Robert M. Grainger - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Genetics, Neuroscience Biology

82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Louie SH, Fisher M, Grainger RM. Elucidating the framework for specification and determination of the embryonic retina. Experimental Cell Research. 112316. PMID 33031807 DOI: 10.1016/j.yexcr.2020.112316  0.312
2020 Nakayama T, Grainger RM, Cha SW. Simple embryo injection of long single-stranded donor templates with the CRISPR/Cas9 system leads to homology-directed repair in Xenopus tropicalis and Xenopus laevis. Genesis (New York, N.Y. : 2000). e23366. PMID 32277804 DOI: 10.1002/Dvg.23366  0.396
2019 Fisher M, Grainger RM. Special Considerations for Making Explants and Transplants with . Cold Spring Harbor Protocols. PMID 31010887 DOI: 10.1101/Pdb.Prot097428  0.362
2016 Nakayama T, Nakajima K, Cox A, Fisher M, Howell M, Fish MB, Yaoita Y, Grainger RM. no privacy, a Xenopus tropicalis mutant, is a model of human Hermansky-Pudlak Syndrome and allows visualization of internal organogenesis during tadpole development. Developmental Biology. PMID 27595926 DOI: 10.1016/J.Ydbio.2016.08.020  0.435
2016 Plautz CZ, Williams HC, Grainger RM. Functional Cloning Using a Xenopus Oocyte Expression System. Journal of Visualized Experiments : Jove. PMID 26862700 DOI: 10.3791/53518  0.456
2015 Nakayama T, Fisher M, Nakajima K, Odeleye AO, Zimmerman KB, Fish MB, Yaoita Y, Chojnowski JL, Lauderdale JD, Netland PA, Grainger RM. Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients. Developmental Biology. PMID 25724657 DOI: 10.1016/J.Ydbio.2015.02.012  0.408
2014 Nakayama T, Blitz IL, Fish MB, Odeleye AO, Manohar S, Cho KW, Grainger RM. Cas9-based genome editing in Xenopus tropicalis. Methods in Enzymology. 546: 355-75. PMID 25398349 DOI: 10.1016/B978-0-12-801185-0.00017-9  0.308
2014 Plautz CZ, Zirkle BE, Deshotel MJ, Grainger RM. Early stages of induction of anterior head ectodermal properties in Xenopus embryos are mediated by transcriptional cofactor ldb1. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 1606-18. PMID 25258326 DOI: 10.1002/Dvdy.24193  0.411
2014 Fish MB, Nakayama T, Fisher M, Hirsch N, Cox A, Reeder R, Carruthers S, Hall A, Stemple DL, Grainger RM. Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character. Developmental Biology. 395: 317-30. PMID 25224223 DOI: 10.1016/J.Ydbio.2014.09.004  0.41
2013 Bhatia S, Bengani H, Fish M, Brown A, Divizia MT, de Marco R, Damante G, Grainger R, van Heyningen V, Kleinjan DA. Disruption of autoregulatory feedback by a mutation in a remote, ultraconserved PAX6 enhancer causes aniridia. American Journal of Human Genetics. 93: 1126-34. PMID 24290376 DOI: 10.1016/J.Ajhg.2013.10.028  0.342
2013 Nakayama T, Fish MB, Fisher M, Oomen-Hajagos J, Thomsen GH, Grainger RM. Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis. Genesis (New York, N.Y. : 2000). 51: 835-43. PMID 24123613 DOI: 10.1002/Dvg.22720  0.346
2012 Ogino H, Ochi H, Uchiyama C, Louie S, Grainger RM. Comparative genomics-based identification and analysis of cis-regulatory elements. Methods in Molecular Biology (Clifton, N.J.). 917: 245-63. PMID 22956093 DOI: 10.1007/978-1-61779-992-1_15  0.337
2012 Grainger RM. Xenopus tropicalis as a model organism for genetics and genomics: past, present, and future. Methods in Molecular Biology (Clifton, N.J.). 917: 3-15. PMID 22956079 DOI: 10.1007/978-1-61779-992-1_1  0.36
2012 Jin H, Fisher M, Grainger RM. Defining progressive stages in the commitment process leading to embryonic lens formation. Genesis (New York, N.Y. : 2000). 50: 728-40. PMID 22566346 DOI: 10.1002/Dvg.22038  0.469
