adult rats. Hepatology (Baltimore, Md.). 38: 1107-15. PMID 14578849 DOI: 10.1053/Jhep.2003.50483  0.727
2003 Luckey A, Wang L, Jamieson PM, Basa NR, Million M, Czimmer J, Vale W, Taché Y. Corticotropin-releasing factor receptor 1-deficient mice do not develop postoperative gastric ileus. Gastroenterology. 125: 654-9. PMID 12949710 DOI: 10.1016/S0016-5085(03)01069-2  0.316
2003 Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Baban K, Affolter M, Vale WW, Izpisua Belmonte JC, Choe S. Structural basis of BMP signaling inhibition by Noggin, a novel twelve-membered cystine knot protein. The Journal of Bone and Joint Surgery. American Volume. 85: 52-8. PMID 12925610 DOI: 10.2106/00004623-200300003-00010  0.722
2003 Reubi JC, Waser B, Vale W, Rivier J. Expression of CRF1 and CRF2 receptors in human cancers. The Journal of Clinical Endocrinology and Metabolism. 88: 3312-20. PMID 12843181 DOI: 10.1210/jc.2002-021853  0.34
2003 Bale TL, Vale WW. Increased depression-like behaviors in corticotropin-releasing factor receptor-2-deficient mice: sexually dichotomous responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5295-301. PMID 12832554  0.49
2003 Li C, Chen P, Vaughan J, Blount A, Chen A, Jamieson PM, Rivier J, Smith MS, Vale W. Urocortin III is expressed in pancreatic beta-cells and stimulates insulin and glucagon secretion. Endocrinology. 144: 3216-24. PMID 12810578 DOI: 10.1210/En.2002-0087  0.583
2003 Chen A, Vaughan J, Vale WW. Glucocorticoids regulate the expression of the mouse urocortin II gene: a putative connection between the corticotropin-releasing factor receptor pathways. Molecular Endocrinology (Baltimore, Md.). 17: 1622-39. PMID 12764078 DOI: 10.1210/Me.2003-0054  0.503
2003 Bale TL, Anderson KR, Roberts AJ, Lee KF, Nagy TR, Vale WW. Corticotropin-releasing factor receptor-2-deficient mice display abnormal homeostatic responses to challenges of increased dietary fat and cold. Endocrinology. 144: 2580-7. PMID 12746321 DOI: 10.1210/En.2002-0091  0.516
2003 Adams BA, Tello JA, Erchegyi J, Warby C, Hong DJ, Akinsanya KO, Mackie GO, Vale W, Rivier JE, Sherwood NM. Six novel gonadotropin-releasing hormones are encoded as triplets on each of two genes in the protochordate, Ciona intestinalis. Endocrinology. 144: 1907-19. PMID 12697698 DOI: 10.1210/En.2002-0216  0.384
2003 Gray PC, Harrison CA, Vale W. Cripto forms a complex with activin and type II activin receptors and can block activin signaling. Proceedings of the National Academy of Sciences of the United States of America. 100: 5193-8. PMID 12682303 DOI: 10.1073/pnas.0531290100  0.33
2003 Greenwald J, Groppe J, Gray P, Wiater E, Kwiatkowski W, Vale W, Choe S. The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly. Molecular Cell. 11: 605-17. PMID 12667445 DOI: 10.1016/S1097-2765(03)00094-7  0.728
2003 Harrison CA, Gray PC, Koerber SC, Fischer W, Vale W. Identification of a functional binding site for activin on the type I receptor ALK4. The Journal of Biological Chemistry. 278: 21129-35. PMID 12665502 DOI: 10.1074/jbc.M302015200  0.321
2003 Hauger RL, Grigoriadis DE, Dallman MF, Plotsky PM, Vale WW, Dautzenberg FM. International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands. Pharmacological Reviews. 55: 21-6. PMID 12615952 DOI: 10.1124/pr.55.1.3  0.32
2003 Bale TL, Giordano FJ, Vale WW. A new role for corticotropin-releasing factor receptor-2: suppression of vascularization. Trends in Cardiovascular Medicine. 13: 68-71. PMID 12586442 DOI: 10.1016/S1050-1738(02)00214-1  0.55
2003 Fischer WH, Park M, Donaldson C, Wiater E, Vaughan J, Bilezikjian LM, Vale W. Residues in the C-terminal region of activin A determine specificity for follistatin and type II receptor binding. The Journal of Endocrinology. 176: 61-8. PMID 12525250 DOI: 10.1677/joe.0.1760061  0.31
2003 Wiater E, Vale W. Inhibin is an antagonist of bone morphogenetic protein signaling. The Journal of Biological Chemistry. 278: 7934-41. PMID 12493742 DOI: 10.1074/Jbc.M209710200  0.751
2002 Bale TL, Lee KF, Vale WW. The role of corticotropin-releasing factor receptors in stress and anxiety. Integrative and Comparative Biology. 42: 552-5. PMID 21708750 DOI: 10.1093/Icb/42.3.552  0.543
2002 Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Affolter M, Vale WW, Izpisua Belmonte JC, Choe S. Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. Nature. 420: 636-42. PMID 12478285 DOI: 10.1038/Nature01245  0.715
2002 Rivier J, Gulyas J, Kirby D, Low W, Perrin MH, Kunitake K, DiGruccio M, Vaughan J, Reubi JC, Waser B, Koerber SC, Martinez V, Wang L, Taché Y, Vale W. Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective peptide competitive antagonists. Journal of Medicinal Chemistry. 45: 4737-47. PMID 12361401 DOI: 10.1021/jm0202122  0.417
2002 Vetter DE, Li C, Zhao L, Contarino A, Liberman MC, Smith GW, Marchuk Y, Koob GF, Heinemann SF, Vale W, Lee KF. Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior. Nature Genetics. 31: 363-9. PMID 12091910 DOI: 10.1038/Ng914  0.31
2002 Valdez GR, Inoue K, Koob GF, Rivier J, Vale W, Zorrilla EP. Human urocortin II: mild locomotor suppressive and delayed anxiolytic-like effects of a novel corticotropin-releasing factor related peptide. Brain Research. 943: 142-50. PMID 12088848 DOI: 10.1016/S0006-8993(02)02707-5  0.332
2002 Bale TL, Giordano FJ, Hickey RP, Huang Y, Nath AK, Peterson KL, Vale WW, Lee KF. Corticotropin-releasing factor receptor 2 is a tonic suppressor of vascularization. Proceedings of the National Academy of Sciences of the United States of America. 99: 7734-9. PMID 12032352 DOI: 10.1073/Pnas.102187099  0.534
2002 Liu X, Nagarajan RP, Vale W, Chen Y. Phosphorylation regulation of the interaction between Smad7 and activin type I receptor. Febs Letters. 519: 93-8. PMID 12023024 DOI: 10.1016/S0014-5793(02)02718-7  0.334
2002 Martínez V, Wang L, Rivier JE, Vale W, Taché Y. Differential actions of peripheral corticotropin-releasing factor (CRF), urocortin II, and urocortin III on gastric emptying and colonic transit in mice: role of CRF receptor subtypes 1 and 2. The Journal of Pharmacology and Experimental Therapeutics. 301: 611-7. PMID 11961064 DOI: 10.1124/jpet.301.2.611  0.349
2002 Gray PC, Bilezikjian LM, Vale W. Antagonism of activin by inhibin and inhibin receptors: a functional role for betaglycan. Molecular and Cellular Endocrinology. 188: 254-60. PMID 11911962 DOI: 10.1016/S0303-7207(02)00037-0  0.341
2002 Spina MG, Merlo-Pich E, Akwa Y, Balducci C, Basso AM, Zorrilla EP, Britton KT, Rivier J, Vale WW, Koob GF. Time-dependent induction of anxiogenic-like effects after central infusion of urocortin or corticotropin-releasing factor in the rat. Psychopharmacology. 160: 113-21. PMID 11875628 DOI: 10.1007/s00213-001-0940-y  0.341
2002 Leal AM, Takabe K, Wang L, Donaldson CJ, MacConell LA, Bilezikjian LM, Verma IM, Vale W. Effect of adenovirus-mediated overexpression of follistatin and extracellular domain of activin receptor type II on gonadotropin secretion in vitro and in vivo. Endocrinology. 143: 964-9. PMID 11861519 DOI: 10.1210/Endo.143.3.8667  0.455
2002 Bale TL, Picetti R, Contarino A, Koob GF, Vale WW, Lee KF. Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 193-9. PMID 11756502  0.508
2002 Million M, Maillot C, Saunders P, Rivier J, Vale W, Taché Y. Human urocortin II, a new CRF-related peptide, displays selective CRF(2)-mediated action on gastric transit in rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 282: G34-40. PMID 11751155 DOI: 10.1152/ajpgi.00283.2001  0.356
2002 Bale TL, Picetti R, Contarino A, Koob GF, Vale WW, Lee K. Mice Deficient for Both Corticotropin-Releasing Factor Receptor 1 (CRFR1) and CRFR2 Have an Impaired Stress Response and Display Sexually Dichotomous Anxiety-Like Behavior The Journal of Neuroscience. 22: 193-199. DOI: 10.1523/Jneurosci.22-01-00193.2002  0.508
2001 Currie PJ, Coscina DV, Bishop C, Coiro CD, Koob GF, Rivier J, Vale W. Hypothalamic paraventricular nucleus injections of urocortin alter food intake and respiratory quotient. Brain Research. 916: 222-8. PMID 11597609 DOI: 10.1016/S0006-8993(01)02851-7  0.307
2001 Gray PC, Bilezikjian LM, Vale W. Antagonism of activin by inhibin and inhibin receptors: a functional role for betaglycan-glycan. Molecular and Cellular Endocrinology. 180: 47-53. PMID 11451571 DOI: 10.1016/S0303-7207(01)00515-9  0.341
2001 Lee S, Smith GW, Vale W, Lee KF, Rivier C. Mice that lack corticotropin-releasing factor (CRF) receptors type 1 show a blunted ACTH response to acute alcohol despite up-regulated constitutive hypothalamic CRF gene expression. Alcoholism, Clinical and Experimental Research. 25: 427-33. PMID 11290855 DOI: 10.1111/J.1530-0277.2001.Tb02231.X  0.537
2000 Chan RK, Vale WW, Sawchenko PE. Paradoxical activational effects of a corticotropin-releasing factor-binding protein "ligand inhibitor" in rat brain. Neuroscience. 101: 115-29. PMID 11068141 DOI: 10.1016/S0306-4522(00)00322-5  0.313
2000 Van Pett K, Viau V, Bittencourt JC, Chan RK, Li HY, Arias C, Prins GS, Perrin M, Vale W, Sawchenko PE. Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse. The Journal of Comparative Neurology. 428: 191-212. PMID 11064361 DOI: 10.1002/1096-9861(20001211)428:2<191::Aid-Cne1>3.0.Co;2-U  0.344
2000 Lewis KA, Gray PC, Blount AL, MacConell LA, Wiater E, Bilezikjian LM, Vale W. Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature. 404: 411-4. PMID 10746731 DOI: 10.1038/35006129  0.755
2000 Bale TL, Contarino A, Smith GW, Chan R, Gold LH, Sawchenko PE, Koob GF, Vale WW, Lee KF. Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress. Nature Genetics. 24: 410-4. PMID 10742108 DOI: 10.1038/74263  0.602
2000 Weisinger RS, Blair-West JR, Burns P, Denton DA, McKinley MJ, Purcell B, Vale W, Rivier J, Sunagawa K. The inhibitory effect of hormones associated with stress on Na appetite of sheep. Proceedings of the National Academy of Sciences of the United States of America. 97: 2922-7. PMID 10717005 DOI: 10.1073/pnas.040577997  0.355
2000 Spina MG, Basso AM, Zorrilla EP, Heyser CJ, Rivier J, Vale W, Merlo-Pich E, Koob GF. Behavioral effects of central administration of the novel CRF antagonist astressin in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 230-9. PMID 10693150 DOI: 10.1016/S0893-133X(99)00108-6  0.409
2000 Gray PC, Greenwald J, Blount AL, Kunitake KS, Donaldson CJ, Choe S, Vale W. Identification of a binding site on the type II activin receptor for activin and inhibin. The Journal of Biological Chemistry. 275: 3206-12. PMID 10652306 DOI: 10.1074/Jbc.275.5.3206  0.324
2000 Wang L, Martínez V, Vale W, Taché Y. Fos induction in selective hypothalamic neuroendocrine and medullary nuclei by intravenous injection of urocortin and corticotropin-releasing factor in rats. Brain Research. 855: 47-57. PMID 10650129 DOI: 10.1016/S0006-8993(99)02200-3  0.359
1999 Contarino A, Dellu F, Koob GF, Smith GW, Lee KF, Vale W, Gold LH. Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 1. Brain Research. 835: 1-9. PMID 10448190 DOI: 10.1016/S0006-8993(98)01158-5  0.309
1999 Rivier JE, Kirby DA, Lahrichi SL, Corrigan A, Vale WW, Rivier CL. Constrained corticotropin releasing factor antagonists (astressin analogues) with long duration of action in the rat. Journal of Medicinal Chemistry. 42: 3175-82. PMID 10447963 DOI: 10.1021/jm9902133  0.53
1999 Basso AM, Spina M, Rivier J, Vale W, Koob GF. Corticotropin-releasing factor antagonist attenuates the "anxiogenic-like" effect in the defensive burying paradigm but not in the elevated plus-maze following chronic cocaine in rats. Psychopharmacology. 145: 21-30. PMID 10445369 DOI: 10.1007/s002130051028  0.334
1999 Petraglia F, Florio P, Benedetto C, Marozio L, Di Blasio AM, Ticconi C, Piccione E, Luisi S, Genazzani AR, Vale W. Urocortin stimulates placental adrenocorticotropin and prostaglandin release and myometrial contractility in vitro. The Journal of Clinical Endocrinology and Metabolism. 84: 1420-3. PMID 10199789 DOI: 10.1210/jcem.84.4.5585  0.335
1999 Cervini L, Theobald P, Corrigan A, Craig AG, Rivier C, Vale W, Rivier J. Corticotropin releasing factor (CRF) agonists with reduced amide bonds and Ser7 substitutions. Journal of Medicinal Chemistry. 42: 761-8. PMID 10052982 DOI: 10.1021/jm980607e  0.469
1999 Turnbull AV, Smith GW, Lee S, Vale WW, Lee KF, Rivier C. CRF type I receptor-deficient mice exhibit a pronounced pituitary-adrenal response to local inflammation. Endocrinology. 140: 1013-7. PMID 9927337 DOI: 10.1210/endo.140.2.6675  0.485
1999 Lebrun JJ, Takabe K, Chen Y, Vale W. Roles of pathway-specific and inhibitory Smads in activin receptor signaling. Molecular Endocrinology (Baltimore, Md.). 13: 15-23. PMID 9892009 DOI: 10.1210/mend.13.1.0218  0.328
1999 Turnbull AV, Vaughan J, Rivier JE, Vale WW, Rivier C. Urocortin is not a significant regulator of intermittent electrofootshock-induced adrenocorticotropin secretion in the intact male rat. Endocrinology. 140: 71-8. PMID 9886809 DOI: 10.1210/endo.140.1.6419  0.58
1998 Lovejoy DA, Hewett-Emmett D, Porter CA, Cepoi D, Sheffield A, Vale WW, Tashian RE. Evolutionarily conserved, "acatalytic" carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3. Genomics. 54: 484-93. PMID 9878252 DOI: 10.1006/Geno.1998.5585  0.541
1998 Greenwald J, Le V, Corrigan A, Fischer W, Komives E, Vale W, Choe S. Characterization of the extracellular ligand-binding domain of the type II activin receptor. Biochemistry. 37: 16711-8. PMID 9843440 DOI: 10.1021/Bi981939O  0.363
1998 Rivier J, Gulyas J, Corrigan A, Martinez V, Craig AG, Taché Y, Vale W, Rivier C. Astressin analogues (corticotropin-releasing factor antagonists) with extended duration of action in the rat. Journal of Medicinal Chemistry. 41: 5012-9. PMID 9836619 DOI: 10.1021/jm980426c  0.556
1998 Koerber SC, Gulyas J, Lahrichi SL, Corrigan A, Craig AG, Rivier C, Vale W, Rivier J. Constrained corticotropin-releasing factor (CRF) agonists and antagonists with i-(i+3) Glu-Xaa-DXbb-Lys bridges. Journal of Medicinal Chemistry. 41: 5002-11. PMID 9836618 DOI: 10.1021/jm980350k  0.461
1998 Lovejoy DA, Aubry JM, Turnbull A, Sutton S, Potter E, Yehling J, Rivier C, Vale WW. Ectopic expression of the CRF-binding protein: minor impact on HPA axis regulation but induction of sexually dimorphic weight gain. Journal of Neuroendocrinology. 10: 483-91. PMID 9700675 DOI: 10.1046/j.1365-2826.1998.00206.x  0.696
