Chi Van Dang, M.D., Ph.D. - Publications

Abramson Cancer Center University of Pennsylvania, Philadelphia, PA, United States 
Cancer metabolism

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Year Citation  Score
2021 Harrington CT, Sotillo E, Dang CV, Thomas-Tikhonenko A. Tilting MYC toward cancer cell death. Trends in Cancer. PMID 34481764 DOI: 10.1016/j.trecan.2021.08.002  1
2021 Tang HY, Goldman AR, Zhang X, Speicher DW, Dang CV. Measuring MYC-Mediated Metabolism in Tumorigenesis. Methods in Molecular Biology (Clifton, N.J.). 2318: 231-239. PMID 34019293 DOI: 10.1007/978-1-0716-1476-1_11  1
2021 Wolpaw AJ, Bayliss R, Büchel G, Dang CV, Eilers M, Gustafson WC, Hansen GM, Jura N, Knapp S, Lemmon MA, Levens D, Maris JM, Marmorstein R, Metallo SJ, Park JR, et al. Drugging the 'undruggable' MYCN oncogenic transcription factor: Overcoming previous obstacles to impact childhood cancers. Cancer Research. PMID 33509943 DOI: 10.1158/0008-5472.CAN-20-3108  0.04
2020 Rai G, Urban DJ, Mott BT, Hu X, Yang SM, Benavides GA, Johnson MS, Squadrito GL, Brimacombe KR, Lee TD, Cheff DM, Zhu H, Henderson MJ, Pohida K, Sulikowski GA, ... ... Dang CV, et al. Pyrazole-Based Lactate Dehydrogenase (LDH) Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. Journal of Medicinal Chemistry. PMID 32902275 DOI: 10.1021/Acs.Jmedchem.0C00916  1
2020 Oshima N, Ishida R, Kishimoto S, Beebe K, Brender JR, Yamamoto K, Urban D, Rai G, Johnson MS, Benavides G, Squadrito GL, Crooks D, Jackson J, Joshi A, Mott BT, ... ... Dang CV, et al. Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy. Cell Reports. 30: 1798-1810.e4. PMID 32049011 DOI: 10.1016/J.Celrep.2020.01.039  1
2019 Dang CV. Essentiality of non-essential amino acids for tumour cells and tumorigenesis. Nature Metabolism. 1: 847-848. PMID 32694747 DOI: 10.1038/s42255-019-0113-0  0.01
2019 Stine ZE, Dang CV. Glutamine Skipping the Q into Mitochondria. Trends in Molecular Medicine. PMID 31866300 DOI: 10.1016/j.molmed.2019.11.004  1
2019 Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein PS, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A. Correction: Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma. Leukemia. PMID 31758088 DOI: 10.1038/S41375-019-0650-2  1
2019 Hsieh AL, Zheng X, Yue Z, Stine ZE, Mancuso A, Rhoades SD, Brooks R, Weljie AM, Eisenman RN, Sehgal A, Dang CV. Misregulation of Drosophila Myc Disrupts Circadian Behavior and Metabolism. Cell Reports. 29: 1778-1788.e4. PMID 31722196 DOI: 10.1016/J.Celrep.2019.10.022  1
2019 Gouw AM, Margulis K, Liu NS, Raman SJ, Mancuso A, Toal GG, Tong L, Mosley A, Hsieh AL, Sullivan DK, Stine ZE, Altman BJ, Schulze A, Dang CV, Zare RN, et al. The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth. Cell Metabolism. PMID 31447321 DOI: 10.1016/J.Cmet.2019.07.012  1
2019 Fan TWM, Bruntz RC, Yang Y, Song H, Chernyavskaya Y, Deng P, Zhang Y, Shah PP, Beverly LJ, Qi Z, Mahan AL, Higashi RM, Dang CV, Lane AN. De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues. The Journal of Biological Chemistry. PMID 31337706 DOI: 10.1074/jbc.RA119.008743  1
2019 Walton ZE, Brooks RC, Dang CV. mTOR Senses Intracellular pH through Lysosome Dispersion from RHEB. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e1800265. PMID 31157925 DOI: 10.1002/bies.201800265  1
2019 Brooks RC, Dang CV. Autophagy: clocking in for the night shift. The Embo Journal. PMID 31133555 DOI: 10.15252/Embj.2019102434  1
2019 Agarwal E, Altman BJ, Seo JH, Ghosh JC, Kossenkov AV, Tang HY, Krishn SR, Languino LR, Gabrilovich DI, Speicher DW, Dang CV, Altieri DC. Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth. The Journal of Biological Chemistry. PMID 31097545 DOI: 10.1074/Jbc.Ac119.008656  1
2019 Agarwal E, Altman BJ, Seo JH, Bertolini I, Ghosh JC, Kaur A, Kossenkov AV, Languino LR, Gabrilovich DI, Speicher DW, Dang CV, Altieri DC. MYC REGULATION OF A MITOCHONDRIAL TRAFFICKING NETWORK MEDIATES TUMOR CELL INVASION AND METASTASIS. Molecular and Cellular Biology. PMID 31061095 DOI: 10.1128/Mcb.00109-19  1
2019 Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein P, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A. Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma. Leukemia. PMID 30914792 DOI: 10.1038/s41375-019-0454-4  1
2018 Dang CV. Cancer Metabolism: the Known, Unknowns. Biochimica Et Biophysica Acta. Reviews On Cancer. 1870: 1. PMID 30336841 DOI: 10.1016/j.bbcan.2018.07.006  0.01
2018 Yuan J, Hu Z, Mahal BA, Zhao SD, Kensler KH, Pi J, Hu X, Zhang Y, Wang Y, Jiang J, Li C, Zhong X, Montone KT, Guan G, Tanyi JL, ... ... Dang CV, et al. Integrated Analysis of Genetic Ancestry and Genomic Alterations across Cancers. Cancer Cell. 34: 549-560.e9. PMID 30300578 DOI: 10.1016/J.Ccell.2018.08.019  1
2018 Zhang L, Peng D, Sood AK, Dang CV, Zhong X. Shedding Light on the Dark Cancer Genomes: Long Noncoding RNAs as Novel Biomarkers and Potential Therapeutic Targets for Cancer. Molecular Cancer Therapeutics. 17: 1816-1823. PMID 30181330 DOI: 10.1158/1535-7163.Mct-18-0124  1
2018 Dang CV. The Half-Lives of Facts, Paradigm Shifts, and Reproducibility in Cancer Research. Cancer Research. 78: 4105-4106. PMID 30068666 DOI: 10.1158/0008-5472.CAN-18-1751  0.01
2018 Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, ... ... Dang CV, et al. Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR. Cell. PMID 29861175 DOI: 10.1016/J.Cell.2018.05.009  1
2018 Wolpaw AJ, Dang CV. MYC-induced metabolic stress and tumorigenesis. Biochimica Et Biophysica Acta. PMID 29791870 DOI: 10.1016/J.Bbcan.2018.05.003  0.01
2018 Dang CV. Convergence to Cure Cancer through Research: A Message from the New Editor-in-Chief. Cancer Research. 78: 3-4. PMID 29298804 DOI: 10.1158/0008-5472.CAN-17-3771  0.01
2017 Bu Y, Yoshida A, Chitnis N, Altman BJ, Tameire F, Oran A, Gennaro V, Armeson KE, McMahon SB, Wertheim GB, Dang CV, Ruggero D, Koumenis C, Fuchs SY, Diehl JA. A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival. Nature Cell Biology. PMID 29230015 DOI: 10.1038/S41556-017-0006-Y  1
2017 Wolpaw AJ, Dang CV. Exploiting Metabolic Vulnerabilities of Cancer with Precision and Accuracy. Trends in Cell Biology. PMID 29229182 DOI: 10.1016/J.Tcb.2017.11.006  0.01
2017 Jaffee EM, Dang CV, Agus DB, Alexander BM, Anderson KC, Ashworth A, Barker AD, Bastani R, Bhatia S, Bluestone JA, Brawley O, Butte AJ, Coit DG, Davidson NE, Davis M, et al. Future cancer research priorities in the USA: a Lancet Oncology Commission. The Lancet. Oncology. 18: e653-e706. PMID 29208398 DOI: 10.1016/S1470-2045(17)30698-8  0.12
2017 Lu Y, Hu Z, Mangala LS, Stine ZE, Hu X, Jiang D, Xiang Y, Zhang Y, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Demarzo A, Sood AK, Zhang L, Dang CV. MYC targeted long non-coding RNA DANCR promotes cancer in part by reducing p21 levels. Cancer Research. PMID 29180471 DOI: 10.1158/0008-5472.Can-17-0815  1
2017 Zhang Y, Dang CV, Zhang L. BETting on combination to overcome PARPi resistance. Oncotarget. 8: 84630-84631. PMID 29156666 DOI: 10.18632/Oncotarget.21446  1
2017 Dang CV. Feeding frenzy for cancer cells. Science (New York, N.Y.). 358: 862-863. PMID 29146793 DOI: 10.1126/science.aaq1070  0.01
2017 Rai G, Brimacombe KR, Mott BT, Urban DJ, Hu X, Yang SM, Lee TD, Cheff DM, Kouznetsova J, Benavides GA, Pohida K, Kuenstner EJ, Luci DK, Lukacs CM, Davies DR, ... ... Dang CV, et al. Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). Journal of Medicinal Chemistry. PMID 29120638 DOI: 10.1021/Acs.Jmedchem.7B00941  1
2017 Hu X, Sood AK, Dang CV, Zhang L. The role of long noncoding RNAs in cancer: the dark matter matters. Current Opinion in Genetics & Development. 48: 8-15. PMID 29054012 DOI: 10.1016/J.Gde.2017.10.004  1
2017 Yang L, Zhang Y, Shan W, Hu Z, Yuan J, Pi J, Wang Y, Fan L, Tang Z, Li C, Hu X, Tanyi JL, Fan Y, Huang Q, Montone K, ... Dang CV, et al. Repression of BET activity sensitizes homologous recombination-proficient cancers to PARP inhibition. Science Translational Medicine. 9. PMID 28747513 DOI: 10.1126/Scitranslmed.Aal1645  1
2017 Dang CV. MUC-king with HIF May Rewire Pyrimidine Biosynthesis and Curb Gemcitabine Resistance in Pancreatic Cancer. Cancer Cell. 32: 3-5. PMID 28697341 DOI: 10.1016/j.ccell.2017.06.006  0.01