2012 Pearl EJ, Grainger RM, Guille M, Horb ME. Development of Xenopus resource centers: the National Xenopus Resource and the European Xenopus Resource Center. Genesis (New York, N.Y. : 2000). 50: 155-63. PMID 22253050 DOI: 10.1002/Dvg.22013  0.315
2012 Wei S, Xu G, Bridges LC, Williams P, Nakayama T, Shah A, Grainger RM, White JM, DeSimone DW. Roles of ADAM13-regulated Wnt activity in early Xenopus eye development. Developmental Biology. 363: 147-54. PMID 22227340 DOI: 10.1016/J.Ydbio.2011.12.031  0.352
2012 Fish MB, Nakayama T, Grainger RM. Simple, fast, tissue-specific bacterial artificial chromosome transgenesis in Xenopus. Genesis (New York, N.Y. : 2000). 50: 307-15. PMID 22084035 DOI: 10.1002/Dvg.20819  0.442
2011 Harland RM, Grainger RM. Xenopus research: metamorphosed by genetics and genomics. Trends in Genetics : Tig. 27: 507-15. PMID 21963197 DOI: 10.1016/J.Tig.2011.08.003  0.379
2010 Sive HL, Grainger RM, Harland RM. Microinjection of RNA and preparation of secreted proteins from Xenopus oocytes. Cold Spring Harbor Protocols. 2010: pdb.prot5538. PMID 21123425 DOI: 10.1101/Pdb.Prot5538  0.338
2010 Sive HL, Grainger RM, Harland RM. Calibration of the injection volume for microinjection of Xenopus oocytes and embryos. Cold Spring Harbor Protocols. 2010: pdb.prot5537. PMID 21123424 DOI: 10.1101/Pdb.Prot5537  0.354
2010 Sive HL, Grainger RM, Harland RM. Microinjection of Xenopus oocytes. Cold Spring Harbor Protocols. 2010: pdb.prot5536. PMID 21123423 DOI: 10.1101/Pdb.Prot5536  0.316
2010 Sive HL, Grainger RM, Harland RM. Defolliculation of Xenopus oocytes. Cold Spring Harbor Protocols. 2010: pdb.prot5535. PMID 21123422 DOI: 10.1101/Pdb.Prot5535  0.32
2010 Sive HL, Grainger RM, Harland RM. Microinjection of Xenopus embryos. Cold Spring Harbor Protocols. 2010: pdb.ip81. PMID 21123415 DOI: 10.1101/Pdb.Ip81  0.382
2010 Hellsten U, Harland RM, Gilchrist MJ, Hendrix D, Jurka J, Kapitonov V, Ovcharenko I, Putnam NH, Shu S, Taher L, Blitz IL, Blumberg B, Dichmann DS, Dubchak I, Amaya E, ... ... Grainger R, et al. The genome of the Western clawed frog Xenopus tropicalis. Science (New York, N.Y.). 328: 633-6. PMID 20431018 DOI: 10.1126/Science.1183670  0.315
2008 Ogino H, Fisher M, Grainger RM. Convergence of a head-field selector Otx2 and Notch signaling: a mechanism for lens specification. Development (Cambridge, England). 135: 249-58. PMID 18057103 DOI: 10.1242/Dev.009548  0.404
2007 Sive HL, Grainger RM, Harland RM. Synthesis and purification of digoxigenin-labeled RNA probes for in situ hybridization. Csh Protocols. 2007: pdb.prot4778. PMID 21357143 DOI: 10.1101/Pdb.Prot4778  0.382
2007 Sive HL, Grainger RM, Harland RM. Baskets for in situ hybridization and immunohistochemistry. Csh Protocols. 2007: pdb.prot4777. PMID 21357142 DOI: 10.1101/Pdb.Prot4777  0.302
2007 Sive HL, Grainger RM, Harland RM. Microdissection: Explant and Transplant Assays in Xenopus laevis. Csh Protocols. 2007: pdb.top10. PMID 21357111 DOI: 10.1101/Pdb.Top10  0.332
2007 Sive HL, Grainger RM, Harland RM. Dissection of Tightly Adhering Xenopus laevis Tissues by Trypsin Treatment. Csh Protocols. 2007: pdb.prot4752. PMID 21357100 DOI: 10.1101/Pdb.Prot4752  0.411
2007 Sive HL, Grainger RM, Harland RM. Transplantation of Xenopus laevis Lens Ectoderm. Csh Protocols. 2007: pdb.prot4751. PMID 21357099 DOI: 10.1101/Pdb.Prot4751  0.402
2007 Sive HL, Grainger RM, Harland RM. Xenopus laevis Einstecks. Csh Protocols. 2007: pdb.prot4750. PMID 21357098 DOI: 10.1101/Pdb.Prot4750  0.37
