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393 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Fei DL, Zhen T, Durham B, Ferrarone J, Zhang T, Garrett L, Yoshimi A, Abdel-Wahab O, Bradley RK, Liu P, Varmus H. Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene . Proceedings of the National Academy of Sciences of the United States of America. PMID 30322915 DOI: 10.1073/Pnas.1812669115  0.32
2018 Fan PD, Narzisi G, Jayaprakash AD, Venturini E, Robine N, Smibert P, Germer S, Yu HA, Jordan EJ, Paik PK, Janjigian YY, Chaft JE, Wang L, Jungbluth AA, Middha S, ... ... Varmus H, et al. amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics. Proceedings of the National Academy of Sciences of the United States of America. PMID 29875142 DOI: 10.1073/Pnas.1717782115  0.32
2018 Unni AM, Harbourne B, Oh MH, Wild S, Ferrarone JR, Lockwood WW, Varmus H. Author response: Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells Elife. DOI: 10.7554/Elife.33718.022  0.6
2016 Fei DL, Motowski H, Chatrikhi R, Prasad S, Yu J, Gao S, Kielkopf CL, Bradley RK, Varmus H. Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival. Plos Genetics. 12: e1006384. PMID 27776121 DOI: 10.1371/Journal.Pgen.1006384  0.32
2016 McFadden DG, Politi K, Bhutkar A, Chen FK, Song X, Pirun M, Santiago PM, Kim-Kiselak C, Platt JT, Lee E, Hodges E, Rosebrock AP, Bronson RT, Socci ND, Hannon GJ, ... ... Varmus H, et al. Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 27702896 DOI: 10.1073/Pnas.1613601113  1
2016 Zhen T, Fei DL, Zhao L, Lopez G, Varmus H, Liu PP. Runx1 Deficiency and MDS-Associated U2af1 Mutation Cooperate for Leukemia Development in a New Mouse Model Blood. 128: 964-964. DOI: 10.1182/Blood.V128.22.964.964  0.6
2016 Fei D, Motowski H, Prasad S, Yu J, Bradley R, Varmus H. Abstract 4163: Molecular and physiological effects of splicing factor mutant U2AF1 in human lung cell lines and in mice Cancer Research. 76: 4163-4163. DOI: 10.1158/1538-7445.Am2016-4163  0.6
2015 Maity TK, Venugopalan A, Linnoila I, Cultraro CM, Giannakou A, Nemati R, Zhang X, Webster JD, Ritt D, Ghosal S, Hoschuetzky H, Simpson RM, Biswas R, Politi K, Morrison DK, ... Varmus HE, et al. Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma. Cancer Discovery. 5: 534-49. PMID 25735773 DOI: 10.1158/2159-8290.CD-14-0750  0.32
2015 Collins FS, Varmus H. A new initiative on precision medicine New England Journal of Medicine. 372: 793-795. PMID 25635347 DOI: 10.1056/Nejmp1500523  1
2015 Song X, Fan PD, Bantikassegn A, Guha U, Threadgill DW, Varmus H, Politi K. ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas. Cancer Research. 75: 1035-45. PMID 25596284 DOI: 10.1158/0008-5472.Can-13-1625  0.32
2015 Abrams J, Kramer B, Doroshow JH, Varmus H. National Cancer Institute-supported clinical trials networks. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 293. PMID 25452448 DOI: 10.1200/Jco.2014.59.5421  1
2015 Unni AM, Lockwood WW, Zejnullahu K, Lee-Lin S, Varmus H. Author response: Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma Elife. DOI: 10.7554/Elife.06907.015  0.6
2015 Unni AM, Lockwood WW, Zejnullahu K, Lee-Lin SQ, Varmus H. Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma Elife. 4: 1-23. DOI: 10.7554/Elife.06907  1
2015 Varmus H. Abstract A39: Initial characterization of genetically engineered mice carrying a conditional allele of a splicing factor gene (U2AF1) commonly mutated in myeloid disorders. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A39  0.6
2014 Alberts B, Kirschner MW, Tilghman S, Varmus H. Rescuing US biomedical research from its systemic flaws. Proceedings of the National Academy of Sciences of the United States of America. 111: 5773-7. PMID 24733905 DOI: 10.1073/Pnas.1404402111  1
2014 de Bruin EC, Cowell C, Warne PH, Jiang M, Saunders RE, Melnick MA, Gettinger S, Walther Z, Wurtz A, Heynen GJ, Heideman DA, Gómez-Román J, García-Castaño A, Gong Y, Ladanyi M, ... Varmus H, et al. Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer. Cancer Discovery. 4: 606-19. PMID 24535670 DOI: 10.1158/2159-8290.Cd-13-0741  1
2013 Berger AH, Chen M, Morotti A, Janas JA, Niki M, Bronson RT, Taylor BS, Ladanyi M, Van Aelst L, Politi K, Varmus HE, Pandolfi PP. DOK2 inhibits EGFR-mutated lung adenocarcinoma. Plos One. 8: e79526. PMID 24255704 DOI: 10.1371/Journal.Pone.0079526  1
2013 Varmus H, Kumar HS. Addressing the growing international challenge of cancer: A multinational perspective Science Translational Medicine. 5. PMID 23467558 DOI: 10.1126/Scitranslmed.3005899  1
2013 Sacco RL, Smith SC, Holmes D, Shurin S, Brawley O, Cazap E, Glass R, Komajda M, Koroshetz W, Mayer-Davis E, Mbanya JC, Sledge G, Varmus H. Accelerating progress on non-communicable diseases The Lancet. 382: e4-e5. PMID 21933747 DOI: 10.1016/S0140-6736(11)61477-3  1
2013 Song X, Fan P, Guha U, Threadgill D, Varmus H, Politi K. Abstract C113: ERBB3 independent activation of the PI3K pathway in EGFR mutant lung adenocarcinomas. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C113  0.6
2012 Lockwood WW, Zejnullahu K, Bradner JE, Varmus H. Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins Proceedings of the National Academy of Sciences of the United States of America. 109: 19408-19413. PMID 23129625 DOI: 10.1073/Pnas.1216363109  1
2012 Nusse R, Varmus H. Three decades of Wnts: a personal perspective on how a scientific field developed. The Embo Journal. 31: 2670-84. PMID 22617420 DOI: 10.1038/Emboj.2012.146  1
2012 Varmus H, Harlow E. Science funding: Provocative questions in cancer research. Nature. 481: 436-7. PMID 22281578 DOI: 10.1038/481436A  1
2012 Beverly LJ, Lockwood WW, Shah PP, Erdjument-Bromage H, Varmus H. Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1 Proceedings of the National Academy of Sciences of the United States of America. 109: E119-E126. PMID 22233804 DOI: 10.1073/Pnas.1119167109  1
2012 Bruin Ed, Cowell C, Howell M, Varmus H, Politi K, Downward J. Abstract A18: Reduced NF1 expression in resistance to EGF receptor inhibitory drugs in lung adenocarcinoma Clinical Cancer Research. 18. DOI: 10.1158/1078-0432.Mechres-A18  0.6
2012 Varmus H. Arlen Specter: A retrospective Proceedings of the National Academy of Sciences of the United States of America. 109: 21178-21179. DOI: 10.1073/Pnas.1219606110  1
2012 Atlas R, Campbell P, Cozzarelli NR, Curfman G, Enquist L, Fink G, Flanagin A, Fletcher J, George E, Hammes G, Heyman D, Inglesby T, Kaplan S, Kennedy D, Krug J, ... ... Varmus H, et al. Uncensored exchange of scientific results (Proceedings of the National Academy of Sciences (2003) 100, 4, (1464) DOI: 10.1073/pnas.0630491100) Proceedings of the National Academy of Sciences of the United States of America. 109: 8352. DOI: 10.1073/Pnas.1206993109  1
2011 Cohen JI, Fauci AS, Varmus H, Nabel GJ. Epstein-Barr virus: an important vaccine target for cancer prevention. Science Translational Medicine. 3: 107fs7. PMID 22049067 DOI: 10.1126/Scitranslmed.3002878  1
2011 Du YCN, Chou CK, Klimstra DS, Varmus H. Receptor for hyaluronan-mediated motility isoform B promotes liver metastasis in a mouse model of multistep tumorigenesis and a tail vein assay for metastasis Proceedings of the National Academy of Sciences of the United States of America. 108: 16753-16758. PMID 21940500 DOI: 10.1073/Pnas.1114022108  1
2011 Varmus H, Trimble EL. Integrating cancer control into global health Science Translational Medicine. 3. PMID 21937755 DOI: 10.1126/Scitranslmed.3002321  1
2011 Somwar R, Erdjument-Bromage H, Larsson E, Shum D, Lockwood WW, Yang G, Sander C, Ouerfelli O, Tempst PJ, Djaballah H, Varmus HE. Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines. Proceedings of the National Academy of Sciences of the United States of America. 108: 16375-80. PMID 21930909 DOI: 10.1073/Pnas.1113554108  1
2011 Taguchi A, Politi K, Pitteri SJ, Lockwood WW, Faça VM, Kelly-Spratt K, Wong CH, Zhang Q, Chin A, Park KS, Goodman G, Gazdar AF, Sage J, Dinulescu DM, Kucherlapati R, ... ... Varmus HE, et al. Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. Cancer Cell. 20: 289-99. PMID 21907921 DOI: 10.1016/J.Ccr.2011.08.007  1
2011 Varmus H. Newsmaker interview: Harold Varmus. Piloting cancer research with a shrinking budget. Interview by Jocelyn Kaiser Science (New York, N.Y.). 333: 397. PMID 21778374 DOI: 10.1126/science.333.6041.397  1
2011 Varmus H. NIH cancer chief wants more with less: by Meredith Wadman Nature. 475: 18. PMID 21734681 DOI: 10.1038/475018a  1
2011 Bruin ECd, Cowell CF, Howell M, Varmus HE, Politi K, Downward J. Abstract LB-398: Identification of novel mechanisms of resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-398  0.32
2011 Taguchi A, Politi K, Pitteri SJ, Lockwood WW, Faça VM, Sage J, Kemp CJ, Varmus HE, Hanash SM. Abstract 3166: Lung cancer bio-signatures in plasma based on the analysis of mouse models Cancer Research. 71: 3166-3166. DOI: 10.1158/1538-7445.Am2011-3166  0.32
2010 Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, Shah K, Socci ND, Weir BA, Ho A, Chiang DY, Reva B, Mermel CH, Getz G, Antipin Y, ... ... Varmus HE, et al. Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nature Genetics. 42: 715-21. PMID 20601955 DOI: 10.1038/Ng.619  1
2010 Varmus H. Ten years on - The human genome and medicine New England Journal of Medicine. 362: 2028-2029. PMID 20505183 DOI: 10.1056/Nejme0911933  1
2010 Politi K, Fan PD, Shen R, Zakowski M, Varmus H. Erlotinib resistance in mouse models of epidermal growth factor receptor-induced lung adenocarcinoma. Disease Models & Mechanisms. 3: 111-9. PMID 20007486 DOI: 10.1242/Dmm.003681  1
2010 McFadden DG, Xuan Z, Rosebrock A, Politi K, Santiago P, Hodges E, Winslow M, Hiramatsu N, Pirun M, Crowley D, Bronson R, Socci N, Varmus H, Hannon G, Jacks T. Abstract LB-151: Targeted gene resequencing in a K-ras-dependent mouse model of metastatic lung adenocarcinoma Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-151  1
2009 Somwar R, Shum D, Djaballah H, Varmus H. Identification and preliminary characterization of novel small molecules that inhibit growth of human lung adenocarcinoma cells Journal of Biomolecular Screening. 14: 1176-1184. PMID 19887599 DOI: 10.1177/1087057109350919  1
2009 Du YCN, Klimstra DS, Varmus H. Activation of PyMT in β cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors Plos One. 4. PMID 19812721 DOI: 10.1371/Journal.Pone.0006932  1
2009 Jechlinger M, Podsypanina K, Varmus H. Regulation of transgenes in three-dimensional cultures of primary mouse mammary cells demonstrates oncogene dependence and identifies cells that survive deinduction Genes and Development. 23: 1677-1688. PMID 19605689 DOI: 10.1101/Gad.1801809  1
2009 Gottfried K, Varmus H. The enlightenment returns. Science (New York, N.Y.). 323: 1538. PMID 19299588 DOI: 10.1126/Science.1173563  1
2009 Asimakopoulos F, Varmus HE. Cell-specific transduction of Prdm1-expressing lineages mediated by a receptor for avian leukosis virus subgroup B. Journal of Virology. 83: 4835-43. PMID 19279099 DOI: 10.1128/Jvi.02254-08  1
