| Year |
Citation |
Score |
| 2023 |
Cook AL, Sur S, Dobbyn L, Watson E, Cohen JD, Ptak B, Lee BS, Paul S, Hsiue E, Popoli M, Vogelstein B, Papadopoulos N, Bettegowda C, Gabrielson K, Zhou S, et al. Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape. Biorxiv : the Preprint Server For Biology. PMID 38234817 DOI: 10.1101/2023.12.28.573594 |
0.333 |
|
| 2023 |
Chan TA, Hermeking H, Lengauer C, Kinzler KW, Vogelstein B. Author Correction: 14-3-3σ is required to prevent mitotic catastrophe after DNA damage. Nature. PMID 37626188 DOI: 10.1038/s41586-023-06446-1 |
0.381 |
|
| 2023 |
Wright KM, DiNapoli SR, Miller MS, Aitana Azurmendi P, Zhao X, Yu Z, Chakrabarti M, Shi W, Douglass J, Hwang MS, Hsiue EH, Mog BJ, Pearlman AH, Paul S, Konig MF, ... ... Vogelstein B, et al. Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nature Communications. 14: 5063. PMID 37604828 DOI: 10.1038/s41467-023-40821-w |
0.785 |
|
| 2023 |
Rincon-Torroella J, Molin MD, Mog B, Han G, Watson E, Wyhs N, Ishiyama S, Ahmedna T, Minn I, Azad NS, Bettegowda C, Papadopoulos N, Kinzler KW, Zhou S, Vogelstein B, et al. ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1. Biorxiv : the Preprint Server For Biology. PMID 37546808 DOI: 10.1101/2023.07.23.550207 |
0.736 |
|
| 2023 |
Lu S, Mattox AK, Aitana Azurmendi P, Christodoulou I, Wright KM, Popoli M, Chen Z, Sur S, Li Y, Bonifant CL, Bettegowda C, Papadopoulos N, Zhou S, Gabelli SB, Vogelstein B, et al. The rapid and highly parallel identification of antibodies with defined biological activities by SLISY. Nature Communications. 14: 17. PMID 36596784 DOI: 10.1038/s41467-022-35668-6 |
0.779 |
|
| 2022 |
Cook AL, Wyhs N, Sur S, Ptak B, Popoli M, Dobbyn L, Papadopoulos T, Bettegowda C, Papadopoulos N, Vogelstein B, Zhou S, Kinzler KW. An isogenic cell line panel for sequence-based screening of targeted anticancer drugs. Iscience. 25: 104437. PMID 35692635 DOI: 10.1016/j.isci.2022.104437 |
0.738 |
|
| 2022 |
Sengupta S, Board NL, Wu F, Moskovljevic M, Douglass J, Zhang J, Reinhold BR, Duke-Cohan J, Yu J, Reed MC, Tabdili Y, Azurmendi A, Fray EJ, Zhang H, Hsiue EH, ... ... Vogelstein B, et al. TCR-mimic bispecific antibodies to target the HIV-1 reservoir. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123406119. PMID 35394875 DOI: 10.1073/pnas.2123406119 |
0.676 |
|
| 2022 |
Pearlman AH, Hwang MS, Konig MF, Hsiue EH, Douglass J, DiNapoli SR, Mog BJ, Bettegowda C, Pardoll DM, Gabelli SB, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Author Correction: Targeting public neoantigens for cancer immunotherapy. Nature Cancer. 2: 865-867. PMID 35122030 DOI: 10.1038/s43018-021-00246-0 |
0.749 |
|
| 2021 |
Pearlman AH, Hwang MS, Konig MF, Hsiue EH, Douglass J, DiNapoli SR, Mog BJ, Bettegowda C, Pardoll DM, Gabelli SB, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Targeting public neoantigens for cancer immunotherapy. Nature Cancer. 2: 487-497. PMID 34676374 DOI: 10.1038/s43018-021-00210-y |
0.777 |
|
| 2021 |
Caushi JX, Zhang J, Ji Z, Vaghasia A, Zhang B, Hsiue EH, Mog BJ, Hou W, Justesen S, Blosser R, Tam A, Anagnostou V, Cottrell TR, Guo H, Chan HY, ... ... Vogelstein B, et al. Author Correction: Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers. Nature. PMID 34608287 DOI: 10.1038/s41586-021-03893-6 |
0.4 |
|
| 2021 |
Hwang MS, Miller MS, Thirawatananond P, Douglass J, Wright KM, Hsiue EH, Mog BJ, Aytenfisu TY, Murphy MB, Aitana Azurmendi P, Skora AD, Pearlman AH, Paul S, DiNapoli SR, Konig MF, ... ... Vogelstein B, et al. Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens. Nature Communications. 12: 5271. PMID 34489470 DOI: 10.1038/s41467-021-25605-4 |
0.806 |
|
| 2021 |
Caushi JX, Zhang J, Ji Z, Vaghasia A, Zhang B, Hsiue EH, Mog BJ, Hou W, Justesen S, Blosser R, Tam A, Anagnostou V, Cottrell TR, Guo H, Chan HY, ... ... Vogelstein B, et al. Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers. Nature. PMID 34290408 DOI: 10.1038/s41586-021-03752-4 |
0.435 |
|
| 2021 |
Hwang MS, Mog BJ, Douglass J, Pearlman AH, Hsiue EH, Paul S, DiNapoli SR, Konig MF, Pardoll DM, Gabelli SB, Bettegowda C, Papadopoulos N, Vogelstein B, Zhou S, Kinzler KW. Targeting loss of heterozygosity for cancer-specific immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33731480 DOI: 10.1073/pnas.2022410118 |
0.779 |
|
| 2021 |
Paul S, Pearlman AH, Douglass J, Mog BJ, Hsiue EH, Hwang MS, DiNapoli SR, Konig MF, Brown PA, Wright KM, Sur S, Gabelli SB, Li Y, Ghiaur G, Pardoll D, ... ... Vogelstein B, et al. TCR beta chain-directed bispecific antibodies for the treatment of T-cell cancers. Science Translational Medicine. PMID 33649188 DOI: 10.1126/scitranslmed.abd3595 |
0.788 |
|
| 2021 |
Hsiue EH, Wright KM, Douglass J, Hwang MS, Mog BJ, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Wang Q, Schaefer A, Miller MS, Skora AD, Azurmendi PA, Murphy MB, ... ... Vogelstein B, et al. Targeting a neoantigen derived from a common mutation. Science (New York, N.Y.). PMID 33649166 DOI: 10.1126/science.abc8697 |
0.836 |
|
| 2021 |
Douglass J, Hsiue EH, Mog BJ, Hwang MS, DiNapoli SR, Pearlman AH, Miller MS, Wright KM, Azurmendi PA, Wang Q, Paul S, Schaefer A, Skora AD, Molin MD, Konig MF, ... ... Vogelstein B, et al. Bispecific antibodies targeting mutant neoantigens. Science Immunology. 6. PMID 33649101 DOI: 10.1126/sciimmunol.abd5515 |
0.811 |
|
| 2021 |
Afsari B, Kuo A, Zhang Y, Li L, Lahouel K, Danilova L, Favorov A, Rosenquist TA, Grollman AP, Kinzler KW, Cope L, Vogelstein B, Tomasetti C. Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer. Elife. 10. PMID 33491650 DOI: 10.7554/eLife.61082 |
0.306 |
|
| 2020 |
Tie J, Vogelstein B, Gibbs P. Circulating Tumor DNA as a Prognostic Marker in Stage III Colon Cancer-Reply. Jama Oncology. PMID 32239186 DOI: 10.1001/Jamaoncol.2020.0289 |
0.339 |
|
| 2020 |
Douville C, Cohen JD, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Schoen RE, Tie J, Gibbs P, Goggins M, Wolfgang CL, Wang TL, Shih IM, Karchin R, ... ... Vogelstein B, et al. Assessing aneuploidy with repetitive element sequencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 32075918 DOI: 10.1073/Pnas.1910041117 |
0.502 |
|
| 2019 |
Lahouel K, Younes L, Danilova L, Giardiello FM, Hruban RH, Groopman J, Kinzler KW, Vogelstein B, Geman D, Tomasetti C. Revisiting the tumorigenesis timeline with a data-driven generative model. Proceedings of the National Academy of Sciences of the United States of America. PMID 31882448 DOI: 10.1073/Pnas.1914589117 |
0.446 |
|
| 2019 |
Miller MS, Douglass J, Hwang MS, Skora AD, Murphy M, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S, Gabelli SB. An engineered antibody fragment targeting mutant β-catenin via Major Histocompatibility Complex I neoantigen presentation. The Journal of Biological Chemistry. PMID 31690625 DOI: 10.1074/Jbc.Ra119.010251 |
0.788 |
|
| 2019 |
Tie J, Cohen JD, Wang Y, Christie M, Simons K, Lee M, Wong R, Kosmider S, Ananda S, McKendrick J, Lee B, Cho JH, Faragher I, Jones IT, Ptak J, ... ... Vogelstein B, et al. Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer. Jama Oncology. PMID 31621801 DOI: 10.1001/Jamaoncol.2019.3616 |
0.344 |
|
| 2019 |
Tomasetti C, Poling J, Roberts NJ, London NR, Pittman ME, Haffner MC, Rizzo A, Baras A, Karim B, Kim A, Heaphy CM, Meeker AK, Hruban RH, Iacobuzio-Donahue CA, Vogelstein B. Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence. Proceedings of the National Academy of Sciences of the United States of America. PMID 31548407 DOI: 10.1073/Pnas.1905722116 |
0.726 |
|
| 2019 |
Wang Q, Douglass J, Hwang MS, Hsiue EH, Mog BJ, Zhang M, Papadopoulos N, Kinzler KW, Zhou S, Vogelstein B. Direct Detection and Quantification of Neo-antigens. Cancer Immunology Research. PMID 31527070 DOI: 10.1158/2326-6066.Cir-19-0107 |
0.324 |
|
| 2019 |
Rodriguez Pena MDC, Springer SU, Taheri D, Li L, Tregnago AC, Eich ML, Eltoum IA, VandenBussche CJ, Papadopoulos N, Kinzler KW, Vogelstein B, Netto GJ. Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal urine cytology. Virchows Archiv : An International Journal of Pathology. PMID 31482302 DOI: 10.1007/S00428-019-02654-1 |
0.312 |
|
| 2019 |
Mattox AK, Bettegowda C, Zhou S, Papadopoulos N, Kinzler KW, Vogelstein B. Applications of liquid biopsies for cancer. Science Translational Medicine. 11. PMID 31462507 DOI: 10.1126/Scitranslmed.Aay1984 |
0.307 |
|
| 2019 |
Reiter JG, Baretti M, Gerold JM, Makohon-Moore AP, Daud A, Iacobuzio-Donahue CA, Azad NS, Kinzler KW, Nowak MA, Vogelstein B. An analysis of genetic heterogeneity in untreated cancers. Nature Reviews. Cancer. PMID 31455892 DOI: 10.1038/S41568-019-0185-X |
0.434 |
|
| 2019 |
Lee B, Lipton L, Cohen J, Tie J, Javed AA, Li L, Goldstein D, Burge M, Cooray P, Nagrial A, Tebbutt NC, Thomson B, Nikfarjam M, Harris M, Haydon A, ... ... Vogelstein B, et al. Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localised pancreatic cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 31250894 DOI: 10.1093/Annonc/Mdz200 |
0.321 |
|
| 2019 |
Wang Y, Li L, Cohen JD, Kinde I, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Tie J, Gibbs P, Tomasetti C, Kinzler KW, Papadopoulos N, Vogelstein B, et al. Prognostic Potential of Circulating Tumor DNA Measurement in Postoperative Surveillance of Nonmetastatic Colorectal Cancer. Jama Oncology. PMID 31070668 DOI: 10.1001/Jamaoncol.2019.0512 |
0.36 |
|
| 2019 |
Eich ML, Rodriguez Pena MDC, Springer SU, Taheri D, Tregnago AC, Salles DC, Bezerra SM, Cunha IW, Fujita K, Ertoy D, Bivalacqua TJ, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, et al. Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31028363 DOI: 10.1038/S41379-019-0276-Y |
0.405 |
|
| 2019 |
Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, ... ... Vogelstein B, et al. Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1 (Journal for Immuno Therapy of Cancer (2019) 7 (40) DOI: 10.1186/s40425-018-0492-x) Journal For Immunotherapy of Cancer. 7: 7. PMID 30841906 DOI: 10.1186/S40425_019_0547_7 |
0.509 |
|
| 2019 |
Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, ... ... Vogelstein B, et al. Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1. Journal For Immunotherapy of Cancer. 7: 63. PMID 30841906 DOI: 10.1186/S40425-019-0547-7 |
0.474 |
|
| 2019 |
Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, ... ... Vogelstein B, et al. Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1. Journal For Immunotherapy of Cancer. 7: 40. PMID 30744692 DOI: 10.1186/S40425-018-0492-X |
0.518 |
|
| 2019 |
Wong R, Tie J, Lee M, Cohen J, Wang Y, Li L, Ma S, Christie M, Kosmider S, Tomasetti C, Papadopoulos N, Kinzler K, Vogelstein B, Gibbs P. The potential role of circulating tumor DNA (ctDNA) in the further investigation of colorectal cancer patients with non-specific findings on standard investigations. International Journal of Cancer. PMID 30628066 DOI: 10.1002/Ijc.32117 |
0.31 |
|
| 2019 |
Paul S, Douglass J, Schaefer A, Hsiue EH, Pearlman A, Mog B, Hwang M, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Targeting MHC-linked wild type p53 with TCR mimic single chain diabody for cancer immunotherapy. Journal of Clinical Oncology. 37: 2524-2524. DOI: 10.1200/Jco.2019.37.15_Suppl.2524 |
0.388 |
|
| 2018 |
Gallia GL, Zhang M, Ning Y, Haffner MC, Batista D, Binder ZA, Bishop JA, Hann CL, Hruban RH, Ishii M, Klein AP, Reh DD, Rooper LM, Salmasi V, Tamargo RJ, ... ... Vogelstein B, et al. Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma. Nature Communications. 9: 5410. PMID 30575736 DOI: 10.1038/S41467-018-07578-Z |
0.352 |
|
| 2018 |
Palsgrove DN, Taheri D, Springer SU, Cowan M, Guner G, Mendoza Rodriguez MA, Del Carmen Rodriguez Pena M, Wang Y, Kinde I, Ricardo BFP, Cunha I, Fujita K, Ertoy D, Kinzler KW, Bivalacqua TJ, ... ... Vogelstein B, et al. Targeted sequencing of Plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations. Human Pathology. PMID 30447301 DOI: 10.1016/J.Humpath.2018.10.033 |
0.449 |
|
| 2018 |
Springer SU, Chen CH, Rodriguez Pena MDC, Li L, Douville C, Wang Y, Cohen JD, Taheri D, Silliman N, Schaefer J, Ptak J, Dobbyn L, Papoli M, Kinde I, Afsari B, ... ... Vogelstein B, et al. Correction: Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy. Elife. 7. PMID 30418154 DOI: 10.7554/Elife.43237 |
0.313 |
|
| 2018 |
Song M, Vogelstein B, Giovannucci EL, Willett WC, Tomasetti C. Cancer prevention: Molecular and epidemiologic consensus. Science (New York, N.Y.). 361: 1317-1318. PMID 30262488 DOI: 10.1126/Science.Aau3830 |
0.33 |
|
| 2018 |
Reiter JG, Makohon-Moore AP, Gerold JM, Heyde A, Attiyeh MA, Kohutek ZA, Tokheim CJ, Brown A, DeBlasio RM, Niyazov J, Zucker A, Karchin R, Kinzler KW, Iacobuzio-Donahue CA, Vogelstein B, et al. Minimal functional driver gene heterogeneity among untreated metastases. Science (New York, N.Y.). 361: 1033-1037. PMID 30190408 DOI: 10.1126/Science.Aat7171 |
0.449 |
|
| 2018 |
Makohon-Moore AP, Matsukuma K, Zhang M, Reiter JG, Gerold JM, Jiao Y, Sikkema L, Attiyeh MA, Yachida S, Sandone C, Hruban RH, Klimstra DS, Papadopoulos N, Nowak MA, Kinzler KW, ... Vogelstein B, et al. Precancerous neoplastic cells can move through the pancreatic ductal system. Nature. PMID 30177826 DOI: 10.1038/S41586-018-0481-8 |
0.338 |
|
| 2018 |
Wang Y, Li L, Douville C, Cohen JD, Yen TT, Kinde I, Sundfelt K, Kjær SK, Hruban RH, Shih IM, Wang TL, Kurman RJ, Springer S, Ptak J, Popoli M, ... ... Vogelstein B, et al. Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers. Science Translational Medicine. 10. PMID 29563323 DOI: 10.1126/Scitranslmed.Aap8793 |
0.522 |
|
| 2018 |
Douville C, Springer S, Kinde I, Cohen JD, Hruban RH, Lennon AM, Papadopoulos N, Kinzler KW, Vogelstein B, Karchin R. Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs). Proceedings of the National Academy of Sciences of the United States of America. PMID 29432176 DOI: 10.1073/Pnas.1717846115 |
0.359 |
|
| 2018 |
Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A, Hruban RH, Wolfgang CL, Goggins MG, Dal Molin M, Wang TL, ... ... Vogelstein B, et al. Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science (New York, N.Y.). PMID 29348365 DOI: 10.1126/Science.Aar3247 |
0.526 |
|
| 2018 |
Lee B, Lipton LR, Cohen J, Tie J, Javed AA, Li L, Goldstein D, Cooray P, Nagrial A, Burge ME, Tebbutt NC, Nikfarjam M, Harris M, Lennon AM, Wolfgang CL, ... ... Vogelstein B, et al. Circulating tumor DNA as a prognostic biomarker in early stage pancreatic cancer. Journal of Clinical Oncology. 36: e16206-e16206. DOI: 10.1200/Jco.2018.36.15_Suppl.E16206 |
0.309 |
|
| 2018 |
Eich M, Springer S, Rodriguez Pena M, Taheri D, Tregnago A, Bezerra S, Cunha I, Fujita K, Ertoy D, Bivalacqua T, Papadopoulos N, Kinzler K, Vogelstein B, Netto G. UroSEEK signature in invasive bladder cancer European Urology Supplements. 17: e2493-e2495. DOI: 10.1016/S1569-9056(18)32978-6 |
0.332 |
|
| 2018 |
Springer S, Rodriguez Pena MDC, Tregnago A, Taheri D, Bezerra S, Cunha I, Fujita K, Baydar D, Bivalacqua T, Papadopoulos N, Kinzler KW, Vogelstein B, Netto G. MP65-14 UROSEEK: A NOVEL NON-INVASIVE MOLECULAR ASSAY FOR SURVEILLANCE OF BLADDER CANCER Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.2080 |
0.334 |
|
| 2018 |
Springer S, Rodriguez Pena MDC, Tregnago A, Taheri D, Bezerra S, Cunha I, Fujita K, Baydar D, Bivalacqua T, Papadopoulos N, Kinzler KW, Vogelstein B, Netto G. MP65-13 UROSEEK: A NOVEL NON-INVASIVE MOLECULAR METHOD FOR EARLY DETECTION OF BLADDER CANCER Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.2079 |
0.315 |
|
| 2017 |
Cohen JD, Javed AA, Thoburn C, Wong F, Tie J, Gibbs P, Schmidt CM, Yip-Schneider MT, Allen PJ, Schattner M, Brand RE, Singhi AD, Petersen GM, Hong SM, Kim SC, ... ... Vogelstein B, et al. Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874546 DOI: 10.1073/Pnas.1704961114 |
0.416 |
|
| 2017 |
Tomasetti C, Durrett R, Kimmel M, Lambert A, Parmigiani G, Zauber A, Vogelstein B. Role of stem-cell divisions in cancer risk. Nature. 548: E13-E14. PMID 28796214 DOI: 10.1038/Nature23302 |
0.306 |
|
| 2017 |
Rodriguez Pena MDC, Tregnago AC, Eich ML, Springer S, Wang Y, Taheri D, Ertoy D, Fujita K, Bezerra SM, Cunha IW, Raspollini MR, Yu L, Bivalacqua TJ, Papadopoulos N, Kinzler KW, ... Vogelstein B, et al. Spectrum of genetic mutations in de novo PUNLMP of the urinary bladder. Virchows Archiv : An International Journal of Pathology. PMID 28597078 DOI: 10.1007/S00428-017-2164-5 |
0.445 |
|
| 2017 |
Le DT, Durham JN, Smith KN, Wang H, Bartlett BR, Aulakh LK, Lu S, Kemberling H, Wilt C, Luber BS, Wong F, Azad NS, Rucki AA, Laheru D, Donehower R, ... ... Vogelstein B, et al. Mismatch-repair deficiency predicts response of solid tumors to PD-1 blockade. Science (New York, N.Y.). PMID 28596308 DOI: 10.1126/Science.Aan6733 |
0.566 |
|
| 2017 |
Tomasetti C, Vogelstein B. On the slope of the regression between stem cell divisions and cancer risk, and the lack of correlation between stem cell divisions and environmental factors-associated cancer risk. Plos One. 12: e0175535. PMID 28520721 DOI: 10.1371/Journal.Pone.0175535 |
0.302 |
|
| 2017 |
Anglesio MS, Papadopoulos N, Ayhan A, Nazeran TM, Noë M, Horlings HM, Lum A, Jones S, Senz J, Seckin T, Ho J, Wu RC, Lac V, Ogawa H, Tessier-Cloutier B, ... ... Vogelstein B, et al. Cancer-Associated Mutations in Endometriosis without Cancer. The New England Journal of Medicine. 376: 1835-1848. PMID 28489996 DOI: 10.1056/Nejmoa1614814 |