2007 Sive HL, Grainger RM, Harland RM. Xenopus laevis Keller Explants. Csh Protocols. 2007: pdb.prot4749. PMID 21357097 DOI: 10.1101/Pdb.Prot4749  0.356
2007 Sive HL, Grainger RM, Harland RM. Xenopus laevis Animal Cap/Dorsal Mesoderm Conjugates. Csh Protocols. 2007: pdb.prot4748. PMID 21357096 DOI: 10.1101/Pdb.Prot4748  0.388
2007 Sive HL, Grainger RM, Harland RM. Xenopus laevis Animal Cap/Vegetal Endoderm Conjugates. Csh Protocols. 2007: pdb.prot4747. PMID 21357095 DOI: 10.1101/Pdb.Prot4747  0.381
2007 Sive HL, Grainger RM, Harland RM. Animal Cap Isolation from Xenopus laevis. Csh Protocols. 2007: pdb.prot4744. PMID 21357092 DOI: 10.1101/Pdb.Prot4744  0.443
2007 Sive HL, Grainger RM, Harland RM. Housing and Feeding of Xenopus laevis. Csh Protocols. 2007: pdb.top8. PMID 21357089 DOI: 10.1101/Pdb.Top8  0.32
2007 Sive HL, Grainger RM, Harland RM. Embryo dissection and micromanipulation tools. Csh Protocols. 2007: pdb.top7. PMID 21357088 DOI: 10.1101/Pdb.Top7  0.317
2007 Sive HL, Grainger RM, Harland RM. Xenopus laevis In Vitro Fertilization and Natural Mating Methods. Csh Protocols. 2007: pdb.prot4737. PMID 21357082 DOI: 10.1101/Pdb.Prot4737  0.306
2007 Sive HL, Grainger RM, Harland RM. Xenopus laevis Egg Collection. Csh Protocols. 2007: pdb.prot4736. PMID 21357081 DOI: 10.1101/Pdb.Prot4736  0.303
2007 Sive HL, Grainger RM, Harland RM. Inducing Ovulation in Xenopus laevis. Csh Protocols. 2007: pdb.prot4734. PMID 21357079 DOI: 10.1101/Pdb.Prot4734  0.307
2007 Sive HL, Grainger RM, Harland RM. Removing the Vitelline Membrane from Xenopus laevis Embryos. Csh Protocols. 2007: pdb.prot4732. PMID 21357077 DOI: 10.1101/Pdb.Prot4732  0.324
2007 Sive HL, Grainger RM, Harland RM. Dejellying Xenopus laevis Embryos. Csh Protocols. 2007: pdb.prot4731. PMID 21357076 DOI: 10.1101/Pdb.Prot4731  0.3
2006 Ogino H, McConnell WB, Grainger RM. High-throughput transgenesis in Xenopus using I-SceI meganuclease. Nature Protocols. 1: 1703-10. PMID 17487153 DOI: 10.1038/Nprot.2006.208  0.411
2006 Ogino H, McConnell WB, Grainger RM. Highly efficient transgenesis in Xenopus tropicalis using I-SceI meganuclease. Mechanisms of Development. 123: 103-13. PMID 16413175 DOI: 10.1016/J.Mod.2005.11.006  0.447
2005 Noramly S, Zimmerman L, Cox A, Aloise R, Fisher M, Grainger RM. A gynogenetic screen to isolate naturally occurring recessive mutations in Xenopus tropicalis. Mechanisms of Development. 122: 273-87. PMID 15763208 DOI: 10.1016/J.Mod.2004.11.001  0.316
2004 Sullivan CH, Braunstein L, Hazard-Leonards RM, Holen AL, Samaha F, Stephens L, Grainger RM. A re-examination of lens induction in chicken embryos: in vitro studies of early tissue interactions. The International Journal of Developmental Biology. 48: 771-82. PMID 15558470 DOI: 10.1387/Ijdb.041894Cs  0.395
2004 Martynova N, Eroshkin F, Ermakova G, Bayramov A, Gray J, Grainger R, Zaraisky A. Patterning the forebrain: FoxA4a/Pintallavis and Xvent2 determine the posterior limit of Xanf1 expression in the neural plate. Development (Cambridge, England). 131: 2329-38. PMID 15128667 DOI: 10.1242/Dev.01133  0.423
2002 Hirsch N, Zimmerman LB, Gray J, Chae J, Curran KL, Fisher M, Ogino H, Grainger RM. Xenopus tropicalis transgenic lines and their use in the study of embryonic induction. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 225: 522-35. PMID 12454928 DOI: 10.1002/Dvdy.10188  0.651
2002 Hirsch N, Zimmerman LB, Grainger RM. Xenopus, the next generation: X. tropicalis genetics and genomics. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 225: 422-33. PMID 12454920 DOI: 10.1002/Dvdy.10178  0.358
2002 Noramly S, Grainger RM. Determination of the embryonic inner ear. Journal of Neurobiology. 53: 100-28. PMID 12382270 DOI: 10.1002/Neu.10131  0.439