1998 Smith GW, Aubry JM, Dellu F, Contarino A, Bilezikjian LM, Gold LH, Chen R, Marchuk Y, Hauser C, Bentley CA, Sawchenko PE, Koob GF, Vale W, Lee KF. Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development. Neuron. 20: 1093-102. PMID 9655498 DOI: 10.1016/S0896-6273(00)80491-2  0.404
1998 Rivier J, Lahrichi SL, Gulyas J, Erchegyi J, Koerber SC, Craig AG, Corrigan A, Rivier C, Vale W. Minimal-size, constrained corticotropin-releasing factor agonists with i-(i+3) Glu-Lys and Lys-Glu bridges. Journal of Medicinal Chemistry. 41: 2614-20. PMID 9651165 DOI: 10.1021/jm980164e  0.487
1998 Bilezikjian LM, Turnbull AV, Corrigan AZ, Blount AL, Rivier CL, Vale WW. Interleukin-1beta regulates pituitary follistatin and inhibin/activin betaB mRNA levels and attenuates FSH secretion in response to activin-A. Endocrinology. 139: 3361-4. PMID 9645713 DOI: 10.1210/endo.139.7.6190  0.485
1998 Petraglia F, Florio P, Luisi S, Gallo R, Gadducci A, Viganò P, Di Blasio AM, Genazzani AR, Vale W. Expression and secretion of inhibin and activin in normal and neoplastic uterine tissues. High levels of serum activin A in women with endometrial and cervical carcinoma. The Journal of Clinical Endocrinology and Metabolism. 83: 1194-200. PMID 9543140 DOI: 10.1210/jcem.83.4.4689  0.318
1997 Chen Y, Bhushan A, Vale W. Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 12938-43. PMID 9371779 DOI: 10.1073/Pnas.94.24.12938  0.312
1997 Miranda A, Lahrichi SL, Gulyas J, Koerber SC, Craig AG, Corrigan A, Rivier C, Vale W, Rivier J. Constrained corticotropin-releasing factor antagonists with i-(i + 3) Glu-Lys bridges. Journal of Medicinal Chemistry. 40: 3651-8. PMID 9357532 DOI: 10.1021/jm970311t  0.609
1997 Poliak S, Mor F, Conlon P, Wong T, Ling N, Rivier J, Vale W, Steinman L. Stress and autoimmunity: the neuropeptides corticotropin-releasing factor and urocortin suppress encephalomyelitis via effects on both the hypothalamic-pituitary-adrenal axis and the immune system. Journal of Immunology (Baltimore, Md. : 1950). 158: 5751-6. PMID 9190925  0.314
1997 Aubry JM, Turnbull AV, Pozzoli G, Rivier C, Vale W. Endotoxin decreases corticotropin-releasing factor receptor 1 messenger ribonucleic acid levels in the rat pituitary. Endocrinology. 138: 1621-6. PMID 9075723 DOI: 10.1210/endo.138.4.5050  0.575
1997 Boehme SA, Gaur A, Crowe PD, Liu XJ, Tamraz S, Wong T, Pahuja A, Ling N, Vale W, De Souza EB, Conlon PJ. Immunosuppressive phenotype of corticotropin-releasing factor transgenic mice is reversed by adrenalectomy. Cellular Immunology. 176: 103-12. PMID 9073382 DOI: 10.1006/cimm.1997.1080  0.367
1997 Maecker H, Desai A, Dash R, Rivier J, Vale W, Sapolsky R. Astressin, a novel and potent CRF antagonist, is neuroprotective in the hippocampus when administered after a seizure. Brain Research. 744: 166-70. PMID 9030428 DOI: 10.1016/S0006-8993(96)01207-3  0.545
1997 Vale W, Vaughan J, Perrin M. Corticotropin-Releasing Factor (CRF) Family of Ligands and Their Receptors Endocrinologist. 7. DOI: 10.1097/00019616-199707011-00002  0.439
1996 Rivier J, Jiang GC, Lahrichi SL, Porter J, Koerber SC, Rizo J, Corrigan A, Gierasch L, Hagler A, Vale W, Rivier C. Dose relationship between GnRH antagonists and pituitary suppression. Human Reproduction (Oxford, England). 11: 133-47. PMID 9147108 DOI: 10.1093/Humrep/11.Suppl_3.133  0.589
1996 Heinrichs SC, Stenzel-Poore MP, Gold LH, Battenberg E, Bloom FE, Koob GF, Vale WW, Pich EM. Learning impairment in transgenic mice with central overexpression of corticotropin-releasing factor. Neuroscience. 74: 303-11. PMID 8865183 DOI: 10.1016/0306-4522(96)00140-6  0.56
1996 Petraglia F, Florio P, Gallo R, Simoncini T, Saviozzi M, Di Blasio AM, Vaughan J, Vale W. Human placenta and fetal membranes express human urocortin mRNA and peptide. The Journal of Clinical Endocrinology and Metabolism. 81: 3807-10. PMID 8855842 DOI: 10.1210/Jcem.81.10.8855842  0.311
1996 Roberts VJ, Barth SL, Meunier H, Vale W. Hybridization histochemical and immunohistochemical localization of inhibin/activin subunits and messenger ribonucleic acids in the rat brain. The Journal of Comparative Neurology. 364: 473-493. PMID 8820878 DOI: 10.1002/(SICI)1096-9861(19960115)364:3<473::AID-CNE7>3.0.CO;2-1  0.333
1996 Turnbull AV, Vale W, Rivier C. Urocortin, a corticotropin-releasing factor-related mammalian peptide, inhibits edema due to thermal injury in rats. European Journal of Pharmacology. 303: 213-6. PMID 8813571 DOI: 10.1016/0014-2999(96)00141-0  0.611
1996 Imaki T, Naruse M, Harada S, Chikada N, Imaki J, Onodera H, Demura H, Vale W. Corticotropin-releasing factor up-regulates its own receptor mRNA in the paraventricular nucleus of the hypothalamus. Brain Research. Molecular Brain Research. 38: 166-70. PMID 8737681 DOI: 10.1016/0169-328X(96)00011-3  0.4
1996 Spina M, Merlo-Pich E, Chan RK, Basso AM, Rivier J, Vale W, Koob GF. Appetite-suppressing effects of urocortin, a CRF-related neuropeptide. Science (New York, N.Y.). 273: 1561-4. PMID 8703220 DOI: 10.1126/science.273.5281.1561  0.408
1996 Donaldson CJ, Sutton SW, Perrin MH, Corrigan AZ, Lewis KA, Rivier JE, Vaughan JM, Vale WW. Cloning and characterization of human urocortin. Endocrinology. 137: 2167-70. PMID 8612563 DOI: 10.1210/endo.137.5.8612563  0.305
1995 Behan DP, De Souza EB, Lowry PJ, Potter E, Sawchenko P, Vale WW. Corticotropin releasing factor (CRF) binding protein: a novel regulator of CRF and related peptides. Frontiers in Neuroendocrinology. 16: 362-82. PMID 8557170 DOI: 10.1006/Frne.1995.1013  0.305
1995 Gaddy-Kurten D, Tsuchida K, Vale W. Activins and the receptor serine kinase superfamily. Recent Progress in Hormone Research. 50: 109-29. PMID 7740154 DOI: 10.1016/B978-0-12-571150-0.50010-X  0.36
1995 Perrin M, Donaldson C, Chen R, Blount A, Berggren T, Bilezikjian L, Sawchenko P, Vale W. Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart. Proceedings of the National Academy of Sciences of the United States of America. 92: 2969-73. PMID 7708757 DOI: 10.1073/Pnas.92.7.2969  0.413
1995 Rivier JE, Jiang G, Porter J, Hoeger CA, Craig AG, Corrigan A, Vale W, Rivier CL. Gonadotropin-releasing hormone antagonists: novel members of the azaline B family. Journal of Medicinal Chemistry. 38: 2649-62. PMID 7629804 DOI: 10.1021/Jm00014A017  0.594
1995 Tsuchida K, Vaughan JM, Wiater E, Gaddy-Kurten D, Vale WW. Inactivation of activin-dependent transcription by kinase-deficient activin receptors. Endocrinology. 136: 5493-503. PMID 7588300 DOI: 10.1210/Endo.136.12.7588300  0.72
1995 Petraglia F, Benedetto C, Florio P, D'Ambrogio G, Genazzani AD, Marozio L, Vale W. Effect of corticotropin-releasing factor-binding protein on prostaglandin release from cultured maternal decidua and on contractile activity of human myometrium in vitro. The Journal of Clinical Endocrinology and Metabolism. 80: 3073-6. PMID 7559899 DOI: 10.1210/jcem.80.10.7559899  0.414
1995 Gulyas J, Rivier C, Perrin M, Koerber SC, Sutton S, Corrigan A, Lahrichi SL, Craig AG, Vale W, Rivier J. Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor. Proceedings of the National Academy of Sciences of the United States of America. 92: 10575-9. PMID 7479843 DOI: 10.1073/pnas.92.23.10575  0.579
1994 Miranda A, Koerber SC, Gulyas J, Lahrichi SL, Craig AG, Corrigan A, Hagler A, Rivier C, Vale W, Rivier J. Conformationally restricted competitive antagonists of human/rat corticotropin-releasing factor. Journal of Medicinal Chemistry. 37: 1450-9. PMID 8182703  0.525
1994 Stenzel-Poore MP, Heinrichs SC, Rivest S, Koob GF, Vale WW. Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 2579-84. PMID 8182429 DOI: 10.1523/Jneurosci.14-05-02579.1994  0.629
1994 Potter E, Sutton S, Donaldson C, Chen R, Perrin M, Lewis K, Sawchenko PE, Vale W. Distribution of corticotropin-releasing factor receptor mRNA expression in the rat brain and pituitary. Proceedings of the National Academy of Sciences of the United States of America. 91: 8777-81. PMID 8090722 DOI: 10.1073/Pnas.91.19.8777  0.396
1994 Parkes D, Kasckow J, Vale W. Carbon monoxide modulates secretion of corticotropin-releasing factor from rat hypothalamic cell cultures. Brain Research. 646: 315-8. PMID 8069681 DOI: 10.1016/0006-8993(94)90097-3  0.444
1994 Kasckow JW, Parkes DG, Owens MJ, Stipetic MD, Han JH, Nemeroff CB, Vale WW. The BE (2)-M17 neuroblastoma cell line synthesizes and secretes corticotropin-releasing factor. Brain Research. 654: 159-62. PMID 7982090 DOI: 10.1016/0006-8993(94)91583-0  0.602
1993 Pich EM, Koob GF, Heilig M, Menzaghi F, Vale W, Weiss F. Corticotropin-releasing factor release from the mediobasal hypothalamus of the rat as measured by microdialysis. Neuroscience. 55: 695-707. PMID 8413932 DOI: 10.1016/0306-4522(93)90435-I  0.411
1993 Hernandez JF, Kornreich W, Rivier C, Miranda A, Yamamoto G, Andrews J, Taché Y, Vale W, Rivier J. Synthesis and relative potencies of new constrained CRF antagonists. Journal of Medicinal Chemistry. 36: 2860-7. PMID 8411001 DOI: 10.1021/Jm00072A004  0.499
1993 Rivier J, Rivier C, Galyean R, Miranda A, Miller C, Craig AG, Yamamoto G, Brown M, Vale W. Single point D-substituted corticotropin-releasing factor analogues: effects on potency and physicochemical characteristics. Journal of Medicinal Chemistry. 36: 2851-9. PMID 8411000  0.519
1993 Petraglia F, Potter E, Cameron VA, Sutton S, Behan DP, Woods RJ, Sawchenko PE, Lowry PJ, Vale W. Corticotropin-releasing factor-binding protein is produced by human placenta and intrauterine tissues. The Journal of Clinical Endocrinology and Metabolism. 77: 919-24. PMID 8408466 DOI: 10.1210/Jcem.77.4.8408466  0.359
1993 Parkes DG, Yamamoto GY, Vaughan JM, Vale WW. Characterization and regulation of corticotropin-releasing factor in the human hepatoma NPLC-KC cell line. Neuroendocrinology. 57: 663-9. PMID 8396219  0.326
1993 Stenzel-Poore M, Vale WW, Rivier C. Relationship between antigen-induced immune stimulation and activation of the hypothalamic-pituitary-adrenal axis in the rat. Endocrinology. 132: 1313-8. PMID 8382598 DOI: 10.1210/endo.132.3.8382598  0.682
1993 Petraglia F, Anceschi MM, Calzá L, Garuti GC, Fusaro P, Giardino L, Genazzani AR, Vale W. Inhibin and activin in human fetal membranes: evidence for a local effect on prostaglandin release. The Journal of Clinical Endocrinology and Metabolism. 77: 542-8. PMID 8345060 DOI: 10.1210/jcem.77.2.8345060  0.337
1993 Parkes D, Rivest S, Lee S, Rivier C, Vale W. Corticotropin-releasing factor activates c-fos, NGFI-B, and corticotropin-releasing factor gene expression within the paraventricular nucleus of the rat hypothalamus. Molecular Endocrinology (Baltimore, Md.). 7: 1357-67. PMID 8264665 DOI: 10.1210/mend.7.10.8264665  0.559
1993 Imaki T, Vale W. Chlordiazepoxide attenuates stress-induced accumulation of corticotropin-releasing factor mRNA in the paraventricular nucleus. Brain Research. 623: 223-8. PMID 8221103 DOI: 10.1016/0006-8993(93)91431-Q  0.375
1993 Chen R, Lewis KA, Perrin MH, Vale WW. Expression cloning of a human corticotropin-releasing-factor receptor. Proceedings of the National Academy of Sciences of the United States of America. 90: 8967-71. PMID 7692441  0.355
1992 Knollema S, Brown ER, Vale W, Sawchenko PE. Novel hypothalamic and preoptic sites of prepro-melanin-concentrating hormone messenger ribonucleic Acid and Peptide expression in lactating rats. Journal of Neuroendocrinology. 4: 709-17. PMID 21554658 DOI: 10.1111/j.1365-2826.1992.tb00222.x  0.363
1992 Press M, Caprio S, Tamborlane WV, Bhushan R, Thorner M, Vale W, Rivier J, Sherwin RS. Pituitary response to growth hormone-releasing hormone in IDDM. Abnormal responses to insulin and hyperglycemia. Diabetes. 41: 17-21. PMID 1727733 DOI: 10.2337/Diab.41.1.17  0.337
1992 Bilezikjian LM, Blount AL, Campen CA, Gonzalez-Manchon C, Vale W. Activin-A inhibits proopiomelanocortin messenger RNA accumulation and adrenocorticotropin secretion of AtT20 cells. Molecular Endocrinology (Baltimore, Md.). 5: 1389-95. PMID 1663577 DOI: 10.1210/MEND-5-10-1389  0.408
1992 Risold PY, Fellmann D, Rivier J, Vale W, Bugnon C. Immunoreactivities for antisera to three putative neuropeptides of the rat melanin-concentrating hormone precursor are coexpressed in neurons of the rat lateral dorsal hypothalamus. Neuroscience Letters. 136: 145-9. PMID 1641182 DOI: 10.1016/0304-3940(92)90035-6  0.362
1992 Stenzel-Poore MP, Cameron VA, Vaughan J, Sawchenko PE, Vale W. Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice. Endocrinology. 130: 3378-86. PMID 1597149 DOI: 10.1210/Endo.130.6.1597149  0.658
1992 Petraglia F, Woodruff TK, Botticelli G, Botticelli A, Genazzani AR, Mayo KE, Vale W. Gonadotropin-releasing hormone, inbibin, and activin in human placenta: Evidence for a common cellular localization Journal of Clinical Endocrinology and Metabolism. 74: 1184-1188. PMID 1569165 DOI: 10.1210/Jcem.74.5.1569165  0.4
1992 Sawchenko PE, Arias C, Krasnov I, Grindeland RE, Vale W. Effects of spaceflight on hypothalamic peptide systems controlling pituitary growth hormone dynamics. Journal of Applied Physiology (Bethesda, Md. : 1985). 73: 158S-165S. PMID 1526945 DOI: 10.1152/Jappl.1992.73.2.S158  0.409
1992 Bittencourt JC, Presse F, Arias C, Peto C, Vaughan J, Nahon JL, Vale W, Sawchenko PE. The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization. The Journal of Comparative Neurology. 319: 218-45. PMID 1522246 DOI: 10.1002/Cne.903190204  0.369
1992 Imaki T, Vale W, Sawchenko PE. Regulation of corticotropin-releasing factor mRNA in neuroendocrine and autonomic neurons by osmotic stimulation and volume loading. Neuroendocrinology. 56: 633-40. PMID 1488095 DOI: 10.1159/000126286  0.379
1992 Vaughan JM, Rivier J, Spiess J, Peng C, Chang JP, Peter RE, Vale W. Isolation and characterization of hypothalamic growth-hormone releasing factor from common carp, Cyprinus carpio. Neuroendocrinology. 56: 539-49. PMID 1475012 DOI: 10.1159/000126272  0.656
1992 Stenzel-Poore MP, Heldwein KA, Stenzel P, Lee S, Vale WW. Characterization of the genomic corticotropin-releasing factor (CRF) gene from Xenopus laevis: two members of the CRF family exist in amphibians. Molecular Endocrinology (Baltimore, Md.). 6: 1716-24. PMID 1448118 DOI: 10.1210/mend.6.10.1448118  0.638
1992 Rivier C, Rivest S, Vale W. Alcohol-induced inhibition of LH secretion in intact and gonadectomized male and female rats: possible mechanisms. Alcoholism, Clinical and Experimental Research. 16: 935-41. PMID 1443432 DOI: 10.1111/j.1530-0277.1992.tb01896.x  0.561