2017 Dang CV, Reddy EP, Shokat KM, Soucek L. Drugging the 'undruggable' cancer targets. Nature Reviews. Cancer. PMID 28643779 DOI: 10.1038/Nrc.2017.36  0.04
2017 Rajeshkumar NV, Yabuuchi S, Pai S, De Oliveira E, Kamphorst JJ, Rabinowitz JD, Tejero H, Al-Shahrour F, Hidalgo M, Maitra A, Dang CV. Treatment of pancreatic cancer patient-derived xenograft panel with metabolic inhibitors reveals efficacy of phenformin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28611197 DOI: 10.1158/1078-0432.Ccr-17-1115  1
2017 Dang CV. c-MYC mRNA tail tale about glutamine control of transcription. The Embo Journal. PMID 28507224 DOI: 10.15252/Embj.201796999  0.01
2017 Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, ... ... Dang CV, et al. Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism. Cell Metabolism. 25: 1206. PMID 28467936 DOI: 10.1016/J.Cmet.2017.04.023  1
2017 Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, ... ... Dang CV, et al. Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism. Cell Metabolism. 25: 961-974.e4. PMID 28380384 DOI: 10.1016/J.Cmet.2017.03.019  1
2017 Borazanci E, Dang CV, Robey RW, Bates SE, Chabot JA, Von Hoff DD. Pancreatic Cancer: "A Riddle Wrapped in a Mystery inside an Enigma". Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: 1629-1637. PMID 28373361 DOI: 10.1158/1078-0432.Ccr-16-2070  0.01
2017 Altman BJ, Hsieh AL, Gouw AM, Dang CV. Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα. Nature Communications. 8: 14862. PMID 28332504 DOI: 10.1038/Ncomms14862  1
2017 Dang CV. A Time for MYC: Metabolism and Therapy. Cold Spring Harbor Symposia On Quantitative Biology. PMID 28174256 DOI: 10.1101/Sqb.2016.81.031153  0.01
2017 Dang CV. Mixed outcomes for computational predictions. Elife. 6. PMID 28100399 DOI: 10.7554/eLife.22661  0.01
2016 Altman BJ, Stine ZE, Dang CV. From Krebs to clinic: glutamine metabolism to cancer therapy. Nature Reviews. Cancer. 16: 749. PMID 28704361 DOI: 10.1038/nrc.2016.114  1
2016 Altman BJ, Stine ZE, Dang CV. From Krebs to clinic: glutamine metabolism to cancer therapy. Nature Reviews. Cancer. 16: 773. PMID 28704359 DOI: 10.1038/Nrc.2016.131  1
2016 Xu Q, Zhang Q, Ishida Y, Hajjar S, Tang X, Shi H, Dang CV, Le AD. EGF induces epithelial-mesenchymal transition and cancer stem-like cell properties in human oral cancer cells via promoting Warburg effect. Oncotarget. PMID 27926487 DOI: 10.18632/Oncotarget.13771  0.28
2016 Huang, Li T, Wang L, Zhang L, Yan R, Li K, Xing S, Wu G, Hu L, Jia W, Lin SC, Dang CV, Song L, Gao P, Zhang H. Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress. Cell Research. PMID 27644987 DOI: 10.1038/Cr.2016.109  1
2016 Hsieh AL, Dang CV. MYC, Metabolic Synthetic Lethality, and Cancer. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 207: 73-91. PMID 27557535 DOI: 10.1007/978-3-319-42118-6_4  1
2016 Altman BJ, Stine ZE, Dang CV. From Krebs to clinic: glutamine metabolism to cancer therapy. Nature Reviews. Cancer. PMID 27492215 DOI: 10.1038/Nrc.2016.71  1
2016 Zhang Y, He Q, Hu Z, Feng Y, Fan L, Tang Z, Yuan J, Shan W, Li C, Hu X, Tanyi JL, Fan Y, Huang Q, Montone K, Dang CV, et al. Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer. Nature Structural & Molecular Biology. PMID 27111890 DOI: 10.1038/Nsmb.3211  1
2016 Dang CV. Abstract SY12-03: MYC-mediated metabolic vulnerabilities and the circadian clock Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Sy12-03  0.01
2016 Stine Z, Walton ZE, Zhang L, Fan TM, Lane AN, Dang CV. Abstract 2669: Glutaminase alternative splicing controls tumor growth and metabolism Cancer Research. 76: 2669-2669. DOI: 10.1158/1538-7445.Am2016-2669  1
2015 Stine ZE, Dang CV. Q-ing tumor glutaminase for therapy. Oncotarget. PMID 26564960 DOI: 10.18632/Oncotarget.6301  1
2015 Yan X, Hu Z, Feng Y, Hu X, Yuan J, Zhao SD, Zhang Y, Yang L, Shan W, He Q, Fan L, Kandalaft LE, Tanyi JL, Li C, Yuan CX, ... ... Dang CV, et al. Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers. Cancer Cell. 28: 529-40. PMID 26461095 DOI: 10.1016/J.Ccell.2015.09.006  1
2015 Matkar S, Sharma P, Gao S, Gurung B, Katona BW, Liao J, Muhammad AB, Kong XC, Wang L, Jin G, Dang CV, Hua X. An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis. Cancer Cell. 28: 472-85. PMID 26461093 DOI: 10.1016/J.Ccell.2015.09.005  1
2015 Stine ZE, Dang CV. Splicing and Dicing MYC-Mediated Synthetic Lethality. Cancer Cell. 28: 405-6. PMID 26461086 DOI: 10.1016/J.Ccell.2015.09.016  1
2015 Altman BJ, Hsieh AL, Sengupta A, Krishnanaiah SY, Stine ZE, Walton ZE, Gouw AM, Venkataraman A, Li B, Goraksha-Hicks P, Diskin SJ, Bellovin DI, Simon MC, Rathmell JC, Lazar MA, ... ... Dang CV, et al. MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells. Cell Metabolism. 22: 1009-19. PMID 26387865 DOI: 10.1016/J.Cmet.2015.09.003  1
2015 Stine ZE, Walton ZE, Altman BJ, Hsieh AL, Dang CV. MYC, Metabolism, and Cancer. Cancer Discovery. 5: 1024-39. PMID 26382145 DOI: 10.1158/2159-8290.Cd-15-0507  1
2015 Ji Z, Vokes SA, Dang CV, Ji H. Turning publicly available gene expression data into discoveries using gene set context analysis. Nucleic Acids Research. PMID 26350211 DOI: 10.1093/Nar/Gkv873  1
2015 Hsieh AL, Walton ZE, Altman BJ, Stine ZE, Dang CV. MYC and metabolism on the path to cancer. Seminars in Cell & Developmental Biology. PMID 26277543 DOI: 10.1016/J.Semcdb.2015.08.003  1
2015 Dang MT, Wehrli S, Dang CV, Curran T. The Ketogenic Diet Does Not Affect Growth of Hedgehog Pathway Medulloblastoma in Mice. Plos One. 10: e0133633. PMID 26192445 DOI: 10.1371/Journal.Pone.0133633  1
2015 Rajeshkumar NV, Dutta P, Yabuuchi S, de Wilde RF, Matrinez GV, Le A, Kamphorst JJ, Rabinowitz JD, Jain SK, Hidalgo M, Dang CV, Gillies RJ, Maitra A. Therapeutic targeting of the Warburg effect in pancreatic cancer relies on an absence of p53 function. Cancer Research. PMID 26113084 DOI: 10.1158/0008-5472.Can-15-0108  1
2015 Dang CV. A metabolic perspective of Peto's paradox and cancer. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26056367 DOI: 10.1098/rstb.2014.0223  0.01
2015 Shroff EH, Eberlin LS, Dang VM, Gouw AM, Gabay M, Adam SJ, Bellovin DI, Tran PT, Philbrick WM, Garcia-Ocana A, Casey SC, Li Y, Dang CV, Zare RN, Felsher DW. MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism. Proceedings of the National Academy of Sciences of the United States of America. 112: 6539-44. PMID 25964345 DOI: 10.1073/Pnas.1507228112  1
2015 Xiang Y, Stine ZE, Xia J, Lu Y, O'Connor RS, Altman BJ, Hsieh AL, Gouw AM, Thomas AG, Gao P, Sun L, Song L, Yan B, Slusher BS, Zhuo J, ... ... Dang CV, et al. Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. The Journal of Clinical Investigation. 125: 2293-306. PMID 25915584 DOI: 10.1172/Jci75836  1
2015 Korangath P, Teo WW, Sadik H, Han L, Mori N, Huijts CM, Wildes F, Bharti S, Zhang Z, Santa-Maria CA, Tsai H, Dang CV, Stearns V, Bhujwalla ZM, Sukumar S. Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 3263-73. PMID 25813021 DOI: 10.1158/1078-0432.Ccr-14-1200  1
2015 Dang CV. Web of the Extended Myc Network Captures Metabolism for Tumorigenesis Cancer Cell. 27: 160-162. PMID 25670077 DOI: 10.1016/J.Ccell.2015.01.004  1
2015 Stine ZE, Walton ZE, Altman BJ, Hsieh AL, Dang CV. MYC, metabolism, and cancer Cancer Discovery. 5: 1024-1039. DOI: 10.1158/2159-8290.CD-15-0507  1
2015 Altman BJ, Stine ZE, Hsieh AL, Deberardinis RJ, Dang CV. Abstract 4708: Mammalian glutamine metabolism controls circadian rhythm through regulation of reactive oxygen species Cancer Research. 75: 4708-4708. DOI: 10.1158/1538-7445.Am2015-4708  1
2015 Dang CV. A metabolic perspective of peto’s paradox and cancer Philosophical Transactions of the Royal Society B: Biological Sciences. 370. DOI: 10.1098/rstb.2014.0223  1
2015 Gouw AM, Hsieh AL, Stine ZE, Dang CV. MYC regulation of metabolism and cancer Tumor Cell Metabolism: Pathways, Regulation and Biology. 101-122. DOI: 10.1007/978-3-7091-1824-5_5  1
2014 Le A, Stine ZE, Nguyen C, Afzal J, Sun P, Hamaker M, Siegel NM, Gouw AM, Kang BH, Yu SH, Cochran RL, Sailor KA, Song H, Dang CV. Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia-cell cycle dual reporter. Proceedings of the National Academy of Sciences of the United States of America. 111: 12486-91. PMID 25114222 DOI: 10.1073/Pnas.1402012111  1