2009 Beverly LJ, Varmus HE. MYC-induced myeloid leukemogenesis is accelerated by all six members of the antiapoptotic BCL family. Oncogene. 28: 1274-9. PMID 19137012 DOI: 10.1038/Onc.2008.466  1
2009 Varmus HE, Vogt PK, Bishop JM. Erratum: The Classic: Integration of Deoxyribonucleic Acid Specific for Rous Sarcoma Virus after Infection of Permissive and Nonpermissive Hosts Clinical Orthopaedics and Related Research®. 467: 1927-1927. DOI: 10.1007/s11999-009-0905-8  0.4
2009 Varmus H. Science publishing and science libraries in the internet age Proceedings of the American Philosophical Society. 153: 160-184.  1
2008 Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, ... ... Varmus HE, et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature. 455: 1069-75. PMID 18948947 DOI: 10.1038/Nature07423  1
2008 Guha U, Chaerkady R, Marimuthu A, Patterson AS, Kashyap MK, Harsha HC, Sato M, Bader JS, Lash AE, Minna JD, Pandey A, Varmus HE. Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS. Proceedings of the National Academy of Sciences of the United States of America. 105: 14112-7. PMID 18776048 DOI: 10.1073/Pnas.0806158105  1
2008 Podsypanina K, Du YCN, Jechlinger M, Beverly LJ, Hambardzumyan D, Varmus H. Seeding and propagation of untransformed mouse mammary cells in the lung Science. 321: 1841-1844. PMID 18755941 DOI: 10.1126/Science.1161621  1
2008 Varmus HE, Vogt PK, Bishop JM. The classic: integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts: (RNA tumor viruses/reassociation kinetics/duck cells). 1973. Clinical Orthopaedics and Related Research. 466: 2031-8. PMID 18597148 DOI: 10.1007/s11999-008-0355-8  1
2008 Varmus H. Harold Varmus. Interview by Errol C. Friedberg Nature Reviews. Molecular Cell Biology. 9: 502-503. PMID 18578058 DOI: 10.1038/Nrm2435  1
2008 Varmus H. NIH funds support more than a researcher's own lab Nature. 452: 811. PMID 18421329 DOI: 10.1038/452811B  1
2008 Varmus H. Progress toward public access to science Plos Biology. 6: 657-658. PMID 18399723 DOI: 10.1371/Journal.Pbio.0060101  1
2008 Podsypanina K, Politi K, Beverly LJ, Varmus HE. Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras. Proceedings of the National Academy of Sciences of the United States of America. 105: 5242-7. PMID 18356293 DOI: 10.1073/Pnas.0801197105  1
2008 Bishop JM, Hanahan D, Tlsty T, Hunter T, Lowe S, Varmus H, Dornbush KT, Waring JF, Jacks T, Gilmer T, Sherman M, Gerritsen W, Curran T, Doroshow J, Barrett JC, et al. The 20th Aspen Cancer Conference: Mechanisms of Toxicity, Carcinogenesis, Cancer Prevention, and Cancer Therapy 2005 Molecular Carcinogenesis. 47: 707-732. PMID 18286481 DOI: 10.1002/mc.20214  1
2007 Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, ... ... Varmus HE, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature. 450: 893-8. PMID 17982442 DOI: 10.1038/Nature06358  1
2007 Du YC, Lewis BC, Hanahan D, Varmus H. Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion. Plos Biology. 5: e276. PMID 17941720 DOI: 10.1371/Journal.Pbio.0050276  1
2007 Marks JL, McLellan MD, Zakowski MF, Lash AE, Kasai Y, Broderick S, Sarkaria IS, Pham D, Singh B, Miner TL, Fewell GA, Fulton LL, Mardis ER, Wilson RK, Kris MG, ... ... Varmus H, et al. Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4. Plos One. 2: e426. PMID 17487277 DOI: 10.1371/Journal.Pone.0000426  1
2006 Du Z, Podsypanina K, Huang S, McGrath A, Toneff MJ, Bogoslovskaia E, Zhang X, Moraes RC, Fluck M, Allred DC, Lewis MT, Varmus HE, Li Y. Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models. Proceedings of the National Academy of Sciences of the United States of America. 103: 17396-401. PMID 17090666 DOI: 10.1073/Pnas.0608607103  1
2006 Varmus H. The new era in cancer research Science. 312: 1162-1165. PMID 16728627 DOI: 10.1126/Science.1126758  1
2006 Politi K, Zakowski MF, Fan PD, Schonfeld EA, Pao W, Varmus HE. Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors. Genes & Development. 20: 1496-510. PMID 16705038 DOI: 10.1101/Gad.1417406  1
2006 Bishop JM, Varmus H. Re-aim blame for NIH's hard times. Science (New York, N.Y.). 312: 499. PMID 16645053 DOI: 10.1126/Science.1128904  1
2006 Varmus H. Time for a global science corps Scientist. 20: 24.  1
2005 Pao W, McLellan MD, Pham DK, Singh B, Rusch VW, Zakowski MF, Miller VA, Kris MG, Wilson RK, Varmus HE. Mutational profiling of the oncogenome in non-small cell lung cancer (NSCLC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 7021. PMID 27944458 DOI: 10.1200/Jco.2005.23.16_Suppl.7021  0.48
2005 Varmus H, Pao W, Politi K, Podsypanina K, Du YCN. Oncogenes come of age Cold Spring Harbor Symposia On Quantitative Biology. 70: 1-9. PMID 16869733 DOI: 10.1101/Sqb.2005.70.039  1
2005 Varmus H, Stillman B. Support for the human cancer genome project [1] Science. 310: 1615. PMID 16339428 DOI: 10.1126/Science.310.5754.1615B  1
2005 Huang S, Li Y, Chen Y, Podsypanina K, Chamorro M, Olshen AB, Desai KV, Tann A, Petersen D, Green JE, Varmus HE. Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice. Genome Biology. 6: R84. PMID 16207355 DOI: 10.1186/Gb-2005-6-10-R84  1
2005 Carter TA, Wodicka LM, Shah NP, Velasco AM, Fabian MA, Treiber DK, Milanov ZV, Atteridge CE, Biggs WH, Edeen PT, Floyd M, Ford JM, Grotzfeld RM, Herrgard S, Insko DE, ... ... Varmus H, et al. Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases. Proceedings of the National Academy of Sciences of the United States of America. 102: 11011-6. PMID 16046538 DOI: 10.1073/Pnas.0504952102  1
2005 Pao W, Miller VA, Politi KA, Riely GJ, Somwar R, Zakowski MF, Kris MG, Varmus H. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain Plos Medicine. 2: 0225-0235. PMID 15737014 DOI: 10.1371/Journal.Pmed.0020073  1
2005 Pao W, Wang TY, Riely GJ, Miller VA, Pan Q, Ladanyi M, Zakowski MF, Heelan RT, Kris MG, Varmus HE. KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. Plos Medicine. 2: e17. PMID 15696205 DOI: 10.1371/Journal.Pmed.0020017  1
2005 Lewis BC, Klimstra DS, Socci ND, Xu S, Koutcher JA, Varmus HE. The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma. Molecular and Cellular Biology. 25: 1228-37. PMID 15684377 DOI: 10.1128/Mcb.25.4.1228-1237.2005  1
2005 Chamorro MN, Schwartz DR, Vonica A, Brivanlou AH, Cho KR, Varmus HE. FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development. The Embo Journal. 24: 73-84. PMID 15592430 DOI: 10.1038/Sj.Emboj.7600460  1
2004 Cong F, Schweizer L, Varmus H. Wnt signals across the plasma membrane to activate the β-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP Development. 131: 5103-5115. PMID 15459103 DOI: 10.1242/Dev.01318  1
2004 Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, ... ... Varmus H, et al. The knockout mouse project. Nature Genetics. 36: 921-4. PMID 15340423 DOI: 10.1038/Ng0904-921  1
2004 Pao W, Miller V, Zakowski M, Doherty J, Politi K, Sarkaria I, Singh B, Heelan R, Rusch V, Fulton L, Mardis E, Kupfer D, Wilson R, Kris M, Varmus H. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proceedings of the National Academy of Sciences of the United States of America. 101: 13306-11. PMID 15329413 DOI: 10.1073/Pnas.0405220101  1
2004 Podsypanina K, Li Y, Varmus HE. Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype. Bmc Medicine. 2: 24. PMID 15198801 DOI: 10.1186/1741-7015-2-24  1
2004 Zinkernagel RM. The challenges of an HIV vaccine enterprise. Science (New York, N.Y.). 303: 1294-7; author reply. PMID 14988536 DOI: 10.1126/science.303.5662.1294  1
2004 Cong F, Varmus H. Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of β-catenin Proceedings of the National Academy of Sciences of the United States of America. 101: 2882-2887. PMID 14981260 DOI: 10.1073/Pnas.0307344101  1
2004 Cong F, Schweizer L, Varmus H. Casein Kinase Iε Modulates the Signaling Specificities of Dishevelled Molecular and Cellular Biology. 24: 2000-2011. PMID 14966280 DOI: 10.1128/Mcb.24.5.2000-2011.2004  1
2004 Eisen MB, Brown PO, Varmus HE. PLoS Medicine - A medical journal for the internet age Plos Medicine. 1: 002-003. DOI: 10.1371/Journal.Pmed.0010031  1
2003 Lewis BC, Klimstra DS, Varmus HE. The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer. Genes & Development. 17: 3127-38. PMID 14681205 DOI: 10.1101/Gad.1140403  1
2003 Li Y, Welm B, Podsypanina K, Huang S, Chamorro M, Zhang X, Rowlands T, Egeblad M, Cowin P, Werb Z, Tan LK, Rosen JM, Varmus HE. Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 15853-8. PMID 14668450 DOI: 10.1073/Pnas.2136825100  1
2003 Cong F, Schweizer L, Chamorro M, Varmus H. Requirement for a Nuclear Function of β-Catenin in Wnt Signaling Molecular and Cellular Biology. 23: 8462-8470. PMID 14612392 DOI: 10.1128/Mcb.23.23.8462-8470.2003  1
2003 Varmus H. Genomic empowerment: the importance of public databases Nature Genetics. 35: 3. PMID 14578889 DOI: 10.1038/Ng1186  1
2003 Varmus H, Klausner R, Zerhouni E, Acharya T, Daar AS, Singer PA. Public health. Grand Challenges in Global Health. Science (New York, N.Y.). 302: 398-9. PMID 14563993 DOI: 10.1126/Science.1091769  1
2003 Brown PO, Eisen MB, Varmus HE. Why PLoS became a publisher. Plos Biology. 1: E36. PMID 14551926 DOI: 10.1371/Journal.Pbio.0000036  1
2003 Cong F, Zhang J, Pao W, Zhou P, Varmus H. A protein knockdown strategy to study the function of β-catenin in tumorigenesis Bmc Molecular Biology. 4. PMID 14516475 DOI: 10.1186/1471-2199-4-10  1
2003 Pao W, Klimstra DS, Fisher GH, Varmus HE. Use of avian retroviral vectors to introduce transcriptional regulators into mammalian cells for analyses of tumor maintenance. Proceedings of the National Academy of Sciences of the United States of America. 100: 8764-9. PMID 12857957 DOI: 10.1073/Pnas.1133333100  1
2003 Klausner RD, Fauci AS, Corey L, Nabel GJ, Gayle H, Berkley S, Haynes BF, Baltimore D, Collins C, Douglas RG, Esparza J, Francis DP, Ganguly NK, Gerberding JL, Johnston MI, ... ... Varmus H, et al. Medicine. The need for a global HIV vaccine enterprise. Science (New York, N.Y.). 300: 2036-9. PMID 12829768 DOI: 10.1126/Science.1086916  1
2003 Schweizer L, Varmus H. Wnt/Wingless signaling through β-catenin requires the function of both LRP/Arrow and frizzled classes of receptors Bmc Cell Biology. 4. PMID 12729465 DOI: 10.1186/1471-2121-4-4  1
2003 Atlas R, Campbell P, Cozzarelli NR, Curfman G, Enquist L, Fink G, Flanagin A, Fletcher J, George E, Hammes G, Heyman D, Inglesby T, Kaplan S, Kennedy D, Krug J, ... ... Varmus H, et al. Statement on scientific publication and security. Science (New York, N.Y.). 299: 1149. PMID 12595658 DOI: 10.1126/Science.299.5610.1149  1
2002 Varmus H. Building a global culture of science Lancet. 360: s1-s4. PMID 12504480 DOI: 10.1016/S0140-6736(02)11796-X  1
2002 Varmus H. Getting ready for gene-based medicine New England Journal of Medicine. 347: 1526-1527. PMID 12421898 DOI: 10.1056/Nejme020119  1
2002 Eisen MB, Brown PO, Varmus HE. Public-access group supports PubMed Central. Nature. 419: 111. PMID 12226637 DOI: 10.1038/419111C  1