1992 Roberts VJ, Peto CA, Vale W, Sawchenko PE. Inhibin/activin subunits are costored with FSH and LH in secretory granules of the rat anterior pituitary gland. Neuroendocrinology. 56: 214-24. PMID 1407376 DOI: 10.1159/000126231  0.355
1992 Kolp LA, Pavlou SN, Urban RJ, Rivier JC, Vale WW, Veldhuis JD. Abrogation by a potent gonadotropin-releasing hormone antagonist of the estrogen/progesterone-stimulated surge-like release of luteinizing hormone and follicle-stimulating hormone in postmenopausal women. The Journal of Clinical Endocrinology and Metabolism. 75: 993-7. PMID 1400893 DOI: 10.1210/jcem.75.4.1400893  0.34
1992 Voglmayr JK, Jolley D, Vale W, Willoughby D, Moser A, So CK, Chen CL, Bardin CW. Effects of follicle-stimulating hormone on inhibin release by different testicular compartments in the adult ram. Biology of Reproduction. 47: 573-581. PMID 1391344 DOI: 10.1095/Biolreprod47.4.573  0.35
1992 Parkes D, Vale W. Secretion of melanin-concentrating hormone and neuropeptide-EI from cultured rat hypothalamic cells. Endocrinology. 131: 1826-31. PMID 1327720 DOI: 10.1210/endo.131.4.1327720  0.417
1992 Jezová D, Bartanusz V, Westergren I, Johansson BB, Rivier J, Vale W, Rivier C. Rat melanin-concentrating hormone stimulates adrenocorticotropin secretion: evidence for a site of action in brain regions protected by the blood-brain barrier. Endocrinology. 130: 1024-9. PMID 1310274 DOI: 10.1210/endo.130.2.1310274  0.603
1992 Dahl KD, Campen CA, McGuinness DM, Vale W. Differential regulation in the release of bioactive versus immunoactive gonadotropins from cultured rat pituitary cells by inhibin and androgens. Journal of Andrology. 13: 526-33. PMID 1293132 DOI: 10.1002/J.1939-4640.1992.Tb00348.X  0.458
1992 Swerdloff RS, Tom LkS, Salameh W, Steiner B, Peterson M, Rivier J, Vale W, Bhasin S. Male contraception: Achievement of reversible azoospermia by combined gonadotropin releasing hormone antagonist and testosterone enanthate Contraception. 46: 193-195. DOI: 10.1016/0010-7824(92)90039-V  0.373
1992 Rivier J, Theobald P, Hoeger C, Craig A, Perrin M, Porter J, Corrigan A, Koerber S, Hagler A, Vale W, Rivier C. GnRH antagonists: A synopsis Contraception. 46: 109-112. DOI: 10.1016/0010-7824(92)90014-K  0.593
1991 Nahon JL, Presset F, Schoepfer R, Vale W. Identification of a Single Melanin-Concentrating Hormone Messenger Ribonucleic Acid in Coho Salmon: Structural Relatedness with 7SL Ribonucleic Acid. Journal of Neuroendocrinology. 3: 173-83. PMID 19215519 DOI: 10.1111/j.1365-2826.1991.tb00260.x  0.37
1991 Roberts VJ, Sawchenko PE, Vale W. Expression of inhibin/activin subunit messenger ribonucleic acids during rat embryogenesis. Endocrinology. 128: 3122-9. PMID 2036981 DOI: 10.1210/Endo-128-6-3122  0.308
1991 Imaki T, Nahan JL, Rivier C, Sawchenko PE, Vale W. Differential regulation of corticotropin-releasing factor mRNA in rat brain regions by glucocorticoids and stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 585-99. PMID 2002354 DOI: 10.1523/Jneurosci.11-03-00585.1991  0.543
1991 Rivier C, Vale W. Effect of recombinant activin-A on gonadotropin secretion in the female rat. Endocrinology. 129: 2463-5. PMID 1935780 DOI: 10.1210/endo-129-5-2463  0.602
1991 Brown MR, Vaughan J, Jimenez LL, Vale W, Baird A. Transforming growth factor-beta: role in mediating serum-induced endothelin production by vascular endothelial cells. Endocrinology. 129: 2355-60. PMID 1935770 DOI: 10.1210/Endo-129-5-2355  0.483
1991 Rivier C, Vale W. Effect of recombinant inhibin on follicle-stimulating hormone secretion by the female rat: interaction with a gonadotropin-releasing hormone antagonist and estrogen. Endocrinology. 129: 2160-5. PMID 1915096 DOI: 10.1210/endo-129-4-2160  0.615
1991 Rivier C, Corrigan A, Vale W. Effect of recombinant human inhibin on gonadotropin secretion by the male rat. Endocrinology. 129: 2155-9. PMID 1915095 DOI: 10.1210/endo-129-4-2155  0.606
1991 Carroll RS, Corrigan AZ, Vale W, Chin WW. Activin stabilizes follicle-stimulating hormone-beta messenger ribonucleic acid levels. Endocrinology. 129: 1721-1726. PMID 1915062 DOI: 10.1210/Endo-129-4-1721  0.356
1991 Kettel LM, Roseff SJ, Chiu TC, Bangah ML, Vale W, Rivier J, Burger HG, Yen SSC. Follicular Arrest during the Midfollicular Phase of the Menstrual Cycle: A Gonadotropin-Releasing Hormone Antagonist Imposed Follicular-Follicular Transition* The Journal of Clinical Endocrinology and Metabolism. 73: 644-649. PMID 1908486 DOI: 10.1210/Jcem-73-3-644  0.341
1991 Rivier C, Schwall R, Mason A, Burton L, Vale W. Effect of recombinant inhibin on gonadotropin secretion during proestrus and estrus in the rat. Endocrinology. 128: 2223-8. PMID 1902163 DOI: 10.1210/endo-128-5-2223  0.599
1991 Feng YJ, Shalts E, Xia LN, Rivier J, Rivier C, Vale W, Ferin M. An inhibitory effects of interleukin-1a on basal gonadotropin release in the ovariectomized rhesus monkey: reversal by a corticotropin-releasing factor antagonist. Endocrinology. 128: 2077-82. PMID 1900786 DOI: 10.1210/endo-128-4-2077  0.504
1991 Corrigan AZ, Bilezikjian LM, Carroll RS, Bald LN, Schmelzer CH, Fendly BM, Mason AJ, Chin WW, Schwall RH, Vale W. Evidence for an autocrine role of activin B within rat anterior pituitary cultures. Endocrinology. 128: 1682-4. PMID 1900235 DOI: 10.1210/Endo-128-3-1682  0.368
1991 Rivier C, Schwall R, Mason A, Burton L, Vaughan J, Vale W. Effect of recombinant inhibin on luteinizing hormone and follicle-stimulating hormone secretion in the rat. Endocrinology. 128: 1548-54. PMID 1900232 DOI: 10.1210/endo-128-3-1548  0.617
1991 Plotsky PM, Kjaer A, Sutton SW, Sawchenko PE, Vale W. Central activin administration modulates corticotropin-releasing hormone and adrenocorticotropin secretion. Endocrinology. 128: 2520-5. PMID 1850353 DOI: 10.1210/Endo-128-5-2520  0.43
1991 Potter E, Behan DP, Fischer WH, Linton EA, Lowry PJ, Vale WW. Cloning and characterization of the cDNAs for human and rat corticotropin releasing factor-binding proteins Nature. 349: 423-426. PMID 1846945 DOI: 10.1038/349423A0  0.305
1991 Gonzalez-Manchon C, Bilezikjian LM, Corrigan AZ, Mellon PL, Vale W. Activin-A modulates gonadotropin-releasing hormone secretion from a gonadotropin-releasing hormone-secreting neuronal cell line Neuroendocrinology. 54: 373-377. PMID 1758579 DOI: 10.1159/000125916  0.424
1991 Attardi B, Vaughan J, Vale W. Regulation of FSH beta messenger ribonucleic acid levels in the rat by endogenous inhibin. Endocrinology. 130: 557-559. PMID 1727723 DOI: 10.1210/Endo.130.1.1727723  0.36
1991 Theobald P, Porter J, Rivier C, Corrigan A, Hook W, Siraganian R, Perrin M, Vale W, Rivier J. Novel gonadotropin-releasing hormone antagonists: peptides incorporating modified N omega-cyanoguanidino moieties. Journal of Medicinal Chemistry. 34: 2395-402. PMID 1714956 DOI: 10.1021/Jm00112A013  0.61
1991 Imaki J, Imaki T, Vale W, Sawchenko PE. Distribution of corticotropin-releasing factor mRNA and immunoreactivity in the central auditory system of the rat. Brain Research. 547: 28-36. PMID 1713530 DOI: 10.1016/0006-8993(91)90571-C  0.33
1991 Anderson LL, Ford JJ, Klindt J, Molina JR, Vale WW, Rivier J. Growth Hormone and Prolactin Secretion in Hypophysial Stalk-Transected Pigs as Affected by Growth Hormone and Prolactin-Releasing and Inhibiting Factors Proceedings of the Society For Experimental Biology and Medicine. 196: 194-202. PMID 1671298 DOI: 10.3181/00379727-196-43179  0.351
1991 Horn F, Bilezikjian LM, Perrin MH, Bosma MM, Windle JJ, Huber KS, Blount AL, Hille B, Vale W, Mellon PL. Intracellular responses to gonadotropin-releasing hormone in a clonal cell line of the gonadotrope lineage. Molecular Endocrinology (Baltimore, Md.). 5: 347-55. PMID 1653891 DOI: 10.1210/mend-5-3-347  0.411
1991 Rivier C, Vale W. Stimulatory effect of interleukin-1 on adrenocorticotropin secretion in the rat: is it modulated by prostaglandins? Endocrinology. 129: 384-8. PMID 1647302 DOI: 10.1210/endo-129-1-384  0.573
1991 Vaccarino F, Feifel D, Rivier J, Vale W. Antagonism of central growth hormone-releasing factor activity selectively attenuates dark-onset feeding in rats The Journal of Neuroscience. 11: 3924-3927. DOI: 10.1523/JNEUROSCI.11-12-03924.1991  0.315
1990 Lee S, Imaki T, Vale W, Rivier C. Effect of prenatal exposure to ethanol on the activity of the hypothalamic-pituitary-adrenal axis of the offspring: Importance of the time of exposure to ethanol and possible modulating mechanisms. Molecular and Cellular Neurosciences. 1: 168-77. PMID 19912768 DOI: 10.1016/1044-7431(90)90022-V  0.581
1990 McMaster D, Itoh H, Maccannell KL, Rivier J, Rivier C, Vale W, Fryer JN, Tran TN, Lederis K. Isolation, Amino-Acid Sequence, Synthesis and Biological Properties of Urotensin I from Hippoglossoides elassodon. Journal of Neuroendocrinology. 2: 875-82. PMID 19215432 DOI: 10.1111/j.1365-2826.1990.tb00654.x  0.54
1990 Bilezikjian LM, Blount AL, Vale WW. The cellular actions of vasopressin on corticotrophs of the anterior pituitary: resistance to glucocorticoid action. Molecular Endocrinology (Baltimore, Md.). 1: 451-8. PMID 3153472 DOI: 10.1210/MEND-1-7-451  0.313
1990 Lenz HJ, Vale WW, Rivier JE. TRH-induced vagal stimulation of duodenal HCO-3 mediated by VIP and muscarinic pathways. The American Journal of Physiology. 257: G677-82. PMID 2531983 DOI: 10.1152/AJPGI.1989.257.5.G677  0.362
1990 Cole BJ, Cador M, Stinus L, Rivier J, Vale W, Koob GF, Le Moal M. Central administration of a CRF antagonist blocks the development of stress-induced behavioral sensitization. Brain Research. 512: 343-6. PMID 2354366 DOI: 10.1016/0006-8993(90)90646-S  0.337
1990 Rivier C, Meunier H, Roberts V, Vale W. Inhibin: role and secretion in the rat. Recent Progress in Hormone Research. 46: 231-57; discussion 2. PMID 2281185 DOI: 10.1016/B978-0-12-571146-3.50013-4  0.613
1990 Cole BJ, Cador M, Stinus L, Rivier C, Rivier J, Vale W, Le Moal M, Koob GF. Critical role of the hypothalamic pituitary adrenal axis in amphetamine-induced sensitization of behavior. Life Sciences. 47: 1715-20. PMID 2250584 DOI: 10.1016/0024-3205(90)90344-Q  0.546
1990 Rivier C, Imaki T, Vale W. Prolonged exposure to alcohol: effect on CRF mRNA levels, and CRF- and stress-induced ACTH secretion in the rat. Brain Research. 520: 1-5. PMID 2169950 DOI: 10.1016/0006-8993(90)91685-A  0.576
1990 Irwin M, Vale W, Rivier C. Central corticotropin-releasing factor mediates the suppressive effect of stress on natural killer cytotoxicity. Endocrinology. 126: 2837-44. PMID 2161737 DOI: 10.1210/endo-126-6-2837  0.567
1990 Bilezikjian LM, Corrigan AZ, Vale W. Activin-A Modulates Growth Hormone Secretion from Cultures of Rat Anterior Pituitary Cells Endocrinology. 126: 2369-2376. PMID 2158424 DOI: 10.1210/Endo-126-5-2369  0.45
1990 Petraglia F, Vaughan J, Vale W. Steroid hormones modulate the release of immunoreactive gonadotropin-releasing hormone from cultured human placental cells. The Journal of Clinical Endocrinology and Metabolism. 70: 1173-8. PMID 2156890 DOI: 10.1210/JCEM-70-4-1173  0.45
1990 Presse F, Nahon J, Fischer WH, Vale W. Structure of the human melanin concentrating hormone mRNA. Molecular Endocrinology. 4: 632-637. PMID 2149166 DOI: 10.1210/Mend-4-4-632  0.383
1990 Young EA, Watson SJ, Kotun J, Haskett RF, Grunhaus L, Murphy-Weinberg V, Vale W, Rivier J, Akil H. Beta-lipotropin-beta-endorphin response to low-dose ovine corticotropin releasing factor in endogenous depression. Preliminary studies. Archives of General Psychiatry. 47: 449-57. PMID 2139563 DOI: 10.1001/ARCHPSYC.1990.01810170049008  0.336
1990 Rivier C, Vale W. Cytokines act within the brain to inhibit luteinizing hormone secretion and ovulation in the rat. Endocrinology. 127: 849-56. PMID 2115435 DOI: 10.1210/endo-127-2-849  0.545
1990 Urban RJ, Pavlou SN, Rivier JE, Vale WW, Dufau ML, Veldhuis JD. Suppressive actions of a gonadotropin-releasing hormone antagonist on luteinizing hormone, follicle-stimulating hormone, and prolactin release in estrogen-deficient postmenopausal women American Journal of Obstetrics and Gynecology. 162: 1255-1260. PMID 2111095 DOI: 10.1016/0002-9378(90)90030-B  0.323
1990 Billestrup N, González-Manchón C, Potter E, Vale W. Inhibition of somatotroph growth and growth hormone biosynthesis by activin in vitro Molecular Endocrinology. 4: 356-362. PMID 2109827 DOI: 10.1210/Mend-4-2-356  0.423
1990 Asa SL, Kovacs K, Stefaneanu L, Horvath E, Billestrup N, Gonzalez-Manchon C, Vale W. Pituitary mammosomatotroph adenomas develop in old mice transgenic for growth hormone-releasing hormone. Experimental Biology and Medicine. 193: 232-235. PMID 2106141 DOI: 10.3181/00379727-193-3-Rc1  0.394
1990 Struthers RS, Tanaka G, Koerber SC, Solmajer T, Baniak EL, Gierasch LM, Vale W, Rivier J, Hagler AT. Design of biologically active, conformationally constrained GnRH antagonists Proteins: Structure, Function and Genetics. 8: 295-304. PMID 2091022 DOI: 10.1002/Prot.340080403  0.33
1990 Luo D, McKeown BA, Rivier J, Vale W. In vitro responses of rainbow trout (Oncorhynchus mykiss) somatotrophs to carp growth hormone-releasing factor (GRF) and somatostatin. General and Comparative Endocrinology. 80: 288-298. PMID 1981568 DOI: 10.1016/0016-6480(90)90173-J  0.432
1990 Sundaram K, Didolkar AK, Keizer-Zucker A, DeJesus W, Rivier J, Vale W, Bardin CW. A 90-day subcutaneous toxicity and fertility study of a LHRH antagonist in rats. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 14: 734-44. PMID 1694507 DOI: 10.1016/0272-0590(90)90298-X  0.352
1989 Peterson ME, Palkovits M, Chiueh CC, Graves TK, Mezey E, Vale W, Krieger DT. Biogenic Amine and Corticotrophin-Releasing Factor Concentrations in Hypothalamic Paraventricular Nucleus and Biogenic Amine Levels in the Median Eminence of Normal Dogs, Chronic Dexamethasone-Treated Dogs, and Dogs with Naturally-Occurring Pituitary-Dependent Hyperadrenocorticism (Canine Cushing's Disease). Journal of Neuroendocrinology. 1: 169-171. PMID 19210450 DOI: 10.1111/J.1365-2826.1989.Tb00098.X  0.367
1989 Petraglia F, Calza L, Giardino L, Sutton S, Marrama P, Rivier J, Genazzani AR, Vale W. Identification of Immunoreactive Neuropeptide-γ in Human Placenta: Localization, Secretion, and Binding Sites* Endocrinology. 124: 2016-2022. PMID 2924733 DOI: 10.1210/Endo-124-4-2016  0.354