2014 Dang CV. Gene regulation: Fine-tuned amplification in cells Nature. 511: 417-418. PMID 25043013 DOI: 10.1038/Nature13518  1
2014 Emadi A, Jun SA, Tsukamoto T, Fathi AT, Minden MD, Dang CV. Inhibition of glutaminase selectively suppresses the growth of primary acute myeloid leukemia cells with IDH mutations. Experimental Hematology. 42: 247-51. PMID 24333121 DOI: 10.1016/J.Exphem.2013.12.001  1
2014 Doherty JR, Yang C, Scott KE, Cameron MD, Fallahi M, Li W, Hall MA, Amelio AL, Mishra JK, Li F, Tortosa M, Genau HM, Rounbehler RJ, Lu Y, Dang CV, et al. Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis. Cancer Research. 74: 908-20. PMID 24285728 DOI: 10.1158/0008-5472.Can-13-2034  1
2014 Stine Z, Xiang Y, Xia J, Gao P, Dinavahi R, Dang CV. Abstract 2957: Inhibition of glutaminase induces slows tumor growth cell autonomously and promotes survival in a MYC driven hepatocellular carcinoma mouse model Cancer Research. 74: 2957-2957. DOI: 10.1158/1538-7445.Am2014-2957  1
2014 Altman BJ, Hsieh A, Gouw AM, Stine ZE, Venkataraman A, Bellovin DI, Diskin SJ, Lu W, Zhang S, Felsher DW, Maris JM, Lazar MA, Rabinowitz JD, Hogenesch JB, Dang CV. Abstract 2953: Rev-erbα modulates Myc-driven cancer cell growth and altered metabolism Cancer Research. 74: 2953-2953. DOI: 10.1158/1538-7445.Am2014-2953  1
2014 Hsieh AL, Altman BJ, Venkataraman A, Bellovin DI, Felsher DW, Hogenesch JB, Dang CV. Abstract 1419: Oncogenic Myc disrupts NAMPT circadian oscillation in mouse hepatocellular carcinoma cell line Cancer Research. 74: 1419-1419. DOI: 10.1158/1538-7445.Am2014-1419  1
2014 Stine ZE, Dang CV. Overview Metabolism of Human Diseases: Organ Physiology and Pathophysiology. 393-399. DOI: 10.1007/978-3-7091-0715-7_57  1
2013 Ngo AD, Ha TH, Rule J, Dang CV. Peer-based education and the integration of HIV and Sexual and Reproductive Health services for young people in Vietnam: evidence from a project evaluation. Plos One. 8: e80951. PMID 24312253 DOI: 10.1371/journal.pone.0080951  1
2013 Stine ZE, Dang CV. Stress eating and tuning out: Cancer cells re-wire metabolism to counter stress Critical Reviews in Biochemistry and Molecular Biology. 48: 609-619. PMID 24099138 DOI: 10.3109/10409238.2013.844093  1
2013 Le A, Dang CV. Studying Myc's role in metabolism regulation. Methods in Molecular Biology (Clifton, N.J.). 1012: 213-9. PMID 24006067 DOI: 10.1007/978-1-62703-429-6_14  1
2013 Dang CV. MYC, metabolism, cell growth, and tumorigenesis. Cold Spring Harbor Perspectives in Medicine. 3. PMID 23906881 DOI: 10.1101/Cshperspect.A014217  0.01
2013 Dutta P, Le A, Vander Jagt DL, Tsukamoto T, Martinez GV, Dang CV, Gillies RJ. Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors. Cancer Research. 73: 4190-5. PMID 23722553 DOI: 10.1158/0008-5472.Can-13-0465  1
2013 Wu G, Yustein JT, McCall MN, Zilliox M, Irizarry RA, Zeller K, Dang CV, Ji H. ChIP-PED enhances the analysis of ChIP-seq and ChIP-chip data. Bioinformatics (Oxford, England). 29: 1182-1189. PMID 23457041 DOI: 10.1093/Bioinformatics/Btt108  1
2013 Hubbi ME, Kshitiz, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL. A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication Science Signaling. 6. PMID 23405012 DOI: 10.1126/Scisignal.2003417  1
2013 Dang CV. Role of aerobic glycolysis in genetically engineered mouse models of cancer Bmc Biology. 11. PMID 23342984 DOI: 10.1186/1741-7007-11-3  1
2013 Eisenman RN, Dang CV. Unlocking the mysterious mechanisms of myc Nature Medicine. 19: 26-27. PMID 23296005 DOI: 10.1038/Nm.3060  0.04
2013 Zhan H, Cardozo C, Yu W, Wang A, Moliterno AR, Dang CV, Spivak JL. MicroRNA deregulation in polycythemia vera and essential thrombocythemia patients Blood Cells, Molecules, and Diseases. 50: 190-195. PMID 23265742 DOI: 10.1016/J.Bcmd.2012.11.009  1
2013 Murphy TA, Dang CV, Young JD. Isotopically nonstationary 13C flux analysis of Myc-induced metabolic reprogramming in B-cells Metabolic Engineering. 15: 206-217. PMID 22898717 DOI: 10.1016/J.Ymben.2012.07.008  1
2013 Poore B, Park JK, Afif I, Shingleton L, Dang CV, Le A. Abstract 852: Novel role and mechanism of the LDHA protein as a survival factor for cancer cells. Cancer Research. 73: 852-852. DOI: 10.1158/1538-7445.Am2013-852  1
2013 Rajeshkumar NV, Yabuuchi S, Patel C, Pai SG, Le DT, Hoff DDV, Dang CV, Maitra A, Powell J. Abstract 5396: Targeting multiple components of the mammalian target of rapamycin (mTOR) signaling: A novel combination therapy to improve pancreatic cancer treatment. Cancer Research. 73: 5396-5396. DOI: 10.1158/1538-7445.Am2013-5396  1
2013 Altman BJ, Hsieh A, Gouw A, Venkataraman A, Li B, Bellovin D, Simon MC, Felsher D, Hogenesch J, Dang CV. Abstract 4616: Oncogenic c- and N-Myc disrupt circadian rhythm. Cancer Research. 73: 4616-4616. DOI: 10.1158/1538-7445.Am2013-4616  1
2013 Gouw AM, Mancuso A, Hsieh AL, Altman B, Wolfgang M, Dang CV. Abstract 1879: Myc induces lipogenesis and suppresses fatty acid oxidation in human P493-6 B-lymphoma cells. Cancer Research. 73: 1879-1879. DOI: 10.1158/1538-7445.Am2013-1879  1
2013 Dang CV. MYC, metabolism, cell growth, and tumorigenesis Cold Spring Harbor Perspectives in Biology. 5. DOI: 10.1101/cshperspect.a014217  1
2012 Shukla K, Ferraris DV, Thomas AG, Stathis M, Duvall B, Delahanty G, Alt J, Rais R, Rojas C, Gao P, Xiang Y, Dang CV, Slusher BS, Tsukamoto T. Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors. Journal of Medicinal Chemistry. 55: 10551-63. PMID 23151085 DOI: 10.1021/Jm301191P  1
2012 Le A, Rajeshkumar NV, Maitra A, Dang CV. Conceptual framework for cutting the pancreatic cancer fuel supply. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4285-90. PMID 22896695 DOI: 10.1158/1078-0432.Ccr-12-0041  1
2012 Altman BJ, Dang CV. Normal and cancer cell metabolism: Lymphocytes and lymphoma Febs Journal. 279: 2598-2609. PMID 22672505 DOI: 10.1111/J.1742-4658.2012.08651.X  1
2012 Liu W, Le A, Hancock C, Lane AN, Dang CV, Fan TW, Phang JM. Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC. Proceedings of the National Academy of Sciences of the United States of America. 109: 8983-8. PMID 22615405 DOI: 10.1073/Pnas.1203244109  1
2012 Dang CV. Cancer cell metabolism: There is no ROS for the weary Cancer Discovery. 2: 304-307. PMID 22576206 DOI: 10.1158/2159-8290.Cd-12-0069  1
2012 Dang CV. Links between metabolism and cancer Genes and Development. 26: 877-890. PMID 22549953 DOI: 10.1101/Gad.189365.112  1
2012 Dang CV. MYC on the path to cancer Cell. 149: 22-35. PMID 22464321 DOI: 10.1016/J.Cell.2012.03.003  1
2012 Dang CV. Old and fat, oncogenes make you Cell Cycle. 11: 1271-1272. PMID 22426417 DOI: 10.4161/Cc.19905  1
2012 Le A, Lane AN, Hamaker M, Bose S, Gouw A, Barbi J, Tsukamoto T, Rojas CJ, Slusher BS, Zhang H, Zimmerman LJ, Liebler DC, Slebos RJ, Lorkiewicz PK, Higashi RM, ... ... Dang CV, et al. Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. Cell Metabolism. 15: 110-21. PMID 22225880 DOI: 10.1016/J.Cmet.2011.12.009  1
2012 Fan J, Chen YC, Watkins T, Dang CV, Gorospe M, Cheadle C. Array-based nuclear run-on analysis Methods in Molecular Biology. 809: 505-517. PMID 22113297 DOI: 10.1007/978-1-61779-376-9_33  1
2012 Rajeshkumar NV, Dutta P, Kamphorst J, Le A, Yabuuchi S, Wilde RFd, Campbell NR, Oliveira ED, Jesus-Acosta AD, Rabinowitz J, Laheru D, Jain SK, Hidalgo M, Thompson CB, Hoff DDV, ... ... Dang CV, et al. Abstract LB-61: Targeting cancer cell metabolism in pancreatic cancer: p53, a key regulator of glycolysis and a major factor deciding the outcome of targeting the Warburg effect Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-61  1
2012 Gouw AM, Hsieh AL, Le A, Maitra A, Dang CV. Abstract 5242: Pancreatic cancer cell type specific oxygen dependent growth and drug sensitivity Cancer Research. 72: 5242-5242. DOI: 10.1158/1538-7445.Am2012-5242  1
2011 Ji H, Wu G, Zhan X, Nolan A, Koh C, de Marzo A, Doan HM, Fan J, Cheadle C, Fallahi M, Cleveland JL, Dang CV, Zeller KI. Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation Plos One. 6. PMID 22039435 DOI: 10.1371/Journal.Pone.0026057  1
2011 Emadi A, Le A, Harwood CJ, Stagliano KW, Kamangar F, Ross AE, Cooper CR, Dang CV, Karp JE, Vuica-Ross M. Metabolic and electrochemical mechanisms of dimeric naphthoquinones cytotoxicity in breast cancer cells. Bioorganic & Medicinal Chemistry. 19: 7057-62. PMID 22036210 DOI: 10.1016/J.Bmc.2011.10.005  1