2002 Chae J, Zimmerman LB, Grainger RM. Inducible control of tissue-specific transgene expression in Xenopus tropicalis transgenic lines. Mechanisms of Development. 117: 235-41. PMID 12204263 DOI: 10.1016/S0925-4773(02)00219-8  0.748
2000 Curran KL, Grainger RM. Expression of activated MAP kinase in Xenopus laevis embryos: evaluating the roles of FGF and other signaling pathways in early induction and patterning. Developmental Biology. 228: 41-56. PMID 11087625 DOI: 10.1006/Dbio.2000.9917  0.722
2000 Hirsch N, Grainger RM. Induction of the lens Results and Problems in Cell Differentiation. 31: 51-68. PMID 10929401 DOI: 10.1007/978-3-540-46826-4_4  0.363
2000 Enwright JF, Grainger RM. Altered retinoid signaling in the heads of Small eye mouse embryos Developmental Biology. 221: 10-22. PMID 10772788 DOI: 10.1006/Dbio.2000.9652  0.383
2000 Offield MF, Hirsch N, Grainger RM. The development of Xenopus tropicalis transgenic lines and their use in studying lens developmental timing in living embryos Development. 127: 1789-1797. PMID 10751168  0.394
1998 Zygar CA, Cook TL, Grainger RM. Gene activation during early stages of lens induction in Xenopus. Development (Cambridge, England). 125: 3509-19. PMID 9693153  0.359
1998 Amaya E, Offield MF, Grainger RM. Frog genetics: Xenopus tropicalis jumps into the future Trends in Genetics. 14: 253-255. PMID 9676522 DOI: 10.1016/S0168-9525(98)01506-6  0.381
1997 Saha MS, Miles RR, Grainger RM. Dorsal-ventral patterning during neural induction in Xenopus: Assessment of spinal cord regionalization with xHB9, a marker for the motor neuron region Developmental Biology. 187: 209-223. PMID 9242418 DOI: 10.1006/Dbio.1997.8625  0.329
1997 Grainger RM, Mannion JE, Cook TL, Zygar CA. Defining intermediate stages in cell determination: acquisition of a lens-forming bias in head ectoderm during lens determination. Developmental Genetics. 20: 246-57. PMID 9216064 DOI: 10.1002/(Sici)1520-6408(1997)20:3<246::Aid-Dvg7>3.0.Co;2-7  0.401
1996 Servetnick MD, Cook TL, Grainger RM. Lens induction in axolotls: Comparison with inductive signaling mechanisms in Xenopus laevis International Journal of Developmental Biology. 40: 755-761. PMID 8877449 DOI: 10.1387/Ijdb.8877449  0.352
1996 Gallagher BC, Henry JJ, Grainger RM. Inductive processes leading to inner ear formation during Xenopus development Developmental Biology. 175: 95-107. PMID 8608872 DOI: 10.1006/Dbio.1996.0098  0.392
1996 Grainger RM. New perspectives on embryonic lens induction Seminars in Cell and Developmental Biology. 7: 149-155. DOI: 10.1006/Scdb.1996.0021  0.375
1994 Smolich BD, Tarkington SK, Saha MS, Grainger RM. Xenopus γ-crystallin gene expression: Evidence that the γ-crystallin gene family is transcribed in lens and nonlens tissues Molecular and Cellular Biology. 14: 1355-1363. PMID 7507204 DOI: 10.1128/Mcb.14.2.1355  0.414
1993 Henry JJ, Charlebois TS, Grainger RM. Differential expression of type II cytokeratin mRNA defines early developmental boundaries within the ectoderm, mesoderm and endoderm during chick development. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 202: 355-363. PMID 28306048 DOI: 10.1007/BF00188734  0.306
1993 Smolich BD, Tarkington SK, Saha MS, Stathakis DG, Grainger RM. Characterization of Xenopus laevis gamma-crystallin-encoding genes. Gene. 128: 189-95. PMID 8514186 DOI: 10.1016/0378-1119(93)90562-H  0.333
1993 Saha MS, Grainger RM. Early opsin expression in Xenopus embryos precedes photoreceptor differentiation Molecular Brain Research. 17: 307-318. PMID 8510503 DOI: 10.1016/0169-328X(93)90016-I  0.402