1989 Samson WK, Bianchi R, Mogg RJ, Rivier J, Vale W, Melin P. Oxytocin mediates the hypothalamic action of vasoactive intestinal peptide to stimulate prolactin secretion Endocrinology. 124: 812-819. PMID 2912703 DOI: 10.1210/Endo-124-2-812  0.476
1989 Imaki T, Nahon JL, Sawchenko PE, Vale W. Widespread expression of corticotropin-releasing factor messenger RNA and immunoreactivity in the rat olfactory bulb. Brain Research. 496: 35-44. PMID 2804647 DOI: 10.1016/0006-8993(89)91050-0  0.32
1989 Tsafriri A, Vale W, Hsueh AJW. Effects of transforming growth factors and inhibin-related proteins on rat preovulatory graafian follicles in vitro. Endocrinology. 125: 1857-1862. PMID 2791970 DOI: 10.1210/Endo-125-4-1857  0.404
1989 Widmaier EP, Lim AT, Vale W. Secretion of corticotropin-releasing factor from cultured rat hypothalamic cells: effects of catecholamines. Endocrinology. 124: 583-90. PMID 2783568 DOI: 10.1210/Endo-124-2-583  0.479
1989 Kitayama I, Cintra A, Janson AM, Fuxe K, Agnati LF, Eneroth P, Aronsson M, Härfstrand A, Steinbush HWM, Visser TJ, Goldstein M, Vale W, Gustafsson JÅ. Chronic immobilization stress: evidence for decreases of 5-hydroxy-tryptamine immunoreactivity and for increases of glucocorticoid receptor immunoreactivity in various brain regions of the male rat. Journal of Neural Transmission. 77: 93-130. PMID 2760606 DOI: 10.1007/Bf01248925  0.354
1989 Gonzalez-Manchon C, Vale W. Activin-A, Inhibin and Transforming Growth Factor-β Modulate Growth of Two Gonadal Cell Lines* Endocrinology. 125: 1666-1672. PMID 2759039 DOI: 10.1210/Endo-125-3-1666  0.33
1989 Vaughan JM, Fischer WH, Hoeger C, Rivier J, Vale W. Characterization of melanin-concentrating hormone from rat hypothalamus Endocrinology. 125: 1660-1665. PMID 2759038 DOI: 10.1210/Endo-125-3-1660  0.359
1989 Vaughan JM, Rivier J, Corrigan AZ, McClintock R, Campen CA, Jolley D, Voglmayr JK, Bardin CW, Rivier C, Vale W. Detection and purification of inhibin using antisera generated against synthetic peptide fragments. Methods in Enzymology. 168: 588-617. PMID 2725313 DOI: 10.1016/0076-6879(89)68044-5  0.558
1989 Roberts V, Meunier H, Sawchenko PE, Vale W. Differential production and regulation of inhibin subunits in rat testicular cell types. Endocrinology. 125: 2350-9. PMID 2676482 DOI: 10.1210/Endo-125-5-2350  0.31
1989 Petraglia F, Vaughan J, Vale W. Inhibin and activin modulate the release of gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone from cultured human placental cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 5114-7. PMID 2662194 DOI: 10.1073/PNAS.86.13.5114  0.444
1989 Rivier C, Vale W. In the rat, interleukin-1 alpha acts at the level of the brain and the gonads to interfere with gonadotropin and sex steroid secretion. Endocrinology. 124: 2105-9. PMID 2651094 DOI: 10.1210/endo-124-5-2105  0.563
1989 Rivier C, Vale W. Immunoreactive inhibin secretion by the hypophysectomized female rat: demonstration of the modulating effect of gonadotropin-releasing hormone and estrogen through a direct ovarian site of action. Endocrinology. 124: 195-8. PMID 2642415 DOI: 10.1210/endo-124-1-195  0.632
1989 Meunier H, Roberts VJ, Sawchenko PE, Cajander SB, Hsueh AJ, Vale W. Periovulatory changes in the expression of inhibin alpha-, beta A-, and beta B-subunits in hormonally induced immature female rats. Molecular Endocrinology (Baltimore, Md.). 3: 2062-9. PMID 2628740 DOI: 10.1210/Mend-3-12-2062  0.326
1989 Rivier C, Vale W, Brown M. In the rat, interleukin-1 alpha and -beta stimulate adrenocorticotropin and catecholamine release. Endocrinology. 125: 3096-102. PMID 2573510 DOI: 10.1210/endo-125-6-3096  0.479
1989 Petraglia F, Sutton S, Vale W. Neurotransmitters and peptides modulate the release of immunoreactive corticotropin-releasing factor from cultured human placental cells. American Journal of Obstetrics and Gynecology. 160: 247-51. PMID 2563197 DOI: 10.1016/0002-9378(89)90130-0  0.419
1989 LaPolt PS, Soto D, Su JG, Campen CA, Vaughan J, Vale W, Hsueh AJ. Activin stimulation of inhibin secretion and messenger RNA levels in cultured granulosa cells. Molecular Endocrinology (Baltimore, Md.). 3: 1666-73. PMID 2558301 DOI: 10.1210/mend-3-10-1666  0.35
1989 Rivier C, Chizzonite R, Vale W. In the mouse, the activation of the hypothalamic-pituitary-adrenal axis by a lipopolysaccharide (endotoxin) is mediated through interleukin-1. Endocrinology. 125: 2800-5. PMID 2555127 DOI: 10.1210/endo-125-6-2800  0.537
1989 Perrin MH, Haas Y, Porter J, Rivier J, Vale W. The gonadotropin-releasing hormone pituitary receptor interacts with a guanosine triphosphate-binding protein: differential effects of guanyl nucleotides on agonist and antagonist binding. Endocrinology. 124: 798-804. PMID 2536322 DOI: 10.1210/endo-124-2-798  0.362
1989 Roberts V, Meunier H, Vaughan J, Rivier J, Rivier C, Vale W, Sawchenko P. Production and regulation of inhibin subunits in pituitary gonadotropes. Endocrinology. 124: 552-4. PMID 2535814 DOI: 10.1210/Endo-124-1-552  0.562
1989 Struthers RS, Perrin MH, Vale W. Nucleotide regulation of growth hormone-releasing factor binding to rat pituitary receptors. Endocrinology. 124: 24-9. PMID 2535806 DOI: 10.1210/ENDO-124-1-24  0.39
1989 Carroll RS, Corrigan AZ, Gharib SD, Vale W, Chin WW. Inhibin, Activin, and Follistatin: Regulation of Follicle-Stimulating Hormone Messenger Ribonucleic Acid Levels Molecular Endocrinology. 3: 1969-1976. PMID 2516876 DOI: 10.1210/Mend-3-12-1969  0.319
1989 Nemeroff CB, Krishnan KR, Belkin BM, Ritchie JC, Clark C, Vale WW, Rivier JE, Thorner MO. Growth hormone response to growth hormone releasing factor in Alzheimer's disease. Neuroendocrinology. 50: 663-6. PMID 2515465 DOI: 10.1159/000125296  0.389
1989 Stefaneanu L, Kovacs K, Horvath E, Asa SL, Losinski NE, Billestrup N, Price J, Vale W. Adenohypophysial changes in mice transgenic for human growth hormone-releasing factor: a histological, immunocytochemical, and electron microscopic investigation. Endocrinology. 125: 2710-2718. PMID 2507296 DOI: 10.1210/Endo-125-5-2710  0.38
1989 Rivier C, Roberts V, Vale W. Possible role of luteinizing hormone and follicle-stimulating hormone in modulating inhibin secretion and expression during the estrous cycle of the rat. Endocrinology. 125: 876-82. PMID 2502378 DOI: 10.1210/endo-125-2-876  0.602
1989 Rivier C, Vale W. Immunoneutralization of endogenous inhibin modifies hormone secretion and ovulation rate in the rat. Endocrinology. 125: 152-7. PMID 2500324 DOI: 10.1210/endo-125-1-152  0.597
1989 Vance ML, Kaiser DL, Martha PM, Furlanetto R, Rivier J, Vale W, Thorner MO. Lack of in vivo somatotroph desensitization or depletion after 14 days of continuous growth hormone (GH)-releasing hormone administration in normal men and a GH-deficient boy. The Journal of Clinical Endocrinology and Metabolism. 68: 22-8. PMID 2491864 DOI: 10.1210/jcem-68-1-22  0.34
1989 Rivier C, Meunier H, Roberts V, Vale W. Possible involvement of inhibin in altered follicle-stimulating hormone (FSH) secretion during dissociated luteinizing hormone (LH) and FSH release: unilateral castration and experimental cryptorchidism. Biology of Reproduction. 41: 967-81. PMID 2483127 DOI: 10.1095/Biolreprod41.5.967  0.566
1989 Nahon JL, Presse F, Bittencourt JC, Sawchenko PE, Vale W. The rat melanin-concentrating hormone messenger ribonucleic acid encodes multiple putative neuropeptides coexpressed in the dorsolateral hypothalamus. Endocrinology. 125: 2056-65. PMID 2477226 DOI: 10.1210/Endo-125-4-2056  0.395
1989 Mortola JF, Sathanandan M, Pavlou S, Dahl KD, Hsueh AJW, Rivier J, Vale W, Yen SSC. Suppression of bioactive and immunoreactive follicle-stimulating hormone and luteinizing hormone levels by a potent gonadotropin-releasing hormone antagonist: pharmacodynamic studies. Fertility and Sterility. 51: 957-963. DOI: 10.1016/S0015-0282(16)60725-2  0.394
1988 Sapolsky RM, Packan DR, Vale WW. Glucocorticoid toxicity in the hippocampus: in vitro demonstration. Brain Research. 453: 367-71. PMID 3401775 DOI: 10.1016/0006-8993(88)90180-1  0.401
1988 Lin HR, Van der Kraak G, Zhou XJ, Liang JY, Peter RE, Rivier JE, Vale WW. Effects of [D-Arg6, Trp7, Leu8, Pro9NEt]-luteinizing hormone-releasing hormone (sGnRH-A) and [D-Ala6, Pro9NEt]-luteinizing hormone-releasing hormone (LHRH-A), in combination with pimozide or domperidone, on gonadotropin release and ovulation in the Chinese loach and common carp. General and Comparative Endocrinology. 69: 31-40. PMID 3282976 DOI: 10.1016/0016-6480(88)90049-4  0.348
1988 Rivier J, Kupryszewski G, Varga J, Porter J, Rivier C, Perrin M, Hagler A, Struthers S, Corrigan A, Vale W. Design of potent cyclic gonadotropin releasing hormone antagonists. Journal of Medicinal Chemistry. 31: 677-82. PMID 3279211 DOI: 10.1021/Jm00398A030  0.554
1988 Campen CA, Vale W. Characterization of activin A binding sites on the human leukemia cell line K562 Biochemical and Biophysical Research Communications. 157: 844-849. PMID 3202879 DOI: 10.1016/S0006-291X(88)80326-7  0.328
1988 Meunier H, Cajander SB, Roberts VJ, Rivier C, Sawchenko PE, Hsueh AJ, Vale W. Rapid changes in the expression of inhibin alpha-, beta A-, and beta B-subunits in ovarian cell types during the rat estrous cycle. Molecular Endocrinology (Baltimore, Md.). 2: 1352-63. PMID 3146021 DOI: 10.1210/Mend-2-12-1352  0.503
1988 Hall JE, Brodie TD, Badger TM, Rivier J, Vale W, Conn PM, Schoenfeld D, Crowley WF. Evidence of differential control of FSH and LH secretion by gonadotropin-releasing hormone (GnRH) from the use of a GnRH antagonist. The Journal of Clinical Endocrinology and Metabolism. 67: 524-31. PMID 3137243 DOI: 10.1210/Jcem-67-3-524  0.426
1988 Campen CA, Vale W. Interaction between Purified Ovine Inhibin and Steroids on the Release of Gonadotropins from Cultured Rat Pituitary Cells Endocrinology. 123: 1320-1328. PMID 3136005 DOI: 10.1210/Endo-123-3-1320  0.426
1988 Rivier J, Rivier C, Galyean R, Yammamoto G, Vale W. Potent long-acting growth hormone releasing factor analogues. Annals of the New York Academy of Sciences. 527: 44-50. PMID 3133968 DOI: 10.1111/j.1749-6632.1988.tb26971.x  0.592
1988 Rivier C, Cajander S, Vaughan J, Hsueh AJ, Vale W. Age-dependent changes in physiological action, content, and immunostaining of inhibin in male rats. Endocrinology. 123: 120-6. PMID 3133192 DOI: 10.1210/endo-123-1-120  0.546
1988 Bicsak TA, Cajander SB, Vale W, Hsueh AJW. Inhibin: studies of stored and secreted forms by biosynthetic labeling and immunodetection in cultured rat granulosa cells. Endocrinology. 122: 741-748. PMID 3123204 DOI: 10.1210/Endo-122-2-741  0.323
1988 Vale W, Rivier C, Hsueh A, Campen C, Meunier H, Bicsak T, Vaughan J, Corrigan A, Bardin W, Sawchenko P. Chemical and biological characterization of the inhibin family of protein hormones. Recent Progress in Hormone Research. 44: 1-34. PMID 3064204 DOI: 10.1016/B978-0-12-571144-9.50005-3  0.573
1988 Boyle M, Yamamoto G, Chen M, Rivier J, Vale W. Interleukin 1 prevents loss of corticotropic responsiveness to β-adrenergic stimulation in vitro Proceedings of the National Academy of Sciences of the United States of America. 85: 5556-5560. PMID 2899892 DOI: 10.1073/Pnas.85.15.5556  0.42
1988 Kaler LW, Vale W, Critchlow V. Effects of somatostatin antiserum on growth hormone levels in rats with periventricular lesions in the anterior hypothalamus. Brain Research. 447: 384-388. PMID 2898964 DOI: 10.1016/0006-8993(88)91145-6  0.336
1988 Vaccarino FJ, Feifel D, Rivier J, Vale W, Koob GF. Centrally administered hypothalamic growth hormone-releasing factor stimulates food intake in free-feeding rats. Peptides. 9: 35-8. PMID 2856650 DOI: 10.1016/0196-9781(88)90220-3  0.347
1988 Rivier C, Vale W. Interaction between ethanol and stress on ACTH and beta-endorphin secretion. Alcoholism, Clinical and Experimental Research. 12: 206-10. PMID 2837103 DOI: 10.1111/J.1530-0277.1988.Tb00181.X  0.607
1988 Ikuyama S, Natori S, Nawata H, Kato K, Ibayashi H, Kariya T, Sakai T, Rivier J, Vale W. Characterization of growth hormone-releasing hormone receptors in pituitary adenomas from patients with acromegaly. The Journal of Clinical Endocrinology and Metabolism. 66: 1265-71. PMID 2836473 DOI: 10.1210/jcem-66-6-1265  0.391
1988 Pavlou SN, Dahl KD, Wakefield G, Rivier J, Vale W, Hsueh AJW, Lindner J. Maintenance of the ratio of bioactive to immunoreactive follicle-stimulating hormone in normal men during chronic luteinizing hormone-releasing hormone agonist administration. The Journal of Clinical Endocrinology and Metabolism. 66: 1005-1009. PMID 2834409 DOI: 10.1210/Jcem-66-5-1005  0.387
1988 Schwartz J, Vale W. Dissociation of the adrenocorticotropin secretory responses to corticotropin-releasing factor (CRF) and vasopressin or oxytocin by using a specific cytotoxic analog of CRF. Endocrinology. 122: 1695-1700. PMID 2831039 DOI: 10.1210/Endo-122-4-1695  0.425
1988 Meunier H, Rivier C, Evans RM, Vale W. Gonadal and extragonadal expression of inhibin alpha, beta A, and beta B subunits in various tissues predicts diverse functions. Proceedings of the National Academy of Sciences of the United States of America. 85: 247-51. PMID 2829170 DOI: 10.1073/Pnas.85.1.247  0.508
1988 Krishnan KR, Manepalli AN, Ritchie JC, Rayasam K, Melville ML, Daughtry G, Thorner MO, Rivier JE, Vale WW, Nemeroff CB. Growth hormone-releasing factor stimulation test in depression. The American Journal of Psychiatry. 145: 90-2. PMID 2827532 DOI: 10.1176/AJP.145.1.90  0.393
1988 Sawchenko PE, Plotsky PM, Pfeiffer SW, Cunningham ET, Vaughan J, Rivier J, Vale W. Inhibin beta in central neural pathways involved in the control of oxytocin secretion. Nature. 334: 615-7. PMID 2457171 DOI: 10.1038/334615A0  0.329
1987 Yu J, Shao L, Lemas V, Yu AL, Vaughan J, Rivier J, Vale W. Importance of fsh releasing protein and inhibin in erythrodifferentiation Nature. 330: 765-767. PMID 3696240 DOI: 10.1038/330765A0  0.381
1987 Petraglia F, Sutton S, Vale W, Plotsky P. Corticotropin-releasing factor decreases plasma luteinizing hormone levels in female rats by inhibiting gonadotropin-releasing hormone release into hypophysial-portal circulation Endocrinology. 120: 1083-1088. PMID 3542513 DOI: 10.1210/ENDO-120-3-1083  0.451
1987 Irwin MR, Vale W, Britton KT. Central corticotropin-releasing factor suppresses natural killer cytotoxicity Brain Behavior and Immunity. 1: 81-87. PMID 3502536 DOI: 10.1016/0889-1591(87)90009-2  0.414