0.726 |
|
| 2017 |
Mattox AK, Wang Y, Springer S, Cohen JD, Yegnasubramanian S, Nelson WG, Kinzler KW, Vogelstein B, Papadopoulos N. Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416672 DOI: 10.1073/Pnas.1701382114 |
0.354 |
|
| 2017 |
Tomasetti C, Li L, Vogelstein B. Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention. Science (New York, N.Y.). 355: 1330-1334. PMID 28336671 DOI: 10.1126/Science.Aaf9011 |
0.316 |
|
| 2017 |
Miller MS, Maheshwari S, McRobb FM, Kinzler KW, Amzel LM, Vogelstein B, Gabelli SB. Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design. Bioorganic & Medicinal Chemistry. PMID 28129991 DOI: 10.1016/J.Bmc.2017.01.012 |
0.796 |
|
| 2017 |
Makohon-Moore AP, Zhang M, Reiter JG, Bozic I, Allen B, Kundu D, Chatterjee K, Wong F, Jiao Y, Kohutek ZA, Hong J, Attiyeh M, Javier B, Wood LD, Hruban RH, ... ... Vogelstein B, et al. Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer. Nature Genetics. PMID 28092682 DOI: 10.1038/Ng.3764 |
0.451 |
|
| 2017 |
Lee B, Cohen J, Lipton LR, Tie J, Javed AA, Li L, Goldstein D, Cooray P, Nagrial A, Burge ME, Tebbutt NC, Nikfarjam M, Harris M, O'Broin-Lennon AM, Wolfgang CL, ... ... Vogelstein B, et al. Potential role of circulating tumor DNA (ctDNA) in the early diagnosis and post-operative management of localised pancreatic cancer. Journal of Clinical Oncology. 35: 4101-4101. DOI: 10.1200/Jco.2017.35.15_Suppl.4101 |
0.343 |
|
| 2017 |
Tie J, Cohen J, Wang Y, Li L, Kinde I, Elsaleh H, Wong R, Kosmider S, Yip D, Lee M, Tran B, Burge ME, Goldstein D, Singh MS, Diaz LA, ... ... Vogelstein B, et al. The potential of circulating tumor DNA (ctDNA) to guide adjuvant chemotherapy decision making in locally advanced rectal cancer (LARC). Journal of Clinical Oncology. 35: 3521-3521. DOI: 10.1200/Jco.2017.35.15_Suppl.3521 |
0.305 |
|
| 2017 |
Papadopoulos N, Wang Y, Cohen J, Hruban R, Gibbs P, Tie J, Diaz L, Kinzler K, Vogelstein B. Abstract IA17: Non-invasive detection of somatic mutations in the management of CRC Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-Ia17 |
0.415 |
|
| 2017 |
Vogelstein B. Abstract PL01-03: Earlier detection as a key to lower cancer death rates Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Pl01-03 |
0.374 |
|
| 2017 |
Nickles Fader A, Wang Y, Papadapoulos N, Stone R, Wang T, Tanner E, Shih I, Vogelstein B. Detection of tumor-derived DNA with combination Pap smear and plasma testing in women with primary ovarian cancer: A potential screening test on the horizon? Gynecologic Oncology. 145: 24-25. DOI: 10.1016/J.Ygyno.2017.03.071 |
0.542 |
|
| 2016 |
Tokheim CJ, Papadopoulos N, Kinzler KW, Vogelstein B, Karchin R. Evaluating the evaluation of cancer driver genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911828 DOI: 10.1073/Pnas.1616440113 |
0.378 |
|
| 2016 |
Kinzler K, Vogelstein B. Necessity Is The Mother of Invention: The Development of Digital Genomics. Clinical Chemistry. PMID 27754860 DOI: 10.1373/Clinchem.2016.262741 |
0.338 |
|
| 2016 |
Hoang ML, Chen CH, Chen PC, Roberts NJ, Dickman KG, Yun BH, Turesky RJ, Pu YS, Vogelstein B, Papadopoulos N, Grollman AP, Kinzler KW, Rosenquist T. Aristolochic acid in the etiology of renal cell carcinoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 27555084 DOI: 10.1158/1055-9965.Epi-16-0219 |
0.702 |
|
| 2016 |
Hoang ML, Kinde I, Tomasetti C, McMahon KW, Rosenquist TA, Grollman AP, Kinzler KW, Vogelstein B, Papadopoulos N. Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 27528664 DOI: 10.1073/Pnas.1607794113 |
0.36 |
|
| 2016 |
Nguyen D, Taheri D, Springer S, Cowan M, Guner G, Rodriguez MA, Wang Y, Kinde I, VandenBussche CJ, Olson MT, Ricardo BF, Cunha I, Fujita K, Ertoy D, Kinzler KW, ... ... Vogelstein B, et al. High prevalence of TERT promoter mutations in micropapillary urothelial carcinoma. Virchows Archiv : An International Journal of Pathology. PMID 27520411 DOI: 10.1007/S00428-016-2001-2 |
0.394 |
|
| 2016 |
Tie J, Wang Y, Tomasetti C, Li L, Springer S, Kinde I, Silliman N, Tacey M, Wong HL, Christie M, Kosmider S, Skinner I, Wong R, Steel M, Tran B, ... ... Vogelstein B, et al. Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer. Science Translational Medicine. 8: 346ra92. PMID 27384348 DOI: 10.1126/Scitranslmed.Aaf6219 |
0.313 |
|
| 2016 |
Hao Y, Samuels Y, Li Q, Krokowski D, Guan BJ, Wang C, Jin Z, Dong B, Cao B, Feng X, Xiang M, Xu C, Fink S, Meropol NJ, Xu Y, ... ... Vogelstein B, et al. Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer. Nature Communications. 7: 11971. PMID 27321283 DOI: 10.1038/Ncomms11971 |
0.446 |
|
| 2016 |
Cowan M, Springer S, Nguyen D, Taheri D, Guner G, Mendoza Rodriguez MA, Wang Y, Kinde I, Del Carmen Rodriguez Pena M, VandenBussche CJ, Olson M, Cunha I, Fujita K, Ertoy D, Kinzler K, ... ... Vogelstein B, et al. Detection of TERT promoter mutations in primary adenocarcinoma of the urinary bladder. Human Pathology. PMID 26980028 DOI: 10.1016/J.Humpath.2016.02.009 |
0.397 |
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| 2016 |
Cowan M, Springer S, Nguyen D, Taheri D, Guner G, Rodriguez MA, Wang Y, Kinde I, Bussche CJ, Olson MT, Cunha I, Fujita K, Ertoy D, Bivalacqua TJ, Kinzler K, ... Vogelstein B, et al. High prevalence of TERT promoter mutations in primary squamous cell carcinoma of the urinary bladder. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 26965579 DOI: 10.1038/Modpathol.2016.53 |
0.331 |
|
| 2016 |
Rettig EM, Talbot C, Sausen M, Jones S, Bishop JA, Wood LD, Tokheim C, Niknafs N, Karchin R, Fertig E, Wheelan S, Marchionni L, Considine M, Fakhry C, Papadopoulos N, ... ... Vogelstein B, et al. Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma. Cancer Prevention Research (Philadelphia, Pa.). PMID 26862087 DOI: 10.1158/1940-6207.Capr-15-0316 |
0.388 |
|
| 2016 |
Yachida S, Wood LD, Suzuki M, Takai E, Totoki Y, Kato M, Luchini C, Arai Y, Nakamura H, Hama N, Elzawahry A, Hosoda F, Shirota T, Morimoto N, Hori K, ... ... Vogelstein B, et al. Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma. Cancer Cell. PMID 26806338 DOI: 10.1016/J.Ccell.2015.12.012 |
0.407 |
|
| 2016 |
Robles AI, Traverso G, Zhang M, Roberts NJ, Khan MA, Joseph C, Lauwers GY, Selaru FM, Popoli M, Pittman ME, Ke X, Hruban RH, Meltzer SJ, Kinzler KW, Vogelstein B, et al. Whole-exome Sequencing analyses of Inflammatory Bowel Disease-associated Colorectal Cancers. Gastroenterology. PMID 26764183 DOI: 10.1053/J.Gastro.2015.12.036 |
0.756 |
|
| 2016 |
Le DT, Uram JN, Wang H, Kemberling H, Eyring A, Bartlett B, Goldberg RM, Crocenzi TS, Fisher GA, Lee JJ, Greten TF, Laheru D, Azad NS, Donehower RC, Luber B, ... ... Vogelstein B, et al. PD-1 blockade in mismatch repair deficient non-colorectal gastrointestinal cancers. Journal of Clinical Oncology. 34: 195-195. DOI: 10.1200/Jco.2016.34.4_Suppl.195 |
0.361 |
|
| 2016 |
Tie J, Wang Y, Springer S, Kinde I, Wong H, Kosmider S, Tran B, Christie M, Thomson BN, Wong R, Burge ME, Shannon J, Kotasek D, Field KM, Strausberg R, ... ... Vogelstein B, et al. Serial circulating tumor DNA (ctDNA) and recurrence risk in patients (pts) with resectable colorectal liver metastasis (CLM). Journal of Clinical Oncology. 34: e15131-e15131. DOI: 10.1200/Jco.2016.34.15_Suppl.E15131 |
0.316 |
|
| 2016 |
Tie J, Wang Y, Tomasetti C, Li L, Springer S, Kinde I, Wong R, Kosmider S, Tran B, Desai J, Hayes TM, Haydon AM, Yip D, Christie M, Strausberg R, ... ... Vogelstein B, et al. The potential of circulating tumor DNA (ctDNA) to reshape the design of clinical trials testing adjuvant therapy in patients with early stage cancers. Journal of Clinical Oncology. 34: 3511-3511. DOI: 10.1200/Jco.2016.34.15_Suppl.3511 |
0.365 |
|
| 2016 |
Diaz LA, Uram JN, Wang H, Bartlett B, Kemberling H, Eyring A, Azad NS, Dauses T, Laheru D, Lee JJ, Crocenzi TS, Goldberg RM, Fisher GA, Greten TF, Meyer CF, ... ... Vogelstein B, et al. Programmed death-1 blockade in mismatch repair deficient cancer independent of tumor histology. Journal of Clinical Oncology. 34: 3003-3003. DOI: 10.1200/Jco.2016.34.15_Suppl.3003 |
0.387 |
|
| 2016 |
Le DT, Uram JN, Wang H, Bartlett B, Kemberling H, Eyring A, Azad NS, Laheru D, Donehower RC, Crocenzi TS, Goldberg RM, Fisher GA, Lee JJ, Greten TF, Koshiji M, ... ... Vogelstein B, et al. Programmed death-1 blockade in mismatch repair deficient colorectal cancer. Journal of Clinical Oncology. 34: 103-103. DOI: 10.1200/Jco.2016.34.15_Suppl.103 |
0.356 |
|
| 2016 |
Hoang ML, Kinde I, Tomasetti C, Rosenquist T, Grollman AP, Kinzler KW, Vogelstein B, Papadopoulos N. Abstract NG01: Accumulation of somatic mutations in normal and cancerous tissues with age Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Ng01 |
0.408 |
|
| 2016 |
Reiter JG, Makohon-Moore AP, Gerold JM, Bozic I, Chatterjee K, Iacobuzio-Donahue CA, Vogelstein B, Nowak MA. Abstract 2374: Reconstructing the evolutionary history of metastatic cancers Cancer Research. 76: 2374-2374. DOI: 10.1158/1538-7445.Am2016-2374 |
0.375 |
|
| 2016 |
Sur S, Qiao Y, Fries AC, O’Meally RN, Cole RN, Kinzler KW, Vogelstein B, Zhou S. Abstract 1341: PRINT: A protein bioconjugation method with exquisite N-terminal specificity Cancer Research. 76: 1341-1341. DOI: 10.1158/1538-7445.Am2016-1341 |
0.731 |
|
| 2016 |
Robles AI, Traverso G, Zhang M, Roberts N, Khan MA, Joseph C, Lauwers G, Selaru F, Popoli M, Ke X, Hruban RH, Meltzer SJ, Kinzler KW, Vogelstein B, Harris CC, et al. Abstract 127: The genomic landscapes of inflammatory bowel disease-associated colorectal cancers Cancer Research. 76: 127-127. DOI: 10.1158/1538-7445.Am2016-127 |
0.702 |
|
| 2015 |
Sur S, Qiao Y, Fries A, O'Meally RN, Cole RN, Kinzler KW, Vogelstein B, Zhou S. PRINT: A Protein Bioconjugation Method with Exquisite N-terminal Specificity. Scientific Reports. 5: 18363. PMID 26678960 DOI: 10.1038/Srep18363 |
0.719 |
|
| 2015 |
Roberts NJ, Norris AL, Petersen GM, Bondy ML, Brand R, Gallinger S, Kurtz RC, Olson SH, Rustgi AK, Schwartz AG, Stoffel EM, Syngal S, Zogopoulos G, Ali SZ, Axilbund J, ... ... Vogelstein B, et al. Whole genome sequencing defines the genetic heterogeneity of familial pancreatic cancer. Cancer Discovery. PMID 26658419 DOI: 10.1158/2159-8290.Cd-15-0402 |
0.755 |
|
| 2015 |
Vogelstein B, Kinzler KW. The Path to Cancer --Three Strikes and You're Out. The New England Journal of Medicine. 373: 1895-8. PMID 26559569 DOI: 10.1056/Nejmp1508811 |
0.451 |
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| 2015 |
Maritschnegg E, Wang Y, Pecha N, Horvat R, Van Nieuwenhuysen E, Vergote I, Heitz F, Sehouli J, Kinde I, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Speiser P, Zeillinger R. Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26552420 DOI: 10.1200/Jco.2015.61.3083 |
0.438 |
|
| 2015 |
Karthikeyan S, Potter JJ, Geschwind JF, Sur S, Hamilton JP, Vogelstein B, Kinzler KW, Mezey E, Ganapathy-Kanniappan S. Deregulation of Energy Metabolism Promotes Antifibrotic Effects in Human Hepatic Stellate Cells and Prevents Liver Fibrosis in a Mouse Model. Biochemical and Biophysical Research Communications. PMID 26525850 DOI: 10.1016/J.Bbrc.2015.10.101 |
0.715 |
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| 2015 |
Stern JL, Theodorescu D, Vogelstein B, Papadopoulos N, Cech TR. Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers. Genes & Development. 29: 2219-24. PMID 26515115 DOI: 10.1101/Gad.269498.115 |
0.42 |
|
| 2015 |
Waclaw B, Bozic I, Pittman ME, Hruban RH, Vogelstein B, Nowak MA. A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity. Nature. 525: 261-4. PMID 26308893 DOI: 10.1038/Nature14971 |
0.366 |
|
| 2015 |
Ewing AD, Gacita A, Wood LD, Ma F, Xing D, Kim MS, Manda SS, Abril G, Pereira G, Makohon-Moore A, Looijenga LH, Gillis AJ, Hruban RH, Anders RA, Romans KE, ... ... Vogelstein B, et al. Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution. Genome Research. PMID 26260970 DOI: 10.1101/Gr.196238.115 |
0.372 |
|
| 2015 |
Skora AD, Douglass J, Hwang MS, Tam AJ, Blosser RL, Gabelli SB, Cao J, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 26216968 DOI: 10.1073/Pnas.1511996112 |
0.725 |
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| 2015 |
Wang Y, Springer S, Zhang M, McMahon KW, Kinde I, Dobbyn L, Ptak J, Brem H, Chaichana K, Gallia GL, Gokaslan ZL, Groves ML, Jallo GI, Lim M, Olivi A, ... ... Vogelstein B, et al. Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord. Proceedings of the National Academy of Sciences of the United States of America. PMID 26195750 DOI: 10.1073/Pnas.1511694112 |
0.333 |
|
| 2015 |
Perica K, Bieler JG, Schütz C, Varela JC, Douglass J, Skora A, Chiu YL, Oelke M, Kinzler K, Zhou S, Vogelstein B, Schneck JP. Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy. Acs Nano. 9: 6861-71. PMID 26171764 DOI: 10.1021/Acsnano.5B02829 |
0.339 |
|
| 2015 |
Wang Y, Springer S, Mulvey CL, Silliman N, Schaefer J, Sausen M, James N, Rettig EM, Guo T, Pickering CR, Bishop JA, Chung CH, Califano JA, Eisele DW, Fakhry C, ... ... Vogelstein B, et al. Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas. Science Translational Medicine. 7: 293ra104. PMID 26109104 DOI: 10.1126/Scitranslmed.Aaa8507 |
0.346 |
|
| 2015 |
Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D, Biedrzycki B, Donehower RC, Zaheer A, Fisher GA, Crocenzi TS, ... ... Vogelstein B, et al. PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. The New England Journal of Medicine. 372: 2509-20. PMID 26028255 DOI: 10.1200/Jco.2015.33.18_Suppl.Lba100 |
0.544 |
|
| 2015 |
Tie J, Kinde I, Wang Y, Wong HL, Roebert J, Christie M, Tacey M, Wong R, Singh M, Karapetis CS, Desai J, Tran B, Strausberg RL, Diaz LA, Papadopoulos N, ... ... Vogelstein B, et al. Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 25851626 DOI: 10.1093/Annonc/Mdv177 |
0.361 |
|
| 2015 |
Staedtke V, Bai RY, Sun W, Huang J, Kibler KK, Tyler BM, Gallia GL, Kinzler K, Vogelstein B, Zhou S, Riggins GJ. Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats. Oncotarget. 6: 5536-46. PMID 25849940 DOI: 10.18632/Oncotarget.3627 |
0.324 |
|
| 2015 |
Tomasetti C, Vogelstein B. Cancer risk: role of environment—response Science (New York, N.Y.). 347: 729-731. PMID 25678653 DOI: 10.1126/Science.Aaa6592 |
0.385 |
|
| 2015 |
Tomasetti C, Vogelstein B. Variation in cancer risk among tissues can be explained by the number of stem cell divisions Science. 347: 78-81. PMID 25554788 DOI: 10.1126/Science.1260825 |
0.353 |
|
| 2015 |
Tomasetti C, Marchionni L, Nowak MA, Parmigiani G, Vogelstein B. Only three driver gene mutations are required for the development of lung and colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 112: 118-23. PMID 25535351 DOI: 10.1073/Pnas.1421839112 |
0.463 |
|
| 2015 |
Jiao Y, Lumpkins K, Terhune J, Hruban RH, Klein A, Kinzler KW, Papadopoulos N, Vogelstein B, Strauch E. Intraductal papillary mucinous neoplasm in a neonate with congenital hyperinsulinism and a de novo germline SKIL gene mutation. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 15: 194-6. PMID 25464936 DOI: 10.1016/J.Pan.2014.10.009 |
0.384 |
|
| 2015 |
Llosa NJ, Cruise M, Tam A, Wicks EC, Hechenbleikner EM, Taube JM, Blosser RL, Fan H, Wang H, Luber BS, Zhang M, Papadopoulos N, Kinzler KW, Vogelstein B, Sears CL, et al. The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. Cancer Discovery. 5: 43-51. PMID 25358689 DOI: 10.1158/2159-8290.Cd-14-0863 |
0.546 |
|
| 2015 |
Norris AL, Roberts NJ, Jones S, Wheelan SJ, Papadopoulos N, Vogelstein B, Kinzler KW, Hruban RH, Klein AP, Eshleman JR. Familial and sporadic pancreatic cancer share the same molecular pathogenesis. Familial Cancer. 14: 95-103. PMID 25240578 DOI: 10.1007/S10689-014-9755-Y |
0.758 |
|
| 2015 |
Tie J, Wang Y, Kinde I, Steel M, Elsaleh H, Singh MS, Turner NH, Tran B, Strausberg R, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Gibbs P. Circulating tumor DNA (ctDNA) in nonmetastatic colorectal cancer (CRC): Potential role as a screening tool. Journal of Clinical Oncology. 33: 518-518. DOI: 10.1200/Jco.2015.33.3_Suppl.518 |
0.392 |
|
| 2015 |
Miller M, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Abstract PR02: Targeting PI3K: The PIP2 binding site Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-Pr02 |
0.783 |
|
| 2015 |
Sur S, Chapiro J, Savic LJ, Kaniappan GS, Reyes J, Duran R, Thiruganasambandam SC, Moats CR, Luo W, Ewald AJ, Zhou S, Kinzler KW, Geschwind J, Vogelstein B. Abstract NG06: The Trojan Horse Strategy: Packaging chemotherapeutics can help alleviate toxicity Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Ng06 |
0.748 |
|
| 2015 |
Tomasetti C, Vogelstein B. Abstract LB-054: Normal stem cell divisions, cancer incidence, and driver gene mutations Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-054 |
0.468 |
|
| 2015 |
Llosa NJ, Cruise M, Tam A, Wick E, Hechenbleikner E, Taube J, Blosser L, Fan H, Wang H, Zhang M, Luber B, Papadopoulos N, Kinzler K, Vogelstein B, Sears C, et al. Abstract 451: The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints Cancer Research. 75: 451-451. DOI: 10.1158/1538-7445.Am2015-451 |
0.515 |
|
| 2015 |
Makohon-Moore AP, Zhang M, Reiter JG, Bozic I, Wong F, Jiao Y, Chatterjee K, Nowak MA, Papadopoulos N, Vogelstein B, Kinzler KW, Iacobuzio-Donahue CA. Abstract 4137: Clonal evolution defines the natural history of metastatic pancreatic cancer Cancer Research. 75: 4137-4137. DOI: 10.1158/1538-7445.Am2015-4137 |
