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Michael Demetriou - Publications

Affiliations: 
Worcester Polytechnic Institute, Worcester, MA, United States 
Area:
Fluid and Plasma Physics, Mechanical Engineering
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sy M, Newton BL, Pawling J, Hayama KL, Cordon A, Yu Z, Kuhle J, Dennis JW, Brandt AU, Demetriou M. N-acetylglucosamine inhibits inflammation and neurodegeneration markers in multiple sclerosis: a mechanistic trial. Journal of Neuroinflammation. 20: 209. PMID 37705084 DOI: 10.1186/s12974-023-02893-9  0.344
2022 Mkhikian H, Demetriou M. T cell senescence by N-glycan branching. Aging. 14: 5964-5965. PMID 35963641 DOI: 10.18632/aging.204239  0.37
2021 Brandt AU, Sy M, Bellmann-Strobl J, Newton BL, Pawling J, Zimmermann HG, Yu Z, Chien C, Dörr J, Wuerfel JT, Dennis JW, Paul F, Demetriou M. Association of a Marker of N-Acetylglucosamine With Progressive Multiple Sclerosis and Neurodegeneration. Jama Neurology. PMID 33970182 DOI: 10.1001/jamaneurol.2021.1116  0.34
2020 Bäcker-Koduah P, Infante-Duarte C, Ivaldi F, Uccelli A, Bellmann-Strobl J, Wernecke KD, Sy M, Demetriou M, Dörr J, Paul F, Ulrich Brandt A. Effect of vitamin D supplementation on N-glycan branching and cellular immunophenotypes in MS. Annals of Clinical and Translational Neurology. PMID 32830462 DOI: 10.1002/Acn3.51148  0.348
2020 Mortales CL, Lee SU, Manousadjian A, Hayama KL, Demetriou M. N-Glycan Branching Decouples B Cell Innate and Adaptive Immunity to Control Inflammatory Demyelination. Iscience. 23: 101380. PMID 32745987 DOI: 10.1016/J.Isci.2020.101380  0.468
2020 Mortales CL, Lee SU, Demetriou M. -Glycan Branching Is Required for Development of Mature B Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 32591389 DOI: 10.4049/Jimmunol.2000101  0.37
2019 Lee SU, Li CF, Mortales CL, Pawling J, Dennis JW, Grigorian A, Demetriou M. Increasing cell permeability of N-acetylglucosamine via 6-acetylation enhances capacity to suppress T-helper 1 (TH1)/TH17 responses and autoimmunity. Plos One. 14: e0214253. PMID 30913278 DOI: 10.1371/Journal.Pone.0214253  0.496
2018 Yale AR, Nourse JL, Lee KR, Ahmed SN, Arulmoli J, Jiang AYL, McDonnell LP, Botten GA, Lee AP, Monuki ES, Demetriou M, Flanagan LA. Cell Surface N-Glycans Influence Electrophysiological Properties and Fate Potential of Neural Stem Cells. Stem Cell Reports. PMID 30197120 DOI: 10.1016/J.Stemcr.2018.08.011  0.382
2017 Araujo L, Khim P, Mkhikian H, Mortales CL, Demetriou M. Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation. Elife. 6. PMID 28059703 DOI: 10.7554/Elife.21330  0.454
2016 Mkhikian H, Mortales CL, Zhou R, Khachikyan K, Wu G, Haslam SM, Kavarian P, Dell A, Demetriou M. Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis. Elife. 5. PMID 27269286 DOI: 10.7554/Elife.14814  0.448
2016 Araujo L, Khim P, Mkhikian H, Mortales C, Demetriou M. Author response: Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation Elife. DOI: 10.7554/Elife.21330.016  0.431
2014 Zhou RW, Mkhikian H, Grigorian A, Hong A, Chen D, Arakelyan A, Demetriou M. N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca²⁺ signaling. Nature Immunology. 15: 1038-45. PMID 25263124 DOI: 10.1038/Ni.3007  0.319
2014 Yu Z, Li CF, Mkhikian H, Zhou RW, Newton BL, Demetriou M. Family studies of type 1 diabetes reveal additive and epistatic effects between MGAT1 and three other polymorphisms. Genes and Immunity. 15: 218-23. PMID 24572742 DOI: 10.1038/Gene.2014.7  0.361
2014 Williams R, Ma X, Schott RK, Mohammad N, Ho CY, Li CF, Chang BS, Demetriou M, Dennis JW. Encoding asymmetry of the N-glycosylation motif facilitates glycoprotein evolution. Plos One. 9: e86088. PMID 24475074 DOI: 10.1371/Journal.Pone.0086088  0.352
2013 Li CF, Zhou RW, Mkhikian H, Newton BL, Yu Z, Demetriou M. Hypomorphic MGAT5 polymorphisms promote multiple sclerosis cooperatively with MGAT1 and interleukin-2 and 7 receptor variants. Journal of Neuroimmunology. 256: 71-6. PMID 23351704 DOI: 10.1016/J.Jneuroim.2012.12.008  0.447
2012 Grigorian A, Mkhikian H, Li CF, Newton BL, Zhou RW, Demetriou M. Pathogenesis of multiple sclerosis via environmental and genetic dysregulation of N-glycosylation. Seminars in Immunopathology. 34: 415-24. PMID 22488447 DOI: 10.1007/S00281-012-0307-Y  0.395
2012 Grigorian A, Mkhikian H, Demetriou M. Interleukin-2, Interleukin-7, T cell-mediated autoimmunity, and N-glycosylation. Annals of the New York Academy of Sciences. 1253: 49-57. PMID 22288682 DOI: 10.1111/J.1749-6632.2011.06391.X  0.468
2011 Grigorian A, Demetriou M. Mgat5 deficiency in T cells and experimental autoimmune encephalomyelitis. Isrn Neurology. 2011: 374314. PMID 22389815 DOI: 10.5402/2011/374314  0.468