1992 Saha MS, Grainger RM. A labile period in the determination of the anterior-posterior axis during early neural development in Xenopus Neuron. 8: 1003-1014. PMID 1610562 DOI: 10.1016/0896-6273(92)90123-U  0.39
1992 Saha MS, Servetnick M, Grainger RM. Vertebrate eye development Current Opinion in Genetics and Development. 2: 582-588. PMID 1525511 DOI: 10.1016/S0959-437X(05)80176-5  0.314
1992 Grainger RM. Embryonic lens induction: shedding light on vertebrate tissue determination Trends in Genetics. 8: 349-355. PMID 1475847 DOI: 10.1016/0168-9525(92)90280-H  0.382
1991 Sullivan CH, O'Farrell S, Grainger RM. Delta-crystallin gene expression and patterns of hypomethylation demonstrate two levels of regulation for the delta-crystallin genes in embryonic chick tissues. Developmental Biology. 145: 40-50. PMID 2019324 DOI: 10.1016/0012-1606(91)90211-K  0.415
1991 Servetnick M, Grainger RM. Homeogenetic neural induction in xenopus Developmental Biology. 147: 73-82. PMID 1879617 DOI: 10.1016/S0012-1606(05)80008-9  0.353
1990 Henry JJ, Grainger RM. Early tissue interactions leading to embryonic lens formation in Xenopus laevis Developmental Biology. 141: 149-163. PMID 2390999 DOI: 10.1016/0012-1606(90)90110-5  0.407
1990 Charlebois TS, Henry JJ, Grainger RM. Differential cytokeratin gene expression reveals early dorsal-ventral regionalization in chick mesoderm Development. 110: 417-425. PMID 1723943  0.315
1990 Charlebois TS, Spencer DH, Tarkington SK, Henry JJ, Grainger RM. Isolation of a chick cytokeratin cDNA clone indicative of regional specialization in early embryonic ectoderm Development. 108: 33-45. PMID 1693557  0.355
1989 Grainger RM, Gurdon JB. Loss of competence in amphibian induction can take place in single nondividing cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 1900-4. PMID 2928312 DOI: 10.1073/Pnas.86.6.1900  0.348
1989 Saha MS, Spann CL, Grainger RM. Embryonic lens induction: more than meets the optic vesicle Cell Differentiation and Development. 28: 153-171. PMID 2695232 DOI: 10.1016/0922-3371(89)90001-4  0.323
1987 Henry JJ, Grainger RM. Inductive interactions in the spatial and temporal restriction of lens-forming potential in embryonic ectoderm of Xenopus laevis Developmental Biology. 124: 200-214. PMID 3666306 DOI: 10.1016/0012-1606(87)90472-6  0.406
1987 Sullivan CH, Grainger RM. Delta-crystallin genes become hypomethylated in postmitotic lens cells during chicken development. Proceedings of the National Academy of Sciences of the United States of America. 84: 329-33. PMID 3025868 DOI: 10.1073/Pnas.84.2.329  0.377
1986 Peterson CA, Grainger RM. Different protein synthetic patterns in scale-forming, feather-forming, and apteric embryonic chick dermis Developmental Biology. 114: 102-108. PMID 3956858 DOI: 10.1016/0012-1606(86)90386-6  0.348
1985 Peterson CA, Grainger RM. Differentiation of embryonic chick feather-forming and scale-forming tissues in transfilter cultures Developmental Biology. 111: 8-25. PMID 2411616 DOI: 10.1016/0012-1606(85)90430-0  0.327
1983 Grainger RM, Hazard-Leonards RM, Samaha F, Hougan LM, Lesk MR, Thomsen GH. Is hypomethylation linked to activation of delta-crystallin genes during lens development? Nature. 306: 88-91. PMID 6633664 DOI: 10.1038/306088A0  0.398
1981 Pruitt SC, Grainger RM. A mosaicism in the higher order structure of Xenopus oocyte nucleolar chromatin prior to and during ribosomal gene transcription Cell. 23: 711-720. PMID 6939485 DOI: 10.1016/0092-8674(81)90434-7  0.344
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