0.406 |
|
| 2015 |
Sundfeldt K, Kristjansdottir B, Vogelstein B. Abstract 2839: Specific mutant tumor DNA can be detected in ovarian cystic fluid of an unknown ovarian tumor cyst Cancer Research. 75: 2839-2839. DOI: 10.1158/1538-7445.Am2015-2839 |
0.416 |
|
| 2015 |
Hao Y, Samuels Y, Li Q, Krokowski D, Brunengraber H, Hatzoglou M, Zhang G, Vogelstein B, Wang Z. Abstract 1125: Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancers Cancer Research. 75: 1125-1125. DOI: 10.1158/1538-7445.Am2015-1125 |
0.466 |
|
| 2014 |
Dejea CM, Wick EC, Hechenbleikner EM, White JR, Mark Welch JL, Rossetti BJ, Peterson SN, Snesrud EC, Borisy GG, Lazarev M, Stein E, Vadivelu J, Roslani AC, Malik AA, Wanyiri JW, ... ... Vogelstein B, et al. Microbiota organization is a distinct feature of proximal colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 111: 18321-6. PMID 25489084 DOI: 10.1073/Pnas.1406199111 |
0.532 |
|
| 2014 |
Chapiro J, Sur S, Savic LJ, Ganapathy-Kanniappan S, Reyes J, Duran R, Thiruganasambandam SC, Moats CR, Lin M, Luo W, Tran PT, Herman JM, Semenza GL, Ewald AJ, Vogelstein B, et al. Systemic delivery of microencapsulated 3-bromopyruvate for the therapy of pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 6406-17. PMID 25326230 DOI: 10.1158/1078-0432.Ccr-14-1271 |
0.753 |
|
| 2014 |
Gabelli SB, Echeverria I, Alexander M, Duong-Ly KC, Chaves-Moreira D, Brower ET, Vogelstein B, Amzel LM. Activation of PI3Kα by physiological effectors and by oncogenic mutations: structural and dynamic effects. Biophysical Reviews. 6: 89-95. PMID 25309634 DOI: 10.1007/S12551-013-0131-1 |
0.806 |
|
| 2014 |
Zhang M, Wang Y, Jones S, Sausen M, McMahon K, Sharma R, Wang Q, Belzberg AJ, Chaichana K, Gallia GL, Gokaslan ZL, Riggins GJ, Wolinksy JP, Wood LD, Montgomery EA, ... ... Vogelstein B, et al. Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors. Nature Genetics. 46: 1170-2. PMID 25305755 DOI: 10.1038/Ng.3116 |
0.351 |
|
| 2014 |
Wu X, Renuse S, Sahasrabuddhe NA, Zahari MS, Chaerkady R, Kim MS, Nirujogi RS, Mohseni M, Kumar P, Raju R, Zhong J, Yang J, Neiswinger J, Jeong JS, Newman R, ... ... Vogelstein B, et al. Activation of diverse signalling pathways by oncogenic PIK3CA mutations. Nature Communications. 5: 4961. PMID 25247763 DOI: 10.1038/Ncomms5961 |
0.816 |
|
| 2014 |
Roberts NJ, Zhang L, Janku F, Collins A, Bai RY, Staedtke V, Rusk AW, Tung D, Miller M, Roix J, Khanna KV, Murthy R, Benjamin RS, Helgason T, Szvalb AD, ... ... Vogelstein B, et al. Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses. Science Translational Medicine. 6: 249ra111. PMID 25122639 DOI: 10.1126/Scitranslmed.3008982 |
0.733 |
|
| 2014 |
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Structural basis of nSH2 regulation and lipid binding in PI3Kα. Oncotarget. 5: 5198-208. PMID 25105564 DOI: 10.18632/Oncotarget.2263 |
0.778 |
|
| 2014 |
Kim K, Skora AD, Li Z, Liu Q, Tam AJ, Blosser RL, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 11774-9. PMID 25071169 DOI: 10.1073/Pnas.1410626111 |
0.353 |
|
| 2014 |
Lennon AM, Wolfgang CL, Canto MI, Klein AP, Herman JM, Goggins M, Fishman EK, Kamel I, Weiss MJ, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Hruban RH. The early detection of pancreatic cancer: what will it take to diagnose and treat curable pancreatic neoplasia? Cancer Research. 74: 3381-9. PMID 24924775 DOI: 10.1158/0008-5472.Can-14-0734 |
0.318 |
|
| 2014 |
Bettegowda C, Sausen M, Leary RJ, Kinde I, Wang Y, Agrawal N, Bartlett BR, Wang H, Luber B, Alani RM, Antonarakis ES, Azad NS, Bardelli A, Brem H, Cameron JL, ... ... Vogelstein B, et al. Detection of circulating tumor DNA in early- and late-stage human malignancies. Science Translational Medicine. 6: 224ra24. PMID 24553385 DOI: 10.1126/Scitranslmed.3007094 |
0.621 |
|
| 2014 |
Chan KW, Yu T, Qiao Y, Liu Q, Yang M, Patel H, Liu G, Kinzler KW, Vogelstein B, Bulte JW, van Zijl PC, Hanes J, Zhou S, McMahon MT. A diaCEST MRI approach for monitoring liposomal accumulation in tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 180: 51-9. PMID 24548481 DOI: 10.1016/J.Jconrel.2014.02.005 |
0.317 |
|
| 2014 |
Matthaei H, Wu J, Dal Molin M, Shi C, Perner S, Kristiansen G, Lingohr P, Kalff JC, Wolfgang CL, Kinzler KW, Vogelstein B, Maitra A, Hruban RH. GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "Incipient IPMNs" American Journal of Surgical Pathology. 38: 360-363. PMID 24525507 DOI: 10.1097/Pas.0000000000000117 |
0.357 |
|
| 2014 |
Sur S, Fries AC, Kinzler KW, Zhou S, Vogelstein B. Remote loading of preencapsulated drugs into stealth liposomes. Proceedings of the National Academy of Sciences of the United States of America. 111: 2283-8. PMID 24474802 DOI: 10.1073/Pnas.1324135111 |
0.703 |
|
| 2014 |
Joseph CG, Darrah E, Shah AA, Skora AD, Casciola-Rosen LA, Wigley FM, Boin F, Fava A, Thoburn C, Kinde I, Jiao Y, Papadopoulos N, Kinzler KW, Vogelstein B, Rosen A. Association of the autoimmune disease scleroderma with an immunologic response to cancer. Science (New York, N.Y.). 343: 152-7. PMID 24310608 DOI: 10.1126/Science.1246886 |
0.36 |
|
| 2014 |
Jiao Y, Yonescu R, Offerhaus GJ, Klimstra DS, Maitra A, Eshleman JR, Herman JG, Poh W, Pelosof L, Wolfgang CL, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N, Wood LD. Whole-exome sequencing of pancreatic neoplasms with acinar differentiation. The Journal of Pathology. 232: 428-35. PMID 24293293 DOI: 10.1002/Path.4310 |
0.396 |
|
| 2014 |
Joseph CG, Hwang H, Jiao Y, Wood LD, Kinde I, Wu J, Mandahl N, Luo J, Hruban RH, Diaz LA, He TC, Vogelstein B, Kinzler KW, Mertens F, Papadopoulos N. Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas. Genes, Chromosomes & Cancer. 53: 15-24. PMID 24190505 DOI: 10.1002/Gcc.22114 |
0.414 |
|
| 2014 |
Tie J, Kinde I, Wang Y, Wong H, Skinner I, Wong R, Steel M, Diaz LA, Papadopoulos N, Kosmider S, Yip D, Underhill C, Haydon AM, Christie M, Strausberg R, ... ... Vogelstein B, et al. Circulating tumor DNA (ctDNA) as a marker of recurrence risk in stage II colon cancer (CC). Journal of Clinical Oncology. 32: 11015-11015. DOI: 10.1200/Jco.2014.32.15_Suppl.11015 |
0.33 |
|
| 2014 |
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Abstract LB-326: Structural basis of lipid-binding and regulation in PI3Kα Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-326 |
0.773 |
|
| 2014 |
Bettegowda C, Sausen M, Leary R, Kinde I, Agrawal N, Bartlett B, Wang H, Luber B, Kinzler K, Vogelstein B, Papadopoulos N, Diaz L. Abstract 5606: Detection of circulating tumor DNA in early and late stage human malignancies Cancer Research. 74: 5606-5606. DOI: 10.1158/1538-7445.Am2014-5606 |
0.457 |
|
| 2014 |
Yun J, Kavalier A, Mullarky E, Bosch K, Roper J, Rago C, Paik J, Asara J, Gross S, Vogelstein B, Papadopoulos N, Cantley L. Abstract 2951: Vitamin C is selectively toxic to cancer cells harboring KRAS or BRAF mutations by targeting GAPDH Cancer Research. 74: 2951-2951. DOI: 10.1158/1538-7445.Am2014-2951 |
0.817 |
|
| 2014 |
Staedtke V, Bai R, Kinzler K, Zhou S, Vogelstein B, Riggins G. ET-58 * THE GENETICALLY ENGINEERED CLOSTRIDIUM NOVYI-NT IS EFFICACIOUS IN THE TREATMENT OF INTRACRANIAL GLIOBLASTOMAS Neuro-Oncology. 16: v91-v92. DOI: 10.1093/Neuonc/Nou255.55 |
0.32 |
|
| 2014 |
Bettegowda C, Sausen M, Leary R, Kinde I, Agrawal N, Bartlett B, Wang H, Luber B, Kinzler K, Vogelstein B, Papadopoulos N. Detection Of Circulating Tumor Dna In Early And Late Stage Human Malignancies Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou206.24 |
0.431 |
|
| 2014 |
Erickson B, Dobbin Z, Kinde I, Martin J, Wang Y, Roden R, Huh W, Vogelstein B, Diaz L, Landen C. Testing the accuracy of mutation detection for the prevention of ovarian neoplasia: The TAMPON study Gynecologic Oncology. 133: 116-117. DOI: 10.1016/J.Ygyno.2014.03.307 |
0.34 |
|
| 2014 |
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Structural basis of nSH2 regulation and lipid binding in PI3Kα Oncotarget. 5: 5198-5208. |
0.755 |
|
| 2013 |
Jiao Y, Pawlik TM, Anders RA, Selaru FM, Streppel MM, Lucas DJ, Niknafs N, Guthrie VB, Maitra A, Argani P, Offerhaus GJ, Roa JC, Roberts LR, Gores GJ, Popescu I, ... ... Vogelstein B, et al. Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas. Nature Genetics. 45: 1470-3. PMID 24185509 DOI: 10.1038/Ng.2813 |
0.397 |
|
| 2013 |
Kinde I, Munari E, Faraj SF, Hruban RH, Schoenberg M, Bivalacqua T, Allaf M, Springer S, Wang Y, Diaz LA, Kinzler KW, Vogelstein B, Papadopoulos N, Netto GJ. TERT promoter mutations occur early in urothelial neoplasia and are biomarkers of early disease and disease recurrence in urine. Cancer Research. 73: 7162-7. PMID 24121487 DOI: 10.1158/0008-5472.Can-13-2498 |
0.39 |
|
| 2013 |
Yang J, Hendricks W, Liu G, McCaffery JM, Kinzler KW, Huso DL, Vogelstein B, Zhou S. A nanoparticle formulation that selectively transfects metastatic tumors in mice Proceedings of the National Academy of Sciences of the United States of America. 110: 14717-14722. PMID 23959886 DOI: 10.1073/Pnas.1313330110 |
0.718 |
|
| 2013 |
Hoang ML, Chen CH, Sidorenko VS, He J, Dickman KG, Yun BH, Moriya M, Niknafs N, Douville C, Karchin R, Turesky RJ, Pu YS, Vogelstein B, Papadopoulos N, Grollman AP, et al. Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing Science Translational Medicine. 5. PMID 23926200 DOI: 10.1126/Scitranslmed.3006200 |
0.406 |
|
| 2013 |
Dal Molin M, Matthaei H, Wu J, Blackford A, Debeljak M, Rezaee N, Wolfgang CL, Butturini G, Salvia R, Bassi C, Goggins MG, Kinzler KW, Vogelstein B, Eshleman JR, Hruban RH, et al. Clinicopathological correlates of activating gnas mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas Annals of Surgical Oncology. 20: 3802-3808. PMID 23846778 DOI: 10.1245/S10434-013-3096-1 |
0.402 |
|
| 2013 |
Bozic I, Reiter JG, Allen B, Antal T, Chatterjee K, Shah P, Moon YS, Yaqubie A, Kelly N, Le DT, Lipson EJ, Chapman PB, Diaz LA, Vogelstein B, Nowak MA. Evolutionary dynamics of cancer in response to targeted combination therapy. Elife. 2: e00747. PMID 23805382 DOI: 10.7554/Elife.00747 |
0.349 |
|
| 2013 |
Bettegowda C, Agrawal N, Jiao Y, Wang Y, Wood LD, Rodriguez FJ, Hruban RH, Gallia GL, Binder ZA, Riggins CJ, Salmasi V, Riggins GJ, Reitman ZJ, Rasheed A, Keir S, ... ... Vogelstein B, et al. Exomic sequencing of four rare central nervous system tumor types. Oncotarget. 4: 572-83. PMID 23592488 DOI: 10.18632/Oncotarget.964 |
0.384 |
|
| 2013 |
Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA, Kinzler KW. Cancer genome landscapes. Science (New York, N.Y.). 339: 1546-58. PMID 23539594 DOI: 10.1126/Science.1235122 |
0.472 |
|
| 2013 |
Killela PJ, Reitman ZJ, Jiao Y, Bettegowda C, Agrawal N, Diaz LA, Friedman AH, Friedman H, Gallia GL, Giovanella BC, Grollman AP, He TC, He Y, Hruban RH, Jallo GI, ... ... Vogelstein B, et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proceedings of the National Academy of Sciences of the United States of America. 110: 6021-6. PMID 23530248 DOI: 10.1093/Neuonc/Nou206.18 |
0.603 |
|
| 2013 |
Tomasetti C, Vogelstein B, Parmigiani G. Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation Proceedings of the National Academy of Sciences of the United States of America. 110: 1999-2004. PMID 23345422 DOI: 10.1073/Pnas.1221068110 |
0.4 |
|
| 2013 |
Kinde I, Bettegowda C, Wang Y, Wu J, Agrawal N, Shih IeM, Kurman R, Dao F, Levine DA, Giuntoli R, Roden R, Eshleman JR, Carvalho JP, Marie SK, Papadopoulos N, ... ... Vogelstein B, et al. Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers. Science Translational Medicine. 5: 167ra4. PMID 23303603 DOI: 10.1126/Scitranslmed.3004952 |
0.458 |
|
| 2013 |
Agrawal N, Jiao Y, Sausen M, Leary R, Bettegowda C, Roberts NJ, Bhan S, Ho AS, Khan Z, Bishop J, Westra WH, Wood LD, Hruban RH, Tufano RP, Robinson B, ... ... Vogelstein B, et al. Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS. The Journal of Clinical Endocrinology and Metabolism. 98: E364-9. PMID 23264394 DOI: 10.1210/Jc.2012-2703 |
0.804 |
|
| 2013 |
Sausen M, Leary RJ, Jones S, Wu J, Reynolds CP, Liu X, Blackford A, Parmigiani G, Diaz LA, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE, Hogarty MD. Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma. Nature Genetics. 45: 12-7. PMID 23202128 DOI: 10.1038/Ng.2493 |
0.368 |
|
| 2013 |
Tie J, Kinde I, Wong H, McKendrick JJ, Gibbs P, Singh MS, Karapetis CS, Desai J, Tran B, Roebert JK, Kinzler KW, Vogelstein B. Massively parallel sequencing (MPS) of circulating DNA in patients with metastatic colorectal cancer (mCRC): Prognostic significance and early changes during chemotherapy (CT). Journal of Clinical Oncology. 31: 11015-11015. DOI: 10.1200/Jco.2013.31.15_Suppl.11015 |
0.372 |
|
| 2013 |
Vogelstein B, Kinzler KW. Abstract DL01-01: Cancer Genomes and their Implications for Early Detection Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Dl01-01 |
0.396 |
|
| 2013 |
Yun J, Kavalier A, Roper J, Gross S, Rago C, Papadopoulos N, Vogelstein B, Cantley L. Abstract C60: Vitamin C inhibits the survival and growth of colorectal cancer cells with KRAS or BRAF mutations Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C60 |
0.801 |
|
| 2013 |
Brower ET, Gabelli SB, Wang Q, Chaerkady R, Berndsen CE, Cole RN, Backer JM, Schäfer M, Sinz A, Kinzler KW, Vogelstein B, Amzel LM. Abstract 2225: The molecular architecture of p85α as determined by SAXS and chemical cross-linking. Cancer Research. 73: 2225-2225. DOI: 10.1158/1538-7445.Am2013-2225 |
0.789 |
|
| 2012 |
Leary RJ, Sausen M, Kinde I, Papadopoulos N, Carpten JD, Craig D, O'Shaughnessy J, Kinzler KW, Parmigiani G, Vogelstein B, Diaz LA, Velculescu VE. Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing. Science Translational Medicine. 4: 162ra154. PMID 23197571 DOI: 10.1126/Scitranslmed.3004742 |
0.409 |
|
| 2012 |
Matthaei H, Wu J, Dal Molin M, Debeljak M, Lingohr P, Katabi N, Klimstra DS, Adsay NV, Eshleman JR, Schulick RD, Kinzler KW, Vogelstein B, Hruban RH, Maitra A. GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct Hpb. 14: 677-682. PMID 22954004 DOI: 10.1055/S-0032-1324039 |
0.363 |
|
| 2012 |
Agrawal N, Jiao Y, Bettegowda C, Hutfless SM, Wang Y, David S, Cheng Y, Twaddell WS, Latt NL, Shin EJ, Wang LD, Wang L, Yang W, Velculescu VE, Vogelstein B, et al. Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma. Cancer Discovery. 2: 899-905. PMID 22877736 DOI: 10.1158/2159-8290.Cd-12-0189 |
0.404 |
|
| 2012 |
Jiao Y, Killela PJ, Reitman ZJ, Rasheed AB, Heaphy CM, de Wilde RF, Rodriguez FJ, Rosemberg S, Oba-Shinjo SM, Nagahashi Marie SK, Bettegowda C, Agrawal N, Lipp E, Pirozzi C, Lopez G, ... ... Vogelstein B, et al. Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget. 3: 709-22. PMID 22869205 DOI: 10.18632/Oncotarget.588 |
0.387 |
|
| 2012 |
Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, ... ... Vogelstein B, et al. Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. Plos Genetics. 8: e1002772. PMID 22829774 DOI: 10.1371/Journal.Pgen.1002772 |
0.453 |
|
| 2012 |
Cui Y, Brosnan JA, Blackford AL, Sur S, Hruban RH, Kinzler KW, Vogelstein B, Maitra A, Diaz LA, Iacobuzio-Donahue CA, Eshleman JR. Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6519-30. PMID 22753594 DOI: 10.1158/1078-0432.Ccr-12-0827 |
0.762 |
|
| 2012 |
Diaz LA, Williams RT, Wu J, Kinde I, Hecht JR, Berlin J, Allen B, Bozic I, Reiter JG, Nowak MA, Kinzler KW, Oliner KS, Vogelstein B. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature. 486: 537-40. PMID 22722843 DOI: 10.1038/Nature11219 |
0.394 |
|
| 2012 |
Roberts NJ, Jiao Y, Yu J, Kopelovich L, Petersen GM, Bondy ML, Gallinger S, Schwartz AG, Syngal S, Cote ML, Axilbund J, Schulick R, Ali SZ, Eshleman JR, Velculescu VE, ... ... Vogelstein B, et al. ATM mutations in patients with hereditary pancreatic cancer Cancer Discovery. 2: 41-46. PMID 22585167 DOI: 10.1158/2159-8290.Cd-11-0194 |
0.786 |
|
| 2012 |
Willard MD, Lajiness ME, Wulur IH, Feng B, Swearingen ML, Uhlik MT, Kinzler KW, Velculescu VE, Sjöblom T, Markowitz SD, Powell SM, Vogelstein B, Barber TD. Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes. Molecular Cancer Research : McR. 10: 739-49. PMID 22516348 DOI: 10.1158/1541-7786.Mcr-11-0483 |
0.408 |
|
| 2012 |
Roberts NJ, Vogelstein JT, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. The predictive capacity of personal genome sequencing. Science Translational Medicine. 4: 133ra58. PMID 22472521 DOI: 10.1126/Scitranslmed.3003380 |
0.702 |
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| 2012 |
Kanda M, Matthaei H, Wu J, Hong SM, Yu J, Borges M, Hruban RH, Maitra A, Kinzler K, Vogelstein B, Goggins M. Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia Gastroenterology. 142: 730-733.e9. PMID 22226782 DOI: 10.1053/J.Gastro.2011.12.042 |
0.442 |
|
| 2012 |
Krick EL, Sorenmo KU, Rankin SC, Cheong I, Kobrin B, Thornton K, Kinzler KW, Vogelstein B, Zhou S, Diaz LA. Evaluation of Clostridium novyi-NT spores in dogs with naturally occurring tumors. American Journal of Veterinary Research. 73: 112-8. PMID 22204296 DOI: 10.2460/Ajvr.73.1.112 |
0.67 |
|
| 2012 |
Jones S, Wang TL, Kurman RJ, Nakayama K, Velculescu VE, Vogelstein B, Kinzler KW, Papadopoulos N, Shih IM. Low-grade serous carcinomas of the ovary contain very few point mutations Journal of Pathology. 226: 413-420. PMID 22102435 DOI: 10.1002/Path.3967 |
0.584 |
|
| 2012 |