2011 Dang CV. Therapeutic targeting of Myc-reprogrammed cancer cell metabolism Cold Spring Harbor Symposia On Quantitative Biology. 76: 369-374. PMID 21960526 DOI: 10.1101/Sqb.2011.76.011296  1
2011 Dang EV, Barbi J, Yang HY, Jinasena D, Yu H, Zheng Y, Bordman Z, Fu J, Kim Y, Yen HR, Luo W, Zeller K, Shimoda L, Topalian SL, Semenza GL, ... Dang CV, et al. Control of TH17/Treg balance by hypoxia-inducible factor 1 Cell. 146: 772-784. PMID 21871655 DOI: 10.1016/J.Cell.2011.07.033  1
2011 Koppenol WH, Bounds PL, Dang CV. Otto Warburg's contributions to current concepts of cancer metabolism Nature Reviews Cancer. 11: 325-337. PMID 21508971 DOI: 10.1038/Nrc3038  1
2011 Koh CM, Gurel B, Sutcliffe S, Aryee MJ, Schultz D, Iwata T, Uemura M, Zeller KI, Anele U, Zheng Q, Hicks JL, Nelson WG, Dang CV, Yegnasubramanian S, De Marzo AM. Alterations in nucleolar structure and gene expression programs in prostatic neoplasia are driven by the MYC oncogene. The American Journal of Pathology. 178: 1824-34. PMID 21435462 DOI: 10.1016/J.Ajpath.2010.12.040  1
2011 Dang CV, Hamaker M, Sun P, Le A, Gao P. Therapeutic targeting of cancer cell metabolism. Journal of Molecular Medicine (Berlin, Germany). 89: 205-12. PMID 21301795 DOI: 10.1007/S00109-011-0730-X  1
2011 Ji H, Wu G, Zhan X, Nolan A, Koh C, Marzo AD, Fan J, Cheadle C, Fallahi M, Cleveland J, Dang CV, Zeller K. Abstract 928: Species and cell type independent core MYC target genes in cancer and stem cells Cancer Research. 71: 928-928. DOI: 10.1158/1538-7445.Am2011-928  1
2011 Le A, Hamaker M, Zhang H, Zimmerman LJ, Dinavahi R, Gao P, Liebler DC, Slebos RJC, Moseley H, Higashi RM, Lane A, Fan TWM, Dang CV. Abstract 2799: Unexpected sustained hypoxic glutamine metabolism and therapeutic opportunities Cancer Research. 71: 2799-2799. DOI: 10.1158/1538-7445.Am2011-2799  1
2011 Koppenol WH, Bounds PL, Dang CV. Erratum: Otto Warburg's contributions to current concepts of cancer metabolism Nature Reviews Cancer. 11: 618-618. DOI: 10.1038/Nrc3108  1
2010 Koh CM, Bieberich CJ, Dang CV, Nelson WG, Yegnasubramanian S, De Marzo AM. MYC and Prostate Cancer. Genes & Cancer. 1: 617-28. PMID 21779461 DOI: 10.1177/1947601910379132  1
2010 Dang CV. Enigmatic MYC Conducts an Unfolding Systems Biology Symphony. Genes & Cancer. 1: 526-531. PMID 21218193 DOI: 10.1177/1947601910378742  0.01
2010 Seltzer MJ, Bennett BD, Joshi AD, Gao P, Thomas AG, Ferraris DV, Tsukamoto T, Rojas CJ, Slusher BS, Rabinowitz JD, Dang CV, Riggins GJ. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Research. 70: 8981-7. PMID 21045145 DOI: 10.1158/0008-5472.Can-10-1666  1
2010 Dang CV. Glutaminolysis: Supplying carbon or nitrogen or both for cancer cells? Cell Cycle. 9: 3884-3886. PMID 20948290 DOI: 10.4161/Cc.9.19.13302  1
2010 Otto EA, Hurd TW, Airik R, Chaki M, Zhou W, Stoetzel C, Patil SB, Levy S, Ghosh AK, Murga-Zamalloa CA, van Reeuwijk J, Letteboer SJ, Sang L, Giles RH, Liu Q, ... ... Dang CV, et al. Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nature Genetics. 42: 840-50. PMID 20835237 DOI: 10.1038/Ng.662  1
2010 Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio AL, Dias SM, Dang CV, Cerione RA. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell. 18: 207-19. PMID 20832749 DOI: 10.1016/J.Ccr.2010.08.009  1
2010 Dang CV, Day RS, Selwyn B, Maldonado YM, Nguyen KC, Le TD, Le MB. Initiating BMI prevalence studies in Vietnamese children: changes in a transitional economy. Asia Pacific Journal of Clinical Nutrition. 19: 209-16. PMID 20460234  1
2010 Fan JS, Zeller K, Chen YC, Watkins T, Barnes KC, Becker KG, Dang CV, Cheadle C. Time-dependent c-Myc transactomes mapped by array-based nuclear run-on reveal transcriptional modules in human B cells Plos One. 5. PMID 20300622 DOI: 10.1371/Journal.Pone.0009691  1
2010 Iwata T, Schultz D, Hicks J, Hubbard GK, Mutton LN, Lotan TL, Bethel C, Lotz MT, Yegnasubramanian S, Nelson WG, Dang CV, Xu M, Anele U, Koh CM, Bieberich CJ, et al. MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells. Plos One. 5: e9427. PMID 20195545 DOI: 10.1371/Journal.Pone.0009427  1
2010 Le A, Cooper CR, Gouw AM, Dinavahi R, Maitra A, Deck LM, Royer RE, Vander Jagt DL, Semenza GL, Dang CV. Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 107: 2037-42. PMID 20133848 DOI: 10.1073/Pnas.0914433107  1
2010 Yustein JT, Liu YC, Gao P, Jie C, Le A, Vuica-Ross M, Chng WJ, Eberhart CG, Bergsagel PL, Dang CV. Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model. Proceedings of the National Academy of Sciences of the United States of America. 107: 3534-9. PMID 20133585 DOI: 10.1073/Pnas.0901230107  1
2010 Dang CV. p32 (C1QBP) and cancer cell metabolism: Is the Warburg effect a lot of hot air? Molecular and Cellular Biology. 30: 1300-1302. PMID 20100868 DOI: 10.1128/Mcb.01661-09  1
2010 Dang CV. Rethinking the warburg effect with Myc micromanaging glutamine metabolism Cancer Research. 70: 859-862. PMID 20086171 DOI: 10.1158/0008-5472.Can-09-3556  1
2010 Wade JF, Dang CV, Nelson L, Wasserberger J. Emergent Complications of the Newer Anticonvulsants Journal of Emergency Medicine. 38: 231-237. PMID 18762404 DOI: 10.1016/j.jemermed.2008.03.032  1
2010 Koh CM, Bieberich CJ, Dang CV, Nelson WG, Yegnasubramanian S, De Marzo AM. MYC and prostate cancer Genes and Cancer. 1: 617-628. DOI: 10.1177/1947601910379132  1
2010 Dang CV. Enigmatic MYC conducts an unfolding systems biology symphony Genes and Cancer. 1: 526-531. DOI: 10.1177/1947601910378742  1
2010 Le A, Cooper CR, Gouw A, Maitra A, Dinavahi R, Deck L, Royer R, Jagt DV, Semenza G, Dang CV. Abstract 5453: Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression Cancer Research. 70: 5453-5453. DOI: 10.1158/1538-7445.Am10-5453  1
2010 Ricklis RM, Vuica-Ross M, Brodsky RA, Sausville E, Dang CV, Karp JE, Emadi A. Abstract 4539: Anti-leukemic activity of mitochondria-targeted asymmetrical 2,2′-binaphthoquinones Cancer Research. 70: 4539-4539. DOI: 10.1158/1538-7445.Am10-4539  1
2010 Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio ALB, Dias SMG, Dang CV, Cerione RA. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation Cancer Cell. 18: 397. DOI: 10.1016/j.ccr.2010.10.011  1
2009 Dang CV. PKM2 tyrosine phosphorylation and glutamine metabolism signal a different view of the warburg effect Science Signaling. 2: pe75. PMID 19920249 DOI: 10.1126/Scisignal.297Pe75  1
2009 Dang CV. Edging toward New Therapeutics with Cyclin D1 Egl'ng on Cancer Cancer Cell. 16: 361-362. PMID 19878865 DOI: 10.1016/J.Ccr.2009.10.001  1
2009 Dang CV, Le A, Gao P. MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6479-83. PMID 19861459 DOI: 10.1158/1078-0432.Ccr-09-0889  1
2009 Dang CV. Micro-managing and restraining pluripotent stem cells by MYC Embo Journal. 28: 3065-3066. PMID 19844252 DOI: 10.1038/Emboj.2009.293  1
2009 Dang CV. MYC, microRNAs and glutamine addiction in cancers Cell Cycle. 8: 3243-3245. PMID 19806017 DOI: 10.4161/Cc.8.20.9522  1
2009 Ye Z, Zhan H, Mali P, Dowey S, Williams DM, Jang YY, Dang CV, Spivak JL, Moliterno AR, Cheng L. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders Blood. 114: 5473-5480. PMID 19797525 DOI: 10.1182/Blood-2009-04-217406  1
2009 Flögel U, Dang CV. Myoglobin tames tumor growth and spread Journal of Clinical Investigation. 119: 766-768. PMID 19348046 DOI: 10.1172/Jci38796  1
2009 Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT, Dang CV. C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism Nature. 458: 762-765. PMID 19219026 DOI: 10.1038/Nature07823  1
2009 Chang TC, Zeitels LR, Hwang HW, Chivukula RR, Wentzel EA, Dews M, Jung J, Gao P, Dang CV, Beer MA, Thomas-Tikhonenko A, Mendella JT. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation Proceedings of the National Academy of Sciences of the United States of America. 106: 3384-3389. PMID 19211792 DOI: 10.1073/Pnas.0808300106  1
2008 Gao P, Dang CV, Watson J. Unexpected antitumorigenic effect of fenbendazole when combined with supplementary vitamins Journal of the American Association For Laboratory Animal Science. 47: 37-40. PMID 19049251  1
2008 Zhang H, Qian DZ, Tan YS, Lee K, Gao P, Ren YR, Rey S, Hammers H, Chang D, Pili R, Dang CV, Liu JO, Semenza GL. Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth Proceedings of the National Academy of Sciences of the United States of America. 105: 19579-19586. PMID 19020076 DOI: 10.1073/Pnas.0809763105  1