2002 Orsulic S, Li Y, Soslow RA, Vitale-Cross LA, Gutkind JS, Varmus HE. Induction of ovarian cancer by defined multiple genetic changes in a mouse model system. Cancer Cell. 1: 53-62. PMID 12086888 DOI: 10.1016/S1535-6108(01)00002-2  1
2002 Varmus H. The weaknesses of science for profit Oncologist. 7: 4-5. PMID 11854541 DOI: 10.1634/Theoncologist.7-1-4  1
2001 Fisher GH, Wellen SL, Klimstra D, Lenczowski JM, Tichelaar JW, Lizak MJ, Whitsett JA, Koretsky A, Varmus HE. Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. Genes & Development. 15: 3249-62. PMID 11751631 DOI: 10.1101/Gad.947701  1
2001 Varmus H. How popular TV shows shape public perceptions of medical scientists Mount Sinai Journal of Medicine. 68: 346-349. PMID 11687861  1
2001 Lewis BC, Chinnasamy N, Morgan RA, Varmus HE. Development of an avian leukosis-sarcoma virus subgroup A pseudotyped lentiviral vector. Journal of Virology. 75: 9339-44. PMID 11533197 DOI: 10.1128/Jvi.75.19.9339-9344.2001  1
2001 Varmus H, Schaal B. Forum for agricultural biotechnology debates [4] Science. 292: 2252. PMID 11424946 DOI: 10.1126/Science.292.5525.2252A  1
2001 Burr R, Randerath K, Goldhaber P, Varmus H. The growing family of NIH institutes [1] Science. 292: 1835-1836. PMID 11398826  1
2001 Varmus H. A mover in the biomedical community. An interview with Harold Varmus, President of Memorial Sloan-Kettering Cancer Center in New York City and former Director of HIH Embo Reports. 2: 360-362. PMID 11375922  1
2001 Chamorro M, Czar MJ, Debnath J, Cheng G, Lenardo MJ, Varmus HE, Schwartzberg PL. Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk. Bmc Immunology. 2: 3. PMID 11353545 DOI: 10.1186/1471-2172-2-3  1
2001 Roberts RJ, Varmus HE, Ashburner M, Brown PO, Eisen MB, Khosla C, Kirschner M, Nusse R, Scott M, Wold B. Information access. Building a "GenBank" of the published literature. Science (New York, N.Y.). 291: 2318-9. PMID 11269300 DOI: 10.1126/Science.1060273  1
2001 Varmus H. Proliferation of National Institutes of Health Science. 291: 1903-1905. PMID 11245194 DOI: 10.1126/Science.1059063  1
2001 Li Y, Podsypanina K, Liu X, Crane A, Tan LK, Parsons R, Varmus HE. Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice. Bmc Molecular Biology. 2: 2. PMID 11178110 DOI: 10.1186/1471-2199-2-2  0.96
2001 Xing L, Venegas AM, Chen A, Garrett-Beal L, Boyce BF, Varmus HE, Schwartzberg PL. Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival. Genes & Development. 15: 241-53. PMID 11157779 DOI: 10.1101/Gad.840301  1
2001 Varmus H. Harold Varmus [interview by Karen Birmingham] Nature Medicine. 7: 10. PMID 11135598 DOI: 10.1038/83228  1
2001 Li Y, Podsypanina K, Liu X, Crane A, Tan LK, Parsons R, Varmus HE. Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice Bmc Molecular Biology. 2. DOI: 10.1186/1471-2199-2-2  1
2000 Varmus HE. The challenge of making laws on the shifting terrain of science. The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics. 28: 46-53. PMID 11244844  1
2000 Williams BO, Barish GD, Klymkowsky MW, Varmus HE. A comparative evaluation of beta-catenin and plakoglobin signaling activity. Oncogene. 19: 5720-8. PMID 11126358 DOI: 10.1038/Sj.Onc.1203921  1
2000 Nathan DG, Varmus HE. The National Institutes of Health and clinical research: a progress report. Nature Medicine. 6: 1201-4. PMID 11062519 DOI: 10.1038/81282  1
2000 Li Y, Hively WP, Varmus HE. Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer. Oncogene. 19: 1002-9. PMID 10713683 DOI: 10.1038/Sj.Onc.1203273  1
2000 Varmus H. Ushering in a new age of scientific publishing Bmc News and Views. 1.  1
1999 Zorn AM, Barish GD, Williams BO, Lavender P, Klymkowsky MW, Varmus HE. Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin. Molecular Cell. 4: 487-98. PMID 10549281 DOI: 10.1016/S1097-2765(00)80200-2  1
1999 Klymkowsky MW, Williams BO, Barish GD, Varmus HE, Vourgourakis YE. Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling. Molecular Biology of the Cell. 10: 3151-69. PMID 10512857 DOI: 10.1091/Mbc.10.10.3151  1
1999 Fisher GH, Orsulic S, Holland E, Hively WP, Li Y, Lewis BC, Williams BO, Varmus HE. Development of a flexible and specific gene delivery system for production of murine tumor models. Oncogene. 18: 5253-60. PMID 10498877 DOI: 10.1038/Sj.Onc.1203087  1
1999 Schaeffer EM, Debnath J, Yap G, McVicar D, Liao XC, Littman DR, Sher A, Varmus HE, Lenardo MJ, Schwartzberg PL. Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science (New York, N.Y.). 284: 638-41. PMID 10213685 DOI: 10.1126/Science.284.5414.638  1
1999 Bocchinfuso WP, Hively WP, Couse JF, Varmus HE, Korach KS. A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha. Cancer Research. 59: 1869-76. PMID 10213494  1
1999 Debnath J, Chamorro M, Czar MJ, Schaeffer EM, Lenardo MJ, Varmus HE, Schwartzberg PL. rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases. Molecular and Cellular Biology. 19: 1498-507. PMID 9891083 DOI: 10.1128/Mcb.19.2.1498  1
1998 Holland EC, Hively WP, DePinho RA, Varmus HE. A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes & Development. 12: 3675-85. PMID 9851974 DOI: 10.1101/Gad.12.23.3675  1
1998 Holland EC, Hively WP, Gallo V, Varmus HE. Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes. Genes & Development. 12: 3644-9. PMID 9851971 DOI: 10.1101/Gad.12.23.3644  1
1998 Varmus HE. National Institutes of Health in the tropics. The American Journal of Tropical Medicine and Hygiene. 59: 24-8. PMID 9684621 DOI: 10.4269/Ajtmh.1998.59.24  1
1998 Varmus H, Nathanson N. Science and the control of AIDS. Science (New York, N.Y.). 280: 1815. PMID 9669926 DOI: 10.1126/Science.280.5371.1815A  1
1998 Bates P, Rong L, Varmus HE, Young JA, Crittenden LB. Genetic mapping of the cloned subgroup A avian sarcoma and leukosis virus receptor gene to the TVA locus. Journal of Virology. 72: 2505-8. PMID 9499114 DOI: 10.1128/Jvi.72.3.2505-2508.1998  1
1998 Holland EC, Varmus HE. Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 1218-23. PMID 9448312 DOI: 10.1073/Pnas.95.3.1218  1
1997 Saint-Jeannet JP, He X, Varmus HE, Dawid IB. Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3a. Proceedings of the National Academy of Sciences of the United States of America. 94: 13713-8. PMID 9391091 DOI: 10.1073/Pnas.94.25.13713  1
1997 Schwartzberg PL, Xing L, Hoffmann O, Lowell CA, Garrett L, Boyce BF, Varmus HE. Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice. Genes & Development. 11: 2835-44. PMID 9353253 DOI: 10.1101/Gad.11.21.2835  1
1997 Jones JM, Attardi L, Godley LA, Laucirica R, Medina D, Jacks T, Varmus HE, Donehower LA. Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 8: 829-38. PMID 9269892  1
1997 Willert K, Brink M, Wodarz A, Varmus H, Nusse R. Casein kinase 2 associates with and phosphorylates dishevelled Embo Journal. 16: 3089-3096. PMID 9214626 DOI: 10.1093/Emboj/16.11.3089  1
1997 Finch PW, He X, Kelley MJ, Uren A, Schaudies RP, Popescu NC, Rudikoff S, Aaronson SA, Varmus HE, Rubin JS. Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Proceedings of the National Academy of Sciences of the United States of America. 94: 6770-5. PMID 9192640 DOI: 10.1073/pnas.94.13.6770  1
1997 He X, Saint-Jeannet JP, Wang Y, Nathans J, Dawid I, Varmus H. A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science (New York, N.Y.). 275: 1652-4. PMID 9054360 DOI: 10.1126/Science.275.5306.1652  1
1996 Donehower LA, Godley LA, Aldaz CM, Pyle R, Shi YP, Pinkel D, Gray J, Bradley A, Medina D, Varmus HE. The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model. Progress in Clinical and Biological Research. 395: 1-11. PMID 8895979  1
1996 Godley LA, Kopp JB, Eckhaus M, Paglino JJ, Owens J, Varmus HE. Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys. Genes & Development. 10: 836-50. PMID 8846920 DOI: 10.1101/Gad.10.7.836  1
1996 Chen X, Kang H, Shen LX, Chamorro M, Varmus HE, Tinoco I. A characteristic bent conformation of RNA pseudoknots promotes -1 frameshifting during translation of retroviral RNA. Journal of Molecular Biology. 260: 479-83. PMID 8759314 DOI: 10.1006/Jmbi.1996.0415  1
1996 Broccoli D, Godley LA, Donehower LA, Varmus HE, de Lange T. Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation. Molecular and Cellular Biology. 16: 3765-72. PMID 8668193 DOI: 10.1128/Mcb.16.7.3765  1
1996 Lowell CA, Niwa M, Soriano P, Varmus HE. Deficiency of the Hck and Src tyrosine kinases results in extreme levels of extramedullary hematopoiesis. Blood. 87: 1780-92. PMID 8634424 DOI: 10.1182/Blood.V87.5.1780.Bloodjournal8751780  1
1996 Leavitt AD, Robles G, Alesandro N, Varmus HE. Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection. Journal of Virology. 70: 721-8. PMID 8551608 DOI: 10.1128/Jvi.70.2.721-728.1996  1
1996 Shinar RZ, Sikorski RS, Varmus HE. In Vivo gene targeting to the mouse mammary gland using cationic lipids Journal of Investigative Medicine. 44: 166A.  1
1995 Taylor IC, Roy S, Varmus HE. Overexpression of the Sky receptor tyrosine kinase at the cell surface or in the cytoplasm results in ligand-independent activation. Oncogene. 11: 2619-26. PMID 8545119  1
1995 Taylor IC, Roy S, Yaswen P, Stampfer MR, Varmus HE. Mouse mammary tumors express elevated levels of RNA encoding the murine homology of SKY, a putative receptor tyrosine kinase. The Journal of Biological Chemistry. 270: 6872-80. PMID 7896835 DOI: 10.1074/Jbc.270.12.6872  1
1995 Chen X, Chamorro M, Lee SI, Shen LX, Hines JV, Tinoco I, Varmus HE. Structural and functional studies of retroviral RNA pseudoknots involved in ribosomal frameshifting: nucleotides at the junction of the two stems are important for efficient ribosomal frameshifting. The Embo Journal. 14: 842-52. PMID 7882986  1
1995 Varmus HE. An overview of the FY-1996 budget for the National Institutes of Health. Academic Medicine : Journal of the Association of American Medical Colleges. 70: 385-7. PMID 7748383 DOI: 10.1097/00001888-199505000-00014  1
1995 He X, Saint-Jeannet JP, Woodgett JR, Varmus HE, Dawid IB. Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature. 374: 617-22. PMID 7715701 DOI: 10.1038/374617A0  1
1995 Donehower LA, Godley LA, Aldaz CM, Pyle R, Shi YP, Pinkel D, Gray J, Bradley A, Medina D, Varmus HE. Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability. Genes & Development. 9: 882-95. PMID 7705663 DOI: 10.1101/Gad.9.7.882  1
1995 Ranade K, Hussussian CJ, Sikorski RS, Varmus HE, Goldstein AM, Tucker MA, Serrano M, Hannon GJ, Beach D, Dracopoli NC. Mutations associated with familial melanoma impair p16INK4 function. Nature Genetics. 10: 114-6. PMID 7647780 DOI: 10.1038/Ng0595-114  1
1995 Varmus HE. Harold E. Varmus, MD. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 43: 220-6. PMID 7614067  1
1995 Lee SI, Umen JG, Varmus HE. A genetic screen identifies cellular factors involved in retroviral -1 frameshifting. Proceedings of the National Academy of Sciences of the United States of America. 92: 6587-91. PMID 7604038 DOI: 10.1073/Pnas.92.14.6587  1
1995 Kaplan KB, Swedlow JR, Morgan DO, Varmus HE. c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism. Genes & Development. 9: 1505-17. PMID 7541382 DOI: 10.1101/Gad.9.12.1505  1