Jones S, Li M, Williams Parsons D, Zhang X, Wesseling J, Kristel P, Schmidt MK, Markowitz S, Yan H, Bigner D, Hruban RH, Eshleman JR, Iacobuzio-Donahue CA, Goggins M, Maitra A, ... ... Vogelstein B, et al. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types Human Mutation. 33: 100-103. PMID 22009941 DOI: 10.1002/Humu.21633 |
0.437 |
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| 2012 |
Tokino T, Davidson N, Helzlsouer K, Zehnbauer B, Nakamura Y, Vogelstein B, Sidransky D. Absence of germline prohibitin mutations in early-onset breast-cancer. International Journal of Oncology. 3: 769-72. PMID 21573431 DOI: 10.3892/Ijo.3.4.769 |
0.405 |
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| 2012 |
Zhan Q, Eldeiry W, Bae I, Alamo I, Kastan M, Vogelstein B, Fornace A. Similarity of the DNA-damage responsiveness and growth-suppressive properties of waf1/cip1 and gadd45. International Journal of Oncology. 6: 937-46. PMID 21556622 DOI: 10.3892/Ijo.6.5.937 |
0.323 |
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| 2012 |
Wu X, Sahasrabuddhe NA, Renuse S, Zahari S, Chaerkady R, Mohseni M, Yang J, Kim M, Zhong J, Qian J, Zhu H, Vogelstein B, Park BH, Pandey A. Abstract 985: Dissecting PI3K-AKT pathway by phosphoproteomic profiling of PIK3CA knock-in mutants Cancer Research. 72: 985-985. DOI: 10.1158/1538-7445.Am2012-985 |
0.826 |
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| 2012 |
Roberts NJ, Jiao Y, Yu J, Kopelovich L, Petersen GM, Bondy M, Gallinger S, Schwartz AG, Syngal S, Cote ML, Axilbund J, Schulick R, Ali SZ, Eshleman JR, Velculescu V, ... ... Vogelstein B, et al. Abstract 2628: Genome-wide sequencing identifiesATMas a pancreatic cancer susceptibility gene Cancer Research. 72: 2628-2628. DOI: 10.1158/1538-7445.Am2012-2628 |
0.672 |
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| 2012 |
Vogelstein B, Roberts NJ, Vogelstein JT, Parmigiani G, Kinzler KW, Velculescu VE. Response to comments on "The predictive capacity of personal genome sequencing" Science Translational Medicine. 4. DOI: 10.1126/Scitranslmed.3004246 |
0.69 |
|
| 2011 |
Diaz LA, Jiao Y, Shi C, Edil BH, de Wilde R, Klimstra DS, Maitra A, Tang LH, Blackford AL, Velculescu V, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N. Exomic sequencing of pancreatic neuroendocrine tumors: Detection of alterations in chromatin remodeling and mTOR pathway genes. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 10501. PMID 28022366 DOI: 10.1200/Jco.2011.29.15_Suppl.10501 |
0.34 |
|
| 2011 |
Wu J, Jiao Y, Dal Molin M, Maitra A, de Wilde RF, Wood LD, Eshleman JR, Goggins MG, Wolfgang CL, Canto MI, Schulick RD, Edil BH, Choti MA, Adsay V, Klimstra DS, ... ... Vogelstein B, et al. Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways. Proceedings of the National Academy of Sciences of the United States of America. 108: 21188-93. PMID 22158988 DOI: 10.1073/Pnas.1118046108 |
0.448 |
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| 2011 |
Gerstung M, Eriksson N, Lin J, Vogelstein B, Beerenwinkel N. The temporal order of genetic and pathway alterations in tumorigenesis. Plos One. 6: e27136. PMID 22069497 DOI: 10.1371/Journal.Pone.0027136 |
0.695 |
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| 2011 |
Li M, Collins R, Jiao Y, Ouillette P, Bixby D, Erba H, Vogelstein B, Kinzler KW, Papadopoulos N, Malek SN. Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia Blood. 118: 5914-5917. PMID 21989985 DOI: 10.1182/Blood-2011-05-356204 |
0.421 |
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| 2011 |
Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, McLendon R, Riggins G, Velculescu VE, Oba-Shinjo SM, Marie SK, Vogelstein B, Bigner D, et al. Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science (New York, N.Y.). 333: 1453-5. PMID 21817013 DOI: 10.1126/Science.1210557 |
0.563 |
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| 2011 |
Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Treviño L, ... ... Vogelstein B, et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science (New York, N.Y.). 333: 1154-7. PMID 21798897 DOI: 10.1126/Science.1206923 |
0.433 |
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| 2011 |
Wu J, Matthaei H, Maitra A, Dal Molin M, Wood LD, Eshleman JR, Goggins M, Canto MI, Schulick RD, Edil BH, Wolfgang CL, Klein AP, Diaz LA, Allen PJ, Schmidt CM, ... ... Vogelstein B, et al. Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development. Science Translational Medicine. 3: 92ra66. PMID 21775669 DOI: 10.1126/Scitranslmed.3002543 |
0.392 |
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| 2011 |
Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, ... ... Vogelstein B, et al. Altered telomeres in tumors with ATRX and DAXX mutations. Science (New York, N.Y.). 333: 425. PMID 21719641 DOI: 10.1126/Science.1207313 |
0.409 |
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| 2011 |
Zhang X, Reis M, Khoriaty R, Li Y, Ouillette P, Samayoa J, Carter H, Karchin R, Li M, Diaz LA, Velculescu VE, Papadopoulos N, Kinzler KW, Vogelstein B, Malek SN. Sequence analysis of 515 kinase genes in chronic lymphocytic leukemia. Leukemia. 25: 1908-10. PMID 21701494 DOI: 10.1038/Leu.2011.163 |
0.406 |
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| 2011 |
Kinde I, Wu J, Papadopoulos N, Kinzler KW, Vogelstein B. Detection and quantification of rare mutations with massively parallel sequencing Proceedings of the National Academy of Sciences of the United States of America. 108: 9530-9535. PMID 21586637 DOI: 10.1073/Pnas.1105422108 |
0.363 |
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| 2011 |
Holdhoff M, Schmidt K, Diehl F, Aggrawal N, Angenendt P, Romans K, Edelstein DL, Torbenson M, Kinzler KW, Vogelstein B, Choti MA, Diaz LA. Detection of tumor DNA at the margins of colorectal cancer liver metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3551-7. PMID 21531819 DOI: 10.1158/1078-0432.Ccr-10-3087 |
0.369 |
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| 2011 |
He J, Wu J, Jiao Y, Wagner-Johnston N, Ambinder RF, Diaz LA, Kinzler KW, Vogelstein B, Papadopoulos N. IgH gene rearrangements as plasma biomarkers in Non- Hodgkin's lymphoma patients. Oncotarget. 2: 178-85. PMID 21399237 DOI: 10.18632/Oncotarget.235 |
0.308 |
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| 2011 |
Qiao Y, Huang X, Nimmagadda S, Bai R, Staedtke V, Foss CA, Cheong I, Holdhoff M, Kato Y, Pomper MG, Riggins GJ, Kinzler KW, Diaz LA, Vogelstein B, Zhou S. A robust approach to enhance tumor-selective accumulation of nanoparticles. Oncotarget. 2: 59-68. PMID 21378416 DOI: 10.18632/Oncotarget.227 |
0.679 |
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| 2011 |
Reitman ZJ, Jin G, Karoly ED, Spasojevic I, Yang J, Kinzler KW, He Y, Bigner DD, Vogelstein B, Yan H. Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proceedings of the National Academy of Sciences of the United States of America. 108: 3270-5. PMID 21289278 DOI: 10.1073/Pnas.1019393108 |
0.399 |
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| 2011 |
Jiao Y, Shi C, Edil BH, de Wilde RF, Klimstra DS, Maitra A, Schulick RD, Tang LH, Wolfgang CL, Choti MA, Velculescu VE, Diaz LA, Vogelstein B, Kinzler KW, Hruban RH, et al. DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Science (New York, N.Y.). 331: 1199-203. PMID 21252315 DOI: 10.1126/Science.1200609 |
0.436 |
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| 2011 |
Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, ... ... Vogelstein B, et al. The genetic landscape of the childhood cancer medulloblastoma. Science (New York, N.Y.). 331: 435-9. PMID 21163964 DOI: 10.1126/Science.1198056 |
0.696 |
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| 2011 |
Yan H, Reitman ZJ, Jin G, Spasojevic I, He Y, Bigner DD, Karoly ED, Yang J, Kinzler KW, Vogelstein B. Abstract LB-257: Profiling the effects of IDH1 and IDH2 mutants on the glioma cell metabolome Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-257 |
0.356 |
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| 2011 |
Guerrero-Preston R, Agrawal N, Sidransky D, Li RJ, Westra WH, Koch WM, Califano JA, Vogelstein B, Velculescu VE, Papadopoulos N, Kinzler KW. Abstract PR3: Exome sequencing of head and neck squamous cell carcinoma reveals a higher frequency of mutations in TP53 among African Americans Cancer Epidemiology, Biomarkers & Prevention. 20. DOI: 10.1158/1055-9965.Disp-11-Pr3 |
0.41 |
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| 2010 |
Schmidt-Kittler O, Zhu J, Yang J, Liu G, Hendricks W, Lengauer C, Gabelli SB, Kinzler KW, Vogelstein B, Huso DL, Zhou S. PI3Kα inhibitors that inhibit metastasis. Oncotarget. 1: 339-348. PMID 21179398 DOI: 10.18632/Oncotarget.166 |
0.798 |
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| 2010 |
Boca SM, Kinzler KW, Velculescu VE, Vogelstein B, Parmigiani G. Patient-oriented gene set analysis for cancer mutation data Genome Biology. 11. PMID 21092299 DOI: 10.1186/Gb-2010-11-11-R112 |
0.405 |
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| 2010 |
Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, Kamiyama M, Hruban RH, Eshleman JR, Nowak MA, Velculescu VE, Kinzler KW, Vogelstein B, Iacobuzio-Donahue CA. Distant metastasis occurs late during the genetic evolution of pancreatic cancer Nature. 467: 1114-1117. PMID 20981102 DOI: 10.1038/Nature09515 |
0.382 |
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| 2010 |
Bozic I, Antal T, Ohtsuki H, Carter H, Kim D, Chen S, Karchin R, Kinzler KW, Vogelstein B, Nowak MA. Accumulation of driver and passenger mutations during tumor progression Proceedings of the National Academy of Sciences of the United States of America. 107: 18545-18550. PMID 20876136 DOI: 10.1073/Pnas.1010978107 |
0.421 |
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| 2010 |
Jones S, Wang TL, Shih IeM, Mao TL, Nakayama K, Roden R, Glas R, Slamon D, Diaz LA, Vogelstein B, Kinzler KW, Velculescu VE, Papadopoulos N. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science (New York, N.Y.). 330: 228-31. PMID 20826764 DOI: 10.1126/Science.1196333 |
0.655 |
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| 2010 |
Gabelli SB, Huang CH, Mandelker D, Schmidt-Kittler O, Vogelstein B, Amzel LM. Structural effects of oncogenic PI3Kα mutations Current Topics in Microbiology and Immunology. 347: 43-53. PMID 20593314 DOI: 10.1007/82_2010_53 |
0.814 |
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| 2010 |
Leary RJ, Kinde I, Diehl F, Schmidt K, Clouser C, Duncan C, Antipova A, Lee C, McKernan K, De La Vega FM, Kinzler KW, Vogelstein B, Diaz LA, Velculescu VE. Development of personalized tumor biomarkers using massively parallel sequencing. Science Translational Medicine. 2: 20ra14. PMID 20371490 DOI: 10.1126/Scitranslmed.3000702 |
0.401 |
|
| 2010 |
Ericson K, Gan C, Cheong I, Rago C, Samuels Y, Velculescu VE, Kinzler KW, Huso DL, Vogelstein B, Papadopoulos N. Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation. Proceedings of the National Academy of Sciences of the United States of America. 107: 2598-603. PMID 20133737 DOI: 10.1073/Pnas.0914018107 |
0.812 |
|
| 2010 |
Lauring J, Cosgrove DP, Fontana S, Gustin JP, Konishi H, Abukhdeir AM, Garay JP, Mohseni M, Wang GM, Higgins MJ, Gorkin D, Reis M, Vogelstein B, Polyak K, Cowherd M, et al. Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations Oncogene. 29: 2337-2345. PMID 20101210 DOI: 10.1038/Onc.2009.516 |
0.82 |
|
| 2010 |
Gabelli SB, Mandelker D, Schmidt-Kittler O, Vogelstein B, Amzel LM. Somatic mutations in PI3Kα: Structural basis for enzyme activation and drug design Biochimica Et Biophysica Acta - Proteins and Proteomics. 1804: 533-540. PMID 19962457 DOI: 10.1016/J.Bbapap.2009.11.020 |
0.819 |
|
| 2010 |
Schmidt K, Holdhoff M, Diehl F, Angenendt P, Agrawal N, Judge K, Kinzler KW, Vogelstein B, Choti MA, Diaz LA. Mutation-based detection of molecular tumor margins in colorectal liver metastasis. Journal of Clinical Oncology. 28: 3610-3610. DOI: 10.1200/Jco.2010.28.15_Suppl.3610 |
0.366 |
|
| 2010 |
Zhang X, Li M, Ouillette P, Diaz L, Reis M, Velculescu V, Kinzler K, Malek S, Vogelstein B. Identification of Somatically Acquired Gene Mutations In the Kineome and Exome In CLL Blood. 116: 2410-2410. DOI: 10.1182/Blood.V116.21.2410.2410 |
0.444 |
|
| 2010 |
Ericson K, Gan C, Cheong I, Rago C, Samuels Y, Velculescu VE, Kinzler KW, Huso DL, Vogelstein B, Papadopoulos N. Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation (Proceedings of the National Academy of Sciences of the United States of America (2010) 107 (2598-2603) DOI: 10.1073/pnas.0914018107) Proceedings of the National Academy of Sciences of the United States of America. 107: 6551. DOI: 10.1073/Pnas.1002415107 |
0.806 |
|
| 2009 |
Vogelstein B. Cancer genomes and their implications for understanding and managing cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: s1a. PMID 27961878 DOI: 10.1200/Jco.2009.27.15_Suppl.S1A |
0.398 |
|
| 2009 |
Mandelker D, Gabelli SB, Schmidt-Kittler O, Zhu J, Cheong I, Huang CH, Kinzler KW, Vogelstein B, Amzel LM. A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane Proceedings of the National Academy of Sciences of the United States of America. 106: 16996-17001. PMID 19805105 DOI: 10.1073/Pnas.0908444106 |
0.799 |
|
| 2009 |
Yun J, Rago C, Cheong I, Pagliarini R, Angenendt P, Rajagopalan H, Schmidt K, Willson JK, Markowitz S, Zhou S, Diaz LA, Velculescu VE, Lengauer C, Kinzler KW, Vogelstein B, et al. Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. Science (New York, N.Y.). 325: 1555-9. PMID 19661383 DOI: 10.1126/Science.1174229 |
0.815 |
|
| 2009 |
Carter H, Chen S, Isik L, Tyekucheva S, Velculescu VE, Kinzler KW, Vogelstein B, Karchin R. Cancer-specific high-throughput annotation of somatic mutations: Computational prediction of driver missense mutations Cancer Research. 69: 6660-6667. PMID 19654296 DOI: 10.1158/0008-5472.Can-09-1133 |
0.424 |
|
| 2009 |
Guda K, Moinova H, He J, Jamison O, Ravi L, Natale L, Lutterbaugh J, Lawrence E, Lewis S, Willson JKV, Lowe JB, Wiesner GL, Parmigiani G, Barnholtz-Sloan J, Dawson DW, ... ... Vogelstein B, et al. Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers Proceedings of the National Academy of Sciences of the United States of America. 106: 12921-12925. PMID 19617566 DOI: 10.1073/Pnas.0901454106 |
0.469 |
|
| 2009 |
Blackford A, Serrano OK, Wolfgang CL, Parmigiani G, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Cameron JL, ... ... Vogelstein B, et al. SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4674-9. PMID 19584151 DOI: 10.1158/1078-0432.Ccr-09-0227 |
0.708 |
|
| 2009 |
Duncan CG, Leary RJ, Lin JC, Cummins J, Di C, Schaefer CF, Wang TL, Riggins GJ, Edwards J, Bigner D, Kopelovich L, Vogelstein B, Kinzler KW, Velculescu VE, Yan H. Identification of microbial DNA in human cancer. Bmc Medical Genomics. 2: 22. PMID 19426505 DOI: 10.1186/1755-8794-2-22 |
0.799 |
|
| 2009 |
Blackford A, Parmigiani G, Kensler TW, Wolfgang C, Jones S, Zhang X, Parsons DW, Lin JCH, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Klein A, ... ... Vogelstein B, et al. Genetic mutations associated with Cigarette smoking in pancreatic cancer Cancer Research. 69: 3681-3688. PMID 19351817 DOI: 10.1158/0008-5472.Can-09-0015 |
0.387 |
|
| 2009 |
Jones S, Hruban RH, Kamiyama M, Borges M, Zhang X, Parsons DW, Lin JCH, Palmisano E, Brune K, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Parmigiani G, Kern SE, Velculescu VE, ... ... Vogelstein B, et al. Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene Science. 324: 217. PMID 19264984 DOI: 10.1126/Science.1171202 |
0.424 |
|
| 2009 |
Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, Kos I, Batinic-Haberle I, Jones S, Riggins GJ, Friedman H, Friedman A, Reardon D, Herndon J, Kinzler KW, ... ... Vogelstein B, et al. IDH1 and IDH2 mutations in gliomas. The New England Journal of Medicine. 360: 765-73. PMID 19228619 DOI: 10.1056/Nejmoa0808710 |
0.422 |
|
| 2009 |
Sur S, Pagliarini R, Bunz F, Rago C, Diaz LA, Kinzler KW, Vogelstein B, Papadopoulos N. A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53. Proceedings of the National Academy of Sciences of the United States of America. 106: 3964-9. PMID 19225112 DOI: 10.1073/Pnas.0813333106 |
0.822 |
|
| 2009 |
Parmigiani G, Boca S, Lin J, Kinzler KW, Velculescu V, Vogelstein B. Design and analysis issues in genome-wide somatic mutation studies of cancer Genomics. 93: 17-21. PMID 18692126 DOI: 10.1016/J.Ygeno.2008.07.005 |
0.713 |
|
| 2008 |
Diehl F, Schmidt K, Choti MA, Goodman S, Romans K, Thornton K, Kinzler K, Vogelstein B, Diaz LA. Circulating tumor DNA as a cancer biomarker. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 4122. PMID 27950955 DOI: 10.1200/Jco.2008.26.15_Suppl.4122 |
0.43 |
|
| 2008 |
Leary RJ, Lin JC, Cummins J, Boca S, Wood LD, Parsons DW, Jones S, Sjöblom T, Park BH, Parsons R, Willis J, Dawson D, Willson JK, Nikolskaya T, Nikolsky Y, ... ... Vogelstein B, et al. Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 105: 16224-9. PMID 18852474 DOI: 10.1073/Pnas.0808041105 |
0.816 |
|
| 2008 |
Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Kamiyama H, Jimeno A, Hong SM, Fu B, Lin MT, Calhoun ES, Kamiyama M, ... ... Vogelstein B, et al. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science (New York, N.Y.). 321: 1801-6. PMID 18772397 DOI: 10.1126/Science.1164368 |
0.698 |
|
| 2008 |