2008 Liu YC, Li F, Handler J, Huang CR, Xiang Y, Neretti N, Sedivy JM, Zeller KI, Dang CV. Global regulation of nucleotide biosynthetic genes by c-Myc. Plos One. 3: e2722. PMID 18628958 DOI: 10.1371/Journal.Pone.0002722  1
2008 Dang CV, Gao P. Muscle Fatigue from Losing Your PHD Cell Metabolism. 7: 191-192. PMID 18316022 DOI: 10.1016/J.Cmet.2008.02.007  1
2008 Dang CV. Antimalarial therapy prevents Myc-induced lymphoma Journal of Clinical Investigation. 118: 15-17. PMID 18097478 DOI: 10.1172/Jci34503  1
2008 Chang TC, Yu D, Lee YS, Wentzel EA, Arking DE, West KM, Dang CV, Thomas-Tikhonenko A, Mendell JT. Widespread microRNA repression by Myc contributes to tumorigenesis Nature Genetics. 40: 43-50. PMID 18066065 DOI: 10.1038/Ng.2007.30  1
2008 Dang CV, Kim JW, Gao P, Yustein J. The interplay between MYC and HIF in cancer Nature Reviews Cancer. 8: 51-56. PMID 18046334 DOI: 10.1038/Nrc2274  1
2007 Dang CV. The interplay between MYC and HIF in the Warburg effect. Ernst Schering Foundation Symposium Proceedings. 35-53. PMID 18811052  1
2007 Kim JW, Gao P, Liu YC, Semenza GL, Dang CV. Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1 Molecular and Cellular Biology. 27: 7381-7393. PMID 17785433 DOI: 10.1128/Mcb.00440-07  1
2007 Gao P, Zhang H, Dinavahi R, Li F, Xiang Y, Raman V, Bhujwalla ZM, Felsher DW, Cheng L, Pevsner J, Lee LA, Semenza GL, Dang CV. HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell. 12: 230-8. PMID 17785204 DOI: 10.1016/J.Ccr.2007.08.004  1
2007 Yustein JT, Dang CV. Biology and treatment of Burkitt's lymphoma Current Opinion in Hematology. 14: 375-381. PMID 17534164 DOI: 10.1097/Moh.0B013E3281Bccdee  1
2007 Zhang H, Gao P, Fukuda R, Kumar G, Krishnamachary B, Zeller KI, Dang CV, Semenza GL. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell. 11: 407-20. PMID 17482131 DOI: 10.1016/J.Ccr.2007.04.001  1
2007 Fukuda R, Zhang H, Kim Jw, Shimoda L, Dang CV, Semenza G. HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells Cell. 129: 111-122. PMID 17418790 DOI: 10.1016/J.Cell.2007.01.047  1
2007 Kim JW, Gao P, Dang CV. Effects of hypoxia on tumor metabolism Cancer and Metastasis Reviews. 26: 291-298. PMID 17415528 DOI: 10.1007/S10555-007-9060-4  1
2007 Anderson TJ, Tchernyshyov I, Diez R, Cole RN, Geman D, Dang CV, Winslow RL. Discovering robust protein biomarkers for disease from relative expression reversals in 2-D DIGE data. Proteomics. 7: 1197-207. PMID 17366473 DOI: 10.1002/Pmic.200600374  1
2007 Juopperi TA, Schuler W, Yuan X, Collector MI, Dang CV, Sharkis SJ. Isolation of Bone Marrow-Derived Stem Cells using Density-Gradient Separation Experimental Hematology. 35: 335-341. PMID 17258082 DOI: 10.1016/J.Exphem.2006.09.014  1
2007 Ghiorghi YK, Zeller KI, Dang CV, Kaminski PA. The c-Myc target gene Rcl (C6orf108) encodes a novel enzyme, deoxynucleoside 5′-monophosphate N-glycosidase Journal of Biological Chemistry. 282: 8150-8156. PMID 17234634 DOI: 10.1074/Jbc.M610648200  1
2006 Zeller KI, Zhao X, Lee CWH, Kuo PC, Yao F, Yustein JT, Hong SO, Orlov YL, Shahab A, How CY, Fu Y, Weng Z, Kuznetsov VA, Sung WK, Ruan Y, ... Dang CV, et al. Global mapping of c-Myc binding sites and target gene networks in human B cells Proceedings of the National Academy of Sciences of the United States of America. 103: 17834-17839. PMID 17093053 DOI: 10.1073/Pnas.0604129103  1
2006 Kim JW, Dang CV. Cancer's molecular sweet tooth and the warburg effect Cancer Research. 66: 8927-8930. PMID 16982728 DOI: 10.1158/0008-5472.Can-06-1501  1
2006 Dang CV, O'Donnell KA, Zeller KI, Nguyen T, Osthus RC, Li F. The c-Myc target gene network Seminars in Cancer Biology. 16: 253-264. PMID 16904903 DOI: 10.1016/J.Semcancer.2006.07.014  1
2006 Deb-Basu D, Karlsson A, Li Q, Dang CV, Felsher DW. MYC can enforce cell cycle transit from G1 to S and G 2 to S, but not mitotic cellular division, independent of p27-mediated inihibition of cyclin E/CDK2 Cell Cycle. 5: 1348-1355. PMID 16760657 DOI: 10.4161/Cc.5.12.2860  1
2006 Li F, Xiang Y, Potter J, Dinavahi R, Dang CV, Lee LA. Conditional deletion of c-myc does not impair liver regeneration Cancer Research. 66: 5608-5612. PMID 16740696 DOI: 10.1158/0008-5472.Can-05-4242  1
2006 Lee LA, Dang CV. Myc target transcriptomes Current Topics in Microbiology and Immunology. 302: 145-167. PMID 16620028 DOI: 10.1007/3-540-32952-8_6  1
2006 Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia Cell Metabolism. 3: 177-185. PMID 16517405 DOI: 10.1016/J.Cmet.2006.02.002  1
2006 O'Donnell KA, Yu D, Zeller KI, Kim JW, Racke F, Thomas-Tikhonenko A, Dang CV. Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis Molecular and Cellular Biology. 26: 2373-2386. PMID 16508012 DOI: 10.1128/Mcb.26.6.2373-2386.2006  1
2006 Stearns D, Chaudhry A, Abel TW, Burger PC, Dang CV, Eberhart CG. c-myc overexpression causes anaplasia in medulloblastoma. Cancer Research. 66: 673-81. PMID 16423996 DOI: 10.1158/0008-5472.Can-05-1580  1
2005 Dang CV, Li F, Lee LA. Could MYC induction of mitochondrial biogenesis be linked to ROS production and genomic instability? Cell Cycle (Georgetown, Tex.). 4: 1465-6. PMID 16205115 DOI: 10.4161/Cc.4.11.2121  1
2005 Dang CV, O'donnell KA, Juopperi T. The great MYC escape in tumorigenesis. Cancer Cell. 8: 177-8. PMID 16169462 DOI: 10.1016/J.Ccr.2005.08.005  1
2005 Osthus RC, Karim B, Prescott JE, Smith BD, McDevitt M, Huso DL, Dang CV. The Myc target gene JPO1/CDCA7 is frequently overexpressed in human tumors and has limited transforming activity in vivo. Cancer Research. 65: 5620-7. PMID 15994934 DOI: 10.1158/0008-5472.Can-05-0536  1
2005 Li F, Wang Y, Zeller KI, Potter JJ, Wonsey DR, O'Donnell KA, Kim JW, Yustein JT, Lee LA, Dang CV. Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Molecular and Cellular Biology. 25: 6225-34. PMID 15988031 DOI: 10.1128/Mcb.25.14.6225-6234.2005  1
2005 O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature. 435: 839-43. PMID 15944709 DOI: 10.1038/Nature03677  1
2005 Barrett JF, Lee LA, Dang CV. Stimulation of Myc transactivation by the TATA binding protein in promoter-reporter assays. Bmc Biochemistry. 6: 7. PMID 15876353 DOI: 10.1186/1471-2091-6-7  1
2005 Chou WC, Chen HY, Yu SL, Cheng L, Yang PC, Dang CV. Arsenic suppresses gene expression in promyelocytic leukemia cells partly through Sp1 oxidation. Blood. 106: 304-10. PMID 15761015 DOI: 10.1182/Blood-2005-01-0241  1
2005 Kim JW, Dang CV. Multifaceted roles of glycolytic enzymes. Trends in Biochemical Sciences. 30: 142-50. PMID 15752986 DOI: 10.1016/J.Tibs.2005.01.005  1
2005 Chou WC, Dang CV. Acute promyelocytic leukemia: recent advances in therapy and molecular basis of response to arsenic therapies. Current Opinion in Hematology. 12: 1-6. PMID 15604884 DOI: 10.1097/01.Moh.0000148552.93303.45  1
2005 Dang CV, Semenza GL. Cancer energy metabolism Drug Discovery Today: Disease Mechanisms. 2. DOI: 10.1016/J.Ddmec.2005.05.039  1
2005 Kim JW, Gardner LB, Dang CV. Oncogenic alterations of metabolism and the Warburg effect Drug Discovery Today: Disease Mechanisms. 2: 233-238. DOI: 10.1016/J.Ddmec.2005.04.001  1
2005 Dang CV, Li F, Lee LA. Could MYC induction of mitochondrial biogenesis be linked to ROS production and genomic instability? Cell Cycle. 4: 1463-1464.  1
2004 Perry ME, Dang CV, Hockenbery D, Moll U. Highlights of the National Cancer Institute Workshop on mitochondrial function and cancer. Cancer Research. 64: 7640-4. PMID 15492294 DOI: 10.1158/0008-5472.Can-04-1991  1
2004 Elkon R, Zeller KI, Linhart C, Dang CV, Shamir R, Shiloh Y. In silico identification of transcriptional regulators associated with c-Myc. Nucleic Acids Research. 32: 4955-61. PMID 15388797 DOI: 10.1093/Nar/Gkh816  1
2004 Kim JW, Zeller KI, Wang Y, Jegga AG, Aronow BJ, O'Donnell KA, Dang CV. Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays. Molecular and Cellular Biology. 24: 5923-36. PMID 15199147 DOI: 10.1128/Mcb.24.13.5923-5936.2004  1
2004 Eberhart CG, Kratz J, Wang Y, Summers K, Stearns D, Cohen K, Dang CV, Burger PC. Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia. Journal of Neuropathology and Experimental Neurology. 63: 441-9. PMID 15198123 DOI: 10.1093/Jnen/63.5.441  1