1987 Rivier C, Vale W. Diminished responsiveness of the hypothalamic-pituitary-adrenal axis of the rat during exposure to prolonged stress: a pituitary-mediated mechanism. Endocrinology. 121: 1320-8. PMID 3498626 DOI: 10.1210/endo-121-4-1320  0.591
1987 Tazi A, Dantzer R, Le Moal M, Rivier J, Vale W, Koob GF. Corticotropin-releasing factor antagonist blocks stress-induced fighting in rats. Regulatory Peptides. 18: 37-42. PMID 3498188 DOI: 10.1016/0167-0115(87)90048-6  0.376
1987 Hsueh AJ, Dahl KD, Vaughan J, Tucker E, Rivier J, Bardin CW, Vale W. Heterodimers and homodimers of inhibin subunits have different paracrine action in the modulation of luteinizing hormone-stimulated androgen biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 84: 5082-6. PMID 3474640 DOI: 10.1073/PNAS.84.14.5082  0.399
1987 Petraglia F, Lim AT, Vale W. Adenosine 3',5'-monophosphate, prostaglandins, and epinephrine stimulate the secretion of immunoreactive gonadotropin-releasing hormone from cultured human placental cells. The Journal of Clinical Endocrinology and Metabolism. 65: 1020-5. PMID 3312277 DOI: 10.1210/jcem-65-5-1020  0.409
1987 Petraglia F, Sawchenko P, Lim AT, Rivier J, Vale W. Localization, secretion, and action of inhibin in human placenta. Science (New York, N.Y.). 237: 187-9. PMID 3299703 DOI: 10.1126/Science.3299703  0.439
1987 Bilezikjian LM, Woodgett JR, Hunter T, Vale WW. Phorbol ester-induced down-regulation of protein kinase C abolishes vasopressin-mediated responses in rat anterior pituitary cells Molecular Endocrinology (Baltimore, Md.). 1: 555-560. PMID 3153477 DOI: 10.1210/Mend-1-8-555  0.31
1987 Rivier C, Vale W, Rivier J. Studies of the inhibin family of hormones: a review. Hormone Research. 28: 104-18. PMID 3136065 DOI: 10.1159/000180934  0.558
1987 Billestrup N, Mitchell RL, Vale W, Verma IM. Growth hormone-releasing factor induces c-fos expression in cultured primary pituitary cells. Molecular Endocrinology (Baltimore, Md.). 1: 300-5. PMID 3135482 DOI: 10.1210/Mend-1-4-300  0.381
1987 Rivier C, Rivier J, Vale W. Inhibin: measurement and role in the rat. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 14: 273-6. PMID 3115918 DOI: 10.1016/0883-2897(87)90002-X  0.499
1987 Cintra A, Fuxe K, Härfstrand A, Agnati LF, Wikström AC, Okret S, Vale W, Gustafsson JÅ. Presence of glucocorticoid receptor immunoreactivity in corticotrophin releasing factor and in growth hormone releasing factor immunoreactive neurons of the rat di- and telencephalon Neuroscience Letters. 77: 25-30. PMID 3110702 DOI: 10.1016/0304-3940(87)90601-X  0.409
1987 Pavlou SN, Interlandi JW, Wakefield G, Island DP, Rivier J, Vale W, Kovacs WJ. Gonadotropins and testosterone escape from suppression during prolonged luteinizing hormone-releasing hormone antagonist administration in normal men The Journal of Clinical Endocrinology and Metabolism. 64: 1070-1074. PMID 3104387 DOI: 10.1210/Jcem-64-5-1070  0.377
1987 Rivier C, Vale W. Inhibin: measurement and role in the immature female rat. Endocrinology. 120: 1688-90. PMID 3104016 DOI: 10.1210/endo-120-4-1688  0.528
1987 Petraglia F, Sawchenko PE, Rivier J, Vale W. Evidence for local stimulation of ACTH secretion by corticotropin-releasing factor in human placenta. Nature. 328: 717-9. PMID 3039377 DOI: 10.1038/328717A0  0.469
1987 Bicsak TA, Vale W, Vaughan J, Tucker EM, Cappel S, Hsueh AJ. Hormonal regulation of inhibin production by cultured Sertoli cells. Molecular and Cellular Endocrinology. 49: 211-7. PMID 3030853 DOI: 10.1016/0303-7207(87)90215-2  0.408
1987 Zukin SR, Zukin RS, Vale W, Rivier J, Nichtenhauser R, Snell LD, Johnson KM. An endogenous ligand of the brain sigma/PCP receptor antagonizes NMDA-induced neurotransmitter release. Brain Research. 416: 84-9. PMID 2887250 DOI: 10.1016/0006-8993(87)91499-5  0.384
1987 Petraglia F, Vale W, Rivier C. Beta-endorphin and dynorphin participate in the stress-induced release of prolactin in the rat. Neuroendocrinology. 45: 338-42. PMID 2884585 DOI: 10.1159/000124756  0.556
1987 Rivier C, Vale W. Cocaine stimulates adrenocorticotropin (ACTH) secretion through a corticotropin-releasing factor (CRF)-mediated mechanism. Brain Research. 422: 403-6. PMID 2823980 DOI: 10.1016/0006-8993(87)90953-X  0.56
1987 Sapolsky R, Rivier C, Yamamoto G, Plotsky P, Vale W. Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor. Science (New York, N.Y.). 238: 522-4. PMID 2821621 DOI: 10.1126/science.2821621  0.662
1987 Schwartz J, Penke B, Rivier J, Vale W. A new cytotoxin specific for the target cells of corticotropin-releasing factor Endocrinology. 121: 1454-1460. PMID 2820698 DOI: 10.1210/Endo-121-4-1454  0.423
1987 Thorner MO, Vance ML, Martha P, Blizzard RM, Rogol AD, Brook C, Smith P, Klingensmith G, Burr I, Najjar J, Furlanetto R, Rivier J, Vale W. Growth Hormone Releasing Hormone: Therapeutic Potentials Endocrinologia Japonica. 34: 51-57. DOI: 10.1507/Endocrj1954.34.Supplement_51  0.404
1987 Biffignandi P, Molinatti GM, Zoppi S, Cocconi M, Serio M, Martini L, Motta M, Pugeat M, Lejeune H, Dechaud H, Emptoz-Bonneton A, Fleury M, Charrié A, Tourniaire J, Forest MG, ... ... Vale W, et al. Subject Index, Vol. 28, 1987 Hormone Research in Paediatrics. 28: 291-292. DOI: 10.1159/000180955  0.409
1987 Biffignandi P, Molinatti GM, Zoppi S, Cocconi M, Serio M, Martini L, Motta M, Pugeat M, Lejeune H, Dechaud H, Emptoz-Bonneton A, Fleury M, Charrié A, Tourniaire J, Forest MG, ... ... Vale W, et al. Contents, Vol. 28, 1987 Hormone Research in Paediatrics. 28. DOI: 10.1159/000180929  0.419
1987 Rivier J, Rivier C, Perrin M, Hagler A, Struthers S, Pandol S, Brown M, Kupryszewski G, Chadhuri M, Vale W. Competitive antagonists of peptide hormones Regulatory Peptides. 19: 135. DOI: 10.1016/0167-0115(87)90147-9  0.54
1986 Fuxe K, Andersson K, Härfstrand A, Agnati LF, Eneroth P, Janson AM, Vale W, Thorner M, Goldstein M. Medianosomes as integrative units in the external layer of the median eminence. Studies on grf/catecholamine and somatostatin/catecholamine interactions in the hypothalamus of the male rat. Neurochemistry International. 9: 155-70. PMID 20493113 DOI: 10.1016/0197-0186(86)90044-6  0.425
1986 Pavlou SN, Interlandi JW, Wakefield G, Rivier J, Vale W, Rabin D. Heterogeneity of sperm density profiles following 16-week therapy with continuous infusion of high-dose LHRH analog plus testosterone. Journal of Andrology. 7: 228-233. PMID 3528106 DOI: 10.1002/J.1939-4640.1986.Tb00920.X  0.346
1986 Thorner MO, Vance ML, Evans WS, Rogol AD, Rivier J, Vale W, Blizzard RM. Clinical studies with ghrh in man Hormone Research in Paediatrics. 24: 91-98. PMID 3093355 DOI: 10.1159/000180547  0.364
1986 Wehrenberg WB, Esch F, Baird A, Ying S-, Bölen P, Ling N, Thorner MO, Zapf J, Froesch ER, Brande JLVd, Jansen M, Hoogerbrugge CM, Pagter-Holthuizen Pd, Buul-Offers SCv, Schaik FMAv, ... ... Vale W, et al. Therapeutic Agents Produced by Genetic Engineering: Quo Vadis? The Example of Growth Hormone and Its Releasing Factor Hormone Research in Paediatrics. 24: 201-228. PMID 3093353 DOI: 10.1159/000180560  0.342
1986 Thorner MO, Vance ML, Evans WS, Ho K, Rogol AD, Blizzard RM, Furlanetto R, Rivier J, Vale W. Growth hormone releasing factor and somatomedin C production: extrahypothalamic localization and possible functional significance. Acta Endocrinologica. Supplementum. 276: 34-40. PMID 3092530 DOI: 10.1530/ACTA.0.111S0034  0.43
1986 Rivier C, Rivier J, Vale W. Inhibin-mediated feedback control of follicle-stimulating hormone secretion in the female rat. Science (New York, N.Y.). 234: 205-8. PMID 3092356 DOI: 10.1126/Science.3092356  0.62
1986 Vale W, Vaughan J, Jolley D, Yamamoto G, Bruhn T, Seifert H, Perrin M, Thorner M, Rivier J. [28] Assay of growth hormone-releasing factor Methods in Enzymology. 124: 389-402. PMID 3086662 DOI: 10.1016/0076-6879(86)24030-6  0.396
1986 Scanes CG, Harvey S, Rivier J, Vale W. Stimulation of in-vivo growth hormone secretion in young chickens by rat hypothalamic growth hormone-releasing factor and synthetic analogues. Journal of Endocrinology. 108: 413-416. PMID 3084695 DOI: 10.1677/Joe.0.1080413  0.46
1986 Vance ML, Kaiser DL, Rivier J, Vale W, Thorner MO. Dual effects of growth hormone (GH)-releasing hormone infusion in normal men: somatotroph desensitization and increase in releasable GH. The Journal of Clinical Endocrinology and Metabolism. 62: 591-4. PMID 3080467 DOI: 10.1210/jcem-62-3-591  0.407
1986 Bicsak TA, Tucker EM, Cappel S, Vaughan J, Rivier J, Vale W, Hsueh AJ. Hormonal regulation of granulosa cell inhibin biosynthesis. Endocrinology. 119: 2711-9. PMID 3023019 DOI: 10.1210/endo-119-6-2711  0.453
1986 Schwartz J, Billestrup N, Perrin M, Marilyn J, Vale W. Identification of corticotropin-releasing factor (CRF) target cells and effects of dexamethasone on binding in anterior pituitary using a fluorescent analog of CRF. Endocrinology. 119: 2376-2382. PMID 3021441 DOI: 10.1210/Endo-119-5-2376  0.357
1986 Walker CD, Sapolsky RM, Meaney MJ, Vale WW, Rivier CL. Increased pituitary sensitivity to glucocorticoid feedback during the stress nonresponsive period in the neonatal rat. Endocrinology. 119: 1816-21. PMID 3019645 DOI: 10.1210/endo-119-4-1816  0.645
1986 Bruhn TO, Sutton SW, Plotsky PM, Vale WW. Central administration of corticotropin-releasing factor modulates oxytocin secretion in the rat. Endocrinology. 119: 1558-63. PMID 3019636 DOI: 10.1210/endo-119-4-1558  0.341
1986 Chen FM, Bilezikjian LM, Perrin MH, Rivier J, Vale W. Corticotropin releasing factor receptor-mediated stimulation of adenylate cyclase activity in the rat brain. Brain Research. 381: 49-57. PMID 3019476 DOI: 10.1016/0006-8993(86)90688-8  0.411
1986 Billestrup N, Swanson LW, Vale W. Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro. Proceedings of the National Academy of Sciences of the United States of America. 83: 6854-7. PMID 3018748 DOI: 10.1073/Pnas.83.18.6854  0.404
1986 Mayo KE, Cerelli GM, Spiess J, Rivier J, Rosenfeld MG, Evans RM, Vale W. Inhibin A-subunit cDNAs from porcine ovary and human placenta Proceedings of the National Academy of Sciences of the United States of America. 83: 5849-5853. PMID 3016724 DOI: 10.1073/Pnas.83.16.5849  0.597
1986 Wehrenberg WB, Seifert H, Bilezikjian LM, Vale W. Down-Regulation of Growth Hormone Releasing Factor Receptors following Continuous Infusion of Growth Hormone Releasing Factor in vivo Neuroendocrinology. 43: 266-268. PMID 3014366 DOI: 10.1159/000124538  0.458
1986 Bilezikjian LM, Seifert H, Vale W. Desensitization to growth hormone-releasing factor (GRF) is associated with down-regulation of GRF-binding sites Endocrinology. 118: 2045-2052. PMID 3009146 DOI: 10.1210/Endo-118-5-2045  0.383
1986 Britton KT, Lee G, Vale W, Rivier J, Koob GF. Corticotropin releasing factor (CRF) receptor antagonist blocks activating and 'anxiogenic' actions of CRF in the rat. Brain Research. 369: 303-6. PMID 3008937 DOI: 10.1016/0006-8993(86)90539-1  0.428
1986 Walker CD, Perrin M, Vale W, Rivier C. Ontogeny of the stress response in the rat: role of the pituitary and the hypothalamus. Endocrinology. 118: 1445-51. PMID 3004915 DOI: 10.1210/endo-118-4-1445  0.576
1986 Rivier C, Rivier J, Vale W. Stress-induced inhibition of reproductive functions: role of endogenous corticotropin-releasing factor. Science (New York, N.Y.). 231: 607-9. PMID 3003907 DOI: 10.1126/Science.3003907  0.624
1986 Petraglia F, Vale W, Rivier C. Opioids act centrally to modulate stress-induced decrease in luteinizing hormone in the rat. Endocrinology. 119: 2445-50. PMID 2877862 DOI: 10.1210/endo-119-6-2445  0.579
1986 Schusdziarra V, Schmid R, Bender H, Schusdziarra M, Rivier J, Vale W, Classen M. Effect of vasoactive intestinal peptide, peptide histidine isoleucine and growth hormone-releasing factor-40 on bombesin-like immunoreactivity, somatostatin and gastrin release from the perfused rat stomach. Peptides. 7: 127-133. PMID 2872659 DOI: 10.1016/0196-9781(86)90072-0  0.353
1986 Rivier JE, Porter J, Rivier CL, Perrin M, Corrigan A, Hook WA, Siraganian RP, Vale WW. New effective gonadotropin releasing hormone antagonists with minimal potency for histamine release in vitro. Journal of Medicinal Chemistry. 29: 1846-51. PMID 2428978  0.589
1986 Pandol SJ, Dharmsathaphorn K, Schoeffield MS, Vale W, Rivier J. Vasoactive intestinal peptide receptor antagonist [4Cl-D-Phe6, Leu17] VIP. American Journal of Physiology-Gastrointestinal and Liver Physiology. 250: 553-557. PMID 2421587 DOI: 10.1152/Ajpgi.1986.250.4.G553  0.406
1986 Norman RL, Rivier J, Vale W, Spies HG. Inhibition of estradiol-induced gonadotropin release in ovariectomized rhesus macaques by a gonadotropin-releasing hormone antagonist. Fertility and Sterility. 45: 288-291. DOI: 10.1016/S0015-0282(16)49169-7  0.448
1985 Smith MA, Yamamoto G, Vale WW. Somatostatin desensitization in rat anterior pituitary cells. Molecular and Cellular Endocrinology. 37: 311-8. PMID 6209179 DOI: 10.1016/0303-7207(84)90101-1  0.341
1985 Rivier J, Spiess J, McClintock R, Vaughan J, Vale W. Purification and partial characterization of inhibin from porcine follicular fluid Biochemical and Biophysical Research Communications. 133: 120-127. PMID 4074357 DOI: 10.1016/0006-291X(85)91849-2  0.317
1985 Fuxe K, Wikström A, Okret S, Agnati LF, Härfstrand A, Yu Z, Granholm L, Zoli M, Vale W, Gustafsson J. Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor. Endocrinology. 117: 1803-1812. PMID 4042964 DOI: 10.1210/Endo-117-5-1803  0.32
1985 Evans WS, Vance ML, Kaiser DL, Sellers RP, Borges JL, Downs TR, Frohman LA, Rivier J, Vale W, Thorner MO. Effects of intravenous, subcutaneous, and intranasal administration of growth hormone (GH)-releasing hormone-40 on serum GH concentrations in normal men. The Journal of Clinical Endocrinology and Metabolism. 61: 846-50. PMID 3930551 DOI: 10.1210/jcem-61-5-846  0.397
1985 Britton KT, Morgan J, Rivier J, Vale W, Koob GF. Chlordiazepoxide attenuates response suppression induced by corticotropin-releasing factor in the conflict test. Psychopharmacology. 86: 170-4. PMID 3927353 DOI: 10.1007/BF00431704  0.363
1985 Styne DM, Harris DA, Egli CA, Conte FA, Kaplan SL, Rivier J, Vale W, Grumbach MM. Treatment of true precocious puberty with a potent luteinizing hormone-releasing factor agonist: effect on growth, sexual maturation, pelvic sonography, and the hypothalamic-pituitary-gonadal axis. The Journal of Clinical Endocrinology and Metabolism. 61: 142-51. PMID 3923027 DOI: 10.1210/jcem-61-1-142  0.315