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Siu IM, Gallia GL, Olivi A, McLendon R, Rasheed BA, Keir S, Nikolskaya T, ... ... Vogelstein B, et al. An integrated genomic analysis of human glioblastoma multiforme. Science (New York, N.Y.). 321: 1807-12. PMID 18772396 DOI: 10.1126/Science.1164382 |
0.705 |
|
| 2008 |
Amzel LM, Huang CH, Mandelker D, Lengauer C, Gabelli SB, Vogelstein B. Structural comparisons of class I phosphoinositide 3-kinases Nature Reviews Cancer. 8: 665-669. PMID 18633356 DOI: 10.1038/Nrc2443 |
0.787 |
|
| 2008 |
Picelli S, Vandrovcova J, Jones S, Djureinovic T, Skoglund J, Zhou XL, Velculescu VE, Vogelstein B, Lindblom A. Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q Bmc Cancer. 8. PMID 18380902 DOI: 10.1186/1471-2407-8-87 |
0.324 |
|
| 2008 |
Jones S, Chen WD, Parmigiani G, Diehl F, Beerenwinkel N, Antal T, Traulsen A, Nowak MA, Siegel C, Velculescu VE, Kinzler KW, Vogelstein B, Willis J, Markowitz SD. Comparative lesion sequencing provides insights into tumor evolution. Proceedings of the National Academy of Sciences of the United States of America. 105: 4283-8. PMID 18337506 DOI: 10.1073/Pnas.0712345105 |
0.457 |
|
| 2008 |
Barber TD, McManus K, Yuen KW, Reis M, Parmigiani G, Shen D, Barrett I, Nouhi Y, Spencer F, Markowitz S, Velculescu VE, Kinzler KW, Vogelstein B, Lengauer C, Hieter P. Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 105: 3443-8. PMID 18299561 DOI: 10.1073/Pnas.0712384105 |
0.629 |
|
| 2008 |
Segal NH, Parsons DW, Peggs KS, Velculescu V, Kinzler KW, Vogelstein B, Allison JP. Epitope landscape in breast and colorectal cancer Cancer Research. 68: 889-892. PMID 18245491 DOI: 10.1158/0008-5472.Can-07-3095 |
0.441 |
|
| 2008 |
Gabelli S, Huang C, Mandelker D, Vogelstein B, Amzel L. Structural basis for the effects of PI3Kalpha oncogenic mutations Acta Crystallographica Section a Foundations of Crystallography. 64: C79-C80. DOI: 10.1107/S0108767308097456 |
0.799 |
|
| 2007 |
Huang CH, Mandelker D, Schmidt-Kittler O, Samuels Y, Velculescu VE, Kinzler KW, Vogelstein B, Gabelli SB, Amzel LM. The structure of a human p110α/p85α complex elucidates the effects of oncogenic PI3Kα mutations Science. 318: 1744-1748. PMID 18079394 DOI: 10.1126/Science.1150799 |
0.805 |
|
| 2007 |
Rago C, Vogelstein B, Bunz F. Genetic knockouts and knockins in human somatic cells Nature Protocols. 2: 2734-2746. PMID 18007609 DOI: 10.1038/Nprot.2007.408 |
0.721 |
|
| 2007 |
Beerenwinkel N, Antal T, Dingli D, Traulsen A, Kinzler KW, Velculescu VE, Vogelstein B, Nowak MA. Genetic progression and the waiting time to cancer. Plos Computational Biology. 3: e225. PMID 17997597 DOI: 10.1371/Journal.Pcbi.0030225 |
0.451 |
|
| 2007 |
Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, ... ... Vogelstein B, et al. The genomic landscapes of human breast and colorectal cancers. Science (New York, N.Y.). 318: 1108-13. PMID 17932254 DOI: 10.1126/science.1145720 |
0.806 |
|
| 2007 |
Diaz LA, Foss CA, Thornton K, Nimmagadda S, Endres CJ, Uzuner O, Seyler TM, Ulrich SD, Conway J, Bettegowda C, Agrawal N, Cheong I, Zhang X, Ladenson PW, Vogelstein BN, ... ... Vogelstein B, et al. Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT. Plos One. 2: e1007. PMID 17925855 DOI: 10.1371/Journal.Pone.0001007 |
0.643 |
|
| 2007 |
Rago C, Huso DL, Diehl F, Karim B, Liu G, Papadopoulos N, Samuels Y, Velculescu VE, Vogelstein B, Kinzler KW, Diaz LA. Serial assessment of human tumor burdens in mice by the analysis of circulating DNA. Cancer Research. 67: 9364-70. PMID 17909045 DOI: 10.1158/0008-5472.Can-07-0605 |
0.716 |
|
| 2007 |
Lin J, Gan CM, Zhang X, Jones S, Sjöblom T, Wood LD, Parsons DW, Papadopoulos N, Kinzler KW, Vogelstein B, Parmigiani G, Velculescu VE. A multidimensional analysis of genes mutated in breast and colorectal cancers Genome Research. 17: 1304-1318. PMID 17693572 DOI: 10.1101/Gr.6431107 |
0.707 |
|
| 2007 |
Plomp M, McCaffery JM, Cheong I, Huang X, Bettegowda C, Kinzler KW, Zhou S, Vogelstein B, Malkin AJ. Spore coat architecture of Clostridium novyi NT spores. Journal of Bacteriology. 189: 6457-68. PMID 17586633 DOI: 10.1128/Jb.00757-07 |
0.652 |
|
| 2007 |
Zhang X, Guo A, Yu J, Possemato A, Chen Y, Zheng W, Polakiewicz RD, Kinzler KW, Vogelstein B, Velculescu VE, Wang ZJ. Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T. Proceedings of the National Academy of Sciences of the United States of America. 104: 4060-4. PMID 17360477 DOI: 10.1073/Pnas.0611665104 |
0.491 |
|
| 2007 |
Lagerstedt Robinson K, Liu T, Vandrovcova J, Halvarsson B, Clendenning M, Frebourg T, Papadopoulos N, Kinzler KW, Vogelstein B, Peltomäki P, Kolodner RD, Nilbert M, Lindblom A. Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics Journal of the National Cancer Institute. 99: 291-299. PMID 17312306 DOI: 10.1093/Jnci/Djk051 |
0.427 |
|
| 2007 |
Parmigiani G, Lin J, Boca SM, Sjöblom T, Jones S, Wood LD, Parsons DW, Barber T, Buckhaults P, Markowitz SD, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, et al. Response to comments on "The consensus coding sequences of human breast and colorectal cancers" Science. 317: 1500d. DOI: 10.1126/Science.1138773 |
0.737 |
|
| 2006 |
Cheong I, Huang X, Bettegowda C, Diaz LA, Kinzler KW, Zhou S, Vogelstein B. A bacterial protein enhances the release and efficacy of liposomal cancer drugs Science. 314: 1308-1311. PMID 17124324 DOI: 10.1126/Science.1130651 |
0.694 |
|
| 2006 |
Bettegowda C, Huang X, Lin J, Cheong I, Kohli M, Szabo SA, Zhang X, Diaz LA, Velculescu VE, Parmigiani G, Kinzler KW, Vogelstein B, Zhou S. The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT Nature Biotechnology. 24: 1573-1580. PMID 17115055 DOI: 10.1038/Nbt1256 |
0.787 |
|
| 2006 |
Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, ... ... Vogelstein B, et al. The consensus coding sequences of human breast and colorectal cancers Science. 314: 268-274. PMID 16959974 DOI: 10.1126/science.1133427 |
0.813 |
|
| 2006 |
Wood LD, Calhoun ES, Silliman N, Ptak J, Szabo S, Powell SM, Riggins GJ, Wang TL, Yan H, Gazdar A, Kern SE, Pennacchio L, Kinzler KW, Vogelstein B, Velculescu VE. Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers Human Mutation.. 27: 1060-1061. PMID 16941478 DOI: 10.1002/Humu.9452 |
0.651 |
|
| 2006 |
Papadopoulos N, Kinzler KW, Vogelstein B. The role of companion diagnostics in the development and use of mutation-targeted cancer therapies Nature Biotechnology. 24: 985-995. PMID 16900147 DOI: 10.1038/Nbt1234 |
0.425 |
|
| 2006 |
McDonald D, Vogelstein B, King MC, Hong WK, Augustin H, Hanahan D, Lippman M. Wanted: cancer boss. Nature. 440: 978-9. PMID 16625165 DOI: 10.1038/440978A |
0.343 |
|
| 2006 |
Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, et al. The colorectal microRNAome. Proceedings of the National Academy of Sciences of the United States of America. 103: 3687-92. PMID 16505370 DOI: 10.1073/Pnas.0511155103 |
0.701 |
|
| 2006 |
Nanda A, Karim B, Peng Z, Liu G, Qiu W, Gan C, Vogelstein B, Croix BS, Kinzler KW, Huso DL. Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors Proceedings of the National Academy of Sciences of the United States of America. 103: 3351-3356. PMID 16492758 DOI: 10.1073/Pnas.0511306103 |
0.324 |
|
| 2005 |
Diehl F, Li M, Dressman D, He Y, Shen D, Szabo S, Diaz LA, Goodman SN, David KA, Juhl H, Kinzler KW, Vogelstein B. Detection and quantification of mutations in the plasma of patients with colorectal tumors. Proceedings of the National Academy of Sciences of the United States of America. 102: 16368-73. PMID 16258065 DOI: 10.1073/Pnas.0507904102 |
0.598 |
|
| 2005 |
Diaz LA, Cheong I, Foss CA, Zhang X, Peters BA, Agrawal N, Bettegowda C, Karim B, Liu G, Khan K, Huang X, Kohli M, Dang LH, Hwang P, Vogelstein A, ... ... Vogelstein B, et al. Pharmacologic and toxicologic evaluation of C. novyi-NT spores. Toxicological Sciences : An Official Journal of the Society of Toxicology. 88: 562-75. PMID 16162850 DOI: 10.1093/Toxsci/Kfi316 |
0.672 |
|
| 2005 |
Parsons DW, Wang TL, Samuels Y, Bardelli A, Cummins JM, DeLong L, Silliman N, Ptak J, Szabo S, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Lengauer C, Velculescu VE. Colorectal cancer: mutations in a signalling pathway. Nature. 436: 792. PMID 16094359 DOI: 10.1038/436792A |
0.814 |
|
| 2005 |
Smith AB, Freeze BS, LaMarche MJ, Sager J, Kinzler KW, Vogelstein B. Discodermolide analogues as the chemical component of combination bacteriolytic therapy. Bioorganic & Medicinal Chemistry Letters. 15: 3623-6. PMID 15979874 DOI: 10.1016/J.Bmcl.2005.05.068 |
0.368 |
|
| 2005 |
Bachman KE, Sager J, Cheong I, Catto M, Bardelli A, Park BH, Vogelstein B, Carotti A, Kinzler KW, Lengauer C. Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine-resistant cancer cells Molecular Cancer Therapeutics. 4: 1026-1030. PMID 15956261 DOI: 10.1158/1535-7163.Mct-05-0038 |
0.762 |
|
| 2005 |
Samuels Y, Diaz LA, Schmidt-Kittler O, Cummins JM, Delong L, Cheong I, Rago C, Huso DL, Lengauer C, Kinzler KW, Vogelstein B, Velculescu VE. Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Cancer Cell. 7: 561-73. PMID 15950905 DOI: 10.1016/J.Ccr.2005.05.014 |
0.832 |
|
| 2005 |
Hienonen T, Sammalkorpi H, Enholm S, Alhopuro P, Barber TD, Lehtonen R, Nupponen NN, Lehtonen H, Salovaara R, Mecklin JP, Järvinen H, Koistinen R, Arango D, Launonen V, Vogelstein B, et al. Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers Cancer Research. 65: 4607-4613. PMID 15930278 DOI: 10.1158/0008-5472.Can-05-0165 |
0.465 |
|
| 2005 |
Peters BA, Diaz LA, Polyak K, Meszler L, Romans K, Guinan EC, Antin JH, Myerson D, Hamilton SR, Vogelstein B, Kinzler KW, Lengauer C. Contribution of bone marrow-derived endothelial cells to human tumor vasculature Nature Medicine. 11: 261-262. PMID 15723071 DOI: 10.1038/Nm1200 |
0.326 |
|
| 2005 |
Bettegowda C, Foss CA, Cheong I, Wang Y, Diaz L, Agrawal N, Fox J, Dick J, Dang LH, Zhou S, Kinzler KW, Vogelstein B, Pomper MG. Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil. Proceedings of the National Academy of Sciences of the United States of America. 102: 1145-50. PMID 15653773 DOI: 10.1073/Pnas.0408861102 |
0.654 |
|
| 2005 |
Michor F, Iwasa Y, Vogelstein B, Lengauer C, Nowak MA. Can chromosomal instability initiate tumorigenesis? Seminars in Cancer Biology. 15: 43-9. PMID 15613287 DOI: 10.1016/J.Semcancer.2004.09.007 |
0.425 |
|
| 2004 |
Barber TD, Vogelstein B, Kinzler KW, Velculescu VE. Somatic mutations of EGFR in colorectal cancers and glioblastomas [6] New England Journal of Medicine. 351: 2883. PMID 15625347 DOI: 10.1056/Nejm200412303512724 |
0.41 |
|
| 2004 |
Bentires-Alj M, Paez JG, David FS, Keilhack H, Halmos B, Naoki K, Maris JM, Richardson A, Bardelli A, Sugarbaker DJ, Richards WG, Du J, Girard L, Minna JD, Loh ML, ... ... Vogelstein B, et al. Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia. Cancer Research. 64: 8816-20. PMID 15604238 DOI: 10.1158/0008-5472.Can-04-1923 |
0.42 |
|
| 2004 |
Nanda A, Buckhaults P, Seaman S, Agrawal N, Boutin P, Shankara S, Nacht M, Teicher B, Stampfl J, Singh S, Vogelstein B, Kinzler KW, St Croix B. Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R. Cancer Research. 64: 8507-11. PMID 15574754 DOI: 10.1158/0008-5472.Can-04-2716 |
0.328 |
|
| 2004 |
Kohli M, Yu J, Seaman C, Bardelli A, Kinzler KW, Vogelstein B, Lengauer C, Zhang L. SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells Proceedings of the National Academy of Sciences of the United States of America. 101: 16897-16902. PMID 15557007 DOI: 10.1073/Pnas.0403405101 |
0.446 |
|
| 2004 |
Agrawal N, Bettegowda C, Cheong I, Geschwind JF, Drake CG, Hipkiss EL, Tatsumi M, Dang LH, Diaz LA, Pomper M, Abusedera M, Wahl RL, Kinzler KW, Zhou S, Huso DL, ... Vogelstein B, et al. Bacteriolytic therapy can generate a potent immune response against experimental tumors Proceedings of the National Academy of Sciences of the United States of America. 101: 15172-15177. PMID 15471990 DOI: 10.1073/Pnas.0406242101 |
0.702 |
|
| 2004 |
Vogelstein B, Kinzler KW. Cancer genes and the pathways they control Nature Medicine. 10: 789-799. PMID 15286780 DOI: 10.1038/Nm1087 |
0.419 |
|
| 2004 |
Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, ... ... Vogelstein B, et al. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science (New York, N.Y.). 304: 1164-6. PMID 15155950 DOI: 10.1126/Science.1096096 |
0.742 |
|
| 2004 |
Cummins JM, Kohli M, Rago C, Kinzler KW, Vogelstein B, Bunz F. X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells. Cancer Research. 64: 3006-8. PMID 15126334 DOI: 10.1158/0008-5472.Can-04-0046 |
0.804 |
|
| 2004 |
Wang Z, Cummins JM, Shen D, Cahill DP, Jallepalli PV, Wang TL, Parsons DW, Traverso G, Awad M, Silliman N, Ptak J, Szabo S, Willson JK, Markowitz SD, Goldberg ML, ... ... Vogelstein B, et al. Three classes of genes mutated in colorectal cancers with chromosomal instability. Cancer Research. 64: 2998-3001. PMID 15126332 DOI: 10.1158/0008-5472.Can-04-0587 |
0.821 |
|
| 2004 |
Cummins JM, Vogelstein B. HAUSP is required for p53 destabilization. Cell Cycle (Georgetown, Tex.). 3: 689-92. PMID 15118411 DOI: 10.4161/Cc.3.6.924 |
0.713 |
|
| 2004 |
Koopmann J, Buckhaults P, Brown DA, Zahurak ML, Sato N, Fukushima N, Sokoll LJ, Chan DW, Yeo CJ, Hruban RH, Breit SN, Kinzler KW, Vogelstein B, Goggins M. Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2386-92. PMID 15073115 DOI: 10.1158/1078-0432.Ccr-03-0165 |
0.331 |
|
| 2004 |
Cummins JM, Rago C, Kohli M, Kinzler KW, Lengauer C, Vogelstein B. Tumour suppression: disruption of HAUSP gene stabilizes p53. Nature. 428: 1 p following 486. PMID 15058298 DOI: 10.1038/Nature02501 |
0.779 |
|
| 2004 |
Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S, Yan H, Gazdar A, Powell SM, Riggins GJ, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE. High frequency of mutations of the PIK3CA gene in human cancers. Science (New York, N.Y.). 304: 554. PMID 15016963 DOI: 10.1126/Science.1096502 |
0.406 |
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| 2004 |
Rajagopalan H, Jallepalli PV, Rago C, Velculescu VE, Kinzler KW, Vogelstein B, Lengauer C. Inactivation of hCDC4 can cause chromosomal instability Nature. 428: 77-81. PMID 14999283 DOI: 10.1038/Nature02313 |
0.738 |
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| 2004 |
Wang TL, Diaz LA, Romans K, Bardelli A, Saha S, Galizia G, Choti M, Donehower R, Parmigiani G, Shih IM, Iacobuzio-Donahue C, Kinzler KW, Vogelstein B, Lengauer C, Velculescu VE. Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients Proceedings of the National Academy of Sciences of the United States of America. 101: 3089-3094. PMID 14970324 DOI: 10.1073/Pnas.0308716101 |
0.577 |
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| 2004 |
Dang LH, Bettegowda C, Agrawal N, Cheong I, Huso D, Frost P, Loganzo F, Greenberger L, Barkoczy J, Pettit GR, Smith AB, Gurulingappa H, Khan S, Parmigiani G, Kinzler KW, ... ... Vogelstein B, et al. Targeting vascular and avascular compartments of tumors with C. novyi-NT and anti-microtubule agents Cancer Biology and Therapy. 3: 326-337. PMID 14739784 DOI: 10.4161/Cbt.3.3.704 |
0.694 |
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| 2004 |
Kohli M, Rago C, Lengauer C, Kinzler KW, Vogelstein B. Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses Nucleic Acids Research. 32: e3. PMID 14704360 DOI: 10.1093/Nar/Gnh009 |
0.733 |
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| 2003 |
Bettegowda C, Dang LH, Abrams R, Huso DL, Dillehay L, Cheong I, Agrawal N, Borzillary S, McCaffery JM, Watson EL, Lin KS, Bunz F, Baidoo K, Pomper MG, Kinzler KW, ... Vogelstein B, et al. Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria. Proceedings of the National Academy of Sciences of the United States of America. 100: 15083-8. PMID 14657371 DOI: 10.1073/Pnas.2036598100 |
0.669 |
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| 2003 |
Rajagopalan H, Nowak MA, Vogelstein B, Lengauer C. The significance of unstable chromosomes in colorectal cancer Nature Reviews Cancer. 3: 695-701. PMID 12951588 DOI: 10.1038/Nrc1165 |
0.312 |
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| 2003 |
Bardelli A, Parsons DW, Silliman N, Ptak J, Szabo S, Saha S, Markowitz S, Willson JKV, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. Mutational analysis of the tyrosine kinome in colorectal cancers Science. 300: 949. PMID 12738854 DOI: 10.1126/Science.1082596 |
0.442 |
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| 2003 |
Jallepalli PV, Lengauer C, Vogelstein B, Bunz F. The Chk2 tumor suppressor is not required for p53 responses in human cancer cells. The Journal of Biological Chemistry. 278: 20475-9. PMID 12654917 DOI: 10.1074/Jbc.M213159200 |
0.401 |
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| 2003 |
Hempen PM, Zhang L, Bansal RK, Iacobuzio-Donahue CA, Murphy KM, Maitra A, Vogelstein B, Whitehead RH, Markowitz SD, Willson JK, Yeo CJ, Hruban RH, Kern SE. Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. Cancer Research. 63: 994-9. PMID 12615714 |
0.355 |
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| 2003 |
Yu J, Wang Z, Kinzler KW, Vogelstein B, Zhang L. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 1931-6. PMID 12574499 DOI: 10.1073/Pnas.2627984100 |
0.494 |
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| 2003 |