1995 Boeuf H, Murphy J, Bibbins KB, Varmus HE. Binding in vitro of phosphotyrosine-containing proteins to pp60c-src SH2 domain does not correlate with CEF transformation. Oncogene. 10: 433-8. PMID 7531318  1
1995 Chen X, Chamorro M, Lee SI, Shen LX, Hines JV, Tinoco I, Varmus HE. Structural and functional studies of retroviral RNA pseudoknots involved in ribosomal frameshifting: nucleotides at the junction of the two stems are important for efficient ribosomal frameshifting. The Embo Journal. 14: 842-852. DOI: 10.1002/J.1460-2075.1995.Tb07062.X  0.44
1994 Verderame MF, Varmus HE. Highly conserved amino acids in the SH2 and catalytic domains of v-src are altered in naturally occurring, transformation-defective alleles. Oncogene. 9: 175-82. PMID 8302576  1
1994 Varmus HE, Lowell CA. Cancer genes and hematopoiesis. Blood. 83: 5-9. PMID 8274752 DOI: 10.1182/Blood.V83.1.5.5  1
1994 Lowell CA, Soriano P, Varmus HE. Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity. Genes & Development. 8: 387-98. PMID 8125254 DOI: 10.1101/Gad.8.4.387  1
1994 Gilbert JM, Bates P, Varmus HE, White JM. The receptor for the subgroup A avian leukosis-sarcoma viruses binds to subgroup A but not to subgroup C envelope glycoprotein. Journal of Virology. 68: 5623-8. PMID 8057442 DOI: 10.1128/Jvi.68.9.5623-5628.1994  1
1994 Federspiel MJ, Bates P, Young JA, Varmus HE, Hughes SH. A system for tissue-specific gene targeting: transgenic mice susceptible to subgroup A avian leukosis virus-based retroviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 91: 11241-5. PMID 7972042 DOI: 10.1073/Pnas.91.23.11241  1
1994 Müller HP, Varmus HE. DNA bending creates favored sites for retroviral integration: an explanation for preferred insertion sites in nucleosomes. The Embo Journal. 13: 4704-14. PMID 7925312 DOI: 10.1002/J.1460-2075.1994.Tb06794.X  1
1994 Varmus HE, Godley LA, Roy S, Taylor IC, Yuschenkoff L, Shi YP, Pinkel D, Gray J, Pyle R, Aldaz CM. Defining the steps in a multistep mouse model for mammary carcinogenesis. Cold Spring Harbor Symposia On Quantitative Biology. 59: 491-9. PMID 7587104 DOI: 10.1101/Sqb.1994.059.01.054  1
1994 Kaplan KB, Bibbins KB, Swedlow JR, Arnaud M, Morgan DO, Varmus HE. Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527. The Embo Journal. 13: 4745-56. PMID 7525268 DOI: 10.1002/J.1460-2075.1994.Tb06800.X  1
1993 Shackleford GM, Shivakumar S, Shiue L, Mason J, Kenyon C, Varmus HE. Two wnt genes in Caenorhabditis elegans. Oncogene. 8: 1857-64. PMID 8510930  1
1993 Bishop JM, Kirschner M, Varmus H. Science and the new administration Science. 259: 444-445. PMID 8424162 DOI: 10.1126/Science.8424162  1
1993 Leavitt AD, Shiue L, Varmus HE. Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro. The Journal of Biological Chemistry. 268: 2113-9. PMID 8420982  1
1993 Bates P, Young JA, Varmus HE. A receptor for subgroup A Rous sarcoma virus is related to the low density lipoprotein receptor. Cell. 74: 1043-51. PMID 8402880 DOI: 10.1016/0092-8674(93)90726-7  1
1993 Young JA, Bates P, Varmus HE. Isolation of a chicken gene that confers susceptibility to infection by subgroup A avian leukosis and sarcoma viruses. Journal of Virology. 67: 1811-6. PMID 8383211 DOI: 10.1128/Jvi.67.4.1811-1816.1993  1
1993 Shackleford GM, MacArthur CA, Kwan HC, Varmus HE. Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4. Proceedings of the National Academy of Sciences of the United States of America. 90: 740-4. PMID 8380647  1
1993 Shackleford GM, Willert K, Wang J, Varmus HE. The Wnt-1 proto-oncogene induces changes in morphology, gene expression, and growth factor responsiveness in PC12 cells. Neuron. 11: 865-75. PMID 8240810 DOI: 10.1016/0896-6273(93)90116-9  1
1993 Parkin NT, Kitajewski J, Varmus HE. Activity of Wnt-1 as a transmembrane protein. Genes & Development. 7: 2181-93. PMID 8224845 DOI: 10.1101/Gad.7.11.2181  1
1993 Müller HP, Pryciak PM, Varmus HE. Retroviral integration machinery as a probe for DNA structure and associated proteins. Cold Spring Harbor Symposia On Quantitative Biology. 58: 533-41. PMID 7956067 DOI: 10.1101/Sqb.1993.058.01.060  1
1993 Bibbins KB, Boeuf H, Varmus HE. Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides. Molecular and Cellular Biology. 13: 7278-87. PMID 7504171 DOI: 10.1128/Mcb.13.12.7278  1
1992 Nusse R, Varmus HE. Wnt genes. Cell. 69: 1073-87. PMID 1617723 DOI: 10.1016/0092-8674(92)90630-U  1
1992 Leavitt AD, Rose RB, Varmus HE. Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae. Journal of Virology. 66: 2359-68. PMID 1548767 DOI: 10.1128/Jvi.66.4.2359-2368.1992  1
1992 Mason JO, Kitajewski J, Varmus HE. Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line. Molecular Biology of the Cell. 3: 521-33. PMID 1535241 DOI: 10.1091/Mbc.3.5.521  1
1992 Kitajewski J, Mason JO, Varmus HE. Interaction of Wnt-1 proteins with the binding protein BiP. Molecular and Cellular Biology. 12: 784-90. PMID 1531088 DOI: 10.1128/Mcb.12.2.784  1
1992 Jue SF, Bradley RS, Rudnicki JA, Varmus HE, Brown AM. The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells. Molecular and Cellular Biology. 12: 321-8. PMID 1530877 DOI: 10.1128/Mcb.12.1.321  1
1992 Kwan H, Pecenka V, Tsukamoto A, Parslow TG, Guzman R, Lin TP, Muller WJ, Lee FS, Leder P, Varmus HE. Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice. Molecular and Cellular Biology. 12: 147-54. PMID 1530875 DOI: 10.1128/Mcb.12.1.147  1
1992 Kaplan KB, Swedlow JR, Varmus HE, Morgan DO. Association of p60c-src with endosomal membranes in mammalian fibroblasts. The Journal of Cell Biology. 118: 321-33. PMID 1378446 DOI: 10.1083/Jcb.118.2.321  1
1992 Pryciak PM, Müller HP, Varmus HE. Simian virus 40 minichromosomes as targets for retroviral integration in vivo. Proceedings of the National Academy of Sciences of the United States of America. 89: 9237-41. PMID 1329090 DOI: 10.1073/Pnas.89.19.9237  1
1992 Pryciak PM, Varmus HE. Fv-1 restriction and its effects on murine leukemia virus integration in vivo and in vitro. Journal of Virology. 66: 5959-66. PMID 1326652 DOI: 10.1128/Jvi.66.10.5959-5966.1992  1
1992 Parkin NT, Chamorro M, Varmus HE. Human immunodeficiency virus type 1 gag-pol frameshifting is dependent on downstream mRNA secondary structure: demonstration by expression in vivo. Journal of Virology. 66: 5147-51. PMID 1321294 DOI: 10.1128/Jvi.66.8.5147-5151.1992  1
1992 Pryciak PM, Varmus HE. Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection. Cell. 69: 769-80. PMID 1317268 DOI: 10.1016/0092-8674(92)90289-O  1
1992 Pryciak PM, Sil A, Varmus HE. Retroviral integration into minichromosomes in vitro. The Embo Journal. 11: 291-303. PMID 1310932 DOI: 10.1002/J.1460-2075.1992.Tb05052.X  1
1992 Chamorro M, Parkin N, Varmus HE. An RNA pseudoknot and an optimal heptameric shift site are required for highly efficient ribosomal frameshifting on a retroviral messenger RNA. Proceedings of the National Academy of Sciences of the United States of America. 89: 713-7. PMID 1309954 DOI: 10.1073/Pnas.89.2.713  1
1992 Bourne HR, Varmus HE. Oncogenes and cell proliferation Current Opinion in Genetics and Development. 2: 1-3. DOI: 10.1016/S0959-437X(05)80313-2  1
1991 Seeger C, Baldwin B, Hornbuckle WE, Yeager AE, Tennant BC, Cote P, Ferrell L, Ganem D, Varmus HE. Woodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host. Journal of Virology. 65: 1673-9. PMID 2002538 DOI: 10.1128/Jvi.65.4.1673-1679.1991  1
1991 Basu S, Varmus HE. Retraction. Moloney murine leukemia virus integration protein produced in yeast binds specifically to viral att sites. Journal of Virology. 65: 7086. PMID 1942261  1
1991 Nusse R, Brown A, Papkoff J, Scambler P, Shackleford G, McMahon A, Moon R, Varmus H. A new nomenclature for int-1 and related genes: The Wnt gene family Cell. 64: 231. PMID 1846319 DOI: 10.1016/0092-8674(91)90633-A  1
1991 Morgan DO, Kaplan JM, Bishop JM, Varmus HE. Production of p60c-src by baculovirus expression and immunoaffinity purification. Methods in Enzymology. 200: 645-60. PMID 1720191 DOI: 10.1016/0076-6879(91)00177-X  1
1990 de Lange T, Shiue L, Myers RM, Cox DR, Naylor SL, Killery AM, Varmus HE. Structure and variability of human chromosome ends. Molecular and Cellular Biology. 10: 518-27. PMID 2300052 DOI: 10.1128/Mcb.10.2.518  1
1990 Basu S, Varmus HE. Moloney murine leukemia virus integration protein produced in yeast binds specifically to viral att sites. Journal of Virology. 64: 5617-25. PMID 2214028 DOI: 10.1128/Jvi.64.11.5617-5625.1990  1
1990 Young JA, Bates P, Willert K, Varmus HE. Efficient incorporation of human CD4 protein into avian leukosis virus particles. Science (New York, N.Y.). 250: 1421-3. PMID 2175047 DOI: 10.1126/Science.2175047  1
1990 Hirai H, Varmus HE. Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src. Molecular and Cellular Biology. 10: 1307-18. PMID 2108315 DOI: 10.1128/Mcb.10.4.1307  1
1990 Varmus HE. Nobel lecture. Retroviruses and oncogenes. I. Bioscience Reports. 10: 413-30. PMID 1704261 DOI: 10.1007/Bf01152288  1
1990 Hirai H, Varmus HE. SH2 mutants of c-src that are host dependent for transformation are trans-dominant inhibitors of mouse cell transformation by activated c-src. Genes & Development. 4: 2342-52. PMID 1703982 DOI: 10.1101/Gad.4.12B.2342  1
1990 Hirai H, Varmus HE. Mutations in src homology regions 2 and 3 of activated chicken c-src that result in preferential transformation of mouse or chicken cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 8592-6. PMID 1700434 DOI: 10.1073/Pnas.87.21.8592  1
1990 Chang LJ, Hirsch RC, Ganem D, Varmus HE. Effects of insertional and point mutations on the functions of the duck hepatitis B virus polymerase. Journal of Virology. 64: 5553-8. PMID 1698997 DOI: 10.1128/Jvi.64.11.5553-5558.1990  1
1990 Chang LJ, Ganem D, Varmus HE. Mechanism of translation of the hepadnaviral polymerase (P) gene. Proceedings of the National Academy of Sciences of the United States of America. 87: 5158-62. PMID 1695011 DOI: 10.1073/Pnas.87.13.5158  1
1990 Hirsch RC, Lavine JE, Chang LJ, Varmus HE, Ganem D. Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as wel as for reverse transcription. Nature. 344: 552-5. PMID 1690862 DOI: 10.1038/344552A0  1
1990 Kaplan JM, Varmus HE, Bishop JM. The src protein contains multiple domains for specific attachment to membranes. Molecular and Cellular Biology. 10: 1000-9. PMID 1689455 DOI: 10.1128/Mcb.10.3.1000  1
1989 Chang LJ, Dienstag J, Ganem D, Varmus H. Detection of antibodies against hepatitis B virus polymerase antigen in hepatitis B virus-infected patients. Hepatology (Baltimore, Md.). 10: 332-5. PMID 2759550 DOI: 10.1002/Hep.1840100314  1
1989 Bowerman B, Brown PO, Bishop JM, Varmus HE. A nucleoprotein complex mediates the integration of retroviral DNA. Genes & Development. 3: 469-78. PMID 2721960 DOI: 10.1101/Gad.3.4.469  1
1989 Brown PO, Bowerman B, Varmus HE, Bishop JM. Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein. Proceedings of the National Academy of Sciences of the United States of America. 86: 2525-9. PMID 2539592 DOI: 10.1073/Pnas.86.8.2525  1