2004 Chou WC, Jie C, Kenedy AA, Jones RJ, Trush MA, Dang CV. Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 4578-83. PMID 15070760 DOI: 10.1073/Pnas.0306687101  1
2003 Dang CV. Celebrating the physician-scientist. The Journal of Clinical Investigation. 112: S1-2. PMID 14702959  0.01
2003 Gardner LB, Li F, Yang X, Dang CV. Anoxic fibroblasts activate a replication checkpoint that is bypassed by E1a. Molecular and Cellular Biology. 23: 9032-45. PMID 14645516 DOI: 10.1128/Mcb.23.24.9032-9045.2003  1
2003 Peri S, Navarro JD, Amanchy R, Kristiansen TZ, Jonnalagadda CK, Surendranath V, Niranjan V, Muthusamy B, Gandhi TK, Gronborg M, Ibarrola N, Deshpande N, Shanker K, Shivashankar HN, Rashmi BP, ... ... Dang CV, et al. Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Research. 13: 2363-71. PMID 14525934 DOI: 10.1101/Gr.1680803  1
2003 Ulanet DB, Torbenson M, Dang CV, Casciola-Rosen L, Rosen A. Unique conformation of cancer autoantigen B23 in hepatoma: a mechanism for specificity in the autoimmune response. Proceedings of the National Academy of Sciences of the United States of America. 100: 12361-6. PMID 14519847 DOI: 10.1073/Pnas.2035245100  1
2003 Zeller KI, Jegga AG, Aronow BJ, O'Donnell KA, Dang CV. An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets. Genome Biology. 4: R69. PMID 14519204 DOI: 10.1186/Gb-2003-4-10-R69  1
2003 Fan X, Wang Y, Kratz J, Brat DJ, Robitaille Y, Moghrabi A, Perlman EJ, Dang CV, Burger PC, Eberhart CG. hTERT gene amplification and increased mRNA expression in central nervous system embryonal tumors. The American Journal of Pathology. 162: 1763-9. PMID 12759234 DOI: 10.1016/S0002-9440(10)64311-8  1
2003 Haggerty TJ, Zeller KI, Osthus RC, Wonsey DR, Dang CV. A strategy for identifying transcription factor binding sites reveals two classes of genomic c-Myc target sites. Proceedings of the National Academy of Sciences of the United States of America. 100: 5313-8. PMID 12702757 DOI: 10.1073/Pnas.0931346100  1
2003 Johnson SA, Dubeau L, Kawalek M, Dervan A, Schönthal AH, Dang CV, Johnson DL. Increased expression of TATA-binding protein, the central transcription factor, can contribute to oncogenesis. Molecular and Cellular Biology. 23: 3043-51. PMID 12697807 DOI: 10.1128/Mcb.23.9.3043-3051.2003  1
2003 Kenedy AA, Cohen KJ, Loveys DA, Kato GJ, Dang CV. Identification and characterization of the novel centrosome-associated protein CCCAP Gene. 303: 35-46. PMID 12559564 DOI: 10.1016/S0378-1119(02)01141-1  1
2002 Small GW, Chou TY, Dang CV, Orlowski RZ. Evidence for involvement of calpain in c-Myc proteolysis in vivo. Archives of Biochemistry and Biophysics. 400: 151-61. PMID 12054425 DOI: 10.1016/S0003-9861(02)00005-X  1
2002 Wonsey DR, Zeller KI, Dang CV. The c-Myc target gene PRDX3 is required for mitochondrial homeostasis and neoplastic transformation Proceedings of the National Academy of Sciences of the United States of America. 99: 6649-6654. PMID 12011429 DOI: 10.1073/Pnas.102523299  1
2001 Chou WC, Hawkins AL, Barrett JF, Griffin CA, Dang CV. Arsenic inhibition of telomerase transcription leads to genetic instability Journal of Clinical Investigation. 108: 1541-1547. PMID 11714746 DOI: 10.1172/Jci14064  1
2001 Boxer LM, Dang CV. Translocations involving c-myc and c-myc function Oncogene. 20: 5595-5610. PMID 11607812 DOI: 10.1038/Sj.Onc.1204595  1
2001 Zeller KI, Haggerty TJ, Barrett JF, Guo Q, Wonsey DR, Dang CV. Characterization of Nucleophosmin (B23) as a Myc Target by Scanning Chromatin Immunoprecipitation Journal of Biological Chemistry. 276: 48285-48291. PMID 11604407 DOI: 10.1074/Jbc.M108506200  1
2001 Prescott JE, Osthus RC, Lee LA, Lewis BC, Shim H, Barrett JF, Guo Q, Hawkins AL, Griffin CA, Dang CV. A Novel c-Myc-responsive Gene, JP01, Participates in Neoplastic Transformation Journal of Biological Chemistry. 276: 48276-48284. PMID 11598121 DOI: 10.1074/Jbc.M107357200  1
2001 Kuttler F, Amé P, Clark H, Haughey C, Mougin C, Cahn JY, Dang CV, Raffeld M, Fest T. c-myc box II mutations in Burkitt's lymphoma-derived alleles reduce cell-transformation activity and lower response to broad apoptotic stimuli Oncogene. 20: 6084-6094. PMID 11593416 DOI: 10.1038/Sj.Onc.1204827  1
2001 Dang CV. Runner's anemia Journal of the American Medical Association. 286: 714-716. PMID 11495622 DOI: 10.1001/Jama.286.6.714  1
2001 Kim S, Zeller K, Dang CV, Sandgren EP, Lee LA. A strategy to identify differentially expressed genes using representational difference analysis and cDNA arrays Analytical Biochemistry. 288: 141-148. PMID 11152584 DOI: 10.1006/Abio.2000.4900  1
2001 Gardner LB, Li Q, Park MS, Flanagan WM, Semenza GL, Dang CV. Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression Journal of Biological Chemistry. 276: 7919-7926. PMID 11112789 DOI: 10.1074/Jbc.M010189200  1
2000 Lewis BC, Prescott JE, Campbell SE, Shim H, Orlowski RZ, Dang CV. Tumor induction by the c-Myc target genes rcl and lactate dehydrogenase A. Cancer Research. 60: 6178-83. PMID 11085542  1
2000 Guo QM, Malek RL, Kim S, Chiao C, He M, Ruffy M, Sanka K, Lee NH, Dang CV, Liu ET. Identification of c-Myc responsive genes using rat cDNA microarray Cancer Research. 60: 5922-5928. PMID 11085504  1
2000 Kim S, Li Q, Dang CV, Lee LA. Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo Proceedings of the National Academy of Sciences of the United States of America. 97: 11198-11202. PMID 11005843 DOI: 10.1073/Pnas.200372597  1
2000 Osthus RC, Shim H, Kim S, Li Q, Reddy R, Mukherjee M, Xu Y, Wonsey D, Lee LA, Dang CV. Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc Journal of Biological Chemistry. 275: 21797-21800. PMID 10823814 DOI: 10.1074/Jbc.C000023200  1
2000 Hermeking H, Rago C, Schuhmacher M, Li Q, Barrett JF, Obaya AJ, O'Connell BC, Mateyak MK, Tam W, Kohlhuber F, Dang CV, Sedivy JM, Eick D, Vogelstein B, Kinzler KW. Identification of CDK4 as a target of c-MYC. Proceedings of the National Academy of Sciences of the United States of America. 97: 2229-34. PMID 10688915 DOI: 10.1073/Pnas.050586197  1
2000 Barr LF, Campbell SE, Diette GB, Gabrielson EW, Kim S, Shim H, Dang CV. c-Myc suppresses the tumorigenicity of lung cancer cells and down-regulates vascular endothelial growth factor expression. Cancer Research. 60: 143-9. PMID 10646866  1
1999 Dang CV, Resar LMS, Emison E, Kim S, Li Q, Prescott JE, Wonsey D, Zeller K. Function of the c-Myc oncogenic transcription factor Experimental Cell Research. 253: 63-77. PMID 10579912 DOI: 10.1006/Excr.1999.4686  1
1999 Kolligs FT, Hu G, Dang CV, Fearon ER. Neoplastic transformation of RK3E by mutant β-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression Molecular and Cellular Biology. 19: 5696-5706. PMID 10409758 DOI: 10.1128/Mcb.19.8.5696  1
1999 Li Q, Dang CV. c-myc overexpression uncouples DNA replication from mitosis Molecular and Cellular Biology. 19: 5339-5351. PMID 10409725 DOI: 10.1128/Mcb.19.8.5339  1
1999 Dang CV, Semenza GL. Oncogenic alterations of metabolism Trends in Biochemical Sciences. 24: 68-72. PMID 10098401 DOI: 10.1016/S0968-0004(98)01344-9  1
1999 Dang CV, Gerson SL, Litwak M, Padarathsingh M. Gene therapy and translational cancer research. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 5: 471-4. PMID 10037199  1
1999 Fearon ER, Dang CV. Cancer genetics: Tumor suppressor meets oncogene Current Biology. 9: R62-R65. PMID 10021355 DOI: 10.1016/S0960-9822(99)80012-8  1
1999 Dang CV. c-Myc target genes involved in cell growth, apoptosis, and metabolism Molecular and Cellular Biology. 19: 1-11. PMID 9858526 DOI: 10.1128/Mcb.19.1.1  1
1998 Brodsky RA, Petri M, Smith BD, Seifter EJ, Spivak JL, Styler M, Dang CV, Brodsky I, Jones RJ. Immunoablative high-dose cyclophosphamide without stem-cell rescue for refractory, severe autoimmune disease Annals of Internal Medicine. 129: 1031-1035. PMID 9867758 DOI: 10.7326/0003-4819-129-12-199812150-00007  1
1998 Barr LF, Campbell SE, Bochner BS, Dang CV. Association of the decreased expression of α3β1 integrin with the altered cell: Environmental interactions and enhanced soft agar cloning ability of c-myc-overexpressing small cell lung cancer cells Cancer Research. 58: 5537-5545. PMID 9850091  1
1998 Dang CV, Gardner LB. Transient global amnesia after sex [17] Lancet. 352: 1557-1558. PMID 9820339 DOI: 10.1016/S0140-6736(05)60376-5  1