Bachman KE, Park BH, Rhee I, Rajagopalan H, Herman JG, Baylin SB, Kinzler KW, Vogelstein B. Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene Cancer Cell. 3: 89-95. PMID 12559178 DOI: 10.1016/S1535-6108(02)00234-9 |
0.539 |
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| 2003 |
Jen J, Vogelstein B. RESPONSE: Tumor Location and Detection of K-Ras Mutations in Stool From Colorectal Cancer Patients Jnci Journal of the National Cancer Institute. 95: 73-73. DOI: 10.1093/Jnci/95.1.73 |
0.385 |
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| 2002 |
Komarova NL, Lengauer C, Vogelstein B, Nowak MA. Dynamics of genetic instability in sporadic and familial colorectal cancer. Cancer Biology & Therapy. 1: 685-92. PMID 12642695 DOI: 10.4161/Cbt.321 |
0.415 |
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| 2002 |
Wang TL, Maierhofer C, Speicher MR, Lengauer C, Vogelstein B, Kinzler KW, Velculescu VE. Digital karyotyping. Proceedings of the National Academy of Sciences of the United States of America. 99: 16156-61. PMID 12461184 DOI: 10.1073/Pnas.202610899 |
0.568 |
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| 2002 |
Nowak MA, Komarova NL, Sengupta A, Jallepalli PV, Shih IeM, Vogelstein B, Lengauer C. The role of chromosomal instability in tumor initiation. Proceedings of the National Academy of Sciences of the United States of America. 99: 16226-31. PMID 12446840 DOI: 10.1073/Pnas.202617399 |
0.393 |
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| 2002 |
Sayed MG, Ahmed AF, Ringold JR, Anderson ME, Bair JL, Mitros FA, Lynch HT, Tinley ST, Petersen GM, Giardiello FM, Vogelstein B, Howe JR. Germline SMAD4 or BMPR1A mutations and phenotype of juvenile polyposis. Annals of Surgical Oncology. 9: 901-6. PMID 12417513 DOI: 10.1007/Bf02557528 |
0.4 |
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| 2002 |
Rajagopalan H, Bardelli A, Lengauer C, Kinzler KW, Vogelstein B, Velculescu VE. RAF/RAS oncogenes and mismatch-repair status Nature. 418: 934. PMID 12198537 DOI: 10.1038/418934A |
0.438 |
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| 2002 |
Chan TA, Wang Z, Dang LH, Vogelstein B, Kinzler KW. Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation. Proceedings of the National Academy of Sciences of the United States of America. 99: 8265-70. PMID 12060769 DOI: 10.1073/Pnas.082240999 |
0.522 |
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| 2002 |
Saha S, Sparks AB, Rago C, Akmaev V, Wang CJ, Vogelstein B, Kinzler KW, Velculescu VE. Using the transcriptome to annotate the genome. Nature Biotechnology. 20: 508-12. PMID 11981567 DOI: 10.1038/Nbt0502-508 |
0.708 |
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| 2002 |
Rhee I, Bachman KE, Park BH, Jair KW, Yen RW, Schuebel KE, Cui H, Feinberg AP, Lengauer C, Kinzler KW, Baylin SB, Vogelstein B. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature. 416: 552-6. PMID 11932749 DOI: 10.1038/416552A |
0.71 |
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| 2002 |
Zawel L, Yu J, Torrance CJ, Markowitz S, Kinzler KW, Vogelstein B, Zhou S. DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities. Proceedings of the National Academy of Sciences of the United States of America. 99: 2848-53. PMID 11880636 DOI: 10.1073/Pnas.261714999 |
0.431 |
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| 2002 |
Wang TL, Rago C, Silliman N, Ptak J, Markowitz S, Willson JK, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. Prevalence of somatic alterations in the colorectal cancer cell genome. Proceedings of the National Academy of Sciences of the United States of America. 99: 3076-80. PMID 11867767 DOI: 10.1073/Pnas.261714699 |
0.816 |
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| 2002 |
Traverso G, Shuber A, Olsson L, Levin B, Johnson C, Hamilton SR, Boynton K, Kinzler KW, Vogelstein B. Detection of proximal colorectal cancers through analysis of faecal DNA. Lancet (London, England). 359: 403-4. PMID 11844514 DOI: 10.1016/S0140-6736(02)07591-8 |
0.407 |
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| 2002 |
Traverso G, Shuber A, Levin B, Johnson C, Olsson L, Schoetz DJ, Hamilton SR, Boynton K, Kinzler KW, Vogelstein B. Detection of APC mutations in fecal DNA from patients with colorectal tumors. The New England Journal of Medicine. 346: 311-20. PMID 11821507 DOI: 10.1056/Nejmoa012294 |
0.398 |
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| 2002 |
Zhou W, Goodman SN, Galizia G, Lieto E, Ferraraccio F, Pignatelli C, Purdie CA, Piris J, Morris R, Harrison DJ, Paty PB, Culliford A, Romans KE, Montgomery EA, Choti MA, ... ... Vogelstein B, et al. Counting alleles to predict recurrence of early-stage colorectal cancers. Lancet (London, England). 359: 219-25. PMID 11812558 DOI: 10.1016/S0140-6736(02)07448-2 |
0.327 |
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| 2002 |
Yan H, Dobbie Z, Gruber SB, Markowitz S, Romans K, Giardiello FM, Kinzler KW, Vogelstein B. Small changes in expression affect predisposition to tumorigenesis Nature Genetics. 30: 25-26. PMID 11743581 DOI: 10.1038/Ng799 |
0.32 |
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| 2001 |
Dang LH, Bettegowda C, Huso DL, Kinzler KW, Vogelstein B. Combination bacteriolytic therapy for the treatment of experimental tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 15155-60. PMID 11724950 DOI: 10.1073/Pnas.251543698 |
0.342 |
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| 2001 |
Saha S, Bardelli A, Buckhaults P, Velculescu VE, Rago C, St Croix B, Romans KE, Choti MA, Lengauer C, Kinzler KW, Vogelstein B. A phosphatase associated with metastasis of colorectal cancer. Science (New York, N.Y.). 294: 1343-6. PMID 11598267 DOI: 10.1126/Science.1065817 |
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| 2001 |
Hwang PM, Bunz F, Yu J, Rago C, Chan TA, Murphy MP, Kelso GF, Smith RA, Kinzler KW, Vogelstein B. Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Nature Medicine. 7: 1111-7. PMID 11590433 DOI: 10.1038/Nm1001-1111 |
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| 2001 |
Vogelstein B, Kinzler KW. Achilles' heel of cancer? Nature. 412: 865-6. PMID 11528457 DOI: 10.1038/35091170 |
0.358 |
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| 2001 |
Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B. PUMA induces the rapid apoptosis of colorectal cancer cells. Molecular Cell. 7: 673-82. PMID 11463391 DOI: 10.1016/S1097-2765(01)00213-1 |
0.433 |
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| 2001 |
Dong SM, Traverso G, Johnson C, Geng L, Favis R, Boynton K, Hibi K, Goodman SN, D'Allessio M, Paty P, Hamilton SR, Sidransky D, Barany F, Levin B, Shuber A, ... ... Vogelstein B, et al. Detecting colorectal cancer in stool with the use of multiple genetic targets. Journal of the National Cancer Institute. 93: 858-65. PMID 11390535 DOI: 10.1093/Jnci/93.11.858 |
0.364 |
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| 2001 |
Howe JR, Bair JL, Sayed MG, Anderson ME, Mitros FA, Petersen GM, Velculescu VE, Traverso G, Vogelstein B. Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis. Nature Genetics. 28: 184-7. PMID 11381269 DOI: 10.1038/88919 |
0.396 |
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| 2001 |
Sparks AB, Peterson SN, Bell C, Loftus BJ, Hocking L, Cahill DP, Frassica FJ, Streeten EA, Levine MA, Fraser CM, Adams MD, Broder S, Venter JC, Kinzler KW, Vogelstein B, et al. Mutation screening of the TNFRSF11A gene encoding receptor activator of NF kappa B (RANK) in familial and sporadic Paget's disease of bone and osteosarcoma. Calcified Tissue International. 68: 151-5. PMID 11351498 DOI: 10.1007/S002230001211 |
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| 2001 |
Zhang L, Yu J, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B. Short mononucleotide repeat sequence variability in mismatch repair-deficient cancers. Cancer Research. 61: 3801-5. PMID 11325855 |
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Bardelli A, Cahill DP, Lederer G, Speicher MR, Kinzler KW, Vogelstein B, Lengauer C. Carcinogen-specific induction of genetic instability. Proceedings of the National Academy of Sciences of the United States of America. 98: 5770-5. PMID 11296254 DOI: 10.1073/Pnas.081082898 |
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| 2001 |
Thiagalingam S, Laken S, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B, Lengauer C. Mechanisms underlying losses of heterozygosity in human colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 98: 2698-702. PMID 11226302 DOI: 10.1073/Pnas.051625398 |
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Shih IM, Wang TL, Traverso G, Romans K, Hamilton SR, Ben-Sasson S, Kinzler KW, Vogelstein B. Top-down morphogenesis of colorectal tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 2640-5. PMID 11226292 DOI: 10.1073/Pnas.051629398 |
0.351 |
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| 2001 |
Park BH, Vogelstein B, Kinzler KW. Genetic disruption of PPARδ decreases the tumorigenicity of human colon cancer cells Proceedings of the National Academy of Sciences of the United States of America. 98: 2598-2603. PMID 11226285 DOI: 10.1073/Pnas.051630998 |
0.611 |
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| 2001 |
Zhou W, Galizia G, Lieto E, Goodman SN, Romans KE, Kinzler KW, Vogelstein B, Choti MA, Montgomery EA. Counting alleles reveals a connection between chromosome 18q loss and vascular invasion. Nature Biotechnology. 19: 78-81. PMID 11135558 DOI: 10.1038/83572 |
0.345 |
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| 2001 |
Marra G, D’Atri S, Yan H, Perrera C, Cannavo E, Vogelstein B, Jiricny J. Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes Cancer Research. 61: 7719-7721. DOI: 10.5167/Uzh-34474 |
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| 2001 |
Hwang PM, Bunz F, Yu J, Rago C, Chan TA, Murphy MP, Kelso GF, Smith RAJ, Kinzler KW, Vogelstein B. Erratum: Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells (Nature Medicine (2001) 7 (1111-1117)) Nature Medicine. 7. DOI: 10.1038/Nm1101-1255A |
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| 2001 |
Gillanders E, Douglas J, Gruber S, Yan H, Vogelstein B, Sood R, Carpten J, Dennis T, Boehnke M, Trent J. Use of experimentally constructed haplotypes in gene mapping studies of hereditary cancers Nature Genetics. 27: 56-56. DOI: 10.1038/87094 |
0.326 |
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| 2000 |
Zhang L, Yu J, Park BH, Kinzler KW, Vogelstein B. Role of BAX in the apoptotic response to anticancer agents. Science (New York, N.Y.). 290: 989-92. PMID 11062132 DOI: 10.1126/Science.290.5493.989 |
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| 2000 |
Velculescu VE, Vogelstein B, Kinzler KW. Analysing uncharted transcriptomes with SAGE. Trends in Genetics : Tig. 16: 423-5. PMID 11050322 DOI: 10.1016/S0168-9525(00)02114-4 |
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| 2000 |
Yan H, Kinzler KW, Vogelstein B. Tech.sight. Genetic testing--present and future. Science (New York, N.Y.). 289: 1890-2. PMID 11012364 DOI: 10.1126/Science.289.5486.1890 |
0.306 |
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| 2000 |
St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW. Genes expressed in human tumor endothelium. Science (New York, N.Y.). 289: 1197-202. PMID 10947988 DOI: 10.1126/Science.289.5482.1197 |
0.717 |
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| 2000 |
Chan TA, Hwang PM, Hermeking H, Kinzler KW, Vogelstein B. Cooperative effects of genes controlling the G(2)/M checkpoint. Genes & Development. 14: 1584-8. PMID 10887152 DOI: 10.1101/Gad.14.13.1584 |
0.548 |
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| 2000 |
Flatt PM, Polyak K, Tang LJ, Scatena CD, Westfall MD, Rubinstein LA, Yu J, Kinzler KW, Vogelstein B, Hill DE, Pietenpol JA. p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest. Cancer Letters. 156: 63-72. PMID 10840161 DOI: 10.1016/S0304-3835(00)00441-9 |
0.417 |
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| 2000 |
Rhee I, Jair KW, Yen RW, Lengauer C, Herman JG, Kinzler KW, Vogelstein B, Baylin SB, Schuebel KE. CpG methylation is maintained in human cancer cells lacking DNMT1. Nature. 404: 1003-7. PMID 10801130 DOI: 10.1038/35010000 |
0.341 |
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| 2000 |
Shih IM, Yu J, He TC, Vogelstein B, Kinzler KW. The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression. Cancer Research. 60: 1671-6. PMID 10749138 |
0.371 |
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| 2000 |
Hermeking H, Rago C, Schuhmacher M, Li Q, Barrett JF, Obaya AJ, O'Connell BC, Mateyak MK, Tam W, Kohlhuber F, Dang CV, Sedivy JM, Eick D, Vogelstein B, Kinzler KW. Identification of CDK4 as a target of c-MYC. Proceedings of the National Academy of Sciences of the United States of America. 97: 2229-34. PMID 10688915 DOI: 10.1073/Pnas.050586197 |
0.701 |
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| 1999 |
Cahill DP, Kinzler KW, Vogelstein B, Lengauer C. Genetic instability and darwinian selection in tumours. Trends in Cell Biology. 9: M57-60. PMID 10611684 DOI: 10.1016/S0168-9525(99)01874-0 |
0.538 |
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| 1999 |
Yu J, Zhang L, Hwang PM, Rago C, Kinzler KW, Vogelstein B. Identification and classification of p53-regulated genes. Proceedings of the National Academy of Sciences of the United States of America. 96: 14517-22. PMID 10588737 DOI: 10.1073/Pnas.96.25.14517 |
0.746 |
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| 1999 |
He TC, Chan TA, Vogelstein B, Kinzler KW. PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell. 99: 335-45. PMID 10555149 DOI: 10.1016/S0092-8674(00)81664-5 |
0.553 |
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| 1999 |
Chan TA, Hermeking H, Lengauer C, Kinzler KW, Vogelstein B. 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature. 401: 616-20. PMID 10524633 DOI: 10.1038/44188 |
0.542 |
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| 1999 |
Da Costa LT, He TC, Yu J, Sparks AB, Morin PJ, Polyak K, Laken S, Vogelstein B, Kinzler KW. CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling Oncogene. 18: 5010-5014. PMID 10490837 DOI: 10.1038/Sj.Onc.1202872 |
0.529 |
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| 1999 |
Vogelstein B, Kinzler KW. Digital PCR. Proceedings of the National Academy of Sciences of the United States of America. 96: 9236-41. PMID 10430926 DOI: 10.1073/Pnas.96.16.9236 |
0.374 |
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| 1999 |
Bunz F, Hwang PM, Torrance C, Waldman T, Zhang Y, Dillehay L, Williams J, Lengauer C, Kinzler KW, Vogelstein B. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. The Journal of Clinical Investigation. 104: 263-9. PMID 10430607 DOI: 10.1172/Jci6863 |
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| 1999 |
Cahill DP, da Costa LT, Carson-Walter EB, Kinzler KW, Vogelstein B, Lengauer C. Characterization of MAD2B and other mitotic spindle checkpoint genes. Genomics. 58: 181-7. PMID 10366450 DOI: 10.1006/Geno.1999.5831 |
0.571 |
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| 1999 |
Laken SJ, Papadopoulos N, Petersen GM, Gruber SB, Hamilton SR, Giardiello FM, Brensinger JD, Vogelstein B, Kinzler KW. Analysis of masked mutations in familial adenomatous polyposis Proceedings of the National Academy of Sciences of the United States of America. 96: 2322-2326. PMID 10051640 DOI: 10.1073/Pnas.96.5.2322 |
0.378 |
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| 1999 |
Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature. 396: 643-9. PMID 9872311 DOI: 10.1038/25292 |
0.345 |
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| 1998 |
Polyak K, Li Y, Zhu H, Lengauer C, Willson JK, Markowitz SD, Trush MA, Kinzler KW, Vogelstein B. Somatic mutations of the mitochondrial genome in human colorectal tumours. Nature Genetics. 20: 291-3. PMID 9806551 DOI: 10.1038/3108 |
0.429 |
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| 1998 |
Fujiwara T, Stolker JM, Watanabe T, Rashid A, Longo P, Eshleman JR, Booker S, Lynch HT, Jass JR, Green JS, Kim H, Jen J, Vogelstein B, Hamilton SR. Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences. The American Journal of Pathology. 153: 1063-78. PMID 9777938 DOI: 10.1016/S0002-9440(10)65651-9 |
0.438 |
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| 1998 |
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, Da Costa LT, Morin PJ, Vogelstein B, Kinzler KW. Identification of c-MYC as a target of the APC pathway Science. 281: 1509-1512. PMID 9727977 DOI: 10.1126/Science.281.5382.1509 |
0.746 |
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| 1998 |
Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW, Vogelstein B. 14-3-3sigma is a p53-regulated inhibitor of G2/M progression. Molecular Cell. 1: 3-11. PMID 9659898 DOI: 10.1016/S1097-2765(00)80002-7 |
0.318 |
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| 1998 |
Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JPJ, Markowitz S, Willson JKV, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma Proceedings of the National Academy of Sciences of the United States of America. 95: 6870-6875. PMID 9618505 DOI: 10.1073/Pnas.95.12.6870 |
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| 1998 |