1989 Morgan DO, Kaplan JM, Bishop JM, Varmus HE. Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase. Cell. 57: 775-86. PMID 2470513 DOI: 10.1016/0092-8674(89)90792-7  1
1989 Varmus HE. Reverse transcription in bacteria Cell. 56: 721-724. PMID 2466572 DOI: 10.1016/0092-8674(89)90673-9  1
1989 Chang LJ, Pryciak P, Ganem D, Varmus HE. Biosynthesis of the reverse transcriptase of hepatitis B viruses involves de novo translational initiation not ribosomal frameshifting. Nature. 337: 364-8. PMID 2463489 DOI: 10.1038/337364A0  1
1989 Verderame MF, Kaplan JM, Varmus HE. A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent manner. Journal of Virology. 63: 338-48. PMID 2462061 DOI: 10.1128/Jvi.63.1.338-348.1989  1
1989 Varmus H. 1 An Historical Overview of Oncogenes Cold Spring Harbor Monograph Archive. 18: 3-44. DOI: 10.1101/087969336.18.3  0.6
1989 Bishop JM, Varmus HE. Nobel Price of Physiology and Medicine Epitheorese Klinikes Farmakologias Kai Farmakokinetikes. 7: 182-186.  1
1988 Tsukamoto AS, Grosschedl R, Guzman RC, Parslow T, Varmus HE. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice Cell. 55: 619-625. PMID 3180222 DOI: 10.1016/0092-8674(88)90220-6  1
1988 Shackleford GM, Varmus HE. Construction of a clonable, infectious, and tumorigenic mouse mammary tumor virus provirus and a derivative genetic vector Proceedings of the National Academy of Sciences of the United States of America. 85: 9655-9659. PMID 2849114 DOI: 10.1073/Pnas.85.24.9655  1
1988 Jacks T, Madhani HD, Masiarz FR, Varmus HE. Signals for ribosomal frameshifting in the rous sarcoma virus gag-pol region Cell. 55: 447-458. PMID 2846182 DOI: 10.1016/0092-8674(88)90031-1  1
1988 Kaplan JM, Mardon G, Bishop JM, Varmus HE. The first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinant. Molecular and Cellular Biology. 8: 2435-41. PMID 2841581 DOI: 10.1128/Mcb.8.6.2435  1
1988 Jacks T, Power MD, Masiarz FR, Luciw PA, Barr PJ, Varmus HE. Characterization of ribosomal frameshifting in HIV-1 gag-pol expression Nature. 331: 280-283. PMID 2447506 DOI: 10.1038/331280A0  1
1987 Schwab M, Klempnauer KH, Alitalo K, Varmus H, Bishop M. Rearrangement at the 5' end of amplified c-myc in human COLO 320 cells is associated with abnormal transcription. Molecular and Cellular Biology. 6: 2752-5. PMID 3785211 DOI: 10.1128/Mcb.6.7.2752  0.48
1987 Sprengel R, Varmus HE, Ganem D. Homologous recombination between hepadnaviral genomes following in vivo DNA transfection: implications for studies of viral infectivity. Virology. 159: 454-6. PMID 3617505 DOI: 10.1016/0042-6822(87)90486-7  1
1987 Shackleford GM, Varmus HE. Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos Cell. 50: 89-95. PMID 3594566 DOI: 10.1016/0092-8674(87)90665-9  1
1987 Persing DH, Varmus HE, Ganem D. The preS1 protein of hepatitis B virus is acylated at its amino terminus with myristic acid Journal of Virology. 61: 1672-1677. PMID 3573147 DOI: 10.1128/Jvi.61.5.1672-1677.1987  1
1987 Quintrell N, Lebo R, Varmus H, Bishop JM, Pettenati MJ, Le Beau MM, Diaz MO, Rowley JD. Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells Molecular and Cellular Biology. 7: 2267-2275. PMID 3496523 DOI: 10.1128/Mcb.7.6.2267  1
1987 Papkoff J, Brown AM, Varmus HE. The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway Molecular and Cellular Biology. 7: 3978-3984. PMID 3323883 DOI: 10.1128/Mcb.7.11.3978  1
1987 Stone J, de Lange T, Ramsay G, Jakobovits E, Bishop JM, Varmus H, Lee W. Definition of regions in human c-myc that are involved in transformation and nuclear localization. Molecular and Cellular Biology. 7: 1697-709. PMID 3299053 DOI: 10.1128/Mcb.7.5.1697  1
1987 Chang C, Enders G, Sprengel R, Peters N, Varmus HE, Ganem D. Expression of the precore region of an avian hepatitis B virus is not required for viral replication. Journal of Virology. 61: 3322-5. PMID 3041052 DOI: 10.1128/Jvi.61.10.3322-3325.1987  1
1987 Seeger C, Marion PL, Ganem D, Varmus HE. In vitro recombinants of ground squirrel and woodchuck hepatitis viral DNAs produce infectious virus in squirrels. Journal of Virology. 61: 3241-7. PMID 3041044 DOI: 10.1128/Jvi.61.10.3241-3247.1987  0.64
1987 Ganem D, Varmus HE. The molecular biology of the hepatitis B viruses Annual Review of Biochemistry. 56: 651-693. PMID 3039907 DOI: 10.1146/Annurev.Bi.56.070187.003251  1
1987 Jacks T, Townsley K, Varmus HE, Majors J. Two efficient ribosomal frameshifting events are required for synthesis of mouse mammary tumor virus gag-related polyproteins Proceedings of the National Academy of Sciences of the United States of America. 84: 4298-4302. PMID 3035577 DOI: 10.1073/Pnas.84.12.4298  1
1987 Nottenburg C, Stubblefield E, Varmus HE. An aberrant avian leukosis virus provirus inserted downstream from the chicken c-myc coding sequence in a bursal lymphoma results from intrachromosomal recombination between two proviruses and deletion of cellular DNA Journal of Virology. 61: 1828-1833. PMID 3033315 DOI: 10.1128/Jvi.61.6.1828-1833.1987  1
1987 Brown PO, Bowerman B, Varmus HE, Bishop JM. Correct integration of retroviral DNA in vitro. Cell. 49: 347-56. PMID 3032450 DOI: 10.1016/0092-8674(87)90287-X  1
1987 Brown AM, Papkoff J, Fung YK, Shackleford GM, Varmus HE. Identification of protein products encoded by the proto-oncogene int-1 Molecular and Cellular Biology. 7: 3971-3977. PMID 2828922 DOI: 10.1128/Mcb.7.11.3971  1
1987 Varmus HE. Oncogenes and transcriptional control Science. 238: 1337-1339. PMID 2825348 DOI: 10.1126/Science.2825348  1
1987 Hagino-Yamagishi K, Donehower LA, Varmus HE. Retroviral DNA integrated during infection by an integration-deficient mutant of murine leukemia virus is oligomeric Journal of Virology. 61: 1964-1971. PMID 2437326 DOI: 10.1128/Jvi.61.6.1964-1971.1987  1
1987 Enders GH, Ganem D, Varmus HE. 5'-Terminal sequences influence the segregation of ground squirrel hepatitis virus RNAs into polyribosomes and viral core particles Journal of Virology. 61: 35-41. PMID 2431165 DOI: 10.1128/Jvi.61.1.35-41.1987  1
1986 Seeger C, Ganem D, Varmus HE. Biochemical and genetic evidence for the hepatitis B virus replication strategy. Science (New York, N.Y.). 232: 477-84. PMID 3961490 DOI: 10.1126/Science.3961490  1
1986 Persing DH, Varmus HE, Ganem D. Inhibition of secretion of hepatitis B surface antigen by a related presurface polypeptide Science. 234: 1388-1391. PMID 3787251 DOI: 10.1126/Science.3787251  1
1986 Brown AMC, Wildin RS, Prendergast TJ, Varmus HE. A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line Cell. 46: 1001-1009. PMID 3019559 DOI: 10.1016/0092-8674(86)90699-9  1
1986 Westaway D, Papkoff J, Moscovici C, Varmus HE. Identification of a provirally activated c-Ha-ras oncogene in an avian nephroblastoma via a novel procedure: cDNA cloning of a chimaeric viral-host transcript The Embo Journal. 5: 301-309. PMID 3011401 DOI: 10.1002/J.1460-2075.1986.Tb04213.X  1
1986 Coffin J, Haase A, Levy JA, Montagnier L, Oroszlan S, Teich N, Temin H, Toyoshima K, Varmus H, Vogt P. What to call the AIDS virus? Nature. 321: 10. PMID 3010128 DOI: 10.1038/321010a0  1
1986 Coffin J, Haase A, Levy JA, Montagnier L, Oroszlan S, Teich N, Temin H, Toyoshima K, Varmus H, Vogt P, Weiss R. Human immunodeficiency viruses [1] Science. 232: 697. PMID 3008335 DOI: 10.1126/Science.3008335  1
1986 Nottenburg C, Varmus HE. Features of the chicken c-myc gene that influence the structure of c-myc RNA in normal cells and bursal lymphomas Molecular and Cellular Biology. 6: 2800-2806. PMID 2431293 DOI: 10.1128/Mcb.6.8.2800  1
1986 Jakobovits A, Shackelford GM, Varmus HE, Martin GR. Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development Proceedings of the National Academy of Sciences of the United States of America. 83: 7806-7810. PMID 2429320 DOI: 10.1073/Pnas.83.20.7806  1
1986 Persing DH, Varmus HE, Ganem D. Antibodies to pre-S and X determinants arise during natural infection with ground squirrel hepatitis virus Journal of Virology. 60: 177-184. PMID 2427746 DOI: 10.1128/Jvi.60.1.177-184.1986  1
1985 Schwab M, Varmus HE, Bishop JM. Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture. Nature. 316: 160-2. PMID 4040214 DOI: 10.1038/316160A0  1
1985 Lin CC, Alitalo K, Schwab M, George D, Varmus HE, Bishop JM. Evolution of karyotypic abnormalities and C-MYC oncogene amplification in human colonic carcinoma cell lines. Chromosoma. 92: 11-5. PMID 4006596 DOI: 10.1007/Bf00327240  1
1985 Trueba D, Phelan M, Nelson J, Beck F, Pecha BS, Brown RJ, Varmus HE, Ganem D. Transmission of ground squirrel hepatitis virus to homologous and heterologous hosts Hepatology. 5: 435-439. PMID 3997073 DOI: 10.1002/Hep.1840050316  1
1985 Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM. Amplification of N-myc sequences in primary human neuroblastomas: correlation with advanced disease stage. Progress in Clinical and Biological Research. 175: 105-13. PMID 3991726  1
1985 Schwab M, Ramsay G, Alitalo K, Varmus HE, Bishop JM, Martinsson T, Levan G, Levan A. Amplification and enhanced expression of the c-myc oncogene in mouse SEWA tumour cells. Nature. 315: 345-7. PMID 3889656 DOI: 10.1038/315345A0  1
1985 Persing DH, Varmus HE, Ganem D. A frameshift mutation in the pre-S region of the human hepatitis B virus genome allows production of surface antigen particles but eliminates binding to polymerized albumin Proceedings of the National Academy of Sciences of the United States of America. 82: 3440-3444. PMID 3858831 DOI: 10.1073/Pnas.82.10.3440  1
1985 Lee WMF, Schwab M, Westaway D, Varmus HE. Augmented expression of normal c-myc is sufficient for cotransformation of rat embryo cells with a mutant ras gene Molecular and Cellular Biology. 5: 3345-3356. PMID 3837844 DOI: 10.1128/Mcb.5.12.3345  1
1985 Fung YKT, Shackleford GM, Brown AMC, Sanders GS, Varmus HE. Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene Molecular and Cellular Biology. 5: 3337-3344. PMID 3018519 DOI: 10.1128/Mcb.5.12.3337  1
1985 Varmus HE. Viruses, genes, and cancer. I. The discovery of cellular oncogenes and their role in neoplasia Cancer. 55: 2324-2328. PMID 2985231 DOI: 10.1002/1097-0142(19850515)55:10<2324::Aid-Cncr2820551004>3.0.Co;2-A  1
1985 Mossie KG, Young MW, Varmus HE. Extrachromosomal DNA forms of copia-like transposable elements, F elements and middle repetitive DNA sequences in Drosophila melanogaster. Variation in cultured cells and embryos. Journal of Molecular Biology. 182: 31-43. PMID 2582138 DOI: 10.1016/0022-2836(85)90025-7  1
1985 Varmus HE. Molecular biology: Reverse transcriptase rides again Nature. 314: 583-584. PMID 2581138 DOI: 10.1038/314583A0  1
1985 Parker RC, Mardon G, Lebo RV, Varmus HE, Bishop JM. Isolation of duplicated human c-src genes located on chromosomes 1 and 20. Molecular and Cellular Biology. 5: 831-8. PMID 2581127 DOI: 10.1128/Mcb.5.4.831  1
1985 Jacks T, Varmus HE. Expression of the Rous sarcoma virus pol gene by ribosomal frameshifting Science. 230: 1237-1242. PMID 2416054 DOI: 10.1126/Science.2416054  1
1984 Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science (New York, N.Y.). 224: 1121-4. PMID 6719137 DOI: 10.1126/Science.6719137  1