2011 Grigorian A, Araujo L, Naidu NN, Place DJ, Choudhury B, Demetriou M. N-acetylglucosamine inhibits T-helper 1 (Th1)/T-helper 17 (Th17) cell responses and treats experimental autoimmune encephalomyelitis. The Journal of Biological Chemistry. 286: 40133-41. PMID 21965673 DOI: 10.1074/Jbc.M111.277814  0.45
2011 Bahaie NS, Kang BN, Frenzel EM, Hosseinkhani MR, Ge XN, Greenberg Y, Ha SG, Demetriou M, Rao SP, Sriramarao P. N-Glycans differentially regulate eosinophil and neutrophil recruitment during allergic airway inflammation. The Journal of Biological Chemistry. 286: 38231-41. PMID 21911487 DOI: 10.1074/Jbc.M111.279554  0.333
2011 Mkhikian H, Grigorian A, Li CF, Chen HL, Newton B, Zhou RW, Beeton C, Torossian S, Tatarian GG, Lee SU, Lau K, Walker E, Siminovitch KA, Chandy KG, Yu Z, ... ... Demetriou M, et al. Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis. Nature Communications. 2: 334. PMID 21629267 DOI: 10.1038/Ncomms1333  0.443
2010 Grigorian A, Demetriou M. Manipulating cell surface glycoproteins by targeting N-glycan-galectin interactions. Methods in Enzymology. 480: 245-66. PMID 20816213 DOI: 10.1016/S0076-6879(10)80012-6  0.455
2009 Dennis JW, Nabi IR, Demetriou M. Metabolism, cell surface organization, and disease. Cell. 139: 1229-41. PMID 20064370 DOI: 10.1016/J.Cell.2009.12.008  0.394
2009 Dennis JW, Lau KS, Demetriou M, Nabi IR. Adaptive regulation at the cell surface by N-glycosylation. Traffic (Copenhagen, Denmark). 10: 1569-78. PMID 19761541 DOI: 10.1111/J.1600-0854.2009.00981.X  0.445
2009 Chen HL, Li CF, Grigorian A, Tian W, Demetriou M. T cell receptor signaling co-regulates multiple Golgi genes to enhance N-glycan branching. The Journal of Biological Chemistry. 284: 32454-61. PMID 19706602 DOI: 10.1074/Jbc.M109.023630  0.445
2009 Grigorian A, Torossian S, Demetriou M. T-cell growth, cell surface organization, and the galectin-glycoprotein lattice. Immunological Reviews. 230: 232-46. PMID 19594640 DOI: 10.1111/J.1600-065X.2009.00796.X  0.471
2007 Chen IJ, Chen HL, Demetriou M. Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling. The Journal of Biological Chemistry. 282: 35361-72. PMID 17897956 DOI: 10.1074/Jbc.M706923200  0.375
2007 Lee SU, Grigorian A, Pawling J, Chen IJ, Gao G, Mozaffar T, McKerlie C, Demetriou M. N-glycan processing deficiency promotes spontaneous inflammatory demyelination and neurodegeneration. The Journal of Biological Chemistry. 282: 33725-34. PMID 17855338 DOI: 10.1074/Jbc.M704839200  0.417
2007 Grigorian A, Lee SU, Tian W, Chen IJ, Gao G, Mendelsohn R, Dennis JW, Demetriou M. Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis. The Journal of Biological Chemistry. 282: 20027-35. PMID 17488719 DOI: 10.1074/Jbc.M701890200  0.489
2007 Lau KS, Partridge EA, Grigorian A, Silvescu CI, Reinhold VN, Demetriou M, Dennis JW. Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation. Cell. 129: 123-34. PMID 17418791 DOI: 10.1016/J.Cell.2007.01.049  0.433
2004 Morgan R, Gao G, Pawling J, Dennis JW, Demetriou M, Li B. N-acetylglucosaminyltransferase V (Mgat5)-mediated N-glycosylation negatively regulates Th1 cytokine production by T cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 7200-8. PMID 15585841 DOI: 10.4049/Jimmunol.173.12.7200  0.428
2002 Dennis JW, Pawling J, Cheung P, Partridge E, Demetriou M. UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6 N-acetylglucosaminyltransferase V (Mgat5) deficient mice. Biochimica Et Biophysica Acta. 1573: 414-22. PMID 12417426 DOI: 10.1016/S0304-4165(02)00411-7  0.46
2001 Dennis JW, Warren CE, Granovsky M, Demetriou M. Genetic defects in N-glycosylation and cellular diversity in mammals Current Opinion in Structural Biology. 11: 601-607. PMID 11785762 DOI: 10.1016/S0959-440X(00)00254-2  0.448
2001 Demetriou M, Granovsky M, Quaggin S, Dennis JW. Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation. Nature. 409: 733-9. PMID 11217864 DOI: 10.1038/35055582  0.491
1995 Demetriou M, Nabi IR, Coppolino M, Dedhar S, Dennis JW. Reduced contact-inhibition and substratum adhesion in epithelial cells expressing GlcNAc-transferase V. The Journal of Cell Biology. 130: 383-92. PMID 7615638 DOI: 10.1083/Jcb.130.2.383  0.363
1993 Simon HU, Higgins EA, Demetriou M, Datti A, Siminovitch KA, Dennis JW. Defective expression of CD23 and autocrine growth-stimulation in Epstein-Barr virus (EBV)-transformed B cells from patients with Wiskott-Aldrich syndrome (WAS). Clinical and Experimental Immunology. 91: 43-9. PMID 8380367 DOI: 10.1111/J.1365-2249.1993.Tb03351.X  0.317
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