Kinzler KW, Vogelstein B. Landscaping the cancer terrain. Science (New York, N.Y.). 280: 1036-7. PMID 9616081 DOI: 10.1126/Science.280.5366.1036 |
0.392 |
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| 1998 |
Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B. Mutations of mitotic checkpoint genes in human cancers. Nature. 392: 300-3. PMID 9521327 DOI: 10.1038/32688 |
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| 1998 |
Nicolaides NC, Littman SJ, Modrich P, Kinzler KW, Vogelstein B. A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype Molecular and Cellular Biology. 18: 1635-1641. PMID 9488480 DOI: 10.1128/Mcb.18.3.1635 |
0.448 |
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| 1998 |
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, Vogelstein B. A simplified system for generating recombinant adenoviruses. Proceedings of the National Academy of Sciences of the United States of America. 95: 2509-14. PMID 9482916 |
0.327 |
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| 1998 |
Zhou S, Buckhaults P, Zawel L, Bunz F, Riggins G, Dai JL, Kern SE, Kinzler KW, Vogelstein B. Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 2412-6. PMID 9482899 DOI: 10.1073/Pnas.95.5.2412 |
0.33 |
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| 1998 |
Chan TA, Morin PJ, Vogelstein B, Kinzler KW. Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 95: 681-6. PMID 9435252 DOI: 10.1073/Pnas.95.2.681 |
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| 1997 |
Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B. A model for p53-induced apoptosis. Nature. 389: 300-5. PMID 9305847 DOI: 10.1038/38525 |
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| 1997 |
Waldman T, Zhang Y, Dillehay L, Yu J, Kinzler K, Vogelstein B, Williams J. Cell-cycle arrest versus cell death in cancer therapy. Nature Medicine. 3: 1034-6. PMID 9288734 DOI: 10.1038/Nm0997-1034 |
0.495 |
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| 1997 |
Laken SJ, Petersen GM, Gruber SB, Oddoux C, Ostrer H, Giardiello FM, Hamilton SR, Hampel H, Markowitz A, Klimstra D, Jhanwar S, Winawer S, Offit K, Luce MC, Kinzler KW, ... Vogelstein B, et al. Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC Nature Genetics. 17: 79-83. PMID 9288102 DOI: 10.1038/Ng0997-79 |
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| 1997 |
Giardiello FM, Petersen GM, Piantadosi S, Gruber SB, Traboulsi EI, Offerhaus GJA, Muro K, Krush AJ, Booker SV, Luce MC, Laken SJ, Kinzler KW, Vogelstein B, Hamilton SR. APC gene mutations and extraintestinal phenotype of familial adenomatous polyposis Gut. 40: 521-525. PMID 9176082 DOI: 10.1136/Gut.40.4.521 |
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| 1997 |
Kinzler KW, Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers. Nature. 386: 761, 763. PMID 9126728 DOI: 10.1038/386761A0 |
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| 1997 |
Lengauer C, Kinzler KW, Vogelstein B. DNA methylation and genetic instability in colorectal cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 2545-50. PMID 9122232 DOI: 10.1073/Pnas.94.6.2545 |
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| 1997 |
Lengauer C, Kinzler KW, Vogelstein B. Genetic instability in colorectal cancers. Nature. 386: 623-7. PMID 9121588 DOI: 10.1038/386623A0 |
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| 1997 |
Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC Science. 275: 1787-1790. PMID 9065402 DOI: 10.1126/Science.275.5307.1787 |
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| 1997 |
Dunlop MG, Farrington SM, Carothers AD, Wyllie AH, Sharp L, Burn J, Liu B, Kinzler KW, Vogelstein B. Cancer risk associated with germline DNA mismatch repair gene mutations. Human Molecular Genetics. 6: 105-10. PMID 9002677 DOI: 10.1093/Hmg/6.1.105 |
0.403 |
|
| 1997 |
Nicolaides NC, Palombo F, Kinzler KW, Vogelstein B, Jiricny J. Molecular cloning of the N-terminus of GTBP. Genomics. 31: 395-7. PMID 8838326 DOI: 10.1006/Geno.1996.0067 |
0.379 |
|
| 1996 |
Huang J, Papadopoulos N, McKinley AJ, Farrington SM, Curtis LJ, Wyllie AH, Zheng S, Willson JK, Markowitz SD, Morin P, Kinzler KW, Vogelstein B, Dunlop MG. APC mutations in colorectal tumors with mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America. 93: 9049-54. PMID 8799152 DOI: 10.1073/Pnas.93.17.9049 |
0.42 |
|
| 1996 |
Beazer-Barclay Y, Levy DB, Moser AR, Dove WF, Hamilton SR, Vogelstein B, Kinzler KW. Sulindac suppresses tumorigenesis in the Min mouse. Carcinogenesis. 17: 1757-60. PMID 8761438 DOI: 10.1093/Carcin/17.8.1757 |
0.317 |
|
| 1996 |
Polyak K, Waldman T, He TC, Kinzler KW, Vogelstein B. Genetic determinants of p53-induced apoptosis and growth arrest. Genes & Development. 10: 1945-52. PMID 8756351 DOI: 10.1101/Gad.10.15.1945 |
0.305 |
|
| 1996 |
Morin PJ, Vogelstein B, Kinzler KW. Apoptosis and APC in colorectal tumorigenesis Proceedings of the National Academy of Sciences of the United States of America. 93: 7950-7954. PMID 8755583 DOI: 10.1073/Pnas.93.15.7950 |
0.433 |
|
| 1996 |
Pietenpol JA, Lengauer C, Jordan J, Kinzler KW, Vogelstein B. Mammalian cells resistant to tumor suppressor genes Proceedings of the National Academy of Sciences of the United States of America. 93: 8390-8394. PMID 8710881 DOI: 10.1073/Pnas.93.16.8390 |
0.338 |
|
| 1996 |
Thiagalingam S, Lengauer C, Leach FS, Schutte M, Hahn SA, Overhauser J, Willson JK, Markowitz S, Hamilton SR, Kern SE, Kinzler KW, Vogelstein B. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nature Genetics. 13: 343-6. PMID 8673134 DOI: 10.1038/Ng0796-343 |
0.367 |
|
| 1996 |
Nicolaides NC, Kinzler KW, Vogelstein B. Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene. Genomics. 29: 329-34. PMID 8666379 DOI: 10.1006/Geno.1995.9997 |
0.375 |
|
| 1996 |
Waldman T, Lengauer C, Kinzler KW, Vogelstein B. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature. 381: 713-6. PMID 8649519 DOI: 10.1038/381713A0 |
0.312 |
|
| 1996 |
Da Costa LT, Jen J, He TC, Chan TA, Kinzler KW, Vogelstein B. Converting cancer genes into killer genes. Proceedings of the National Academy of Sciences of the United States of America. 93: 4192-6. PMID 8633039 DOI: 10.1073/Pnas.93.9.4192 |
0.57 |
|
| 1996 |
Nicolaides NC, Carter KC, Shell BK, Papadopoulos N, Vogelstein B, Kinzler KW. Genomic organization of the human PMS2 gene family. Genomics. 30: 195-206. PMID 8586419 DOI: 10.1006/Geno.1995.9885 |
0.348 |
|
| 1996 |
Liu B, Parsons R, Papadopoulos N, Nicolaides NC, Lynch HT, Watson P, Jass JR, Dunlop M, Wyllie A, Peltomäki P, de la Chapelle A, Hamilton SR, Vogelstein B, Kinzler KW. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nature Medicine. 2: 169-74. PMID 8574961 DOI: 10.1038/Nm0296-169 |
0.425 |
|
| 1996 |
Kinzler KW, Vogelstein B. Life (and death) in a malignant tumour. Nature. 379: 19-20. PMID 8538735 DOI: 10.1038/379019A0 |
0.343 |
|
| 1995 |
Tokino T, Thiagalingam S, el-Deiry WS, Waldman T, Kinzler KW, Vogelstein B. p53 tagged sites from human genomic DNA. Human Molecular Genetics. 3: 1537-42. PMID 7833908 DOI: 10.1093/Hmg/3.9.1537 |
0.329 |
|
| 1995 |
Markowitz S, Wang J, Myeroff L, Parsons R, Sun L, Lutterbaugh J, Fan RS, Zborowska E, Kinzler KW, Vogelstein B. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science (New York, N.Y.). 268: 1336-8. PMID 7761852 DOI: 10.1126/Science.7761852 |
0.381 |
|
| 1995 |
Liu B, Nicolaides NC, Markowitz S, Willson JKV, Parsons RE, Jen J, Papadopolous N, Peltomäki P, de la Chapelle A, Hamilton SR, Kinzler KW, Vogelstein B. Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability Nature Genetics. 9: 48-55. PMID 7704024 DOI: 10.1038/Ng0195-48 |
0.444 |
|
| 1995 |
Hamilton SR, Parsons RE, Papadopoulos N, Jen J, Powell SM, Krush AJ, Berk T, Cohen Z, Tetu B, Burger PC, Wood PA, Taqi F, Booker SV, Petersen GM, Offerhaus GJA, ... ... Vogelstein B, et al. The molecular basis of Turcot's syndrome New England Journal of Medicine. 332: 839-847. PMID 7661930 DOI: 10.1056/Nejm199503303321302 |
0.388 |
|
| 1995 |
Parsons R, Li GM, Longley M, Modrich P, Liu B, Berk T, Hamilton SR, Kinzler KW, Vogelstein B. Mismatch repair deficiency in phenotypically normal human cells Science. 268: 738-740. PMID 7632227 DOI: 10.1126/Science.7632227 |
0.415 |
|
| 1995 |
Thiagalingam S, Kinzler KW, Vogelstein B. PAK1, a gene that can regulate p53 activity in yeast. Proceedings of the National Academy of Sciences of the United States of America. 92: 6062-6. PMID 7597081 DOI: 10.1073/Pnas.92.13.6062 |
0.352 |
|
| 1995 |
Vogelstein B, Kinzler KW. Colorectal cancer and the intersection between basic and clinical research. Cold Spring Harbor Symposia On Quantitative Biology. 59: 517-21. PMID 7587107 DOI: 10.1101/Sqb.1994.059.01.057 |
0.313 |
|
| 1995 |
Liu B, Farrington SM, Petersen GM, Hamilton SR, Parsons R, Papadopoulos N, Fujiwara T, Jen J, Kinzler KW, Wyllie AH, Vogelstein B, Dunlop MG. Genetic instability occurs in the majority of young patients with colorectal cancer. Nature Medicine. 1: 348-52. PMID 7585065 DOI: 10.1038/Nm0495-348 |
0.349 |
|
| 1995 |
Nyström-Lahti M, Kristo P, Nicolaides NC, Chang SY, Aaltonen LA, Moisio AL, Järvinen HJ, Mecklin JP, Kinzler KW, Vogelstein B. Founding mutations and Alu-mediated recombination in hereditary colon cancer. Nature Medicine. 1: 1203-6. PMID 7584997 DOI: 10.1038/nm1195-1203 |
0.315 |
|
| 1995 |
Velculescu VE, Zhang L, Vogelstein B, Kinzler KW. Serial analysis of gene expression. Science (New York, N.Y.). 270: 484-7. PMID 7570003 DOI: 10.1126/Science.270.5235.484 |
0.303 |
|
| 1995 |
Papadopoulos N, Leach FS, Kinzler KW, Vogelstein B. Monoallelic mutation analysis (MAMA) for identifying germline mutations. Nature Genetics. 11: 99-102. PMID 7550326 DOI: 10.1038/ng0995-99 |
0.325 |
|
| 1994 |
Parsons R, Li GM, Longley MJ, Fang WH, Papadopoulos N, Jen J, de la Chapelle A, Kinzler KW, Vogelstein B, Modrich P. Hypermutability and mismatch repair deficiency in RER+ tumor cells. Cell. 75: 1227-36. PMID 8261516 DOI: 10.1016/0092-8674(93)90331-J |
0.414 |
|
| 1994 |
Su LK, Vogelstein B, Kinzler KW. Association of the APC tumor suppressor protein with catenins. Science (New York, N.Y.). 262: 1734-7. PMID 8259519 DOI: 10.1126/Science.8259519 |
0.416 |
|
| 1994 |
Kinzler KW, Vogelstein B. Cancer therapy meets p53. The New England Journal of Medicine. 331: 49-50. PMID 8202105 DOI: 10.1056/Nejm199407073310113 |
0.356 |
|
| 1994 |
Cho KR, Oliner JD, Simons JW, Hedrick L, Fearon ER, Preisinger AC, Hedge P, Silverman GA, Vogelstein B. The DCC gene: structural analysis and mutations in colorectal carcinomas. Genomics. 19: 525-31. PMID 8188295 DOI: 10.1006/Geno.1994.1102 |
0.422 |
|
| 1994 |
Chen CY, Oliner JD, Zhan Q, Fornace AJ, Vogelstein B, Kastan MB. Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway. Proceedings of the National Academy of Sciences of the United States of America. 91: 2684-8. PMID 8146175 DOI: 10.1073/Pnas.91.7.2684 |
0.323 |
|
| 1994 |
Pietenpol JA, Tokino T, Thiagalingam S, El-Deiry WS, Kinzler KW, Vogelstein B. Sequence-specific transcriptional activation is essential for growth suppression by p53 Proceedings of the National Academy of Sciences of the United States of America. 91: 1998-2002. PMID 8134338 DOI: 10.1073/Pnas.91.6.1998 |
0.356 |
|
| 1994 |
Papadopoulos N, Nicolaides NC, Wei YF, Ruben SM, Carter KC, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, Adams MD, Venter JC, Hamilton SR, Petersen GM, Watson P, Lynch HT, ... ... Vogelstein B, et al. Mutation of a mutL homolog in hereditary colon cancer Science. 263: 1625-1629. PMID 8128251 DOI: 10.1126/Science.8128251 |
0.424 |
|
| 1994 |
Ueba T, Nosaka T, Takahashi JA, Shibata F, Florkiewicz RZ, Vogelstein B, Oda Y, Kikuchi H, Hatanaka M. Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 9009-13. PMID 8090761 DOI: 10.1073/Pnas.91.19.9009 |
0.413 |
|
| 1994 |
Nicolaldes NC, Papadopoulos N, Liu B, Wel YF, Carter KC, Ruben SM, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, Adams MD, Venter JC, Dunlop MG, Hamilton SR, Petersen GM, ... ... Vogelstein B, et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer Nature. 371: 75-80. PMID 8072530 DOI: 10.1038/371075A0 |
0.432 |
|
| 1994 |
Lynch HT, Drouhard T, Lanspa S, Smyrk T, Lynch P, Lynch J, Vogelstein B, Nyström-Lahti M, Sistonen P, Peltomäki P. Mutation of an mutL homologue in a Navajo family with hereditary nonpolyposis colorectal cancer. Journal of the National Cancer Institute. 86: 1417-9. PMID 8072036 DOI: 10.1093/Jnci/86.18.1417 |
0.396 |
|
| 1994 |
Jen J, Kim H, Piantadosi S, Liu ZF, Levitt RC, Sistonen P, Kinzler KW, Vogelstein B, Hamilton SR. Allelic loss of chromosome 18q and prognosis in colorectal cancer. The New England Journal of Medicine. 331: 213-21. PMID 8015568 DOI: 10.1056/Nejm199407283310401 |
0.339 |
|
| 1994 |
Baas IO, Mulder JW, Offerhaus GJ, Vogelstein B, Hamilton SR. An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms. The Journal of Pathology. 172: 5-12. PMID 7931827 DOI: 10.1002/Path.1711720104 |
0.394 |
|
| 1994 |
Hedrick L, Cho KR, Fearon ER, Wu TC, Kinzler KW, Vogelstein B. The DCC gene product in cellular differentiation and colorectal tumorigenesis. Genes & Development. 8: 1174-83. PMID 7926722 DOI: 10.1101/Gad.8.10.1174 |
0.384 |
|
| 1994 |
Vogelstein B, Kinzler KW. Has the breast cancer gene been found? Cell. 79: 1-3. PMID 7923368 DOI: 10.1016/0092-8674(94)90393-X |
0.319 |
|
| 1994 |
Arthur RR, Grossman SA, Ronnett BM, Bigner SH, Vogelstein B, Shah KV. Lack of association of human polyomaviruses with human brain tumors. Journal of Neuro-Oncology. 20: 55-8. PMID 7807184 DOI: 10.1007/Bf01057961 |
0.311 |
|
| 1994 |
Shiohara M, el-Deiry W, Wada M, Nakamaki T, Takeuchi S, Yang R, Chen D, Vogelstein B, Koeffler H. Absence of WAF1 mutations in a variety of human malignancies Blood. 84: 3781-3784. DOI: 10.1182/Blood.V84.11.3781.Bloodjournal84113781 |
0.311 |
|
| 1993 |
Vogelstein B, Kinzler KW. The multistep nature of cancer. Trends in Genetics : Tig. 9: 138-41. PMID 8516849 DOI: 10.1016/0168-9525(93)90209-Z |
0.437 |
|
| 1993 |
Kinzler KW, Vogelstein B. Cancer. A gene for neurofibromatosis 2. Nature. 363: 495-6. PMID 8505975 DOI: 10.1038/363495A0 |
0.375 |
|
| 1993 |
Oliner JD, Pietenpol JA, Thiagalingam S, Gyuris J, Kinzler KW, Vogelstein B. Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53 Nature. 362: 857-860. PMID 8479525 DOI: 10.1038/362857A0 |
0.305 |
|
| 1993 |
Smith KJ, Johnson KA, Bryan TM, Hill DE, Markowitz S, Willson JK, Paraskeva C, Petersen GM, Hamilton SR, Vogelstein B. The APC gene product in normal and tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 2846-50. PMID 8385345 DOI: 10.1073/Pnas.90.7.2846 |
0.395 |
|
| 1993 |
el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B. WAF1, a potential mediator of p53 tumor suppression. Cell. 75: 817-25. PMID 8242752 DOI: 10.1016/0092-8674(93)90500-P |
0.364 |
|
| 1993 |
Luongo C, Gould KA, Su LK, Kinzler KW, Vogelstein B, Dietrich W, Lander ES, Moser AR. Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse. Genomics. 15: 3-8. PMID 8094372 DOI: 10.1006/Geno.1993.1002 |
0.383 |
|
| 1993 |
Cho KR, Vogelstein B. Suppressor gene alterations in the colorectal adenoma-carcinoma sequence. Journal of Cellular Biochemistry. Supplement. 137-41. PMID 1469893 DOI: 10.1002/Jcb.240501124 |
0.449 |
|
| 1993 |
Hedrick L, Cho KR, Boyd J, Risinger J, Vogelstein B. DCC: a tumor suppressor gene expressed on the cell surface. Cold Spring Harbor Symposia On Quantitative Biology. 57: 345-51. PMID 1339669 DOI: 10.1101/Sqb.1992.057.01.039 |
0.334 |
|
| 1993 |
Nakamura Y, Nishisho I, Kinzler KW, Vogelstein B, Miyoshi Y, Miki Y, Ando H, Horii A. Mutations of the APC (adenomatous polyposis coli) gene in FAP (familial polyposis coli) patients and in sporadic colorectal tumors. The Tohoku Journal of Experimental Medicine. 168: 141-7. PMID 1339098 DOI: 10.1620/Tjem.168.141 |
0.442 |
|
| 1993 |
Nagase H, Miyoshi Y, Horii A, Aoki T, Petersen GM, Vogelstein B, Maher E, Ogawa M, Maruyama M, Utsunomiya J. Screening for germ-line mutations in familial adenomatous polyposis patients: 61 new patients and a summary of 150 unrelated patients. Human Mutation. 1: 467-73. PMID 1338764 DOI: 10.1002/Humu.1380010603 |
0.381 |
|
| 1992 |
Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature. 358: 80-3. PMID 1614537 DOI: 10.1038/358080A0 |
0.379 |
|
| 1992 |
Kern SE, Pietenpol JA, Thiagalingam S, Seymour A, Kinzler KW, Vogelstein B. Oncogenic forms of p53 inhibit p53-regulated gene expression Science. 256: 827-830. PMID 1589764 DOI: 10.1126/Science.1589764 |
0.359 |
|
| 1992 |
Offerhaus GJ, De Feyter EP, Cornelisse CJ, Tersmette KW, Floyd J, Kern SE, Vogelstein B, Hamilton SR. The relationship of DNA aneuploidy to molecular genetic alterations in colorectal carcinoma. Gastroenterology. 102: 1612-9. PMID 1568571 DOI: 10.1016/0016-5085(92)91721-F |
0.338 |
|
| 1992 |
Sidransky D, Tokino T, Hamilton SR, Kinzler KW, Levin B, Frost P, Vogelstein B. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science (New York, N.Y.). 256: 102-5. PMID 1566048 DOI: 10.1126/Science.1566048 |
0.388 |
|
| 1992 |
Wong AJ, Ruppert JM, Bigner SH, Grzeschik CH, Humphrey PA, Bigner DS, Vogelstein B. Structural alterations of the epidermal growth factor receptor gene in human gliomas. Proceedings of the National Academy of Sciences of the United States of America. 89: 2965-9. PMID 1557402 DOI: 10.1073/Pnas.89.7.2965 |
0.392 |
|
| 1992 |