1985 Grady RR, Shin L, Charlesworth MC, Cohen-Becker IR, Smith M, Rivier C, Rivier J, Vale W, Schwartz NB. Differential suppression of follicle-stimulating hormone and luteinizing hormone secretion in vivo by a gonadotropin-releasing hormone antagonist. Neuroendocrinology. 40: 246-52. PMID 3921860 DOI: 10.1159/000124081  0.551
1985 Schwartz NB, Rivier C, Rivier J, Vale WW. Effect of gonadotropin-releasing hormone antagonists on serum follicle-stimulating hormone and luteinizing hormone under conditions of singular follicle-stimulating hormone secretion. Biology of Reproduction. 32: 391-8. PMID 3921074 DOI: 10.1095/Biolreprod32.2.391  0.544
1985 Taché Y, Lesiege D, Vale W, Collu R. Gastric hypersecretion by intracisternal TRH: dissociation from hypophysiotropic activity and role of central catecholamine. European Journal of Pharmacology. 107: 149-55. PMID 3920055 DOI: 10.1016/0014-2999(85)90053-6  0.362
1985 Asa SL, Kovacs K, Thorner MO, Leong DA, Rivier J, Vale W. Immunohistological localization of growth hormone-releasing hormone in human tumors. The Journal of Clinical Endocrinology and Metabolism. 60: 423-427. PMID 3919041 DOI: 10.1210/Jcem-60-3-423  0.323
1985 Birnbaumer L, Shahabi N, Rivier J, Vale W. Evidence for a physiological role of gonadotropin-releasing hormone (GnRH) or GnRH-like material in the ovary. Endocrinology. 116: 1367-70. PMID 3918852 DOI: 10.1210/ENDO-116-4-1367  0.402
1985 Vance ML, Kaiser DL, Evans WS, Thorner MO, Furlanetto R, Rivier J, Vale W, Perisutti G, Frohman LA. Evidence for a limited growth hormone (GH)-releasing hormone (GHRH)-releasable quantity of GH: effects of 6-hour infusions of GHRH on GH secretion in normal man. The Journal of Clinical Endocrinology and Metabolism. 60: 370-5. PMID 3917460 DOI: 10.1210/jcem-60-2-370  0.4
1985 Thorner MO, Reschke J, Chitwood J, Rogol AD, Furlanetto R, Rivier J, Vale W, Blizzard RM. Acceleration of growth in two children treated with human growth hormone-releasing factor. The New England Journal of Medicine. 312: 4-9. PMID 3917299 DOI: 10.1056/NEJM198501033120102  0.352
1985 Kornreich W, Anderson H, Porter J, Vale W, Rivier J. Peptide N-alkylamides by solid phase synthesis. International Journal of Peptide and Protein Research. 25: 414-20. PMID 3894262 DOI: 10.1111/J.1399-3011.1985.Tb02194.X  0.349
1985 Eaves M, Thatcher-Britton K, Rivier J, Vale W, Koob GF. Effects of corticotropin releasing factor on locomotor activity in hypophysectomized rats Peptides. 6: 923-926. PMID 3878503 DOI: 10.1016/0196-9781(85)90323-7  0.448
1985 Seifert H, Chesnut J, Souza ED, Rivier J, Vale W. Binding sites for calcitonin gene-related peptide in distinct areas of rat brain Brain Research. 346: 195-198. PMID 3876866 DOI: 10.1016/0006-8993(85)91116-3  0.308
1985 Agnati LF, Fuxe K, Yu Z, Härfstrand A, Okret S, Wikström A, Goldstein M, Zoli M, Vale W, Gustafsson JA. Morphometrical analysis of the distribution of corticotrophin releasing factor, glucocorticoid receptor and phenylethanolamine-N-methyltransferase immunoreactive structures in the paraventricular hypothalamic nucleus of the rat. Neuroscience Letters. 54: 147-152. PMID 3873028 DOI: 10.1016/S0304-3940(85)80070-7  0.352
1985 Brown MR, Fisher LA, Webb V, Vale WW, Rivier JE. Corticotropin-releasing factor: a physiologic regulator of adrenal epinephrine secretion. Brain Research. 328: 355-7. PMID 3872696 DOI: 10.1016/0006-8993(85)91048-0  0.332
1985 De Souza EB, Insel TR, Perrin MH, Rivier J, Vale WW, Kuhar MJ. Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 3189-203. PMID 3001239 DOI: 10.1523/Jneurosci.05-12-03189.1985  0.369
1985 De Souza EB, Perrin MH, Whitehouse PJ, Rivier J, Vale W, Kuhar MJ. Corticotropin-releasing factor receptors in human pituitary gland: autoradiographic localization. Neuroendocrinology. 40: 419-22. PMID 2989722 DOI: 10.1159/000124107  0.409
1985 Seifert H, Perrin M, Rivier J, Vale W. Growth hormone-releasing factor binding sites in rat anterior pituitary membrane homogenates: modulation by glucocorticoids. Endocrinology. 117: 424-6. PMID 2988927 DOI: 10.1210/ENDO-117-1-424  0.356
1985 Plotsky PM, Bruhn TO, Vale W. Hypophysiotropic regulation of adrenocorticotropin secretion in response to insulin-induced hypoglycemia. Endocrinology. 117: 323-9. PMID 2988921 DOI: 10.1210/endo-117-1-323  0.387
1985 Rivier C, Vale W. Effect of the long-term administration of corticotropin-releasing factor on the pituitary-adrenal and pituitary-gonadal axis in the male rat. The Journal of Clinical Investigation. 75: 689-94. PMID 2982917 DOI: 10.1172/JCI111748  0.592
1985 Seifert H, Perrin M, Rivier J, Vale W. Binding sites for growth hormone releasing factor on rat anterior pituitary cells Nature. 313: 487-489. PMID 2982107 DOI: 10.1038/313487A0  0.48
1985 Plotsky PM, Bruhn TO, Vale W. Evidence for multifactor regulation of the adrenocorticotropin secretory response to hemodynamic stimuli. Endocrinology. 116: 633-9. PMID 2981671 DOI: 10.1210/endo-116-2-633  0.419
1985 Rivier C, Vale W. Involvement of corticotropin-releasing factor and somatostatin in stress-induced inhibition of growth hormone secretion in the rat. Endocrinology. 117: 2478-82. PMID 2866087 DOI: 10.1210/endo-117-6-2478  0.636
1985 Plotsky PM, Vale W. Patterns of growth hormone-releasing factor and somatostatin secretion into the hypophysial-portal circulation of the rat. Science (New York, N.Y.). 230: 461-3. PMID 2864742 DOI: 10.1126/Science.2864742  0.437
1985 Vance ML, Kaiser DL, Evans WS, Furlanetto R, Vale W, Rivier J, Thorner MO. Pulsatile growth hormone secretion in normal man during a continuous 24-hour infusion of human growth hormone releasing factor (1-40). Evidence for intermittent somatostatin secretion. The Journal of Clinical Investigation. 75: 1584-90. PMID 2860126 DOI: 10.1172/JCI111864  0.424
1985 Peterfreund RA, Sawchenko PE, Vale W. Thyroid hormones reversibly suppress somatostatin secretion and immunoreactivity in cultured neocortical cells. Brain Research. 328: 259-70. PMID 2859080 DOI: 10.1016/0006-8993(85)91037-6  0.374
1985 Barinaga M, Bilezikjian LM, Vale WW, Rosenfeld MG, Evans RM. Independent effects of growth hormone releasing factor on growth hormone release and gene transcription. Nature. 314: 279-81. PMID 2858817 DOI: 10.1038/314279A0  0.345
1985 Seifert H, Sawchenko P, Chesnut J, Rivier J, Vale W, Pandol SJ. Receptor for calcitonin gene-related peptide: binding to exocrine pancreas mediates biological actions. The American Journal of Physiology. 249: G147-51. PMID 2409816 DOI: 10.1152/ajpgi.1985.249.1.G147  0.448
1985 Rivier J, Pandol S, Perrin M, Seifert H, Galyean R, Yamamoto G, Rivier C, Vale W. Invited speakers' abstractConformationally altered fragments of rat GRF: VIP homologs, analogs or both? Regulatory Peptides. 10. DOI: 10.1016/0167-0115(85)90297-6  0.518
1984 Rivier C, Vale W. Corticotropin-releasing factor (CRF) acts centrally to inhibit growth hormone secretion in the rat. Endocrinology. 114: 2409-11. PMID 6609812 DOI: 10.1210/endo-114-6-2409  0.629
1984 Sawchenko PE, Swanson LW, Vale WW. Corticotropin-releasing factor: co-expression within distinct subsets of oxytocin-, vasopressin-, and neurotensin-immunoreactive neurons in the hypothalamus of the male rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 1118-29. PMID 6609226 DOI: 10.1523/Jneurosci.04-04-01118.1984  0.348
1984 Pallai PV, Mabilia M, Goodman M, Vale W, Rivier J. Structural homology of corticotropin-releasing factor, sauvagine, and urotensin I: circular dichroism and prediction studies. Proceedings of the National Academy of Sciences of the United States of America. 80: 6770-4. PMID 6606178 DOI: 10.1073/Pnas.80.22.6770  0.33
1984 Sundaram K, Thau RB, Goldstein M, Phillips DM, Rivier J, Vale W, Bardin CW. Effect of an LHRH agonist on pituitary and testicular function in rhesus monkeys Reproduction. 72: 365-371. PMID 6439862 DOI: 10.1530/Jrf.0.0720365  0.387
1984 Williams T, Berelowitz M, Joffe SN, Thorner MO, Rivier J, Vale W, Frohman LA. Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction. The New England Journal of Medicine. 311: 1403-1407. PMID 6436706 DOI: 10.1056/Nejm198411293112203  0.316
1984 Thorner MO, Frohman LA, Leong DA, Thominet J, Downs T, Hellmann P, Chitwood J, Vaughan JM, Vale W. Extrahypothalamic growth-hormone-releasing factor (GRF) secretion is a rare cause of acromegaly: Plasma GRF levels in 177 acromegalic patients Journal of Clinical Endocrinology and Metabolism. 59: 846-849. PMID 6434585 DOI: 10.1210/Jcem-59-5-846  0.32
1984 Evans WS, Borges JL, Vance ML, Kaiser DL, Rogol AD, Furlanetto R, Rivier J, Vale W, Thorner MO. Effects of human pancreatic growth hormone-releasing factor-40 on serum growth hormone, prolactin, luteinizing hormone, follicle-stimulating hormone, and somatomedin-C concentrations in normal women throughout the menstrual cycle. The Journal of Clinical Endocrinology and Metabolism. 59: 1006-10. PMID 6434583 DOI: 10.1210/jcem-59-5-1006  0.383
1984 Peter RE, Nahorniak CS, Vale WW, Rivier JE. Human pancreatic growth hormone-releasing factor (hpGRF) stimulates growth hormone release in goldfish. The Journal of Experimental Zoology. 231: 161-3. PMID 6432938 DOI: 10.1002/JEZ.1402310121  0.31
1984 Bercu BB, Spiliotis BE, Lee BC, Brown TJ, Vale W, Rivier J, Nixon WE, Reid R. Effect of a potent gonadotropin releasing hormone antagonist on pulsatile testosterone and gonadotropin secretion in the male nonhuman primate. Life Sciences. 35: 381-387. PMID 6431214 DOI: 10.1016/0024-3205(84)90648-9  0.402
1984 Press M, Tamborlane WV, Thorner MO, Vale W, Rivier J, Gertner JM, Sherwin RS. Pituitary response to growth hormone-releasing factor in diabetes. Failure of glucose-mediated suppression. Diabetes. 33: 804-6. PMID 6430738 DOI: 10.2337/Diab.33.8.804  0.331
1984 Webb CB, Vance ML, Thorner MO, Perisutti G, Thominet J, Rivier J, Vale W, Frohman LA. Plasma growth hormone responses to constant infusions of human pancreatic growth hormone releasing factor. Intermittent secretion or response attenuation. Journal of Clinical Investigation. 74: 96-103. PMID 6429198 DOI: 10.1172/Jci111424  0.417
1984 Charlesworth MC, Grady RR, Shin L, Vale WW, Rivier C, Rivier J, Schwartz NB. Differential suppression of FSH and LH secretion by follicular fluid in the presence or absence of GnRH. Neuroendocrinology. 38: 199-205. PMID 6425710 DOI: 10.1159/000123891  0.552
1984 Frohman LA, Thominet JL, Webb CB, Vance ML, Uderman H, Rivier J, Vale W, Thorner MO. Metabolic clearance and plasma disappearance rates of human pancreatic tumor growth hormone releasing factor in man. Journal of Clinical Investigation. 73: 1304-1311. PMID 6425363 DOI: 10.1172/Jci111333  0.337
1984 Scanes CG, Carsia RV, Lauterio TJ, Huybrechts L, Rivier J, Vale W. Synthetic human pancreatic growth hormone releasing factor (GRF) stimulates growth hormone secretion in the domestic fowl (gallus domesticus) Life Sciences. 34: 1127-1134. PMID 6423920 DOI: 10.1016/0024-3205(84)90083-3  0.401
1984 MacKenzie DS, Gould DR, Peter RE, Rivier J, Vale WW. Response of superfused goldfish pituitary fragments to mammalian and salmon gonadotropin-releasing hormones Life Sciences. 35: 2019-2026. PMID 6387357 DOI: 10.1016/0024-3205(84)90558-7  0.327
1984 Sundaram K, Schmidt F, Thau RB, Rivier J, Vale W, Bardin CW. Species differences in the sensitivity to the antitesticular effects of [Ac-D-NAL(2)1, 4FD-Phe2, D-Trp3, D-Arg6]-lhrh, a potent LHRH antagonist Contraception. 29: 271-281. PMID 6375958 DOI: 10.1016/S0010-7824(84)80007-4  0.367
1984 Sawchenko PE, Swanson LW, Vale WW. Co-expression of corticotropin-releasing factor and vasopressin immunoreactivity in parvocellular neurosecretory neurons of the adrenalectomized rat. Proceedings of the National Academy of Sciences of the United States of America. 81: 1883-7. PMID 6369332 DOI: 10.1073/Pnas.81.6.1883  0.303
1984 Nemeroff CB, Widerlöv E, Bissette G, Walléus H, Karlsson I, Eklund K, Kilts CD, Loosen PT, Vale W. Elevated concentrations of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients. Science (New York, N.Y.). 226: 1342-4. PMID 6334362 DOI: 10.1126/Science.6334362  0.448
1984 Plotsky PM, Bruhn TO, Vale W. Central modulation of immunoreactive corticotropin-releasing factor secretion by arginine vasopressin. Endocrinology. 115: 1639-41. PMID 6332731 DOI: 10.1210/endo-115-4-1639  0.48
1984 Bruhn TO, Sutton RE, Rivier CL, Vale WW. Corticotropin-releasing factor regulates proopiomelanocortin messenger ribonucleic acid levels in vivo. Neuroendocrinology. 39: 170-5. PMID 6332279  0.553
1984 De Souza EB, Perrin MH, Insel TR, Rivier J, Vale WW, Kuhar MJ. Corticotropin-releasing factor receptors in rat forebrain: autoradiographic identification. Science (New York, N.Y.). 224: 1449-51. PMID 6328656 DOI: 10.1126/Science.6328656  0.438
1984 Carey RM, Varma SK, Drake CR, Thorner MO, Kovacs K, Rivier J, Vale W. Ectopic secretion of corticotropin-releasing factor as a cause of Cushing's syndrome. A clinical, morphologic, and biochemical study. The New England Journal of Medicine. 311: 13-20. PMID 6328303 DOI: 10.1056/Nejm198407053110103  0.429
1984 Rivier J, Rivier C, Vale W. Synthetic competitive antagonists of corticotropin-releasing factor: effect on ACTH secretion in the rat. Science (New York, N.Y.). 224: 889-91. PMID 6326264 DOI: 10.1126/Science.6326264  0.584
1984 De Souza EB, Perrin MH, Rivier J, Vale WW, Kuhar MJ. Corticotropin-releasing factor receptors in rat pituitary gland: autoradiographic localization. Brain Research. 296: 202-7. PMID 6324957 DOI: 10.1016/0006-8993(84)90534-1  0.363
1984 DeBold CR, Sheldon WR, DeCherney GS, Jackson RV, Alexander AN, Vale W, Rivier J, Orth DN. Arginine vasopressin potentiates adrenocorticotropin release induced by ovine corticotropin-releasing factor. Journal of Clinical Investigation. 73: 533-538. PMID 6321557 DOI: 10.1172/Jci111240  0.433
1984 Jackson RV, Decherney GS, Debold CR, Sheldon G, Alexander AN, Rivier J, Vale W, Orth DN. Synthetic ovine corticotropin-releasing hormone: simultaneous release of proopiolipomelanocortin peptides in man. The Journal of Clinical Endocrinology and Metabolism. 58: 740-743. PMID 6321535 DOI: 10.1210/Jcem-58-4-740  0.399
1984 Rivier C, Vale W. Influence of corticotropin-releasing factor on reproductive functions in the rat. Endocrinology. 114: 914-21. PMID 6321146 DOI: 10.1210/endo-114-3-914  0.635