1984 Schwab M, Varmus HE, Bishop JM, Grzeschik KH, Naylor SL, Sakaguchi AY, Brodeur G, Trent J. Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc. Nature. 308: 288-91. PMID 6700732 DOI: 10.1038/308288A0  1
1984 Schwab M, Ellison J, Busch M, Rosenau W, Varmus HE, Bishop JM. Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America. 81: 4940-4. PMID 6589638 DOI: 10.1073/Pnas.81.15.4940  0.96
1984 Parker RC, Varmus HE, Bishop JM. Expression of v-src and chicken c-src in rat cells demonstrates qualitative differences between pp60v-src and pp60c-src. Cell. 37: 131-9. PMID 6426802 DOI: 10.1016/0092-8674(84)90308-8  1
1984 Varmus HE. The molecular genetics of cellular oncogenes Annual Review of Genetics. 18: 553-612. PMID 6397126 DOI: 10.1146/Annurev.Ge.18.120184.003005  1
1984 Westaway D, Payne G, Varmus HE. Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors Proceedings of the National Academy of Sciences of the United States of America. 81: 843-847. PMID 6322173 DOI: 10.1073/Pnas.81.3.843  1
1984 Nusse R, van Ooyen A, Cox D, Fung YK, Varmus H. Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature. 307: 131-6. PMID 6318122 DOI: 10.1038/307131A0  1
1984 Donehower LA, Varmus HE. A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration Proceedings of the National Academy of Sciences of the United States of America. 81: 6461-6465. PMID 6208550 DOI: 10.1073/Pnas.81.20.6461  1
1984 Standring DN, Rutter WJ, Varmus HE, Ganem D. Transcription of the hepatitis B surface antigen gene in cultured murine cells initiates within the presurface region Journal of Virology. 50: 563-571. PMID 6200609 DOI: 10.1128/Jvi.50.2.563-571.1984  1
1984 Luciw PA, Oppermann H, Bishop JM, Varmus HE. Integration and expression of several molecular forms of Rous sarcoma virus DNA used for transfection of mouse cells. Molecular and Cellular Biology. 4: 1260-9. PMID 6095056 DOI: 10.1128/Mcb.4.7.1260  1
1984 Jakobovits EB, Majors JE, Varmus HE. Hormonal regulation of the rous sarcoma virus src gene via a heterologous promoter defines a threshold dose for cellular transformation Cell. 38: 757-765. PMID 6091899 DOI: 10.1016/0092-8674(84)90271-X  1
1984 Seeger C, Ganem D, Varmus HE. The cloned genome of ground squirrel hepatitis virus is infectious in the animal. Proceedings of the National Academy of Sciences of the United States of America. 81: 5849-52. PMID 6091114 DOI: 10.1073/Pnas.81.18.5849  1
1984 Seeger C, Ganem D, Varmus HE. Nucleotide sequence of an infectious molecularly cloned genome of ground squirrel hepatitis virus. Journal of Virology. 51: 367-75. PMID 6086950 DOI: 10.1128/Jvi.51.2.367-375.1984  1
1983 Schwab M, Alitalo K, Klempnauer KH, Varmus HE, Bishop JM, Gilbert F, Brodeur G, Goldstein M, Trent J. Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature. 305: 245-8. PMID 6888561 DOI: 10.1038/305245A0  0.96
1983 Weiser B, Ganem D, Seeger C, Varmus HE. Closed circular viral DNA and asymmetrical heterogeneous forms in livers from animals infected with ground squirrel hepatitis virus. Journal of Virology. 48: 1-9. PMID 6887347 DOI: 10.1128/Jvi.48.1.1-9.1983  1
1983 Varmus HE. Using retroviruses as insertional mutagens to identify cellular oncogenes Progress in Clinical and Biological Research. 119: 23-35. PMID 6867028  1
1983 Majors JE, Varmus HE. Nucleotide sequencing of an apparent proviral copy of env mRNA defines determinants of expression of the mouse mammary tumor virus env gene Journal of Virology. 47: 495-504. PMID 6312081 DOI: 10.1128/Jvi.47.3.495-504.1983  1
1983 Majors J, Varmus HE. A small region of the mouse mammary tumor virus long terminal repeat confers glucocorticoid hormone regulation on a linked heterologous gene Proceedings of the National Academy of Sciences of the United States of America. 80: 5866-5870. PMID 6310597 DOI: 10.1073/Pnas.80.19.5866  1
1983 Luciw PA, Bishop JM, Varmus HE, Capecchi MR. Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA. Cell. 33: 705-16. PMID 6307525 DOI: 10.1016/0092-8674(83)90013-2  1
1983 Schwab M, Alitalo K, Varmus HE, Bishop JM, George D. A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells. Nature. 303: 497-501. PMID 6304530 DOI: 10.1038/303497A0  1
1983 Swanstrom R, Parker RC, Varmus HE, Bishop JM. Transduction of a cellular oncogene: the genesis of Rous sarcoma virus. Proceedings of the National Academy of Sciences of the United States of America. 80: 2519-23. PMID 6302692 DOI: 10.1073/Pnas.80.9.2519  1
1983 Alitalo K, Schwab M, Lin CC, Varmus HE, Bishop JM. Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 80: 1707-11. PMID 6300869 DOI: 10.1073/Pnas.80.6.1707  1
1983 Mardon G, Varmus HE. Frameshift and intragenic suppressor mutations in a Rous sarcoma provirus suggest src encodes two proteins. Cell. 32: 871-9. PMID 6299579 DOI: 10.1016/0092-8674(83)90072-7  1
1983 Czernilofsky AP, Levinson AD, Varmus HE, Bishop JM, Tischer E, Goodman H. Corrections to the nucleotide sequence of the src gene of Rous sarcoma virus. Nature. 301: 736-8. PMID 6298633 DOI: 10.1038/301736B0  1
1982 Ganem D, Weiser B, Barchuk A, Brown RJ, Varmus HE. Biological characterization of acute infection with ground squirrel hepatitis virus Journal of Virology. 44: 366-373. PMID 7143570 DOI: 10.1128/Jvi.44.1.366-373.1982  1
1982 Nusse R, Varmus HE. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome Cell. 31: 99-109. PMID 6297757 DOI: 10.1016/0092-8674(82)90409-3  1
1982 Ganem D, Greenbaum L, Varmus HE. Virion DNA of ground squirrel hepatitis virus: Structural analysis and molecular cloning Journal of Virology. 44: 374-383. PMID 6292498 DOI: 10.1128/Jvi.44.1.374-383.1982  1
1982 Swanstrom R, Bishop JM, Varmus HE. Structure of a replication intermediate in the synthesis of Rous sarcoma virus DNA in vivo. Journal of Virology. 42: 337-41. PMID 6283154 DOI: 10.1128/Jvi.42.1.337-341.1982  1
1982 Swanstrom R, Varmus HE, Bishop JM. Nucleotide sequence of the 5' noncoding region and part of the gag gene of Rous sarcoma virus. Journal of Virology. 41: 535-41. PMID 6281465 DOI: 10.1128/Jvi.41.2.535-541.1982  1
1982 Hackett PB, Swanstrom R, Varmus HE, Bishop JM. The leader sequence of the subgenomic mRNA's of Rous sarcoma virus is approximately 390 nucleotides. Journal of Virology. 41: 527-34. PMID 6281464 DOI: 10.1128/Jvi.41.2.527-534.1982  1
1982 Payne GS, Bishop JM, Varmus HE. Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas. Nature. 295: 209-14. PMID 6276760 DOI: 10.1038/295209A0  1
1982 Varmus HE. A growing role for reverse transcription Nature. 299: 204-205. PMID 6180324 DOI: 10.1038/299204A0  1
1982 Varmus HE. Form and function of retroviral proviruses Science. 216: 812-820. PMID 6177038 DOI: 10.1126/Science.6177038  1
1982 Bishop JM, Varmus H. 9 Functions and Origins of Retroviral Transforming Genes Cold Spring Harbor Monograph Archive. 999-1108. DOI: 10.1101/087969132.10C.999  0.96
1982 Varmus H, Swanstrom R. 5 Replication of Retroviruses Cold Spring Harbor Monograph Archive. 369-512. DOI: 10.1101/087969132.10C.369  0.6
1981 Coffin JM, Varmus HE, Bishop JM, Essex M, Hardy WD, Martin GS, Rosenberg NE, Scolnick EM, Weinberg RA, Vogt PK. Proposal for naming host cell-derived inserts in retrovirus genomes. Journal of Virology. 40: 953-7. PMID 7321107 DOI: 10.1128/Jvi.40.3.953-957.1981  1
1981 Robertson DL, Varmus HE. Dexamethasone induction of the intracellular RNAs of mouse mammary tumor virus Journal of Virology. 40: 673-682. PMID 6275112 DOI: 10.1128/Jvi.40.3.673-682.1981  1
1981 Ross NL, DeLorbe W, Varmus HE, Bishop JM, Brahic M, Haase A. Persistence and expression of Marek's disease virus DNA in tumour cells and peripheral nerves studied by in situ hybridization. The Journal of General Virology. 57: 285-96. PMID 6275026 DOI: 10.1099/0022-1317-57-2-285  1
1981 Parker RC, Varmus HE, Bishop JM. Cellular homologue (c-src) of the transforming gene of Rous sarcoma virus: isolation, mapping, and transcriptional analysis of c-src and flanking regions. Proceedings of the National Academy of Sciences of the United States of America. 78: 5842-6. PMID 6272320 DOI: 10.1073/Pnas.78.9.5842  1
1981 Hughes SH, Mutschler A, Bishop JM, Varmus HE. A Rous sarcoma virus provirus is flanked by short direct repeats of a cellular DNA sequence present in only one copy prior to integration. Proceedings of the National Academy of Sciences of the United States of America. 78: 4299-303. PMID 6270669 DOI: 10.1073/Pnas.78.7.4299  1
1981 Baker B, Robison H, Varmus HE, Bishop JM. Analysis of endogenous avian retrovirus DNA and RNA: viral and cellular determinants of retrovirus gene expression. Virology. 114: 8-22. PMID 6269293 DOI: 10.1016/0042-6822(81)90248-8  1
1981 Dudley JP, Varmus HE. Purification and translation of murine mammary tumor virus mRNA's Journal of Virology. 39: 207-218. PMID 6268810 DOI: 10.1128/Jvi.39.1.207-218.1981  1
1981 Oppermann H, Levinson AD, Levintow L, Varmus HE, Bishop JM, Kawai S. Two cellular proteins that immunoprecipitate with the transforming protein of Rous sarcoma virus. Virology. 113: 736-51. PMID 6267806 DOI: 10.1016/0042-6822(81)90202-6  1
1981 Hughes SH, Vogt PK, Bishop JM, Varmus HE. Endogenous proviruses of random-bred chickens and ring-necked pheasants: analysis with restriction endonucleases. Virology. 108: 222-9. PMID 6267774 DOI: 10.1016/0042-6822(81)90540-7  0.96
1981 Hughes SH, Vogt PK, Stubblefield E, Bishop JM, Varmus HE. Integration of avian sarcoma virus DNA in chicken cells. Virology. 108: 208-21. PMID 6267772 DOI: 10.1016/0042-6822(81)90539-0  0.96
1981 Hughes SH, Toyoshima K, Bishop JM, Varmus HE. Organization of the endogenous proviruses of chickens: implications for origin and expression. Virology. 108: 189-207. PMID 6267771 DOI: 10.1016/0042-6822(81)90538-9  0.96
1981 Shank PR, Hughes SH, Varmus HE. Restriction endonuclease mapping of the DNA of Rous-Associated virus 0 reveals extensive homology in structure and sequence with avian sarcoma virus DNA Virology. 108: 177-188. PMID 6267770 DOI: 10.1016/0042-6822(81)90537-7  1
1981 Majors JE, Swanstrom R, DeLorbe WJ, Payne GS, Hughes SH, Ortiz S, Quintrell N, Bishop JM, Varmus HE. DNA intermediates in the replication of retroviruses are structurally (and perhaps functionally) related to transposable elements. Cold Spring Harbor Symposia On Quantitative Biology. 45: 731-8. PMID 6266765 DOI: 10.1101/Sqb.1981.045.01.091  1
1981 Hackett PB, Varmus HE, Bishop JM. Repair of lesions which cause premature termination of transcription in chicken embryo cells irradiated with ultraviolet light. Virology. 112: 752-6. PMID 6266149 DOI: 10.1016/0042-6822(81)90320-2  0.96
1981 Hackett PB, Varmus HE, Bishop JM. The genesis of Rous sarcoma virus messenger RNAs. Virology. 112: 714-28. PMID 6266148 DOI: 10.1016/0042-6822(81)90316-0  0.96
1981 Swanstrom R, DeLorbe WJ, Bishop JM, Varmus HE. Nucleotide sequence of cloned unintegrated avian sarcoma virus DNA: viral DNA contains direct and inverted repeats similar to those in transposable elements. Proceedings of the National Academy of Sciences of the United States of America. 78: 124-8. PMID 6264426 DOI: 10.1073/Pnas.78.1.124  1