Nigro JM, Sikorski R, Reed SI, Vogelstein B. Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae. Molecular and Cellular Biology. 12: 1357-65. PMID 1545817 DOI: 10.1128/Mcb.12.3.1357 |
0.337 |
|
| 1992 |
Bennett WP, Hollstein MC, Hsu IC, Sidransky D, Lane DP, Vogelstein B, Harris CC. Mutational spectra and immunohistochemical analyses of p53 in human cancers. Chest. 101: 19S-20S. PMID 1541189 DOI: 10.1378/Chest.101.3_Supplement.19S |
0.412 |
|
| 1992 |
Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, Vogelstein B, Kinzler KW. APC mutations occur early during colorectal tumorigenesis. Nature. 359: 235-7. PMID 1528264 DOI: 10.1038/359235A0 |
0.419 |
|
| 1992 |
Cho KR, Vogelstein B. Genetic alterations in the adenoma--carcinoma sequence. Cancer. 70: 1727-31. PMID 1516027 DOI: 10.1002/1097-0142(19920915)70:4+<1727::AID-CNCR2820701613>3.0.CO;2-P |
0.352 |
|
| 1992 |
Sidransky D, Frost P, Von Eschenbach A, Oyasu R, Preisinger AC, Vogelstein B. Clonal origin of bladder cancer. The New England Journal of Medicine. 326: 737-40. PMID 1445507 DOI: 10.1056/Nejm199203123261104 |
0.35 |
|
| 1992 |
Kastan MB, Zhan Q, el-Deiry WS, Carrier F, Jacks T, Walsh WV, Plunkett BS, Vogelstein B, Fornace AJ. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell. 71: 587-97. PMID 1423616 DOI: 10.1016/0092-8674(92)90593-2 |
0.37 |
|
| 1992 |
Su LK, Kinzler KW, Vogelstein B, Preisinger AC, Moser AR, Luongo C, Gould KA, Dove WF. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science (New York, N.Y.). 256: 668-70. PMID 1350108 DOI: 10.1126/Science.1350108 |
0.45 |
|
| 1992 |
Miyoshi Y, Nishisho I, Miki Y, Mori T, Kinzler KW, Vogelstein B, Nakamura Y. Insertion/deletion polymorphism and other restriction fragment length polymorphisms in the MCC gene. Japanese Journal of Cancer Research : Gann. 83: 10-4. PMID 1347524 DOI: 10.1111/J.1349-7006.1992.Tb02344.X |
0.33 |
|
| 1992 |
Lawlor KG, Telang NT, Osborne MP, Schaapveld RQ, Cho KR, Vogelstein B, Narayanan R. Antisense RNA to the putative tumor suppressor gene "deleted in colorectal cancer" transforms fibroblasts. Annals of the New York Academy of Sciences. 660: 283-5. PMID 1340136 DOI: 10.1111/J.1749-6632.1992.Tb21086.X |
0.37 |
|
| 1992 |
Kinzler KW, Vogelstein B. The colorectal cancer gene hunt: current findings. Hospital Practice (Office Ed.). 27: 51-8. PMID 1331139 DOI: 10.1080/21548331.1992.11705522 |
0.419 |
|
| 1992 |
Miyoshi Y, Ando H, Nagase H, Nishisho I, Horii A, Miki Y, Mori T, Utsunomiya J, Baba S, Petersen GM, Hamilton SR, Kinzler KW, Vogelstein B, Nakamura Y. Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients. Proceedings of the National Academy of Sciences of the United States of America. 89: 4452-4456. PMID 1316610 DOI: 10.1073/Pnas.89.10.4452 |
0.395 |
|
| 1992 |
Sidransky D, Mikkelsen T, Schwechheimer K, Rosenblum ML, Cavanee W, Vogelstein B. Clonal expansion of p53 mutant cells is associated with brain tumour progression. Nature. 355: 846-7. PMID 1311419 DOI: 10.1038/355846A0 |
0.369 |
|
| 1992 |
El-Deiry WS, Kern SE, Pietenpol JA, Kinzler KW, Vogelstein B. Definition of a consensus binding site for p53 Nature Genetics. 1: 45-49. PMID 1301998 DOI: 10.1038/Ng0492-45 |
0.305 |
|
| 1992 |
Su L, Kinzler KW, Vogelstein B, Preisinger AC, Moser AR, Luongo C, Gould KA, Dove WF. Corrections and Clarifications: Multiple Intestinal Neoplasia Caused By a Mutation in the Murine Homolog of the APC Gene Science. 256: 1114-1114. DOI: 10.1126/Science.256.5060.1114-C |
0.384 |
|
| 1991 |
Vogelstein B, Civin CI, Preisinger AC, Krischer JP, Steuber P, Ravindranath Y, Weinstein H, Elfferich P, Bos J. RAS gene mutations in childhood acute myeloid leukemia: a Pediatric Oncology Group study. Genes, Chromosomes & Cancer. 2: 159-62. PMID 2278970 DOI: 10.1002/Gcc.2870020212 |
0.377 |
|
| 1991 |
Vogelstein B. Cancer. A deadly inheritance. Nature. 348: 681-2. PMID 2259380 DOI: 10.1038/348681A0 |
0.358 |
|
| 1991 |
Meltzer SJ, Yin J, Huang Y, McDaniel TK, Newkirk C, Iseri O, Vogelstein B, Resau JH. Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction. Proceedings of the National Academy of Sciences of the United States of America. 88: 4976-80. PMID 2052580 DOI: 10.1073/Pnas.88.11.4976 |
0.371 |
|
| 1991 |
Kern SE, Kinzler KW, Bruskin A, Jarosz D, Friedman P, Prives C, Vogelstein B. Identification of p53 as a sequence-specific DNA-binding protein. Science (New York, N.Y.). 252: 1708-11. PMID 2047879 DOI: 10.1126/Science.2047879 |
0.4 |
|
| 1991 |
Sidransky D, Eschenbach AV, Tsai YC, Jones P, Summerhayes I, Marshall F, Paul M, Green P, Hamilton SR, Frost P, Vogelstein B. Identification of p53 gene mutations in bladder cancers and urine samples Science. 252: 706-709. PMID 2024123 DOI: 10.1126/Science.2024123 |
0.471 |
|
| 1991 |
Hollstein M, Sidransky D, Vogelstein B, Harris CC. p53 mutations in human cancers. Science (New York, N.Y.). 253: 49-53. PMID 1905840 DOI: 10.1126/Science.1905840 |
0.437 |
|
| 1991 |
Itaya T, Fearon E, Fiesinger T, Hunt B, Vogelstein B, Frost P. Immunogenicity of a non-class I MHC expressing murine tumor transfected with the influenza virus hemagglutinin or murine interleukin-2 genes. Cancer Immunology, Immunotherapy : Cii. 33: 267-73. PMID 1905583 DOI: 10.1007/Bf01744947 |
0.3 |
|
| 1991 |
Kinzler KW, Nilbert MC, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hamilton SR, Hedge P, Markham A. Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science (New York, N.Y.). 251: 1366-70. PMID 1848370 DOI: 10.1126/Science.1848370 |
0.436 |
|
| 1991 |
Ruppert JM, Vogelstein B, Kinzler KW. The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A. Molecular and Cellular Biology. 11: 1724-8. PMID 1825351 DOI: 10.1128/Mcb.11.3.1724 |
0.308 |
|
| 1991 |
Kovach JS, McGovern RM, Cassady JD, Swanson SK, Wold LE, Vogelstein B, Sommer SS. Direct sequencing from touch preparations of human carcinomas: analysis of p53 mutations in breast carcinomas. Journal of the National Cancer Institute. 83: 1004-9. PMID 1712853 DOI: 10.1093/Jnci/83.14.1004 |
0.4 |
|
| 1991 |
Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, Koyama K, Utsunomiya J, Baba S, Hedge P, Markham A, Krush AJ, Petersen G, Hamilton SR, Nilbert MC, ... ... Vogelstein B, et al. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients Science. 253: 665-669. PMID 1651563 DOI: 10.1126/Science.1651563 |
0.419 |
|
| 1991 |
Kinzler KW, Nilbert MC, Su LK, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hedge P, McKechnie D. Identification of FAP locus genes from chromosome 5q21. Science (New York, N.Y.). 253: 661-5. PMID 1651562 DOI: 10.1126/Science.1651562 |
0.383 |
|
| 1991 |
Bargonetti J, Friedman PN, Kern SE, Vogelstein B, Prives C. Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication Cell. 65: 1083-1091. PMID 1646078 DOI: 10.1016/0092-8674(91)90560-L |
0.351 |
|
| 1990 |
Diller L, Kassel J, Nelson CE, Gryka MA, Litwak G, Gebhardt M, Bressac B, Ozturk M, Baker SJ, Vogelstein B. p53 functions as a cell cycle control protein in osteosarcomas. Molecular and Cellular Biology. 10: 5772-81. PMID 2233717 DOI: 10.1128/Mcb.10.11.5772 |
0.382 |
|
| 1990 |
Baker SJ, Markowitz S, Fearon ER, Willson JK, Vogelstein B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science (New York, N.Y.). 249: 912-5. PMID 2144057 DOI: 10.1126/Science.2144057 |
0.388 |
|
| 1990 |
Fearon ER, Pardoll DM, Itaya T, Golumbek P, Levitsky HI, Simons JW, Karasuyama H, Vogelstein B, Frost P. Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response. Cell. 60: 397-403. PMID 2137372 DOI: 10.1016/0092-8674(90)90591-2 |
0.326 |
|
| 1990 |
Ruppert JM, Vogelstein B, Arheden K, Kinzler KW. GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity. Molecular and Cellular Biology. 10: 5408-15. PMID 2118997 DOI: 10.1128/Mcb.10.10.5408 |
0.318 |
|
| 1990 |
Kinzler KW, Vogelstein B. The GLI gene encodes a nuclear protein which binds specific sequences in the human genome. Molecular and Cellular Biology. 10: 634-42. PMID 2105456 DOI: 10.1128/Mcb.10.2.634 |
0.311 |
|
| 1990 |
Humphrey PA, Wong AJ, Vogelstein B, Zalutsky MR, Fuller GN, Archer GE, Friedman HS, Kwatra MM, Bigner SH, Bigner DD. Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 87: 4207-11. PMID 1693434 DOI: 10.1073/Pnas.87.11.4207 |
0.319 |
|
| 1990 |
Bigner SH, Vogelstein B. Cytogenetics and molecular genetics of malignant gliomas and medulloblastoma. Brain Pathology (Zurich, Switzerland). 1: 12-8. PMID 1669688 DOI: 10.1111/J.1750-3639.1990.Tb00633.X |
0.358 |
|
| 1990 |
Fuller GN, Burger PC, Schold SC, Preisinqer A, Wong AJ, Bigner PP, Vogelstein B, Bigner SH. GENE AMPLIFICATION IN HUMAN GLIOMAS Journal of Neuropathology and Experimental Neurology. 49: 320. DOI: 10.1097/00005072-199005000-00183 |
0.307 |
|
| 1989 |
Schackert HK, Itaya T, Schackert G, Fearon E, Vogelstein B, Frost P. Systemic immunity against a murine colon tumor (CT-26) produced by immunization with syngeneic cells expressing a transfected viral gene product. International Journal of Cancer. 43: 823-7. PMID 2714886 DOI: 10.1002/Ijc.2910430514 |
0.311 |
|
| 1989 |
Kern SE, Fearon ER, Tersmette KW, Enterline JP, Leppert M, Nakamura Y, White R, Vogelstein B, Hamilton SR. Clinical and pathological associations with allelic loss in colorectal carcinoma [corrected]. Jama. 261: 3099-103. PMID 2654431 DOI: 10.1001/Jama.261.21.3099 |
0.368 |
|
| 1989 |
Baker SJ, Fearon ER, Nigro JM, Hamilton SR, Preisinger AC, Jessup JM, vanTuinen P, Ledbetter DH, Barker DF, Nakamura Y, White R, Vogelstein B. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science (New York, N.Y.). 244: 217-21. PMID 2649981 DOI: 10.1126/Science.2649981 |
0.39 |
|
| 1989 |
Vogelstein B, Fearon ER, Kern SE, Hamilton SR, Preisinger AC, Nakamura Y, White R. Allelotype of colorectal carcinomas. Science (New York, N.Y.). 244: 207-11. PMID 2565047 DOI: 10.1126/Science.2565047 |
0.357 |
|
| 1988 |
Bigner SH, Burger PC, Wong AJ, Werner MH, Hamilton SR, Muhlbaier LH, Vogelstein B, Bigner DD. Gene amplification in malignant human gliomas: clinical and histopathologic aspects. Journal of Neuropathology and Experimental Neurology. 47: 191-205. PMID 3367154 DOI: 10.1097/00005072-198805000-00001 |
0.375 |
|
| 1988 |
Hamilton SR, Vogelstein B. Point mutations in human neoplasia. The Journal of Pathology. 154: 205-6. PMID 3280768 DOI: 10.1002/Path.1711540302 |
0.35 |
|
| 1988 |
Ruppert JM, Kinzler KW, Wong AJ, Bigner SH, Kao FT, Law ML, Seuanez HN, O'Brien SJ, Vogelstein B. The GLI-Kruppel family of human genes. Molecular and Cellular Biology. 8: 3104-13. PMID 2850480 DOI: 10.1128/Mcb.8.8.3104 |
0.311 |
|
| 1988 |
Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smits AM, Bos JL. Genetic alterations during colorectal-tumor development. The New England Journal of Medicine. 319: 525-32. PMID 2841597 DOI: 10.1056/Nejm198809013190901 |
0.396 |
|
| 1988 |
Kinzler KW, Ruppert JM, Bigner SH, Vogelstein B. The GLI gene is a member of the Kruppel family of zinc finger proteins. Nature. 332: 371-4. PMID 2832761 DOI: 10.1038/332371A0 |
0.382 |
|
| 1988 |
Zehnbauer BA, Small D, Brodeur GM, Seeger R, Vogelstein B. Characterization of N-myc amplification units in human neuroblastoma cells. Molecular and Cellular Biology. 8: 522-30. PMID 2832725 DOI: 10.1128/Mcb.8.2.522 |
0.337 |
|
| 1987 |
Feinberg AP, Vogelstein B. Alterations in DNA methylation in human colon neoplasia. Seminars in Surgical Oncology. 3: 149-51. PMID 3659719 DOI: 10.1002/Ssu.2980030304 |
0.565 |
|
| 1987 |
Bos JL, Vries MVd, Van Der Eb AJ, Fearon ER, Vogelstein B, Hamilton SR, Van Boom JH. Prevalence of ras gene mutations in human colorectal cancers Nature. 327: 293-297. PMID 3587348 DOI: 10.1038/327293A0 |
0.417 |
|
| 1987 |
Kinzler KW, Bigner SH, Bigner DD, Trent JM, Law ML, O'Brien SJ, Wong AJ, Vogelstein B. Identification of an amplified, highly expressed gene in a human glioma. Science (New York, N.Y.). 236: 70-3. PMID 3563490 DOI: 10.1126/Science.3563490 |
0.349 |
|
| 1987 |
Bigner SH, Wong AJ, Mark J, Muhlbaier LH, Kinzler KW, Vogelstein B, Bigner DD. Relationship between gene amplification and chromosomal deviations in malignant human gliomas. Cancer Genetics and Cytogenetics. 29: 165-70. PMID 3478127 DOI: 10.1016/0165-4608(87)90045-8 |
0.369 |
|
| 1987 |
Wong AJ, Bigner SH, Bigner DD, Kinzler KW, Hamilton SR, Vogelstein B. Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proceedings of the National Academy of Sciences of the United States of America. 84: 6899-903. PMID 3477813 DOI: 10.1073/Pnas.84.19.6899 |
0.344 |
|
| 1987 |
Fearon ER, Hamilton SR, Vogelstein B. Clonal analysis of human colorectal tumors. Science (New York, N.Y.). 238: 193-7. PMID 2889267 DOI: 10.1126/Science.2889267 |
0.341 |
|
| 1987 |
Baylin S, Fearon E, Vogelstein B, de Bustros A, Sharkis S, Burke P, Staal S, Nelkin B. Hypermethylation of the 5' region of the calcitonin gene is a property of human lymphoid and acute myeloid malignancies Blood. 70: 412-417. DOI: 10.1182/Blood.V70.2.412.Bloodjournal702412 |
0.343 |
|
| 1987 |
Bigner SH, Burger PC, Wong AJ, Kinzier KK, Hamilton SR, Vogelstein B, Bigner DD. MORPHOLOGIC CHARACTERISTICS OF MALIGNANT HUMAN GLIOMAS (MHG) WITH GENE AMPLIFICATION Journal of Neuropathology and Experimental Neurology. 46: 373. DOI: 10.1097/00005072-198705000-00130 |
0.318 |
|
| 1986 |
Wong AJ, Ruppert JM, Eggleston J, Hamilton SR, Baylin SB, Vogelstein B. Gene amplification of c-myc and N-myc in small cell carcinoma of the lung. Science (New York, N.Y.). 233: 461-4. PMID 3014659 DOI: 10.1126/Science.3014659 |
0.331 |
|
| 1986 |
Kinzler KW, Zehnbauer BA, Brodeur GM, Seeger RC, Trent JM, Meltzer PS, Vogelstein B. Amplification units containing human N-myc and c-myc genes Proceedings of the National Academy of Sciences of the United States of America. 83: 1031-1035. PMID 3006024 DOI: 10.1073/Pnas.83.4.1031 |
0.324 |
|
| 1986 |
Trent J, Meltzer P, Rosenblum M, Harsh G, Kinzler K, Mashal R, Feinberg A, Vogelstein B. Evidence for rearrangement, amplification, and expression of c-myc in a human glioblastoma Proceedings of the National Academy of Sciences of the United States of America. 83: 470-473. PMID 3001737 DOI: 10.1073/Pnas.83.2.470 |
0.59 |
|
| 1986 |
Meltzer P, Kinzler K, Vogelstein B, Trent JM. Gene amplification in cancer: A molecular cytogenetic approach Cancer Genetics and Cytogenetics. 19: 93-99. PMID 2998586 DOI: 10.1016/0165-4608(86)90376-6 |
0.38 |
|
| 1985 |
Fearon ER, Feinberg AP, Hamilton SH, Vogelstein B. Loss of genes on the short arm of chromosome 11 in bladder cancer. Nature. 318: 377-80. PMID 2999610 DOI: 10.1038/318377A0 |
0.574 |
|
| 1985 |
Vogelstein B, Fearon ER, Hamilton SR, Feinberg AP. Use of restriction fragment length polymorphisms to determine the clonal origin of human tumors. Science (New York, N.Y.). 227: 642-5. PMID 2982210 DOI: 10.1126/Science.2982210 |
0.587 |
|
| 1985 |
Goelz SE, Vogelstein B, Hamilton SR, Feinberg AP. Hypomethylation of DNA from benign and malignant human colon neoplasms. Science (New York, N.Y.). 228: 187-90. PMID 2579435 DOI: 10.1126/Science.2579435 |
0.538 |
|
| 1984 |
Feinberg AP, Vogelstein B. "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum. Analytical Biochemistry. 137: 266-7. PMID 6329026 DOI: 10.1016/0003-2697(84)90381-6 |
0.446 |
|
| 1984 |
Fearon ER, Vogelstein B, Feinberg AP. Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours. Nature. 309: 176-8. PMID 6325939 DOI: 10.1038/309176A0 |
0.56 |
|
| 1983 |
Feinberg AP, Vogelstein B, Droller MJ, Baylin SB, Nelkin BD. Mutation affecting the 12th amino acid of the c-Ha-ras oncogene product occurs infrequently in human cancer. Science (New York, N.Y.). 220: 1175-7. PMID 6304875 DOI: 10.1126/Science.6304875 |
0.627 |
|
| 1983 |
Feinberg AP, Vogelstein B. Hypomethylation of ras oncogenes in primary human cancers. Biochemical and Biophysical Research Communications. 111: 47-54. PMID 6187346 DOI: 10.1016/S0006-291X(83)80115-6 |
0.32 |
|
| 1983 |
Feinberg AP, Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature. 301: 89-92. PMID 6185846 DOI: 10.1038/301089A0 |
0.606 |
|
| 1982 |
Vogelstein B, Dzintis RZ, Dintzis HM. Specific cellular stimulation in the primary immune response: A quantized model Proceedings of the National Academy of Sciences of the United States of America. 79: 395-399. PMID 6952192 |
0.62 |
|
| 1982 |
Dintzis RZ, Vogelstein B, Dintzis HM. Specific cellular stimulation in the primary immune response: Experimental test of a quantized model Proceedings of the National Academy of Sciences of the United States of America. 79: 884-888. PMID 6950432 |
0.615 |
|
| 1980 |
Vogelstein B, Pardoll DM, Coffey DS. Supercoiled loops and eukaryotic DNA replication Cell. 22: 79-85. PMID 7428042 DOI: 10.1016/0092-8674(80)90156-7 |
0.454 |
|
| 1980 |
Pardoll DM, Vogelstein B, Coffey DS. A fixed site of DNA replication in eucaryotic cells Cell. 19: 527-536. PMID 7357619 DOI: 10.1016/0092-8674(80)90527-9 |
0.455 |
|
| 1979 |
Shaper JH, Pardoll DM, Kaufmann SH, Barrack ER, Vogelstein B, Coffey DS. The relationship of the nuclear matrix to cellular structure and function Advances in Enzyme Regulation. 17: 213-220,IN3-IN6,221-. DOI: 10.1016/0065-2571(79)90015-3 |
0.432 |
|
| 1976 |
Dintzis HM, Dintzis RZ, Vogelstein B. Molecular determinants of immunogenicity: The immunon model of immune response Proceedings of the National Academy of Sciences of the United States of America. 73: 3671-3675. PMID 62364 |
0.61 |
|
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