1984 Plotsky PM, Vale W. Hemorrhage-induced secretion of corticotropin-releasing factor-like immunoreactivity into the rat hypophysial portal circulation and its inhibition by glucocorticoids. Endocrinology. 114: 164-9. PMID 6317342 DOI: 10.1210/endo-114-1-164  0.446
1984 Pandol SJ, Seifert H, Thomas MW, Rivier J, Vale W. Growth hormone-releasing factor stimulates pancreatic enzyme secretion Science. 225: 326-328. PMID 6204379 DOI: 10.1126/science.6204379  0.421
1984 Brown MR, Rivier C, Vale W. Central nervous system regulation of adrenocorticotropin secretion: role of somatostatins. Endocrinology. 114: 1546-9. PMID 6143656 DOI: 10.1210/endo-114-5-1546  0.611
1984 Koob GF, Swerdlow N, Seeligson M, Eaves M, Sutton R, Rivier J, Vale W. Effects of alpha-flupenthixol and naloxone on CRF-induced locomotor activation Neuroendocrinology. 39: 450-464. PMID 6096752 DOI: 10.1159/000124021  0.341
1984 Rivier C, Rivier J, Mormede P, Vale W. Studies of the nature of the interaction between vasopressin and corticotropin-releasing factor on adrenocorticotropin release in the rat. Endocrinology. 115: 882-6. PMID 6086290 DOI: 10.1210/endo-115-3-882  0.596
1984 MANSFIELD MJ, BEARDSWORTH DE, LOUGHLIN JS, CRAWFORD JD, BODE HH, RIVIER J, VALE W, KUSHNER DC, CRIGLER JF, CROWLEY WF. Long-Term Treatment of Central Precocious Puberty with a Long-Acting Analogue of Luteinizing Hormone-Releasing Hormone. Effects on Somatic Growth and Skeletal Maturation Obstetrical & Gynecological Survey. 39: 591-592. DOI: 10.1097/00006254-198409000-00017  0.368
1984 DEBOLD CR, DECHERNEY S, JACKSON RV, SHELDON WR, ALEXANDER AN, ISLAND DP, RIVIER J, VALE W, ORTH DN. Effect of Synthetic Ovine Corticotropin-Releasing Factor Obstetrical & Gynecological Survey. 39: 289-290. DOI: 10.1097/00006254-198405000-00014  0.384
1984 RIVIER C, VALE W, RIVIER J. ChemInform Abstract: EFFECTS OF GONADOTROPIN RELEASING HORMONE AGONISTS AND ANTAGONISTS ON REPRODUCTIVE FUNCTIONS Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198415364  0.309
1983 Ehlers CL, Henriksen SJ, Wang M, Rivier J, Vale W, Bloom FE. Corticotropin releasing factor produces increases in brain excitability and convulsive seizures in rats. Brain Research. 278: 332-6. PMID 6605787 DOI: 10.1016/0006-8993(83)90266-4  0.407
1983 Palkovits M, Brownstein MJ, Vale W. Corticotropin releasing factor (CRF) immunoreactivity in hypothalamic and extrahypothalamic nuclei of sheep brain. Neuroendocrinology. 37: 302-5. PMID 6605489 DOI: 10.1159/000123564  0.352
1983 Aldenhoff JB, Gruol DL, Rivier J, Vale W, Siggins GR. Corticotropin releasing factor decreases postburst hyperpolarizations and excites hippocampal neurons. Science (New York, N.Y.). 221: 875-7. PMID 6603658 DOI: 10.1126/Science.6603658  0.339
1983 Rivier J, Spiess J, Vale W. Characterization of rat hypothalamic corticotropin-releasing factor. Proceedings of the National Academy of Sciences of the United States of America. 80: 4851-4855. PMID 6603620 DOI: 10.1073/Pnas.80.15.4851  0.666
1983 Taché Y, Goto Y, Gunion MW, Vale W, River J, Brown M. Inhibition of gastric acid secretion in rats by intracerebral injection of corticotropin-releasing factor. Science (New York, N.Y.). 222: 935-7. PMID 6415815 DOI: 10.1126/SCIENCE.6415815  0.411
1983 Mayo KE, Vale W, Rivier J, Rosenfeld MG, Evans RM. Expression-cloning and sequence of a cDNA encoding human growth hormone-releasing factor Nature. 306: 86-88. PMID 6415488 DOI: 10.1038/306086a0  0.41
1983 Barinaga M, Yamonoto G, Rivier C, Vale W, Evans R, Rosenfeld MG. Transcriptional regulation of growth hormone gene expression by growth hormone-releasing factor. Nature. 306: 84-5. PMID 6415487 DOI: 10.1038/306084A0  0.606
1983 Evans WS, Borges JL, Kaiser DL, Vance ML, Sellers RP, MacLeod RM, Vale W, Rivier J, Thorner MO. Intranasal administration of human pancreatic tumor GH-releasing factor-40 stimulates GH release in normal men. The Journal of Clinical Endocrinology and Metabolism. 57: 1081-3. PMID 6413525 DOI: 10.1210/JCEM-57-5-1081  0.389
1983 Arimura A, Culler MD, Turkelson CM, Luciano MG, Thomas CR, Obara N, Groot K, Rivier J, Vale W. In vitro pituitary hormone releasing activity of 40 residue human pancreatic tumor growth hormone releasing factor. Peptides. 4: 107-10. PMID 6408622 DOI: 10.1016/0196-9781(83)90175-4  0.43
1983 Spiess J, Rivier J, Vale W. Characterization of rat hypothalamic growth hormone-releasing factor. Nature. 303: 532-5. PMID 6406907 DOI: 10.1038/303532a0  0.483
1983 Pineda JL, Lee BC, Spiliotis BE, Vale W, Rivier J, Brown TJ, Bercu BB. EFFECT OF GNRH ANTAGONIST, [Ac-Δ3Pro1, pFDPhe2, DTrp3,6] GNRH, ON PULSATILE GONADOTROPIN SECRETION IN THE CASTRATE MALE PRIMATE The Journal of Clinical Endocrinology and Metabolism. 56: 420-422. PMID 6401754 DOI: 10.1210/Jcem-56-2-420  0.369
1983 Filicori M, Hall DA, Loughlin JS, Rivier J, Vale W, Crowley WF. A conservative approach to the management of uterine leiomyoma: pituitary desensitization by a luteinizing hormone-releasing hormone analogue. American Journal of Obstetrics and Gynecology. 147: 726-7. PMID 6356927 DOI: 10.1016/0002-9378(83)90463-5  0.373
1983 Rivier C, Vale W, Rivier J. Effects of gonadotropin releasing hormone agonists and antagonists on reproductive functions. Journal of Medicinal Chemistry. 26: 1545-50. PMID 6355476 DOI: 10.1021/JM00365A001  0.596
1983 Spiess J, Rivier J, Vale W. Sequence analysis of rat hypothalamic corticotropin-releasing factor with the o-phthalaldehyde strategy. Biochemistry. 22: 4341-4346. PMID 6354254 DOI: 10.1021/Bi00287A027  0.633
1983 Rivier C, Vale W. Influence of ethanol on reproductive functions of the adult male rat as a function of body weight. Alcoholism, Clinical and Experimental Research. 7: 210-2. PMID 6346925 DOI: 10.1111/J.1530-0277.1983.Tb05443.X  0.503
1983 Sherwood N, Eiden L, Brownstein M, Spiess J, Rivier J, Vale W. Characterization of a teleost gonadotropin-releasing hormone. Proceedings of the National Academy of Sciences of the United States of America. 80: 2794-8. PMID 6341999 DOI: 10.1073/Pnas.80.9.2794  0.674
1983 Edwards SA, Trotter J, Rivier J, Vale W. Flow cytometric separation of gonadotrophs from dispersed rat pituitaries using a fluorescent GNRH antagonist Molecular and Cellular Endocrinology. 30: 21-35. PMID 6341116 DOI: 10.1016/0303-7207(83)90198-3  0.357
1983 Vale W, Vaughan J, Yamamoto G, Bruhn T, Douglas C, Dalton D, Rivier C, Rivier J. Assay of corticotropin releasing factor. Methods in Enzymology. 103: 565-77. PMID 6321896 DOI: 10.1016/S0076-6879(83)03040-2  0.561
1983 Rivier C, Vale W. Effect of angiotensin II on ACTH release in vivo: role of corticotropin-releasing factor. Regulatory Peptides. 7: 253-8. PMID 6320315 DOI: 10.1016/0167-0115(83)90018-6  0.566
1983 Rivier C, Rivier J, Perrin M, Vale W. Comparison of the effect of several gonadotropin releasing hormone antagonists on luteinizing hormone secretion, receptor binding and ovulation. Biology of Reproduction. 29: 374-8. PMID 6315093 DOI: 10.1095/Biolreprod29.2.374  0.645
1983 Vale W, Rivier C, Brown MR, Spiess J, Koob G, Swanson L, Bilezikjian L, Bloom F, Rivier J. Chemical and biological characterization of corticotropin releasing factor. Recent Progress in Hormone Research. 39: 245-70. PMID 6314446 DOI: 10.1016/B978-0-12-571139-5.50010-0  0.601
1983 Rivier C, Vale W. Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin. Nature. 305: 325-7. PMID 6312319 DOI: 10.1038/305325a0  0.6
1983 Liu JH, Muse K, Contreras P, Gibbs D, Vale W, Rivier J, Yen SSC. Augmentation Of Acth-Releasing Activity Op Synthetic Corticotropin Releasing Factor (Crf) By Vasopressin In Women The Journal of Clinical Endocrinology and Metabolism. 57: 1087-1089. PMID 6311862 DOI: 10.1210/Jcem-57-5-1087  0.431
1983 Rivier C, Vale W. Influence of the frequency of ovine corticotropin-releasing factor administration on adrenocorticotropin and corticosterone secretion in the rat. Endocrinology. 113: 1422-6. PMID 6311521 DOI: 10.1210/endo-113-4-1422  0.626
1983 Sirinathsinghji DJS, Rees LH, Rivier J, Vale W. Corticotropin-releasing factor is a potent inhibitor of sexual receptivity in the female rat Nature. 305: 232-235. PMID 6310414 DOI: 10.1038/305232A0  0.446
1983 Rivier C, Vale W. Interaction of corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin secretion in vivo. Endocrinology. 113: 939-42. PMID 6307672 DOI: 10.1210/endo-113-3-939  0.634
1983 Donald RA, Redekopp C, Cameron V, Nicholls MG, Bolton J, Livesey J, Espiner EA, Rivier J, Vale W. The hormonal actions of corticotropin-releasing factor in sheep: Effect of intravenous and intracerebroventricular injection Endocrinology. 113: 866-870. PMID 6307669 DOI: 10.1210/Endo-113-3-866  0.442
1983 Vale W, Vaughan J, Smith M, Yamamoto G, Rivier J, Rivier C. Effects of synthetic ovine corticotropin-releasing factor, glucocorticoids, catecholamines, neurohypophysial peptides, and other substances on cultured corticotropic cells. Endocrinology. 113: 1121-31. PMID 6307665 DOI: 10.1210/endo-113-3-1121  0.601
1983 Debold CR, Decherney GS, Jackson RV, Sheldon WR, Alexander AN, Island DP, Rivier J, Vale W, Orth DN. Effect of Synthetic Ovine Corticotropin-Releasing Factor: Prolonged Duration of Action and Biphasic Response of Plasma Adrenocorticotropin and Cortisol* The Journal of Clinical Endocrinology and Metabolism. 57: 294-298. PMID 6306038 DOI: 10.1210/Jcem-57-2-294  0.359
1983 Smith MA, Perrin MH, Vale WW. Desensitization of cultured pituitary cells to gonadotropin-releasing hormone: evidence for a post-receptor mechanism. Molecular and Cellular Endocrinology. 30: 85-96. PMID 6301908 DOI: 10.1016/0303-7207(83)90203-4  0.346
1983 Rivier C, Rivier J, Lederis K, Vale W. In vitro and in vivo ACTH-releasing activity of ovine CRF, sauvagine and urotensin I. Regulatory Peptides. 5: 139-43. PMID 6298906 DOI: 10.1016/0167-0115(83)90121-0  0.613
1983 Orth DN, Jackson RV, DeCherney GS, DeBold CR, Alexander AN, Island DP, Rivier J, Rivier C, Spiess J, Vale W. Effect of synthetic ovine corticotropin-releasing factor. Dose response of plasma adrenocorticotropin and cortisol. The Journal of Clinical Investigation. 71: 587-95. PMID 6298280 DOI: 10.1172/Jci110804  0.567
1983 Rivier J, Spiess J, Thorner M, Vale W. Characterization of a growth hormone-releasing factor from a human pancreatic islet tumour. Nature. 300: 276-8. PMID 6292724 DOI: 10.1038/300276A0  0.433
1983 Wang N-, Sundaram K, Pavlou S, Rivier J, Vale W, Bardin CW. Mice are insensitive to the antitesticular effects of luteinizing hormone-releasing hormone agonists. Endocrinology. 112: 331-335. PMID 6291919 DOI: 10.1210/Endo-112-1-331  0.442
1983 Smith MA, Perrin MH, Vale WW. Interaction of adenosine 3',5'-monophosphate derivatives with the gonadotropin-releasing hormone receptor on pituitary and ovary. Endocrinology. 111: 1951-7. PMID 6291903 DOI: 10.1210/ENDO-111-6-1951  0.312
1983 Bilezikjian LM, Vale WW. Stimulation of adenosine 3',5'-monophosphate production by growth hormone-releasing factor and its inhibition by somatostatin in anterior pituitary cells in vitro. Endocrinology. 113: 1726-31. PMID 6194979 DOI: 10.1210/ENDO-113-5-1726  0.321
1983 Bilezikjian LM, Vale WW. Glucocorticoids inhibit corticotropin-releasing factor-induced production of adenosine 3',5'-monophosphate in cultured anterior pituitary cells. Endocrinology. 113: 657-62. PMID 6191964 DOI: 10.1210/ENDO-113-2-657  0.313
1983 Borges JL, Blizzard RM, Gelato MC, Furlanetto R, Rogol AD, Evans WS, Vance ML, Kaiser DL, MacLeod RM, Merriam GR, Loriaux DL, Spiess J, Rivier J, Vale W, Thorner MO. Effects of human pancreatic tumour growth hormone releasing factor on growth hormone and somatomedin C levels in patients with idiopathic growth hormone deficiency. Lancet (London, England). 2: 119-24. PMID 6134978 DOI: 10.1016/S0140-6736(83)90113-7  0.638
1983 Rosenthal LE, Yamashiro DJ, Rivier J, Vale W, Brown M, Dharmsathaphorn K. Structure-Activity Relationships of Somatostatin Analogs in the Rabbit Ileum and the Rat Colon Journal of Clinical Investigation. 71: 840-849. PMID 6131906 DOI: 10.1172/Jci110838  0.359
1983 Vale W, Vaughan J, Yamamoto G, Spiess J, Rivier J. Effects Of Synthetic Human Pancreatic (Tumor) Gh Releasing Factor And Somatostatin, Triiodothyronine And Dexamethasone On Gh Secretion In Vitro Endocrinology. 112: 1553-1555. PMID 6131812 DOI: 10.1210/Endo-112-4-1553  0.436
1983 Spiess Y, Smith MA, Vale W. Superfusion of dissociated pancreatic islet cells attached to Cytodex beads. Diabetes. 31: 189-93. PMID 6130017 DOI: 10.2337/diab.31.3.189  0.332
1983 Vale W, Rivier C, Brown M, Plotsky P, Swanson L, Bruhn T, Bloom F, Koob G, Spiess J, Thorner M, Rivier. J. CHARACTERIZATION OF CORTICOTROPIN AND GROWTH HORMONE RELEASING FACTOR. Acta Endocrinologica. 104: S10. DOI: 10.1530/acta.0.103s010  0.401
1983 Antoni FA, Palkovits M, Makara GB, Linton EA, Lowry PJ, Kiss JZ, Bugajski J, Gą A, dek, Walker RF, Luine VN, McEwen BS, Wehrenberg WB, Brazeau P, Luben R, ... ... Vale W, et al. Subject Index Vol. 36, 1983 Neuroendocrinology. 36: 495-496. DOI: 10.1159/000123507  0.48
1983 Antoni FA, Palkovits M, Makara GB, Linton EA, Lowry PJ, Kiss JZ, Bugajski J, Gą A, dek, Walker RF, Luine VN, McEwen BS, Wehrenberg WB, Brazeau P, Luben R, ... ... Vale W, et al. Contents, Vol. 36, 1983 Neuroendocrinology. 36. DOI: 10.1159/000123490  0.489
1982 Brown MR, Fisher LA, Spiess J, Rivier C, Rivier J, Vale W. Corticotropin-releasing factor: actions on the sympathetic nervous system and metabolism. Endocrinology. 111: 928-31. PMID 7049676 DOI: 10.1210/endo-111-3-928  0.595
1982 Rivier C, Vale W. Interaction of gonadotropin-releasing hormone agonist and antagonist with progesterone, prolactin, or human chorionic gonadotropin during pregnancy in the rat. Endocrinology. 110: 347-51. PMID 7035139 DOI: 10.1210/endo-110-2-347  0.608
1982 Lecomte P, Wang N-, Sundaram K, Rivier J, Vale W, Bardin CW. The Antiandrogenic Action of Gonadotropin-Releasing Hormone and Its Agonists on the Mouse Kidney Endocrinology. 110: 1-6. PMID 7032892 DOI: 10.1210/Endo-110-1-1  0.364
1982 Rivier J, Rivier C, Spiess J, Vale W. High-performance liquid chromatographic purification of peptide hormones: ovine hypothalamic amunine (corticotropin releasing factor). Analytical Biochemistry. 127: 258-66. PMID 6984596 DOI: 10.1016/0003-2697(82)90170-1  0.573