1998 Orlowski RZ, Eswara JR, Lafond-Walker A, Grever MR, Orlowski M, Dang CV. Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor Cancer Research. 58: 4342-4348. PMID 9766662  1
1998 Lin KI, Chattopadhyay N, Bai M, Alvarez R, Dang CV, Baraban JM, Brown EM, Ratan RR. Elevated extracellular calcium can prevent apoptosis via the calcium-sensing receptor. Biochemical and Biophysical Research Communications. 249: 325-31. PMID 9712695 DOI: 10.1006/Bbrc.1998.9124  1
1998 Guo Q, Xie J, Dang CV, Liu ET, Bishop JM. Identification of a large Myc-binding protein that contains RCC1-like repeats. Proceedings of the National Academy of Sciences of the United States of America. 95: 9172-7. PMID 9689053 DOI: 10.1073/Pnas.95.16.9172  1
1998 Walter MJ, Dang CV. Pancytopenia secondary to oxalosis in a 23-year-old woman [6] Blood. 91: 4394. PMID 9596694  1
1998 Shim H, Chun YS, Lewis BC, Dang CV. A unique glucose-dependent apoptotic pathway induced by c-Myc Proceedings of the National Academy of Sciences of the United States of America. 95: 1511-1516. PMID 9465046 DOI: 10.1073/Pnas.95.4.1511  1
1998 Walter MJ, Dang CV. Pancytopenia Secondary to Oxalosis in a 23-Year-Old Woman Blood. 91: 4394-4394. DOI: 10.1182/Blood.V91.11.4394.Spll6_4394_4394  1
1997 Pangilinan F, Li Q, Weaver T, Lewis BC, Dang CV, Spencer F. Mammalian BUB1 protein kinases: Map positions and in vivo expression Genomics. 46: 379-388. PMID 9441741 DOI: 10.1006/Geno.1997.5068  1
1997 Dang CV, Lewis BC, Dolde C, Dang G, Shim H. Oncogenes in tumor metabolism, tumorigenesis, and apoptosis Journal of Bioenergetics and Biomembranes. 29: 345-354. PMID 9387095 DOI: 10.1023/A:1022446730452  1
1997 Wechsler DS, Shelly CA, Petroff CA, Dang CV. MXI1, a putative tumor suppressor gene, suppresses growth of human glioblastoma cells. Cancer Research. 57: 4905-12. PMID 9354456  1
1997 Shim H, Lewis BC, Dolde C, Li Q, Wu CS, Chun YS, Dang CV. Myc target genes in neoplastic transformation Current Topics in Microbiology and Immunology. 224: 181-190. PMID 9308241 DOI: 10.1007/978-3-642-60801-8_18  1
1997 Lee LA, Dang CV. C-Myc transrepression and cell transformation Current Topics in Microbiology and Immunology. 224: 131-135. PMID 9308236 DOI: 10.1007/978-3-642-60801-8_13  1
1997 Lewis BC, Shim H, Li Q, Wu CS, Lee LA, Maity A, Dang CV. Identification of putative c-Myc-responsive genes: Characterization of rcl, a novel growth-related gene Molecular and Cellular Biology. 17: 4967-4978. PMID 9271375 DOI: 10.1128/Mcb.17.9.4967  1
1997 Alvarez RJ, Gips SJ, Moldovan N, Wilhide CC, Milliken EE, Hoang AT, Hruban RH, Silverman HS, Dang CV, Goldschmidt-Clermont PJ. 17β-estradiol inhibits apoptosis of endothelial cells Biochemical and Biophysical Research Communications. 237: 372-381. PMID 9268719 DOI: 10.1006/Bbrc.1997.7085  1
1997 Yano T, Nakamura T, Blechman J, Sorio C, Dang CV, Geiger B, Canaani E. Nuclear punctate distribution of ALL-1 is conferred by distinct elements at the N terminus of the protein Proceedings of the National Academy of Sciences of the United States of America. 94: 7286-7291. PMID 9207083 DOI: 10.1073/Pnas.94.14.7286  1
1997 Shim H, Dolde C, Lewis BC, Wu CS, Dang G, Jungmann RA, Dalla-Favera R, Dang CV. c-Myc transactivation of LDH-A: Implications for tumor metabolism and growth Proceedings of the National Academy of Sciences of the United States of America. 94: 6658-6663. PMID 9192621 DOI: 10.1073/Pnas.94.13.6658  1
1997 Cañelles M, Delgado MD, Hyland KM, Lerga A, Richard C, Dang CV, León J. Max and inhibitory c-Myc mutants induce erythroid differentiation and resistance to apoptosis in human myeloid leukemia cells Oncogene. 14: 1315-1327. PMID 9178892  1
1997 Dang CV, Lewis BC. Role of oncogenic transcription factor c-Myc in cell cycle regulation, apoptosis and metabolism Journal of Biomedical Science. 4: 269-278. DOI: 10.1007/Bf02258350  1
1996 Wechsler DS, Shelly CA, Dang CV. Genomic organization of human MXI1, a putative tumor suppressor gene. Genomics. 32: 466-70. PMID 8838813 DOI: 10.1006/Geno.1996.0144  1
1996 Cohen KJ, Hanna JS, Prescott JE, Dang CV. Transformation by the Bmi-1 oncoprotein correlates with its subnuclear localization but not its transcriptional suppression activity Molecular and Cellular Biology. 16: 5527-5535. PMID 8816465 DOI: 10.1128/Mcb.16.10.5527  1
1996 Semmes OJ, Barrett JF, Dang CV, Jeang KT. Human T-cell leukemia virus type I Tax masks c-Myc function through a cAMP-dependent pathway Journal of Biological Chemistry. 271: 9730-9738. PMID 8621651 DOI: 10.1074/Jbc.271.16.9730  1
1996 Lee LA, Dolde C, Barrett J, Wu CS, Dang CV. A link between c-Myc-mediated transcriptional repression and neoplastic transformation Journal of Clinical Investigation. 97: 1687-1695. PMID 8601634 DOI: 10.1172/Jci118595  1
1996 Lee LA, Dolde C, Wu CS, Barrett J, Dang CV. C-myc transcriptional repression is linked to cell transformation Journal of Investigative Medicine. 44: 237a.  1
1995 Mol PC, Wang RH, Batey DW, Lee LA, Dang CV, Berger SL. Do products of the myc proto-oncogene play a role in transcriptional regulation of the prothymosin α gene? Molecular and Cellular Biology. 15: 6999-7009. PMID 8524267  1
1995 Wang HD, Yuh CH, Dang CV, Johnson DL. The hepatitis B virus X protein increases the cellular level of TATA-binding protein, which mediates transactivation of RNA polymerase III genes Molecular and Cellular Biology. 15: 6720-6728. PMID 8524237 DOI: 10.1128/Mcb.15.12.6720  1
1995 Lee LA, Resar LMS, Dang CV. Cell density and paradoxical transcriptional properties of c-Myc and Max in cultured mouse fibroblasts Journal of Clinical Investigation. 95: 900-904. PMID 7860774 DOI: 10.1172/Jci117741  1
1995 Chou TY, Dang CV, Hart GW. Glycosylation of the c-Myc transactivation domain Proceedings of the National Academy of Sciences of the United States of America. 92: 4417-4421. PMID 7753821 DOI: 10.1073/Pnas.92.10.4417  1
1995 Chou TY, Hart GW, Dang CV. c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas Journal of Biological Chemistry. 270: 18961-18965. PMID 7642555 DOI: 10.1074/Jbc.270.32.18961  1
1995 Hoang AT, Lutterbach B, Lewis BC, Yano T, Chou TY, Barrett JF, Raffeld M, Hann SR, Dang CV. A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-myc transactivation domain Molecular and Cellular Biology. 15: 4031-4042. PMID 7623799 DOI: 10.1128/Mcb.15.8.4031  1
1995 Barrett JF, Lewis BC, Hoang AT, Alvarez RJ, Dang CV. Cyclin A links c-Myc to adhesion-independent cell proliferation Journal of Biological Chemistry. 270: 15923-15925. PMID 7608142 DOI: 10.1074/Jbc.270.27.15923  1
1994 Wechsler DS, Papoulas O, Dang CV, Kingston RE. Differential binding of c-Myc and Max to nucleosomal DNA. Molecular and Cellular Biology. 14: 4097-107. PMID 8196648 DOI: 10.1128/Mcb.14.6.4097  1
1994 Gu W, Bhatia K, Magrath IT, Dang CV, Dalla-Favera R. Binding and suppression of the Myc transcriptional activation domain by p107 Science. 264: 251-254. PMID 8146655 DOI: 10.1126/Science.8146655  1
1994 Hoang AT, Cohen KJ, Barrett JF, Bergstrom DA, Dang CV. Participation of cyclin A in Myc-induced apoptosis Proceedings of the National Academy of Sciences of the United States of America. 91: 6875-6879. PMID 8041712 DOI: 10.1073/Pnas.91.15.6875  1
1994 Wechsler DS, Hawkins AL, Li X, Jabs EW, Griffin CA, Dang CV. Localization of the human Mxi1 transcription factor gene (MXI1) to chromosome 10q24-q25. Genomics. 21: 669-72. PMID 7959753 DOI: 10.1006/Geno.1994.1336  1
1994 Navankasattusas S, Sawadogo M, Van Bilsen M, Dang CV, Chien KR. The basic helix-loop-helix protein upstream stimulating factor regulates the cardiac ventricular myosin light-chain 2 gene via independent cis regulatory elements Molecular and Cellular Biology. 14: 7331-7339. PMID 7935447 DOI: 10.1128/Mcb.14.11.7331  1
1994 Raffeld M, Yano T, Hoang AT, Lewis B, Clark HM, Otsuki T, Dang CV. Clustered mutations in the transcriptional activation domain of Myc in 8q24 translocated lymphomas and their functional consequences Current Topics in Microbiology and Immunology. 194: 265-272. PMID 7895498 DOI: 10.1007/978-3-642-79275-5_31  1
1993 Resar LMS, Dolde C, Barrett JF, Dang CV. B-Myc Inhibits Neoplastic Transformation and Transcriptional Activation by c-Myc Molecular and Cellular Biology. 13: 1130-1136. PMID 8423780 DOI: 10.1128/Mcb.13.2.1130  1