1981 Weiss SR, Varmus HE, Bishop JM. Cell-free translation of purified avian sarcoma virus src mRNA. Virology. 110: 476-8. PMID 6261453 DOI: 10.1016/0042-6822(81)90078-7  0.96
1981 Kung HJ, Fung YK, Majors JE, Bishop JM, Varmus HE. Synthesis of plus strands of retroviral DNA in cells infected with avian sarcoma virus and mouse mammary tumor virus. Journal of Virology. 37: 127-38. PMID 6260968 DOI: 10.1128/Jvi.37.1.127-138.1981  0.96
1981 Payne GS, Courtneidge SA, Crittenden LB, Fadly AM, Bishop JM, Varmus HE. Analysis of avian leukosis virus DNA and RNA in bursal tumours: viral gene expression is not required for maintenance of the tumor state. Cell. 23: 311-22. PMID 6258797 DOI: 10.1016/0092-8674(81)90127-6  1
1980 Quintrell N, Hughes SH, Varmus HE, Bishop JM. Structure of viral DNA and RNA in mammalian cells infected with avian sarcoma virus. Journal of Molecular Biology. 143: 363-93. PMID 6262515 DOI: 10.1016/0022-2836(80)90218-1  0.96
1980 Varmus HE, Cohen JC, Hughes SH, Majors J, Bishop JM. The origin and structure of endogenous retroviral DNA. Annals of the New York Academy of Sciences. 354: 379-83. PMID 6261653 DOI: 10.1111/J.1749-6632.1980.Tb27979.X  1
1980 DeLorbe WJ, Luciw PA, Goodman HM, Varmus HE, Bishop JM. Molecular cloning and characterization of avian sarcoma virus circular DNA molecules. Journal of Virology. 36: 50-61. PMID 6255214 DOI: 10.1128/Jvi.36.1.50-61.1980  1
1980 Cohen JC, Varmus HE. Proviruses of mouse mammary tumor virus in normal and neoplastic tissues from GR and C3Hf mouse strains Journal of Virology. 35: 298-305. PMID 6255172 DOI: 10.1128/Jvi.35.2.298-305.1980  1
1980 Czernilofsky AP, DeLorbe W, Swanstrom R, Varmus HE, Bishop JM, Tischer E, Goodman HM. The nucleotide sequence of an untranslated but conserved domain at the 3' end of the avian sarcoma virus genome. Nucleic Acids Research. 8: 2967-84. PMID 6253899 DOI: 10.1093/Nar/8.13.2967  1
1980 Czernilofsky AP, Levinson AD, Varmus HE, Bishop JM, Tischer E, Goodman HM. Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product. Nature. 287: 198-203. PMID 6253794 DOI: 10.1038/287198A0  0.96
1980 Bishop JM, Courtneidge SA, Levinson AD, Oppermann H, Quintrell N, Sheiness DK, Weiss SR, Varmus HE. Origin and function of avian retrovirus transforming genes. Cold Spring Harbor Symposia On Quantitative Biology. 44: 919-30. PMID 6253223 DOI: 10.1101/Sqb.1980.044.01.099  1
1980 Hughes SH, Vogt PK, Stubblefield E, Robinson H, Bishop JM, Varmus HE. Organization of endogenous and exogenous viral and linked nonviral sequences. Cold Spring Harbor Symposia On Quantitative Biology. 44: 1077-89. PMID 6253182 DOI: 10.1101/Sqb.1980.044.01.116  0.96
1980 Kung HJ, Shank PR, Bishop JM, Varmus HE. Identification and characterization of dimeric and trimeric circular forms of avian sarcoma virus-specific DNA. Virology. 103: 425-33. PMID 6247823 DOI: 10.1016/0042-6822(80)90201-9  1
1980 Sheiness DK, Hughes SH, Varmus HE, Stubblefield E, Bishop JM. The vertebrate homolog of the putative transforming gene of avian myelocytomatosis virus: characteristics of the DNA locus and its RNA transcript. Virology. 105: 415-24. PMID 6158786 DOI: 10.1016/0042-6822(80)90042-2  0.96
1979 Hughes SH, Stubblefield E, Payvar F, Engel JD, Dodgson JB, Spector D, Cordell B, Schimke RT, Varmus HE. Gene localization by chromosome fractionation: globin genes are on at least two chromosomes and three estrogen-inducible genes are on three chromosomes. Proceedings of the National Academy of Sciences of the United States of America. 76: 1348-52. PMID 286316 DOI: 10.1073/Pnas.76.3.1348  1
1979 Hughes SH, Robinson HL, Bishop JM, Varmus HE. The replication of subgroup E avian retroviruses is blocked at or before viral DNA synthesis in restrictive chicken cells. Virology. 99: 437-42. PMID 229631 DOI: 10.1016/0042-6822(79)90025-4  0.96
1979 Cohen JC, Majors JE, Varmus HE. Organization of mouse mammary tumor virus-specific DNA endogenous to BALB/c mice. Journal of Virology. 32: 483-96. PMID 228072 DOI: 10.1128/Jvi.32.2.483-496.1979  1
1979 Hughes SH, Payvar F, Spector D, Schimke RT, Robinson HL, Payne GS, Bishop JM, Varmus HE. Heterogeneity of genetic loci in chickens: analysis of endogenous viral and nonviral genes by cleavage of DNA with restriction endonucleases. Cell. 18: 347-59. PMID 227605 DOI: 10.1016/0092-8674(79)90054-0  1
1979 Robertson DL, Varmus HE. Structural analysis of the intracellular RNAs of murine mammary tumor virus Journal of Virology. 30: 576-589. PMID 224216 DOI: 10.1128/Jvi.30.2.576-589.1979  1
1979 Martin GS, Radke K, Hughes S, Quintrell N, Bishop JM, Varmus HE. Mutants of Rous sarcoma virus with extensive deletions of the viral genome. Virology. 96: 530-46. PMID 223315 DOI: 10.1016/0042-6822(79)90109-0  1
1979 Craig Cohen J, Shank PR, Morris VL, Cardiff R, Varmus HE. Integration of the DNA of mouse mammary tumor virus in virus-infected normal and neoplastic tissue of the mouse Cell. 16: 333-345. PMID 222456 DOI: 10.1016/0092-8674(79)90010-2  1
1979 Oppermann H, Levinson AD, Varmus HE, Levintow L, Bishop JM. Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src). Proceedings of the National Academy of Sciences of the United States of America. 76: 1804-8. PMID 221907 DOI: 10.1073/Pnas.76.4.1804  1
1979 Cohen JC, Varmus HE. Endogenous mammary tumour virus DNA varies among wild mice and segregates during inbreeding Nature. 278: 418-423. PMID 221817 DOI: 10.1038/278418A0  1
1979 Ringold GM, Shank PR, Varmus HE, Ring J, Yamamoto KR. Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells Proceedings of the National Academy of Sciences of the United States of America. 76: 665-669. PMID 218215 DOI: 10.1073/Pnas.76.2.665  1
1979 Morris VL, Kozak C, Cohen JC, Shank PR, Jolicoeur P, Ruddle F, Varmus HE. Endogenous mouse mammary tumor virus DNA is distributed among multiple mouse chromosomes Virology. 92: 46-55. PMID 217167 DOI: 10.1016/0042-6822(79)90213-7  1
1979 Varmus HE, Shank PR, Hughes SE, Kung HJ, Heasley S, Majors J, Vogt PK, Bishop JM. Synthesis, structure, and integration of the DNA of RNA tumor viruses. Cold Spring Harbor Symposia On Quantitative Biology. 43: 851-64. PMID 90576 DOI: 10.1101/Sqb.1979.043.01.091  1
1978 Hughes SH, Shank PR, Spector DH, Kung HJ, Bishop JM, Varmus HE, Vogt PK, Breitman ML. Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites. Cell. 15: 1397-410. PMID 215325 DOI: 10.1016/0092-8674(78)90064-8  1
1978 Shank PR, Hughes SH, Kung HJ, Majors JE, Quintrell N, Guntaka RV, Bishop JM, Varmus HE. Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. Cell. 15: 1383-95. PMID 215324 DOI: 10.1016/0092-8674(78)90063-6  1
1978 Levinson AD, Oppermann H, Levintow L, Varmus HE, Bishop JM. Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein. Cell. 15: 561-72. PMID 214242 DOI: 10.1016/0092-8674(78)90024-7  1
1978 Spector DH, Varmus HE, Bishop JM. Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates. Proceedings of the National Academy of Sciences of the United States of America. 75: 4102-6. PMID 212733 DOI: 10.1073/Pnas.75.9.4102  1
1978 Fujita DJ, Tal J, Varmus HE, Bishop JM. env Gene of chicken RNA tumor viruses: extent of conservation in cellular and viral genomes. Journal of Virology. 27: 465-74. PMID 212576 DOI: 10.1128/Jvi.27.3.465-474.1978  0.96
1978 Cordell B, Weiss SR, Varmus HE, Bishop JM. At least 104 nucleotides are transposed from the 5' terminus of the avian sarcoma virus genome to the 5' termini of smaller viral mRNAs. Cell. 15: 79-91. PMID 212200 DOI: 10.1016/0092-8674(78)90084-3  0.96
1978 Shank PR, Cohen JC, Varmus HE, Yamamoto KR, Ringold GM. Mapping of linear and circular forms of mouse mammary tumor virus DNA with restriction endonucleases: Evidence for a large specific deletion occurring at high frequency during circularization Proceedings of the National Academy of Sciences of the United States of America. 75: 2112-2116. PMID 209450 DOI: 10.1073/Pnas.75.5.2112  1
1978 Ringold GM, Cohen JC, Ring J, Shank PR, Varmus HE, Yamamoto KR. Mouse mammary tumor virus genes: Regulation of expression by glucocorticoids and structural analysis with restriction endonucleases Journal of Toxicology and Environmental Health. 4: 457-470. PMID 207882 DOI: 10.1080/15287397809529671  1
1978 Varmus HE, Heasley S, Kung HJ, Oppermann H, Smith VC, Bishop JM, Shank PR. Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells. Journal of Molecular Biology. 120: 55-82. PMID 205652 DOI: 10.1016/0022-2836(78)90295-4  1
1978 Spector DH, Baker B, Varmus HE, Bishop JM. Characteristics of cellular RNA related to the transforming gene of avian sarcoma viruses. Cell. 13: 381-6. PMID 203405 DOI: 10.1016/0092-8674(78)90206-4  1
1978 Spector DH, Smith K, Padgett T, McCombe P, Roulland-Dussoix D, Moscovici C, Varmus HE, Bishop JM. Uninfected avian cells contain RNA related to the transforming gene of avian sarcoma viruses. Cell. 13: 371-9. PMID 203404 DOI: 10.1016/0092-8674(78)90205-2  1
1978 Shank PR, Varmus HE. Virus specific DNA in the cytoplasm of avian sarcoma virus infected cells is a precursor to covalently closed circular viral DNA in the nucleus Journal of Virology. 25: 104-114. PMID 202729 DOI: 10.1128/Jvi.25.1.104-104.1978  1
1977 Weiss SR, Varmus HE, Bishop JM. The size and genetic composition of virus-specific RNAs in the cytoplasm of cells producing avian sarcoma-leukosis viruses. Cell. 12: 983-92. PMID 202396 DOI: 10.1016/0092-8674(77)90163-5  0.96
1977 Morris VL, Medeiros E, Ringold GM, Bishop JM, Varmus HE. Comparison of mouse mammary tumor virus-specific DNA in inbred, wild and Asian mice, and in tumors and normal organs from inbred mice. Journal of Molecular Biology. 114: 73-91. PMID 198552 DOI: 10.1016/0022-2836(77)90284-4  0.96
1977 Ringold GM, Yamamoto KR, Bishop JM, Varmus HE. Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA. Proceedings of the National Academy of Sciences of the United States of America. 74: 2879-83. PMID 197523 DOI: 10.1073/Pnas.74.7.2879  0.96
1977 Varmus HE, Padgett T, Heasley S, Simon G, Bishop JM. Cellular functions are required for the synthesis and integration of avian sarcoma virus-specific DNA. Cell. 11: 307-19. PMID 196759 DOI: 10.1016/0092-8674(77)90047-2  0.96
1977 Friedrich R, Kung HJ, Baker B, Varmus HE, Goodman HM, Bishop JM. Characterization of DNA complementary to nucleotide sequences at the 5'-terminus of the avian sarcoma virus genome. Virology. 79: 198-215. PMID 194401 DOI: 10.1016/0042-6822(77)90345-2  0.96
1977 Tal J, Kung HJ, Varmus HE, Bishop JM. Characterization of DNA complementary to nucleotide sequences adjacent to poly(A) at the 3'-terminus of the avian sarcoma virus genome. Virology. 79: 183-97. PMID 194400 DOI: 10.1016/0042-6822(77)90344-0  0.96
1977 Stehelin D, Fujita DJ, Padgett T, Varmus HE, Bishop JM. Detection and enumeration of transformation-defective strains of avian sarcoma virus with molecular hybridization. Virology. 76: 675-84. PMID 190771 DOI: 10.1016/0042-6822(77)90250-1  0.96