1982 Sutton RE, Koob GF, Le Moal M, Rivier J, Vale W. Corticotropin releasing factor produces behavioural activation in rats. Nature. 297: 331-3. PMID 6978997 DOI: 10.1038/297331a0  0.426
1982 Fisher LA, Rivier J, Rivier C, Spiess J, Vale W, Brown MR. Corticotropin-releasing factor (CRF): central effects on mean arterial pressure and heart rate in rats. Endocrinology. 110: 2222-4. PMID 6978810 DOI: 10.1210/endo-110-6-2222  0.563
1982 Brown MR, Fisher LA, Rivier J, Spiess J, Rivier C, Vale W. Corticotropin-releasing factor: effects on the sympathetic nervous system and oxygen consumption. Life Sciences. 30: 207-10. PMID 6976501 DOI: 10.1016/0024-3205(82)90654-3  0.559
1982 McCreery BR, Licht P, Barnes R, Rivier JE, Vale WW. Actions of agonistic and antagonistic analogs of gonadotropin releasing hormone (Gn-RH) in the bullfrog Rana catesbeiana. General and Comparative Endocrinology. 46: 511-20. PMID 6807746 DOI: 10.1016/0016-6480(82)90107-1  0.3
1982 Bloom FE, Battenberg EL, Rivier J, Vale W. Corticotropin releasing factor (CRF): immunoreactive neurones and fibers in rat hypothalamus. Regulatory Peptides. 4: 43-8. PMID 6750704 DOI: 10.1016/0167-0115(82)90107-0  0.317
1982 Spiess J, Rivier J, Thorner M, Vale W. Sequence analysis of a growth hormone releasing factor from a human pancreatic islet tumor Biochemistry. 21: 6037-6040. PMID 6295453 DOI: 10.1021/Bi00267A002  0.643
1982 Thorner MO, Perryman RL, Cronin MJ, Rogol AD, Draznin M, Johanson A, Vale W, Horvath E, Kovacs K. Somatotroph hyperplasia. Successful treatment of acromegaly by removal of a pancreatic islet tumor secreting a growth hormone-releasing factor. The Journal of Clinical Investigation. 70: 965-77. PMID 6290540 DOI: 10.1172/Jci110708  0.388
1982 Gibbs DM, Stewart RD, Liu JH, Vale W, Rivier J, Yen SSC. Effects of Synthetic Corticotropin-Releasing Factor and Dopamine on the Release of Immunoreactive β-Endorphin/β-Lipotropin and α-Melanocyte-Stimulating Hormone from Human Fetal Pituitaries in Vitro* The Journal of Clinical Endocrinology and Metabolism. 55: 1149-1152. PMID 6290522 DOI: 10.1210/Jcem-55-6-1149  0.41
1982 Rivier C, Rivier J, Vale W. Inhibition of adrenocorticotropic hormone secretion in the rat by immunoneutralization of corticotropin-releasing factor. Science (New York, N.Y.). 218: 377-9. PMID 6289439 DOI: 10.1126/Science.6289439  0.64
1982 Brown MR, Fisher LA, Spiess J, Rivier J, Rivier C, Vale W. Comparison of the biologic actions of corticotropin-releasing factor and sauvagine. Regulatory Peptides. 4: 107-14. PMID 6289384 DOI: 10.1016/0167-0115(82)90101-X  0.574
1982 Doehmer J, Barinaga M, Vale W, Rosenfeld MG, Verma IM, Evans RM. Introduction of rat growth hormone gene into mouse fibroblasts via a retroviral DNA vector: expression and regulation. Proceedings of the National Academy of Sciences of the United States of America. 79: 2268-72. PMID 6285377 DOI: 10.1073/Pnas.79.7.2268  0.365
1982 Britton DR, Rivier C, Shier T, Bloom F, Vale W. In vivo and in vitro effects of tetrahydroisoquinolines and other alkaloids on rat pituitary function. Biochemical Pharmacology. 31: 1205-11. PMID 6284172 DOI: 10.1016/0006-2952(82)90005-3  0.569
1982 Rivier C, Brownstein M, Spiess J, Rivier J, Vale W. In vivo corticotropin-releasing factor-induced secretion of adrenocorticotropin, beta-endorphin, and corticosterone. Endocrinology. 110: 272-8. PMID 6274623 DOI: 10.1210/endo-110-1-272  0.627
1982 Reubi JC, Perrin M, Rivier J, Vale W. Pituitary somatostatin receptors: dissociation at the pituitary level of receptor affinity and biological activity for selective somatostatin analogs. Regulatory Peptides. 4: 141-6. PMID 6127756 DOI: 10.1016/0167-0115(82)90081-7  0.363
1982 Reubi JC, Perrin M, Rivier J, Vale W. High affinity binding sites for somatostatin to rat pituitary. Biochemical and Biophysical Research Communications. 105: 1538-45. PMID 6125148 DOI: 10.1016/0006-291X(82)90963-9  0.337
1982 Taché Y, Vale W, Rivier J, Brown M. Brain regulation of gastric acid secretion in rats by neurogastrointestinal peptides. Peptides. 51-5. PMID 6123991 DOI: 10.1016/0196-9781(81)90010-3  0.318
1982 Reubi JC, Rivier J, Perrin M, Brown M, Vale W. Specific high affinity binding sites for somatostatin-28 on pancreatic beta-cells: differences with brain somatostatin receptors. Endocrinology. 110: 1049-51. PMID 6120075 DOI: 10.1210/ENDO-110-3-1049  0.31
1982 Linde R, Doelle GC, Alexander N, Kirchner F, Vale W, Rivier J, Rabin D. Reversible Inhibition of Testicular Steroidogenesis and Spermatogenesis by a Potent Gonadotropin-Releasing Hormone Agonist in Normal Men. An Approach Toward the Development of a Male Contraceptive The Journal of Urology. 127: 839-839. DOI: 10.1016/S0022-5347(17)54090-2  0.387
1981 Spiess J, Villarreal J, Vale W. Isolation and sequence analysis of a somatostatin-like polypeptide from ovine hypothalamus. Biochemistry. 20: 1982-1988. PMID 7225368 DOI: 10.1021/Bi00510A038  0.623
1981 Rivier C, Rivier J, Vale W. Effect of a potent GnRH antagonist and testosterone propionate on mating behavior and fertility in the male rat. Endocrinology. 108: 1998-2001. PMID 7215310 DOI: 10.1210/endo-108-5-1998  0.526
1981 Rivier C, Vale W. Temporal relationship between the abortifacient effects of GnRH antagonists and hormonal secretion. Biology of Reproduction. 24: 1061-7. PMID 7023552 DOI: 10.1095/Biolreprod24.5.1061  0.576
1981 Rivier C, Rivier J, Vale W. Antireproductive effects of a potent GnRH antagonist in the female rat. Endocrinology. 108: 1425-30. PMID 7009151 DOI: 10.1210/endo-108-4-1425  0.592
1981 Lindner J, McNEIL LW, Marney S, Conway M, Rivier J, Vale W, Rabin D. Characterization of human anti-luteinizing hormone-releasing hormone (LRH) antibodies in the serum of a patient with isolated gonadotropin deficiency treated with synthetic LRH. The Journal of Clinical Endocrinology and Metabolism. 52: 267-270. PMID 7007403 DOI: 10.1210/Jcem-52-2-267  0.31
1981 Smith MA, Vale WW. Desensitization to gonadotropin-releasing hormone observed in superfused pituitary cells on Cytodex beads. Endocrinology. 108: 752-9. PMID 7007026 DOI: 10.1210/ENDO-108-3-752  0.352
1981 Taché Y, Vale W, Brown M. Thyrotropin-releasing hormone--CNS action to stimulate gastric acid secretion. Nature. 287: 149-51. PMID 6776408 DOI: 10.1038/287149A0  0.341
1981 Spiess J, Rivier J, Rivier C, Vale W. Primary structure of corticotropin-releasing factor from ovine hypothalamus. Proceedings of the National Academy of Sciences of the United States of America. 78: 6517-21. PMID 6273874 DOI: 10.1073/Pnas.78.10.6517  0.712
1981 Rivier C, Vale W. Interaction of GnRH agonists, pituitary hormones and corticosteroids on progesterone secretion in the male rat. Life Sciences. 29: 1523-9. PMID 6272044 DOI: 10.1016/0024-3205(81)90252-6  0.626
1981 Vale W, Spiess J, Rivier C, Rivier J. Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin. Science (New York, N.Y.). 213: 1394-7. PMID 6267699 DOI: 10.1097/00006254-198205000-00013  0.696
1981 Linde R, Doelle GC, Alexander N, Kirchner F, Vale W, Rivier J, Rabin D. Reversible inhibition of testicular steroidogenesis and spermatogenesis by a potent gonadotropin-releasing hormone agonist in normal men: an approach toward the development of a male contraceptive. The New England Journal of Medicine. 305: 663-667. PMID 6267464 DOI: 10.1056/Nejm198109173051203  0.344
1981 Taché Y, Vale W, Rivier J, Brown M. Brain regulation of gastric secretion: influence of neuropeptides. Proceedings of the National Academy of Sciences of the United States of America. 77: 5515-9. PMID 6159649 DOI: 10.1073/PNAS.77.9.5515  0.355
1981 Smith MA, Vale WW. Superfusion of rat anterior pituitary cells attached to Cytodex beads: validation of a technique. Endocrinology. 107: 1425-31. PMID 6159198 DOI: 10.1210/ENDO-107-5-1425  0.354
1981 Adrian TE, Barnes AJ, Long RG, O'Shaughnessy DJ, Brown MR, Rivier J, Vale W, Blackburn AM, Bloom SR. The effect of somatostatin analogs on secretion of growth, pancreatic, and gastrointestinal hormones in man. The Journal of Clinical Endocrinology and Metabolism. 53: 675-81. PMID 6116721 DOI: 10.1210/jcem-53-4-675  0.347
1981 Barnes AJ, Long RG, Adrian TE, Vale W, Brown MR, Rivier JE, Hanley J, Ghatei MA, Sarson DL, Bloom SR. Effect of a long-acting octapeptide analogue of somatostatin on growth hormone and pancreatic and gastrointestinal hormones in man. Clinical Science (London, England : 1979). 61: 653-6. PMID 6116553 DOI: 10.1042/Cs0610653  0.382
1981 Taché Y, Rivier J, Vale W, Brown M. Is somatostatin or a somatostatin-like peptide involved in central nervous system control of gastric secretion? Regulatory Peptides. 1: 307-15. PMID 6114519 DOI: 10.1016/0167-0115(81)90054-9  0.326
1981 Reubi JC, Perrin MH, Rivier JE, Vale W. High affinity binding sites for a somatostatin-28 analog in rat brain. Life Sciences. 28: 2191-8. PMID 6114372 DOI: 10.1016/0024-3205(81)90628-7  0.317
1981 Brown M, Rivier J, Vale W. Somatostatin-28: selective action on the pancreatic beta-cell and brain. Endocrinology. 108: 2391-6. PMID 6112138 DOI: 10.1210/ENDO-108-6-2391  0.331
1981 Taché Y, Marki W, Rivier J, Vale W, Brown M. Central Nervous System Inhibition of Gastric Secretion in the Rat by GastrinReleasing Peptide, a Mammalian Bombesin Gastroenterology. 81: 298-302. DOI: 10.1016/S0016-5085(81)80061-3  0.402
1980 Rivier C, Rivier J, Vale W. Antireproductive effects of a potent gonadotropin-releasing hormone antagonist in the male rat. Science (New York, N.Y.). 210: 93-5. PMID 6774418 DOI: 10.1126/Science.6774418  0.606
1980 Nemeroff CB, Bissette G, Martin JB, Brazeau P, Vale W, Kizer JS, Prange AJ. Effect of chronic treatment with thyrotropin-releasing hormone (TRH) or an analog of TRH (linear beta-alanine TRH) on the hypothalamic-pituitary-thyroid axis. Neuroendocrinology. 30: 193-9. PMID 6769064 DOI: 10.1159/000123000  0.414
1980 Crowley WF, Beitins IZ, Vale W, Kliman B, Rivier J, Rivier C, McArthur JW. The biologic activity of a potent analogue of gonadotropin-releasing hormone in normal and hypogonadotropic men. The New England Journal of Medicine. 302: 1052-7. PMID 6767977 DOI: 10.1056/NEJM198005083021903  0.59
1980 Palkovits M, Kobayashi RM, Brown M, Vale W. Changes in hypothalamic, limbic and extrapyramidal somatostatin levels following various hypothalamic transections in rat Brain Research. 195: 499-505. PMID 6105007 DOI: 10.1016/0006-8993(80)90088-8  0.349
1980 Spiess J, Vale W. Multiple forms of somatostatin-like activity in rat hypothalamus. Biochemistry. 19: 2861-2866. PMID 6104982 DOI: 10.1021/Bi00554A007  0.612
1980 Taché Y, Märki W, Rivier J, Vale W, Brown M. Gastrin releasing peptide (GRP): Central nervous system (CNS) action to inhibit gastric secretion in rats Regulatory Peptides. 1. DOI: 10.1016/0167-0115(80)90242-6  0.388
1979 Brown M, Rivier J, Vale W. Somatostatin: central nervous system actions on glucoregulation. Endocrinology. 104: 1709-15. PMID 446391 DOI: 10.1210/ENDO-104-6-1709  0.308
1979 Ipp E, Rivier J, Dobbs RE, Brown M, Vale W, Unger RH. Somatostatin analogs inhibit somatostatin release. Endocrinology. 104: 1270-1273. PMID 436775 DOI: 10.1210/Endo-104-5-1270  0.371
1979 Rivier C, Vale W. Hormonal secretion in male rats chronically treated with [D-Trp6, Pro9-NEt]-LRF. Life Sciences. 25: 1065-74. PMID 390282 DOI: 10.1016/0024-3205(79)90592-7  0.57
1979 Rivier C, Rivier J, Vale W. Chronic effects of [D-Trp6,Pro9-NEt]luteinizing hormone-releasing factor on reproductive processes in the male rat. Endocrinology. 105: 1191-201. PMID 385303 DOI: 10.1210/endo-105-5-1191  0.521
1979 Rivier C, Rivier J, Vale W. Effect of the LRF-antagonist [D-pGlu1, D-Phe2, D-Trp3,6]-LRF on pregnancy in the rat. Contraception. 19: 185-90. PMID 371912 DOI: 10.1016/S0010-7824(79)80030-X  0.47
1979 Spiess J, Rivier JE, Rodkey JA, Bennett CD, Vale W. Isolation and characterization of somatostatin from pigeon pancreas Proceedings of the National Academy of Sciences of the United States of America. 76: 2974-2978. PMID 288081 DOI: 10.1073/Pnas.76.6.2974  0.587
1979 Long RG, Barnes AJ, Adrian TE, Mallinson CN, Brown MR, Vale W, Rivier JE, Christofides ND, Bloom SR. Suppression of pancreatic endocrine tumour secretion by long-acting somatostatin analogue. Lancet (London, England). 2: 764-7. PMID 90860 DOI: 10.1016/S0140-6736(79)92115-9  0.359
1979 Brown M, Allen R, Villarreal J, Rivier J, Vale W. Bombesin-like activity: radioimmunologic assessment in biological tissues. Life Sciences. 23: 2721-8. PMID 84318 DOI: 10.1016/0024-3205(78)90652-5  0.332
1979 Long RG, Adrian TE, Barnes AJ, Bloom SR, Brown MR, Vale W, Rivier JE. Effect of Analogues of Somatostatin on Pancreatic and Gut Hormones and Growth Hormone in Man Clinical Science. 57. DOI: 10.1042/Cs057023Pb  0.363
1978 Vale W, Rivier C, Brown M, Leppaluoto J, Ling N, Monahan M, Rivier J. Pharmacology of hypothalamic regulatory peptides. Clinical Endocrinology. 261S-273S. PMID 829923 DOI: 10.1111/j.1365-2265.1976.tb03834.x  0.505
1978 Rivier C, Rivier J, Vale W. The effect of bombesin and related peptides on prolactin and growth hormone secretion in the rat Endocrinology. 102: 519-522. PMID 743973 DOI: 10.1210/Endo-102-2-519  0.612
1978 Brown M, Rivier J, Vale W. Somatostatin: central nervous system (CNS) action on glucoregulation. Metabolism: Clinical and Experimental. 27: 1253-6. PMID 682989 DOI: 10.1016/0026-0495(78)90054-9  0.373
1978 Iversen LL, Iversen SD, Bloom F, Douglas C, Brown M, Vale W. Calcium-dependent release of somatostatin and neurotensin from rat brain in vitro. Nature. 273: 161-3. PMID 643079 DOI: 10.1038/273161a0  0.408
1978 Rivier C, Rivier J, Vale W. Chronic effects of [D-Trp6-Pro9-NEt]luteinizing hormone-releasing factor on reproductive processes in the female rat. Endocrinology. 103: 2299-305. PMID 371955 DOI: 10.1210/endo-103-6-2299  0.564
1978 Vale W, Rivier C, Yang L, Minick S, Guillemin R. Effects of purified hypothalamic corticotropin-releasing factor and other substances on the secretion of adrenocorticotropin and beta-endorphin-like immunoactivities in vitro. Endocrinology. 103: 1910-5. PMID 218793 DOI: 10.1210/endo-103-5-1910  0.675
1978 Vale W, Rivier J, Ling N, Brown M. Biologic and immunologic activities and applications of somatostatin analogs. Metabolism: Clinical and Experimental. 27: 1391-401. PMID 210361 DOI: 10.1016/0026-0495(78)90081-1  0.341
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