1993 Finkel T, Duc J, Fearon ER, Dang CV, Tomaselli GF. Detection and modulation in vivo of helix-loop-helix protein-protein interactions Journal of Biological Chemistry. 268: 5-8. PMID 8380166  1
1992 Dang CV, Dolde C, Gillison ML, Kato GJ. Discrimination between related DNA sites by a single amino acid residue of Myc-related basic-helix-loop-helix proteins Proceedings of the National Academy of Sciences of the United States of America. 89: 599-602. PMID 1731330 DOI: 10.1073/Pnas.89.2.599  1
1992 Kato GJ, Lee WMF, Chen L, Dang CV. Max: Functional domains and interaction with c-Myc Genes and Development. 6: 81-92. PMID 1730412 DOI: 10.1101/Gad.6.1.81  1
1992 Barrett J, Birrer MJ, Kato GJ, Dosaka-Akita H, Dang CV. Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells Molecular and Cellular Biology. 12: 3130-3137. PMID 1620120 DOI: 10.1128/Mcb.12.7.3130  1
1992 Kato GJ, Dang CV. Function of the c-Myc oncoprotein Faseb Journal. 6: 3065-3072. PMID 1521738 DOI: 10.1096/Fasebj.6.12.1521738  1
1992 Kato GJ, Wechsler DS, Dang CV. DNA binding by the Myc oncoproteins. Cancer Treatment and Research. 63: 313-25. PMID 1363364 DOI: 10.1007/978-1-4615-3088-6_16  1
1992 Wechsler DS, Dang CV. Opposite orientations of DNA bending by c-Myc and Max. Proceedings of the National Academy of Sciences of the United States of America. 89: 7635-9. PMID 1323849 DOI: 10.1073/Pnas.89.16.7635  1
1991 Dang CV, Barrett J, Villa-Garcia M, Resar LMS, Kato GJ, Fearon ER. Intracellular Leucine Zipper Interactions Suggest c-Myc Hetero-Oligomerization Molecular and Cellular Biology. 11: 954-962. PMID 1990293 DOI: 10.1128/Mcb.11.2.954  1
1991 Dang CV. c-Myc oncoprotein function Bba - Reviews On Cancer. 1072: 103-113. PMID 1751543 DOI: 10.1016/0304-419X(91)90009-A  1
1990 Kato GJ, Barrett J, Villa-Garcia M, Dang CV. An amino-terminal c-Myc domain required for neoplastic transformation activates transcription Molecular and Cellular Biology. 10: 5914-5920. PMID 2233723 DOI: 10.1128/Mcb.10.11.5914  1
1989 LaDuca FM, Tinsley LA, Dang CV, Bell WR. Stimulation of fibrinogen synthesis in cultured rat hepatocytes by fibrinogen degradation product fragment D Proceedings of the National Academy of Sciences of the United States of America. 86: 8788-8792. PMID 2813424 DOI: 10.1073/Pnas.86.22.8788  1
1989 Dang CV, Bell WR, Shuman M. The normal and morbid biology of fibrinogen The American Journal of Medicine. 87: 567-576. PMID 2683767 DOI: 10.1016/S0002-9343(89)80616-3  1
1989 Dang CV, Van Dam H, Buckmire M, Lee WMF. DNA-binding domain of human c-myc produced in Escherichia coli Molecular and Cellular Biology. 9: 2477-2486. PMID 2668734 DOI: 10.1128/Mcb.9.6.2477  1
1989 Dang CV, McGuire M, Buckmire M, Lee WMF. Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein Nature. 337: 664-666. PMID 2645525 DOI: 10.1038/337664A0  1
1989 Dang CV. Oncogenes and proto-oncogenes: General concepts Cancer Treatment and Research. 47: 1-24. DOI: 10.1007/978-1-4613-1599-5_1  0.01
1988 Dang CV, LaDuca FM, Bell WR. Heparin requirement for the quantitation of fibrinogen production by primary hepatocyte cultures Analytical Biochemistry. 170: 456-462. PMID 3394944 DOI: 10.1016/0003-2697(88)90658-6  1
1988 Dang CV. Detection and use of recombinant staphylococcal protein A fusion proteins to localize nucleic-acid-binding domains of proteins Analytical Biochemistry. 174: 313-317. PMID 3064652 DOI: 10.1016/0003-2697(88)90551-9  1
1988 Dang CV, Lee WMF. Identification of the human c-myc protein nuclear translocation signal Molecular and Cellular Biology. 8: 4048-4054. PMID 3054508 DOI: 10.1128/Mcb.8.10.4048  1
1988 Dang CV, Tan EM, Traugh JA. Myositis autoantibody reactivity and catalytic function of threonyl-tRNA synthetase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2: 2376-9. PMID 2452112 DOI: 10.1096/Fasebj.2.8.2452112  1
1986 Dang CV, LaDuca FM, Bell WR. Histidyl-tRNA synthetase, the myositis Jo-1 antigen, is cytoplasmic and unassociated with the cytoskeletal framework Experimental Cell Research. 164: 261-266. PMID 3956597 DOI: 10.1016/0014-4827(86)90474-X  1
1986 LaDuca FM, Dang CV, Bell WR. Application of a nitrocellulose immunoassay for quantitation of proteins secreted in culture media Analytical Biochemistry. 158: 262-267. PMID 3812970 DOI: 10.1016/0003-2697(86)90547-6  1
1986 Dang CV. Multienzyme complex of aminoacyl-tRNA synthetases: an essence of being eukaryotic Biochemical Journal. 239: 249-255. PMID 3545179 DOI: 10.1042/Bj2390249  1
1986 Dang CV. Higher eukaryotic aminoacyl-tRNA synthetases in physiologic and pathologic states Molecular and Cellular Biochemistry. 71: 107-120. PMID 3534543 DOI: 10.1007/Bf00214769  1
1985 Dang CV, Bell WR, Kaiser D, Wong A. Disorganization of cultured vascular endothelial cell monolayers by fibrinogen fragment D Science. 227: 1487-1490. PMID 4038818 DOI: 10.1126/Science.4038818  1
1985 Dang CV, Ferguson B, Burke DJ, Garcia V, Yang DCH. Interactions of aminoacyl-tRNA synthetases in high-molecular-weight multienzyme complexes from rat liver Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 829: 319-326. PMID 4005265 DOI: 10.1016/0167-4838(85)90239-0  1
1985 Dang CV, Stein PH, Gress DR, Dallabetta GA, Bender WL. A case of agnogenic myeloid metaplasia evolving into acute myelogenous leukemia associated with the development of trisomy 11 in bone marrow cells American Journal of Hematology. 19: 285-288. PMID 3860004 DOI: 10.1002/Ajh.2830190311  1
1985 Dang CV, Bell WR, Ebert RF, Starksen NF. Protective effect of divalent cations in the plasmin degradation of fibrinogen Archives of Biochemistry and Biophysics. 238: 452-457. PMID 3158281 DOI: 10.1016/0003-9861(85)90186-9  1
1985 Dang CV, Schlott W, Watson AJS, Gimenez L, Klassen DK. Horseshoe kidney and renovascular hypertension responsive to percutaneous transluminal angioplasty Annals of Internal Medicine. 102: 70-71. PMID 3155600 DOI: 10.7326/0003-4819-102-1-70  1
1985 Dang CV. Intranuclear location of the myositis-specific Jo-1 antigen: hopping histidyl-tRNA synthetase? Arthritis and Rheumatism. 28: 839-840. PMID 2409986 DOI: 10.1002/art.1780280724  1
1984 Dang CV. Identity of the ubiquitous eukaryotic ring-shaped miniparticle Cell Biology International Reports. 8: 323-327. PMID 6733790 DOI: 10.1016/0309-1651(84)90159-0  1
1984 Yang DCH, Dang CV, Arnett FC. Rat liver histidyl-tRNA synthetase. Purification and inhibition by the myositis-specific anti-Jo-1 autoantibody Biochemical and Biophysical Research Communications. 120: 15-21. PMID 6712685 DOI: 10.1016/0006-291X(84)91407-4  1
1983 Dang CV. Multienzyme complexes of eukaryotic aminoacyl-tRNA synthetases Bioscience Reports. 3: 527-538. PMID 12033399 DOI: 10.1007/Bf01120696  1
1983 Dang CV. Hydrodynamic properties and structure of the rat liver 12 S arginyl- and lysyl-tRNA synthetase complex Biochemical and Biophysical Research Communications. 117: 464-469. PMID 6661237 DOI: 10.1016/0006-291X(83)91223-8  1
1983 Dang CV, Yang DCH, Pollard TD. Association of methionyl-tRNA synthetase with detergent-insoluble components of the rough endoplasmic reticulum Journal of Cell Biology. 96: 1138-1147. PMID 6339526 DOI: 10.1083/Jcb.96.4.1138  1
1982 Dang CV. High molecular weight complex formation of rat liver lysyl-tRNA synthetase reduces enzyme lability to thermal inactivation Biochemical and Biophysical Research Communications. 106: 44-47. PMID 7103987 DOI: 10.1016/0006-291X(82)92055-1  1
1982 Dang CV, Yang DCH. High molecular weight complexes of eukaryotic aminoacyl-trna synthetases International Journal of Biochemistry. 14: 539-543. PMID 7049785 DOI: 10.1016/0020-711X(82)90030-1  1
1982 Dang CV, Johnson DL, Yang DCH. High molecular mass amino acyl-tRNA synthetase complexes in eukaryotes Febs Letters. 142: 1-6. PMID 7049726 DOI: 10.1016/0014-5793(82)80206-8  1
1981 Dang CV. Tobacco-alcohol amblyopia: A proposed biochemical basis for pathogenesis Medical Hypotheses. 7: 1317-1328. PMID 7033739 DOI: 10.1016/0306-9877(81)90122-5  1
1978 Dang CV, Yang DCH. Affinity chromatography of rat liver aminoacyl-tRNA synthetase complex Biochemical and Biophysical Research Communications. 80: 709-714. PMID 637862 DOI: 10.1016/0006-291X(78)91302-5  1
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