1977 Ringold GM, Yamamoto KR, Shank PR, Varmus HE. Mouse mammary tumor virus DNA in infected rat cells: Characterization of unintegrated forms Cell. 10: 19-26. PMID 189933 DOI: 10.1016/0092-8674(77)90135-0  1
1977 Deng CT, Stehelin D, Bishop JM, Varmus HE. Characteristics of virus-specific RNA in avian sarcoma virus-transformed BHK-21 cells and revertants. Virology. 76: 313-30. PMID 189495 DOI: 10.1016/0042-6822(77)90305-1  0.96
1977 Tal J, Fujita DJ, Kawai S, Varmus HE, Bishop JM. Purification of DNA complementary to the env gene of avian sarcoma virus and analysis of relationships among the env genes of avian leukosis-sarcoma viruses. Journal of Virology. 21: 497-505. PMID 189084 DOI: 10.1128/Jvi.21.2.497-505.1977  0.96
1977 Oppermann H, Bishop JM, Varmus HE, Levintow L. A joint produce of the genes gag and pol of avian sarcoma virus: a possible precursor of reverse transcriptase. Cell. 12: 993-1005. PMID 74287 DOI: 10.1016/0092-8674(77)90164-7  1
1976 Stavnezer E, Ringold G, Varmus HE, Bishop JM. RNA complementary to the genome of RNA tumor viruses in virions and virus-producing cells. Journal of Virology. 20: 342-7. PMID 185416 DOI: 10.1128/Jvi.20.1.342-347.1976  0.96
1976 Guntaka RV, Richards OC, Shank PR, Kung HJ, Davidson N, Pritsch E, Bishop JM, Varmus HE. Covalently closed circular DNA of avian sarcoma virus: Purification from nuclei of infected quail tumor cells and measurement by electron microscopy and gel electrophoresis Journal of Molecular Biology. 106: 337-357. PMID 185393 DOI: 10.1016/0022-2836(76)90090-5  1
1976 Friedrich R, Morris VL, Goodman HM, Bishop JM, Varmus HE. Differences between genomes of two strains of mouse mammary tumor virus as shown by partial RNA sequence analysis. Virology. 72: 330-40. PMID 181905 DOI: 10.1016/0042-6822(76)90162-8  0.96
1976 Stehelin D, Varmus HE, Bishop JM, Vogt PK. DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature. 260: 170-3. PMID 176594 DOI: 10.1038/260170A0  0.96
1976 Stehelin D, Guntaka RV, Varmus HE, Bishop JM. Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma viruses. Journal of Molecular Biology. 101: 349-65. PMID 176368 DOI: 10.1016/0022-2836(76)90152-2  1
1976 Varmus HE, Shank PR. Unintegrated viral DNA is synthesized in the cytoplasm of avian sarcoma virus transformed duck cells by viral DNA polymerase Journal of Virology. 18: 567-573. PMID 58074 DOI: 10.1128/Jvi.18.2.567-573.1976  1
1976 Ringold GM, Blair PB, Bishop JM, Varmus HE. Nucleotide sequence homologies among mouse mammary tumor viruses. Virology. 70: 550-3. PMID 57670 DOI: 10.1016/0042-6822(76)90297-X  0.96
1975 Garapin AC, Varmus HE, Faras AJ, Levinson WE, Bishop JM. RNA-directed DNA synthesis by virions of Rous sarcoma virus: further characterization of the templates and the extent of their transcription. Virology. 52: 264-74. PMID 4139806 DOI: 10.1016/0042-6822(73)90414-5  0.72
1975 Kan YW, Dozy AM, Varmus HE, Taylor JM, Holland JP, Lie-Injo LE, Ganesan J, Todd D. Deletion of α-globin genes in haemoglobin-H disease demonstrates multiple α-globin structural loci Nature. 255: 255-256. PMID 1170497 DOI: 10.1038/255255A0  0.4
1975 Ringold GM, Yamamoto KR, Tomkins GM, Bishop M, Varmus HE. Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action. Cell. 6: 299-305. PMID 212202 DOI: 10.1016/0092-8674(75)90181-6  1
1975 Stehelin D, Varmus HE, Bishop JM. Detection of nucleotide sequences associated with transformation by avian sarcoma viruses. Bibliotheca Haematologica. 539-41. PMID 183724 DOI: 10.1159/000399214  0.96
1975 Guntaka RV, Mahy BW, Bishop JM, Varmus HE. Ethidium bromide inhibits appearance of closed circular viral DNA and integration of virus-specific DNA in duck cells infected by avian sarcoma virus. Nature. 253: 507-11. PMID 163973 DOI: 10.1038/253507A0  1
1975 Bishop JM, Deng CT, Faras AJ, Goodman HM, Guntaka RR, Levinson WE, Cordell-Stewart B, Taylor JM, Varmus HE. Transcription of the Rous sarcoma virus genome in vitro and in vivo. Bibliotheca Haematologica. 517-23. PMID 51635 DOI: 10.1159/000397569  1
1975 Varmus HE, Stavnezer J, Medeiros E, Bishop JM. Detection and characterization of RNA tumor virus-specific DNA in cells. Bibliotheca Haematologica. 451-61. PMID 51630 DOI: 10.1159/000397562  0.96
1975 Varmus HE, Guntaka RV, Deng CT, Bishop JM. Synthesis, structure and function of avian sarcoma virus-specific DNA in permissive and nonpermissive cells. Cold Spring Harbor Symposia On Quantitative Biology. 39: 987-96. PMID 50903 DOI: 10.1101/Sqb.1974.039.01.113  1
1975 Ringold G, Lasfargues EY, Bishop JM, Varmus HE. Production of mouse mammary tumor virus by cultured cells in the absence and presence of hormones: assay by molecular hybridization. Virology. 65: 135-47. PMID 49975 DOI: 10.1016/0042-6822(75)90014-8  0.96
1974 Taylor JM, Dozy A, Kan YW, Varmus HE, Lie-Injo LE, Ganesan J, Todd D. Gene deletion as the cause of α thalassaemia: Genetic lesion in homozygous α thalassaemia (hydrops fetalis) Nature. 251: 392-393. PMID 4424635 DOI: 10.1038/251392A0  0.4
1974 Varmus HE, Guntaka RV, Fan WJ, Heasley S, Bishop JM. Synthesis of viral DNA in the cytoplasm of duck embryo fibroblasts and in enucleated cells after infection by avian sarcoma virus. Proceedings of the National Academy of Sciences of the United States of America. 71: 3874-8. PMID 4372595 DOI: 10.1073/Pnas.71.10.3874  1
1974 Bishop JM, Quintrell N, Medeiros E, Varmus HE. Of birds and mice and men: comments on the use of animal models and molecular hybridization in the search for human tumor viruses. Cancer. 34: suppl:1421-6. PMID 4371153 DOI: 10.1002/1097-0142(197410)34:8+<1421::Aid-Cncr2820340813>3.0.Co;2-0  0.96
1974 Quintrell N, Varmus HE, Bishop JM, Nicholson MO, McAllister RM. Homologies among the nucleotide sequences of the genomes of C-type viruses. Virology. 58: 568-75. PMID 4362434 DOI: 10.1016/0042-6822(74)90090-7  0.96
1974 Varmus HE, Heasley S, Bishop JM. Use of DNA-DNA annealing to detect new virus-specific DNA sequences in chicken embryo fibroblasts after infection by avian sarcoma virus. Journal of Virology. 14: 895-903. PMID 4138674 DOI: 10.1128/Jvi.14.4.895-903.1974  0.96
1974 Haase AT, Garapin AC, Faras AJ, Varmus HE, Bishop JM. Characterization of the nucleic acid product of the visna virus RNA dependent DNA polymerase. Virology. 57: 251-8. PMID 4131957 DOI: 10.1016/0042-6822(74)90125-1  0.96
1974 Varmus HE, Heasley S, Bishop JM. Use of DNA-DNA Annealing to Detect New Virus-Specific DNA Sequences in Chicken Embryo Fibroblasts After Infection by Avian Sarcoma Virus Journal of Virology. 14: 895-903. DOI: 10.1128/jvi.14.4.895-903.1974  0.32
1973 Varmus HE, Vogt PK, Bishop JM. Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts. Proceedings of the National Academy of Sciences of the United States of America. 70: 3067-71. PMID 4361674 DOI: 10.1073/Pnas.70.11.3067  0.96
1973 Bishop JM, Jackson N, Levinson WE, Medeiros E, Quintrell N, Varmus HE. The presence and expression of RNA tumor virus genes in normal and infected cells: detection by molecular hybridization. American Journal of Clinical Pathology. 60: 31-43. PMID 4352542 DOI: 10.1093/Ajcp/60.1.31  0.96
1973 Taylor JM, Faras AJ, Varmus HE, Goodman HM, Levinson WE, Bishop JM. Transcription of ribonucleic acid by the ribonucleic acid directed deoxyribonucleic acid polymerase of Rous sarcoma virus and deoxyribonucleic acid polymerase I of Escherichia coli. Biochemistry. 12: 460-7. PMID 4345804 DOI: 10.1021/Bi00727A016  0.96
1973 Varmus HE, Bishop JM, Vogt PK. Appearance of virus-specific DNA in mammalian cells following transformation by Rous sarcoma virus. Journal of Molecular Biology. 74: 613-26. PMID 4125755 DOI: 10.1016/0022-2836(73)90052-1  0.4
1972 Varmus HE, Bishop M, Nowinski RC, Sarker NH. Mammary tumour virus specific nucleotide sequences in mouse DNA Nature New Biology. 238: 189-191. PMID 4340575 DOI: 10.1038/Newbio238189A0  1
1972 Taylor JM, Faras AJ, Varmus HE, Levinson WE, Bishop JM. Ribonucleic acid directed deoxyribonucleic acid synthesis by the purified deoxyribonucleic acid polymerase of Rous sarcoma virus. Characterization of the enzymatic product. Biochemistry. 11: 2343-51. PMID 4337615 DOI: 10.1021/bi00762a021  0.72
1972 Varmus HE, Weiss RA, Friis RR, Levinson W, Bishop JM. Detection of avian tumor virus-specific nucleotide sequences in avian cell DNAs (reassociation kinetics-RNA tumor viruses-gas antigen-Rous sarcoma virus, chick cells). Proceedings of the National Academy of Sciences of the United States of America. 69: 20-4. PMID 4333039 DOI: 10.1073/pnas.69.1.20  0.44
1972 Levinson WE, Varmus HE, Garapin AC, Bishop JM. DNA of Rous sarcoma virus: its nature and significance. Science (New York, N.Y.). 175: 76-8. PMID 4332821 DOI: 10.1126/Science.175.4017.76  0.8
1971 Pastan I, Perlman RL, Emmer M, Varmus HE, DeCrombrugghe B, Chen BP, Parks J. Regulation of gene expression in Escherichia coli by cyclic AMP. Recent Progress in Hormone Research. 27: 421-32. PMID 4336400 DOI: 10.1016/B978-0-12-571127-2.50034-1  1
1971 Varmus HE, Levinson WE, Bishop JM. Extent of transcription by the RNA-dependent DNA polymerase of Rous sarcoma virus. Nature: New Biology. 233: 19-21. PMID 4329249 DOI: 10.1038/Newbio233019A0  0.52
1971 Miller Z, Varmus HE, Parks JS, Perlman RL, Pastan I. Regulation of gal messenger ribonucleic acid synthesis in Escherichia coli by 3',5'-cyclic adenosine monophosphate. The Journal of Biological Chemistry. 246: 2898-903. PMID 4324343  1
1971 Varmus HE, Perlman RL, Pastan I. Regulation of lac transcription in antibiotic-treated E. coli. Nature: New Biology. 230: 41-4. PMID 4324113 DOI: 10.1038/Newbio230041A0  1
1971 De Crombrugghe B, Chen B, Gottesman M, Pastan I, Varmus HE, Emmer M, Perlman RL. Regulation of lac mRNA synthesis in a soluble cell-free system. Nature: New Biology. 230: 37-40. PMID 4324112 DOI: 10.1038/Newbio230037A0  1
1970 Varmus HE, Perlman RL, Pastan I. Regulation of lac transcription in Escherichia coli by cyclic adenosine 3',5'-monophosphate. Studies with deoxyribonucleic acid-ribonucleic acid hybridization and hybridization competition. The Journal of Biological Chemistry. 245: 6366-72. PMID 4320837  1
1970 Varmus HE, Perlman RL, Pastan I. Regulation of lac messenger ribonucleic acid synthesis by cyclic adenosine 3',5'-monophosphate and glucose. The Journal of Biological Chemistry. 245: 2259-67. PMID 4315149  1
1970 de Crombrugghe B, Varmus HE, Perlman RL, Pastan IH. Stimulation of lac mRNA synthesis by cyclic AMP in cell free extracts of Escherichia coli. Biochemical and Biophysical Research Communications. 38: 894-901. PMID 4314384 DOI: 10.1016/0006-291X(70)90805-3  1
1970 Perlman R, Chen B, deCrombrugghe B, Emmer M, Gottesman M, Varmus H, Pastan I. The Regulation of lac Operon Transcription by Cyclic Adenosine 3', 5'-Monophosphate Cold Spring Harbor Symposia On Quantitative Biology. 35: 419-423. DOI: 10.1101/Sqb.1970.035.01.054  0.68
1969 De Crombrugghe B, Perlman RL, Varmus HE, Pastan I. Regulation of inducible enzyme synthesis in Escherichia coli by cyclic adenosine 3', 5'-monophosphate. The Journal of Biological Chemistry. 244: 5828-35. PMID 4310825  1
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